A: Patient with little effort. Top: Volume Controlled Ventilation: airway pressure in cmH2O in yellow, constant flow in L/min in pink. Middle: Pressure controlled ventilation: airway pressure in cmH2O in yellow, decelerating flow in L/min in pink. Bottom: Esophageal pressure in cmH2O. B: Patient with high effort. Top: Volume Controlled Ventilation: airway pressure with convex negative deflection during trigger and first half of inspiration (blue arrow). Middle: Pressure controlled ventilation: airway pressure with negative deflection during the trigger (yellow arrow) and slight convex deflection (green arrow), concave deflection in the flow (orange arrow). Bottom: Convex deflection in esophageal pressure (grey arrow).
{"title":"Patient effort at a glance","authors":"Mia Shokry, Kimiyo H. Yamasaki","doi":"10.53097/jmv.10038","DOIUrl":"https://doi.org/10.53097/jmv.10038","url":null,"abstract":"A: Patient with little effort. Top: Volume Controlled Ventilation: airway pressure in cmH2O in yellow, constant flow in L/min in pink. Middle: Pressure controlled ventilation: airway pressure in cmH2O in yellow, decelerating flow in L/min in pink. Bottom: Esophageal pressure in cmH2O. B: Patient with high effort. Top: Volume Controlled Ventilation: airway pressure with convex negative deflection during trigger and first half of inspiration (blue arrow). Middle: Pressure controlled ventilation: airway pressure with negative deflection during the trigger (yellow arrow) and slight convex deflection (green arrow), concave deflection in the flow (orange arrow). Bottom: Convex deflection in esophageal pressure (grey arrow).","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42288252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Corona virus 2019 (COVID-19) pandemic spread in the world as a great medical crisis. Its pathophysiology, manifestations, complications, and management are not completely defined, yet. In this study frequency of alveolar air leak in critically ill COVID-19 subjects is explored. Methods A total of 820 critically ill COVID-19 subjects who admitted with respiratory insufficiency to ICUs of Sina University Hospital from March 2020 to June 2021 were included. All their chest x ray (CXR) and Computed tomography (CT) of chest were reviewed. All alveolar air leak episodes (pneumothorax, pneumomediastinum, pneumopericardium, subcutaneous emphysema) suspected films reviewed by attending intensivist and radiologist. Results Of the 820 ill COVID-19 subjects in ICUs, 492(60%) were male, and 328 (40%) were female. The Mean age of 820 subjects was 60.84 + 16.82. 584 (71.22%) of subjects were non-intubated, and 236 (28.78%) were intubated. Alveolar air leak occurred in 98 (11.95%) of subjects. Alveolar air leak episodes include pneumothorax in 26 (3.17%), subcutaneous emphysema in 72 (8.78%), pneumomediastinum in 9 (1.10%), and pneumopericardium in 1 (0.12%) of subjects. The mean age in non-intubated subjects was 59.65 + 16.84, and for intubated subjects was 63 + 16.42. There was a significant difference in age between the groups who get intubated, versus not intubated P 0.001. Of the 584 non-intubated subjects, 31 (5.31%) had subcutaneous emphysema, of the 236 intubated subjects, 41 (17.37%) had subcutaneous emphysema. Difference between groups was statistically significant, P <0.001. When we compared intubated and non-intubated patients in case of total numbers of alveolar air leak episodes, the difference was statistically significant P <0.001. Conclusion According to this study, intubation was implemented more in older patients. Also, invasive ventilation was significantly associated with subcutaneous emphysema and total number of alveolar air leak episodes. In every patient with exaggeration of hypoxia, dyspnea or chest pain, pneumothorax should be kept in mind as a differential diagnosis. Keywords: COVID-19; Respiratory failure; Alveolar air leak; Paraseptal emphysema
{"title":"Alveolar air leak and paraseptal emphysema in severe COVID-19 disease","authors":"A. Najafi, F. Fallahian, A. Ahmadi, K. Bakhtavar","doi":"10.53097/jmv.10034","DOIUrl":"https://doi.org/10.53097/jmv.10034","url":null,"abstract":"Background Corona virus 2019 (COVID-19) pandemic spread in the world as a great medical crisis. Its pathophysiology, manifestations, complications, and management are not completely defined, yet. In this study frequency of alveolar air leak in critically ill COVID-19 subjects is explored. Methods A total of 820 critically ill COVID-19 subjects who admitted with respiratory insufficiency to ICUs of Sina University Hospital from March 2020 to June 2021 were included. All their chest x ray (CXR) and Computed tomography (CT) of chest were reviewed. All alveolar air leak episodes (pneumothorax, pneumomediastinum, pneumopericardium, subcutaneous emphysema) suspected films reviewed by attending intensivist and radiologist. Results Of the 820 ill COVID-19 subjects in ICUs, 492(60%) were male, and 328 (40%) were female. The Mean age of 820 subjects was 60.84 + 16.82. 