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Community pharmacist involvement in social prescribing for mental health: a qualitative study. 社区药剂师参与精神健康社会处方:一项定性研究。
Pub Date : 2024-12-20 DOI: 10.1017/S1463423624000409
Denise A Taylor, Andrea D J Taylor, Matthew Jones, Hannah E Family

Aim: We aimed to explore participant perspectives on social prescribing (SP) for mental health and well-being and the acceptability of community pharmacists (CP) as members of SP pathways that support people with mild to moderate depression and anxiety.

Background: SP aims to support people with poor health related to socio-demographic determinants. Positive effects of SP on self-belief, mood, well-being, and health are well documented, including a return to work for long-term unemployed.

Methods: The study was set in a city in southwest England with diverse cultural and socio-demographics. We recruited SP stakeholders, including CP, to either one of 17 interviews or a focus group with nine members of the public.

Findings: An inductive iterative approach to thematic analysis produced four superordinate themes: (1) offering choice a non-pharmacological option, (2) supporting pharmacy communities - 'it is an extension of what we do', (3) stakeholder perspectives - pharmacists are very busy and their expertise unknown by some, and (4) potential for pharmacy in primary care.Stakeholders viewed CP as local to and accessible by their community. Pharmacists perceived referral to SP services as part of their current role. General practitioner participants considered pharmacy involvement could reduce their workload and expand the primary healthcare team. Importantly, general practitioners and CP viewed SP as a non-pharmacological alternative to prescribing unnecessary antidepressants and reduce associated adverse effects. All participants voiced concerns about pharmacy dispensing busyness as a potential barrier to involvement and pharmacists requesting mental health training updates.Key findings suggest CP offer a potential alternative to the general practitioner for people with mild to moderate depression and anxiety seeking access to support and health information. However, CP need appropriately commissioned and funded involvement in SP, including backfill for ongoing dispensing, medicines optimization, and mental health first aid training.

目的:本研究旨在探讨社会处方(SP)对心理健康和福祉的影响,以及社区药剂师(CP)作为支持轻至中度抑郁和焦虑患者的SP途径成员的可接受性。背景:SP旨在支持与社会人口决定因素有关的健康状况不佳的人。SP对自信、情绪、幸福感和健康的积极影响是有案可查的,包括长期失业的人重返工作岗位。方法:本研究设置在英格兰西南部一个具有不同文化和社会人口统计学特征的城市。我们招募了包括CP在内的SP利益相关者参加17次访谈或与9名公众成员进行焦点小组讨论。结果:主题分析的归纳迭代方法产生了四个高级主题:(1)提供非药物选择,(2)支持药房社区-“这是我们所做的事情的延伸”,(3)利益相关者的观点-药剂师非常忙碌,他们的专业知识被一些人所知,(4)初级保健药房的潜力。利益相关者认为CP是本地的,他们的社区可以使用。药剂师认为转诊到SP服务是他们当前角色的一部分。全科医生参与者认为药房的参与可以减少他们的工作量并扩大初级保健团队。重要的是,全科医生和CP将SP视为处方不必要的抗抑郁药的非药物替代,并减少相关的不良反应。所有参与者都表达了对药房配药繁忙的担忧,认为这是参与的潜在障碍,药剂师要求更新心理健康培训。主要发现表明,对于寻求支持和健康信息的轻度至中度抑郁和焦虑患者,CP提供了一个潜在的替代全科医生。然而,CP需要适当地委托和资助SP的参与,包括正在进行的配药回填,药物优化和心理健康急救培训。
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引用次数: 0
Early detection efforts for colorectal and prostate cancer from the patient's perspective over the course of 12 years: results of the KABOT survey study. 从患者角度看 12 年间结直肠癌和前列腺癌的早期检测工作:KABOT 调查研究的结果。
Pub Date : 2024-12-16 DOI: 10.1017/S1463423624000653
Kay-Patrick Braun, Julia Maurer, Ingmar Wolff, Torsten Vogel, Steffen Lebentrau, Matthias May, Markus Herrmann

Aim: This study investigates the level of knowledge and utilization of colorectal cancer (CRC) and prostate cancer (PCa) early detection measures (EDMs) over a period of 12 years in general practice from the patient's perspective.

