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Identification of Affine Linear Parameter Varying Models for Adaptive Interventions in Fibromyalgia Treatment. 纤维肌痛自适应干预的仿射线性参数变化模型的识别。
Pub Date : 2013-12-31 DOI: 10.1109/acc.2013.6580125
P Lopes Dos Santos, Sunil Deshpande, Daniel E Rivera, T-P Azevedo-Perdicoúlis, J A Ramos, Jarred Younger

There is good evidence that naltrexone, an opioid antagonist, has a strong neuroprotective role and may be a potential drug for the treatment of fibromyalgia. In previous work, some of the authors used experimental clinical data to identify input-output linear time invariant models that were used to extract useful information about the effect of this drug on fibromyalgia symptoms. Additional factors such as anxiety, stress, mood, and headache, were considered as additive disturbances. However, it seems reasonable to think that these factors do not affect the drug actuation, but only the way in which a participant perceives how the drug actuates on herself. Under this hypothesis the linear time invariant models can be replaced by State-Space Affine Linear Parameter Varying models where the disturbances are seen as a scheduling signal signal only acting at the parameters of the output equation. In this paper a new algorithm for identifying such a model is proposed. This algorithm minimizes a quadratic criterion of the output error. Since the output error is a linear function of some parameters, the Affine Linear Parameter Varying system identification is formulated as a separable nonlinear least squares problem. Likewise other identification algorithms using gradient optimization methods several parameter derivatives are dynamical systems that must be simulated. In order to increase time efficiency a canonical parametrization that minimizes the number of systems to be simulated is chosen. The effectiveness of the algorithm is assessed in a case study where an Affine Parameter Varying Model is identified from the experimental data used in the previous study and compared with the time-invariant model.

有充分的证据表明,纳曲酮是一种阿片拮抗剂,具有很强的神经保护作用,可能是治疗纤维肌痛的潜在药物。在之前的工作中,一些作者使用实验临床数据来确定输入-输出线性时不变模型,该模型用于提取有关该药物对纤维肌痛症状影响的有用信息。其他因素如焦虑、压力、情绪和头痛被认为是累加性干扰。然而,似乎有理由认为这些因素并不影响药物的作用,而只是影响参与者感知药物如何作用于自己的方式。在此假设下,线性时不变模型可以被状态空间仿射线性参数变化模型所取代,其中扰动被视为仅作用于输出方程参数的调度信号。本文提出了一种新的模型识别算法。该算法使输出误差的二次判据最小化。由于输出误差是某些参数的线性函数,因此将仿射线性变参数系统辨识表述为可分离的非线性最小二乘问题。同样,其他使用梯度优化方法的辨识算法——几个参数导数是必须模拟的动态系统。为了提高时间效率,选择了一种能使待模拟系统数量最少的典型参数化方法。在一个案例研究中评估了算法的有效性,该案例研究从先前研究中使用的实验数据中识别出仿射参数变化模型,并将其与时不变模型进行了比较。
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引用次数: 3
An Extended Kalman Filter to Estimate Human Gait Parameters and Walking Distance. 用扩展卡尔曼滤波器估算人体步态参数和行走距离
Pub Date : 2013-06-01 Epub Date: 2013-08-16 DOI: 10.1109/ACC.2013.6579926
Terrell Bennett, Roozbeh Jafari, Nicholas Gans

In this work, we present a novel method to estimate joint angles and distance traveled by a human while walking. We model the human leg as a two-link revolute robot. Inertial measurement sensors placed on the thigh and shin provide the required measurement inputs. The model and inputs are then used to estimate the desired state parameters associated with forward motion using an extended Kalman filter (EKF). Experimental results with subjects walking in a straight line show that distance walked can be measured with accuracy comparable to a state of the art motion tracking systems. The EKF had an average RMSE of 7 cm over the trials with an average accuracy of greater than 97% for linear displacement.