584 (71.22%) of subjects were non-intubated, and 236 (28.78%) were intubated. Alveolar air leak occurred in 98 (11.95%) of subjects. Alveolar air leak episodes include pneumothorax in 26 (3.17%), subcutaneous emphysema in 72 (8.78%), pneumomediastinum in 9 (1.10%), and pneumopericardium in 1 (0.12%) of subjects. The mean age in non-intubated subjects was 59.65 + 16.84, and for intubated subjects was 63 + 16.42. There was a significant difference in age between the groups who get intubated, versus not intubated P 0.001. Of the 584 non-intubated subjects, 31 (5.31%) had subcutaneous emphysema, of the 236 intubated subjects, 41 (17.37%) had subcutaneous emphysema. Difference between groups was statistically significant, P <0.001. When we compared intubated and non-intubated patients in case of total numbers of alveolar air leak episodes, the difference was statistically significant P <0.001. Conclusion According to this study, intubation was implemented more in older patients. Also, invasive ventilation was significantly associated with subcutaneous emphysema and total number of alveolar air leak episodes. In every patient with exaggeration of hypoxia, dyspnea or chest pain, pneumothorax should be kept in mind as a differential diagnosis. Keywords: COVID-19; Respiratory failure; Alveolar air leak; Paraseptal emphysema","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46241684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ventilator care is synonymous with Intensive care. These devices are electromechanical and as such can fail. Most failures are without patient incident, injury, and harm. The FDA requires manufacturers who learn of malfunction, injury or death while operating their product to report to the agency via the Manufacturer and User Facility Device Experience database. I reviewed 500 recent events reported to the FDA and found an increasing trend from 2020 to 2021 in hospital ventilator malfunction reports. Examination of these reports is critical to assuring quality ventilator care. The author concluded that intensive training on the device characteristics and feature and a more rigorous examination of ventilator performance between patients may assist in reducing device malfunctions. Keywords: Mechanical ventilation, Ventilator malfunction, FDA
{"title":"A review of hospital based ventilator malfunctions reported to the FDA in 2021","authors":"Stephen Tunnell","doi":"10.53097/jmv.10037","DOIUrl":"https://doi.org/10.53097/jmv.10037","url":null,"abstract":"Ventilator care is synonymous with Intensive care. These devices are electromechanical and as such can fail. Most failures are without patient incident, injury, and harm. The FDA requires manufacturers who learn of malfunction, injury or death while operating their product to report to the agency via the Manufacturer and User Facility Device Experience database. I reviewed 500 recent events reported to the FDA and found an increasing trend from 2020 to 2021 in hospital ventilator malfunction reports. Examination of these reports is critical to assuring quality ventilator care. The author concluded that intensive training on the device characteristics and feature and a more rigorous examination of ventilator performance between patients may assist in reducing device malfunctions. Keywords: Mechanical ventilation, Ventilator malfunction, FDA","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46154958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The importance of corticosteroids in the therapy of COVID-19 has been controversial. However, as the world develops a better understanding regarding the pathophysiology of COVID-19, we are realizing that suppressing the host immune response may reduce lung inflammation preventing further complications. In addition, more high-quality randomized controlled trials, meta-analysis, and review articles are being published discussing the role of corticosteroids. Majority of these studies concluded that corticosteroids are beneficial for hospitalized severely ill COVID-19 patients requiring supplemental oxygen. To date, therapeutic guidelines for COVID-19 patients recommend dexamethasone or other alternative corticosteroids, including methylprednisolone, hydrocortisone, or prednisone, as a treatment choice for severely ill COVID-19 patients. This review will discuss the pharmacology, mechanism of action, pharmacodynamics, pharmacokinetics, and benefits of corticosteroids in COVID-19 patients, and review current published clinical evidence on corticosteroids. Keywords: Corticosteroids, COVID-19, ARDS
