Pub Date : 2022-06-01DOI: 10.1136/rapm-2022-esra.508
HU Yörükoğlu, Ş. Cesur, C. Aksu, A. Kuş
{"title":"B432 Opioid sparing effect of PENG block in open reduction of pediatric developmental dysplasia of the hip: a case series","authors":"HU Yörükoğlu, Ş. Cesur, C. Aksu, A. Kuş","doi":"10.1136/rapm-2022-esra.508","DOIUrl":"https://doi.org/10.1136/rapm-2022-esra.508","url":null,"abstract":"","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83710555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Due to unsanitary cord care practices, cord infections are more common and prevalent in developing countries. In settings where mortality is low, dry and clean cord care is recommended for newborns delivered in health facilities or at home. Cord care practices would directly contribute to infection in newborns, accounting for a large proportion of millions of annual neonatal deaths. This study aimed to assess the cord care practices of mothers and to identify areas for intervention. Methods An institution-based cross-sectional study was conducted among mothers of neonates who gave birth in the last six months. Systematic random sampling technique was employed to include women who visited pediatric OPD and immunization clinics. Epi data version 3.1 was used to enter the data and then exported to SPSS version 26 for analysis. The association between the outcome and independent variables was examined using binary logistic regression. The strength of the association was measured using odds ratio (OR), 95% confidence intervals (CI) and p-value. Statistical significance was declared at a p-value <0.05. Results Four hundred twenty-two mothers were participated in the study. More than half (59.2%) of the respondents had good cord care practices, while nearly half (45.3%) mothers added nothing to the cord. Factors significantly associated with good cord care practices were educational status (AOR = 4.7; 95% CI = 1.34, 7.59), ANC follow-up (AOR = 3.58; 95% CI = 1.24, 10.32), initiation of breastfeeding (AOR = 1.74; 95% CI = 1.10, 2.77), and apply anything to the cord (AOR = 3.08; 95% CI = 1.92, 4.95). Conclusion The proportion of mothers with good cord care practices was inadequate. For such a high cause of neonatal death, prevention should be the priority intervention, and improving its implementation requires further effort.
背景:由于不卫生的脐带护理做法，脐带感染在发展中国家更为常见和普遍。在死亡率低的环境中，建议对在卫生机构或家中分娩的新生儿进行干燥和清洁的脐带护理。脐带护理做法将直接导致新生儿感染，在每年数百万新生儿死亡中占很大比例。本研究旨在评估母亲的脐带护理实践，并确定需要干预的领域。方法以机构为基础的横断面研究对最近六个月内分娩的新生儿母亲进行了调查。采用系统随机抽样方法，纳入到儿科门诊和免疫门诊就诊的妇女。使用Epi数据3.1版输入数据，导出到SPSS 26版进行分析。使用二元逻辑回归检验结果与自变量之间的关联。使用比值比(OR)、95%置信区间(CI)和p值来测量相关性的强度。p值<0.05为有统计学意义。结果422名母亲参与了研究。超过一半(59.2%)的受访者有良好的脐带护理做法，而近一半(45.3%)的母亲没有添加脐带。与良好脐带护理实践显著相关的因素有:教育状况(AOR = 4.7;95% CI = 1.34, 7.59)， ANC随访(AOR = 3.58;95% CI = 1.24, 10.32)，开始母乳喂养(AOR = 1.74;95% CI = 1.10, 2.77)，并将任何东西涂在脐带上(AOR = 3.08;95% ci = 1.92, 4.95)。结论做好脐带护理的母亲比例不足。对于如此高的新生儿死亡原因，预防应是优先干预措施，改进其实施需要进一步努力。
{"title":"Umbilical Cord Care Practices and Associated Factor Among Mothers of Neonates Visiting Mizan-Tepi University Teaching Hospital Southwest Ethiopia 2021","authors":"Nigatu Dessalegn, Y. Dagnaw, K. Seid, Asrat Wolde","doi":"10.2147/PHMT.S363252","DOIUrl":"https://doi.org/10.2147/PHMT.S363252","url":null,"abstract":"Background Due to unsanitary cord care practices, cord infections are more common and prevalent in developing countries. In settings where mortality is low, dry and clean cord care is recommended for newborns delivered in health facilities or at home. Cord care practices would directly contribute to infection in newborns, accounting for a large proportion of millions of annual neonatal deaths. This study aimed to assess the cord care practices of mothers and to identify areas for intervention. Methods An institution-based cross-sectional study was conducted among mothers of neonates who gave birth in the last six months. Systematic random sampling technique was employed to include women who visited pediatric OPD and immunization clinics. Epi data version 3.1 was used to enter the data and then exported to SPSS version 26 for analysis. The association between the outcome and independent variables was examined using binary logistic regression. The strength of the association was measured using odds ratio (OR), 95% confidence intervals (CI) and p-value. Statistical significance was declared at a p-value <0.05. Results Four hundred twenty-two mothers were participated in the study. More than half (59.2%) of the respondents had good cord care practices, while nearly half (45.3%) mothers added nothing to the cord. Factors significantly associated with good cord care practices were educational status (AOR = 4.7; 95% CI = 1.34, 7.59), ANC follow-up (AOR = 3.58; 95% CI = 1.24, 10.32), initiation of breastfeeding (AOR = 1.74; 95% CI = 1.10, 2.77), and apply anything to the cord (AOR = 3.08; 95% CI = 1.92, 4.95). Conclusion The proportion of mothers with good cord care practices was inadequate. For such a high cause of neonatal death, prevention should be the priority intervention, and improving its implementation requires further effort.