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Life, death, and statins: association of statin prescriptions and survival in older general practice patients. 生命、死亡与他汀类药物:他汀类药物处方与老年全科病人生存的关系。
Pub Date : 2024-05-16 DOI: 10.1017/S1463423624000161
Adam J Hodgkins, Judy Mullan, Darren J Mayne, Andrew Bonney

Aims: This study serves as an exemplar to demonstrate the scalability of a research approach using survival analysis applied to general practice electronic health record data from multiple sites. Collection of these data, the subsequent analysis, and the preparation of practice-specific reports were performed using a bespoke distributed data collection and analysis software tool.

Background: Statins are a very commonly prescribed medication, yet there is a paucity of evidence for their benefits in older patients. We examine the relationship between statin prescriptions for general practice patients over 75 and all-cause mortality.

Methods: We carried out a retrospective cohort study using survival analysis applied to data extracted from the electronic health records of five Australian general practices.

Findings: The data from 8025 patients were analysed. The median duration of follow-up was 6.48 years. Overall, 52 015 patient-years of data were examined, and the outcome of death from any cause was measured in 1657 patients (21%), with the remainder being censored. Adjusted all-cause mortality was similar for participants not prescribed statins versus those who were (HR 1.05, 95% CI 0.92-1.20, P = 0.46), except for patients with diabetes for whom all-cause mortality was increased (HR = 1.29, 95% CI: 1.00-1.68, P = 0.05). In contrast, adjusted all-cause mortality was significantly lower for patients deprescribed statins compared to those who were prescribed statins (HR 0.81, 95% CI 0.70-0.93, P < 0.001), including among females (HR = 0.75, 95% CI: 0.61-0.91, P < 0.001) and participants treated for secondary prevention (HR = 0.72, 95% CI: 0.60-0.86, P < 0.001). This study demonstrated the scalability of a research approach using survival analysis applied to general practice electronic health record data from multiple sites. We found no evidence of increased mortality due to statin-deprescribing decisions in primary care.

目的:本研究作为一个范例,展示了将生存分析应用于来自多个地点的全科电子健康记录数据的研究方法的可扩展性。背景:他汀类药物是一种非常常用的处方药,但在临床上的应用却非常有限:背景:他汀类药物是一种非常常见的处方药,但有关其对老年患者益处的证据却很少。我们研究了 75 岁以上全科患者的他汀类药物处方与全因死亡率之间的关系:我们采用生存分析法对从澳大利亚五家全科诊所电子健康记录中提取的数据进行了一项回顾性队列研究:分析了 8025 名患者的数据。随访时间的中位数为 6.48 年。总计检查了 52 015 个患者年的数据,对 1657 名患者(21%)的任何原因死亡结果进行了测量,其余患者均被剔除。未服用他汀类药物的患者与服用他汀类药物的患者的调整后全因死亡率相似(HR 1.05,95% CI 0.92-1.20,P = 0.46),但糖尿病患者的全因死亡率有所增加(HR = 1.29,95% CI:1.00-1.68,P = 0.05)。相反,与处方他汀类药物的患者相比,停用他汀类药物的患者调整后的全因死亡率明显降低(HR 0.81,95% CI 0.70-0.93,P < 0.001),包括女性(HR = 0.75,95% CI:0.61-0.91,P < 0.001)和接受二级预防治疗的参与者(HR = 0.72,95% CI:0.60-0.86,P < 0.001)。这项研究证明了一种研究方法的可扩展性,该方法将生存分析应用于来自多个地点的全科电子健康记录数据。我们没有发现任何证据表明,在初级医疗机构开具他汀类药物处方会导致死亡率上升。
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引用次数: 0
Could self-reported physical performance help predict individuals at the highest risk of mortality and hospital admission events in clinical practice? Findings from the Hertfordshire Cohort Study. 自我报告的体能表现是否有助于预测临床实践中死亡率和入院风险最高的人群?赫特福德郡队列研究的结果。
Pub Date : 2024-05-14 DOI: 10.1017/S1463423624000173
Roshan Rambukwella, Leo D Westbury, Camille Pearse, Kate A Ward, Cyrus Cooper, Elaine M Dennison

Aim: To consider how self-reported physical function measures relate to adverse clinical outcomes measured over 20 years of follow-up in a community-dwelling cohort (aged 59-73 at baseline) as compared with hand grip strength, a well-validated predictor of adverse events.