在这项工作中,我们提出了一种新方法,用于估算人在行走时的关节角度和行走距离。我们将人的腿部建模为双链路旋卷机器人。大腿和小腿上的惯性测量传感器提供所需的测量输入。然后,使用扩展卡尔曼滤波器(EKF),利用模型和输入估计与前行运动相关的理想状态参数。受试者直线行走的实验结果表明,测量行走距离的精确度可与最先进的运动跟踪系统媲美。EKF 在试验中的平均均方根误差为 7 厘米,线性位移的平均准确率超过 97%。
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引用次数: 0
Hybrid Model Predictive Control for Optimizing Gestational Weight Gain Behavioral Interventions. 优化妊娠期体重增加行为干预的混合模型预测控制。
Pub Date : 2013-01-01 DOI: 10.1109/acc.2013.6580124
Yuwen Dong, Daniel E Rivera, Danielle S Downs, Jennifer S Savage, Diana M Thomas, Linda M Collins

Excessive gestational weight gain (GWG) represents a major public health issue. In this paper, we pursue a control engineering approach to the problem by applying model predictive control (MPC) algorithms to act as decision policies in the intervention for assigning optimal intervention dosages. The intervention components consist of education, behavioral modification and active learning. The categorical nature of the intervention dosage assignment problem dictates the need for hybrid model predictive control (HMPC) schemes, ultimately leading to improved outcomes. The goal is to design a controller that generates an intervention dosage sequence which improves a participant's healthy eating behavior and physical activity to better control GWG. An improved formulation of self-regulation is also presented through the use of Internal Model Control (IMC), allowing greater flexibility in describing self-regulatory behavior. Simulation results illustrate the basic workings of the model and demonstrate the benefits of hybrid predictive control for optimized GWG adaptive interventions.

妊娠期体重增加过多(GWG)是一个重大的公共卫生问题。在本文中,我们通过应用模型预测控制(MPC)算法作为干预的决策策略来分配最佳干预剂量,从而采用控制工程方法来解决这个问题。干预包括教育、行为矫正和主动学习。干预剂量分配问题的分类性质决定了需要混合模型预测控制(HMPC)方案,最终导致改善的结果。目标是设计一个控制器,产生干预剂量序列,改善参与者的健康饮食行为和身体活动,以更好地控制GWG。通过使用内部模型控制(IMC),还提出了自我调节的改进公式,允许在描述自我调节行为方面具有更大的灵活性。仿真结果说明了该模型的基本工作原理,并证明了混合预测控制对优化的GWG自适应干预的好处。
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引用次数: 26
Noise Induced Pattern Switching in Randomly Distributed Delayed Swarms. 随机分布延迟蜂群中的噪声诱导模式切换。
Pub Date : 2013-01-01 DOI: 10.1109/ACC.2013.6580546
Brandon Lindley, Luis Mier-Y-Teran-Romero, Ira B Schwartz

We study the effects of noise on the dynamics of a system of coupled self-propelling particles in the case where the coupling is time-delayed, and the delays are discrete and randomly generated. Previous work has demonstrated that the stability of a class of emerging patterns depends upon all moments of the time delay distribution, and predicts their bifurcation parameter ranges. Near the bifurcations of these patterns, noise may induce a transition from one type of pattern to another. We study the onset of these noise-induced swarm re-organizations by numerically simulating the system over a range of noise intensities and for various distributions of the delays. Interestingly, there is a critical noise threshold above which the system is forced to transition from a less organized state to a more organized one. We explore this phenomenon by quantifying this critical noise threshold, and note that transition time between states varies as a function of both the noise intensity and delay distribution.