Background: The role of general practitioners (GPs) in EDMs for CRC and PCa in Germany is not well-documented with comprehensive data.

Methods: We conducted a patient-centric survey in the German federal state of Berlin-Brandenburg at a 12-year interval to examine the role of GPs in EDMs for CRC and PCa. In 2009, 55 GPs were tasked with informing 50 consecutive male patients, each aged over 35, about participating in a survey study (study phase 1/SP1). To evaluate changes over 12 years, a new survey involving 50 male patients from each of 150 GPs was conducted from October 2021 to March 2022 (SP2).

Findings: We thoroughly reviewed the questionnaires of 890 patients, with 755 in SP1 and 135 in SP2. Patients showed greater awareness of recommendations regarding colonoscopy compared to prostate-specific antigen (PSA) testing. GPs were the most frequently reported source of information for both EDMs in our cohort. Comparing the two study phases, no significant difference in specific awareness of colonoscopy or PSA testing was found among men eligible for EDMs. However, there was a notable increase in the role of health insurance companies as a source of information about colonoscopy over time. Nearly 60% of included patients underwent colonoscopy and/or PSA testing as EDMs.

Conclusion: The number of EDMs performed among study participants did not increase over time. Our study confirms that GPs remain the primary source of information about EDMs among the study participants.

目的:本研究从患者的角度出发,调查了12年间全科医生对结直肠癌(CRC)和前列腺癌(PCa)早期检测措施(EDM)的了解程度和使用情况:背景:在德国,全科医生(GPs)在儿童癌症(CRC)和前列腺癌(PCa)早期诊断措施(EDMs)中所扮演的角色并没有全面的数据记录:方法:我们在德国联邦柏林-勃兰登堡州进行了一项以患者为中心的调查,每隔 12 年对全科医生在 CRC 和 PCa 的 EDM 中的作用进行一次研究。2009 年,55 名全科医生受命通知 50 名年龄在 35 岁以上的男性患者参加调查研究(研究阶段 1/SP1)。为了评估12年来的变化,我们在2021年10月至2022年3月期间进行了一项新的调查,150名全科医生中的每一位都有50名男性患者参与调查(SP2):我们全面审查了 890 名患者的调查问卷,其中 755 人参与了 SP1,135 人参与了 SP2。与前列腺特异性抗原 (PSA) 检测相比,患者对结肠镜检查建议的了解程度更高。在我们的队列中,全科医生是两种 EDM 最常见的信息来源。比较两个研究阶段,我们发现符合 EDM 条件的男性对结肠镜检查或 PSA 检测的具体了解程度没有明显差异。不过,随着时间的推移,医疗保险公司作为结肠镜检查信息来源的作用明显增强。近60%的纳入患者接受了结肠镜检查和/或PSA检测作为EDM:结论:研究参与者中接受 EDM 的人数并未随着时间的推移而增加。我们的研究证实,全科医生仍然是研究参与者中有关 EDM 的主要信息来源。
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引用次数: 0
How should policymakers, funders, and research teams mobilize to build the evidence base on universal early years services? 政策制定者、资助者和研究团队应如何动员起来,建立普及幼儿服务的证据基础?
Pub Date : 2024-12-10 DOI: 10.1017/S1463423624000550
Katie Harron, Sally Kendall, Catherine Bunting, Rebecca Cassidy, Julie Atkins, Amanda Clery, Eirini-Christina Saloniki, Francesca Cavallaro, Helen Bedford, Louise Mc Grath-Lone, Mengyun Liu, Jenny Woodman

Health visiting in England is a universal service that aims to promote the healthy development of children aged under five years and safeguard their welfare. We consulted stakeholders about their priorities for research into health visiting and also used these consultations and a literature review to generate a logic model. Parents wanted research to explore how health visiting teams can provide a caring, responsive, accessible service (the mechanisms of change). Policymakers, commissioners, and clinical service leads wanted descriptions and evaluations of currently implemented and 'gold standard' health visiting. The challenges to evaluating health visiting (data quality, defining the intervention, measuring appropriate outcomes, and estimating causal effects) mean that quasi-experimental studies that rely on administrative data will likely underestimate impact or even fail to detect impact where it exists. Prospective and experimental studies are needed to understand how health visiting influences infant-parent attachments, breastfeeding, childhood accidents, family nutrition, school readiness, and mental health and well-being.