Background: Recent evidence has emphasized the significant association of physical activity, physical performance, and muscle strength with hospital admissions in older people. However, physical performance tests require staff availability, training, specialized equipment, and space to perform them, often not feasible or realistic in the context of a busy clinical setting.

Methods: In total, 2997 men and women were analyzed. Baseline predictors were measured grip strength (Jamar dynamometer) and the following self-reported measures: physical activity (Dallosso questionnaire); physical function score (SF-36 Health Survey); and walking speed. Participants were followed up from baseline (1998-2004) until December 2018 using UK Hospital Episode Statistics and mortality data, which report clinical outcomes using ICD-10 coding. Predictors in relation to the risk of mortality and hospital admission events were examined using Cox regression with and without adjustment for sociodemographic and lifestyle characteristics.

Findings: The mean age at baseline was 65.7 and 66.6 years among men and women, respectively. Over follow-up, 36% of men and 26% of women died, while 93% of men and 92% of women were admitted to hospital at least once. Physical activity, grip strength, SF-36 physical function, and walking speed were all strongly associated with adverse health outcomes in both sex- and fully adjusted analyses; poorer values for each of the predictors were related to greater risk of mortality (all-cause, cardiovascular-related) and any, neurological, cardiovascular, respiratory, any fracture, and falls admissions. SF-36 physical function and grip strength were similarly associated with the adverse health outcomes considered.

目的:在对社区居住人群(基线年龄为 59-73 岁)进行的 20 年随访中,考虑自我报告的身体功能测量结果与不良临床结果之间的关系,并与不良事件的有效预测指标--手部握力进行比较:背景:最近的证据强调,老年人的体力活动、体能表现和肌肉力量与入院治疗有很大关系。然而,体能测试需要人员、培训、专业设备和空间,在繁忙的临床环境中往往不可行或不现实:方法:共对 2997 名男性和女性进行了分析。基线预测指标是测量握力(Jamar测力计)和以下自我报告指标:体力活动(Dallosso问卷)、身体功能评分(SF-36健康调查)和步行速度。利用英国医院病例统计和死亡率数据对参与者进行了从基线(1998-2004年)到2018年12月的随访,这些数据使用ICD-10编码报告临床结果。在对社会人口学特征和生活方式特征进行调整或未进行调整的情况下,使用 Cox 回归对与死亡风险和入院事件相关的预测因素进行了研究:男性和女性的基线平均年龄分别为 65.7 岁和 66.6 岁。在随访期间,36%的男性和26%的女性死亡,93%的男性和92%的女性至少入院一次。在性别分析和完全调整分析中,体力活动、握力、SF-36 身体功能和步行速度都与不良健康后果密切相关;每个预测因子的值越差,死亡率(全因、心血管相关)和任何神经、心血管、呼吸系统、任何骨折和跌倒入院的风险就越高。SF-36 身体功能和握力同样与不良健康后果相关。
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引用次数: 0
Conceptualizing National Advisory Boards in primary care research: application to the Two in One HIV and COVID screening and testing model. 国家咨询委员会在初级保健研究中的概念化:应用于 "二合一 "HIV 和 COVID 筛查和检测模式。
Pub Date : 2024-05-09 DOI: 10.1017/S1463423624000100
Maranda C Ward, Paloma Delgado Setien, Abigail Konopasky, Donaldson F Conserve

The authors report on their development of a National Advisory Board (NAB) to guide a funded project: Two in One: HIV + COVID-19 Screening and Testing Model. This project aimed to improve primary care practitioners' capacity to routinize HIV, PrEP/PEP, and COVID-19 vaccine screenings for all their patients while relying on culturally responsive communication with their minoritized patients. To approach their monumental research and education tasks, they created a NAB, drawing from the literature on advisory boards to (a) promote board member engagement and (b) progress successfully through the six stages suggested for successful advisory boards. A midpoint survey and final focus groups with NAB members indicated mixed levels of engagement, a sense of time and work being valued, and pride in the media and academic reach of the project. The authors offer considerations for others considering forming a NAB to guide primary care research and interventions.

