Pub Date : 2023-09-14DOI: 10.1186/s12301-023-00378-y
Shashank Singh, Sajad Ahmad Para, Mohammad Saleem Wani, Faiz Manzar, Manjul Kumar
Abstract Background We intended to assess the role of POPVESL scoring system in managing renal pseudoaneurysm at our institute which is a referral center in this region. Methods We retrospectively reviewed the records of all patients who were managed for renal pseudoaneurysm between January 2020 and December 2022. Data were collected from patient medical records and analyzed by using SPSS Statistics for Windows version 29.0. Data were expressed as mean ± standard deviation (SD) or median for continuous variables, whereas frequency and percentage were used to express qualitative data. Demographic data, type of procedure, operative data, post-procedure data of patients, management type, i.e., conservative or angioembolization were recorded and POPVESL score of individual patients was calculated. Data analysis was conducted among subgroups based on management type, i.e., conservative vs angioembolization. ROC curves were utilized to find the threshold value for predicting the need of angioembolization. Results Out of 55, pseudoaneurysm develops after USG guided PCN in 4 individuals, i.e., 7.3%; renal biopsy in 11, i.e., 20% and PCNL in 40, i.e., 72.7%. On statistical analysis, hemoglobin drop, number of PCV transfused, size of vascular lesion and interval of readmission showed significant differences among subgroups and were predictive of the need for angioembolization. There was a significant difference in POPVESL score between both subgroups. POPVESL score 11 and above is 100% specific and 90% sensitive for angioembolization. Conclusion Renal pseudoaneurysm with a low POPVESL (i.e., < 11) score can be managed conservatively. This scoring system has the potential to help in making bedside decision for managing intrarenal vascular bleeding.
背景:本研究旨在评估POPVESL评分系统在本地区转诊中心治疗肾假性动脉瘤中的作用。方法回顾性分析2020年1月至2022年12月期间所有接受肾假性动脉瘤治疗的患者的记录。数据来源于患者病历，使用SPSS Statistics for Windows version 29.0进行分析。连续变量用均数±标准差(SD)或中位数表示，定性数据用频率和百分比表示。记录患者的人口学资料、手术类型、手术资料、术后资料、治疗方式(保守或血管栓塞)，并计算个体患者的POPVESL评分。根据治疗方式，即保守治疗与血管栓塞治疗，对亚组进行数据分析。利用ROC曲线寻找预测血管栓塞必要性的阈值。结果55例患者中，USG引导下PCN术后假性动脉瘤发生4例，占7.3%;肾活检11例，占20%;PCNL 40例，占72.7%。经统计分析，亚组间血红蛋白下降、输注PCV次数、血管病变大小、再入院间隔有显著性差异，可预测是否需要血管栓塞。两组间POPVESL评分差异有统计学意义。POPVESL评分11分及以上对血管栓塞的特异性为100%，敏感性为90%。结论肾假性动脉瘤伴低POPVESL(即<11)评分可以保守管理。该评分系统有潜力帮助床边决定如何处理肾内血管出血。
{"title":"Utility of POPVESL scoring system in the management of renal pseudoaneurysm: a retrospective study","authors":"Shashank Singh, Sajad Ahmad Para, Mohammad Saleem Wani, Faiz Manzar, Manjul Kumar","doi":"10.1186/s12301-023-00378-y","DOIUrl":"https://doi.org/10.1186/s12301-023-00378-y","url":null,"abstract":"Abstract Background We intended to assess the role of POPVESL scoring system in managing renal pseudoaneurysm at our institute which is a referral center in this region. Methods We retrospectively reviewed the records of all patients who were managed for renal pseudoaneurysm between January 2020 and December 2022. Data were collected from patient medical records and analyzed by using SPSS Statistics for Windows version 29.0. Data were expressed as mean ± standard deviation (SD) or median for continuous variables, whereas frequency and percentage were used to express qualitative data. Demographic data, type of procedure, operative data, post-procedure data of patients, management type, i.e., conservative or angioembolization were recorded and POPVESL score of individual patients was calculated. Data analysis was conducted among subgroups based on management type, i.e., conservative vs angioembolization. ROC curves were utilized to find the threshold value for predicting the need of angioembolization. Results Out of 55, pseudoaneurysm develops after USG guided PCN in 4 individuals, i.e., 7.3%; renal biopsy in 11, i.e., 20% and PCNL in 40, i.e., 72.7%. On statistical analysis, hemoglobin drop, number of PCV transfused, size of vascular lesion and interval of readmission showed significant differences among subgroups and were predictive of the need for angioembolization. There