首页 > 最新文献

Journal of substance use and addiction treatment最新文献

英文 中文
Healthcare usage and cost-effectiveness of approach bias modification at 12-months for patients undergoing inpatient withdrawal for alcohol use disorder 酒精使用障碍住院戒断患者12个月时的医疗保健使用和方法偏倚修正的成本效益
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-11-24 DOI: 10.1016/j.josat.2025.209834
Nicola Huxley , Joshua B.B. Garfield , Anthony Harris , Petra K. Staiger , Dan I. Lubman , Victoria Manning

Introduction

There is evidence that approach bias modification (ApBM), a type of computerised cognitive training delivered during inpatient alcohol withdrawal treatment, significantly reduces relapse rate. Our analysis examines, for the first time, whether ApBM is cost-effective compared to sham-trained controls.

Methods

Patients at four inpatient withdrawal units were randomized to four daily sessions of ApBM, or sham (control) training. Self-reported data on alcohol use, treatment, and healthcare use was collected over 12-months. We conducted a trial-based cost-effectiveness study of ApBM (versus no ApBM) from a health system perspective. Costs were from relevant Australian 2022 sources. We estimated incremental differences between groups in healthcare costs and abstinence rates using mixed generalised linear models.

Results

At 12 months after discharge from the index withdrawal treatment episode, two thirds of participants had accessed acute health care services (i.e., inpatient withdrawal, ambulance, emergency department and hospital inpatient). Results generally indicated non-significant increases in cumulative costs ($6747, 95%CI: -$7743, $21,237; p = .361) at 12 months for the ApBM group versus controls. The incremental cost of ApBM versus no intervention for 12 months of continuous abstinence was $201,610, with confidence limits ranging from ApBM being less costly and more effective to more costly and less effective than no ApBM.

Conclusion

Although there was evidence of improved abstinence rates in the first 3-months post-discharge, delivering ApBM during acute alcohol withdrawal treatment will not likely generate net benefits over a 1-year period at any willingness-to-pay threshold, due to the continued heavy use of healthcare services in this population. Future research should test whether additional ApBM delivered post-discharge (e.g., via smartphone apps) could extend its relapse prevention effects and ultimately result in cost savings in the long-term.
有证据表明,在住院患者戒酒治疗期间提供的一种计算机化认知训练,即方法偏差修正(ApBM),可显著降低复发率。我们的分析首次检验了ApBM与假训练对照相比是否具有成本效益。方法4个住院停药单元的患者被随机分为4个ApBM训练组或假(对照)训练组。在12个月内收集了有关酒精使用、治疗和医疗保健使用的自我报告数据。我们从卫生系统的角度进行了一项基于试验的ApBM(与无ApBM相比)的成本效益研究。费用来自澳大利亚2022年的相关来源。我们使用混合广义线性模型估计各组之间在医疗费用和戒断率方面的增量差异。结果在指数戒断治疗发作结束12个月后,三分之二的参与者获得了急性卫生保健服务(即住院戒断、救护车、急诊科和住院)。结果普遍表明,与对照组相比,ApBM组在12个月时的累积成本无显著增加(6747美元,95%CI: - 7743美元,21,237美元;p = .361)。在12个月的持续戒断中,ApBM与不干预相比的增量成本为201,610美元,置信限范围从ApBM成本更低、更有效到ApBM成本更高、效果更差。结论:尽管有证据表明,在出院后的前3个月,戒断率有所提高,但由于该人群持续大量使用医疗服务,在急性酒精戒断治疗期间,在任何支付意愿阈值下,提供ApBM不太可能在1年内产生净收益。未来的研究应该测试在出院后提供额外的ApBM(例如,通过智能手机应用程序)是否可以延长其复发预防效果,并最终在长期内节省成本。
{"title":"Healthcare usage and cost-effectiveness of approach bias modification at 12-months for patients undergoing inpatient withdrawal for alcohol use disorder","authors":"Nicola Huxley ,&nbsp;Joshua B.B. Garfield ,&nbsp;Anthony Harris ,&nbsp;Petra K. Staiger ,&nbsp;Dan I. Lubman ,&nbsp;Victoria Manning","doi":"10.1016/j.josat.2025.209834","DOIUrl":"10.1016/j.josat.2025.209834","url":null,"abstract":"<div><h3>Introduction</h3><div>There is evidence that approach bias modification (ApBM), a type of computerised cognitive training delivered during inpatient alcohol withdrawal treatment, significantly reduces relapse rate. Our analysis examines, for the first time, whether ApBM is cost-effective compared to sham-trained controls.</div></div><div><h3>Methods</h3><div>Patients at four inpatient withdrawal units were randomized to four daily sessions of ApBM, or sham (control) training. Self-reported data on alcohol use, treatment, and healthcare use was collected over 12-months. We conducted a trial-based cost-effectiveness study of ApBM (versus no ApBM) from a health system perspective. Costs were from relevant Australian 2022 sources. We estimated incremental differences between groups in healthcare costs and abstinence rates using mixed generalised linear models.</div></div><div><h3>Results</h3><div>At 12 months after discharge from the index withdrawal treatment episode, two thirds of participants had accessed acute health care services (i.e., inpatient withdrawal, ambulance, emergency department and hospital inpatient). Results generally indicated non-significant increases in cumulative costs ($6747, 95%CI: -$7743, $21,237; <em>p</em> = .361) at 12 months for the ApBM group versus controls. The incremental cost of ApBM versus no intervention for 12 months of continuous abstinence was $201,610, with confidence limits ranging from ApBM being less costly and more effective to more costly and less effective than no ApBM.</div></div><div><h3>Conclusion</h3><div>Although there was evidence of improved abstinence rates in the first 3-months post-discharge, delivering ApBM during acute alcohol withdrawal treatment will not likely generate net benefits over a 1-year period at any willingness-to-pay threshold, due to the continued heavy use of healthcare services in this population. Future research should test whether additional ApBM delivered post-discharge (e.g., via smartphone apps) could extend its relapse prevention effects and ultimately result in cost savings in the long-term.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"181 ","pages":"Article 209834"},"PeriodicalIF":1.9,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A qualitative study investigating the role of humor in supporting recovery from addiction 一项质性研究调查幽默在支持成瘾恢复中的作用。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-11-24 DOI: 10.1016/j.josat.2025.209833
Samuel W. Stull , M. Elaine Wakely , Elizabeth C. Saunders , Nicholas C. Jacobson , Lisa A. Marsch , Stephanie T. Lanza

Introduction

Humor can be utilized in adaptive ways (i.e., humor used to reframe negative events) to support mental health. Humor-based interventions can improve mental health, but minimal research exists on humor in people with addiction. We sought to examine whether and how people in recovery from opioid addiction utilize humor in their daily lives and whether they perceive it as supportive of recovery.

Methods

Qualitative semi-structured interviews were conducted in one study visit with people in recovery from opioid addiction receiving methadone (n = 11). Extant literature and a reflexive thematic approach informed theme generation and coding; codes were developed inductively and deductively using thematic analysis.