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"227 - 234"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47072747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Growth monitoring and promotion are one of the health priorities in assessing the growth rate of a child. Appropriate growth monitoring and promotion services enable health professionals to control growth faltering and child mortality. However, there is limited information on the growth monitoring practice of health professionals and their associated factors at public health facilities of Bahir Dar health centers. Therefore, this study aimed to assess the growth monitoring practice of health professionals and associated factors at public health facilities of Bahir Dar health centers, northwest Ethiopia. Methods Institutional-based cross-sectional study for quantitative and phenomenology for qualitative was conducted from April 15 to May 15, 2021, among 314 health professionals, in Bahir Dar town, northwest Ethiopia. Census was used. A self-administered questionnaire was employed for quantitative data. Data were cleaned and entered into Epi-info version 7.1 and exported to SPSS version 20 for further analysis, and the binary logistic regression was employed. In the bi-variable analysis, those variables with a p-value less than 0.2 were fitted to multivariable analysis. Qualitative data were analyzed by using thematic analysis. Results The overall growth monitoring practice of health professionals at Bahir Dar public health centers was 30.3%, with a response rate of 98.1. The number of participants who had at least a degree was [AOR = 3.57; 95% CI: 1.54, 8.26], health professionals who had greater than 11 years of work experience [AOR = 2.98; CI: 1.36, 6.53], those who took training [AOR = 5.11; CI: 2.20, 11.90], availability of growth monitoring equipment [AOR = 4.44; CI: 1.97, 9.98], those who had lesser workload (saw less than 25 children’s per day) [AOR = 3.02; CI: 1.16, 7.86], those who had good knowledge [AOR = 4.60; CI: 2.06, 10.31] and favorable attitude [AOR = 2.58; CI: 1.14, 5.83] were significantly associated with growth monitoring practice. Conclusion The overall growth monitoring practice among health professionals of Bahir Dar public health centers was low. Work experience, age, educational status, knowledge, attitude, workload, training, and availability of growth monitoring equipment were key predictors of growth monitoring practice among health professionals in Bahir Dar public health centers. Therefore, regular supportive supervision from the regarded body, provision of training to health professionals and fulfill growth monitoring equipment are all necessary measures to provide a better growth monitoring service.
{"title":"Growth Monitoring Practice and Associated Factors Among Health Professionals at Public Health Facilities of Bahir Dar Health Centers, Northwest Ethiopia, 2021","authors":"Migbaru Tesfa, Kedir Abdela Gonete, Yawkal Chane, Senay Yohannes","doi":"10.2147/PHMT.S355214","DOIUrl":"https://doi.org/10.2147/PHMT.S355214","url":null,"abstract":"Background Growth monitoring and promotion are one of the health priorities in assessing the growth rate of a child. Appropriate growth monitoring and promotion services enable health professionals to control growth faltering and child mortality. However, there is limited information on the growth monitoring practice of health professionals and their associated factors at public health facilities of Bahir Dar health centers. Therefore, this study aimed to assess the growth monitoring practice of health professionals and associated factors at public health facilities of Bahir Dar health centers, northwest Ethiopia. Methods Institutional-based cross-sectional study for quantitative and phenomenology for qualitative was conducted from April 15 to May 15, 2021, among 314 health professionals, in Bahir Dar town, northwest Ethiopia. Census was used. A self-administered questionnaire was employed for quantitative data. Data were cleaned and entered into Epi-info version 7.1 and exported to SPSS version 20 for further analysis, and the binary logistic regression was employed. In the bi-variable analysis, those variables with a p-value less than 0.2 were fitted to multivariable analysis. Qualitative data were analyzed by using thematic analysis. Results The overall growth monitoring practice of health professionals at Bahir Dar public health centers was 30.3%, with a response rate of 98.1. The number of participants who had at least a degree was [AOR = 3.57; 95% CI: 1.54, 8.26], health professionals who had greater than 11 years of work experience [AOR = 2.98; CI: 1.36, 6.53], those who took training [AOR = 5.11; CI: 2.20, 11.90], availability of growth monitoring equipment [AOR = 4.44; CI: 1.97, 9.98], those who had lesser workload (saw less than 25 children’s per day) [AOR = 3.02; CI: 1.16, 7.86], those who had good knowledge [AOR = 4.60; CI: 2.06, 10.31] and favorable attitude [AOR = 2.58; CI: 1.14, 5.83] were significantly associated with growth monitoring practice. Conclusion The overall growth monitoring practice among health professionals of Bahir Dar public health centers was low. Work experience, age, educational status, knowledge, attitude, workload, training, and availability of growth monitoring equipment were key predictors of growth monitoring practice among health professionals in Bahir Dar public health centers. Therefore, regular supportive supervision from the regarded body, provision of training to health professionals and fulfill growth monitoring equipment are all necessary measures to provide a better growth monitoring service.