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Developing a Research Center for Artificial Intelligence in Medicine 建立医学人工智能研究中心
Pub Date : 2024-12-01 DOI: 10.1016/j.mcpdig.2024.07.005
Curtis P. Langlotz MD, PhD , Johanna Kim MPH, MBA , Nigam Shah MBBS, PhD , Matthew P. Lungren MD, MPH , David B. Larson MD, MBA , Somalee Datta PhD , Fei Fei Li PhD , Ruth O’Hara PhD , Thomas J. Montine MD, PhD , Robert A. Harrington MD , Garry E. Gold MD, MS
Artificial intelligence (AI) and machine learning (ML) are driving innovation in biosciences and are already affecting key elements of medical scholarship and clinical care. Many schools of medicine are capitalizing on the promise of these new technologies by establishing academic units to catalyze and grow research and innovation in AI/ML. At Stanford University, we have developed a successful model for an AI/ML research center with support from academic leaders, clinical departments, extramural grants, and industry partners. The Center for Artificial Intelligence in Medicine and Imaging uses the following 4 key tactics to support AI/ML research: project-based learning opportunities that build interdisciplinary collaboration; internal grant programs that catalyze extramural funding; infrastructure that facilitates the rapid creation of large multimodal AI-ready clinical data sets; and educational and open data programs that engage the broader research community. The center is based on the premise that foundational and applied research are not in tension but instead are complementary. Solving important biomedical problems with AI/ML requires high-quality foundational team science that incorporates the knowledge and expertise of clinicians, clinician scientists, computer scientists, and data scientists. As AI/ML becomes an essential component of research and clinical care, multidisciplinary centers of excellence in AI/ML will become a key part of the scholarly portfolio of academic medical centers and will provide a foundation for the responsible, ethical, and fair implementation of AI/ML systems.
人工智能(AI)和机器学习(ML)正在推动生物科学的创新,并已经影响到医学奖学金和临床护理的关键要素。许多医学院正在利用这些新技术的前景,通过建立学术单位来促进和发展人工智能/机器学习的研究和创新。在斯坦福大学,我们在学术领袖、临床部门、校外资助和行业合作伙伴的支持下,为人工智能/机器学习研究中心开发了一个成功的模型。医学和成像中的人工智能中心使用以下4个关键策略来支持AI/ML研究:基于项目的学习机会,建立跨学科合作;促进校外资金的内部拨款计划;促进快速创建大型多模式人工智能临床数据集的基础设施;以及教育和开放数据项目,吸引更广泛的研究界参与。该中心的前提是基础研究和应用研究不是对立的,而是相辅相成的。用AI/ML解决重要的生物医学问题需要高质量的基础团队科学,结合临床医生、临床医生科学家、计算机科学家和数据科学家的知识和专业知识。随着人工智能/机器学习成为研究和临床护理的重要组成部分,人工智能/机器学习的多学科卓越中心将成为学术医疗中心学术组合的关键部分,并将为负责任、道德和公平地实施人工智能/机器学习系统提供基础。
{"title":"Developing a Research Center for Artificial Intelligence in Medicine","authors":"Curtis P. Langlotz MD, PhD ,&nbsp;Johanna Kim MPH, MBA ,&nbsp;Nigam Shah MBBS, PhD ,&nbsp;Matthew P. Lungren MD, MPH ,&nbsp;David B. Larson MD, MBA ,&nbsp;Somalee Datta PhD ,&nbsp;Fei Fei Li PhD ,&nbsp;Ruth O’Hara PhD ,&nbsp;Thomas J. Montine MD, PhD ,&nbsp;Robert A. Harrington MD ,&nbsp;Garry E. Gold MD, MS","doi":"10.1016/j.mcpdig.2024.07.005","DOIUrl":"10.1016/j.mcpdig.2024.07.005","url":null,"abstract":"<div><div>Artificial intelligence (AI) and machine learning (ML) are driving innovation in biosciences and are already affecting key elements of medical scholarship and clinical care. Many schools of medicine are capitalizing on the promise of these new technologies by establishing academic units to catalyze and grow research and innovation in AI/ML. At Stanford University, we have developed a successful model for an AI/ML research center with support from academic leaders, clinical departments, extramural grants, and industry partners. The Center for Artificial Intelligence in Medicine and Imaging uses the following 4 key tactics to support AI/ML research: project-based learning opportunities that build interdisciplinary collaboration; internal grant programs that catalyze extramural funding; infrastructure that facilitates the rapid creation of large multimodal AI-ready clinical data sets; and educational and open data programs that engage the broader research community. The center is based on the premise that foundational and applied research are not in tension but instead are complementary. Solving important biomedical problems with AI/ML requires high-quality foundational team science that incorporates the knowledge and expertise of clinicians, clinician scientists, computer scientists, and data scientists. As AI/ML becomes an essential component of research and clinical care, multidisciplinary centers of excellence in AI/ML will become a key part of the scholarly portfolio of academic medical centers and will provide a foundation for the responsible, ethical, and fair implementation of AI/ML systems.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"2 4","pages":"Pages 677-686"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142744031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Health Interventions Supporting Recovery for Intensive Care Patients and Their Family Members: A Scoping Review
Pub Date : 2024-11-30 DOI: 10.1016/j.mcpdig.2024.11.006
Elke Berger MSc , Carola Schol MSc , Sabrina Meertens-Gunput PhD , Dorien Kiers MD, PhD , Diederik Gommers MD, PhD , Louise Rose PhD , Margo van Mol PhD
