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Calculating the work of breathing during mechanical ventilation. 机械通气时呼吸功的计算。
Pub Date : 2021-06-01 DOI: 10.53097/jmv.10025
Mia Shokry, Melina Simonpietri, Kimiyo H. Yamasaki
Left figure: Passive patient esophageal pressure (Pes) in cmH2O on x-axis versus tidal volume in ml on y-axis. Green dashed line represents the chest wall compliance Right figure: same patient actively breathing on pressure support ventilation. (Pes) in cmH2O on x-axis versus tidal volume in ml on y-axis. Green dashed line represents the chest wall compliance. Red shaded area is the Campbell diagram representing the inspiratory work of breathing
左图:x轴为被动患者食管压(Pes) (cmH2O)与y轴为潮汐容积(ml)。绿色虚线表示胸壁顺应性右图:同一患者在压力支持通气下主动呼吸。(Pes)在x轴上cmH2O与潮汐体积在y轴上ml。绿色虚线表示胸壁顺应性。红色阴影区域是坎贝尔图,代表呼吸的吸气作用
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引用次数: 0
Automated mechanical ventilation using Adaptive Support Ventilation versus conventional ventilation including ventilator length of stay, mortality, and professional social aspects of adoption of new technology. 使用自适应支持通气与传统通气的自动机械通气,包括呼吸机停留时间、死亡率和采用新技术的专业社会方面。
Pub Date : 2021-06-01 DOI: 10.53097/jmv.10021
Ronald Sanderson, Denise Whitley, Christopher Batacan
Background Automation of mechanical ventilation allows for reduction of variation in patient management and has the potential to provide increased patient safety by strict adherence to computer driven ventilator protocols. Methods: A retrospective, observational study compared a group of 196 of general ICU patients managed exclusively on automated mechanical ventilation, adaptive support ventilation (ASV), to another group of 684 managed by usual, non-automated mechanical ventilation (No ASV). The data was collected in a unique access database designed to collect data for assessment of mechanical ventilation outcomes in a small medical center ICU. Results: The length of ventilator stay was non-significant between both groups, (81.7 ± 35.2 hours) in the ASV group; vs. (94.1 ± 35.1 hours) in the No ASV. Percent mortality was significantly less in the ASV group, 8.6% compared to 27.3% in the No ASV. Conclusion: Automated ventilation appears to be a safe ventilator strategy; however, cause effect relationships cannot be determined without further, more sophisticated studies. Keywords: Closed loop ventilation, ASV, Ventilator length of stay, Percent minute ventilation
背景:机械通气的自动化可以减少患者管理的变化,并有可能通过严格遵守计算机驱动的呼吸机协议来提高患者的安全性。方法:一项回顾性观察性研究比较了196名完全采用自动机械通气、适应性支持通气(ASV)治疗的普通ICU患者与684名采用常规非自动机械通气(无ASV)的患者。数据收集在一个独特的访问数据库中,该数据库旨在收集数据,用于评估小型医疗中心ICU的机械通气结果。结果:两组呼吸机停留时间无显著性差异,ASV组为(81.7±35.2小时);而无ASV组为(94.1±35.1小时)。ASV组的死亡率显著降低,为8.6%,而无ASV组为27.3%。结论:自动通气是一种安全的呼吸机策略;然而,如果没有更深入、更复杂的研究,就无法确定因果关系。关键词:闭环通气,ASV,呼吸机停留时间,分钟通气百分比
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引用次数: 0
Electrical Impedance Tomography: the future of mechanical ventilation? 电阻抗断层扫描:机械通气的未来?
