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Congenital Hydrocephalus and Associated Risk Factors: An Institution-Based Case–Control Study, Dessie Town, North East Ethiopia 先天性脑积水及其相关危险因素:埃塞俄比亚东北部德西镇一项基于机构的病例对照研究
Q2 PEDIATRICS Pub Date : 2022-05-01 DOI: 10.2147/PHMT.S364447
M. Abebe, G. Seyoum, Bahru Emamu, Demissie Teshome
Introduction Congenital hydrocephalus is one of the commonest congenital anomalies of the central nervous system. It is characterized by extensive accumulation of cerebrospinal fluid within the ventricles of the brain due to an imbalance between synthesis and absorption of cerebrospinal fluid. This study was planned to investigate the incidence and associated risk factors of congenital hydrocephalus. Methods Unmatched case–control study was conducted in 34 (cases) and 104 (controls) pregnant women. Maternal data were collected from a structured questionnaire, and fetal-related data were recorded from obstetric ultrasound. Epi-info 7 and SPSS version 24 were used for data entry and analysis, respectively. The association between congenital hydrocephalus and risk factors was evaluated using binary logistic regression. Results The incidence of congenital hydrocephalus was 2.67 per 1000 pregnancies. The result of multivariate logistic regression indicated that alcohol use and iron with folic acid supplementation during pregnancy were significantly associated with the development of congenital hydrocephalus (OR: 7.64, 95% CI: 1.97–29.66 and p-value: 0.003 and OR: 0.186, 95% CI: 0.07–0.49 and p-value: 0.001, respectively). Maternal exposure to typhus and typhoid and use of antibiotics during early pregnancy were also significantly associated with congenital hydrocephalus. Moreover, significant association was also observed between the simultaneous development of spina bifida and congenital hydrocephalus (p-value 0.03). Conclusion In conclusion, alcohol consumption, unprescribed use of antibiotics and infection during pregnancy as well as absence of folic acid supplementation may predispose to congenital hydrocephalus.
先天性脑积水是中枢神经系统最常见的先天性异常之一。其特征是由于脑脊液的合成和吸收之间的不平衡,脑脊液在脑室内大量积聚。本研究旨在调查先天性脑积水的发病率及相关危险因素。方法对34例(病例)和104例(对照)孕妇进行非匹配病例对照研究。从结构化问卷中收集产妇数据,并从产科超声中记录胎儿相关数据。Epi-info 7和SPSS 24分别用于数据输入和分析。先天性脑积水与危险因素之间的关系采用二元逻辑回归进行评估。结果先天性脑积水的发生率为2.67/1000例。多元逻辑回归结果表明,妊娠期间饮酒和补充叶酸的铁与先天性脑积水的发生显著相关(OR:7.64,95%CI:1.97-29.66,p值:0.003,OR:0.186,95%CI:0.07–0.49,p值0.001)。母亲在怀孕早期接触伤寒和伤寒以及使用抗生素也与先天性脑积水显著相关。此外,同时发生脊柱裂和先天性脑积水之间也存在显著相关性(p值0.03)。
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引用次数: 4
Physical Activity Interventions in Children with Juvenile Idiopathic Arthritis: A Systematic Review of Randomized Controlled Trials 青少年特发性关节炎儿童的体育活动干预:随机对照试验的系统评价
Q2 PEDIATRICS Pub Date : 2022-04-01 DOI: 10.2147/PHMT.S282611
M. Iversen, M. André, J. von Heideken
Introduction Children with juvenile arthritis (JA) experience pain, stiffness, fatigue, and decreased motion leading to difficulties with daily activities and low physical activity (PA). PA is critical to improve health and function and mitigate JA-associated symptoms. This study evaluated the evidence for PA interventions in children with JA. Materials and Methods A systematic review of randomized controlled trials (RCTs) of PA interventions in children with JA was conducted. Ovid (Medline), Cochrane Library, EMBASE, and CINAHL databases were searched for papers published in English between 1/1/1946 and 9/1/2021. Studies which concurrently assessed medical interventions were excluded. Participant and intervention characteristics and outcomes were extracted. Study internal validity and intervention attributes were assessed. Results A total of 555 studies were identified, with 13 studies from 10 countries included. Data from 672 children diagnosed with juvenile idiopathic arthritis (JIA) (range of mean ages, 8.7 to 16.1 years) were analyzed. Fifty-two percent of intervention arms incorporated strengthening exercise alone or combined with other exercise, with 61.9% performed 3x/week. About 43.5% of sessions lasted >45 to ≤60 minutes and 65.2% of programs were ≥12 to <28 weeks. PA interventions improved function and symptoms without adverse events. Intervention details were missing especially regarding PA intensity, reasons for dropouts, and adherence. Only two studies incorporated strategies to promote adherence. Discussion RCTs of PA interventions in JA only include JIA. Available RCTs used mixed modes of interventions. Reporting of PA interventions lacks sufficient detail to discern the dose-response relationship. Strategies to motivate engagement in PA and to support families to promote PA are lacking, as are studies of long-term outcomes. Conclusion There are limited RCTs of PA interventions in JIA. Adherence was better with low intensity programs. PA interventions for JIA yield positive health benefits but better reporting of PA intervention details is needed to generate more high-quality evidence and inform clinical practice. Prospero Registration Maura Iversen, Johan von Heideken, Marie Andre. Physical Activity in Children with Rheumatic Diseases: a systematic review. PROSPERO 2021 CRD42021274634 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274634.