Digital innovation in interventions to promote recovery for intensive care unit (ICU) patients and their family members holds promise for enhancing accessibility and improving physical, psychological, and cognitive outcomes. This scoping review provides a comprehensive overview of digital health interventions designed to support the recovery of ICU patients and their family members described in peer-reviewed publications. We searched 6 databases (inception to September 2023); 2 reviewers independently screened citations against predefined eligibility criteria and extracted data. We screened 3485 records and identified 18 original studies and 8 study protocols with a range of study designs published between 2016 and 2023. Most (n=15) completed studies recruited patients only. Digital interventions were delivered through applications, virtual reality, videoconferencing, and smartwatches. In the completed studies, outcomes are described as feasibility, intervention efficacy, or both. Digital interventions supplemented with professional support and personalized feedback were more feasible than self-directed interventions. Further research is essential to ascertain the efficacy and cost-effectiveness of digital interventions in improving outcomes for ICU survivors and their family members.
{"title":"Digital Health Interventions Supporting Recovery for Intensive Care Patients and Their Family Members: A Scoping Review","authors":"Elke Berger MSc ,&nbsp;Carola Schol MSc ,&nbsp;Sabrina Meertens-Gunput PhD ,&nbsp;Dorien Kiers MD, PhD ,&nbsp;Diederik Gommers MD, PhD ,&nbsp;Louise Rose PhD ,&nbsp;Margo van Mol PhD","doi":"10.1016/j.mcpdig.2024.11.006","DOIUrl":"10.1016/j.mcpdig.2024.11.006","url":null,"abstract":"<div><div>Digital innovation in interventions to promote recovery for intensive care unit (ICU) patients and their family members holds promise for enhancing accessibility and improving physical, psychological, and cognitive outcomes. This scoping review provides a comprehensive overview of digital health interventions designed to support the recovery of ICU patients and their family members described in peer-reviewed publications. We searched 6 databases (inception to September 2023); 2 reviewers independently screened citations against predefined eligibility criteria and extracted data. We screened 3485 records and identified 18 original studies and 8 study protocols with a range of study designs published between 2016 and 2023. Most (n=15) completed studies recruited patients only. Digital interventions were delivered through applications, virtual reality, videoconferencing, and smartwatches. In the completed studies, outcomes are described as feasibility, intervention efficacy, or both. Digital interventions supplemented with professional support and personalized feedback were more feasible than self-directed interventions. Further research is essential to ascertain the efficacy and cost-effectiveness of digital interventions in improving outcomes for ICU survivors and their family members.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 1","pages":"Article 100185"},"PeriodicalIF":0.0,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fine-Tuning Large Language Models for Specialized Use Cases
Pub Date : 2024-11-29 DOI: 10.1016/j.mcpdig.2024.11.005
D.M. Anisuzzaman PhD, Jeffrey G. Malins PhD, Paul A. Friedman MD, Zachi I. Attia PhD
Large language models (LLMs) are a type of artificial intelligence, which operate by predicting and assembling sequences of words that are statistically likely to follow from a given text input. With this basic ability, LLMs are able to answer complex questions and follow extremely complex instructions. Products created using LLMs such as ChatGPT by OpenAI and Claude by Anthropic have created a huge amount of traction and user engagements and revolutionized the way we interact with technology, bringing a new dimension to human-computer interaction. Fine-tuning is a process in which a pretrained model, such as an LLM, is further trained on a custom data set to adapt it for specialized tasks or domains. In this review, we outline some of the major methodologic approaches and techniques that can be used to fine-tune LLMs for specialized use cases and enumerate the general steps required for carrying out LLM fine-tuning. We then illustrate a few of these methodologic approaches by describing several specific use cases of fine-tuning LLMs across medical subspecialties. Finally, we close with a consideration of some of the benefits and limitations associated with fine-tuning LLMs for specialized use cases, with an emphasis on specific concerns in the field of medicine.
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引用次数: 0
Development of a Human Factors–Based Guideline to Support the Design, Evaluation, and Continuous Improvement of Clinical Decision Support
Pub Date : 2024-11-27 DOI: 10.1016/j.mcpdig.2024.11.003
Selvana Awad BPharm, MHSM , Thomas Loveday MPsych, PhD , Richard Lau BPsychSc , Melissa T. Baysari BPsych, PhD