在英格兰,健康访视是一项普遍服务,旨在促进五岁以下儿童的健康成长并保障他们的福利。我们就健康访视研究的优先事项咨询了利益相关者,并利用这些咨询和文献综述生成了一个逻辑模型。家长们希望通过研究来探讨健康访视团队如何能够提供关怀备至、反应迅速、易于获得的服务(变革机制)。政策制定者、专员和临床服务负责人希望对目前实施的 "黄金标准 "健康访视进行描述和评估。健康访视评估所面临的挑战(数据质量、干预措施的定义、适当结果的测量以及因果效应的估算)意味着,依赖于行政数据的准实验性研究很可能会低估其影响,甚至无法发现其存在的影响。我们需要开展前瞻性和实验性研究,以了解健康访视如何影响婴儿与父母的依恋关系、母乳喂养、儿童意外事故、家庭营养、入学准备以及心理健康和幸福。
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引用次数: 0
A plan to transform primary and community care at Catalonia based on a process improvement methodology. 在过程改进方法的基础上改造加泰罗尼亚初级和社区保健的计划。
Pub Date : 2024-12-02 DOI: 10.1017/S1463423624000604
Marc Sales Coll, Sara Manjón, Jeroni Salabert, Clara Pladevall, Daniel Algar, Alba Benaque, Júlia Soler, Anna Ochoa de Echagüen Aguilar

Aim: This article outlines the implementation and deployment strategy defined by the Catalan healthcare system which sought to promote a plan to strengthen and transform primary care in order to provide high-quality healthcare services whilst making an optimal use of resources across the Catalan region.

Background: Following the COVID-19 pandemic, the Catalan healthcare system initiated a plan to enhance primary care services. The Lean methodology has been used extensively in other sectors for process improvement. More recently, it has been adopted in large hospitals, showing good results, so Lean was selected as the most appropriate method to achieve this project's goal. The Process Office of the Catalan Health System, which is made up of experts in Lean methodology, has been involved in defining and deploying the strategy to all 374 Primary Care Teams (PCTs) within the Catalan healthcare system.

Methods: The deployment strategy was executed in four phases (each consisting of a number of sessions): (1) explaining the project's goals and training the professionals in the methodology; (2) assessing the current status regarding the processes with the various PCTs; (3) identifying and implementing improvement projects; and (4) defining key performance indicators to monitor the impact of the projects.

Findings: As a conclusion, this project has allowed to successfully define and implement a standard at a strategic and deployment level of a project for primary care improvement that may be replicated in other regions. The key elements to ensure success have been the following: leadership, implementation of an improvement methodology, standardization of sessions, and involvement and training of front-line professionals.