引言患有幼年关节炎(JA)的儿童会经历疼痛、僵硬、疲劳和运动减少,导致日常活动困难和体力活动不足(PA)。PA对改善健康和功能以及缓解JA相关症状至关重要。本研究评估了PA干预JA儿童的证据。材料与方法对JA患儿PA干预的随机对照试验(RCTs)进行系统回顾。检索Ovid(Medline)、Cochrane图书馆、EMBASE和CINAHL数据库中1946年1月1日至2021年9月1日期间以英语发表的论文。同时评估医疗干预措施的研究被排除在外。提取参与者和干预的特征和结果。评估了研究的内部有效性和干预属性。结果共确定555项研究,其中包括来自10个国家的13项研究。分析了672名被诊断为青少年特发性关节炎(JIA)的儿童(平均年龄范围为8.7至16.1岁)的数据。52%的干预组将强化运动单独或与其他运动相结合,61.9%的干预组每周进行3次。约43.5%的疗程持续时间>45至≤60分钟,65.2%的疗程≥12至<28周。PA干预改善了功能和症状,没有出现不良事件。干预细节缺失,尤其是在PA强度、辍学原因和依从性方面。只有两项研究纳入了促进依从性的策略。讨论PA干预JA的随机对照试验仅包括JIA。现有的随机对照试验采用了混合干预模式。PA干预措施的报告缺乏足够的细节来辨别剂量-反应关系。缺乏激励参与PA和支持家庭促进PA的策略,也缺乏对长期结果的研究。结论JIA患者PA干预的随机对照试验有限。低强度项目的依从性更好。对JIA的PA干预产生了积极的健康益处,但需要更好地报告PA干预细节,以产生更多高质量的证据并为临床实践提供信息。Prospero Registration Maura Iversen,Johan von Heidken,Marie Andre。类风湿性疾病儿童的体育活动:一项系统综述。PROSPERO 2021 CRD42021274634可从以下网站获得:https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274634.
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引用次数: 3
Treatment Outcome and Associated Factors of Acute Malnutrition Among Children in the Therapeutic Feeding Center of Public Hospitals in Addis Ababa, Ethiopia: An Institutional-Based Cross-Sectional Study 埃塞俄比亚亚的斯亚贝巴公立医院治疗性喂养中心儿童急性营养不良的治疗结果和相关因素:一项基于机构的横断面研究
Q2 PEDIATRICS Pub Date : 2022-04-01 DOI: 10.2147/PHMT.S296979
Melat Mezemir, Meskerem Girma, D. Bekele
Background Severe acute malnutrition is the most prevalent reason for admission to a pediatric unit, and it is a leading cause of mortality in many countries, including Ethiopia, at 25% to 30%, where it affects both developed and developing countries. The objective of this study was to assess treatment outcomes and associated factors among children aged 6–59 months with severe acute malnutrition. Methods A cross-sectional study was conducted using secondary data from medical records of patients enrolled in the therapeutic feeding center from January 2016 to March 2019. There were 385 samples collected at 3 public referral hospitals in Addis Ababa, which were selected by simple random sampling. A structured questionnaire was used to collect data from the available individual folders and registers. The data analysis was performed using binary and multivariable logistic regression models. The odds ratio with 95% CI was used to identify predictor variables. Variables that have a p-value <0.05 were considered significant. Results Children who had tuberculosis were 79% less likely to recover than those who had no tuberculosis. In this study, deaths accounted for 9.1%, recovered were 72.2%, and defaulters accounted for 11.6% with a mean length of stay of 18.6 (CI: 16.9, 20.2) days and an average weight gain of 7.2 g/kg/day (CI: 5.7, 8.2). Conclusion Treating comorbidities on time can help children to recover early and reduce readmission. Integration of severe acute malnutrition screening into all service delivery points can help early identification and treatment. In the meantime, treating them with ready-to-use therapeutic feeding has a significant change in recovery.