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"195 - 215"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47612501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Most previous pediatric COVID-19 studies reported milder disease in children. However, there are limited pediatric data from low-income settings. We aimed to assess the characteristics and outcomes of pediatric COVID-19 in Ethiopia. Setting St. Paul’s COVID-19 treatment center; a tertiary COVID-19 center. Pediatric care was provided in a dedicated ward but with a common ICU. Methods St. Paul’s Hospital COVID-19 cohort (SPC-19) included inpatient COVID-19 RT-PCR confirmed cases from August 2020 to January 2021. Data were extracted from case report forms attached to patient charts and completed by the clinicians. Data were uploaded into the Redcap database and exported to SPSS 20 for analysis. Binary logistic regression and chi-square test were used in the analysis. Results Seventy-nine patients 0–19 years were included from the SPC-19 cohort over 6 months. Pediatric admissions accounted for 11% of cases in the cohort. The mean age (SD) was 6.9 (±6.36) years and 40 (50.6%) were female. The disease was asymptomatic or mild in 57 (72.2%), moderate in 15 (19%), and severe or critical in 7 (8.8%). The commonest presentations in symptomatic children were prostration (26.6%) followed by vomiting (12.7%), fever and cough (11.4% each), and dyspnea (10%). About 53 (67%) children had multimorbidity, and 14 (17.7%) children died. All deaths were in children with comorbidities with tuberculosis and malignancy being associated with 43% of deaths. Nearly 5% of children reported long-COVID symptoms highlighting the need for prolonged follow-up in those children. Conclusion Despite lower admissions and severity, high mortality and morbidity was documented in our pediatric cohort. The presence of comorbidity and inadequate care organization likely contributed to high mortality. COVID-19 centers of low-income settings should emphasize optimizing the care of children with COVID-19 and multimorbidity, and vaccination should be considered in those children to prevent high morbidity and mortality.
{"title":"Clinical Characteristics and Outcome of Pediatric COVID-19 Patients in Ethiopia During the Early COVID-19 Pandemic: A Prospective Cohort Study","authors":"Abate Yeshidinber Weldetsadik, Mahlet Abayneh, Mebratu Abraha, Sisay Sirgu Betizazu, Betregiorgis Hailu Zegeye","doi":"10.2147/PHMT.S359333","DOIUrl":"https://doi.org/10.2147/PHMT.S359333","url":null,"abstract":"Introduction Most previous pediatric COVID-19 studies reported milder disease in children. However, there are limited pediatric data from low-income settings. We aimed to assess the characteristics and outcomes of pediatric COVID-19 in Ethiopia. Setting St. Paul’s COVID-19 treatment center; a tertiary COVID-19 center. Pediatric care was provided in a dedicated ward but with a common ICU. Methods St. Paul’s Hospital COVID-19 cohort (SPC-19) included inpatient COVID-19 RT-PCR confirmed cases from August 2020 to January 2021. Data were extracted from case report forms attached to patient charts and completed by the clinicians. Data were uploaded into the Redcap database and exported to SPSS 20 for analysis. Binary logistic regression and chi-square test were used in the analysis. Results Seventy-nine patients 0–19 years were included from the SPC-19 cohort over 6 months. Pediatric admissions accounted for 11% of cases in the cohort. The mean age (SD) was 6.9 (±6.36) years and 40 (50.6%) were female. The disease was asymptomatic or mild in 57 (72.2%), moderate in 15 (19%), and severe or critical in 7 (8.8%). The commonest presentations in symptomatic children were prostration (26.6%) followed by vomiting (12.7%), fever and cough (11.4% each), and dyspnea (10%). About 53 (67%) children had multimorbidity, and 14 (17.7%) children died. All deaths were in children with comorbidities with tuberculosis and malignancy being associated with 43% of deaths. Nearly 5% of children reported long-COVID symptoms highlighting the need for prolonged follow-up in those children. Conclusion Despite lower admissions and severity, high mortality and morbidity was documented in our pediatric cohort. The presence of comorbidity and inadequate care organization likely contributed to high mortality. COVID-19 centers of low-income settings should emphasize optimizing the care of children with COVID-19 and multimorbidity, and vaccination should be considered in those children to prevent high morbidity and mortality.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"165 - 174"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48784532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammedawel Abdishu, T. Gobena, M. Damena, Hassen Abdi, Abdi Birhanu
Background Understanding the determinants of malaria morbidity offers helpful insights toward the changing malaria situation, which might lead to the adjustment of malaria program activities. Even though the determinants of malaria morbidity remain unknown, school-aged children were the highest malaria morbidity contributors in the East Hararghe Zone. Therefore, this study aimed to assess the determinants of malaria morbidity among school-aged children in the study area from February 1 to May 31, 2020. Methods A case-control study was conducted among school-aged children living in ten randomly selected low, moderate, and high malaria transmission kebeles. Cases were confirmed as positive for malaria, while controls were confirmed as negative for malaria among randomly selected school-aged children. Rapid diagnostic testing (RDT) and blood film (BF) malaria testing methods were used. Multivariable logistic regression was used to identify association between malaria and its determinants. Results The determinants of malaria infection were having no formal education (adjusted odds ratio (AOR)=4.91, 95% CI: 1.20–20.17), low family wealth index (AOR=2.50, 95% CI: 1.22–5.12), being from