Pub Date : 2021-06-01 DOI: 10.53097/jmv.10024
Melina Simonpietri, Mia Shokry, Ehab Daoud
Electrical Impedance Tomography is a rapidly evolving technology used for bedside lung imaging. Although EIT devices have been commercially available for the past decade, they are still not commonly used in everyday clinical practice. EIT has multiple benefits over standard chest imaging techniques; it is non-invasive, it can be used at bedside and it allows continuous monitoring of the patient’s condition. EIT can change the standard practice for monitoring lung function and caring for patients on mechanical ventilation. In this concise review, we will discuss the general concepts of EIT and its clinical applications. As this technology keeps developing and becomes more available for clinical use, it might revolutionize the way we practice mechanical ventilation. Additional studies need to be performed to compare its benefits to our current practice. Keywords: EIT, Mechanical ventilation, PEEP, Overdistention
电阻抗断层扫描是一项快速发展的技术,用于床边肺成像。尽管EIT设备在过去十年中已经商业化,但它们仍然不常用于日常临床实践。与标准的胸部成像技术相比,EIT具有多种优势;它是非侵入性的,可以在床边使用,并且可以持续监测病人的病情。EIT可以改变监测肺功能和护理机械通气患者的标准做法。在这篇简明的综述中,我们将讨论EIT的一般概念及其临床应用。随着这项技术的不断发展,越来越多的临床应用,它可能会彻底改变我们使用机械通气的方式。需要进行更多的研究来比较它与我们目前的做法的好处。关键词:EIT;机械通气;PEEP
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引用次数: 1
Review of mechanical ventilation for the non-critical care trained practitioner. Part 2 非重症监护培训从业者的机械通气回顾。第2部分
Pub Date : 2021-03-01 DOI: 10.53097/jmv.10016
Rebecca Shimabukuro Shimabukuro, Ehab Daoud
There have been a recent shortage of both critical care physicians and respiratory therapists with training in mechanical ventilation that is accentuated by the recent COVID-19 crisis. Hospitalists find themselves more often dealing with and treating critically ill patients on mechanical ventilation without specific training. The first part of this review attempted to explain and simplify some of the physiologic concepts and basics of mechanical ventilation. This second part of the review we will discuss some of the common modes used for support and weaning during mechanical ventilation and to address some of the adverse effects associated with mechanical ventilation. We understand the complexity of the subject and this review would not be a substitute of seeking appropriate counselling, further training, and medical knowledge about mechanical ventilation. Further free resources are available to help clinicians who feel uncomfortable making decisions with such technology Keywords: COPD, ARDS, Weaning, VCV, PCV, ASV, MMV, NAVA, PSV, ATC, VSV, PRVC, APRV
最近缺乏接受过机械通气培训的重症监护医生和呼吸治疗师,最近的新冠肺炎危机加剧了这一情况。住院医生发现自己更经常在没有经过专门训练的情况下使用机械通气来处理和治疗危重患者。本综述的第一部分试图解释和简化机械通气的一些生理概念和基础知识。在综述的第二部分,我们将讨论机械通气期间用于支持和断奶的一些常见模式,并解决与机械通气相关的一些不良影响。我们理解这一主题的复杂性,这次审查不能代替寻求适当的咨询、进一步的培训和机械通气的医学知识。更多的免费资源可用于帮助那些对使用此类技术做出决策感到不舒服的临床医生关键词:COPD、ARDS、断奶、VCV、PCV、ASV、MMV、NAVA、PSV、ATC、VSV、PRVC、APRV
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引用次数: 0
Respiratory and Gastrointestinal systems; friends or foes? 呼吸和胃肠系统;朋友还是敌人?
Pub Date : 2021-03-01 DOI: 10.53097/jmv.10018
Ehab Daoud
The article by Obeidat andRandhawain this issue “Gastrointestinal complications in critical care patients and effects of mechanical ventilation on the gastrointestinal tract”1is a great reminder of this important topicand a must read for ICU clinicians. The interaction between the gastro-intestinal system and the respiratory system is a tight yet not fully understoodcomplex one, and unfortunately gets overlooked.
Obeidat和Randhawain在本期发表的文章《重症监护患者的胃肠道并发症和机械通气对胃肠道的影响》1很好地提醒了人们这一重要话题,也是ICU临床医生必读的内容。胃肠系统和呼吸系统之间的相互作用是一个紧密但尚未完全理解的复杂系统,不幸的是,它被忽视了。
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引用次数: 0
Adaptive Support Ventilation (ASV). Beneficial or not? 自适应支持通风(ASV)。是否有益?