背景严重急性营养不良是进入儿科病房的最常见原因,也是包括埃塞俄比亚在内的许多国家死亡率的主要原因,死亡率为25%至30%,发达国家和发展中国家都受到影响。本研究的目的是评估6–59个月严重急性营养不良儿童的治疗结果和相关因素。方法使用2016年1月至2019年3月在治疗性喂养中心登记的患者的医疗记录中的二级数据进行横断面研究。在亚的斯亚贝巴的3家公立转诊医院收集了385份样本,这些样本是通过简单随机抽样选出的。使用结构化调查表从现有的个人文件夹和登记册中收集数据。使用二元和多变量逻辑回归模型进行数据分析。95%置信区间的比值比用于确定预测变量。p值<0.05的变量被认为是显著的。结果有肺结核的儿童康复的可能性比没有肺结核的低79%。在本研究中,死亡占9.1%,康复占72.2%,违约者占11.6%,平均住院时间18.6天(CI:116.9,20.2),平均体重增加7.2g/kg/天(CI:5.7,8.2)。将严重急性营养不良筛查纳入所有服务提供点有助于早期识别和治疗。与此同时,用现成的治疗性喂养对它们的恢复有着显著的变化。
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引用次数: 0
Rational Dispensing of Oral Dosage Forms of Medicines to Children and Its Associated Factors in South West Ethiopia 埃塞俄比亚西南部儿童口服剂型的合理分配及其相关因素
Q2 PEDIATRICS Pub Date : 2022-04-01 DOI: 10.2147/PHMT.S360383
Fikadu Ejeta, Diriba Feyisa, Temesgen Aferu, Jafer Siraj, Demeke Melkam, Ahmed Ali
Introduction Obstacles encountered when maintaining excellent dispensing practices for children include a lack of age-appropriate dosage forms, a shortage of medications in appropriate strengths for children, a lack of appetizing drugs, and a lack of competence in pediatric pharmacy. These difficulties contribute to ineffective dispensing procedures and an urgent need to study whether oral dose forms of medications are dispensed to children in a rational way. Objective The purpose of this study is to evaluate the rational dispensing of oral dosage forms of medicines to children, as well as the factors that influence this practice. Methods Using validated indicators, a cross-sectional study design was utilized to analyze the rational dispensing practice of oral dosage forms of medicines administered to children under the age of 12 years in seven pharmacies and two drug stores over a one-month period. Results and discussions Out of 810 medicines, 11.7% and 4% were irrationally manipulated, 5.8% and 1.8% needed manipulation, 3.7% and 0.2% were alternatively dispensed, 8.8% and 7.5% of the medicines had correct advice on their label and also 745 medicines were adequately labeled in the hospital and the selected drug stores. In this study, 92% of medicines were adequately labeled and had sufficient advice on their labels, 15.3% of medicines were irrationally manipulated and around 7.7% of the dosage forms needed manipulation during dispensing. The type of medicine retail outlet had a significant effect on the percentage of instances where alternative solid oral dosage forms were dispensed (p = 0.003), the percentage of dosage forms were adequately labeled (p = 0.008), and the percentage of dosage forms were irrationally manipulated before dispensing (p = 0.001). Conclusion The rational dispensing practice of oral dosage forms of medicines was relatively poor and there is room for improvement.
引言在为儿童保持良好的配药实践时遇到的障碍包括缺乏适合年龄的剂型、缺乏适合儿童服用的适当强度的药物、缺乏开胃药以及缺乏儿科药学能力。这些困难导致配药程序无效,迫切需要研究是否以合理的方式向儿童配药。目的本研究旨在评估儿童口服剂型的合理分配,以及影响这种做法的因素。方法采用经验证的指标,采用横断面研究设计,分析7家药店和2家药店一个月内12岁以下儿童口服剂型药物的合理配药实践。结果和讨论在810种药物中,11.7%和4%被非理性操纵,5.8%和1.8%需要操纵,3.7%和0.2%被交替分配,8.8%和7.5%的药物标签上有正确的建议,745种药物在医院和选定的药店有充分的标签。在这项研究中,92%的药物都有充分的标签,标签上有足够的建议,15.3%的药物被非理性地操纵,大约7.7%的剂型在配药过程中需要操纵。药品零售店的类型对分配替代固体口服剂型的情况百分比有显著影响(p=0.003)、剂型被充分标记的百分比(p=0.008),结论口服剂型的合理配药实践相对较差,还有改进的空间。
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引用次数: 0
Necrotizing Enterocolitis and Its Predictors Among Preterm Neonates Admitted in Neonatal Intensive Care Units of Gurage Zone Public Hospitals, Southwest Ethiopia, 2021 2021年埃塞俄比亚西南部古拉奇地区公立医院新生儿重症监护室收治的早产儿坏死性小肠结肠炎及其预测因素
Q2 PEDIATRICS Pub Date : 2022-03-01 DOI: 10.2147/PHMT.S353663
Bogale Chekole Temere, Agerie Aynalem Mewahegn, Bitew Tefera Zewudie, Fisha Alebel GebreEyesus, Amare Kassaw, Belete Gelaw Walle, Shegaw Geze Tenaw, Yibeltal Mesfin, Muche Argaw, Haymanot Abebe, Shegaw Tesfa, Netsanet Habte, Robel Birhanu, Wesila Seid
Background Necrotizing Enter colitis (NEC) is the most common multifactorial and devastating gastrointestinal emergency which primarily affects premature infants. The purpose of this study was to identify the prevalence of Necrotizing Enterocolitis and its associated factors among preterm neonates admitted to Neonatal Intensive Care Units in Gurage Zone hospitals. Methods Institution-based cross-sectional study design was employed. The simple Random Sampling Technique was applied to collect the data using a structured questionnaire. Data were cleaned, checked for inconsistencies, coded and entered via EPI data 3.1, and exported to Stata version 14 for further analysis. The data were processed by Stata 14 to estimate the prevalence of necrotizing enterocolitis. Results The prevalence of Necrotizing Enterocolitis among neonates was 28 (9.7%) 95% CI of 6. 8–13.7%. Birth weight (AOR: 7.33 95% CI (2.04: 26.38)), presence of maternal infection (AOR: 6.09, 95% CI (1.31:28.26)), length of hospital stay (AOR: 3.28, 95% CI (1.20, 8.96)), and initiating trophic feeding (AOR: 5.89, 95% CI (2.27: 15.33)) were associated with neonatal necrotizing enterocolitis. Conclusion The prevalence of Necrotizing Enterocolitis among preterm neonates was significant and special attention is needed for premature neonates with low birth weight and born from mothers with infection during pregnancy. Minimizing the length of hospital stay will be very useful to prevent the occurrence of Necrotizing Enterocolitis.
