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Misinformation and Overestimation of Computed Tomography Lung Cancer Screening Harms-Methodology Matters: A Joint Statement from The Society of Thoracic Surgeons, the American Society for Radiation Oncology, and the American College of Radiology. 计算机断层扫描肺癌筛查危害的错误信息和高估——方法问题:胸外科学会、美国放射肿瘤学学会和美国放射学会的联合声明。
Pub Date : 2025-12-29 DOI: 10.1016/j.jacr.2025.12.023
Haley I Tupper, Joseph B Shrager, Drew Moghanaki, Charles B Simone, Ella A Kazerooni, Eric M Hart, David T Cooke, Jeffrey B Velotta, Betty C Tong, Hari B Keshava, Cherie P Erkmen, Chi-Fu J Yang, Elliot L Servais
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引用次数: 0
Attrition in the Integrated Interventional Radiology Residency Program: 2017-2023. 综合介入放射住院医师计划的减员:2017 - 2023。
Pub Date : 2025-12-29 DOI: 10.1016/j.jacr.2025.12.025
Amina M Karage, Jeffrey Forris Beecham Chick, David S Shin, Mina S Makary, Jessica B Robbins, Eric J Monroe

Purpose: To evaluate attrition in integrated interventional radiology (IR) residency compared with the independent IR, diagnostic radiology (DR), integrated programs, and other residency programs.

Materials and methods: This study was conducted based on publicly available data published by the ACGME from 2017 to 2023. Residents were categorized as having transferred, withdrawn, dismissed, unsuccessfully completed, or deceased. Attrition was calculated by dividing the total number of departed residents by the total number of residents within a given specialty. Data for the IR residency was compared with other residency programs during the same period. Odds ratios (ORs) and P values were calculated using multivariate logistic regression and χ2 test. A P value < .05 was considered significant.

Results: Attrition for the integrated IR residency ranged from 2.3% to 5.1% during the 6-year period. Third-year IR (IR3) residents had the highest attrition at 6.70%. Attrition rates were significantly different between resident years, driven by a higher rate of attrition in resident year (RY)3 compared with RY1, RY2, and RY4. The odds of attrition in the independent IR and DR programs were, respectively, 77.6% and 52.9%, lower compared with the integrated IR program. The integrated IR residency attrition rates were comparable to general surgery (OR = 0.835; P = .178) and integrated thoracic surgery (OR = 0.751; P = .178) and higher than family medicine (OR = P < .001), neurological surgery (P < .001), integrated vascular surgery (P < .001), obstetrics and gynecology (P < .001), internal medicine (P < .001), orthopedic surgery (P < .001) and emergency medicine (P < .001) residency programs.

Conclusion: Findings from this study outline elevated attrition within the integrated IR programs. This study highlights a need for additional research to identify risk factors and potential interventions to improve medical student education, resident support and retention.

目的:评价综合介入放射学(IR)住院医师与独立介入放射学(IR)、诊断放射学(DR)、综合项目和其他住院医师项目的减员情况。材料和方法:本研究基于ACGME 2017年至2023年发布的公开数据进行。住院医师被分类为已转移、退出、解雇、未成功完成或死亡。流失率的计算方法是将离职的总人数除以某一专业的总人数。IR住院医师的数据与同期其他住院医师项目的数据进行了比较。采用多因素logistic回归和χ2检验计算优势比(ORs)和P值。A P值< 0.05被认为是显著的。结果:在6年期间,综合IR住院的损失率从2.3%到5.1%不等。第三年IR (IR3)居民的流失率最高,为6.70%。居住年限之间的流失率存在显著差异,其中居住年限(RY)3的流失率高于RY1、RY2和RY4。与综合IR计划相比,独立IR和DR计划的减员率分别为77.6%和52.9%。综合IR住院医师流失率与普通外科(OR = 0.835; P = 0.178)和综合胸外科(OR = 0.751; P = 0.178)相当,高于家庭医学(OR = P < 0.001)、神经外科(P < 0.001)、综合血管外科(P < 0.001)、妇产科(P < 0.001)、内科(P < 0.001)、骨科(P < 0.001)和急诊医学(P < 0.001)住院医师项目。结论:本研究的发现概述了综合IR计划中损耗的增加。本研究强调需要进一步的研究,以确定风险因素和潜在的干预措施,以改善医学生的教育,住院医生的支持和保留。
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引用次数: 0
US Radiology Imaging and Workforce Volumes 2017-2024: An Analysis of 46.4 Million Imaging Examinations From 167 Radiology Facilities. 2017年至2024年美国放射成像和劳动力数量:来自167个放射设施的4640万次成像检查的分析。
Pub Date : 2025-12-26 DOI: 10.1016/j.jacr.2025.12.026
Haniyeh Zamani, Tom Fruscello, Judy Burleson, Mythreyi Bhargavan-Chatfield, Matthew S Davenport