Pub Date : 2021-02-21 DOI: 10.53097/jmv.10026
Denise Wheatley, Krystal Young
Ventilators functions and features have evolved with the advancement of technology along with the addition of microprocessors. It is important to understand and examine the benefits and risks associated with these advanced automated modes. Adaptive Support Ventilation (ASV) is a mode that is unique to the Hamilton Medical ventilators, thereby limiting the number of clinicians who have experience with using this mode. ASV can make changes to respiratory rate and tidal volume and adjusting the driving pressure in the absence of a professional. ASV changes ventilator strategies when it detects changes to a patient’s lung dynamics. The scope of ASV mode is not universally understood. Respiratory therapists may feel their position would be threatened with the use of smart automated modes. This paper will aim to review the literature on the ASV mode of ventilation. The literature review will address the following research questions to broaden the understanding of the risks and benefits of the ASV mode. 1) Is the ASV mode effective for weaning patients? 2) Is ASV a safe mode of ventilation for patients with COPD and ARDS? 3) Is ASV a safe mode of ventilation with changes in lung dynamics? 4) Does ASV impact the bedside respiratory therapist? Conclusions: ASV appears to be at least effective or even more superior to other modes especially during weaning off mechanical ventilation, and in other forms of respiratory failure. More studies in different clinical conditions and head-to-head with other modes. Keywords: ASV, COPD, ARDS, Weaning
随着技术的进步以及微处理器的加入,通风机的功能和特点也在不断发展。了解和检查与这些高级自动化模式相关的好处和风险非常重要。自适应支持通气(ASV)是汉密尔顿医疗呼吸机独有的一种模式,因此限制了有使用该模式经验的临床医生的数量。ASV可以在没有专业人员的情况下改变呼吸频率和潮气量,并调整驾驶压力。ASV在检测到患者肺部动力学变化时会改变呼吸机策略。ASV模式的范围尚未得到普遍理解。呼吸治疗师可能会觉得,使用智能自动化模式会威胁到他们的地位。本文旨在回顾有关ASV通气模式的文献。文献综述将解决以下研究问题,以拓宽对ASV模式风险和收益的理解。1) ASV模式对断奶患者有效吗?2) ASV是COPD和ARDS患者的安全通气模式吗?3) ASV是一种安全的通气模式吗?4) ASV会影响床边呼吸治疗师吗?结论:ASV似乎至少比其他模式有效,甚至更优越,尤其是在脱离机械通气的情况下,以及在其他形式的呼吸衰竭中。在不同的临床条件下进行更多的研究,并与其他模式进行正面交锋。关键词:ASV、COPD、ARDS、断奶
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引用次数: 0
Gastrointestinal complications in critical care patients and effects of mechanical ventilation on the gastrointestinal tract 危重症患者胃肠道并发症及机械通气对胃肠道的影响
Pub Date : 2021-02-19 DOI: 10.53097/jmv.10017
Adham E Obeidat, Sandeep Randhawa
Patients in the intensive care unit (ICU) especially those who require mechanical ventilation are at increased risk for developing gastrointestinal (GI) complications such as bleeding, infection, and motility dysfunction. It is estimated that the prevalence of GI complications in those patients is approximately 50-80% and lots of those go undiagnosed. Complications can affect different parts of the GI system, including the esophagus, stomach, small intestine, large intestine, liver, and pancreas. Effects might include dysmotility, diarrhea, inflammation, infection, direct mucosal injuries, ulcerations, and bleeding, and it can be associated with high mortality rates. Moreover, it is believed that the GI tract has a significant contribution in the development of multiple organ dysfunction syndrome (MODS) in critically ill patients. Mechanical ventilation either alone or in association with other critical illness may have a multitude of effects on almost all the organs of the gastro-intestinal tract. Attention of those interaction and side effects can improve outcomes and potentially mortality. In this review, we describe the mechanisms proposed for mechanical ventilation induced GI complications and different GI complications which can affect the critically ill patient. Keywords: PEEP, Prone position, Dysmotility, GERD, GI bleeding, Ileus, Aspiration, Acalculous cholecystitis