Results

Participants had been in recovery for up to two years. Humor was central in most participants' lives, but its role varied considerably. We identified the following themes: Dark Humor and Lived Experience (humor used to make light of a difficult past); For Humor, Timing is Everything (dynamic receptivity to humor); Good Vibrations or Distractions? (pleasurable and distracting qualities of humor); and Read the Room: Social Contexts Can Drive the Supportive Role of Humor (humor to facilitate social connections and conversations about addiction). Most participants expressed enthusiasm for humor therapy, but preferences about the type of humor and setting varied.

Conclusion

Humor was integral to participant's lives. Greater investigation is needed into how recovery identity may interplay with preference for substance-use-related humor, whether humor can lead to sustainable mood improvements, and heterogeneity in preferred timing and context for humor.
引言:幽默可以以适应性的方式被利用(例如,幽默被用来重新定义负面事件)来支持心理健康。以幽默为基础的干预可以改善心理健康,但关于幽默对成瘾者的影响的研究很少。我们试图研究从阿片类药物成瘾中康复的人是否以及如何在日常生活中利用幽默,以及他们是否认为幽默有助于康复。方法:对接受美沙酮治疗的阿片类药物成瘾康复者进行定性半结构化访谈( = 11)。现有文献和反身性主题方法为主题生成和编码提供了信息;使用主题分析,归纳和演绎了代码。结果:参与者的康复期长达两年。幽默是大多数参与者生活的中心,但它的作用差别很大。我们确定了以下主题:黑色幽默和生活经验(幽默用来轻松过去的困难);对于幽默来说,时机就是一切(对幽默的动态接受能力);好的震动还是干扰?(幽默令人愉悦和分散注意力的特性);阅读房间:社会环境可以推动幽默的支持作用(幽默促进社会联系和关于成瘾的对话)。大多数参与者表达了对幽默疗法的热情,但对幽默类型和环境的偏好各不相同。结论:幽默是参与者生活中不可或缺的一部分。需要更多的调查来研究恢复身份如何与对物质使用相关幽默的偏好相互作用,幽默是否能导致持续的情绪改善,以及偏好幽默的时间和背景的异质性。
{"title":"A qualitative study investigating the role of humor in supporting recovery from addiction","authors":"Samuel W. Stull ,&nbsp;M. Elaine Wakely ,&nbsp;Elizabeth C. Saunders ,&nbsp;Nicholas C. Jacobson ,&nbsp;Lisa A. Marsch ,&nbsp;Stephanie T. Lanza","doi":"10.1016/j.josat.2025.209833","DOIUrl":"10.1016/j.josat.2025.209833","url":null,"abstract":"<div><h3>Introduction</h3><div>Humor can be utilized in adaptive ways (i.e., humor used to reframe negative events) to support mental health. Humor-based interventions can improve mental health, but minimal research exists on humor in people with addiction. We sought to examine whether and how people in recovery from opioid addiction utilize humor in their daily lives and whether they perceive it as supportive of recovery.</div></div><div><h3>Methods</h3><div>Qualitative semi-structured interviews were conducted in one study visit with people in recovery from opioid addiction receiving methadone (<em>n</em> = 11). Extant literature and a reflexive thematic approach informed theme generation and coding; codes were developed inductively and deductively using thematic analysis.</div></div><div><h3>Results</h3><div>Participants had been in recovery for up to two years. Humor was central in most participants' lives, but its role varied considerably. We identified the following themes: <em>Dark Humor and Lived Experience</em> (humor used to make light of a difficult past); <em>For Humor, Timing is Everything</em> (dynamic receptivity to humor); <em>Good Vibrations or Distractions?</em> (pleasurable and distracting qualities of humor); and <em>Read the Room: Social Contexts Can Drive the Supportive Role of Humor</em> (humor to facilitate social connections and conversations about addiction). Most participants expressed enthusiasm for humor therapy, but preferences about the type of humor and setting varied.</div></div><div><h3>Conclusion</h3><div>Humor was integral to participant's lives. Greater investigation is needed into how recovery identity may interplay with preference for substance-use-related humor, whether humor can lead to sustainable mood improvements, and heterogeneity in preferred timing and context for humor.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"181 ","pages":"Article 209833"},"PeriodicalIF":1.9,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retention among Medicaid beneficiaries in opioid treatment programs in California 保留加州阿片类药物治疗项目的医疗补助受益人。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-11-21 DOI: 10.1016/j.josat.2025.209837
William N. Dowd , Daniel H. Barch , Tami L. Mark , Chelsea Katz , Barrett W. Montgomery , Dylan DeLisle , Thanh T. Lu , Gary A. Zarkin

Background

Continuing medications for opioid use disorders (MOUD) for an extended period is important to achieve good outcomes, but many patients do not remain in treatment for even six months. The goal of this study was to develop and describe case-mix adjusted retention rates among California Opioid Treatment Programs (OTP).

Methods

We developed measures of 30-, 90-, and 180-day retention using data from the California Outcomes Management System for Medicaid beneficiaries admitted as an outpatient to an OTP between July 1, 2021 and June 30, 2022. We applied case-mix adjustment to the measures to ascertain whether differences in patient characteristics drive differences in OTP-level retention rates and assessed the proportion of total variance in retention rates attributable to differences between OTPs. Finally, we identified statistically underperforming and overperforming OTPs relative to expected retention based on case-mix and described the potential impact of improvement among underperforming OTPs on overall retention rates.

Results

The average case-mix adjusted OTP-level retention rate (N = 131 OTPs) at 30 days was 76 % (range: 45 %–99 %), at 90 days was 54 % (range: 32 %–91 %), and at 180 days was 40 % (range: 8 %–85 %); only 18 % of OTPs retained at least half of their patients for at least 180 days. The distribution of case-mix adjusted and unadjusted measures was similar, indicating that variation in retention rates was explained by factors other than patient demographic and clinical baseline characteristics. Measures were shown to reliably indicate differences between OTPs across all retention periods, with between-OTP variance accounting for no less than 87 % of total variance in the median OTP. We showed that increasing retention among statistically underperforming OTPs to levels expected given their case-mix would result in an additional 4 %, 5 %, and 7 % of patients retained for 30, 90, and 180 days, respectively.