Purpose: To determine changes in site- and radiologist-specific imaging volumes before, during, and after the COVID-19 pandemic from a large, diverse sample of US radiology practices.

Methods: Imaging volumes (46.4 million examinations) for 1,571 unique radiologists and 167 United States radiology practices in 19 states (academic [n ≤ 5], community hospital [n = 71], multispecialty clinic [n ≤ 5], freestanding imaging center [n = 86], other [n ≤ 5]) participating in the ACR General Radiography Improvement Database (part of the National Radiology Data Registry, which is a CMS-approved Qualified Clinical Data Registry) from December 1, 2017, to February 29, 2024, were analyzed. These dates included baseline, pandemic, and postpandemic periods. Six modalities were analyzed: CT, mammography, MRI, x-ray, ultrasound, and PET-CT. National Provider Identifiers (NPIs) were used to track individual radiologists. Changes in workforce number (by NPI), workload (examinations per day), NPI attrition, and NPI turnover were calculated by quarter.

Results: Of 1,571 radiologists, 671 (43%) worked full time and read ≥100 examinations per quarter throughout the baseline period and final study quarter. Mean aggregate change in examinations read per day per radiologist from baseline to study end was modest (+0.6% [49.1 per day to 49.4 per day]). However, the top quartile radiologists (by examination volume) experienced meaningful increases in examinations per day (+30.6%; 73.9 examinations per day versus 56.6 examinations per day [baseline]) and clinical days worked per quarter (+19.7%; 46.2 days per quarter versus 38.6 days per quarter [baseline]). The number of working radiologists increased 23.6% (1,094 versus 885 [baseline]) with substantial turnover. Days worked per radiologist per quarter remained similar (37.2 days versus 39.1 days, -4.9%). Sharp examination declines during the COVID-19 pandemic were not associated with large reductions in the radiologist workforce.

Conclusion: Although the average radiologist read a similar number of examinations per day pre- versus postpandemic, the top quartile radiologists read 30.6% more examinations per day and work 19.7% more clinical shifts per quarter compared with the first quarter of 2018.

目的:从美国放射学实践的大量不同样本中确定2019冠状病毒病大流行之前、期间和之后部位和放射科医生特定成像体积的变化。方法:1571名独特放射科医生和19个州167名美国放射学实践的影像量(4640万次检查)(学术[n])结果:在1571名放射科医生中,671名(43%)是全职的,在基线期和最后研究季度阅读≥100次/季度。从基线到研究结束,每天检查次数/放射科医生的平均总变化不大(+0.6%[49.1次/天至49.4次/天])。然而,排名前四分之一的放射科医生(按检查量计算)的检查次数/天(+30.6%;73.9次检查/天对56.6次检查/天[基线])和临床工作天数/季度(+19.7%;46.2天/季度对38.6天/季度[基线])均有显著增加。放射科医生的工作人数增加了23.6%(1094人对885人[基线]),人员流动率很高。工作天数/放射科医生/季度保持相似(37.2天对39.1天,-4.9%)。在2019冠状病毒病大流行期间,检查人数急剧下降与放射科医生人数的大幅减少无关。结论:尽管平均放射科医生在大流行前后每天阅读的检查数量相似,但与2018年第一季度相比,排名前四分之一的放射科医生每天阅读的检查数量增加了30.6%,每季度的临床班次增加了19.7%。
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引用次数: 0
Factors Impacting the Performance of Deep Learning Detection of Pulmonary Emboli. 影响肺栓塞深度学习检测性能的因素。
Pub Date : 2025-12-26 DOI: 10.1016/j.jacr.2025.12.028
Vera Sorin, Panagiotis Korfiatis, Steve G Langer, Lewis D Hahn, Alex K Bratt, Cole J Cook, Joe D Sobek, Crystal L Butler, Christoph Wald, Bradley J Erickson, Jeremy D Collins

Objective: AI models are increasingly adopted in clinical practice, yet their generalizability outside controlled validation settings remains unclear. We aimed to evaluate the real-world performance of an FDA-cleared commercial pulmonary embolism (PE) detection model and identify technical, demographic, and clinical factors associated with performance variation, to inform postproduction monitoring and deployment strategies.

