Pub Date : 2014-05-01DOI: 10.13189/APP.2014.020302
Quyen Bach, A. Lovett, T. Pounds, Pamela M. Moye
In 2008, the American Society of Health-System Pharmacists introduced the Pharmacy Practice Model Initiative (PPMI). The goal of this model is to promote pharmacy leaders, better manage resources, and increase focus on patient-centered and team-based care. Few studies have assessed the model's implementation. PubMed and CINAHL were searched using keywords "pharmacy practice model," "organizational," and the MeSH term, "organizational," from 2008 to 2013. Of the forty-nine findings (articles and summit highlights), two case studies met the inclusion criteria. The first case study involved the University of Minnesota Medical Center, a multi-campus academic medical center. This facility used technology such as pagers for decentralized technicians, computerized provider order entry, and wireless computers on wheels. The implementation teams worked on clinical and distributive functions allowing for consistency in care and improved employee satisfaction. The second case study involved Providence Health & Services, a multihospital system in Washington State and Montana. These facilities used technology such as automated dispensing cabinets, order-image scanners, and automated telephone trees to route calls. The outcome was a positive economic impact with a return on investment of $709,321. An important finding was the lack of research assessing the implementation of the PPMI. Based on positive findings, it is evident that further research is warranted.
2008年，美国卫生系统药剂师协会(American Society of Health-System Pharmacists)推出了Pharmacy Practice Model Initiative (PPMI)。这种模式的目标是促进药房领导，更好地管理资源，并增加对以患者为中心和团队为基础的护理的关注。很少有研究评估该模型的实施情况。从2008年到2013年，PubMed和CINAHL使用关键词“药房实践模型”、“组织”和MeSH术语“组织”进行了搜索。在49项发现(文章和峰会要点)中，有两个案例研究符合纳入标准。第一个案例研究涉及明尼苏达大学医学中心，一个多校区的学术医疗中心。该设施使用了诸如分散技术人员的寻呼机、计算机化的供应商订单输入和车轮上的无线计算机等技术。实施团队致力于临床和分配功能，以确保护理的一致性和提高员工满意度。第二个案例研究涉及普罗维登斯健康与服务，这是一个位于华盛顿州和蒙大拿州的多医院系统。这些设施使用诸如自动点胶柜、订单图像扫描仪和自动电话树等技术来路由呼叫。结果产生了积极的经济影响，投资回报为709,321美元。一个重要的发现是缺乏评估PPMI实施情况的研究。基于积极的发现，显然有必要进行进一步的研究。
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Pub Date : 2014-03-01DOI: 10.13189/APP.2014.020203
M. Dzhafarov, F. I. Vasilevich
This review discusses the landmark anthelminthic substances – traditional medicine components, different categories of pluripotential synthetic and naturally occurring compounds. Much attention is paid to the sections devoted to recent discoveries (Emodepside, Monepantel, Derquantel, Tribendimidine) and to some promising works. The review is also focused on some aspects of molecular mechanisms of action of anthelminthic substances and of helminth adaptation to anthelminthic substances, and on alternative worming treatment options. Based on the systemic analysis of particular features of the chemical structure of anthelminthic substances, the hypothesis on the viability of the targeted search for such compounds among the derivatives of conditionally progenitor cyclic hydrocarbons – benzene, indene, naphthalene, 1Н-cyclopenth [a]-naphthalene , anthracene and phenanthrene – by alternating absolutely unsaturated and saturated structures, including heterocyclic analogues containing nitrogen, oxygen and sulfur and different substitutes and functional groups, was voiced.
{"title":"Ecological, Physiological and Biochemical Adaptation in Helminth: Trends in Evolution of Anthelminthic Chemical Agents","authors":"M. Dzhafarov, F. I. Vasilevich","doi":"10.13189/APP.2014.020203","DOIUrl":"https://doi.org/10.13189/APP.2014.020203","url":null,"abstract":"This review discusses the landmark anthelminthic substances – traditional medicine components, different categories of pluripotential synthetic and naturally occurring compounds. Much attention is paid to the sections devoted to recent discoveries (Emodepside, Monepantel, Derquantel, Tribendimidine) and to some promising works. The review is also focused on some aspects of molecular mechanisms of action of anthelminthic substances and of helminth adaptation to anthelminthic substances, and on alternative worming treatment options. Based on the systemic analysis of particular features of the chemical structure of anthelminthic substances, the hypothesis on the viability of the targeted search for such compounds among the derivatives of conditionally progenitor cyclic hydrocarbons – benzene, indene, naphthalene, 1Н-cyclopenth [a]-naphthalene , anthracene and phenanthrene – by alternating absolutely unsaturated and saturated structures, including heterocyclic analogues containing nitrogen, oxygen and sulfur and different substitutes and functional groups, was voiced.","PeriodicalId":7378,"journal":{"name":"Advances in Pharmacology and Pharmacy","volume":"30 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2014-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84831806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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