Pub Date : 2013-12-31DOI: 10.1109/acc.2013.6580125
P Lopes Dos Santos, Sunil Deshpande, Daniel E Rivera, T-P Azevedo-Perdicoúlis, J A Ramos, Jarred Younger
There is good evidence that naltrexone, an opioid antagonist, has a strong neuroprotective role and may be a potential drug for the treatment of fibromyalgia. In previous work, some of the authors used experimental clinical data to identify input-output linear time invariant models that were used to extract useful information about the effect of this drug on fibromyalgia symptoms. Additional factors such as anxiety, stress, mood, and headache, were considered as additive disturbances. However, it seems reasonable to think that these factors do not affect the drug actuation, but only the way in which a participant perceives how the drug actuates on herself. Under this hypothesis the linear time invariant models can be replaced by State-Space Affine Linear Parameter Varying models where the disturbances are seen as a scheduling signal signal only acting at the parameters of the output equation. In this paper a new algorithm for identifying such a model is proposed. This algorithm minimizes a quadratic criterion of the output error. Since the output error is a linear function of some parameters, the Affine Linear Parameter Varying system identification is formulated as a separable nonlinear least squares problem. Likewise other identification algorithms using gradient optimization methods several parameter derivatives are dynamical systems that must be simulated. In order to increase time efficiency a canonical parametrization that minimizes the number of systems to be simulated is chosen. The effectiveness of the algorithm is assessed in a case study where an Affine Parameter Varying Model is identified from the experimental data used in the previous study and compared with the time-invariant model.
{"title":"Identification of Affine Linear Parameter Varying Models for Adaptive Interventions in Fibromyalgia Treatment.","authors":"P Lopes Dos Santos, Sunil Deshpande, Daniel E Rivera, T-P Azevedo-Perdicoúlis, J A Ramos, Jarred Younger","doi":"10.1109/acc.2013.6580125","DOIUrl":"https://doi.org/10.1109/acc.2013.6580125","url":null,"abstract":"<p><p>There is good evidence that naltrexone, an opioid antagonist, has a strong neuroprotective role and may be a potential drug for the treatment of fibromyalgia. In previous work, some of the authors used experimental clinical data to identify input-output linear time invariant models that were used to extract useful information about the effect of this drug on fibromyalgia symptoms. Additional factors such as anxiety, stress, mood, and headache, were considered as additive disturbances. However, it seems reasonable to think that these factors do not affect the drug actuation, but only the way in which a participant perceives how the drug actuates on herself. Under this hypothesis the linear time invariant models can be replaced by State-Space Affine Linear Parameter Varying models where the disturbances are seen as a scheduling signal signal only acting at the parameters of the output equation. In this paper a new algorithm for identifying such a model is proposed. This algorithm minimizes a quadratic criterion of the output error. Since the output error is a linear function of some parameters, the Affine Linear Parameter Varying system identification is formulated as a separable nonlinear least squares problem. Likewise other identification algorithms using gradient optimization methods several parameter derivatives are dynamical systems that must be simulated. In order to increase time efficiency a canonical parametrization that minimizes the number of systems to be simulated is chosen. The effectiveness of the algorithm is assessed in a case study where an Affine Parameter Varying Model is identified from the experimental data used in the previous study and compared with the time-invariant model.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2013 ","pages":"1976-1981"},"PeriodicalIF":0.0,"publicationDate":"2013-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/acc.2013.6580125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32076005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-06-01Epub Date: 2013-08-16DOI: 10.1109/ACC.2013.6579926
Terrell Bennett, Roozbeh Jafari, Nicholas Gans
In this work, we present a novel method to estimate joint angles and distance traveled by a human while walking. We model the human leg as a two-link revolute robot. Inertial measurement sensors placed on the thigh and shin provide the required measurement inputs. The model and inputs are then used to estimate the desired state parameters associated with forward motion using an extended Kalman filter (EKF). Experimental results with subjects walking in a straight line show that distance walked can be measured with accuracy comparable to a state of the art motion tracking systems. The EKF had an average RMSE of 7 cm over the trials with an average accuracy of greater than 97% for linear displacement.