Methods: This retrospective study included 11,144 CT pulmonary angiography examinations performed in a single health system between April 2023 and June 2024, processed by a commercial PE detection model. Technical parameters (scanner manufacturer, slice thickness, dose index volume, contrast enhancement of pulmonary artery), demographic factors (age, gender, race, body mass index), and clinical comorbidities (heart failure, pulmonary hypertension, cancer) were extracted from DICOM headers and electronic health records. Univariate and multivariable logistic regression analyses identified factors associated with decreased performance.

Results: There were 1,193 of 11,144 (10.7%) PE-positive cases. The model had an overall 83.5% (95% confidence interval [CI] 81.3%-85.5%) sensitivity and positive predictive value was 90.5% (95% CI 88.7%-92.1%). Multivariable analysis showed significant associations between decreased sensitivity and scanner manufacturer (odds ratio [OR] 0.25, 95% CI 0.14-0.46 and OR 0.34, 95% CI 0.17-0.69, for different vendors versus reference, P < .003), increased slice thickness (OR 0.74, 95% CI 0.57-0.95 per 1-mm increase, P = .018), presence of imaging artifacts (OR 0.33, 95% CI 0.23-0.48, P < .001), heart failure (OR 0.58, 95% CI 0.38-0.88, P = .010), and pulmonary hypertension (OR 0.44, 95% CI 0.25-0.77, P = .004). Demographic factors including age, gender, race, and body mass index showed no significant associations with model performance.

Conclusion: AI performance in clinical practice varies significantly based on technical imaging parameters and patient comorbidities. Understanding these factors is essential for optimal product selection and for effective postdeployment monitoring, enabling investigation of model drift in evolving clinical settings. The findings highlight the need for local validation frameworks that account for institution-specific technical infrastructure and patient populations, to ensure safe AI deployment across diverse clinical environments.

目的:人工智能模型越来越多地应用于临床实践,但其在受控验证设置之外的泛化性尚不清楚。我们旨在评估fda批准的商业肺栓塞(PE)检测模型的实际性能,并确定与性能变化相关的技术、人口统计学和临床因素,为生产后监测和部署策略提供信息。方法:本回顾性研究纳入了2023年4月至2024年6月在单一卫生系统中进行的11,144次CT肺血管造影检查,并使用商用PE检测模型进行处理。从DICOM标头和电子健康记录中提取技术参数(扫描仪制造商、切片厚度、剂量指数体积、肺动脉造影剂增强)、人口统计学因素(年龄、性别、种族、BMI)和临床合并症(心力衰竭、肺动脉高压、癌症)。单变量和多变量逻辑回归分析确定了与性能下降相关的因素。结果:pe阳性1193 / 11144例(10.7%)。该模型总体敏感性为83.5%(95%置信区间[CI] 81.3% ~ 85.5%),阳性预测值(PPV)为90.5%(95%置信区间[CI] 88.7% ~ 92.1%)。多变量分析显示,不同厂商与参考厂商相比,敏感度降低与扫描仪制造商之间存在显著关联(比值比[OR] 0.25, 95%CI 0.14-0.46和0.34,95%CI 0.17-0.69)。结论:人工智能在临床实践中的表现因技术成像参数和患者合共病而有显著差异。了解这些因素对于优化产品选择和有效的部署后监测至关重要,从而能够在不断变化的临床环境中调查模型漂移。研究结果强调需要考虑到特定机构的技术基础设施和患者群体的本地验证框架,以确保在不同的临床环境中安全部署人工智能。
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引用次数: 0
Evaluating Generative Artificial Intelligence as an Educational Tool for Radiology Resident Report Drafting. 评估生成人工智能作为放射科住院医师报告起草的教育工具。
Pub Date : 2025-12-24 DOI: 10.1016/j.jacr.2025.12.024
Antonio Verdone, Aidan Cardall, Fardeen Siddiqui, Motaz Nashawaty, Danielle Rigau, Youngjoon Kwon, Mira Yousef, Shalin Patel, Alex Kieturakis, Eric Kim, Laura Heacock, Beatriu Reig, Yiqiu Shen