目的:本文概述了加泰罗尼亚医疗保健系统定义的实施和部署战略,旨在促进加强和改造初级保健的计划,以提供高质量的医疗保健服务,同时优化利用加泰罗尼亚地区的资源。背景:在2019冠状病毒病大流行之后,加泰罗尼亚卫生保健系统启动了一项加强初级保健服务的计划。精益方法已广泛应用于其他部门的过程改进。最近,它已经被大型医院采用,并取得了良好的效果,因此选择精益作为最合适的方法来实现这个项目的目标。由精益方法专家组成的加泰罗尼亚卫生系统流程办公室参与了加泰罗尼亚卫生系统内所有374个初级保健小组(pct)的战略定义和部署。方法:部署策略分四个阶段执行(每个阶段由若干次会议组成):(1)解释项目目标并培训方法方面的专业人员;(2)评估各pct进程的现状;(3)确定和实施改进项目;(4)确定关键绩效指标,以监测项目的影响。研究结果:作为结论,该项目成功地在战略和部署层面定义和实施了一个改善初级保健项目的标准,这可以在其他地区复制。确保成功的关键因素如下:领导、改进方法的实施、会议的标准化以及一线专业人员的参与和培训。
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引用次数: 0
Healthy ageing in long-term care? Lessons learned from the COVID-19 pandemic: a position paper. 长期护理中的健康老龄化?2019冠状病毒病大流行的经验教训:立场文件。
Pub Date : 2024-11-29 DOI: 10.1017/S1463423624000598
Frode F Jacobsen, Stinne Glasdam, Heidi Haukelien, Maria E T C van den Muijsenbergh, Gudmund Ågotnes
<p><strong>Aim: </strong>This position paper focuses on healthy ageing for the frailest and institutionalized older adults in the context of the recent pandemic. The paper aims to identify and discuss hindering and promoting factors for healthy ageing in this context, taking both health safety and a meaningful social life into account, in a pandemic situation and beyond.</p><p><strong>Background: </strong>The recent COVID-19 pandemic has highlighted the vulnerability of frail older adults residing in long-term care institutions. This is a segment of the older population that does not seem to align well with the recent policy trend of healthy and active ageing. The need for healthy ageing in this population has been voiced by professionals and interest organizations alike, alluding to inadequate support systems during the pandemic, conditioned by both previous and newly emerging contextual factors. Supporting healthy ageing in older adults in nursing homes and other residential care settings calls for attending to meaningful social life as well as to disease control.</p><p><strong>Methods: </strong>Findings and early conclusions leading up to the position paper were presented with peer discussions involving healthcare professionals and researchers at two joint EFPC PRIMORE workshops 2021 and 2022, as well as other international research seminars on long-term care. The following aspects of long-term care and COVID-19 were systematically discussed in those events, with reference to relevant research literature: 1. Long-term care policies, 2. pre-COVID state of long-term care facilities and vulnerability to the pandemic, 3. factors influencing the extent of spread of infection in long-term care facilities, and 4. the challenge of balancing between strict measures for infection control and maintaining a meaningful social life for residents and their significant others.</p><p><strong>Findings: </strong>A policy shift towards ageing at home and supporting the healthiest of older adults seems to have had unwarranted effects both for frail older adults, their significant others, and professional care staff attending to their needs. Resulting insufficient investment in primary health care staff and in the built environment for frail older adults in nursing homes were detrimental both for the older adults living in nursing homes, their significant others, and staff. More investment in staff and in physical surroundings might improve the quality of care and the social life of older adults in nursing homes in a non-pandemic situation and be a resource for primary health care staff ensuring both protection from health hazards and a meaningful social life for frail older adults in a pandemic or epidemic situation. As for investing in the physical surroundings, smaller nursing homes are advantageous, with singular resident rooms and for developing out-and indoor spaces for socializing and for meeting with families and other visitors. Regarding investment in staf
目的:本立场文件的重点是在最近大流行的背景下,最脆弱和被收容的老年人的健康老龄化问题。本文旨在确定和讨论在这种情况下阻碍和促进健康老龄化的因素,同时考虑到健康安全和有意义的社会生活,在流行病的情况下和超越。背景:最近的COVID-19大流行凸显了居住在长期护理机构的体弱老年人的脆弱性。这部分老年人口似乎不太符合最近健康和积极老龄化的政策趋势。专业人员和利益组织都表达了这一人群健康老龄化的必要性,暗指疫情期间支持系统不足,受到以往和新出现的背景因素的制约。支持养老院和其他住宿护理机构的老年人健康老龄化需要参加有意义的社会生活以及疾病控制。方法:在2021年和2022年两次EFPC PRIMORE联合研讨会以及其他关于长期护理的国际研究研讨会上,医疗保健专业人员和研究人员进行了同行讨论,并提出了导致立场文件的研究结果和早期结论。在这些事件中,参考相关研究文献,系统探讨了长期护理与COVID-19的以下方面:2.长期护理政策;2 .长期护理设施在covid - 19前的状况和对大流行的脆弱性;3 .影响长期护理机构感染传播程度的因素;在严格的感染控制措施和维持居民及其重要他人有意义的社交生活之间取得平衡的挑战。研究结果:政策转向在家养老和支持最健康的老年人,似乎对体弱多病的老年人、他们的另一半和照顾他们需求的专业护理人员都产生了不必要的影响。因此,对初级卫生保健人员的投资不足,对养老院中体弱老年人的建筑环境的投资不足,对住在养老院的老年人、他们的另一半和工作人员都是不利的。在工作人员和实际环境方面进行更多投资,可能会在非大流行病情况下改善养老院老年人的护理质量和社会生活,并成为初级保健工作人员的一种资源,确保在大流行病或流行病情况下保护体弱多病的老年人免受健康危害和有意义的社会生活。至于对物理环境的投资,较小的养老院是有利的,有单独的居住房间,并开发室外和室内空间,用于社交和会见家人和其他访客。关于对工作人员的投资,有文件证明需要受过教育的全职工作人员。应限制使用非全时或临时工作人员。
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引用次数: 0
Early structured communication between general practitioner, sick-listed patient, and employer: Results and lessons learned from a pragmatic trial in the Capacity Note project. 全科医生、病历病人和雇主之间的早期结构化沟通:从 "能力说明 "项目的实用试验中获得的结果和经验教训。
Pub Date : 2024-11-28 DOI: 10.1017/S1463423624000574
Paula Nordling, Chioma Nwaru, Lena Nordeman, Ingmarie Skoglund, Maria E H Larsson, Cecilia Björkelund, Gunnel Hensing