Objective

To develop a vendor-agnostic, human factors (HF)-based guideline to guide the design, evaluation, and continuous improvement of clinical decision support (CDS).

Participants and Methods

The study used a 2-phased iterative approach between June 2022 and June 2024. Phase 1 involved a search for relevant industry standards and literature and consultation with multidisciplinary subject matter experts. Phase 2 involved a workshop with 30 health care and academic stakeholders to evaluate face validity and perceived usefulness of the initial section of the guideline. Participants were asked if the guideline met their expectations, to report on usefulness and ease of use and to suggest areas for improvement.

Results

Phase 1 resulted in a compilation of accessible, best practice, and context-appropriate HF guidance for CDS design and optimization. The guideline supports users in determining whether use of CDS is appropriate, and if yes, CDS options and design guidance. During phase 2, the guideline addressed 15 of participants’ 19 expectations for a CDS guideline. Participants said the guideline was helpful, comprehensive, easy to use, and provided step-by-step guidance, boundaries, and transparency around CDS decisions. Participants recommended strengthening guidance around the need to understand system capabilities and the technical burden or complexity of CDS, and further guidance on how to approach CDS optimization using the guideline.

Conclusion

The 2-phased iterative development and feedback process resulted in the development of an HF-informed guideline to provide consolidated, accessible, and current best practice guidance on the appropriateness of CDS and CDS options, as well as designing, evaluating, and continuously improving CDS. Future work will evaluate the impact and implementation of the guideline in real-world settings.
{"title":"Development of a Human Factors–Based Guideline to Support the Design, Evaluation, and Continuous Improvement of Clinical Decision Support","authors":"Selvana Awad BPharm, MHSM ,&nbsp;Thomas Loveday MPsych, PhD ,&nbsp;Richard Lau BPsychSc ,&nbsp;Melissa T. Baysari BPsych, PhD","doi":"10.1016/j.mcpdig.2024.11.003","DOIUrl":"10.1016/j.mcpdig.2024.11.003","url":null,"abstract":"<div><h3>Objective</h3><div>To develop a vendor-agnostic, human factors (HF)-based guideline to guide the design, evaluation, and continuous improvement of clinical decision support (CDS).</div></div><div><h3>Participants and Methods</h3><div>The study used a 2-phased iterative approach between June 2022 and June 2024. Phase 1 involved a search for relevant industry standards and literature and consultation with multidisciplinary subject matter experts. Phase 2 involved a workshop with 30 health care and academic stakeholders to evaluate face validity and perceived usefulness of the initial section of the guideline. Participants were asked if the guideline met their expectations, to report on usefulness and ease of use and to suggest areas for improvement.</div></div><div><h3>Results</h3><div>Phase 1 resulted in a compilation of accessible, best practice, and context-appropriate HF guidance for CDS design and optimization. The guideline supports users in determining whether use of CDS is appropriate, and if yes, CDS options and design guidance. During phase 2, the guideline addressed 15 of participants’ 19 expectations for a CDS guideline. Participants said the guideline was helpful, comprehensive, easy to use, and provided step-by-step guidance, boundaries, and transparency around CDS decisions. Participants recommended strengthening guidance around the need to understand system capabilities and the technical burden or complexity of CDS, and further guidance on how to approach CDS optimization using the guideline.</div></div><div><h3>Conclusion</h3><div>The 2-phased iterative development and feedback process resulted in the development of an HF-informed guideline to provide consolidated, accessible, and current best practice guidance on the appropriateness of CDS and CDS options, as well as designing, evaluating, and continuously improving CDS. Future work will evaluate the impact and implementation of the guideline in real-world settings.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 1","pages":"Article 100182"},"PeriodicalIF":0.0,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pub Date : 2024-11-27 DOI: 10.1016/j.mcpdig.2024.11.007
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引用次数: 0
Gait Speed and Task Specificity in Predicting Lower-Limb Kinematics: A Deep Learning Approach Using Inertial Sensors
Pub Date : 2024-11-27 DOI: 10.1016/j.mcpdig.2024.11.004
Vaibhav R. Shah MSc , Philippe C. Dixon PhD