Objective: Radiology residents require timely, personalized feedback to develop accurate image analysis and reporting skills. Increasing clinical workload often limits attendings' ability to provide guidance. This study evaluates a HIPAA-compliant Generative Pretrained Transformer (GPT)-4o system that delivers automated feedback on breast imaging reports drafted by residents in real clinical settings.

Methods: We analyzed 5,000 resident-attending report pairs from routine practice at a multisite US health system. GPT-4o was prompted with clinical instructions to identify common errors and provide feedback. A reader study using 100 report pairs was conducted. Four attending radiologists and four residents independently reviewed each pair, determined whether predefined error types were present, and rated GPT-4o's feedback as helpful or not. Agreement between GPT and readers was assessed using percent match. Interreader reliability was measured with Krippendorff's α. Educational value was measured as the proportion of cases rated helpful.

Results: Three common error types were identified: (1) omission or addition of key findings, (2) incorrect use or omission of technical descriptors, and (3) final assessment inconsistent with findings. GPT-4o showed strong agreement with attending consensus: 90.5%, 78.3%, and 90.4% (Cohen's κ: 0.790, 0.550, and 0.615) across error types. Interreader reliability among all eight readers showed moderate to substantial variability (α = 0.767, 0.595, 0.567). When each reader was individually replaced with GPT-4o and interreader agreement among seven readers and GPT was recalculated, the effect was not statistically significant (Δ = -0.004 to 0.002, all P > .05). GPT's feedback was rated helpful in most cases: 89.8%, 83.0%, and 92.0%.

Discussion: ChatGPT-4o can reliably identify key educational errors. It may serve as a scalable tool to support radiology education.