Background and objective: Early and collaborative interventions are desirable to prevent long-term sick leave and promote sustainable return-to-work (RTW). The aim of this study was to evaluate if the use of the Capacity Note - a brief intervention promoting early and structured communication between general practitioners (GPs), patients, and employers - had an impact on length of sick leave in patients with common mental disorders (CMDs) in primary healthcare.

Method: In a pragmatic trial, GPs at eight primary healthcare centres were randomized to provide the intervention or control and recruited eligible patients: employed women and men, 18-64 years, who visited a GP due to CMD and became or were (<4 months) full- or part-time sick-listed. Patients in the intervention group (n=28) used the Capacity Note in addition to usual care. Patients in the control group (n=28) received usual care. Outcomes of interest were time until full RTW, sick leave status at end of follow-up (17 months), number of sick leave episodes during follow-up, and number of sick leave days at 6, 12, and 17 months of follow-up.

Results: The proportion of patients with full RTW at the end of follow-up was 79.2% in the intervention group and 84.6% in the control group. Time until full RTW was 102 and 90 days (median) in intervention and control group, respectively. We found no statistically significant differences between the groups for any of the outcomes.

Discussion: Despite efforts to increase the number of participants, the study ended up with a small sample. This prohibited us from drawing any final conclusions about the effect of the intervention. Obstacles to recruitment of patients and use of the intervention are discussed.

背景和目的:为预防长期病假并促进可持续的重返工作岗位(RTW),最好及早采取合作性干预措施。本研究旨在评估 "能力说明"(一种促进全科医生(GP)、患者和雇主之间进行早期、有序沟通的简短干预措施)的使用是否会对初级医疗保健中常见精神障碍(CMDs)患者的病假时间产生影响:在一项实用性试验中,8 个初级医疗保健中心的全科医生被随机分配到提供干预或对照组,并招募了符合条件的患者:18-64 岁的在职男女,因常见精神障碍而就诊于全科医生,并成为或正在成为常见精神障碍患者:在随访结束时,干预组完全复工的患者比例为 79.2%,对照组为 84.6%。干预组和对照组的完全复工时间分别为 102 天和 90 天(中位数)。我们发现干预组和对照组在任何结果上都没有统计学意义上的显著差异:讨论:尽管我们努力增加参与人数,但这项研究的样本量仍然很小。讨论:尽管我们努力增加参与人数,但研究的样本仍然较少,这使我们无法就干预效果得出任何最终结论。本文还讨论了招募患者和使用干预措施的障碍。
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引用次数: 0
The impact of COVID-19 on referrals among general practitioners and specialists in Shanghai, China. COVID-19 对中国上海全科医生和专科医生转诊的影响。
Pub Date : 2024-11-20 DOI: 10.1017/S1463423624000525
Zhongqing Xu, Jingchun Fan, Dandan Shi, Jingjing Ding, Jun Zhou, Xianzhen Feng, Brett D Hambly, Kun Tao, Shisan Bao

Background: The COVID-19 pandemic has impacted patient's visits to general practitioners (GPs). However, it is unclear what the impact of COVID-19 has been on the interaction among the local primary care clinics, the GP Department within the hospital and specialists.