rural residence (AOR=2.34, 95% CI: 1.87–4.12), living near to stagnant water (AOR=2.01, 95% CI: 1.14–3.54), having a maximum of three family members (AOR=0.37, 95% CI: 0.18–0.78), using indoor residual spraying (IRS) (AOR=0.15, 95% CI: 0.08–0.29) and long-lasting insecticide-treated net (LLITN) over the last night (AOR=0.19, 95% CI: 0.10–0.35), and living in the house surrounded by cultivated land(AOR=0.24, 95%CI: 0.10-0.60) compared with their counterparts. Conclusion This study revealed that residence, family size, education, wealth index, stagnant water existence, and using LLITN and IRS had significant association with malaria morbidity. Thus, all concerned bodies, including the community should strengthen working on stagnant water elimination around their house to cut the breeding site of the malaria vector mosquito. Moreover, the findings have an important implication for improving interventions targeting the economic status and literacy of the society that may help in the reduction of the risk of malaria in the school-aged children.
{"title":"Determinants of Malaria Morbidity Among School-Aged Children Living in East Hararghe Zone, Oromia, Ethiopia: A Community-Based Case–Control Study","authors":"Mohammedawel Abdishu, T. Gobena, M. Damena, Hassen Abdi, Abdi Birhanu","doi":"10.2147/PHMT.S347621","DOIUrl":"https://doi.org/10.2147/PHMT.S347621","url":null,"abstract":"Background Understanding the determinants of malaria morbidity offers helpful insights toward the changing malaria situation, which might lead to the adjustment of malaria program activities. Even though the determinants of malaria morbidity remain unknown, school-aged children were the highest malaria morbidity contributors in the East Hararghe Zone. Therefore, this study aimed to assess the determinants of malaria morbidity among school-aged children in the study area from February 1 to May 31, 2020. Methods A case-control study was conducted among school-aged children living in ten randomly selected low, moderate, and high malaria transmission kebeles. Cases were confirmed as positive for malaria, while controls were confirmed as negative for malaria among randomly selected school-aged children. Rapid diagnostic testing (RDT) and blood film (BF) malaria testing methods were used. Multivariable logistic regression was used to identify association between malaria and its determinants. Results The determinants of malaria infection were having no formal education (adjusted odds ratio (AOR)=4.91, 95% CI: 1.20–20.17), low family wealth index (AOR=2.50, 95% CI: 1.22–5.12), being from rural residence (AOR=2.34, 95% CI: 1.87–4.12), living near to stagnant water (AOR=2.01, 95% CI: 1.14–3.54), having a maximum of three family members (AOR=0.37, 95% CI: 0.18–0.78), using indoor residual spraying (IRS) (AOR=0.15, 95% CI: 0.08–0.29) and long-lasting insecticide-treated net (LLITN) over the last night (AOR=0.19, 95% CI: 0.10–0.35), and living in the house surrounded by cultivated land(AOR=0.24, 95%CI: 0.10-0.60) compared with their counterparts. Conclusion This study revealed that residence, family size, education, wealth index, stagnant water existence, and using LLITN and IRS had significant association with malaria morbidity. Thus, all concerned bodies, including the community should strengthen working on stagnant water elimination around their house to cut the breeding site of the malaria vector mosquito. Moreover, the findings have an important implication for improving interventions targeting the economic status and literacy of the society that may help in the reduction of the risk of malaria in the school-aged children.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"183 - 193"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46132296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Abebe, G. Seyoum, Bahru Emamu, Demissie Teshome
Introduction Congenital hydrocephalus is one of the commonest congenital anomalies of the central nervous system. It is characterized by extensive accumulation of cerebrospinal fluid within the ventricles of the brain due to an imbalance between synthesis and absorption of cerebrospinal fluid. This study was planned to investigate the incidence and associated risk factors of congenital hydrocephalus. Methods Unmatched case–control study was conducted in 34 (cases) and 104 (controls) pregnant women. Maternal data were collected from a structured questionnaire, and fetal-related data were recorded from obstetric ultrasound. Epi-info 7 and SPSS version 24 were used for data entry and analysis, respectively. The association between congenital hydrocephalus and risk factors was evaluated using binary logistic regression. Results The incidence of congenital hydrocephalus was 2.67 per 1000 pregnancies. The result of multivariate logistic regression indicated that alcohol use and iron with folic acid supplementation during pregnancy were significantly associated with the development of congenital hydrocephalus (OR: 7.64, 95% CI: 1.97–29.66 and p-value: 0.003 and OR: 0.186, 95% CI: 0.07–0.49 and p-value: 0.001, respectively). Maternal exposure to typhus and typhoid and use of antibiotics during early pregnancy were also significantly associated with congenital hydrocephalus. Moreover, significant association was also observed between the simultaneous development of spina bifida and congenital hydrocephalus (p-value 0.03). Conclusion In conclusion, alcohol consumption, unprescribed use of antibiotics and infection during pregnancy as well as absence of folic acid supplementation may predispose to congenital hydrocephalus.