背景坏死性肠炎(NEC)是最常见的多因素和破坏性胃肠道急症,主要影响早产儿。本研究的目的是确定坏死性小肠结肠炎的患病率及其相关因素在住在古拉格地区医院新生儿重症监护病房的早产儿。方法采用基于机构的横断面研究设计。采用简单随机抽样法,采用结构化问卷收集数据。数据被清理,检查不一致,通过EPI数据3.1进行编码和输入,并导出到Stata版本14进行进一步分析。数据经Stata 14处理,以估计坏死性小肠结肠炎的患病率。结果新生儿坏死性小肠结肠炎患病率为28 (9.7%),95% CI为6。8 - 13.7%。出生体重(AOR: 7.33 95% CI(2.04: 26.38))、母体感染(AOR: 6.09, 95% CI(1.31:28.26))、住院时间(AOR: 3.28, 95% CI(1.20, 8.96))和开始营养喂养(AOR: 5.89, 95% CI(2.27: 15.33))与新生儿坏死性小肠结肠炎相关。结论新生儿坏死性小肠结肠炎患病率较高,对低出生体重及妊娠期感染母亲所生的早产儿应给予特别关注。缩短住院时间对于预防坏死性小肠结肠炎的发生是非常有用的。
{"title":"Necrotizing Enterocolitis and Its Predictors Among Preterm Neonates Admitted in Neonatal Intensive Care Units of Gurage Zone Public Hospitals, Southwest Ethiopia, 2021","authors":"Bogale Chekole Temere, Agerie Aynalem Mewahegn, Bitew Tefera Zewudie, Fisha Alebel GebreEyesus, Amare Kassaw, Belete Gelaw Walle, Shegaw Geze Tenaw, Yibeltal Mesfin, Muche Argaw, Haymanot Abebe, Shegaw Tesfa, Netsanet Habte, Robel Birhanu, Wesila Seid","doi":"10.2147/PHMT.S353663","DOIUrl":"https://doi.org/10.2147/PHMT.S353663","url":null,"abstract":"Background Necrotizing Enter colitis (NEC) is the most common multifactorial and devastating gastrointestinal emergency which primarily affects premature infants. The purpose of this study was to identify the prevalence of Necrotizing Enterocolitis and its associated factors among preterm neonates admitted to Neonatal Intensive Care Units in Gurage Zone hospitals. Methods Institution-based cross-sectional study design was employed. The simple Random Sampling Technique was applied to collect the data using a structured questionnaire. Data were cleaned, checked for inconsistencies, coded and entered via EPI data 3.1, and exported to Stata version 14 for further analysis. The data were processed by Stata 14 to estimate the prevalence of necrotizing enterocolitis. Results The prevalence of Necrotizing Enterocolitis among neonates was 28 (9.7%) 95% CI of 6. 8–13.7%. Birth weight (AOR: 7.33 95% CI (2.04: 26.38)), presence of maternal infection (AOR: 6.09, 95% CI (1.31:28.26)), length of hospital stay (AOR: 3.28, 95% CI (1.20, 8.96)), and initiating trophic feeding (AOR: 5.89, 95% CI (2.27: 15.33)) were associated with neonatal necrotizing enterocolitis. Conclusion The prevalence of Necrotizing Enterocolitis among preterm neonates was significant and special attention is needed for premature neonates with low birth weight and born from mothers with infection during pregnancy. Minimizing the length of hospital stay will be very useful to prevent the occurrence of Necrotizing Enterocolitis.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"95 - 102"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42054807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Early Newborn Bath Practice and Its Associated Factors in Jimma, South West Ethiopia, 2021 2021年,埃塞俄比亚西南部吉马的新生儿早期沐浴实践及其相关因素
Q2 PEDIATRICS Pub Date : 2022-03-01 DOI: 10.2147/PHMT.S348657
Belete Fenta Kebede, Yalemtsehay Dagnaw Genie, Aynalem Yetwale Hiwot, Tsegaw Biyazin Tesafa, Betelhem Abebe
Aims The timing of the first bath is an important variable in newborn care despite variations from setting to setting. Early first bath can affect the newborn’s temperature, blood sugar levels, bonding with his/her mother, comfort, and security. Thus, timing affects several aspects of newborn care and is still a major concern. However, in Ethiopia, there is insufficient evidence regarding newborn bath timing. Therefore, this study aimed to assess early newborn bath practice and its associated factors in Jimma, Southwest Ethiopia, 2021. Materials and Methods An institutional-based cross-sectional study was conducted from July to August 2021 on 388 postpartum women who came for newborn immunization. Data were collected through face-to-face interviews using a structured questionnaire. Data were entered into Epi-data 4.4.2.1 and exported to Stata version 14 for cleaning and analysis. Logistic regression was used to determine the association between explanatory and response variables. The level of significance was declared at a p-value of less than 0.05 in multivariable logistic regression. Results This study revealed 126 (32.5%) of mothers were practicing early newborn bathing. Vaginal mode of delivery (AOR: 3.84 (95% CI: 1.96–7.52)), poor knowledge about danger signs (AOR: 6.78 (95% CI: 3.77–12.19), poor knowledge about hypothermia (AOR: 0.35 (95% CI: 0.20–0.58) and educational level of women (AOR: 0.33 (95% CI: 0.15–0.73) were variables significantly associated with early newborn bathing practice. Conclusion Early neonatal bathing practice in this study is high and needs priority as it results in neonatal hypothermia and its complications. Therefore, Education for women and their families on delayed bathing of their newborns could begin in antenatal care visit, on admission into the labor and delivery unit and again on the postpartum unit.