Methods: The interaction among GPs referring to hospital-based specialists and specialists to local doctors was determined, comparing pre-pandemic 2019 and 2020 during the pandemic.

Results: Reduced referrals from GPs to specialists were consistent with the reduction in specialist referrals back to the local doctors, which dropped by approximately 50% in 2020, particularly in the two most common chronic conditions (hypertension and diabetes mellitus).

Discussion: Reduced referral of patients from local clinics to Tongren Hospital is probably due to the extensive online training provided to the local GPs to become more competent in handling local patients via telehealth. Our data provide some insight to assist in combatting the pandemic of COVID-19, offering objective evidence of the impact of COVID-19 on patient management by GPs.

背景:COVID-19 大流行影响了病人去看全科医生(GP)。然而,目前还不清楚 COVID-19 对当地初级保健诊所、医院内的全科医生部门和专科医生之间的互动有何影响:方法:比较大流行前的 2019 年和大流行期间的 2020 年,确定全科医生向医院专科医生转诊和专科医生向当地医生转诊之间的互动情况:结果:全科医生向专科医生转诊的减少与专科医生向当地医生转诊的减少是一致的,2020 年专科医生向当地医生的转诊减少了约 50%,尤其是两种最常见的慢性病(高血压和糖尿病):讨论:当地诊所向铜仁医院转诊的病人减少,可能是由于当地全科医生接受了广泛的在线培训,以提高通过远程医疗处理当地病人的能力。我们的数据提供了COVID-19对全科医生管理病人的影响的客观证据,为对抗COVID-19的流行提供了一些启示。
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引用次数: 0
The unrevealed links: periodontal health, human milk composition, and infant gut microbiome dynamics. 未揭示的联系:牙周健康、母乳成分和婴儿肠道微生物群动态。
Pub Date : 2024-11-14 DOI: 10.1017/S1463423624000215
Rana Badewy, Michael Glogauer, Kristin L Connor, Michael Sgro, Jim Yuan Lai, Richard P Bazinet, Howard C Tenenbaum, Amir Azarpazhooh

Aim: This review aims to identify the mechanistic relationships related to periodontal diseases and its possible association with changes in human milk composition and the composition and function of infants' gut microbiome.

Background: Maternal health conditions, especially inflammatory, are associated with altered human milk composition. It is not known whether maternal oral inflammatory diseases, including periodontal diseases, deleteriously affect human milk composition.

Methods: A narrative review was conducted according to SANRA, the Scale for the Assessment of Narrative Review Articles, guidelines. PubMed, Google Scholar, and Cochrane database of systematic reviews were searched from September 2019 up to December 2023 using keywords such as breast/human milk, maternal health/infections, and periodontal diseases. Reference lists of relevant articles were also screened. Our primary outcome of interest was human milk composition (i.e., any changes in macronutrients, immunological components, etc.). Secondary outcomes included changes in human milk microbiome and subsequent changes in the infant gut microbiome. Outcomes were synthesized using a narrative approach where the existing evidence and current literature were summarized. No risk of bias assessment of the studies was performed in this review.

Findings: The search yielded no studies investigating the relationship between periodontal diseases in nursing mothers and changes in human milk composition. However, a dose-response relationship exists between the severity of periodontal diseases and the risk of adverse pregnancy outcomes such as preterm birth. Mastitis and diabetes affected milk lipids. Immunoglobulin A (sIgA) was increased in mastitis, whereas reduced concentrations were reported in diabetes. Potential biological pathways through which periodontal diseases can negatively affect human milk composition include the systemic dissemination of inflammatory cytokines like IL-6, PGE2, and tumor necrosis factor (TNF)-β that can be up-regulated by bacterial by-products. This biological plausibility needs to be investigated, given the potentially negative impact on the quality of human milk that could be caused by periodontal inflammation.