Objective

To develop a deep learning framework to predict lower-limb joint kinematics from inertial measurement unit (IMU) data across multiple gait tasks (walking, jogging, and running) and evaluate the impact of dynamic time warping (DTW) on reducing prediction errors.

Patients and Methods

Data were collected from 18 participants fitted with IMUs and an optical motion capture system between May 25, 2023, and May 30, 2023. A long short-term memory autoencoder supervised regression model was developed. The model consisted of multiple long short-term memory and convolution layers. Acceleration and gyroscope data from the IMUs in 3 axes and their magnitude for the proximal and distal sensors of each joint (hip, knee, and ankle) were inputs to the model. Optical motion capture kinematics were considered ground truth and used as an output to train the prediction model.

Results

The deep learning models achieved a root-mean-square error of less than 6° for hip, knee, and ankle joint sagittal plane angles, with the ankle showing the lowest error (5.1°). Task-specific models reported enhanced performance during certain gait phases, such as knee flexion during running. The application of DTW significantly reduced root-mean-square error across all tasks by at least 3° to 4°. External validation of independent data confirmed the model’s generalizability.

Conclusion

Our findings underscore the potential of IMU-based deep learning models for joint kinematic predictions, offering a practical solution for remote and continuous biomechanical assessments in health care and sports science.
{"title":"Gait Speed and Task Specificity in Predicting Lower-Limb Kinematics: A Deep Learning Approach Using Inertial Sensors","authors":"Vaibhav R. Shah MSc ,&nbsp;Philippe C. Dixon PhD","doi":"10.1016/j.mcpdig.2024.11.004","DOIUrl":"10.1016/j.mcpdig.2024.11.004","url":null,"abstract":"<div><h3>Objective</h3><div>To develop a deep learning framework to predict lower-limb joint kinematics from inertial measurement unit (IMU) data across multiple gait tasks (walking, jogging, and running) and evaluate the impact of dynamic time warping (DTW) on reducing prediction errors.</div></div><div><h3>Patients and Methods</h3><div>Data were collected from 18 participants fitted with IMUs and an optical motion capture system between May 25, 2023, and May 30, 2023. A long short-term memory autoencoder supervised regression model was developed. The model consisted of multiple long short-term memory and convolution layers. Acceleration and gyroscope data from the IMUs in 3 axes and their magnitude for the proximal and distal sensors of each joint (hip, knee, and ankle) were inputs to the model. Optical motion capture kinematics were considered ground truth and used as an output to train the prediction model.</div></div><div><h3>Results</h3><div>The deep learning models achieved a root-mean-square error of less than 6° for hip, knee, and ankle joint sagittal plane angles, with the ankle showing the lowest error (5.1°). Task-specific models reported enhanced performance during certain gait phases, such as knee flexion during running. The application of DTW significantly reduced root-mean-square error across all tasks by at least 3° to 4°. External validation of independent data confirmed the model’s generalizability.</div></div><div><h3>Conclusion</h3><div>Our findings underscore the potential of IMU-based deep learning models for joint kinematic predictions, offering a practical solution for remote and continuous biomechanical assessments in health care and sports science.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 1","pages":"Article 100183"},"PeriodicalIF":0.0,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effectiveness of Telehealth Intervention on Chronic Kidney Disease Management in Adults: A Systematic Review
Pub Date : 2024-11-16 DOI: 10.1016/j.mcpdig.2024.11.002
Tess Ellis MS, RD, Anna J. Kwon MS, Mee Young Hong PhD

Objective

To evaluate the effectiveness of telehealth programs on dietary habits, quality of life, renal function, and blood pressure in adults with chronic kidney disease (CKD).