作者报告了他们建立国家咨询委员会(NAB)以指导一个受资助项目的情况:二合一:HIV + COVID-19 筛选和检测模式。该项目旨在提高初级保健从业人员的能力,使其能够对所有患者进行常规的 HIV、PrEP/PEP 和 COVID-19 疫苗筛查,同时依靠与少数族裔患者进行文化沟通。为了完成这项艰巨的研究和教育任务,他们借鉴有关咨询委员会的文献,创建了一个国家咨询委员会,以便:(a)促进委员会成员的参与;(b)在成功的咨询委员会所建议的六个阶段中取得成功。对国家咨询委员会成员进行的中期调查和最后的焦点小组讨论表明,他们的参与程度参差不齐,感觉时间和工作都得到了重视,并对项目的媒体和学术影响力感到自豪。作者为其他考虑成立国家咨询委员会以指导初级保健研究和干预措施的人提供了参考意见。
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引用次数: 0
Mother, child and adolescent health outcomes in two long-term refugee camp settings at the Thai-Myanmar border 2000-2018: a retrospective analysis. 2000-2018年泰缅边境两个长期难民营的母亲、儿童和青少年健康状况:回顾性分析。
Pub Date : 2024-05-09 DOI: 10.1017/S146342362400015X
Marie T Benner, Oliver Mohr, Wiphan Kaloy, Ammarat Sansoenboon, Aree Moungsookjarean, Peter Kaiser, Verena I Carrara, Rose McGready

Aim: The study assessed mothers, children and adolescents' health (MCAH) outcomes in the context of a Primary Health Care (PHC) project and associated costs in two protracted long-term refugee camps, along the Thai-Myanmar border.

Background: Myanmar refugees settled in Thailand nearly 40 years ago, in a string of camps along the border, where they fully depend on external support for health and social services. Between 2000 and 2018, a single international NGO has been implementing an integrated PHC project.

Methods: This retrospective study looked at the trends of MCAH indicators of mortality and morbidity and compared them to the sustainable development goals (SDGs) indicators. A review of programme documents explored and triangulated the evolution and changing context of the PHC services, and associated project costs were analysed. To verify changes over time, interviews with 12 key informants were conducted.

Findings: While maternal mortality (SDG3.1) remained high at 126.5/100,000 live births, child mortality (SDG 3.2) and infectious diseases in children under 5 (SDG 3.3) fell by 69% and by up to 92%, respectively. Maternal anaemia decreased by 30%; and more than 90% of pregnant women attended four or more antenatal care visits, whereas 80% delivered by a skilled birth attendant; caesarean section rates rose but remained low at an average of 3.7%; the adolescent (15-19 years) birth rate peaked at 188 per 1000 in 2015 but declined to 89/1000 in 2018 (SDG 3.7).

Conclusion: Comprehensive PHC delivery, with improved health provider competence in MCAH care, together with secured funding is an appropriate strategy to bring MCAH indicators to acceptable levels. However, inequities due to confinement in camps, fragmentation of specific health services, prevent fulfilment of the 2030 SDG Agenda to 'Leave no one behind'. Costs per birth was 115 EURO in 2018; however, MCAH expenditure requires further exploration over a longer period.