目的:本综述旨在确定与牙周疾病有关的机理关系及其与母乳成分变化和婴儿肠道微生物组的组成和功能可能存在的关联:背景:产妇的健康状况,尤其是炎症,与母乳成分的改变有关。母体口腔炎症性疾病(包括牙周病)是否会对母乳成分产生有害影响尚不清楚:方法:根据 SANRA(叙事性综述文章评估量表)指南进行叙事性综述。使用母乳/人乳、孕产妇健康/感染和牙周疾病等关键词,检索了2019年9月至2023年12月期间的PubMed、谷歌学术和Cochrane系统综述数据库。同时还筛选了相关文章的参考文献列表。我们关注的主要结果是母乳成分(即常量营养素、免疫成分等的任何变化)。次要结果包括母乳微生物组的变化以及婴儿肠道微生物组的后续变化。研究结果采用叙述式方法进行综合,对现有证据和当前文献进行总结。本综述未对研究进行偏倚风险评估:检索结果显示,没有研究调查了哺乳期母亲牙周疾病与母乳成分变化之间的关系。然而,牙周病的严重程度与早产等不良妊娠结局的风险之间存在剂量反应关系。乳腺炎和糖尿病会影响乳脂。乳腺炎患者的免疫球蛋白 A(sIgA)会升高,而糖尿病患者的免疫球蛋白 A 浓度会降低。牙周病可能对母乳成分产生负面影响的潜在生物学途径包括炎性细胞因子(如 IL-6、PGE2 和肿瘤坏死因子 (TNF)-β 等)的全身传播,而细菌的副产品可能会上调这些细胞因子。鉴于牙周炎症可能会对母乳质量造成负面影响,因此有必要对这种生物合理性进行研究。
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引用次数: 0
Primary healthcare as a strategy for eliminating hepatitis C: the METRIC toolkit. 作为消除丙型肝炎战略的初级医疗保健:METRIC 工具包。
Pub Date : 2024-11-07 DOI: 10.1017/S1463423624000355
Ricardo Baptista-Leite, Henrique Lopes, Diogo Franco, Timo Clemens, Helmut Brand

Aim: This paper presents the development of the METRIC toolkit, aimed at enhancing primary healthcare interventions in the context of hepatitis C control, thus contributing to the World Health Organization's global strategy to achieve the elimination of the disease by 2030.

Background: At the global level, most people living with hepatitis C are unaware of their condition. As such, the eradication of hepatitis C necessitates comprehensive strategies within primary healthcare settings, as it provides an opportunity to reach the general population, facilitates the identification of potential patients who may be unfamiliar with hepatitis C, and guides them toward adequate care. Herein, we propose the METRIC toolkit as a means to optimize the efficiency and efficacy of healthcare services dedicated to hepatitis C control.

Methods: The development of the METRIC toolkit was guided by a thorough review of pertinent literature, focusing on primary healthcare interventions in hepatitis C control. Key components were identified, encompassing systematic problem identification, solution formulation, outcome evaluation, and feedback integration.

Findings: The METRIC toolkit represents a valuable resource for strengthening primary healthcare interventions in hepatitis C control. By fostering a culture of continuous improvement and data-driven decision-making, this framework holds promise in advancing the global agenda towards hepatitis C elimination. However, its successful application requires careful consideration of contextual factors and ongoing adaptation to local needs and circumstances.