{"title":"Calming the Storm: A review of corticosteroid use in severely ill COVID-19 patients on mechanical ventilation","authors":"T. Dinh, Cherie Chu","doi":"10.53097/jmv.10036","DOIUrl":"https://doi.org/10.53097/jmv.10036","url":null,"abstract":"The importance of corticosteroids in the therapy of COVID-19 has been controversial. However, as the world develops a better understanding regarding the pathophysiology of COVID-19, we are realizing that suppressing the host immune response may reduce lung inflammation preventing further complications. In addition, more high-quality randomized controlled trials, meta-analysis, and review articles are being published discussing the role of corticosteroids. Majority of these studies concluded that corticosteroids are beneficial for hospitalized severely ill COVID-19 patients requiring supplemental oxygen. To date, therapeutic guidelines for COVID-19 patients recommend dexamethasone or other alternative corticosteroids, including methylprednisolone, hydrocortisone, or prednisone, as a treatment choice for severely ill COVID-19 patients. This review will discuss the pharmacology, mechanism of action, pharmacodynamics, pharmacokinetics, and benefits of corticosteroids in COVID-19 patients, and review current published clinical evidence on corticosteroids. Keywords: Corticosteroids, COVID-19, ARDS","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48377687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Review of the most common terms used in mechanical ventilation and their definitions.
回顾机械通风中最常用的术语及其定义。
{"title":"Glossary and definitions of terms used in mechanical ventilation","authors":"R. Chatburn","doi":"10.53097/jmv.10030","DOIUrl":"https://doi.org/10.53097/jmv.10030","url":null,"abstract":"Review of the most common terms used in mechanical ventilation and their definitions.","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46616111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monitoring the exhaled caron dioxide pressure, known as end-tidal CO2 (ETCO2) has become the standard of care during anesthesia, intensive care units, and during cardiac arrest resuscitation. However, volumetric capnometry provides much more useful information other than the ETCO2.
{"title":"Volumetric Capnometry, more than end-tidal carbon dioxide","authors":"Mia Shokry, Kimiyo H. Yamasaki","doi":"10.53097/jmv.10032","DOIUrl":"https://doi.org/10.53097/jmv.10032","url":null,"abstract":"Monitoring the exhaled caron dioxide pressure, known as end-tidal CO2 (ETCO2) has become the standard of care during anesthesia, intensive care units, and during cardiac arrest resuscitation. However, volumetric capnometry provides much more useful information other than the ETCO2.","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44820862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adaptive Support Ventilation (ASV) is a fully closed loop ventilation where the operator input the desired PEEP, FiO2 and the target minute ventilation (MV) expressed as a percentage according to ideal body weight. The ventilator selects the target respiratory pattern (tidal volume, respiratory rate, and inspiratory time) based on the observed respiratory mechanics. However, there are no published guidelines on settings and adjusting the target MV in different disease states during ASV ventilation. INTELLiVENT-ASV, is the new generation modified algorithm of ASV, has made this issue much easier and simpler as the operator inputs a desired range of the end tidal exhaled carbon dioxide, and oxygen saturation and the algorithm will adjust the minute ventilation percentage as well as PEEP and FiO2 automatically to stay within that range. In this article we describe some evidence-based guidelines on how to set and adjust the target MV in various clinical conditions. Keywords: ASV, INTELLiVENT-ASV, Closed loop ventilation, End tidal CO2, ARDS, COPD, Respiratory failure