{"title":"Congenital Hydrocephalus and Associated Risk Factors: An Institution-Based Case–Control Study, Dessie Town, North East Ethiopia","authors":"M. Abebe, G. Seyoum, Bahru Emamu, Demissie Teshome","doi":"10.2147/PHMT.S364447","DOIUrl":"https://doi.org/10.2147/PHMT.S364447","url":null,"abstract":"Introduction Congenital hydrocephalus is one of the commonest congenital anomalies of the central nervous system. It is characterized by extensive accumulation of cerebrospinal fluid within the ventricles of the brain due to an imbalance between synthesis and absorption of cerebrospinal fluid. This study was planned to investigate the incidence and associated risk factors of congenital hydrocephalus. Methods Unmatched case–control study was conducted in 34 (cases) and 104 (controls) pregnant women. Maternal data were collected from a structured questionnaire, and fetal-related data were recorded from obstetric ultrasound. Epi-info 7 and SPSS version 24 were used for data entry and analysis, respectively. The association between congenital hydrocephalus and risk factors was evaluated using binary logistic regression. Results The incidence of congenital hydrocephalus was 2.67 per 1000 pregnancies. The result of multivariate logistic regression indicated that alcohol use and iron with folic acid supplementation during pregnancy were significantly associated with the development of congenital hydrocephalus (OR: 7.64, 95% CI: 1.97–29.66 and p-value: 0.003 and OR: 0.186, 95% CI: 0.07–0.49 and p-value: 0.001, respectively). Maternal exposure to typhus and typhoid and use of antibiotics during early pregnancy were also significantly associated with congenital hydrocephalus. Moreover, significant association was also observed between the simultaneous development of spina bifida and congenital hydrocephalus (p-value 0.03). Conclusion In conclusion, alcohol consumption, unprescribed use of antibiotics and infection during pregnancy as well as absence of folic acid supplementation may predispose to congenital hydrocephalus.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"175 - 182"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49392286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Children with juvenile arthritis (JA) experience pain, stiffness, fatigue, and decreased motion leading to difficulties with daily activities and low physical activity (PA). PA is critical to improve health and function and mitigate JA-associated symptoms. This study evaluated the evidence for PA interventions in children with JA. Materials and Methods A systematic review of randomized controlled trials (RCTs) of PA interventions in children with JA was conducted. Ovid (Medline), Cochrane Library, EMBASE, and CINAHL databases were searched for papers published in English between 1/1/1946 and 9/1/2021. Studies which concurrently assessed medical interventions were excluded. Participant and intervention characteristics and outcomes were extracted. Study internal validity and intervention attributes were assessed. Results A total of 555 studies were identified, with 13 studies from 10 countries included. Data from 672 children diagnosed with juvenile idiopathic arthritis (JIA) (range of mean ages, 8.7 to 16.1 years) were analyzed. Fifty-two percent of intervention arms incorporated strengthening exercise alone or combined with other exercise, with 61.9% performed 3x/week. About 43.5% of sessions lasted >45 to ≤60 minutes and 65.2% of programs were ≥12 to <28 weeks. PA interventions improved function and symptoms without adverse events. Intervention details were missing especially regarding PA intensity, reasons for dropouts, and adherence. Only two studies incorporated strategies to promote adherence. Discussion RCTs of PA interventions in JA only include JIA. Available RCTs used mixed modes of interventions. Reporting of PA interventions lacks sufficient detail to discern the dose-response relationship. Strategies to motivate engagement in PA and to support families to promote PA are lacking, as are studies of long-term outcomes. Conclusion There are limited RCTs of PA interventions in JIA. Adherence was better with low intensity programs. PA interventions for JIA yield positive health benefits but better reporting of PA intervention details is needed to generate more high-quality evidence and inform clinical practice. Prospero Registration Maura Iversen, Johan von Heideken, Marie Andre. Physical Activity in Children with Rheumatic Diseases: a systematic review. PROSPERO 2021 CRD42021274634 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274634.