目的:本研究评估了泰缅边境两个长期难民营的初级卫生保健(PHC)项目的母亲、儿童和青少年健康(MCAH)成果以及相关成本:背景:近 40 年前,缅甸难民在泰国定居,他们在边境沿线建立了一系列难民营,完全依赖外部支持获得医疗和社会服务。2000 年至 2018 年间,一个国际非政府组织一直在实施一个综合初级保健项目:这项回顾性研究考察了 MCAH 的死亡率和发病率指标趋势,并将其与可持续发展目标(SDGs)指标进行了比较。对计划文件的审查探讨了初级保健服务的演变和变化情况,并对相关的项目成本进行了三角测量和分析。为核实随时间推移发生的变化,对 12 名主要信息提供者进行了访谈:尽管孕产妇死亡率(可持续发展目标 3.1)仍然高达 126.5/100,000,但儿童死亡率(可持续发展目标 3.2)和 5 岁以下儿童传染病(可持续发展目标 3.3)分别下降了 69%和 92%。孕产妇贫血症减少了 30%;90% 以上的孕妇接受了四次或四次以上的产前检查,80% 的孕妇由熟练助产士接生;剖腹产率有所上升,但仍保持在平均 3.7% 的低水平;青少年(15-19 岁)出生率在 2015 年达到峰值,为 188/1000 例,但在 2018 年降至 89/1000 例(可持续发展目标 3.7):全面提供初级保健服务,提高医疗服务提供者在儿童和青少年保健方面的能力,同时确保资金到位,是将儿童和青少年保健指标提高到可接受水平的适当策略。然而,由于难民营的局限性和特定医疗服务的分散性造成的不平等阻碍了 2030 年可持续发展目标议程 "不让一个人掉队 "的实现。2018 年,每个新生儿的成本为 115 欧元;然而,需要在更长的时期内进一步探讨 MCAH 的支出。
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引用次数: 0
Patients' experiences of and roles in interprofessional collaborative practice in primary care: a constructivist grounded theory study. 患者在初级医疗跨专业合作实践中的经历和角色:一项建构主义基础理论研究。
Pub Date : 2024-05-09 DOI: 10.1017/S1463423624000148
Alexandra R Davidson, Mark Morgan, Lauren Ball, Dianne P Reidlinger

Aim: This constructivist grounded theory study aimed to (1) explore patients' experiences of and roles in interprofessional collaborative practice for chronic conditions in primary care and (2) consider the relevance and alignment of an existing theoretical framework on patients' roles and based on the experiences of patient advocates.

Background: High-quality management of chronic conditions requires an interprofessional collaborative practice model of care considering an individual's mental, physical, and social health situation. Patients' experiences of this model in the primary care setting are relatively unknown.

Methods: A constructivist grounded theory approach was taken. Interview data were collected from primary care patients with chronic conditions across Australia in August 2020 - February 2022. Interviews were recorded, transcribed verbatim, and thematically analysed by (1) initial line-by-line coding, (2) focused coding, (3) memo writing, (4) categorisation, and (5) theme and sub-theme development. Themes and sub-themes were mapped against an existing theoretical framework to expand and confirm the results from a previous study with a similar research aim.

Findings: Twenty adults with chronic conditions spanning physical disability, diabetes, heart disease, cancer, autoimmune, and mental health conditions participated. Two themes were developed: (1) Adapting to Change with two sub-themes describing how patients adapt to interprofessional team care and (2) Shifting across the spectrum of roles, with five sub-themes outlining the roles patients enact while receiving care. The findings suggest that patients' roles are highly variable and fluid in interprofessional collaborative practice, and further work is recommended to develop a resource to support greater patient engagement in interprofessional collaborative practice.