{"title":"Guidelines on setting the target minute ventilation in Adaptive Support Ventilation","authors":"J. Arnal, Ehab Daoud","doi":"10.53097/jmv.10029","DOIUrl":"https://doi.org/10.53097/jmv.10029","url":null,"abstract":"Adaptive Support Ventilation (ASV) is a fully closed loop ventilation where the operator input the desired PEEP, FiO2 and the target minute ventilation (MV) expressed as a percentage according to ideal body weight. The ventilator selects the target respiratory pattern (tidal volume, respiratory rate, and inspiratory time) based on the observed respiratory mechanics. However, there are no published guidelines on settings and adjusting the target MV in different disease states during ASV ventilation. INTELLiVENT-ASV, is the new generation modified algorithm of ASV, has made this issue much easier and simpler as the operator inputs a desired range of the end tidal exhaled carbon dioxide, and oxygen saturation and the algorithm will adjust the minute ventilation percentage as well as PEEP and FiO2 automatically to stay within that range. In this article we describe some evidence-based guidelines on how to set and adjust the target MV in various clinical conditions. Keywords: ASV, INTELLiVENT-ASV, Closed loop ventilation, End tidal CO2, ARDS, COPD, Respiratory failure","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42536058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Four Truths 1. The truth of confusion 2. The truth of the origin of confusion 3. The truth of the cessation of confusion 4. The truth of the path leading to the cessation of confusion The 10-Fold Path 1. A breath is one cycle of positive flow (inspiration) and negative flow (expiration) defined in terms of the flow-time curve. 2. A breath is assisted if the ventilator does work on the patient. 3. A ventilator assists breathing using either pressure control or volume control based on the equation of motion for the respiratory system. 4. Breaths are classified by the criteria that trigger (start) and cycle (stop) inspiration 5. Trigger and cycle events can be initiated by the patient or the machine. 6. Breaths are classified as spontaneous or mandatory based on both the trigger and cycle events. 7. There are 3 breath sequences: Continuous mandatory ventilation (CMV), Intermittent Mandatory Ventilation (IMV), and Continuous Spontaneous Ventilation (CSV). 8. There are 5 basic ventilatory patterns: VC-CMV, VC-IMV, PC-CMV, PC-IMV, and PC-CSV: 9. Within each ventilatory pattern there are several variations that can be distinguished by their targeting scheme(s). 10. A mode of ventilation is classified according to its control variable, breath sequence, and targeting scheme(s). Keywords: Breath. Trigger, Cycle, Breath sequences, Ventilatory patterns, Mode of ventilation
{"title":"Four Truths of Mechanical Ventilation and the Ten-Fold Path to Enlightenment","authors":"R. Chatburn","doi":"10.53097/jmv.10028","DOIUrl":"https://doi.org/10.53097/jmv.10028","url":null,"abstract":"The Four Truths 1. The truth of confusion 2. The truth of the origin of confusion 3. The truth of the cessation of confusion 4. The truth of the path leading to the cessation of confusion The 10-Fold Path 1. A breath is one cycle of positive flow (inspiration) and negative flow (expiration) defined in terms of the flow-time curve. 2. A breath is assisted if the ventilator does work on the patient. 3. A ventilator assists breathing using either pressure control or volume control based on the equation of motion for the respiratory system. 4. Breaths are classified by the criteria that trigger (start) and cycle (stop) inspiration 5. Trigger and cycle events can be initiated by the patient or the machine. 6. Breaths are classified as spontaneous or mandatory based on both the trigger and cycle events. 7. There are 3 breath sequences: Continuous mandatory ventilation (CMV), Intermittent Mandatory Ventilation (IMV), and Continuous Spontaneous Ventilation (CSV). 8. There are 5 basic ventilatory patterns: VC-CMV, VC-IMV, PC-CMV, PC-IMV, and PC-CSV: 9. Within each ventilatory pattern there are several variations that can be distinguished by their targeting scheme(s). 10. A mode of ventilation is classified according to its control variable, breath sequence, and targeting scheme(s). Keywords: Breath. Trigger, Cycle, Breath sequences, Ventilatory patterns, Mode of ventilation","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45365854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ehab Daoud, Kimiyo H. Yamasaki, Ronald Sanderson, Mia Shokry
Abstract: Background There has been an exponential increase in modes of mechanical ventilation over the last couple decades. With this increase, there have been paucity of evidence of which mode is superior to others or much guidance to use a mode in different disease status causing respiratory failure. Methods: An international survey of six questions was posted on the “society of mechanical ventilation” website and advertised on social media over the period of four months. This is a descriptive study, results are presented in two different ways. First as the total modes used and secondly, per the geographical areas as the preferred mode, mode used mostly in ARDS, COPD, and Spontaneous weaning trials. Results: Conventional older modes, Volume-controlled and Pressure-controlled ventilation were used significantly more in general and in different disease states irrespective of geographical location. Four other modes were used almost equally in all disease states irrespective of geographical location. Pressure support ventilation was the most common mode used during the spontaneous breathing trial. Conclusion: There was large heterogenicity of modes used between clinicians in general, in different disease states and in between different international geographical locations. Mechanical ventilation modes utilization varies widely and remains a personal preference with no consensus between clinicians globally. Keywords: Modes of mechanical ventilation, ARDS, COPD, SBT, survey