目的:放射科住院医师需要及时、个性化的反馈,以培养准确的图像分析和报告技能。临床工作量的增加往往限制了主治医生提供指导的能力。本研究评估了一个符合hipaa标准的gpt - 40系统,该系统可以在真实临床环境中对住院医生起草的乳房成像报告提供自动反馈。方法:我们分析了5000对来自美国多地点卫生系统常规实践的住院医师-主治医师报告。临床指导提示gpt - 40识别常见错误并提供反馈。使用100对报告对进行了读者研究。四名主治放射科医生和四名住院医生独立审查了每一对,确定是否存在预定义的错误类型,并对gpt - 40的反馈是否有帮助进行了评分。GPT和读者之间的一致性使用匹配百分比进行评估。读者间信度用Krippendorff's alpha测量。教育价值以被评为有帮助的案例的比例来衡量。结果:确定了三种常见的错误类型:(1)遗漏或添加关键发现,(2)不正确使用或遗漏技术描述符,以及(3)最终评估与发现不一致。gpt - 40在错误类型上表现出与与会共识的强烈一致性:90.5%,78.3%和90.4% (Cohen’s κ: 0.790, 0.550和0.615)。8位读者的读者间信度呈现中等至显著差异(α = 0.767, 0.595, 0.567)。用GPT- 40单独替换每个阅读器,重新计算7个阅读器之间的一致性和GPT,效果无统计学意义(Δ = -0.004 ~ 0.002, p均为0.05)。在大多数情况下,GPT的反馈被评为有帮助:89.8%,83.0%和92.0%。讨论:chatgpt - 40可以可靠地识别关键的教育错误。它可以作为一个可扩展的工具来支持放射学教育。
{"title":"Evaluating Generative Artificial Intelligence as an Educational Tool for Radiology Resident Report Drafting.","authors":"Antonio Verdone, Aidan Cardall, Fardeen Siddiqui, Motaz Nashawaty, Danielle Rigau, Youngjoon Kwon, Mira Yousef, Shalin Patel, Alex Kieturakis, Eric Kim, Laura Heacock, Beatriu Reig, Yiqiu Shen","doi":"10.1016/j.jacr.2025.12.024","DOIUrl":"10.1016/j.jacr.2025.12.024","url":null,"abstract":"<p><strong>Objective: </strong>Radiology residents require timely, personalized feedback to develop accurate image analysis and reporting skills. Increasing clinical workload often limits attendings' ability to provide guidance. This study evaluates a HIPAA-compliant Generative Pretrained Transformer (GPT)-4o system that delivers automated feedback on breast imaging reports drafted by residents in real clinical settings.</p><p><strong>Methods: </strong>We analyzed 5,000 resident-attending report pairs from routine practice at a multisite US health system. GPT-4o was prompted with clinical instructions to identify common errors and provide feedback. A reader study using 100 report pairs was conducted. Four attending radiologists and four residents independently reviewed each pair, determined whether predefined error types were present, and rated GPT-4o's feedback as helpful or not. Agreement between GPT and readers was assessed using percent match. Interreader reliability was measured with Krippendorff's α. Educational value was measured as the proportion of cases rated helpful.</p><p><strong>Results: </strong>Three common error types were identified: (1) omission or addition of key findings, (2) incorrect use or omission of technical descriptors, and (3) final assessment inconsistent with findings. GPT-4o showed strong agreement with attending consensus: 90.5%, 78.3%, and 90.4% (Cohen's κ: 0.790, 0.550, and 0.615) across error types. Interreader reliability among all eight readers showed moderate to substantial variability (α = 0.767, 0.595, 0.567). When each reader was individually replaced with GPT-4o and interreader agreement among seven readers and GPT was recalculated, the effect was not statistically significant (Δ = -0.004 to 0.002, all P > .05). GPT's feedback was rated helpful in most cases: 89.8%, 83.0%, and 92.0%.</p><p><strong>Discussion: </strong>ChatGPT-4o can reliably identify key educational errors. It may serve as a scalable tool to support radiology education.</p>","PeriodicalId":73968,"journal":{"name":"Journal of the American College of Radiology : JACR","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12869900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Online Safety Screening on Outpatient MRI Workflow. 在线安全筛查对门诊MRI工作流程的影响。
Pub Date : 2025-12-17 DOI: 10.1016/j.jacr.2025.12.021
Sheena Y Chu, Elizabeth A Briel, Lu Mao, John W Garrett, Scott B Reeder, Ali Pirasteh
{"title":"Impact of Online Safety Screening on Outpatient MRI Workflow.","authors":"Sheena Y Chu, Elizabeth A Briel, Lu Mao, John W Garrett, Scott B Reeder, Ali Pirasteh","doi":"10.1016/j.jacr.2025.12.021","DOIUrl":"10.1016/j.jacr.2025.12.021","url":null,"abstract":"","PeriodicalId":73968,"journal":{"name":"Journal of the American College of Radiology : JACR","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The State of Artificial Intelligence 2025: Its Capabilities and Roles in Industry, Politics, and Radiology. 人工智能2025的状态:它在工业、政治和放射学中的能力和作用。
Pub Date : 2025-12-17 DOI: 10.1016/j.jacr.2025.12.019
Nathan Benaich, Elliot K Fishman, Linda C Chu, Steven P Rowe, Connor W Smith
{"title":"The State of Artificial Intelligence 2025: Its Capabilities and Roles in Industry, Politics, and Radiology.","authors":"Nathan Benaich, Elliot K Fishman, Linda C Chu, Steven P Rowe, Connor W Smith","doi":"10.1016/j.jacr.2025.12.019","DOIUrl":"10.1016/j.jacr.2025.12.019","url":null,"abstract":"","PeriodicalId":73968,"journal":{"name":"Journal of the American College of Radiology : JACR","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-Friendly Summary of the ACR Appropriateness Criteria®: Chronic Elbow Pain. 对患者友好的ACR适宜性标准总结:慢性肘部疼痛。
Pub Date : 2025-12-16 DOI: 10.1016/j.jacr.2025.12.017
Jonathan Burns, Shari T Jawetz
{"title":"Patient-Friendly Summary of the ACR Appropriateness Criteria®: Chronic Elbow Pain.","authors":"Jonathan Burns, Shari T Jawetz","doi":"10.1016/j.jacr.2025.12.017","DOIUrl":"10.1016/j.jacr.2025.12.017","url":null,"abstract":"","PeriodicalId":73968,"journal":{"name":"Journal of the American College of Radiology : JACR","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-Friendly Summary of the ACR Appropriateness Criteria®: Myelopathy. ACR适宜性标准的患者友好总结®:脊髓病。
Pub Date : 2025-12-16 DOI: 10.1016/j.jacr.2025.12.018
Maya Doyle, Vincent M Timpone
{"title":"Patient-Friendly Summary of the ACR Appropriateness Criteria®: Myelopathy.","authors":"Maya Doyle, Vincent M Timpone","doi":"10.1016/j.jacr.2025.12.018","DOIUrl":"10.1016/j.jacr.2025.12.018","url":null,"abstract":"","PeriodicalId":73968,"journal":{"name":"Journal of the American College of Radiology : JACR","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Venture Capital Investments in Radiology From 2000 to 2023. 放射学风险投资:2000-2023年的分析。
Pub Date : 2025-12-15 DOI: 10.1016/j.jacr.2025.12.016
Anirudh Bikmal, Ravi Dhawan, Alex B Boyle, Denys Shay