目的:这项建构主义基础理论研究旨在:(1)探讨患者在初级医疗慢性病跨专业合作实践中的经验和角色;(2)根据患者倡导者的经验,考虑现有理论框架与患者角色的相关性和一致性:背景:高质量的慢性病管理需要一种跨专业合作实践的护理模式,这种模式要考虑到个人的心理、生理和社会健康状况。患者在初级医疗环境中对这一模式的体验相对未知:方法:采用建构主义基础理论方法。访谈数据收集于 2020 年 8 月至 2022 年 2 月期间,来自澳大利亚各地的初级医疗慢性病患者。对访谈进行记录、逐字转录,并通过以下方法进行主题分析:(1)初步逐行编码;(2)重点编码;(3)撰写备忘录;(4)分类;(5)主题和次主题发展。根据现有的理论框架对主题和次主题进行了映射,以扩展和确认以前一项具有类似研究目的的研究的结果:20 名患有慢性疾病的成年人参加了此次研究,这些慢性疾病包括身体残疾、糖尿病、心脏病、癌症、自身免疫性疾病和精神疾病。研究提出了两个主题:(1) 适应变化,其中两个子主题描述了患者如何适应跨专业团队护理;(2) 角色转换,其中五个子主题概述了患者在接受护理时所扮演的角色。研究结果表明,在跨专业合作实践中,患者的角色是高度可变和多变的,建议进一步开展工作,开发一种资源,支持患者更多地参与跨专业合作实践。
{"title":"Patients' experiences of and roles in interprofessional collaborative practice in primary care: a constructivist grounded theory study.","authors":"Alexandra R Davidson, Mark Morgan, Lauren Ball, Dianne P Reidlinger","doi":"10.1017/S1463423624000148","DOIUrl":"10.1017/S1463423624000148","url":null,"abstract":"<p><strong>Aim: </strong>This constructivist grounded theory study aimed to (1) explore patients' experiences of and roles in interprofessional collaborative practice for chronic conditions in primary care and (2) consider the relevance and alignment of an existing theoretical framework on patients' roles and based on the experiences of patient advocates.</p><p><strong>Background: </strong>High-quality management of chronic conditions requires an interprofessional collaborative practice model of care considering an individual's mental, physical, and social health situation. Patients' experiences of this model in the primary care setting are relatively unknown.</p><p><strong>Methods: </strong>A constructivist grounded theory approach was taken. Interview data were collected from primary care patients with chronic conditions across Australia in August 2020 - February 2022. Interviews were recorded, transcribed verbatim, and thematically analysed by (1) initial line-by-line coding, (2) focused coding, (3) memo writing, (4) categorisation, and (5) theme and sub-theme development. Themes and sub-themes were mapped against an existing theoretical framework to expand and confirm the results from a previous study with a similar research aim.</p><p><strong>Findings: </strong>Twenty adults with chronic conditions spanning physical disability, diabetes, heart disease, cancer, autoimmune, and mental health conditions participated. Two themes were developed: (1) <i>Adapting to Change</i> with two sub-themes describing how patients adapt to interprofessional team care and (2) <i>Shifting across the spectrum of roles</i>, with five sub-themes outlining the roles patients enact while receiving care. The findings suggest that patients' roles are highly variable and fluid in interprofessional collaborative practice, and further work is recommended to develop a resource to support greater patient engagement in interprofessional collaborative practice.</p>","PeriodicalId":74493,"journal":{"name":"Primary health care research & development","volume":"25 ","pages":"e24"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11091539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
General practitioner preferences for telehealth consultations in Australia: a pilot survey and discrete choice experiment. 澳大利亚全科医生对远程医疗咨询的偏好:试点调查和离散选择实验。
Pub Date : 2024-05-09 DOI: 10.1017/S1463423624000136
Keshia R De Guzman, Anthony C Smith, Centaine L Snoswell

Aim: To identify and quantify general practitioner (GP) preferences related to service attributes of clinical consultations, including telehealth consultations, in Australia.

Background: GPs have been increasingly using telehealth to deliver patient care since the onset of the 2019 coronavirus disease (COVID-19) pandemic. GP preferences for telehealth service models will play an important role in the uptake and sustainability of telehealth services post-pandemic.

Methods: An online survey was used to ask GPs general telehealth questions and have them complete a discrete choice experiment (DCE). The DCE elicited GP preferences for various service attributes of telehealth (telephone and videoconference) consultations. The DCE investigated five service attributes, including consultation mode, consultation purpose, consultation length, quality of care and rapport, and patient co-payment. Participants were presented with eight choice sets, each containing three options to choose from. Descriptive statistics was used, and mixed logit models were used to estimate and analyse the DCE data.

Findings: A total of 60 GPs fully completed the survey. Previous telehealth experiences impacted direct preferences towards telehealth consultations across clinical presentations, although in-person modes were generally favoured (in approximately 70% of all scenarios). The DCE results lacked statistical significance which demonstrated undiscernible differences between GP preferences for some service attributes. However, it was found that GPs prefer to provide a consultation with good quality care and rapport (P < 002). GPs would also prefer to provide care to their patients rather than decline a consultation due to consultation mode, length or purpose (P < 0.0001). Based on the findings, GPs value the ability to provide high-quality care and develop rapport during a clinical consultation. This highlights the importance of recognising value-based care for future policy reforms, to ensure continued adoption and sustainability of GP telehealth services in Australia.