引言患有幼年关节炎（JA）的儿童会经历疼痛、僵硬、疲劳和运动减少，导致日常活动困难和体力活动不足（PA）。PA对改善健康和功能以及缓解JA相关症状至关重要。本研究评估了PA干预JA儿童的证据。材料与方法对JA患儿PA干预的随机对照试验（RCTs）进行系统回顾。检索Ovid（Medline）、Cochrane图书馆、EMBASE和CINAHL数据库中1946年1月1日至2021年9月1日期间以英语发表的论文。同时评估医疗干预措施的研究被排除在外。提取参与者和干预的特征和结果。评估了研究的内部有效性和干预属性。结果共确定555项研究，其中包括来自10个国家的13项研究。分析了672名被诊断为青少年特发性关节炎（JIA）的儿童（平均年龄范围为8.7至16.1岁）的数据。52%的干预组将强化运动单独或与其他运动相结合，61.9%的干预组每周进行3次。约43.5%的疗程持续时间>45至≤60分钟，65.2%的疗程≥12至<28周。PA干预改善了功能和症状，没有出现不良事件。干预细节缺失，尤其是在PA强度、辍学原因和依从性方面。只有两项研究纳入了促进依从性的策略。讨论PA干预JA的随机对照试验仅包括JIA。现有的随机对照试验采用了混合干预模式。PA干预措施的报告缺乏足够的细节来辨别剂量-反应关系。缺乏激励参与PA和支持家庭促进PA的策略，也缺乏对长期结果的研究。结论JIA患者PA干预的随机对照试验有限。低强度项目的依从性更好。对JIA的PA干预产生了积极的健康益处，但需要更好地报告PA干预细节，以产生更多高质量的证据并为临床实践提供信息。Prospero Registration Maura Iversen，Johan von Heidken，Marie Andre。类风湿性疾病儿童的体育活动：一项系统综述。PROSPERO 2021 CRD42021274634可从以下网站获得：https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274634.
{"title":"Physical Activity Interventions in Children with Juvenile Idiopathic Arthritis: A Systematic Review of Randomized Controlled Trials","authors":"M. Iversen, M. André, J. von Heideken","doi":"10.2147/PHMT.S282611","DOIUrl":"https://doi.org/10.2147/PHMT.S282611","url":null,"abstract":"Introduction Children with juvenile arthritis (JA) experience pain, stiffness, fatigue, and decreased motion leading to difficulties with daily activities and low physical activity (PA). PA is critical to improve health and function and mitigate JA-associated symptoms. This study evaluated the evidence for PA interventions in children with JA. Materials and Methods A systematic review of randomized controlled trials (RCTs) of PA interventions in children with JA was conducted. Ovid (Medline), Cochrane Library, EMBASE, and CINAHL databases were searched for papers published in English between 1/1/1946 and 9/1/2021. Studies which concurrently assessed medical interventions were excluded. Participant and intervention characteristics and outcomes were extracted. Study internal validity and intervention attributes were assessed. Results A total of 555 studies were identified, with 13 studies from 10 countries included. Data from 672 children diagnosed with juvenile idiopathic arthritis (JIA) (range of mean ages, 8.7 to 16.1 years) were analyzed. Fifty-two percent of intervention arms incorporated strengthening exercise alone or combined with other exercise, with 61.9% performed 3x/week. About 43.5% of sessions lasted >45 to ≤60 minutes and 65.2% of programs were ≥12 to <28 weeks. PA interventions improved function and symptoms without adverse events. Intervention details were missing especially regarding PA intensity, reasons for dropouts, and adherence. Only two studies incorporated strategies to promote adherence. Discussion RCTs of PA interventions in JA only include JIA. Available RCTs used mixed modes of interventions. Reporting of PA interventions lacks sufficient detail to discern the dose-response relationship. Strategies to motivate engagement in PA and to support families to promote PA are lacking, as are studies of long-term outcomes. Conclusion There are limited RCTs of PA interventions in JIA. Adherence was better with low intensity programs. PA interventions for JIA yield positive health benefits but better reporting of PA intervention details is needed to generate more high-quality evidence and inform clinical practice. Prospero Registration Maura Iversen, Johan von Heideken, Marie Andre. Physical Activity in Children with Rheumatic Diseases: a systematic review. PROSPERO 2021 CRD42021274634 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274634.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"115 - 143"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43492752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Severe acute malnutrition is the most prevalent reason for admission to a pediatric unit, and it is a leading cause of mortality in many countries, including Ethiopia, at 25% to 30%, where it affects both developed and developing countries. The objective of this study was to assess treatment outcomes and associated factors among children aged 6–59 months with severe acute malnutrition. Methods A cross-sectional study was conducted using secondary data from medical records of patients enrolled in the therapeutic feeding center from January 2016 to March 2019. There were 385 samples collected at 3 public referral hospitals in Addis Ababa, which were selected by simple random sampling. A structured questionnaire was used to collect data from the available individual folders and registers. The data analysis was performed using binary and multivariable logistic regression models. The odds ratio with 95% CI was used to identify predictor variables. Variables that have a p-value <0.05 were considered significant. Results Children who had tuberculosis were 79% less likely to recover than those who had no tuberculosis. In this study, deaths accounted for 9.1%, recovered were 72.2%, and defaulters accounted for 11.6% with a mean length of stay of 18.6 (CI: 16.9, 20.2) days and an average weight gain of 7.2 g/kg/day (CI: 5.7, 8.2). Conclusion Treating comorbidities on time can help children to recover early and reduce readmission. Integration of severe acute malnutrition screening into all service delivery points can help early identification and treatment. In the meantime, treating them with ready-to-use therapeutic feeding has a significant change in recovery.