{"title":"Mechanical ventilation modes utilization. An international survey of clinicians","authors":"Ehab Daoud, Kimiyo H. Yamasaki, Ronald Sanderson, Mia Shokry","doi":"10.53097/jmv.10031","DOIUrl":"https://doi.org/10.53097/jmv.10031","url":null,"abstract":"Abstract: Background There has been an exponential increase in modes of mechanical ventilation over the last couple decades. With this increase, there have been paucity of evidence of which mode is superior to others or much guidance to use a mode in different disease status causing respiratory failure. Methods: An international survey of six questions was posted on the “society of mechanical ventilation” website and advertised on social media over the period of four months. This is a descriptive study, results are presented in two different ways. First as the total modes used and secondly, per the geographical areas as the preferred mode, mode used mostly in ARDS, COPD, and Spontaneous weaning trials. Results: Conventional older modes, Volume-controlled and Pressure-controlled ventilation were used significantly more in general and in different disease states irrespective of geographical location. Four other modes were used almost equally in all disease states irrespective of geographical location. Pressure support ventilation was the most common mode used during the spontaneous breathing trial. Conclusion: There was large heterogenicity of modes used between clinicians in general, in different disease states and in between different international geographical locations. Mechanical ventilation modes utilization varies widely and remains a personal preference with no consensus between clinicians globally. Keywords: Modes of mechanical ventilation, ARDS, COPD, SBT, survey","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42353275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Non-invasive ventilation use in acute COPD exacerbation and acute respiratory failure is very strong, however the evidence beyond home non-invasive ventilation for COPD patients is less clear. In this review we summarize the literature on the effectiveness of home non-invasive ventilation on mortality, hospital admission rates, quality of life, lung functions, gas exchange, exercise tolerance as well as mood and anxiety. Published guidelines from multiple societies mostly give weak and conditional guidelines on the use of home non-invasive ventilation. High intensity home non-invasive ventilation was recently introduced and may further improve the outcomes. New research regarding high intensity home non-invasive ventilation and new technology are needed to define the role and the benefits of home non-invasive ventilation in patients with COPD. Keywords: Home non-invasive ventilation, COPD, GOLD
{"title":"Home use of Non-invasive Ventilation for chronic obstructive pulmonary disease. Literature Review and Update.","authors":"Kimiyo H. Yamasaki","doi":"10.53097/jmv.10023","DOIUrl":"https://doi.org/10.53097/jmv.10023","url":null,"abstract":"Non-invasive ventilation use in acute COPD exacerbation and acute respiratory failure is very strong, however the evidence beyond home non-invasive ventilation for COPD patients is less clear. In this review we summarize the literature on the effectiveness of home non-invasive ventilation on mortality, hospital admission rates, quality of life, lung functions, gas exchange, exercise tolerance as well as mood and anxiety. Published guidelines from multiple societies mostly give weak and conditional guidelines on the use of home non-invasive ventilation. High intensity home non-invasive ventilation was recently introduced and may further improve the outcomes. New research regarding high intensity home non-invasive ventilation and new technology are needed to define the role and the benefits of home non-invasive ventilation in patients with COPD. Keywords: Home non-invasive ventilation, COPD, GOLD","PeriodicalId":73813,"journal":{"name":"Journal of mechanical ventilation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42495017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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