Patients and Methods

A systematic literature review was completed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Using PubMed/Medline, Scopus, Embase, and ScienceDirect databases, articles published between 2012 and 2024 were selected using the following keywords: telehealth, eHealth, mHealth, telemedicine, telenutrition, and chronic kidney disease.

Results

A total of 13 studies—10 randomized controlled trials and 3 single-arm trials—were chosen for this review. In these trials, telehealth interventions were administered using mobile applications, phone calls, web-based communications, text messaging, wearable devices, or a combination of these tools to provide treatment for adults with CKD. Interdisciplinary collaboration between a dietitian and other health care team members was shown to improve renal function and dietary habits when providing telehealth interventions via mobile applications, phone calls, and text messaging. Web-based telehealth delivery that involves diverse health care personnel has been shown to improve the quality of life in adult patients with CKD.

Conclusion

Receiving treatment using telehealth communication methods may be a beneficial option for adult patients with CKD by enhancing accessibility, promoting multidisciplinary collaboration, and effectively managing blood pressure and dietary habits, leading to improved quality of life for patients. Future research administering homogeneous and rigorously controlled experimental methods with larger and more diverse populations, as well as longer study durations, is necessary to further elucidate the effectiveness of CKD treatment delivery via telehealth for adult patients.
{"title":"The Effectiveness of Telehealth Intervention on Chronic Kidney Disease Management in Adults: A Systematic Review","authors":"Tess Ellis MS, RD,&nbsp;Anna J. Kwon MS,&nbsp;Mee Young Hong PhD","doi":"10.1016/j.mcpdig.2024.11.002","DOIUrl":"10.1016/j.mcpdig.2024.11.002","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the effectiveness of telehealth programs on dietary habits, quality of life, renal function, and blood pressure in adults with chronic kidney disease (CKD).</div></div><div><h3>Patients and Methods</h3><div>A systematic literature review was completed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Using PubMed/Medline, Scopus, Embase, and ScienceDirect databases, articles published between 2012 and 2024 were selected using the following keywords: <em>telehealth</em>, <em>eHealth</em>, <em>mHealth</em>, <em>telemedicine</em>, <em>telenutrition</em>, and <em>chronic kidney disease</em>.</div></div><div><h3>Results</h3><div>A total of 13 studies—10 randomized controlled trials and 3 single-arm trials—were chosen for this review. In these trials, telehealth interventions were administered using mobile applications, phone calls, web-based communications, text messaging, wearable devices, or a combination of these tools to provide treatment for adults with CKD. Interdisciplinary collaboration between a dietitian and other health care team members was shown to improve renal function and dietary habits when providing telehealth interventions via mobile applications, phone calls, and text messaging. Web-based telehealth delivery that involves diverse health care personnel has been shown to improve the quality of life in adult patients with CKD.</div></div><div><h3>Conclusion</h3><div>Receiving treatment using telehealth communication methods may be a beneficial option for adult patients with CKD by enhancing accessibility, promoting multidisciplinary collaboration, and effectively managing blood pressure and dietary habits, leading to improved quality of life for patients. Future research administering homogeneous and rigorously controlled experimental methods with larger and more diverse populations, as well as longer study durations, is necessary to further elucidate the effectiveness of CKD treatment delivery via telehealth for adult patients.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 1","pages":"Article 100181"},"PeriodicalIF":0.0,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Medicine Tools and the Work of Being a Patient: A Qualitative Investigation of Digital Treatment Burden in Patients With Diabetes
Pub Date : 2024-11-16 DOI: 10.1016/j.mcpdig.2024.11.001
Misk A. Al Zahidy MS , Sue Simha BS , Megan Branda MS , Mariana Borras-Osorio MD , Maeva Haemmerle , Viet-Thi Tran MD, PhD , Jennifer L. Ridgeway PhD , Victor M. Montori MD

Objective

To understand the contribution of digital medicine tools (eg, continuous glucose monitoring systems, scheduling, and messaging applications) to treatment burden in patients with diabetes.

