A. Vaandering, S. Roels, B. Yalvaç, N. Reulens, B. Reniers, F. Vanhoutte, V. Remouchamps, Y. Lievens, R. Weytjens
{"title":"Favouring quality improvement initiatives: the experience of the Belgian College of Radiation Oncology","authors":"A. Vaandering, S. Roels, B. Yalvaç, N. Reulens, B. Reniers, F. Vanhoutte, V. Remouchamps, Y. Lievens, R. Weytjens","doi":"10.21037/pcm-22-15","DOIUrl":"https://doi.org/10.21037/pcm-22-15","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47946789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Russano, G. Perrone, G. D. Di Fazio, A. Galletti, F. Citarella, V. Santo, L. Brunetti, Alessia Vendittelli, B. Vincenzi, G. Tonini, D. Santini
{"title":"Uncommon EGFR mutations in non-small-cell lung cancer","authors":"M. Russano, G. Perrone, G. D. Di Fazio, A. Galletti, F. Citarella, V. Santo, L. Brunetti, Alessia Vendittelli, B. Vincenzi, G. Tonini, D. Santini","doi":"10.21037/pcm-22-14","DOIUrl":"https://doi.org/10.21037/pcm-22-14","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48826754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merkel cell carcinoma (MCC), melanoma, and keratinocyte carcinomas (KC), basal cell carcinoma (BCC) and squamous cell carcinoma, are among the most common and/or aggressive malignancies of the skin. Traditional staging parameters remain the most important and widely utilized prognostic and predictive tools. However, given the recent explosion in the literature on immunohistochemical and molecular-genetic markers for these skin tumors, novel predictive and prognostic biomarkers are emerging. Herein, we sought to summarize well-established and emerging predictive and prognostic biomarkers in these cutaneous malignancies. We present the following article in accordance with the Narrative Review Reporting Checklist (available at: http:// dx.doi.org/10.21037/pcm-21-6).
{"title":"A narrative review of predictive and prognostic biomarkers in skin tumors","authors":"A. Stagner, R. Nazarian","doi":"10.21037/PCM-21-6","DOIUrl":"https://doi.org/10.21037/PCM-21-6","url":null,"abstract":"Merkel cell carcinoma (MCC), melanoma, and keratinocyte carcinomas (KC), basal cell carcinoma (BCC) and squamous cell carcinoma, are among the most common and/or aggressive malignancies of the skin. Traditional staging parameters remain the most important and widely utilized prognostic and predictive tools. However, given the recent explosion in the literature on immunohistochemical and molecular-genetic markers for these skin tumors, novel predictive and prognostic biomarkers are emerging. Herein, we sought to summarize well-established and emerging predictive and prognostic biomarkers in these cutaneous malignancies. We present the following article in accordance with the Narrative Review Reporting Checklist (available at: http:// dx.doi.org/10.21037/pcm-21-6).","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49232946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Shafi, Ashley Patton, A. Rogers, V. Grignol, S. Oghumu, O. Iwenofu
{"title":"Sporadic mesenteric desmoid-type fibromatosis with “double-hit” T41A and S45P beta-catenin mutation profile: a case report of an extremely rare event—clinically relevant or much ado about nothing?","authors":"S. Shafi, Ashley Patton, A. Rogers, V. Grignol, S. Oghumu, O. Iwenofu","doi":"10.21037/pcm-22-2","DOIUrl":"https://doi.org/10.21037/pcm-22-2","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41974915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-84087-7_10
Bharat Jasani, R. Huss, C. Taylor
{"title":"Analytical Phase: Current Controls; Fit for Purpose Selection and Validation","authors":"Bharat Jasani, R. Huss, C. Taylor","doi":"10.1007/978-3-030-84087-7_10","DOIUrl":"https://doi.org/10.1007/978-3-030-84087-7_10","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":"9 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50981054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-84087-7_15
B. Jasani, R. Huss, C. Taylor
{"title":"Implementation of Precision Cancer Diagnostic Test","authors":"B. Jasani, R. Huss, C. Taylor","doi":"10.1007/978-3-030-84087-7_15","DOIUrl":"https://doi.org/10.1007/978-3-030-84087-7_15","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":"8 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50981351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of digital and integrative pathology for the detection of translocations: a narrative review","authors":"C. Beretta, S. Ceola, F. Pagni, V. L’Imperio","doi":"10.21037/pcm-21-56","DOIUrl":"https://doi.org/10.21037/pcm-21-56","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48656826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
National University Cancer Institute, Singapore, Singapore; Novi High School, Novi, MI, USA Contributions: (I) Conception and design: TY Chan, B Vellayappan; (II) Administrative support: All authors; (III) Provision of study materials or patients: TY Chan, B Vellayappan; (IV) Collection and assembly of data: TY Chan, B Vellayappan; (V) Data analysis and interpretation: TY Chan, B Vellayappan; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Balamurugan Vellayappan. 1E Kent Ridge Road, Level 7 Tower Block, Singapore 119228, Singapore. Email: bala_vellayappan@nuhs.edu.sg.
新加坡国立大学癌症研究所，新加坡;(1)概念与设计:TY Chan, B Vellayappan;行政支助:所有作者;(III)提供研究资料或患者:TY Chan, B Vellayappan;(四)资料收集及汇编:TY Chan, B Vellayappan;(V)数据分析和解释:TY Chan, B Vellayappan;(六)稿件撰写:全体作者;(七)稿件最终审定:全体作者。寄信人:Balamurugan Vellayappan，新加坡肯特岭路1E, 7楼，新加坡119228。电子邮件:bala_vellayappan@nuhs.edu.sg。
{"title":"Wielding a double-edged sword in head and neck cancers—diagnosis, risk factors and mitigation strategies of radiation-induced head and neck sarcomas: a narrative review","authors":"T. Chan, Venkatesh Alagappan, B. Vellayappan","doi":"10.21037/pcm-21-30","DOIUrl":"https://doi.org/10.21037/pcm-21-30","url":null,"abstract":"National University Cancer Institute, Singapore, Singapore; Novi High School, Novi, MI, USA Contributions: (I) Conception and design: TY Chan, B Vellayappan; (II) Administrative support: All authors; (III) Provision of study materials or patients: TY Chan, B Vellayappan; (IV) Collection and assembly of data: TY Chan, B Vellayappan; (V) Data analysis and interpretation: TY Chan, B Vellayappan; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Balamurugan Vellayappan. 1E Kent Ridge Road, Level 7 Tower Block, Singapore 119228, Singapore. Email: bala_vellayappan@nuhs.edu.sg.","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47713245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Oi, K. Yoh, S. Matsumoto, H. Izumi, Y. Shibata, T. Sakai, K. Nosaki, Y. Zenke, K. Goto
{"title":"KRAS G12V mutation as an acquired resistance mechanism after treatment with dabrafenib and trametinib in non-small cell lung cancer harbouring the BRAF V600E mutation: a case report","authors":"H. Oi, K. Yoh, S. Matsumoto, H. Izumi, Y. Shibata, T. Sakai, K. Nosaki, Y. Zenke, K. Goto","doi":"10.21037/pcm-21-55","DOIUrl":"https://doi.org/10.21037/pcm-21-55","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43750034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lung cancer in women","authors":"E. Baldini","doi":"10.21037/pcm-22-32","DOIUrl":"https://doi.org/10.21037/pcm-22-32","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44171323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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