{"title":"An Extended Kalman Filter to Estimate Human Gait Parameters and Walking Distance.","authors":"Terrell Bennett, Roozbeh Jafari, Nicholas Gans","doi":"10.1109/ACC.2013.6579926","DOIUrl":"10.1109/ACC.2013.6579926","url":null,"abstract":"<p><p>In this work, we present a novel method to estimate joint angles and distance traveled by a human while walking. We model the human leg as a two-link revolute robot. Inertial measurement sensors placed on the thigh and shin provide the required measurement inputs. The model and inputs are then used to estimate the desired state parameters associated with forward motion using an extended Kalman filter (EKF). Experimental results with subjects walking in a straight line show that distance walked can be measured with accuracy comparable to a state of the art motion tracking systems. The EKF had an average RMSE of 7 cm over the trials with an average accuracy of greater than 97% for linear displacement.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2013 ","pages":"752-757"},"PeriodicalIF":0.0,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363411/pdf/nihms847706.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34856690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1109/acc.2013.6580124
Yuwen Dong, Daniel E Rivera, Danielle S Downs, Jennifer S Savage, Diana M Thomas, Linda M Collins
Excessive gestational weight gain (GWG) represents a major public health issue. In this paper, we pursue a control engineering approach to the problem by applying model predictive control (MPC) algorithms to act as decision policies in the intervention for assigning optimal intervention dosages. The intervention components consist of education, behavioral modification and active learning. The categorical nature of the intervention dosage assignment problem dictates the need for hybrid model predictive control (HMPC) schemes, ultimately leading to improved outcomes. The goal is to design a controller that generates an intervention dosage sequence which improves a participant's healthy eating behavior and physical activity to better control GWG. An improved formulation of self-regulation is also presented through the use of Internal Model Control (IMC), allowing greater flexibility in describing self-regulatory behavior. Simulation results illustrate the basic workings of the model and demonstrate the benefits of hybrid predictive control for optimized GWG adaptive interventions.
{"title":"Hybrid Model Predictive Control for Optimizing Gestational Weight Gain Behavioral Interventions.","authors":"Yuwen Dong, Daniel E Rivera, Danielle S Downs, Jennifer S Savage, Diana M Thomas, Linda M Collins","doi":"10.1109/acc.2013.6580124","DOIUrl":"10.1109/acc.2013.6580124","url":null,"abstract":"<p><p>Excessive gestational weight gain (GWG) represents a major public health issue. In this paper, we pursue a control engineering approach to the problem by applying model predictive control (MPC) algorithms to act as decision policies in the intervention for assigning optimal intervention dosages. The intervention components consist of education, behavioral modification and active learning. The categorical nature of the intervention dosage assignment problem dictates the need for hybrid model predictive control (HMPC) schemes, ultimately leading to improved outcomes. The goal is to design a controller that generates an intervention dosage sequence which improves a participant's healthy eating behavior and physical activity to better control GWG. An improved formulation of self-regulation is also presented through the use of Internal Model Control (IMC), allowing greater flexibility in describing self-regulatory behavior. Simulation results illustrate the basic workings of the model and demonstrate the benefits of hybrid predictive control for optimized GWG adaptive interventions.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":" ","pages":"1970-1975"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/acc.2013.6580124","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31953706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1109/ACC.2013.6580546
Brandon Lindley, Luis Mier-Y-Teran-Romero, Ira B Schwartz
We study the effects of noise on the dynamics of a system of coupled self-propelling particles in the case where the coupling is time-delayed, and the delays are discrete and randomly generated. Previous work has demonstrated that the stability of a class of emerging patterns depends upon all moments of the time delay distribution, and predicts their bifurcation parameter ranges. Near the bifurcations of these patterns, noise may induce a transition from one type of pattern to another. We study the onset of these noise-induced swarm re-organizations by numerically simulating the system over a range of noise intensities and for various distributions of the delays. Interestingly, there is a critical noise threshold above which the system is forced to transition from a less organized state to a more organized one. We explore this phenomenon by quantifying this critical noise threshold, and note that transition time between states varies as a function of both the noise intensity and delay distribution.