重症监护病房(ICU)的患者,特别是那些需要机械通气的患者,发生胃肠道(GI)并发症(如出血、感染和运动功能障碍)的风险增加。据估计,这些患者的胃肠道并发症发生率约为50-80%,其中许多未被诊断出来。并发症可影响胃肠道系统的不同部位,包括食道、胃、小肠、大肠、肝脏和胰腺。其影响可能包括运动障碍、腹泻、炎症、感染、直接粘膜损伤、溃疡和出血,并可能与高死亡率相关。此外,人们认为胃肠道在危重患者多器官功能障碍综合征(MODS)的发展中起着重要作用。机械通气无论是单独使用还是与其他危重疾病联合使用,都可能对胃肠道的几乎所有器官产生多种影响。注意这些相互作用和副作用可以改善结果和潜在的死亡率。在这篇综述中,我们描述了机械通气引起的胃肠道并发症和不同的胃肠道并发症可能影响危重患者的机制。关键词:PEEP,俯卧位,运动障碍,GERD,消化道出血,肠梗阻,误吸,无结石性胆囊炎
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引用次数: 2
Airway Pressure Release Ventilation setting disagreements. A survey of clinicians 气道压力释放通气设置不一致。对临床医生的调查
Pub Date : 2020-12-01 DOI: 10.53097/JMV.10010
S. Randhawa, R. Sato, Ehab Daoud
Background: Airway pressure release ventilation has been available to clinicians for the last four decades. Unfortunately, its clinical value continues to be debatable. One of the many reasons responsible is the lack of consistency between its settings in clinical practice and research. We hypothesized that clinicians disagree on specific methods when establishing these parameters. Materials and Methods: A questionnaire-based survey was developed and sent to clinicians (critical care attending physician, critical care fellows in training and respiratory therapists) in about one hundred different academic hospitals with critical care training program. The survey consisted of ten questions including each of the four major APRV settings: T-High, T-Low, P-High, and P-Low. The survey was anonymous. Main results: Amongst the 187 respondents, there were significant disagreements between different categories of clinicians regarding methodology for establishing initial settings of APRV. However, when the responses were analyzed after sub-grouping based on categories of clinicians (Critical care attending physician vs critical care fellows vs respiratory therapists), no significant differences could be found. Conclusions: There is no agreement between different categories of clinicians when it comes to the methodology for establishing initial APRV settings. Our study highlights the need for larger clinical trials comparing different approaches to the same which could then be used for establishing scientific guidelines based on best evidence. Keywords: APRV, survey, T-High, T-Low, P-High, P-Low
背景:在过去的四十年里,临床医生可以使用气道压力释放通气。不幸的是,它的临床价值仍然存在争议。其中一个原因是其临床实践和研究环境之间缺乏一致性。我们假设临床医生在确定这些参数时对具体方法存在分歧。材料和方法:制定了一项基于问卷的调查,并将其发送给大约100家不同学术医院的临床医生(重症监护主治医师、接受培训的重症监护研究员和呼吸治疗师),这些医院都有重症监护培训计划。该调查由十个问题组成,包括四个主要APRV设置中的每一个:T-High、T-Low、P-High和P-Low。这项调查是匿名的。主要结果:在187名受访者中,不同类别的临床医生在建立APRV初始设置的方法上存在重大分歧。然而,当根据临床医生的类别(重症监护主治医师与重症监护研究员与呼吸治疗师)对分组后的反应进行分析时,没有发现显著差异。结论:不同类别的临床医生在建立初始APRV设置的方法上没有达成一致。我们的研究强调,需要进行更大规模的临床试验,将不同的方法与相同的方法进行比较,然后根据最佳证据制定科学指南。关键词:APRV,调查,T-高,T-低,P-高,P-低
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引用次数: 0
Mechanical ventilation for the non-critical care trained practitioner. Part 1 为非重症监护培训的从业者提供机械通气。第1部分
Pub Date : 2020-12-01 DOI: 10.53097/JMV.10011
Ehab Daoud, Rebecca Shimabukuro Shimabukuro