{"title":"Treatment Outcome and Associated Factors of Acute Malnutrition Among Children in the Therapeutic Feeding Center of Public Hospitals in Addis Ababa, Ethiopia: An Institutional-Based Cross-Sectional Study","authors":"Melat Mezemir, Meskerem Girma, D. Bekele","doi":"10.2147/PHMT.S296979","DOIUrl":"https://doi.org/10.2147/PHMT.S296979","url":null,"abstract":"Background Severe acute malnutrition is the most prevalent reason for admission to a pediatric unit, and it is a leading cause of mortality in many countries, including Ethiopia, at 25% to 30%, where it affects both developed and developing countries. The objective of this study was to assess treatment outcomes and associated factors among children aged 6–59 months with severe acute malnutrition. Methods A cross-sectional study was conducted using secondary data from medical records of patients enrolled in the therapeutic feeding center from January 2016 to March 2019. There were 385 samples collected at 3 public referral hospitals in Addis Ababa, which were selected by simple random sampling. A structured questionnaire was used to collect data from the available individual folders and registers. The data analysis was performed using binary and multivariable logistic regression models. The odds ratio with 95% CI was used to identify predictor variables. Variables that have a p-value <0.05 were considered significant. Results Children who had tuberculosis were 79% less likely to recover than those who had no tuberculosis. In this study, deaths accounted for 9.1%, recovered were 72.2%, and defaulters accounted for 11.6% with a mean length of stay of 18.6 (CI: 16.9, 20.2) days and an average weight gain of 7.2 g/kg/day (CI: 5.7, 8.2). Conclusion Treating comorbidities on time can help children to recover early and reduce readmission. Integration of severe acute malnutrition screening into all service delivery points can help early identification and treatment. In the meantime, treating them with ready-to-use therapeutic feeding has a significant change in recovery.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"145 - 154"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49252936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fikadu Ejeta, Diriba Feyisa, Temesgen Aferu, Jafer Siraj, Demeke Melkam, Ahmed Ali
Introduction Obstacles encountered when maintaining excellent dispensing practices for children include a lack of age-appropriate dosage forms, a shortage of medications in appropriate strengths for children, a lack of appetizing drugs, and a lack of competence in pediatric pharmacy. These difficulties contribute to ineffective dispensing procedures and an urgent need to study whether oral dose forms of medications are dispensed to children in a rational way. Objective The purpose of this study is to evaluate the rational dispensing of oral dosage forms of medicines to children, as well as the factors that influence this practice. Methods Using validated indicators, a cross-sectional study design was utilized to analyze the rational dispensing practice of oral dosage forms of medicines administered to children under the age of 12 years in seven pharmacies and two drug stores over a one-month period. Results and discussions Out of 810 medicines, 11.7% and 4% were irrationally manipulated, 5.8% and 1.8% needed manipulation, 3.7% and 0.2% were alternatively dispensed, 8.8% and 7.5% of the medicines had correct advice on their label and also 745 medicines were adequately labeled in the hospital and the selected drug stores. In this study, 92% of medicines were adequately labeled and had sufficient advice on their labels, 15.3% of medicines were irrationally manipulated and around 7.7% of the dosage forms needed manipulation during dispensing. The type of medicine retail outlet had a significant effect on the percentage of instances where alternative solid oral dosage forms were dispensed (p = 0.003), the percentage of dosage forms were adequately labeled (p = 0.008), and the percentage of dosage forms were irrationally manipulated before dispensing (p = 0.001). Conclusion The rational dispensing practice of oral dosage forms of medicines was relatively poor and there is room for improvement.