{"title":"Noise Induced Pattern Switching in Randomly Distributed Delayed Swarms.","authors":"Brandon Lindley, Luis Mier-Y-Teran-Romero, Ira B Schwartz","doi":"10.1109/ACC.2013.6580546","DOIUrl":"https://doi.org/10.1109/ACC.2013.6580546","url":null,"abstract":"<p><p>We study the effects of noise on the dynamics of a system of coupled self-propelling particles in the case where the coupling is time-delayed, and the delays are discrete and randomly generated. Previous work has demonstrated that the stability of a class of emerging patterns depends upon all moments of the time delay distribution, and predicts their bifurcation parameter ranges. Near the bifurcations of these patterns, noise may induce a transition from one type of pattern to another. We study the onset of these noise-induced swarm re-organizations by numerically simulating the system over a range of noise intensities and for various distributions of the delays. Interestingly, there is a critical noise threshold above which the system is forced to transition from a less organized state to a more organized one. We explore this phenomenon by quantifying this critical noise threshold, and note that transition time between states varies as a function of both the noise intensity and delay distribution.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2013 ","pages":"4587-4591"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ACC.2013.6580546","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32800518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1109/ACC.2013.6580597
Qing-nan He, Yanxia Shen, Ling-yan Ji, Z. Ji
{"title":"Fault-tolerant control strategy of nonlinear system based on state feedback","authors":"Qing-nan He, Yanxia Shen, Ling-yan Ji, Z. Ji","doi":"10.1109/ACC.2013.6580597","DOIUrl":"https://doi.org/10.1109/ACC.2013.6580597","url":null,"abstract":"","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"25 1","pages":"4897-4902"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84689335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1109/acc.2013.6580439
Sunil Deshpande, Daniel E Rivera
Data-centric estimation methods such as Model-on-Demand and Direct Weight Optimization form attractive techniques for estimating unknown functions from noisy data. These methods rely on generating a local function approximation from a database of regressors at the current operating point with the process repeated at each new operating point. This paper examines the design of optimal input signals formulated to produce informative data to be used by local modeling procedures. The proposed method specifically addresses the distribution of the regressor vectors. The design is examined for a linear time-invariant system under amplitude constraints on the input. The resulting optimization problem is solved using semidefinite relaxation methods. Numerical examples show the benefits in comparison to a classical PRBS input design.
{"title":"Optimal Input Signal Design for Data-Centric Estimation Methods.","authors":"Sunil Deshpande, Daniel E Rivera","doi":"10.1109/acc.2013.6580439","DOIUrl":"https://doi.org/10.1109/acc.2013.6580439","url":null,"abstract":"<p><p>Data-centric estimation methods such as Model-on-Demand and Direct Weight Optimization form attractive techniques for estimating unknown functions from noisy data. These methods rely on generating a local function approximation from a database of regressors at the current operating point with the process repeated at each new operating point. This paper examines the design of optimal input signals formulated to produce informative data to be used by local modeling procedures. The proposed method specifically addresses the distribution of the regressor vectors. The design is examined for a linear time-invariant system under amplitude constraints on the input. The resulting optimization problem is solved using semidefinite relaxation methods. Numerical examples show the benefits in comparison to a classical PRBS input design.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":" ","pages":"3924-3929"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/acc.2013.6580439","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31937010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1109/acc.2013.6580794
Guodong Shi, K. Johansson
{"title":"Convergence of distributed averaging and maximizing algorithms part I: Time-dependent graphs","authors":"Guodong Shi, K. Johansson","doi":"10.1109/acc.2013.6580794","DOIUrl":"https://doi.org/10.1109/acc.2013.6580794","url":null,"abstract":"","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"1 1","pages":"6096-6101"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82498310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1109/acc.2013.6580123
Kevin P Timms, Daniel E Rivera, Linda M Collins, Megan E Piper
Cigarette smoking remains a major public health issue. Despite a variety of treatment options, existing intervention protocols intended to support attempts to quit smoking have low success rates. An emerging treatment framework, referred to as adaptive interventions in behavioral health, addresses the chronic, relapsing nature of behavioral health disorders by tailoring the composition and dosage of intervention components to an individual's changing needs over time. An important component of a rapid and effective adaptive smoking intervention is an understanding of the behavior change relationships that govern smoking behavior and an understanding of intervention components' dynamic effects on these behavioral relationships. As traditional behavior models are static in nature, they cannot act as an effective basis for adaptive intervention design. In this article, behavioral data collected daily in a smoking cessation clinical trial is used in development of a dynamical systems model that describes smoking behavior change during cessation as a self-regulatory process. Drawing from control engineering principles, empirical models of smoking behavior are constructed to reflect this behavioral mechanism and help elucidate the case for a control-oriented approach to smoking intervention design.