Patients and Methods

Between October and November 2023, we invited patients with type 1 or type 2 diabetes to participate in semistructured interviews. The interviewees completed the Treatment Burden Questionnaire as they reflected on how digital medicine tools affect their daily routines. A published taxonomy of treatment burden guided the qualitative content analysis of interview transcripts.

Results

In total, 20 patients agreed to participate and completed interviews (aged 21-77 years, 55% female, 60% living with type 2 diabetes). We found 5 categories of tasks related to the use of digital medicine tools that patients had to complete (eg, calibrating continuous glucose monitors), 3 factors that made these tasks burdensome (eg, cost of device replacements), and 2 categories of consequences of burdensome tasks on patient wellbeing (eg, fatigue from device alarms).

Conclusion

Patients identified how digital medicine tools contribute to their treatment burden. The resulting digital burden taxonomy can be used to inform the design, implementation, and prescription of digital medicine tools including support for patients as they normalize them in their lives.
{"title":"Digital Medicine Tools and the Work of Being a Patient: A Qualitative Investigation of Digital Treatment Burden in Patients With Diabetes","authors":"Misk A. Al Zahidy MS ,&nbsp;Sue Simha BS ,&nbsp;Megan Branda MS ,&nbsp;Mariana Borras-Osorio MD ,&nbsp;Maeva Haemmerle ,&nbsp;Viet-Thi Tran MD, PhD ,&nbsp;Jennifer L. Ridgeway PhD ,&nbsp;Victor M. Montori MD","doi":"10.1016/j.mcpdig.2024.11.001","DOIUrl":"10.1016/j.mcpdig.2024.11.001","url":null,"abstract":"<div><h3>Objective</h3><div>To understand the contribution of digital medicine tools (eg, continuous glucose monitoring systems, scheduling, and messaging applications) to treatment burden in patients with diabetes.</div></div><div><h3>Patients and Methods</h3><div>Between October and November 2023, we invited patients with type 1 or type 2 diabetes to participate in semistructured interviews. The interviewees completed the Treatment Burden Questionnaire as they reflected on how digital medicine tools affect their daily routines. A published taxonomy of treatment burden guided the qualitative content analysis of interview transcripts.</div></div><div><h3>Results</h3><div>In total, 20 patients agreed to participate and completed interviews (aged 21-77 years, 55% female, 60% living with type 2 diabetes). We found 5 categories of tasks related to the use of digital medicine tools that patients had to complete (eg, calibrating continuous glucose monitors), 3 factors that made these tasks burdensome (eg, cost of device replacements), and 2 categories of consequences of burdensome tasks on patient wellbeing (eg, fatigue from device alarms).</div></div><div><h3>Conclusion</h3><div>Patients identified how digital medicine tools contribute to their treatment burden. The resulting digital burden taxonomy can be used to inform the design, implementation, and prescription of digital medicine tools including support for patients as they normalize them in their lives.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 1","pages":"Article 100180"},"PeriodicalIF":0.0,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategic Considerations for Selecting Artificial Intelligence Solutions for Institutional Integration: A Single-Center Experience 为机构整合选择人工智能解决方案的战略考虑因素:单个中心的经验
Pub Date : 2024-11-05 DOI: 10.1016/j.mcpdig.2024.10.004
Janice L. Pascoe BRMP , Luqing Lu MS , Matthew M. Moore MFA , Daniel J. Blezek PhD , Annie E. Ovalle BS , Jane A. Linderbaum APRN, CNP , Matthew R. Callstrom MD, PhD , Eric E. Williamson MD