Conclusion

There is considerable room for improvement in retention. The wide range of retention rates at the OTP level after case-mix adjustment suggests that such improvements are attainable. Efforts should be made to support dissemination of successful strategies to improve retention among OTPs. Policymakers should explore opportunities to facilitate improvement, such as enacting quality reporting programs for OTPs.
背景:长期持续治疗阿片类药物使用障碍(mod)对于获得良好的结果很重要,但许多患者甚至不能坚持治疗6个月。本研究的目的是发展和描述加州阿片类药物治疗项目(OTP)的病例组合调整保留率。方法:我们使用来自加州结果管理系统的数据,对2021年7月1日至2022年6月30日期间作为门诊就诊的医疗补助受益人制定了30、90和180天保留率的测量方法。我们采用病例组合调整方法来确定患者特征的差异是否会导致otp水平留置率的差异,并评估otp差异导致的留置率总方差的比例。最后,我们根据案例组合确定了相对于预期保留率的统计上表现不佳和表现优异的otp,并描述了在表现不佳的otp中改进对总体保留率的潜在影响。结果:平均治疗调整OTP-level保留率(N = 131 otp)在30 天76 %(范围:45 % -99 %),在90 天54 %(范围:32 % -91 %),和180 天40 %(范围:-85  % %);只有18% %的OTPs保留了至少一半的患者至少180 天。调整后的病例组合和未调整的病例组合的分布相似,表明保留率的变化是由患者人口统计学和临床基线特征以外的因素解释的。测量显示可靠地显示了所有保留期OTP之间的差异,OTP之间的方差占OTP中位数总方差的不少于87 %。我们发现,在统计上表现不佳的otp中,将保留率提高到考虑到其病例组合的预期水平,将分别使4 %、5 %和7 %的患者保留30天、90天和180 天。结论:留用率有很大的提高空间。在病例组合调整后,外地工作计划一级的保留率差别很大,这表明这种改进是可以实现的。应作出努力,支持传播成功的战略,以改善海外服务提供者的保留率。政策制定者应探索促进改进的机会,例如为otp制定质量报告计划。
{"title":"Retention among Medicaid beneficiaries in opioid treatment programs in California","authors":"William N. Dowd ,&nbsp;Daniel H. Barch ,&nbsp;Tami L. Mark ,&nbsp;Chelsea Katz ,&nbsp;Barrett W. Montgomery ,&nbsp;Dylan DeLisle ,&nbsp;Thanh T. Lu ,&nbsp;Gary A. Zarkin","doi":"10.1016/j.josat.2025.209837","DOIUrl":"10.1016/j.josat.2025.209837","url":null,"abstract":"<div><h3>Background</h3><div>Continuing medications for opioid use disorders (MOUD) for an extended period is important to achieve good outcomes, but many patients do not remain in treatment for even six months. The goal of this study was to develop and describe case-mix adjusted retention rates among California Opioid Treatment Programs (OTP).</div></div><div><h3>Methods</h3><div>We developed measures of 30-, 90-, and 180-day retention using data from the California Outcomes Management System for Medicaid beneficiaries admitted as an outpatient to an OTP between July 1, 2021 and June 30, 2022. We applied case-mix adjustment to the measures to ascertain whether differences in patient characteristics drive differences in OTP-level retention rates and assessed the proportion of total variance in retention rates attributable to differences between OTPs. Finally, we identified statistically underperforming and overperforming OTPs relative to expected retention based on case-mix and described the potential impact of improvement among underperforming OTPs on overall retention rates.</div></div><div><h3>Results</h3><div>The average case-mix adjusted OTP-level retention rate (N = 131 OTPs) at 30 days was 76 % (range: 45 %–99 %), at 90 days was 54 % (range: 32 %–91 %), and at 180 days was 40 % (range: 8 %–85 %); only 18 % of OTPs retained at least half of their patients for at least 180 days. The distribution of case-mix adjusted and unadjusted measures was similar, indicating that variation in retention rates was explained by factors other than patient demographic and clinical baseline characteristics. Measures were shown to reliably indicate differences between OTPs across all retention periods, with between-OTP variance accounting for no less than 87 % of total variance in the median OTP. We showed that increasing retention among statistically underperforming OTPs to levels expected given their case-mix would result in an additional 4 %, 5 %, and 7 % of patients retained for 30, 90, and 180 days, respectively.</div></div><div><h3>Conclusion</h3><div>There is considerable room for improvement in retention. The wide range of retention rates at the OTP level after case-mix adjustment suggests that such improvements are attainable. Efforts should be made to support dissemination of successful strategies to improve retention among OTPs. Policymakers should explore opportunities to facilitate improvement, such as enacting quality reporting programs for OTPs.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"181 ","pages":"Article 209837"},"PeriodicalIF":1.9,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145590342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationships of patient risk profiles and receipt of specialty treatment with early, sustained, and stable cessation of heavy alcohol use across populations 患者风险概况和接受专科治疗与人群中早期、持续和稳定停止重度酒精使用的关系
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-11-20 DOI: 10.1016/j.josat.2025.209836
Vanessa A. Palzes , Felicia W. Chi , Constance Weisner , Andrea H. Kline-Simon , Derek D. Satre , Asma Asyyed , Stacy Sterling

Background

Identifying individual-level factors that predict cessation of heavy alcohol use would inform the prevention, intervention, and treatment of heavy alcohol use. This study examined whether and how patient risk profiles and specialty treatment predict early, sustained, and stable cessation of heavy alcohol use, and whether there are differences by patient characteristics.

Methods

This electronic health records-based cohort study included 128,471 adults with heavy alcohol use (exceeded national daily or weekly drinking limits) in an integrated healthcare system between 6/1/2013 and 12/31/2014. Cessation of heavy alcohol use was examined over 1-year (early), 5-year (sustained), and 7-year follow-ups (stable), through 6/30/2022. Latent class analysis identified five patient risk profiles differentiated by type of heavy alcohol use and levels of health risk behaviors and comorbidities. Associations of risk profiles, specialty addiction or psychiatry treatment, race and ethnicity with cessation outcomes were examined with logistic regression.

Results

Approximately 65.8 % of the sample had early cessation at 1-year. Compared with patients in the heavy daily drinking and fewer health risks profile (DAILY), patients in the heavy daily drinking and more health risks profile (DAILY-R) had higher odds of early cessation (aOR [95 % CI] = 1.28 [1.23, 1.33]), while patients in risk profiles with heavy weekly drinking and substance use and mental health disorders had lower odds of early cessation (aORs = 0.40 to 0.77). Specialty treatment (versus no treatment) was associated with higher odds of early cessation (1.27 [1.18, 1.35]), which varied by risk profile. Hispanic/Latino patients in the DAILY-R profile had lower odds of early cessation than their White counterparts (0.84 [0.76, 0.91]). At 5 and 7 years, 60.7 % and 88.0 % had sustained and stable cessation after achieving the prior cessation status, respectively. Results of sustained and stable cessation were largely consistent with those of early cessation, but interactions with race and ethnicity were non-significant.