{"title":"Control Systems Engineering for Understanding and Optimizing Smoking Cessation Interventions.","authors":"Kevin P Timms, Daniel E Rivera, Linda M Collins, Megan E Piper","doi":"10.1109/acc.2013.6580123","DOIUrl":"https://doi.org/10.1109/acc.2013.6580123","url":null,"abstract":"<p><p>Cigarette smoking remains a major public health issue. Despite a variety of treatment options, existing intervention protocols intended to support attempts to quit smoking have low success rates. An emerging treatment framework, referred to as adaptive interventions in behavioral health, addresses the chronic, relapsing nature of behavioral health disorders by tailoring the composition and dosage of intervention components to an individual's changing needs over time. An important component of a rapid and effective adaptive smoking intervention is an understanding of the behavior change relationships that govern smoking behavior and an understanding of intervention components' dynamic effects on these behavioral relationships. As traditional behavior models are static in nature, they cannot act as an effective basis for adaptive intervention design. In this article, behavioral data collected daily in a smoking cessation clinical trial is used in development of a dynamical systems model that describes smoking behavior change during cessation as a self-regulatory process. Drawing from control engineering principles, empirical models of smoking behavior are constructed to reflect this behavioral mechanism and help elucidate the case for a control-oriented approach to smoking intervention design.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":" ","pages":"1964-1969"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/acc.2013.6580123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31976174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-06-27DOI: 10.1109/ACC.2012.6314926
Peng Guan, M. Raginsky, R. Willett
We consider an online (real-time) control problem that involves an agent performing a discrete-time random walk over a finite state space. The agent's action at each time step is to specify the probability distribution for the next state given the current state. Following the set-up of Todorov (2007, 2009), the state-action cost at each time step is a sum of a nonnegative state cost and a control cost given by the Kullback-Leibler divergence between the agent's next-state distribution and that determined by some fixed passive dynamics. The online aspect of the problem is due to the fact that the state cost functions are generated by a dynamic environment, and the agent learns the current state cost only after having selected the corresponding action. We give an explicit construction of an efficient strategy that has small regret (i.e., the difference between the total state-action cost incurred causally and the smallest cost attainable using noncausal knowledge of the state costs) under mild regularity conditions on the passive dynamics. We demonstrate the performance of our proposed strategy on a simulated target tracking problem.
{"title":"Online Markov decision processes with Kullback-Leibler control cost","authors":"Peng Guan, M. Raginsky, R. Willett","doi":"10.1109/ACC.2012.6314926","DOIUrl":"https://doi.org/10.1109/ACC.2012.6314926","url":null,"abstract":"We consider an online (real-time) control problem that involves an agent performing a discrete-time random walk over a finite state space. The agent's action at each time step is to specify the probability distribution for the next state given the current state. Following the set-up of Todorov (2007, 2009), the state-action cost at each time step is a sum of a nonnegative state cost and a control cost given by the Kullback-Leibler divergence between the agent's next-state distribution and that determined by some fixed passive dynamics. The online aspect of the problem is due to the fact that the state cost functions are generated by a dynamic environment, and the agent learns the current state cost only after having selected the corresponding action. We give an explicit construction of an efficient strategy that has small regret (i.e., the difference between the total state-action cost incurred causally and the smallest cost attainable using noncausal knowledge of the state costs) under mild regularity conditions on the passive dynamics. We demonstrate the performance of our proposed strategy on a simulated target tracking problem.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2 1","pages":"1388-1393"},"PeriodicalIF":0.0,"publicationDate":"2012-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75121025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-06-27DOI: 10.1109/ACC.2012.6315391
C. P. Guillén-Flores, B. Castillo-Toledo, J. P. García-Sandoval, V. González-Álvarez
This paper proposes the design of a fuzzy observer which uses both discrete and continuous measurements and updates the initial condition of the state of the system at each sampling instant to ensure the convergence of the estimation error. The proposed fuzzy observer is tested to estimate the substrate and biomass concentration of an anaerobic wastewater treatment process. The observer performance is compared via numerical simulation with two fuzzy observers which use only continuous measurements, showing a faster convergence rate. Finally, the whole estimation scheme is validated using experimental data from an anaerobic digestion process.
{"title":"On fuzzy observer for systems with both continuous and discrete measurements","authors":"C. P. Guillén-Flores, B. Castillo-Toledo, J. P. García-Sandoval, V. González-Álvarez","doi":"10.1109/ACC.2012.6315391","DOIUrl":"https://doi.org/10.1109/ACC.2012.6315391","url":null,"abstract":"This paper proposes the design of a fuzzy observer which uses both discrete and continuous measurements and updates the initial condition of the state of the system at each sampling instant to ensure the convergence of the estimation error. The proposed fuzzy observer is tested to estimate the substrate and biomass concentration of an anaerobic wastewater treatment process. The observer performance is compared via numerical simulation with two fuzzy observers which use only continuous measurements, showing a faster convergence rate. Finally, the whole estimation scheme is validated using experimental data from an anaerobic digestion process.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"38 1","pages":"5610-5615"},"PeriodicalIF":0.0,"publicationDate":"2012-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85042231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}