Artificial intelligence (AI) promises to revolutionize health care. Early identification of disease, appropriate test selection, and automation of repetitive tasks are expected to optimize cost-effective care delivery. However, pragmatic selection and integration of AI algorithms to enable this transformation remain challenging. Health care leaders must navigate complex decisions regarding AI deployment, considering factors such as cost of implementation, benefits to patients and providers, and institutional readiness for adoption. A successful strategy needs to align AI adoption with institutional priorities, select appropriate algorithms to be purchased or internally developed, and ensure adequate support and infrastructure. Further, successful deployment requires algorithm validation and workflow integration to ensure efficacy and usability. User-centric design principles and usability testing are critical for AI adoption, ensuring seamless integration into clinical workflows. Once deployed, continuous improvement processes and ongoing algorithm support ensure continuous benefits to the clinical practice. Vigilant planning and execution are necessary to navigate the complexities of AI implementation in the health care environment. By applying the framework outlined in this article, institutions can navigate the ever-evolving and complex environment of AI in health care to maximize the benefits of these innovative technologies.
人工智能(AI)有望彻底改变医疗保健。疾病的早期识别、适当的测试选择以及重复性任务的自动化有望优化具有成本效益的医疗服务。然而,如何务实地选择和整合人工智能算法以实现这一变革仍然充满挑战。医疗保健领导者必须在人工智能部署方面做出复杂的决策,考虑实施成本、对患者和医疗服务提供者的益处以及机构对采用人工智能的准备程度等因素。成功的战略需要将人工智能的采用与机构的优先事项相结合,选择合适的算法进行购买或内部开发,并确保有足够的支持和基础设施。此外,成功的部署需要算法验证和工作流程整合,以确保有效性和可用性。以用户为中心的设计原则和可用性测试对采用人工智能至关重要,可确保无缝集成到临床工作流程中。一旦部署,持续改进流程和不断的算法支持可确保临床实践持续获益。要在复杂的医疗环境中实施人工智能,就必须进行严密的规划和执行。通过应用本文概述的框架,医疗机构可以驾驭人工智能在医疗保健领域不断发展的复杂环境,最大限度地发挥这些创新技术的优势。
{"title":"Strategic Considerations for Selecting Artificial Intelligence Solutions for Institutional Integration: A Single-Center Experience","authors":"Janice L. Pascoe BRMP ,&nbsp;Luqing Lu MS ,&nbsp;Matthew M. Moore MFA ,&nbsp;Daniel J. Blezek PhD ,&nbsp;Annie E. Ovalle BS ,&nbsp;Jane A. Linderbaum APRN, CNP ,&nbsp;Matthew R. Callstrom MD, PhD ,&nbsp;Eric E. Williamson MD","doi":"10.1016/j.mcpdig.2024.10.004","DOIUrl":"10.1016/j.mcpdig.2024.10.004","url":null,"abstract":"<div><div>Artificial intelligence (AI) promises to revolutionize health care. Early identification of disease, appropriate test selection, and automation of repetitive tasks are expected to optimize cost-effective care delivery. However, pragmatic selection and integration of AI algorithms to enable this transformation remain challenging. Health care leaders must navigate complex decisions regarding AI deployment, considering factors such as cost of implementation, benefits to patients and providers, and institutional readiness for adoption. A successful strategy needs to align AI adoption with institutional priorities, select appropriate algorithms to be purchased or internally developed, and ensure adequate support and infrastructure. Further, successful deployment requires algorithm validation and workflow integration to ensure efficacy and usability. User-centric design principles and usability testing are critical for AI adoption, ensuring seamless integration into clinical workflows. Once deployed, continuous improvement processes and ongoing algorithm support ensure continuous benefits to the clinical practice. Vigilant planning and execution are necessary to navigate the complexities of AI implementation in the health care environment. By applying the framework outlined in this article, institutions can navigate the ever-evolving and complex environment of AI in health care to maximize the benefits of these innovative technologies.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"2 4","pages":"Pages 665-676"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviewers for Mayo Clinic Proceedings: Digital Health (2024) 梅奥诊所论文集》审稿人:数字健康(2024)
Pub Date : 2024-10-31 DOI: 10.1016/j.mcpdig.2024.10.005
{"title":"Reviewers for Mayo Clinic Proceedings: Digital Health (2024)","authors":"","doi":"10.1016/j.mcpdig.2024.10.005","DOIUrl":"10.1016/j.mcpdig.2024.10.005","url":null,"abstract":"","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"2 4","pages":"Pages 645-646"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Mayo Clinic Proceedings. Digital health
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