目的第一次洗澡的时间是新生儿护理中的一个重要变量,尽管不同的环境会有所不同。过早的第一次洗澡会影响新生儿的体温、血糖水平、与母亲的亲密关系、舒适度和安全感。因此,时间安排影响新生儿护理的几个方面,仍然是一个主要问题。然而,在埃塞俄比亚,关于新生儿洗澡时间的证据不足。因此,本研究旨在评估2021年埃塞俄比亚西南部吉姆马的早期新生儿洗澡实践及其相关因素。材料和方法2021年7月至8月,对388名前来接受新生儿免疫接种的产后妇女进行了一项基于机构的横断面研究。数据是通过使用结构化问卷的面对面访谈收集的。将数据输入Epi数据4.4.2.1,并导出至Stata版本14进行清洁和分析。Logistic回归用于确定解释变量和反应变量之间的相关性。在多变量逻辑回归中,显著性水平的p值小于0.05。结果126名(32.5%)母亲在新生儿早期洗澡。阴道分娩方式(AOR:3.84(95%CI:1.96-7.52))、对危险体征知之甚少(AOR:6.78(95%CI:3.77-12.19)、对体温过低知之甚少。结论本研究中的早期新生儿沐浴实践是高度重视的,需要优先考虑,因为它会导致新生儿体温过低及其并发症。因此,对妇女及其家人关于新生儿延迟洗澡的教育可以从产前护理就诊、进入分娩和分娩单元以及产后单元开始。
{"title":"Early Newborn Bath Practice and Its Associated Factors in Jimma, South West Ethiopia, 2021","authors":"Belete Fenta Kebede, Yalemtsehay Dagnaw Genie, Aynalem Yetwale Hiwot, Tsegaw Biyazin Tesafa, Betelhem Abebe","doi":"10.2147/PHMT.S348657","DOIUrl":"https://doi.org/10.2147/PHMT.S348657","url":null,"abstract":"Aims The timing of the first bath is an important variable in newborn care despite variations from setting to setting. Early first bath can affect the newborn’s temperature, blood sugar levels, bonding with his/her mother, comfort, and security. Thus, timing affects several aspects of newborn care and is still a major concern. However, in Ethiopia, there is insufficient evidence regarding newborn bath timing. Therefore, this study aimed to assess early newborn bath practice and its associated factors in Jimma, Southwest Ethiopia, 2021. Materials and Methods An institutional-based cross-sectional study was conducted from July to August 2021 on 388 postpartum women who came for newborn immunization. Data were collected through face-to-face interviews using a structured questionnaire. Data were entered into Epi-data 4.4.2.1 and exported to Stata version 14 for cleaning and analysis. Logistic regression was used to determine the association between explanatory and response variables. The level of significance was declared at a p-value of less than 0.05 in multivariable logistic regression. Results This study revealed 126 (32.5%) of mothers were practicing early newborn bathing. Vaginal mode of delivery (AOR: 3.84 (95% CI: 1.96–7.52)), poor knowledge about danger signs (AOR: 6.78 (95% CI: 3.77–12.19), poor knowledge about hypothermia (AOR: 0.35 (95% CI: 0.20–0.58) and educational level of women (AOR: 0.33 (95% CI: 0.15–0.73) were variables significantly associated with early newborn bathing practice. Conclusion Early neonatal bathing practice in this study is high and needs priority as it results in neonatal hypothermia and its complications. Therefore, Education for women and their families on delayed bathing of their newborns could begin in antenatal care visit, on admission into the labor and delivery unit and again on the postpartum unit.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"43 - 52"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43683848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Antimicrobial Use and Management of Childhood Diarrhea at Community Drug Retail Outlets in Eastern Ethiopia: A Matched Questionnaire-Based and Simulated Patient-Case Study 埃塞俄比亚东部社区药品零售店儿童腹泻的抗菌药物使用和管理:基于匹配问卷和模拟患者案例研究
Q2 PEDIATRICS Pub Date : 2022-03-01 DOI: 10.2147/PHMT.S348204
Dumessa Edessa, M. Sisay, Bisrat Hagos, Firehiwot Amare
Introduction Antimicrobial agents have saved millions of lives worldwide. However, inappropriate use has become a global concern leading to the emergence and spread of antimicrobial resistance (AMR). In this regard, the dispensing practices of pharmacy professionals in the community drug retail outlets (CDROs) plays a central role. Therefore, this study was aimed to assess the knowledge and dispensing practices of pharmacy professionals in the management of childhood diarrhea in CDROs of Eastern Ethiopia. Methods A community based cross-sectional study was conducted in 100 randomly selected CDROs in Eastern Ethiopia from 1 August to 30 September 2020. Data were collected with a structured questionnaire matched with a simulated patient case. Descriptive statistics were employed to summarize variables. Cohen’s Kappa was analyzed to measure the degree of agreement between questionnaire-based and simulated patient-based methods. Binary logistic regression analysis was conducted to determine factors associated with inappropriate dispensing practice. Results Majority of the participants were aged 25–34 years (median: 29 years). High proportion of them were male (65%) and had work experiences of two or more years. Majority (61%) of the professionals were knowledgeable about AMR. Out of 2886 scores, 745 scores were agreed on Cohen’s Kappa interrater agreement scale with the overall percent agreement between the two methods being 26.0%. Besides, about 67% of dispensing practices to the simulated patient case was found inappropriate. On the multivariate analysis, insufficient knowledge of retailers on AMR was significantly associated with the inappropriate dispensing of antimicrobial agents. Conclusion A considerable proportion of retailers had insufficient knowledge regarding the emergence and spread of AMR. Only a quarter of their questionnaire-based knowledge response agreed with simulated-patient-based actual practice, indicating weak agreement between the two methods and high level of inappropriate practice. Besides, insufficient knowledge of retailers was significantly associated with their inappropriate dispensing of antimicrobials.