目的:确定并量化澳大利亚全科医生(GP)对临床咨询(包括远程医疗咨询)服务属性的偏好:背景:自 2019 年冠状病毒病(COVID-19)大流行以来,全科医生越来越多地使用远程医疗为患者提供护理服务。全科医生对远程医疗服务模式的偏好将在大流行后远程医疗服务的吸收和可持续性方面发挥重要作用:方法:采用在线调查的方式向全科医生询问有关远程保健的一般问题,并让他们完成离散选择实验(DCE)。离散选择实验了解全科医生对远程保健(电话和视频会议)咨询的各种服务属性的偏好。离散选择实验调查了五种服务属性,包括会诊模式、会诊目的、会诊时长、护理质量和融洽关系以及患者共同付费。向参与者展示了八个选择集,每个选择集包含三个选项。研究采用了描述性统计方法,并使用混合对数模型对 DCE 数据进行估计和分析:共有 60 名全科医生完成了调查。以往的远程医疗经验直接影响了人们对各种临床表现的远程医疗会诊的偏好,尽管人们普遍偏好面对面模式(在所有情景中约占 70%)。DCE 的结果缺乏统计意义,表明全科医生对某些服务属性的偏好存在明显差异。然而,研究发现,全科医生更倾向于提供具有优质护理和融洽关系的咨询(P < 002)。全科医生也更愿意为病人提供护理,而不是因为会诊模式、会诊时间或目的而拒绝会诊(P < 0.0001)。根据研究结果,全科医生重视在临床问诊过程中提供高质量护理和建立融洽关系的能力。这凸显了在未来的政策改革中承认基于价值的护理的重要性,以确保全科医生远程医疗服务在澳大利亚的持续应用和可持续性。
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引用次数: 0
A pilot study to evaluate the quality of care in oral anticoagulant and antiplatelet use in patients with permanent atrial fibrillation in Irish general practice 评估爱尔兰全科医生对永久性心房颤动患者使用口服抗凝剂和抗血小板治疗质量的试点研究
Pub Date : 2024-04-25 DOI: 10.1017/s1463423623000622
Sarah McErlean, John Broughan, Geoff McCombe, Ronan Fawsitt, Walter Cullen, Joe Gallagher
Aim: The aim of this pilot study is to determine the pattern of oral anticoagulant and antiplatelet use in patients with permanent atrial fibrillation (AF) in Irish general practice. Background: Worldwide, AF is the most common sustained cardiac arrhythmia in adults and poses a significant burden to patients, physicians and healthcare systems. There is a five-fold increased risk of stroke with AF, and AF-related strokes are associated with higher levels of both morbidity and mortality compared to other stroke subtypes. Thankfully, appropriate use of oral anticoagulation (OAC) for AF can reduce the risk of stroke by up to 64%. However, we know that patients are commonly undertreated with OAC, prescribed inappropriate doses of OAC and have prolonged use of an antiplatelet agent in addition to OAC without indication. Methods: A descriptive, cross-sectional observational study was undertaken. Proportionate sampling was used across 11 practices from the Ireland East practice-based research network. The general practitioners completed a report form on each patient provided by the research team by undertaking a retrospective chart review. Findings: Eleven practices participated with a total number of 1855 patients with AF. We received data on 153 patients. The main findings from this pilot project are that: 1. 11% of patients were undertreated with OAC 2. 20 % of patients were on an incorrect non-vitamin K antagonist oral anticoagulant dose 3. 28 patients (18%) were inappropriately prescribed combination antithrombotic therapy Undertreatment and underdosing of OAC expose patients to higher risk of thromboembolic events, bleeding and all-cause mortality. Prolonged combination antithrombotic therapy is associated with serious increased risk of bleeding with no additional stroke protection. This pilot project highlights several gaps between guidelines and clinical practice. By identifying these areas, we hope to develop a targeted quality improvement intervention using the electronic health records in general practice to improve the care that those with AF receive.