{"title":"Rational Dispensing of Oral Dosage Forms of Medicines to Children and Its Associated Factors in South West Ethiopia","authors":"Fikadu Ejeta, Diriba Feyisa, Temesgen Aferu, Jafer Siraj, Demeke Melkam, Ahmed Ali","doi":"10.2147/PHMT.S360383","DOIUrl":"https://doi.org/10.2147/PHMT.S360383","url":null,"abstract":"Introduction Obstacles encountered when maintaining excellent dispensing practices for children include a lack of age-appropriate dosage forms, a shortage of medications in appropriate strengths for children, a lack of appetizing drugs, and a lack of competence in pediatric pharmacy. These difficulties contribute to ineffective dispensing procedures and an urgent need to study whether oral dose forms of medications are dispensed to children in a rational way. Objective The purpose of this study is to evaluate the rational dispensing of oral dosage forms of medicines to children, as well as the factors that influence this practice. Methods Using validated indicators, a cross-sectional study design was utilized to analyze the rational dispensing practice of oral dosage forms of medicines administered to children under the age of 12 years in seven pharmacies and two drug stores over a one-month period. Results and discussions Out of 810 medicines, 11.7% and 4% were irrationally manipulated, 5.8% and 1.8% needed manipulation, 3.7% and 0.2% were alternatively dispensed, 8.8% and 7.5% of the medicines had correct advice on their label and also 745 medicines were adequately labeled in the hospital and the selected drug stores. In this study, 92% of medicines were adequately labeled and had sufficient advice on their labels, 15.3% of medicines were irrationally manipulated and around 7.7% of the dosage forms needed manipulation during dispensing. The type of medicine retail outlet had a significant effect on the percentage of instances where alternative solid oral dosage forms were dispensed (p = 0.003), the percentage of dosage forms were adequately labeled (p = 0.008), and the percentage of dosage forms were irrationally manipulated before dispensing (p = 0.001). Conclusion The rational dispensing practice of oral dosage forms of medicines was relatively poor and there is room for improvement.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"103 - 113"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44507186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Necrotizing Enter colitis (NEC) is the most common multifactorial and devastating gastrointestinal emergency which primarily affects premature infants. The purpose of this study was to identify the prevalence of Necrotizing Enterocolitis and its associated factors among preterm neonates admitted to Neonatal Intensive Care Units in Gurage Zone hospitals. Methods Institution-based cross-sectional study design was employed. The simple Random Sampling Technique was applied to collect the data using a structured questionnaire. Data were cleaned, checked for inconsistencies, coded and entered via EPI data 3.1, and exported to Stata version 14 for further analysis. The data were processed by Stata 14 to estimate the prevalence of necrotizing enterocolitis. Results The prevalence of Necrotizing Enterocolitis among neonates was 28 (9.7%) 95% CI of 6. 8–13.7%. Birth weight (AOR: 7.33 95% CI (2.04: 26.38)), presence of maternal infection (AOR: 6.09, 95% CI (1.31:28.26)), length of hospital stay (AOR: 3.28, 95% CI (1.20, 8.96)), and initiating trophic feeding (AOR: 5.89, 95% CI (2.27: 15.33)) were associated with neonatal necrotizing enterocolitis. Conclusion The prevalence of Necrotizing Enterocolitis among preterm neonates was significant and special attention is needed for premature neonates with low birth weight and born from mothers with infection during pregnancy. Minimizing the length of hospital stay will be very useful to prevent the occurrence of Necrotizing Enterocolitis.
{"title":"Necrotizing Enterocolitis and Its Predictors Among Preterm Neonates Admitted in Neonatal Intensive Care Units of Gurage Zone Public Hospitals, Southwest Ethiopia, 2021","authors":"Bogale Chekole Temere, Agerie Aynalem Mewahegn, Bitew Tefera Zewudie, Fisha Alebel GebreEyesus, Amare Kassaw, Belete Gelaw Walle, Shegaw Geze Tenaw, Yibeltal Mesfin, Muche Argaw, Haymanot Abebe, Shegaw Tesfa, Netsanet Habte, Robel Birhanu, Wesila Seid","doi":"10.2147/PHMT.S353663","DOIUrl":"https://doi.org/10.2147/PHMT.S353663","url":null,"abstract":"Background Necrotizing Enter colitis (NEC) is the most common multifactorial and devastating gastrointestinal emergency which primarily affects premature infants. The purpose of this study was to identify the prevalence of Necrotizing Enterocolitis and its associated factors among preterm neonates admitted to Neonatal Intensive Care Units in Gurage Zone hospitals. Methods Institution-based cross-sectional study design was employed. The simple Random Sampling Technique was applied to collect the data using a structured questionnaire. Data were cleaned, checked for inconsistencies, coded and entered via EPI data 3.1, and exported to Stata version 14 for further analysis. The data were processed by Stata 14 to estimate the prevalence of necrotizing enterocolitis. Results The prevalence of Necrotizing Enterocolitis among neonates was 28 (9.7%) 95% CI of 6. 8–13.7%. Birth weight (AOR: 7.33 95% CI (2.04: 26.38)), presence of maternal infection (AOR: 6.09, 95% CI (1.31:28.26)), length of hospital stay (AOR: 3.28, 95% CI (1.20, 8.96)), and initiating trophic feeding (AOR: 5.89, 95% CI (2.27: 15.33)) were associated with neonatal necrotizing enterocolitis. Conclusion The prevalence of Necrotizing Enterocolitis among preterm neonates was significant and special attention is needed for premature neonates with low birth weight and born from mothers with infection during pregnancy. Minimizing the length of hospital stay will be very useful to prevent the occurrence of Necrotizing Enterocolitis.","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"13 1","pages":"95 - 102"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42054807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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