Conclusions

Specialty treatment may be effective for most types of patients with varying levels of health risks, across populations. Findings suggest that Hispanic/Latino patients with heavy daily drinking and more health risks may need tailored interventions in primary care to support cessation of heavy alcohol use.
背景:确定预测重度酒精使用停止的个人水平因素将为重度酒精使用的预防、干预和治疗提供信息。本研究调查了患者风险概况和专科治疗是否以及如何预测早期、持续和稳定地停止大量饮酒,以及患者特征是否存在差异。方法:这项基于电子健康记录的队列研究纳入了2013年6月1日至2014年12月31日在综合医疗保健系统中重度饮酒(超过国家每日或每周饮酒限制)的128,471名成年人。通过1年(早期)、5年(持续)和7年(稳定)的随访,直到2022年6月30日,对重度酒精使用的停止进行了检查。潜在分类分析确定了5个患者的风险概况,这些风险概况根据重度酒精使用的类型和健康风险行为和合并症的水平来区分。风险概况、特殊成瘾或精神病学治疗、种族和民族与戒烟结果的关系用逻辑回归进行了检验。结果:大约65.8% %的样本在1年后早期戒烟。与每日重度饮酒且健康风险较低(daily)的患者相比,每日重度饮酒且健康风险较高(daily - r)的患者早期戒烟的几率较高(aOR[95 % CI] = 1.28[1.23,1.33]),而每周重度饮酒并有物质使用和精神健康障碍风险的患者早期戒烟的几率较低(aOR = 0.40 ~ 0.77)。特殊治疗(与不治疗相比)与更高的早期戒烟几率相关(1.27[1.18,1.35]),这因风险概况而异。在DAILY-R档案中,西班牙裔/拉丁裔患者的早期戒烟几率低于白人患者(0.84[0.76,0.91])。在5年和7年 时,分别有60.7% %和88.0% %的患者在达到先前戒烟状态后持续稳定戒烟。持续稳定戒烟的结果与早期戒烟的结果基本一致,但与种族和民族的相互作用不显著。结论:专科治疗可能对不同人群中具有不同健康风险的大多数类型的患者有效。研究结果表明,每天大量饮酒和更大健康风险的西班牙裔/拉丁裔患者可能需要在初级保健中进行量身定制的干预措施,以支持停止大量饮酒。
{"title":"Relationships of patient risk profiles and receipt of specialty treatment with early, sustained, and stable cessation of heavy alcohol use across populations","authors":"Vanessa A. Palzes ,&nbsp;Felicia W. Chi ,&nbsp;Constance Weisner ,&nbsp;Andrea H. Kline-Simon ,&nbsp;Derek D. Satre ,&nbsp;Asma Asyyed ,&nbsp;Stacy Sterling","doi":"10.1016/j.josat.2025.209836","DOIUrl":"10.1016/j.josat.2025.209836","url":null,"abstract":"<div><h3>Background</h3><div>Identifying individual-level factors that predict cessation of heavy alcohol use would inform the prevention, intervention, and treatment of heavy alcohol use. This study examined whether and how patient risk profiles and specialty treatment predict early, sustained, and stable cessation of heavy alcohol use, and whether there are differences by patient characteristics.</div></div><div><h3>Methods</h3><div>This electronic health records-based cohort study included 128,471 adults with heavy alcohol use (exceeded national daily or weekly drinking limits) in an integrated healthcare system between 6/1/2013 and 12/31/2014. Cessation of heavy alcohol use was examined over 1-year (early), 5-year (sustained), and 7-year follow-ups (stable), through 6/30/2022. Latent class analysis identified five patient risk profiles differentiated by type of heavy alcohol use and levels of health risk behaviors and comorbidities. Associations of risk profiles, specialty addiction or psychiatry treatment, race and ethnicity with cessation outcomes were examined with logistic regression.</div></div><div><h3>Results</h3><div>Approximately 65.8 % of the sample had early cessation at 1-year. Compared with patients in the heavy daily drinking and fewer health risks profile (DAILY), patients in the heavy daily drinking and more health risks profile (DAILY-R) had higher odds of early cessation (aOR [95 % CI] = 1.28 [1.23, 1.33]), while patients in risk profiles with heavy weekly drinking and substance use and mental health disorders had lower odds of early cessation (aORs = 0.40 to 0.77). Specialty treatment (versus no treatment) was associated with higher odds of early cessation (1.27 [1.18, 1.35]), which varied by risk profile. Hispanic/Latino patients in the DAILY-R profile had lower odds of early cessation than their White counterparts (0.84 [0.76, 0.91]). At 5 and 7 years, 60.7 % and 88.0 % had sustained and stable cessation after achieving the prior cessation status, respectively. Results of sustained and stable cessation were largely consistent with those of early cessation, but interactions with race and ethnicity were non-significant.</div></div><div><h3>Conclusions</h3><div>Specialty treatment may be effective for most types of patients with varying levels of health risks, across populations. Findings suggest that Hispanic/Latino patients with heavy daily drinking and more health risks may need tailored interventions in primary care to support cessation of heavy alcohol use.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"181 ","pages":"Article 209836"},"PeriodicalIF":1.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145582162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishing a public health surveillance system for the opioid crisis: The experience of the HEALing Communities Study 为阿片类药物危机建立公共卫生监测系统:康复社区研究的经验。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-11-07 DOI: 10.1016/j.josat.2025.209832
Bridget Freisthler , Daniel J. Feaster , Charles Knott , Marc LaRochelle , John McCarthy , Svetla Slavova , Sharon L. Walsh , Jennifer Villani

Introduction

Efforts to reduce opioid overdose deaths in the United States have been stymied by the lack of timely and standardized population-level data for local, state, and national levels. The U.S. has a strong national need for linking opioid and other drug overdose surveillance data to service utilization data for overdose prevention and treatment to inform resource allocation and response planning.

Methods

We provide insight on the challenges of identifying, obtaining, and harmonizing administrative outcome data across four states using the collective experience from the HEALing Communities Study to test a community-engaged, data-driven, population-level intervention to reduce opioid overdose deaths. We also discuss the opportunities that arose from those challenges, as well as the relationships across state agencies that were strengthened.

Results

Challenges experienced by the research sites on obtaining administrative outcome data included issues around who owned the data, what level of data access and use was allowed, and difficulties related to the timeliness of the data, ability to harmonize the data elements, and lack of demographic data available for stratification. Opportunities arose from these challenges whereby research sites developed new partnerships with state agencies (including a key governmental official in the state administration), provided an additional layer of quality control for these data, and facilitated democratizing data so local communities could access them.