目的:本试点研究旨在确定爱尔兰全科医生中永久性心房颤动(房颤)患者使用口服抗凝剂和抗血小板药物的模式。研究背景:在全球范围内,房颤是成年人最常见的持续性心律失常,给患者、医生和医疗保健系统带来了沉重负担。与其他中风亚型相比,房颤相关中风的发病率和死亡率均较高。值得庆幸的是,心房颤动患者适当使用口服抗凝药(OAC)可将中风风险降低 64%。然而,我们知道患者通常对 OAC 的治疗不足,开出的 OAC 剂量不当,并且在无指征的情况下除 OAC 外还长期使用抗血小板药物。研究方法进行了一项描述性横断面观察研究。在爱尔兰东部以实践为基础的研究网络中的 11 家诊所按比例抽样。全科医生通过回顾性病历审查,对研究小组提供的每位患者填写一份报告表。研究结果共有 11 家诊所参与了这项研究,共有 1855 名房颤患者。我们收到了 153 名患者的数据。该试点项目的主要发现有 11% 的患者接受的 OAC 治疗不足 2. 20% 的患者使用的非维生素 K 拮抗剂口服抗凝剂剂量不正确 3. 28 名患者(18%)接受的联合抗血栓治疗处方不当 治疗不足和 OAC 剂量不足使患者面临血栓栓塞事件、出血和全因死亡的更高风险。延长联合抗血栓治疗时间会严重增加出血风险,但对中风却没有额外的保护作用。该试点项目强调了指南与临床实践之间的一些差距。通过找出这些差距,我们希望利用全科医生的电子健康记录制定有针对性的质量改进干预措施,以改善心房颤动患者所接受的治疗。
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引用次数: 0
World Organization of National Colleges, Academies and Academic Associations of General Practitioners and Family Physicians (WONCA) Europe position paper on the use of point-of-care ultrasound (POCUS) in primary care. 世界全科医生和家庭医生国家学院、学会和学术协会组织 (WONCA) 欧洲立场文件:在初级保健中使用护理点超声波 (POCUS)。
Pub Date : 2024-04-23 DOI: 10.1017/S1463423624000112
Aaron Poppleton, Sonia Tsukagoshi, S. Vinker, Francois Heritier, P. Frappé, Fabian Dupont, Peter Sigmund, Mihai Iacob, Josep-Maria Vilaseca, Mehmet Ungan, Camilla Aakjær Andersen, Thomas Frese, David Halata
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引用次数: 1
Reforms and innovations in primary health care in different countries: scoping review. 不同国家初级卫生保健的改革与创新:范围审查。
Pub Date : 2024-04-23 DOI: 10.1017/S1463423623000725
Solmaz Azimzadeh, S. Azami-aghdash, J. Tabrizi, K. Gholipour
INTRODUCTIONThe World Health Organization (WHO) recommends focusing on primary health care (PHC) as the first strategy of countries to achieve the improvement of the health level of communities and has emphasized it again in 2021. Therefore, we intend to take a different look at the PHC system with reform, innovation, and initiative by using the experiences of leading countries and identify practical and evidence-based solutions to achieve greater health.METHODSThis is a scoping review study that has identified innovations and reforms related to PHC since the beginning of 2000 to the end of 2022. In this study, Scopus, Web Of Science, and PubMed databases have been searched using appropriate keywords. This study is done in six steps using Arkesy and O'Malley framework. In this study, the framework of six building blocks of WHO was used to summarize and report the findings.RESULTSBy searching in different databases, we identified 39426 studies related to reforms in primary care, and after the screening process, 106 studies were analyzed. Our findings were classified and reported into 9 categories (aims, stewardship/leadership, financing & payment, service delivery, health workforce, information, outcomes, policies/considerations, and limitations).CONCLUSIONThe necessity and importance of strengthening PHC is obvious to everyone due to its great consequences, which requires a lot of will, effort, and coordination at the macro-level of the country, various organizations, and health teams, as well as the participation of people and society.
引言世界卫生组织(WHO)建议将初级卫生保健(PHC)作为各国提高社区卫生水平的首要战略,并在 2021 年再次强调了这一点。因此,我们打算通过借鉴领先国家的经验,以不同的视角看待初级卫生保健系统的改革、创新和举措,并找出切实可行、以证据为基础的解决方案,以实现更高的健康水平。在本研究中,使用适当的关键词搜索了 Scopus、Web Of Science 和 PubMed 数据库。本研究采用 Arkesy 和 O'Malley 框架,分六个步骤进行。通过在不同的数据库中搜索,我们发现了 39426 项与初级保健改革相关的研究,经过筛选,对 106 项研究进行了分析。我们将研究结果分为 9 个类别(目的、管理/领导、筹资与支付、服务提供、卫生工作者队伍、信息、结果、政策/考虑因素和局限性)进行了分类和报告。结论加强初级保健的必要性和重要性不言而喻,因为它的影响巨大,需要国家、各种组织和卫生团队在宏观层面上的大量意愿、努力和协调,以及人民和社会的参与。