was a significant difference in POPVESL score between both subgroups. POPVESL score 11 and above is 100% specific and 90% sensitive for angioembolization. Conclusion Renal pseudoaneurysm with a low POPVESL (i.e., < 11) score can be managed conservatively. This scoring system has the potential to help in making bedside decision for managing intrarenal vascular bleeding.","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134912772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background Infertility is a major health problem that affects 7% of the men’s population. Oxidative stress (OS) plays a significant role in the pathophysiology of male infertility. The purpose of this study comparatively evaluated the total anti-oxidation status and DNA/chromatin integrity in semen samples among different infertile men’s groups compared with the normozoospermic men. Methods This cross-sectional study contains four experimental groups, including teratozoospermia (Exp I), asthenoteratozoospermia (Exp II), oligoasthenoteratozoospermia (Exp III), and azoospermia (Exp IV), as well as the control group of normozoospermic men. The total antioxidant capacity (TAC) and total oxidant status (TOS) were assessed by applying the enzyme-linked immunosorbent assay. The chromatin/DNA damage was assessed in semen samples of all study groups by applying chromomycin A3 (CMA3) and toluidine blue (TB) staining methods. Results The results showed significantly higher proportions of TB+ and CMA3 positive sperm in all experimental groups compared to controls ( P < 0.001). TAC, TOS, and the ratio of TAC to TOS were significantly different in all experimental groups compared to the normozoospermic men ( P < 0.001). Conclusion Our study demonstrated that at least one sperm parameter abnormality, such as teratozoospermia could cause serious defects at the levels of DNA/chromatin as well as the antioxidants to oxidant balance of human spermatozoa in subfertile men with abnormal spermogram. Infertile men with sperm morphological abnormalities may benefit from simultaneous assessment of sperm DNA defects and OS.
{"title":"Effects of adverse semen parameters on total oxidation status and DNA/chromatin integrity","authors":"Maryam Imani, Minoo Vahedi Raad, Maliheh Afsari, Farzaneh Fesahat","doi":"10.1186/s12301-023-00377-z","DOIUrl":"https://doi.org/10.1186/s12301-023-00377-z","url":null,"abstract":"Abstract Background Infertility is a major health problem that affects 7% of the men’s population. Oxidative stress (OS) plays a significant role in the pathophysiology of male infertility. The purpose of this study comparatively evaluated the total anti-oxidation status and DNA/chromatin integrity in semen samples among different infertile men’s groups compared with the normozoospermic men. Methods This cross-sectional study contains four experimental groups, including teratozoospermia (Exp I), asthenoteratozoospermia (Exp II), oligoasthenoteratozoospermia (Exp III), and azoospermia (Exp IV), as well as the control group of normozoospermic men. The total antioxidant capacity (TAC) and total oxidant status (TOS) were assessed by applying the enzyme-linked immunosorbent assay. The chromatin/DNA damage was assessed in semen samples of all study groups by applying chromomycin A3 (CMA3) and toluidine blue (TB) staining methods. Results The results showed significantly higher proportions of TB+ and CMA3 positive sperm in all experimental groups compared to controls ( P < 0.001). TAC, TOS, and the ratio of TAC to TOS were significantly different in all experimental groups compared to the normozoospermic men ( P < 0.001). Conclusion Our study demonstrated that at least one sperm parameter abnormality, such as teratozoospermia could cause serious defects at the levels of DNA/chromatin as well as the antioxidants to oxidant balance of human spermatozoa in subfertile men with abnormal spermogram. Infertile men with sperm morphological abnormalities may benefit from simultaneous assessment of sperm DNA defects and OS.","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":"156 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135742223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-11DOI: 10.1186/s12301-023-00374-2