引言抗菌剂拯救了全世界数百万人的生命。然而,不当使用已成为全球关注的问题,导致抗微生物耐药性(AMR)的出现和传播。在这方面,社区药品零售店药房专业人员的配药实践发挥着核心作用。因此,本研究旨在评估药房专业人员在埃塞俄比亚东部CDRO儿童腹泻管理方面的知识和配药实践。方法于2020年8月1日至9月30日在埃塞俄比亚东部随机选择的100名CDRO中进行了一项基于社区的横断面研究。数据是通过与模拟患者病例相匹配的结构化问卷收集的。采用描述性统计对变量进行汇总。对Cohen的Kappa进行分析,以衡量基于问卷的方法和基于模拟患者的方法之间的一致程度。进行二元逻辑回归分析,以确定与不适当配药实践相关的因素。结果大多数参与者年龄在25-34岁(中位数:29岁)。他们中有很大一部分是男性(65%),有两年或两年以上的工作经验。大多数(61%)专业人员了解AMR。在2886分中,745分在Cohen的Kappa跨评估者一致性量表上达成一致,两种方法之间的总体一致率为26.0%。此外,约67%的模拟患者病例配药实践被发现不合适。在多变量分析中,零售商对AMR的了解不足与抗菌药物分配不当显著相关。结论相当一部分零售商对AMR的出现和传播知之甚少。只有四分之一的基于问卷的知识回答与基于模拟患者的实际实践一致,这表明两种方法之间的一致性较弱,不适当的实践水平很高。此外,对零售商的了解不足与他们不恰当地分配抗菌药物有很大关系。
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引用次数: 3
Lifespan and Associated Factors of Peripheral Intravenous Cannula Among Hospitalized Children in Public Hospitals of the Gurage Zone, Ethiopia, 2021 2021年,埃塞俄比亚古拉奇地区公立医院住院儿童外周静脉插管的寿命和相关因素
Q2 PEDIATRICS Pub Date : 2022-03-01 DOI: 10.2147/PHMT.S351759
Agerie Aynalem Mewahegn, Betelhem Tadesse, F. GebreEyesus, T. Tarekegn, Baye Tsegaye Amlak, Mamo Solomon Emeria, B. Temere, T. Terefe, B. T. Zewudie, Haymanot Abebe Geletie, S. Mengist
Background Peripheral intravenous cannulas are routinely used in hospital-admitted children requiring intravenous therapy. The majority of peripheral IVC lines are removed before completion of therapy due to cannula complications in children. Peripheral intravenous cannula securing is a painful procedure for children, so recognizing the variables associated with the peripheral intravenous cannula lifespan would help decrease the complications and increase the duration of cannula patency. Objective The main aim of this study was to determine the lifespan and associated factors of peripheral intravenous cannula among hospitalized children in Gurage zone public hospitals, Ethiopia, 2021. Methods We conducted an institution-based cross-sectional study design among 422 admitted children in public hospitals of the Gurage zone using a systematic random sampling technique. We collected data from interviews of parents using structured questionnaires and direct observations using checklists. The data was coded and entered into EPI-DATA version 3.1 and exported to SPSS version 25 for analysis. Bivariable and multivariable analysis was used by using a binary logistic regression model. Finally, the variables with a p-value of <0.05 with a 95% confidence interval (CI) from the multivariable analysis were considered statistically significant. Results One hundred and sixty-six children (41.4%) had a short cannula lifespan (below 30 h). Multivariable logistic regression analysis showed that neonatal intensive care unit (NICU) [AOR = 4.975; 95% CI (2.811–8.805)], reason for removal (complication) [AOR = 3.277; 95% CI (1.924–5.583)], fluid [AOR = 2.285; 95% CI (1.274–4.100)], and blood transfusion [AOR = 2.407; 95% CI (1.005–5.572)] were the statistically significant variables associated with the lifespan of a peripheral intravenous cannula. Conclusion and Recommendation The proportion of the short lifespan of the peripheral intravenous cannula was higher in hospitalized children and health care providers better to use low concentration electrolytes, low osmotic pressure, and weak alkalinity fluid. The cannula access might be the responsibility of the health-trained staff, and conserving immediate removal upon the presence of a signal that indicates a complication.