本文研究了噪声对耦合自推进粒子系统动力学的影响,该系统的耦合是时滞的,且时滞是离散的和随机产生的。以前的工作已经证明了一类新兴模式的稳定性取决于时延分布的所有矩,并预测了它们的分岔参数范围。在这些模式的分岔附近,噪声可能引起从一种模式到另一种模式的转变。我们通过数值模拟系统在一定范围的噪声强度和不同的延迟分布来研究这些噪声诱导的群体重组的开始。有趣的是,存在一个临界噪声阈值,超过该阈值,系统将被迫从组织较少的状态过渡到组织较多的状态。我们通过量化这个临界噪声阈值来探索这一现象,并注意到状态之间的过渡时间作为噪声强度和延迟分布的函数而变化。
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引用次数: 11
Fault-tolerant control strategy of nonlinear system based on state feedback 基于状态反馈的非线性系统容错控制策略
Pub Date : 2013-01-01 DOI: 10.1109/ACC.2013.6580597
Qing-nan He, Yanxia Shen, Ling-yan Ji, Z. Ji
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引用次数: 0
Optimal Input Signal Design for Data-Centric Estimation Methods. 以数据为中心估计方法的最优输入信号设计。
Pub Date : 2013-01-01 DOI: 10.1109/acc.2013.6580439
Sunil Deshpande, Daniel E Rivera

Data-centric estimation methods such as Model-on-Demand and Direct Weight Optimization form attractive techniques for estimating unknown functions from noisy data. These methods rely on generating a local function approximation from a database of regressors at the current operating point with the process repeated at each new operating point. This paper examines the design of optimal input signals formulated to produce informative data to be used by local modeling procedures. The proposed method specifically addresses the distribution of the regressor vectors. The design is examined for a linear time-invariant system under amplitude constraints on the input. The resulting optimization problem is solved using semidefinite relaxation methods. Numerical examples show the benefits in comparison to a classical PRBS input design.

以数据为中心的估计方法,如按需模型和直接权重优化,形成了从噪声数据中估计未知函数的有吸引力的技术。这些方法依赖于从当前工作点的回归量数据库生成局部函数近似值,并在每个新工作点重复该过程。本文探讨了最佳输入信号的设计,以产生供局部建模程序使用的信息数据。提出的方法专门针对回归向量的分布。在输入的振幅约束下,对线性时不变系统的设计进行了检验。采用半定松弛法求解优化问题。数值算例显示了与传统PRBS输入设计相比的优点。
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引用次数: 11
Convergence of distributed averaging and maximizing algorithms part I: Time-dependent graphs 收敛分布平均和最大化算法第一部分:时间相关图
Pub Date : 2013-01-01 DOI: 10.1109/acc.2013.6580794
Guodong Shi, K. Johansson
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引用次数: 3
Control Systems Engineering for Understanding and Optimizing Smoking Cessation Interventions. 理解和优化戒烟干预的控制系统工程。
Pub Date : 2013-01-01 DOI: 10.1109/acc.2013.6580123
Kevin P Timms, Daniel E Rivera, Linda M Collins, Megan E Piper

Cigarette smoking remains a major public health issue. Despite a variety of treatment options, existing intervention protocols intended to support attempts to quit smoking have low success rates. An emerging treatment framework, referred to as adaptive interventions in behavioral health, addresses the chronic, relapsing nature of behavioral health disorders by tailoring the composition and dosage of intervention components to an individual's changing needs over time. An important component of a rapid and effective adaptive smoking intervention is an understanding of the behavior change relationships that govern smoking behavior and an understanding of intervention components' dynamic effects on these behavioral relationships. As traditional behavior models are static in nature, they cannot act as an effective basis for adaptive intervention design. In this article, behavioral data collected daily in a smoking cessation clinical trial is used in development of a dynamical systems model that describes smoking behavior change during cessation as a self-regulatory process. Drawing from control engineering principles, empirical models of smoking behavior are constructed to reflect this behavioral mechanism and help elucidate the case for a control-oriented approach to smoking intervention design.