Objective: Venture capital (VC) is playing a growing role in driving innovation in health care. Although previous studies have examined VC trends in various medical fields, limited research has focused on investment patterns in radiology. This study aimed to assess VC investment trends in radiology-focused companies from 2000 to 2023 and to identify key areas of innovation.

Methods: A retrospective analysis of VC investments in radiology companies from 2000 to 2023 was conducted using the PitchBook database (PitchBook Data, Inc, Seattle, Washington). Companies were categorized into medical devices, health care services, artificial intelligence (AI) health care software, non-AI health care software, consumer goods, and biotechnology and drug discovery. Total capital investment, number of funded companies, clinical trials, and international patent filings were assessed. In addition, the associations of capital investment with patent and clinical trial activity, both used as proxies for innovation, were analyzed using Spearman's ρ.

Results: Between 2000 and 2023, 2,851 VC firms made 2,584 investments in 646 radiology companies, totaling $11.4 billion. Investment activity peaked in 2021 with $2.18 billion. The most funded categories were medical devices ($3.21 billion), AI health care software ($2.54 billion), and biotechnology ($2.08 billion). These companies were associated with a total of 267 clinical trials and 9,224 patents, with medical devices and AI health care software leading in innovation, accounting for 5,465 (59.2%) and 1,220 (13.2%) patents, respectively.

Conclusion: VC investment in radiology has grown considerably over the past two decades, particularly in health care software and medical devices. This trend underscores the increasing role of private capital in shaping innovation within radiology.

目的:风险投资(VC)在推动医疗保健创新方面发挥着越来越大的作用。虽然以前的研究考察了各种医学领域的风险投资趋势,但有限的研究集中在放射学的投资模式上。本研究旨在评估2000年至2023年以放射学为重点的公司的风险投资趋势,并确定关键的创新领域。方法:利用PitchBook数据库对2000 - 2023年放射学公司的VC投资情况进行回顾性分析。公司分为医疗设备、医疗保健服务、人工智能(AI)医疗保健软件、非人工智能医疗保健软件、消费品以及生物技术和药物发现。评估了总资本投资、资助公司数量、临床试验和国际专利申请量。此外,资本投资与专利和临床试验活动的关联,两者都被用作创新的代理,用斯皮尔曼ρ分析。结果:2000年至2023年间,2851家风险投资公司对646家放射学公司进行了2584笔投资,总计114亿美元。投资活动在2021年达到顶峰,达到21.8亿美元。投资最多的类别是医疗器械(32.1亿美元)、人工智能医疗保健软件(25.4亿美元)和生物技术(20.8亿美元)。这些公司共有267项临床试验和9224项专利,其中医疗器械和人工智能医疗保健软件的创新领先,分别占5465项(59.2%)和1220项(13.2%)专利。结论:在过去的二十年里,放射学领域的风险投资大幅增长,尤其是在医疗保健软件和医疗器械领域。这一趋势强调了私人资本在塑造放射学创新方面日益重要的作用。
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引用次数: 0
期刊
Journal of the American College of Radiology : JACR
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