There have been a recent shortage of both critical care physicians and respiratory therapists with training in mechanical ventilation that is accentuated by the recent COVID-19 crisis. Hospitalists and primary care physicians find themselves more often dealing with and treating critically ill patients on mechanical ventilation without specific training. This two part review will try to explain and simplify some of the physiologic concepts of mechanical ventilation, strategies for managements of different diseases, monitoring, brief review of some of the common modes used for support and weaning during mechanical ventilation and to address some of the adverse effects associated with mechanical ventilation. We understand the complexity of the subject and this review would not be a substitute of seeking appropriate counselling, further training, and medical knowledge about mechanical ventilation. Further free resources are available to help clinicians who feel uncomfortable making decisions with such technology Keywords: Mechanical ventilation, Driving pressure, Compliance, Resistance, Capnometry, Dead space, ARDS, PEEP, auto-PEEP, Plateau pressure, esophageal balloon
最近缺乏接受过机械通气培训的重症监护医生和呼吸治疗师,最近的新冠肺炎危机加剧了这一情况。住院医生和初级保健医生发现自己更经常在没有经过专门培训的情况下使用机械通气来处理和治疗危重患者。这篇由两部分组成的综述将试图解释和简化机械通气的一些生理概念、不同疾病的管理策略、监测、机械通气期间用于支持和断奶的一些常见模式的简要综述,并解决与机械通气相关的一些不良影响。我们理解这一主题的复杂性,这次审查不能代替寻求适当的咨询、进一步的培训和机械通气的医学知识。更多的免费资源可用于帮助那些对使用此类技术感到不舒服的临床医生做出决定关键词:机械通气、驱动压力、顺应性、阻力、Capnometry、死区、ARDS、PEEP、自动PEEP、高原压力、食道球囊
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引用次数: 1
Accurate measurement of ventilator length of stay and ventilator days for use in assessing patient safety and ventilator associated events. 准确测量呼吸机停留时间和呼吸机天数,用于评估患者安全性和呼吸机相关事件。
Pub Date : 2020-12-01 DOI: 10.53097/JMV.10009
Kimiyo H. Yamasaki, J. Mullen, Denise Wheatley, Ron R Sanderson
Objective: Accurate measurements of ventilator length of stay are important for quality measures and mandated by Centers of Disease Control for reporting ventilator associated events. However, it is unknown which method of such a calculation gives the more accurate results. Design: We collected data using three different methods of calculating ventilator length of stay in a community hospital ICU. The first method is the walk-through method for collection of data at 6 am, the second is a data base collection system we created where data was collected by respiratory therapists in a daily ventilator patient log then entered into the database, and finally from query of medical charges for ventilator days from financial department Results: There was statistically significant disagreement between the three methods. The walk though method and data base were not statistically different, but the data from financial charges overestimated the ventilator length of stay. Additionally, there was not statistically significant differences between the time of the walk-through data collection. Conclusion: Ventilator days and hours should be measured by a precise database rather than indirect methods of estimation like walk-through or financial charges. Patient exposure to risk, and reporting of ventilator time, whether days or hours should be measured directly, not estimated. A larger study needs to be performed to examine this variation in a broader medical setting. Keywords: ventilator length of stay, ventilator associated events, ventilator associated pneumonia
目的:呼吸机停留时间的准确测量对质量测量很重要,疾病控制中心要求报告呼吸机相关事件。然而,目前尚不清楚哪种计算方法能给出更准确的结果。设计:我们使用三种不同的计算呼吸机在社区医院ICU住院时间的方法收集数据。第一种方法是在早上6点进行数据收集的walk-through方法,第二种方法是我们创建的数据库收集系统,由呼吸治疗师在每日呼吸机患者日志中收集数据,然后输入数据库,最后从财务部门查询呼吸机天数的医疗费用。结果:三种方法之间存在统计学上的差异。行走方法和数据库差异无统计学意义,但财务收费数据高估了呼吸机停留时间。此外,在演练数据收集的时间之间没有统计学上的显著差异。结论:呼吸机天数和小时应通过精确的数据库进行测量,而不应采用预诊或财务收费等间接估算方法。患者暴露于风险和报告呼吸机时间,无论是天数还是小时,应直接测量,而不是估计。需要进行更大规模的研究,以在更广泛的医疗环境中检查这种差异。关键词:呼吸机住院时间,呼吸机相关事件,呼吸机相关肺炎
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引用次数: 0
期刊
Journal of mechanical ventilation
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