A. Basiri, Hossein Salehi Omran, M. Zahir, N. Shakhssalim, N. Borumandnia, G. Noghabaei, M. Parvin
{"title":"Partial versus radical nephrectomy in pT2a renal cell carcinoma tumors: which is the superior surgical approach?","authors":"A. Basiri, Hossein Salehi Omran, M. Zahir, N. Shakhssalim, N. Borumandnia, G. Noghabaei, M. Parvin","doi":"10.1186/s12301-023-00374-2","DOIUrl":"https://doi.org/10.1186/s12301-023-00374-2","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49507939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-09DOI: 10.1186/s12301-023-00373-3
O. Can, Kenan Sabuncu, M. Erkoç, M. Bozkurt, E. Danis, R. B. Değirmentepe, A. Ötünçtemur
{"title":"Chronic kidney disease following nephrectomy for renal tumours: retrospective analysis risk factors","authors":"O. Can, Kenan Sabuncu, M. Erkoç, M. Bozkurt, E. Danis, R. B. Değirmentepe, A. Ötünçtemur","doi":"10.1186/s12301-023-00373-3","DOIUrl":"https://doi.org/10.1186/s12301-023-00373-3","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44167021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-05DOI: 10.1186/s12301-023-00372-4
C. Okwor, I. Nnakenyi, E. Agbo, Martin N Nweke
{"title":"Sensitivity and specificity of prostate-specific antigen and its surrogates towards the detection of prostate cancer in sub-Saharan Africa: a systematic review with meta-analysis","authors":"C. Okwor, I. Nnakenyi, E. Agbo, Martin N Nweke","doi":"10.1186/s12301-023-00372-4","DOIUrl":"https://doi.org/10.1186/s12301-023-00372-4","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41479038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.1186/s12301-023-00371-5
S. Jdiaa, J. Degheili, C. Matar, Michele Mocadie, Chirine S. Khaled, A. El Zakhem
{"title":"Acute kidney injury secondary to obstructive bladder malakoplakia: a case report","authors":"S. Jdiaa, J. Degheili, C. Matar, Michele Mocadie, Chirine S. Khaled, A. El Zakhem","doi":"10.1186/s12301-023-00371-5","DOIUrl":"https://doi.org/10.1186/s12301-023-00371-5","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44337869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-19DOI: 10.1186/s12301-023-00368-0
K. Kapoor, Anup Kumar
{"title":"3D-Laparoscopic transperitoneal pyelolithotomy in a rare case of pelvic cake kidney: case report and review of literature","authors":"K. Kapoor, Anup Kumar","doi":"10.1186/s12301-023-00368-0","DOIUrl":"https://doi.org/10.1186/s12301-023-00368-0","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49325444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-19DOI: 10.1186/s12301-023-00370-6
A. Ouattara, A. Paré, M. Konaté, D. Yé, Mohamed Simporé, B. Kirakoya, F. A. Kaboré, T. Kambou
{"title":"Penile fracture in burkina faso: our experience on the management of 21 cases","authors":"A. Ouattara, A. Paré, M. Konaté, D. Yé, Mohamed Simporé, B. Kirakoya, F. A. Kaboré, T. Kambou","doi":"10.1186/s12301-023-00370-6","DOIUrl":"https://doi.org/10.1186/s12301-023-00370-6","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48718379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-17DOI: 10.1186/s12301-023-00369-z
Prof. Dr. Hesham N. Mustafa
{"title":"Ameliorative potential of the quercetin on lead-induced testicular damage: morphohistometric and biochemical analysis","authors":"Prof. Dr. Hesham N. Mustafa","doi":"10.1186/s12301-023-00369-z","DOIUrl":"https://doi.org/10.1186/s12301-023-00369-z","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49101214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-17DOI: 10.1186/s12301-023-00367-1
Daniela I. Mateescu, Hamdi Dahir, A. Goel, E. Ray, S. Madaan
{"title":"Urinary bladder melanosis with complete resolution case report","authors":"Daniela I. Mateescu, Hamdi Dahir, A. Goel, E. Ray, S. Madaan","doi":"10.1186/s12301-023-00367-1","DOIUrl":"https://doi.org/10.1186/s12301-023-00367-1","url":null,"abstract":"","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49492327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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