Conclusions

The overall lessons show the importance of adapting to external changes and maintaining strong partnerships to pursue shared goals. The HCS serves as an exemplar of how local and state jurisdictions can create comprehensive data systems for monitoring and responding to the opioid overdose epidemic.
导言:由于缺乏及时和标准化的地方、州和国家层面的人口数据,美国减少阿片类药物过量死亡的努力受到了阻碍。美国有强烈的国家需求,将阿片类药物和其他药物过量监测数据与服务利用数据联系起来,以预防和治疗过量,为资源分配和应对计划提供信息。方法:我们利用来自愈合社区研究的集体经验,提供了关于识别、获取和协调四个州行政结果数据的挑战的见解,以测试社区参与、数据驱动、人口水平的干预措施,以减少阿片类药物过量死亡。我们还讨论了从这些挑战中产生的机遇,以及加强了国家机构之间的关系。结果:研究站点在获取行政结果数据方面遇到的挑战包括:谁拥有数据、允许访问和使用什么级别的数据、数据的及时性、协调数据元素的能力以及缺乏可用于分层的人口统计数据等问题。机遇来自这些挑战,研究站点与国家机构(包括国家行政部门的关键政府官员)建立了新的伙伴关系,为这些数据提供了额外的质量控制层,并促进了数据的民主化,以便当地社区可以访问它们。结论:总的经验教训表明,适应外部变化和保持强有力的伙伴关系以追求共同目标的重要性。HCS是地方和州司法管辖区如何创建监测和应对阿片类药物过量流行的综合数据系统的典范。
{"title":"Establishing a public health surveillance system for the opioid crisis: The experience of the HEALing Communities Study","authors":"Bridget Freisthler ,&nbsp;Daniel J. Feaster ,&nbsp;Charles Knott ,&nbsp;Marc LaRochelle ,&nbsp;John McCarthy ,&nbsp;Svetla Slavova ,&nbsp;Sharon L. Walsh ,&nbsp;Jennifer Villani","doi":"10.1016/j.josat.2025.209832","DOIUrl":"10.1016/j.josat.2025.209832","url":null,"abstract":"<div><h3>Introduction</h3><div>Efforts to reduce opioid overdose deaths in the United States have been stymied by the lack of timely and standardized population-level data for local, state, and national levels. The U.S. has a strong national need for linking opioid and other drug overdose surveillance data to service utilization data for overdose prevention and treatment to inform resource allocation and response planning.</div></div><div><h3>Methods</h3><div>We provide insight on the challenges of identifying, obtaining, and harmonizing administrative outcome data across four states using the collective experience from the HEALing Communities Study to test a community-engaged, data-driven, population-level intervention to reduce opioid overdose deaths. We also discuss the opportunities that arose from those challenges, as well as the relationships across state agencies that were strengthened.</div></div><div><h3>Results</h3><div>Challenges experienced by the research sites on obtaining administrative outcome data included issues around who owned the data, what level of data access and use was allowed, and difficulties related to the timeliness of the data, ability to harmonize the data elements, and lack of demographic data available for stratification. Opportunities arose from these challenges whereby research sites developed new partnerships with state agencies (including a key governmental official in the state administration), provided an additional layer of quality control for these data, and facilitated democratizing data so local communities could access them.</div></div><div><h3>Conclusions</h3><div>The overall lessons show the importance of adapting to external changes and maintaining strong partnerships to pursue shared goals. The HCS serves as an exemplar of how local and state jurisdictions can create comprehensive data systems for monitoring and responding to the opioid overdose epidemic.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"181 ","pages":"Article 209832"},"PeriodicalIF":1.9,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shattering the STIGMA: Talking openly about MOUD in 12-step recovery programs 粉碎耻辱:在12步康复计划中公开谈论MAT。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-11-03 DOI: 10.1016/j.josat.2025.209829
Steven Klein , Juan Franco , Adam Scioli
Despite overwhelming evidence supporting Medications for Opioid Use Disorder (MOUD) for substance use disorders (SUDs), stigma persists within recovery communities—particularly in some circles of Alcoholics Anonymous (AA) and Narcotics Anonymous (NA)—that view Medications as incompatible with sobriety. This perspective piece explores the tension between life-saving pharmacologic interventions such as MOUD and deeply held beliefs within 12-step fellowships. Through the lens of a clinically grounded, narrative-driven, and first-person perspective we examine the origins of this stigma, including the historical ambivalence toward psychiatric medication in AA's founding literature. We also examine contemporary NA literature especially as it relates to the term “clean.” While many 12-step programs have increasingly accepted medications like antidepressants, MOUD remains stigmatized despite its proven effectiveness in reducing cravings, relapse, and overdose deaths. We argue that this resistance—often reinforced by sponsors, literature, and group norms—places patients at risk and undermines recovery. We use our personal experience as physicians and people in long-term recovery to call for a renewed interpretation of fellowship principles that embrace evidence-based treatment and affirms each individual's path to recovery. True sobriety should not require choosing between medication and belonging.
尽管有压倒性的证据支持药物辅助治疗(MAT)对物质使用障碍(sud)的治疗,但在康复社区中,特别是在一些匿名戒酒会(AA)和匿名戒毒会(NA)的圈子里,耻辱感仍然存在,他们认为MAT与清醒是不相容的。这篇透视文章探讨了挽救生命的药物干预措施(如阿片类药物使用障碍(MOUDs))与12步奖学金中根深蒂固的信念之间的紧张关系。通过临床基础的镜头,叙述驱动,和第一人称的视角,我们检查了这种耻辱的起源,包括历史上对精神药物的矛盾心理在AA的创始文献。我们还研究了当代NA文献,特别是与“清洁”一词相关的文献。虽然许多12步疗法越来越多地接受了抗抑郁药等药物,但mod仍然被污名化,尽管它在减少渴望、复发和过量死亡方面已被证明有效。我们认为,这种阻力——经常被赞助商、文献和团体规范所强化——使患者处于危险之中,并破坏康复。我们利用我们作为医生和长期康复患者的个人经验,呼吁重新解释奖学金原则,包括循证治疗,并肯定每个人的康复之路。真正的清醒不应该要求在药物治疗和归属之间做出选择。
{"title":"Shattering the STIGMA: Talking openly about MOUD in 12-step recovery programs","authors":"Steven Klein ,&nbsp;Juan Franco ,&nbsp;Adam Scioli","doi":"10.1016/j.josat.2025.209829","DOIUrl":"10.1016/j.josat.2025.209829","url":null,"abstract":"<div><div>Despite overwhelming evidence supporting Medications for Opioid Use Disorder (MOUD) for substance use disorders (SUDs), stigma persists within recovery communities—particularly in some circles of Alcoholics Anonymous (AA) and Narcotics Anonymous (NA)—that view Medications as incompatible with sobriety. This perspective piece explores the tension between life-saving pharmacologic interventions such as MOUD and deeply held beliefs within 12-step fellowships. Through the lens of a clinically grounded, narrative-driven, and first-person perspective we examine the origins of this stigma, including the historical ambivalence toward psychiatric medication in AA's founding literature. We also examine contemporary NA literature especially as it relates to the term “clean.” While many 12-step programs have increasingly accepted medications like antidepressants, MOUD remains stigmatized despite its proven effectiveness in reducing cravings, relapse, and overdose deaths. We argue that this resistance—often reinforced by sponsors, literature, and group norms—places patients at risk and undermines recovery. We use our personal experience as physicians and people in long-term recovery to call for a renewed interpretation of fellowship principles that embrace evidence-based treatment and affirms each individual's path to recovery. True sobriety should not require choosing between medication and belonging.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"181 ","pages":"Article 209829"},"PeriodicalIF":1.9,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145454155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overdose Data to Action: A qualitative analysis of funded activities tailored for women. 从过量用药数据到行动:对为妇女量身定制的资助活动的定性分析。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-11-01 Epub Date: 2025-07-31 DOI: 10.1016/j.josat.2025.209768
Laura J Cremer, Ayana L Miles, Miranda E Gali, Nida Ali, Marissa Roberts, Minda Reed, Donjanea F Williams, Cherie R Rooks-Peck

Background: According to the Centers for Disease Control and Prevention (CDC), there was a 480 % increase in overdose deaths among all women from 1999 to 2021 (Jones et al., 2024). Women are uniquely impacted by substance use and overdose due to biological and cultural differences compared to men. CDC launched the Overdose Data to Action (OD2A) cooperative agreement in 2019 with the goal of helping to mitigate the opioid overdose crisis across the United States by supporting state and local health departments.

Methods: This study focused on a review of programmatic data submitted by OD2A jurisdictions that detail their prevention activities to identify how jurisdictions implemented activities to address the unique needs of women. The team conducted systematic content analysis using multiple rounds of coding.

Results: Most activities were tailored for pregnant women or women who had recently given birth and focused on expanding capacity to meet their needs. The most common activities were capacity-building activities to enhance efforts to address overdose needs for women (specifically pregnant women), resource development/sharing, and implementation/evaluation of best or promising practices for women.

Conclusion: While it is important that activities tailored for pregnant women continue, our study showed a gap in activities tailored to other populations of women where the problem may be the greatest, such as women who are incarcerated, women who engage in sex work, and other female sub-populations. To address overdose rates in women, future efforts would benefit from continuing activities for pregnant women but also attempting to reach other at-risk female populations.

