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VI, 1. Epidemiology of toroviruses. VI、 1。圆环病毒的流行病学。
Perspectives in medical virology
Pub Date : 2003-01-01 Epub Date: 2004-09-14 DOI: 10.1016/S0168-7069(03)09038-4
Martin Petric

The discovery of the toroviruses, which comprise a genus of the family Coronaviridae, began with the serendipitous isolation of the morphologically unique Berne virus (ETV) in feces of a horse. This chapter discusses the epidemiology of toroviruses. ETV was first detected by the isolation of the virus in cell culture. Growth of ETV in cell culture allowed for the characterization of the virus, in terms of its morphology, morphogenesis, protein and nucleic acid composition, and facilitated investigations into its replication strategy. The successful propagation of ETV in cell cultures facilitated the development of a virus-neutralization assay that made it possible to gain an insight into the sero-epidemiology of this virus in various animal populations. Although ETV has been isolated, only once from a horse, there is evidence that antigenically related viruses are widespread in the equine population. The sero-prevalence of ETV-specific antibody as measured by virus neutralization test is very high in the horse population with 35% of randomly collected sera in Germany and 81% in Switzerland being positive.

托罗病毒是冠状病毒科的一个属，它的发现始于偶然从一匹马的粪便中分离出形态独特的伯尔尼病毒(ETV)。本章讨论torovirus的流行病学。在细胞培养中分离病毒，首次检测到ETV。ETV在细胞培养物中的生长可以从形态、形态发生、蛋白质和核酸组成等方面对病毒进行表征，并有助于研究其复制策略。ETV在细胞培养物中的成功繁殖促进了病毒中和试验的发展，从而有可能深入了解该病毒在各种动物群体中的血清流行病学。虽然已经从一匹马身上分离出了ETV，但有证据表明，抗原性相关的病毒在马群中广泛存在。通过病毒中和试验测定的etv特异性抗体的血清流行率在马群中非常高，在德国随机收集的血清中有35%呈阳性，在瑞士有81%呈阳性。
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引用次数: 1
II, 5. Translation of rotavirus mRNAs in the infected cell 二世,5。轮状病毒mrna在感染细胞中的翻译
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)09012-8
D. Poncet
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引用次数: 11
II, 14. Rotavirus-like particle vaccines evaluated in a pig model of human rotavirus diarrhea and in cattle 二世,14。轮状病毒样颗粒疫苗在人轮状病毒腹泻猪模型和牛模型中的评价
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)09021-9
Lijuan Yuan, L. Saif
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引用次数: 1
II, 15. DNA-based rotavirus vaccines 二世,15。基于dna的轮状病毒疫苗
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)09022-0
J. Herrmann
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引用次数: 0
III, 1. Aspects of the molecular biology of enteric adenoviruses 三世,1。肠腺病毒分子生物学的几个方面
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)09024-4
Fiona A. Stevenson, V. Mautner
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引用次数: 5
Hepatitis B virus mutants: emergence and impact on diagnostic detection 乙型肝炎病毒突变体:出现及其对诊断检测的影响
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)10003-1
P. Coleman
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引用次数: 2
Subject index. 主题索引。
Perspectives in medical virology
Pub Date : 2003-01-01 Epub Date: 2004-09-14 DOI: 10.1016/S0168-7069(03)09043-8
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引用次数: 0
IV, 5. Molecular epidemiology of human caliciviruses 第四,5。人类杯状病毒的分子流行病学
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)09031-1
M. Koopmans, E. V. Strien, H. Vennema
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引用次数: 23
VI, 4. Histopathology of viral gastrointestinal infections in the immunocompromised 第六,4。免疫功能低下者病毒性胃肠道感染的组织病理学研究
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)09041-4
J. Grant
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引用次数: 0
Torque Teno Virus (TTV): molecular virology and clinical implications 转矩病毒(TTV):分子病毒学和临床意义
Perspectives in medical virology
Pub Date : 2003-01-01 DOI: 10.1016/S0168-7069(03)10009-2
H. Okamoto, T. Nishizawa, Masaharu Takahashi
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引用次数: 20
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