J. Fatima, V. Shukla, Z. Siddiqi, Mohammad Shamsi, Saboor Mateen, Aaliya Jabbar, Zeenat Usmani
{"title":"Cardiovascular risk markers (computed tomography‑coronary artery calcium and carotid intima‑media thickness) in patients with rheumatoid arthritis and controls","authors":"J. Fatima, V. Shukla, Z. Siddiqi, Mohammad Shamsi, Saboor Mateen, Aaliya Jabbar, Zeenat Usmani","doi":"10.3892/mi.2024.176","DOIUrl":"https://doi.org/10.3892/mi.2024.176","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Vilar, Eduardo Serrano, Philip Brabyn, M. Diez, Alberto Gutierrez
{"title":"Multiple giant cutaneous metastasis and ileal intussusception from an unknown melanoma: A case report","authors":"Alberto Vilar, Eduardo Serrano, Philip Brabyn, M. Diez, Alberto Gutierrez","doi":"10.3892/mi.2024.175","DOIUrl":"https://doi.org/10.3892/mi.2024.175","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"87 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141657786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michail Athanasopoulos, Georgios Nomikos, Pinelopi Samara, S. Mastronikolis, Christos Tsilivigkos, Nicholas Mastronikolis
{"title":"Non‑Hodgkin's lymphomas of the lacrimal sac: Current insights and future directions (Review)","authors":"Michail Athanasopoulos, Georgios Nomikos, Pinelopi Samara, S. Mastronikolis, Christos Tsilivigkos, Nicholas Mastronikolis","doi":"10.3892/mi.2024.167","DOIUrl":"https://doi.org/10.3892/mi.2024.167","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":" 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141366084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arya Harikrishna, Stefanos Chatzidakis, Angela Ishak, Konstantinos Faropoulos, George Fotakopoulos, V. Georgakopoulou, P. Sklapani, N. Trakas, Andreas Yiallouris, Christina Iosif, Aris Agouridis, George Hadjigeorgiou
{"title":"Awake craniotomy in patients with arteriovenous malformation: A systematic review and meta‑analysis","authors":"Arya Harikrishna, Stefanos Chatzidakis, Angela Ishak, Konstantinos Faropoulos, George Fotakopoulos, V. Georgakopoulou, P. Sklapani, N. Trakas, Andreas Yiallouris, Christina Iosif, Aris Agouridis, George Hadjigeorgiou","doi":"10.3892/mi.2024.166","DOIUrl":"https://doi.org/10.3892/mi.2024.166","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"105 s411","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141376935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
George Fotakopoulos, Ioannis Siasios, C. Gatos, V. Georgakopoulou, N. Trakas, P. Sklapani, K. Fountas
{"title":"Acute intracranial hemorrhage during the installation of the LICOX microdialysis system: A case report","authors":"George Fotakopoulos, Ioannis Siasios, C. Gatos, V. Georgakopoulou, N. Trakas, P. Sklapani, K. Fountas","doi":"10.3892/mi.2024.163","DOIUrl":"https://doi.org/10.3892/mi.2024.163","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"48 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140965723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Obeidat, Ali Obeidat, Abedallah Obeidat, Mohamed Ismail
. Doxorubicin (DOX), a cornerstone of cancer chemotherapy, is marred by its dose‑dependent cardiotoxicity, leading to cardiomyopathy and heart failure. The epidemi‑ ology of DOX‑related cardiotoxicity highlights its cumulative, progressive nature, with a significant impact on the health of patients. The pathophysiological mechanisms involve mitochondrial dysfunction, oxidative stress and disrupted calcium homeostasis in cardiomyocytes. Despite the search for effective cardioprotective strategies, current treatments offer limited efficacy. Visnagin emerges as a potential solution, known for its vasodilatory and anti‑inflammatory properties, and recent studies suggest its cardioprotective efficacy against DOX‑induced cardiotoxicity through mitochondrial protection, the modulation of key signaling pathways and the inhibition of apoptosis. The present review aimed to provide a comprehen‑ sive overview of the mechanisms of action of visnagin, as well as to provide experimental evidence, and potential integration into cancer treatment regimens, highlighting its promise as a novel therapeutic agent for managing cardiotoxicity in patients undergoing anthracycline chemotherapy.
{"title":"Visnagin: A novel cardioprotective agent against anthracycline toxicity (Review)","authors":"Omar Obeidat, Ali Obeidat, Abedallah Obeidat, Mohamed Ismail","doi":"10.3892/mi.2024.161","DOIUrl":"https://doi.org/10.3892/mi.2024.161","url":null,"abstract":". Doxorubicin (DOX), a cornerstone of cancer chemotherapy, is marred by its dose‑dependent cardiotoxicity, leading to cardiomyopathy and heart failure. The epidemi‑ ology of DOX‑related cardiotoxicity highlights its cumulative, progressive nature, with a significant impact on the health of patients. The pathophysiological mechanisms involve mitochondrial dysfunction, oxidative stress and disrupted calcium homeostasis in cardiomyocytes. Despite the search for effective cardioprotective strategies, current treatments offer limited efficacy. Visnagin emerges as a potential solution, known for its vasodilatory and anti‑inflammatory properties, and recent studies suggest its cardioprotective efficacy against DOX‑induced cardiotoxicity through mitochondrial protection, the modulation of key signaling pathways and the inhibition of apoptosis. The present review aimed to provide a comprehen‑ sive overview of the mechanisms of action of visnagin, as well as to provide experimental evidence, and potential integration into cancer treatment regimens, highlighting its promise as a novel therapeutic agent for managing cardiotoxicity in patients undergoing anthracycline chemotherapy.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"120 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140985371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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