背景:根据疾病控制和预防中心(CDC)的数据,从1999年到2021年,所有女性的过量死亡人数增加了480 % (Jones等人,2024年)。与男性相比,由于生理和文化差异,女性受到药物使用和过量使用的独特影响。疾病预防控制中心于2019年启动了“过量数据到行动”(OD2A)合作协议,目的是通过支持州和地方卫生部门,帮助缓解美国各地的阿片类药物过量危机。方法:本研究侧重于审查OD2A辖区提交的规划数据,这些数据详细说明了其预防活动,以确定辖区如何实施活动以满足妇女的独特需求。团队通过多轮编码进行了系统的内容分析。结果:大多数活动都是为孕妇或刚刚分娩的妇女量身定制的,重点是扩大满足她们需求的能力。最常见的活动是能力建设活动,以加强努力解决妇女(特别是孕妇)的过量用药需求,资源开发/共享,以及对妇女最佳或有前途的做法的实施/评价。结论:虽然为孕妇量身定制的活动继续进行很重要,但我们的研究表明,为问题可能最严重的其他妇女群体量身定制的活动存在差距,例如被监禁的妇女、从事性工作的妇女和其他女性亚群体。为了解决妇女用药过量的问题,今后的努力将受益于继续开展针对孕妇的活动,同时也将努力覆盖其他高危女性人群。
{"title":"Overdose Data to Action: A qualitative analysis of funded activities tailored for women.","authors":"Laura J Cremer, Ayana L Miles, Miranda E Gali, Nida Ali, Marissa Roberts, Minda Reed, Donjanea F Williams, Cherie R Rooks-Peck","doi":"10.1016/j.josat.2025.209768","DOIUrl":"10.1016/j.josat.2025.209768","url":null,"abstract":"<p><strong>Background: </strong>According to the Centers for Disease Control and Prevention (CDC), there was a 480 % increase in overdose deaths among all women from 1999 to 2021 (Jones et al., 2024). Women are uniquely impacted by substance use and overdose due to biological and cultural differences compared to men. CDC launched the Overdose Data to Action (OD2A) cooperative agreement in 2019 with the goal of helping to mitigate the opioid overdose crisis across the United States by supporting state and local health departments.</p><p><strong>Methods: </strong>This study focused on a review of programmatic data submitted by OD2A jurisdictions that detail their prevention activities to identify how jurisdictions implemented activities to address the unique needs of women. The team conducted systematic content analysis using multiple rounds of coding.</p><p><strong>Results: </strong>Most activities were tailored for pregnant women or women who had recently given birth and focused on expanding capacity to meet their needs. The most common activities were capacity-building activities to enhance efforts to address overdose needs for women (specifically pregnant women), resource development/sharing, and implementation/evaluation of best or promising practices for women.</p><p><strong>Conclusion: </strong>While it is important that activities tailored for pregnant women continue, our study showed a gap in activities tailored to other populations of women where the problem may be the greatest, such as women who are incarcerated, women who engage in sex work, and other female sub-populations. To address overdose rates in women, future efforts would benefit from continuing activities for pregnant women but also attempting to reach other at-risk female populations.</p>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":" ","pages":"209768"},"PeriodicalIF":1.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stigma and knowledge about medications for alcohol use disorder among treatment-seeking adults 寻求治疗的成年人对酒精使用障碍药物的耻辱感和知识。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-31 DOI: 10.1016/j.josat.2025.209831
Blake T. Hilton , Mia A. Haidamus , Victoria R. Votaw , Gerardo Gonzalez , Roger D. Weiss , Margaret L. Griffin , R. Kathryn McHugh

Introduction

Despite demonstrated effectiveness, medications for alcohol use disorder (MAUD) are underutilized. While studies have considered structural and provider-level barriers, little is known about patient-level factors associated with MAUD initiation. We aimed to examine stigma, knowledge, and beliefs about MAUD and their associations with intention to take them among a sample with severe AUD.

Methods

Adults receiving treatment for alcohol use disorder at an inpatient withdrawal management and treatment initiation program completed a cross-sectional survey (N = 171). MAUD knowledge (i.e., correctly identified medications for AUD), beliefs (i.e., perceived effectiveness), and stigma (i.e., internalized and perceived) in general and by medication type (i.e., naltrexone, acamprosate, and disulfiram) were assessed using a measure developed for this study.

Results

Knowledge about which medications are indicated for AUD was low, with the highest awareness for naltrexone (61 % of participants correctly identified this medication). Most (55 %) participants believed MAUD helps people recover, however approximately half were uncertain about the effectiveness of each specific medication type. Participants with greater MAUD knowledge and more positive beliefs about effectiveness reported greater intention to take MAUD (ps < 0.05). Stigma was low across all medications (mean scores <3 on a scale of 10), though a substantial portion of participants endorsed uncertainty about stigma.

Conclusions

Greater knowledge and positive beliefs about MAUD were significantly associated with intentions to pursue MAUD, yet many participants reported uncertainty in these domains. MAUD knowledge was low overall, as was stigma. Targeted efforts to enhance patient knowledge of MAUD could be a promising strategy for increasing medication uptake.
导论:尽管证明了药物治疗酒精使用障碍(MAUD)的有效性,但药物未得到充分利用。虽然研究考虑了结构性和提供者层面的障碍,但对与MAUD发生相关的患者层面因素知之甚少。我们的目的是研究耻辱感、知识和对MAUD的信念,以及它们与严重AUD样本的关联。方法:在住院戒断管理和治疗启动项目中接受酒精使用障碍治疗的成年人完成了一项横断面调查(N = 171)。使用为本研究开发的测量方法评估了AUD知识(即正确识别AUD药物),信念(即感知有效性)和耻辱感(即内化和感知),以及药物类型(即纳曲酮,阿坎普罗酸和双硫仑)。结果:对于哪些药物适用于AUD的知识很低,纳曲酮的认知度最高(61% %的参与者正确识别了这种药物)。大多数(55 %)参与者认为MAUD有助于人们康复,然而大约一半的人不确定每种特定药物类型的有效性。具有更多MAUD知识和更积极的有效性信念的参与者报告了更大的MAUD意图(ps 结论:关于MAUD的更多知识和积极信念与追求MAUD的意图显著相关,但许多参与者报告了这些领域的不确定性。总体而言,对疾病的了解程度很低,病耻感也很低。有针对性的努力,以提高患者的MAUD知识可能是一个有前途的策略,以增加药物摄取。
{"title":"Stigma and knowledge about medications for alcohol use disorder among treatment-seeking adults","authors":"Blake T. Hilton ,&nbsp;Mia A. Haidamus ,&nbsp;Victoria R. Votaw ,&nbsp;Gerardo Gonzalez ,&nbsp;Roger D. Weiss ,&nbsp;Margaret L. Griffin ,&nbsp;R. Kathryn McHugh","doi":"10.1016/j.josat.2025.209831","DOIUrl":"10.1016/j.josat.2025.209831","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite demonstrated effectiveness, medications for alcohol use disorder (MAUD) are underutilized. While studies have considered structural and provider-level barriers, little is known about patient-level factors associated with MAUD initiation. We aimed to examine stigma, knowledge, and beliefs about MAUD and their associations with intention to take them among a sample with severe AUD.</div></div><div><h3>Methods</h3><div>Adults receiving treatment for alcohol use disorder at an inpatient withdrawal management and treatment initiation program completed a cross-sectional survey (<em>N</em> = 171). MAUD knowledge (i.e., correctly identified medications for AUD), beliefs (i.e., perceived effectiveness), and stigma (i.e., internalized and perceived) in general and by medication type (i.e., naltrexone, acamprosate, and disulfiram) were assessed using a measure developed for this study.</div></div><div><h3>Results</h3><div>Knowledge about which medications are indicated for AUD was low, with the highest awareness for naltrexone (61 % of participants correctly identified this medication). Most (55 %) participants believed MAUD helps people recover, however approximately half were uncertain about the effectiveness of each specific medication type. Participants with greater MAUD knowledge and more positive beliefs about effectiveness reported greater intention to take MAUD (<em>p</em>s &lt; 0.05). Stigma was low across all medications (mean scores &lt;3 on a scale of 10), though a substantial portion of participants endorsed uncertainty about stigma.</div></div><div><h3>Conclusions</h3><div>Greater knowledge and positive beliefs about MAUD were significantly associated with intentions to pursue MAUD, yet many participants reported uncertainty in these domains. MAUD knowledge was low overall, as was stigma. Targeted efforts to enhance patient knowledge of MAUD could be a promising strategy for increasing medication uptake.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"180 ","pages":"Article 209831"},"PeriodicalIF":1.9,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145433000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local level of social inequity moderates implementation of evidence-based practices tailored to minoritized populations to reduce opioid overdose deaths 地方层面的社会不平等减缓了针对少数群体的循证做法的实施,以减少阿片类药物过量死亡。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-30 DOI: 10.1016/j.josat.2025.209828
Avik Chatterjee , Rachel P. Chase , Rouba A. Chahine , Jill Davis , Nishi Dsouza , Sylvia Ellison , Sarah M. Bagley , Tiarra Fisher , LaShawn Glasgow , Miriam T.H. Harris , Terry T.-K. Huang , JaNae Holloway , David W. Lounsbury , Emmanuel Oga , Kat Asman , Sara M. Roberts , Nasim Sabounchi , Hilary L. Surratt , Lisa M. Lines , Henry W. Stadler , Alissa Davis