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引用次数: 0
Randomised controlled trial of lifestyle interventions for abdominal obesity in primary health care 基层医疗机构腹部肥胖症生活方式干预随机对照试验
Pub Date : 2024-04-19 DOI: 10.1017/s1463423624000069
Pedro Carrera-Bastos, Björn Rydhög, Maelán Fontes-Villalba, Daniel Arvidsson, Yvonne Granfeldt, Kristina Sundquist, Tommy Jönsson
Aim: Assess effects on waist circumference from diet with or without cereal grains and with or without long-term physical exercise. Background: Elevated waist circumference is an indicator of increased abdominal fat storage and is accordingly associated with increased cardiovascular mortality. This is likely due to the association between lifestyle-induced changes in waist circumference and cardiovascular risk factors. Reductions in waist circumference may be facilitated by diet without cereal grains combined with long-term physical exercise. Methods: Two-year randomised controlled trial with factorial trial design in individuals at increased risk of cardiovascular disease with increased waist circumference. Participants were allocated diet based on current Swedish dietary guidelines with or without cereal grains (baseline diet information supported by monthly group sessions) and with or without physical exercise (pedometers and two initial months of weekly structured exercise followed by written prescription of physical activity) or control group. The primary outcome was the change in waist circumference. Findings: The greatest mean intervention group difference in the change in waist circumference among the 73 participants (47 women and 26 men aged 23–79 years) was at one year between participants allocated a diet without cereal grains and no exercise and participants allocated a diet with cereal grains and no exercise [M = −5.3 cm and −0.9 cm, respectively; mean difference = 4.4 cm, 4.0%, 95% CI (0.0%, 8.0%), P = 0.051, Cohen’s d = 0.75]. All group comparisons in the change in waist circumference were non-significant despite the greatest group difference being more than double that estimated in the pre-study power calculation. The non-significance was likely caused by too few participants and a greater than expected variability in the change in waist circumference. The greatest mean intervention group difference strengthens the possibility that dietary exclusion of cereal grains could be related to greater reduction in waist circumference.
目的:评估添加或不添加谷物以及进行或不进行长期体育锻炼的饮食对腰围的影响。背景:腰围升高是腹部脂肪储存增加的指标,因此与心血管死亡率增加有关。这可能是由于生活方式引起的腰围变化与心血管风险因素之间存在关联。不含谷物的饮食加上长期体育锻炼可能有助于减少腰围。研究方法对腰围增大的心血管疾病高危人群进行为期两年的随机对照试验,采用因子试验设计。参与者被分配到根据瑞典现行膳食指南制定的饮食中添加或不添加谷物(基线饮食信息由每月小组会议提供支持),以及添加或不添加体育锻炼(计步器和最初两个月的每周结构化锻炼,随后提供书面体育锻炼处方)或对照组。主要结果是腰围的变化。研究结果在 73 名参与者(47 名女性和 26 名男性,年龄在 23-79 岁之间)中,采用不含谷物和不运动饮食的参与者与采用含谷物和不运动饮食的参与者在一年后腰围变化的平均干预组差异最大[M = -5.3 厘米和 -0.9 厘米;平均差异 = 4.4 厘米,4.0%,95% CI (0.0%, 8.0%),P = 0.051,Cohen's d = 0.75]。腰围变化的所有组间比较均不显著,尽管最大组间差异是研究前功率计算估计值的两倍多。不显著的原因可能是参与者太少,以及腰围变化的变异性超出预期。最大的平均干预组差异加强了膳食中不摄入谷物可能与腰围减少有关的可能性。
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Primary health care research & development
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