目的:本文介绍了 METRIC 工具包的开发情况,该工具包旨在加强丙型肝炎控制方面的初级医疗保健干预措施,从而为世界卫生组织到 2030 年消除丙型肝炎的全球战略做出贡献:背景:在全球范围内,大多数丙型肝炎患者都不了解自己的病情。因此,要根除丙型肝炎,就必须在初级医疗保健环境中采取全面的策略,因为这为接触普通人群提供了机会,有利于识别可能对丙型肝炎不熟悉的潜在患者,并引导他们接受适当的治疗。在此,我们建议将 METRIC 工具包作为优化丙型肝炎控制医疗服务效率和效果的一种手段:方法:在开发 METRIC 工具包的过程中,我们对相关文献进行了全面回顾,重点关注丙型肝炎控制中的初级医疗保健干预措施。研究结果:METRIC 工具包的开发以对丙型肝炎控制方面的初级医疗保健干预措施的相关文献进行全面回顾为指导,确定了包括系统性问题识别、解决方案制定、结果评估和反馈整合在内的关键组成部分:METRIC 工具包是加强丙型肝炎控制的初级医疗保健干预措施的宝贵资源。通过培养持续改进和数据驱动决策的文化,该框架有望推动全球消除丙型肝炎的议程。然而,要成功应用该框架,就必须认真考虑环境因素,并不断根据当地需求和情况进行调整。
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引用次数: 0
The current state of primary healthcare in Pakistan: a way forward for low-to-middle income countries. 巴基斯坦初级保健现状:中低收入国家的前进之路。
Pub Date : 2024-10-31 DOI: 10.1017/S1463423624000549
Syed Hassan Ahmed, Maha Zahid, Summaiyya Waseem, Amna Zafar, Taha Gul Shaikh, Taha Sabri, Ainan Arshad

Background: Primary healthcare (PHC) plays a crucial role in improving health outcomes and reducing healthcare burden, especially in low-to-middle-income countries (LMICs). However, PHC has not received adequate attention in Pakistan despite its recognized importance. This study aims to examine the current state of PHC in Pakistan, identifying factors compromising its quality and effectiveness.

Methods: To find relevant data, the authors conducted a thorough literature search on PubMed, Google Scholar, and Cochrane Library from inception till 2 July 2022, without any language restriction. The following keywords were employed during the literature search, separated by Boolean operators AND, OR: "Primary Healthcare", "PHC", "Healthcare primary", "Primary Health", and "Pakistan".

Results: Pakistan's PHC infrastructure shows promise, with a considerable number of healthcare facilities in place. However, various factors hinder its effectiveness and compromise the quality of care provided. Insufficient investment, resource constraints, inadequate training of healthcare providers, lack of oversight, and limited access to essential medicines and equipment are some of the key challenges observed. Improving PHC in Pakistan is vital for addressing the population's healthcare needs, particularly in rural areas. Adequate investment, enhanced training programs, improved oversight mechanisms, and increased availability of essential resources are necessary to strengthen the PHC system. By prioritizing PHC and addressing the identified challenges, Pakistan can enhance healthcare access, reduce healthcare burden, and improve overall health outcomes for its population.

Conclusion: It is high time LMICs like Pakistan recognize PHC as the most economically feasible pathway toward accomplishing healthcare targets and adopt adequate measures to elevate its standards.

背景:初级医疗保健(PHC)在改善医疗效果和减轻医疗负担方面发挥着至关重要的作用,尤其是在中低收入国家(LMICs)。然而,尽管初级卫生保健的重要性已得到公认,但在巴基斯坦却没有得到足够的重视。本研究旨在考察巴基斯坦初级保健的现状,找出影响其质量和效果的因素:为了找到相关数据,作者在 PubMed、谷歌学术和 Cochrane 图书馆上进行了全面的文献检索,搜索时间从开始到 2022 年 7 月 2 日,没有任何语言限制。在文献检索过程中使用了以下关键词,并用布尔运算符 AND、OR 分隔:"初级卫生保健"、"初级卫生保健"、"初级卫生保健"、"初级卫生 "和 "巴基斯坦":巴基斯坦的初级保健基础设施前景广阔,拥有大量医疗设施。然而,各种因素阻碍了其有效性并影响了所提供医疗服务的质量。投资不足、资源限制、对医疗服务提供者的培训不足、缺乏监督以及基本药物和设备的获取途径有限,都是我们观察到的一些主要挑战。改善巴基斯坦的初级保健服务对于满足人民的医疗保健需求至关重要,尤其是在农村地区。充足的投资、强化的培训计划、改进的监督机制以及更多的基本资源是加强初级保健系统的必要条件。通过优先发展初级卫生保健并应对已确定的挑战,巴基斯坦可以提高医疗服务的可及性、减轻医疗负担并改善其人口的总体健康状况:巴基斯坦等低收入与中等收入国家应认识到初级卫生保健是实现医疗保健目标的最经济可行的途径,并采取适当措施提高其标准。
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引用次数: 0
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Primary health care research & development
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