Introduction

Evidence-based practices (EBPs) tailored to reduce opioid-related fatalities among minoritized populations may help reduce inequities, but research elucidating the relationship between local-level inequities in social determinants of health (SDH) and selection and implementation of tailored EBPs.

Methods

The HEALing Communities Study was a multisite, wait-listed, community-level cluster-randomized trial with the objective to reduce opioid overdose deaths. Community coalitions selected and partner organizations implemented EBP strategies to increase access to Overdose Education and Naloxone Distribution (OEND) and Medications for Opioid Use Disorder (MOUD). The research team utilized negative binomial and zero-inflated Poisson models to assess whether the relationship between (a) communities' need for tailored OEND and MOUD strategies, as indicated by opioid overdose death rates among minoritized groups; and (b) the selection, implementation, and reach of those strategies was moderated by local-level inequities in SDH, quantified by the Local Social Inequity in Drug Overdoses (LSI-DO) index. The analysis included data from 33 communities across four states.

Results

Eleven of 33 communities implemented tailored OEND and MOUD strategies. Adjusted analysis revealed that LSI-DO scores moderated the relationship between 2021 opioid overdose death rates among minoritized groups and the proportion of community-implemented tailored strategies (p = 0.015). The research team found no moderation for the number of strategies selected or number of individuals reached by EBPs.

Conclusion

Few communities selected EBPs tailored to minoritized populations. For those that did, higher local-level social inequity was associated with decreased implementation of tailored strategies. Continued research on how to address overdose inequities—and local-level social inequity—is vital. Findings highlight the need for policy approaches that pair overdose prevention strategies with investments to reduce local-level social inequities that impede equitable implementation.
引言:旨在减少少数群体中阿片类药物相关死亡的循证实践(ebp)可能有助于减少不公平现象,但研究阐明了健康社会决定因素(SDH)的地方不公平现象与定制ebp的选择和实施之间的关系。方法:康复社区研究是一项多地点、等待名单、社区水平的集群随机试验,目的是减少阿片类药物过量死亡。选定的社区联盟和伙伴组织实施了EBP战略,以增加获得过量教育和纳洛酮分发(OEND)以及阿片类药物使用障碍药物(mod)的机会。研究小组利用负二项和零膨胀泊松模型来评估(a)社区对量身定制的OEND和mod策略的需求之间的关系,如少数群体中阿片类药物过量死亡率所示;(b)这些策略的选择、实施和覆盖范围受到SDH的地方层面不平等的调节,SDH的地方层面不平等由药物过量的地方社会不平等(LSI-DO)指数量化。该分析包括来自四个州33个社区的数据。结果:33个社区中有11个实施了量身定制的OEND和mod策略。调整后的分析显示,LSI-DO评分调节了少数群体2021年阿片类药物过量死亡率与社区实施量身定制策略比例之间的关系(p = 0.015)。研究小组发现,ebp选择的策略数量或达到的个体数量没有调节。结论:很少有社区选择针对少数群体的EBPs。对于那些有这样做的国家来说,地方层面的社会不平等加剧与量身定制战略的实施减少有关。继续研究如何解决过量用药不公平问题——以及地方层面的社会不公平——至关重要。调查结果强调需要采取政策办法,将过量预防战略与投资结合起来,以减少妨碍公平实施的地方一级社会不公平现象。
{"title":"Local level of social inequity moderates implementation of evidence-based practices tailored to minoritized populations to reduce opioid overdose deaths","authors":"Avik Chatterjee ,&nbsp;Rachel P. Chase ,&nbsp;Rouba A. Chahine ,&nbsp;Jill Davis ,&nbsp;Nishi Dsouza ,&nbsp;Sylvia Ellison ,&nbsp;Sarah M. Bagley ,&nbsp;Tiarra Fisher ,&nbsp;LaShawn Glasgow ,&nbsp;Miriam T.H. Harris ,&nbsp;Terry T.-K. Huang ,&nbsp;JaNae Holloway ,&nbsp;David W. Lounsbury ,&nbsp;Emmanuel Oga ,&nbsp;Kat Asman ,&nbsp;Sara M. Roberts ,&nbsp;Nasim Sabounchi ,&nbsp;Hilary L. Surratt ,&nbsp;Lisa M. Lines ,&nbsp;Henry W. Stadler ,&nbsp;Alissa Davis","doi":"10.1016/j.josat.2025.209828","DOIUrl":"10.1016/j.josat.2025.209828","url":null,"abstract":"<div><h3>Introduction</h3><div>Evidence-based practices (EBPs) tailored to reduce opioid-related fatalities among minoritized populations may help reduce inequities, but research elucidating the relationship between local-level inequities in social determinants of health (SDH) and selection and implementation of tailored EBPs.</div></div><div><h3>Methods</h3><div>The HEALing Communities Study was a multisite, wait-listed, community-level cluster-randomized trial with the objective to reduce opioid overdose deaths. Community coalitions selected and partner organizations implemented EBP strategies to increase access to Overdose Education and Naloxone Distribution (OEND) and Medications for Opioid Use Disorder (MOUD). The research team utilized negative binomial and zero-inflated Poisson models to assess whether the relationship between (a) communities' need for tailored OEND and MOUD strategies, as indicated by opioid overdose death rates among minoritized groups; and (b) the selection, implementation, and reach of those strategies was moderated by local-level inequities in SDH, quantified by the Local Social Inequity in Drug Overdoses (LSI-DO) index. The analysis included data from 33 communities across four states.</div></div><div><h3>Results</h3><div>Eleven of 33 communities implemented tailored OEND and MOUD strategies. Adjusted analysis revealed that LSI-DO scores moderated the relationship between 2021 opioid overdose death rates among minoritized groups and the proportion of community-implemented tailored strategies (<em>p</em> = 0.015). The research team found no moderation for the number of strategies selected or number of individuals reached by EBPs.</div></div><div><h3>Conclusion</h3><div>Few communities selected EBPs tailored to minoritized populations. For those that did, higher local-level social inequity was associated with decreased implementation of tailored strategies. Continued research on how to address overdose inequities—and local-level social inequity—is vital. Findings highlight the need for policy approaches that pair overdose prevention strategies with investments to reduce local-level social inequities that impede equitable implementation.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"180 ","pages":"Article 209828"},"PeriodicalIF":1.9,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“If he did it, I can do it, too. I can change my life around”: The social model of recovery within the context of recovery homes accepting residents prescribed medications for opioid use disorder “如果他做到了,我也能做到。我可以改变我周围的生活”:康复之家接受居民处方阿片类药物使用障碍的社会康复模式。
IF 1.9 0 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-30 DOI: 10.1016/j.josat.2025.209830
Jodie M. Dewey , Kathryn R. Gallardo , Meenakshi S. Subbaraman , Amy A. Mericle