背景需要静脉注射治疗的住院儿童经常使用外周静脉插管。由于儿童套管并发症,大多数外周IVC线在治疗完成前被切除。外周静脉插管固定对儿童来说是一个痛苦的过程,因此认识到与外周静脉套管寿命相关的变量将有助于减少并发症并增加套管通畅的持续时间。目的本研究的主要目的是确定2021年埃塞俄比亚古拉奇地区公立医院住院儿童外周静脉插管的使用寿命和相关因素。方法采用系统随机抽样技术,对古拉奇地区公立医院422名住院儿童进行了基于机构的横断面研究设计。我们使用结构化问卷和检查表从家长访谈中收集数据。对数据进行编码并输入EPI-data 3.1版,然后导出到SPSS 25版进行分析。采用二元逻辑回归模型进行双变量和多变量分析。最后,多变量分析中p值<0.05且置信区间(CI)为95%的变量被认为具有统计学意义。结果一百六十六名儿童(41.4%)的插管寿命较短(30小时以下)。多变量logistic回归分析显示,新生儿重症监护室(NICU)[AOR=4.975;95%置信区间(2.811–8.805)]、手术原因(并发症)[AOR=3.277;95%可信区间(1.924–5.583)]、液体[AOR=2.285;95%置信度(1.274–4.100)]、,和输血[AOR=2.407;95%置信区间(1.005–5.572)]是与外周静脉插管寿命相关的具有统计学意义的变量。结论和建议住院儿童外周静脉插管使用寿命短的比例较高,医疗保健提供者最好使用低浓度电解质、低渗透压和弱碱性液体。套管进入可能由受过健康培训的工作人员负责,并在出现指示并发症的信号时立即取出。
{"title":"Lifespan and Associated Factors of Peripheral Intravenous Cannula Among Hospitalized Children in Public Hospitals of the Gurage Zone, Ethiopia, 2021","authors":"Agerie Aynalem Mewahegn, Betelhem Tadesse, F. GebreEyesus, T. Tarekegn, Baye Tsegaye Amlak, Mamo Solomon Emeria, B. Temere, T. Terefe, B. T. Zewudie, Haymanot Abebe Geletie, S. Mengist","doi":"10.2147/PHMT.S351759","DOIUrl":"https://doi.org/10.2147/PHMT.S351759","url":null,"abstract":"Background Peripheral intravenous cannulas are routinely used in hospital-admitted children requiring intravenous therapy. The majority of peripheral IVC lines are removed before completion of therapy due to cannula complications in children. Peripheral intravenous cannula securing is a painful procedure for children, so recognizing the variables associated with the peripheral intravenous cannula lifespan would help decrease the complications and increase the duration of cannula patency. Objective The main aim of this study was to determine the lifespan and associated factors of peripheral intravenous cannula among hospitalized children in Gurage zone public hospitals, Ethiopia, 2021. Methods We conducted an institution-based cross-sectional study design among 422 admitted children in public hospitals of the Gurage zone using a systematic random sampling technique. We collected data from interviews of parents using structured questionnaires and direct observations using checklists. The data was coded and entered into EPI-DATA version 3.1 and exported to SPSS version 25 for analysis. Bivariable and multivariable analysis was used by using a binary logistic regression model. Finally, the variables with a p-value of <0.05 with a 95% confidence interval (CI) from the multivariable analysis were considered statistically significant. Results One hundred and sixty-six children (41.4%) had a short cannula lifespan (below 30 h). Multivariable logistic regression analysis showed that neonatal intensive care unit (NICU) [AOR = 4.975; 95% CI (2.811–8.805)], reason for removal (complication) [AOR = 3.277; 95% CI (1.924–5.583)], fluid [AOR = 2.285; 95% CI (1.274–4.100)], and blood transfusion [AOR = 2.407; 95% CI (1.005–5.572)] were the statistically significant variables associated with the lifespan of a peripheral intravenous cannula. Conclusion and Recommendation The proportion of the short lifespan of the peripheral intravenous cannula was higher in hospitalized children and health care providers better to use low concentration electrolytes, low osmotic pressure, and weak alkalinity fluid. The cannula access might be the responsibility of the health-trained staff, and conserving immediate removal upon the presence of a signal that indicates a complication.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"81 - 93"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46281657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Characterization of the Difficult Peripheral IV in the Perioperative Setting: A Prospective, Observational Study of Intravenous Access for Pediatric Patients Undergoing Anesthesia. 围手术期周围静脉输注困难的特征:一项麻醉患儿静脉输注的前瞻性观察性研究。
Q2 PEDIATRICS Pub Date : 2022-01-01 DOI: 10.2147/PHMT.S358250
Grant Heydinger, Shabana Z Shafy, Colin O'Connor, Olubukola Nafiu, Joseph D Tobias, Ralph J Beltran

Background: Various criteria exist for defining difficult intravenous access (DIVA) in infants and children. The current study evaluated the factors associated with DIVA in a prospective cohort of over 1000 infants and children presenting for anesthetic care.

Methods: This was a prospective, observational study of patients aged 0 to 18 years undergoing elective surgical or radiologic procedures under general anesthesia. Prior to the initial attempt at peripheral intravenous (PIV) cannulation, the anticipated difficulty of PIV catheter placement was determined by the provider using a visual analogue scale (VAS) from 1 to 10. The number of attempts was recorded as well as the time required to achieve PIV access. DIVA was defined as requiring three or more attempts. After successful cannulation, the actual difficulty of the PIV placement was assessed by the provider and recorded using the same VAS. Patient characteristics, including age, race, body mass index (BMI), American Society of Anesthesiologists (ASA) physical classification, and history of difficult PIV placement, were evaluated as covariates.

Results: In our cohort of 1002 pediatric patients, 78% of patients were successfully cannulated in a single attempt and 91% of patients were successfully cannulated in two or fewer attempts. Factors associated with requiring three or more PIV attempts included younger age (OR 8.73; 95% CI: 3.38, 22.6 for age <1 year and OR 4.93; 95% CI: 2.05, 11.8 for age 1-3 years), higher ASA physical classification (OR 1.95; 95% CI: 1.10, 3.46 for ASA II), and prior history of difficult PIV placement (OR 3.46; 95% CI: 1.70, 7.08). BMI, racial category or gender were not independent predictors of DIVA.