吸烟仍然是一个主要的公共卫生问题。尽管有多种治疗选择,现有的旨在支持戒烟尝试的干预方案成功率很低。一种被称为行为健康适应性干预的新兴治疗框架,通过调整干预成分的组成和剂量来适应个人随时间变化的需求,解决行为健康障碍的慢性、复发性问题。快速有效的适应性吸烟干预的一个重要组成部分是了解控制吸烟行为的行为改变关系,以及了解干预成分对这些行为关系的动态影响。传统的行为模型本质上是静态的,不能作为自适应干预设计的有效依据。在这篇文章中,在戒烟临床试验中每天收集的行为数据被用于开发一个动态系统模型,该模型将戒烟期间的吸烟行为改变描述为一个自我调节过程。根据控制工程原理,构建吸烟行为的经验模型来反映这种行为机制,并有助于阐明以控制为导向的吸烟干预设计方法。
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引用次数: 20
Online Markov decision processes with Kullback-Leibler control cost 具有Kullback-Leibler控制成本的在线马尔可夫决策过程
Pub Date : 2012-06-27 DOI: 10.1109/ACC.2012.6314926
Peng Guan, M. Raginsky, R. Willett
We consider an online (real-time) control problem that involves an agent performing a discrete-time random walk over a finite state space. The agent's action at each time step is to specify the probability distribution for the next state given the current state. Following the set-up of Todorov (2007, 2009), the state-action cost at each time step is a sum of a nonnegative state cost and a control cost given by the Kullback-Leibler divergence between the agent's next-state distribution and that determined by some fixed passive dynamics. The online aspect of the problem is due to the fact that the state cost functions are generated by a dynamic environment, and the agent learns the current state cost only after having selected the corresponding action. We give an explicit construction of an efficient strategy that has small regret (i.e., the difference between the total state-action cost incurred causally and the smallest cost attainable using noncausal knowledge of the state costs) under mild regularity conditions on the passive dynamics. We demonstrate the performance of our proposed strategy on a simulated target tracking problem.
我们考虑一个在线(实时)控制问题,该问题涉及一个代理在有限状态空间上执行离散时间随机行走。agent在每个时间步的动作是给定当前状态指定下一个状态的概率分布。根据Todorov(2007, 2009)的建立,每个时间步的状态-行动成本是由agent下一状态分布与某些固定被动动态决定的Kullback-Leibler散度给出的非负状态成本和控制成本之和。问题的在线方面是由于状态代价函数是由动态环境生成的,并且代理只有在选择了相应的动作之后才学习当前状态代价。在被动动力学的温和规则条件下,我们给出了一个具有小遗憾的有效策略的明确构造(即,在状态成本的非因果知识下产生的总状态-行动成本与可获得的最小成本之间的差异)。我们在一个模拟目标跟踪问题上验证了所提策略的性能。
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引用次数: 13
On fuzzy observer for systems with both continuous and discrete measurements 连续和离散测量系统的模糊观测器
Pub Date : 2012-06-27 DOI: 10.1109/ACC.2012.6315391
C. P. Guillén-Flores, B. Castillo-Toledo, J. P. García-Sandoval, V. González-Álvarez
This paper proposes the design of a fuzzy observer which uses both discrete and continuous measurements and updates the initial condition of the state of the system at each sampling instant to ensure the convergence of the estimation error. The proposed fuzzy observer is tested to estimate the substrate and biomass concentration of an anaerobic wastewater treatment process. The observer performance is compared via numerical simulation with two fuzzy observers which use only continuous measurements, showing a faster convergence rate. Finally, the whole estimation scheme is validated using experimental data from an anaerobic digestion process.
本文提出了一种模糊观测器的设计,该观测器同时使用离散和连续测量,并在每个采样时刻更新系统状态的初始条件,以保证估计误差的收敛性。对所提出的模糊观测器进行了试验,以估计厌氧废水处理过程中的基质和生物质浓度。通过数值模拟比较了两种只使用连续测量值的模糊观测器的性能,显示出更快的收敛速度。最后,利用厌氧消化过程的实验数据对整个估算方案进行了验证。
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引用次数: 0
期刊
Proceedings of the ... American Control Conference. American Control Conference
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