Introduction

This paper provides an in-depth examination of examines four recovery residences, that serve individuals prescribed medications for opioid use disorder (MOUD). The study has two primary aims: first, to deepen understanding of how recovery residences adopt and operationalize Social Model of Recovery principles; and second, to identify gaps in staff integration of residents receiving MOUD—gaps that may either support or undermine the integrity of the social model within these settings.

Methods

We conducted semi-structured interviews with 17 residents receiving MOUD living in four participating recovery homes. The interviews were conducted between August 2022 and January 2024 using a semi-structured interview guide designed to explore residents' experiences upon entering and living in the recovery home. Qualitative software was used to organize and qualitatively analyze transcripts through multiple rounds of coding. Themes were discussed across the research team and grouped across each of the various principles of the Social Model of Recovery.

Results

Residents reported feeling supported in safe, structured environments that promoted accountability and community, while staff with lived experience played a central role in fostering trust and modeling long-term recovery. Structured programming, peer coaching, and access to essential resources further reinforced recovery-supportive conditions. However, inconsistent staff attitudes toward MOUD revealed underlying stigma, which some residents found intrusive or isolating.

Conclusion

This study addresses key gaps in recovery science by offering qualitative insights into Level 3 recovery residences, emphasizing the perspectives of residents navigating staff relationships, organizational policies, and recovery programming. Despite increasing MOUD acceptance, recovery homes rarely address MOUD-related stigma formally, creating tension between medical and social models of recovery and contributing to judgment or marginalization of MOUD recipients. These findings highlight the urgent need for evidence-based MOUD integration strategies, staff education, and stigma reduction efforts to ensure that recovery homes fully support all residents' recovery pathways.
简介:本文提供了一个深入的检查检查四个康复住宅,服务于个人处方药物阿片类药物使用障碍(mod)。本研究有两个主要目的:一是加深对康复院如何采用和运作康复原则的社会模式的理解;第二,确定接受mod的居民在工作人员融入方面的差距——这些差距可能支持或破坏这些环境中社会模式的完整性。方法:我们对居住在四个参与康复之家的17名接受mod治疗的居民进行了半结构化访谈。访谈在2022年8月至2024年1月期间进行,采用半结构化访谈指南,旨在探索居民进入和居住在康复之家时的经历。通过多轮编码,使用定性软件对转录本进行组织和定性分析。整个研究团队讨论了主题,并根据社会康复模式的各个原则进行了分组。结果:居民报告在安全、结构化的环境中感受到支持,这种环境促进了问责制和社区,而有实际经验的工作人员在培养信任和塑造长期康复方面发挥了核心作用。有组织的规划、同伴指导以及获得必要资源的机会进一步加强了支持恢复的条件。然而,工作人员对mod的不一致态度揭示了潜在的耻辱感,一些居民认为这是一种侵扰或孤立。结论:本研究通过对三级康复住宅提供定性的见解,强调了居民在员工关系、组织政策和康复规划方面的视角,解决了康复科学的关键空白。尽管越来越多的人接受mod,但康复之家很少正式解决与mod相关的耻辱感,在康复的医疗模式和社会模式之间造成紧张关系,并导致对mod接受者的判断或边缘化。这些发现强调了迫切需要基于证据的mod整合战略,员工教育和减少耻辱感的努力,以确保康复之家充分支持所有居民的康复途径。
{"title":"“If he did it, I can do it, too. I can change my life around”: The social model of recovery within the context of recovery homes accepting residents prescribed medications for opioid use disorder","authors":"Jodie M. Dewey ,&nbsp;Kathryn R. Gallardo ,&nbsp;Meenakshi S. Subbaraman ,&nbsp;Amy A. Mericle","doi":"10.1016/j.josat.2025.209830","DOIUrl":"10.1016/j.josat.2025.209830","url":null,"abstract":"<div><h3>Introduction</h3><div>This paper provides an in-depth examination of examines four recovery residences, that serve individuals prescribed medications for opioid use disorder (MOUD). The study has two primary aims: first, to deepen understanding of how recovery residences adopt and operationalize Social Model of Recovery principles; and second, to identify gaps in staff integration of residents receiving MOUD—gaps that may either support or undermine the integrity of the social model within these settings.</div></div><div><h3>Methods</h3><div>We conducted semi-structured interviews with 17 residents receiving MOUD living in four participating recovery homes. The interviews were conducted between August 2022 and January 2024 using a semi-structured interview guide designed to explore residents' experiences upon entering and living in the recovery home. Qualitative software was used to organize and qualitatively analyze transcripts through multiple rounds of coding. Themes were discussed across the research team and grouped across each of the various principles of the Social Model of Recovery.</div></div><div><h3>Results</h3><div>Residents reported feeling supported in safe, structured environments that promoted accountability and community, while staff with lived experience played a central role in fostering trust and modeling long-term recovery. Structured programming, peer coaching, and access to essential resources further reinforced recovery-supportive conditions. However, inconsistent staff attitudes toward MOUD revealed underlying stigma, which some residents found intrusive or isolating.</div></div><div><h3>Conclusion</h3><div>This study addresses key gaps in recovery science by offering qualitative insights into Level 3 recovery residences, emphasizing the perspectives of residents navigating staff relationships, organizational policies, and recovery programming. Despite increasing MOUD acceptance, recovery homes rarely address MOUD-related stigma formally, creating tension between medical and social models of recovery and contributing to judgment or marginalization of MOUD recipients. These findings highlight the urgent need for evidence-based MOUD integration strategies, staff education, and stigma reduction efforts to ensure that recovery homes fully support all residents' recovery pathways.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"180 ","pages":"Article 209830"},"PeriodicalIF":1.9,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145427284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of substance use and addiction treatment
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1