Conclusion: We found that approximately 9% of patients required three or more attempts at IV placement in the operating room. Patients that required multiple PIV attempts were more likely to be younger, have a higher ASA classification or a history of difficult PIV placement.

背景:定义婴儿和儿童静脉注射困难(DIVA)的标准多种多样。目前的研究评估了1000多名接受麻醉护理的婴儿和儿童的前瞻性队列中与DIVA相关的因素。方法:这是一项前瞻性观察性研究,研究对象为0 - 18岁在全身麻醉下接受选择性手术或放射治疗的患者。在首次尝试外周静脉(PIV)插管之前,PIV导管放置的预期难度由提供者使用视觉模拟评分(VAS)从1到10确定。记录了尝试次数以及实现PIV访问所需的时间。DIVA被定义为需要三次或更多的尝试。插管成功后,由提供者评估PIV放置的实际难度,并使用相同的VAS记录。患者特征,包括年龄、种族、体重指数(BMI)、美国麻醉医师协会(ASA)身体分类和PIV放置困难史,作为协变量进行评估。结果:在1002例儿科患者队列中,78%的患者在一次尝试中成功插管,91%的患者在两次或更少的尝试中成功插管。需要三次或更多次PIV尝试的相关因素包括年龄较小(or 8.73;95% CI: 3.38,年龄为22.6。结论:我们发现大约9%的患者需要在手术室进行三次或更多次静脉滴注。需要多次PIV尝试的患者更可能是年轻的,ASA分类较高或有PIV放置困难的历史。
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引用次数: 4
Magnitude of Anemia and Undernutrition Among Primary School Children in a Setting of Mass Deworming in Central Ethiopia. 埃塞俄比亚中部大规模驱虫环境下小学生贫血和营养不良程度。
Q2 PEDIATRICS Pub Date : 2022-01-01 DOI: 10.2147/PHMT.S381467
Moges Wordofa, Dessie Abera, Abiyot Mesfin, Kassu Desta, Bineyam Taye, Aster Tsegaye

Background: Undernutrition and anemia in children continue to be a public health problem in developing countries. Besides, intestinal parasitic infection among school children is common in developing countries. World Health Organization (WHO) recommends periodic deworming of children who live in endemic areas. The aim of this study was to determine the magnitude of anemia and undernutrition among school children in a setting of mass deworming.

Methods: A cross-sectional study was conducted among 510 school children aged 5-14 years from three randomly selected governmental schools in Sululta town, central Ethiopia. Socio-demographic variables were assessed using interviewer administered structured questionnaire. Anthropometric data were obtained and analyzed using WHO Anthroplusv1.0.4. Venous blood samples were collected using EDTA vacutainers. Hemoglobin level was determined by Sysmex KX-21N automated hematology analyzer and stool samples were processed using direct wet mount, formol-ether concentration and Kato-Katz methods. Data were entered and analyzed using SPSS version 21. Logistic regression analysis was performed to determine the association of anemia and undernutrition with the independent variables.

Results: The overall magnitude of anemia was 3.7%. Among anemic individuals, 84.2% and 15.8% of participants had mild and moderate anemia, respectively. The magnitude of stunting and thinness was 16.9% and 10.8%, respectively. Of them, 18.6% of stunting and 14.5% of thinness were severe. Of factors related to undernutrition, children from large families (≥5) were less likely to be stunted (AOR=0.38, 95% CI=0.2-0.7, P=0.002) compared to small families.

Conclusion: The magnitude of anemia in the study area was considered as an insignificant public health problem and none of the socio-demographic variables of participants were significantly associated with anemia and likewise with undernutrition except for family size. Further studies are required to clearly understand the impact of mass deworming on the magnitude of anemia and undernutrition.

背景:儿童营养不良和贫血仍然是发展中国家的一个公共卫生问题。此外,学龄儿童肠道寄生虫感染在发展中国家很常见。世界卫生组织(世卫组织)建议对生活在流行地区的儿童进行定期驱虫。本研究的目的是确定在大规模驱虫的情况下,在校儿童贫血和营养不良的程度。方法:对埃塞俄比亚中部Sululta镇随机选择的三所公立学校的510名5-14岁学龄儿童进行了横断面研究。社会人口学变量采用采访者管理的结构化问卷进行评估。使用WHO Anthroplusv1.0.4获取和分析人体测量数据。采用EDTA抽真空器采集静脉血。采用Sysmex KX-21N全自动血液学分析仪检测血红蛋白水平,粪便样品采用直接湿法、甲醛-醚浓度法和Kato-Katz法处理。数据输入和分析使用SPSS版本21。进行Logistic回归分析,确定贫血和营养不良与自变量的关系。结果:总贫血程度为3.7%。在贫血个体中,84.2%和15.8%的参与者分别患有轻度和中度贫血。发育迟缓和消瘦的比例分别为16.9%和10.8%。其中,18.6%的发育迟缓和14.5%的消瘦是严重的。在与营养不良相关的因素中,大家庭(≥5人)的儿童发育迟缓的可能性低于小家庭(AOR=0.38, 95% CI=0.2-0.7, P=0.002)。结论:研究地区的贫血程度被认为是一个无关紧要的公共卫生问题,除了家庭规模外,参与者的所有社会人口变量都与贫血和营养不良无关。需要进一步的研究来清楚地了解大规模驱虫对贫血和营养不良程度的影响。
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引用次数: 0
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Pediatric health, medicine and therapeutics
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