Pub Date : 2012-01-01DOI: 10.1109/ACC.2012.6315693
Liliana Mabel Peinado Cortes, Ryan Zurakowski
The treatment of HIV is complicated by the evolution of antiviral drug resistant virus and the limited availability of antigenically independent antiviral regimens. The consequences to the patient of successive virological failures is such that many strategies to minimize the occurrence of such failures are being investigated. In this paper, a Markov chain-based model of virological failure is introduced. This model considers sequential failure events, and differentiates between several modes of virological failure. This model is then used to evaluate the resistance- targeted interventions by means of testing the impact of a viral load preconditioning strategy on total treatment regimen longevity in HIV patients. It is shown that a proposed intervention targeting pre-existing resistance has the potential to increase the expected time to three sequential virological failures by an average of 3.3 years per patient. When combined with an intervention targeting patient compliance, the total potential increase in the time to three sequential virological failures is as high as 11.2 years. The impact on patient and public health is discussed.
{"title":"Resistance evolution in HIV - modeling when to intervene.","authors":"Liliana Mabel Peinado Cortes, Ryan Zurakowski","doi":"10.1109/ACC.2012.6315693","DOIUrl":"https://doi.org/10.1109/ACC.2012.6315693","url":null,"abstract":"<p><p>The treatment of HIV is complicated by the evolution of antiviral drug resistant virus and the limited availability of antigenically independent antiviral regimens. The consequences to the patient of successive virological failures is such that many strategies to minimize the occurrence of such failures are being investigated. In this paper, a Markov chain-based model of virological failure is introduced. This model considers sequential failure events, and differentiates between several modes of virological failure. This model is then used to evaluate the resistance- targeted interventions by means of testing the impact of a viral load preconditioning strategy on total treatment regimen longevity in HIV patients. It is shown that a proposed intervention targeting pre-existing resistance has the potential to increase the expected time to three sequential virological failures by an average of 3.3 years per patient. When combined with an intervention targeting patient compliance, the total potential increase in the time to three sequential virological failures is as high as 11.2 years. The impact on patient and public health is discussed.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2012 ","pages":"4053-4058"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ACC.2012.6315693","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32703651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-01-01DOI: 10.1109/acc.2012.6315424
Yuwen Dong, Daniel E Rivera, Diana M Thomas, Jesús E Navarro-Barrientos, Danielle S Downs, Jennifer S Savage, Linda M Collins
Excessive gestational weight gain (GWG) represents a major public health concern. In this paper, we present a dynamical systems model that describes how a behavioral intervention can influence weight gain during pregnancy. The model relies on the integration of a mechanistic energy balance with a dynamical behavioral model. The behavioral model incorporates some well-accepted concepts from psychology: the Theory of Planned Behavior (TPB) and the principle of self-regulation which describes how internal processes within the individual can serve to reinforce the positive outcomes of an intervention. A hypothetical case study is presented to illustrate the basic workings of the model and demonstrate how the proper design of the intervention can counteract natural trends towards declines in healthy eating and reduced physical activity during the course of pregnancy. The model can be used by behavioral scientists to evaluate decision rules for adaptive time-varying behavioral interventions, or as the open-loop model for hybrid model predictive control algorithms acting as decision frameworks for such interventions.
{"title":"A Dynamical Systems Model for Improving Gestational Weight Gain Behavioral Interventions.","authors":"Yuwen Dong, Daniel E Rivera, Diana M Thomas, Jesús E Navarro-Barrientos, Danielle S Downs, Jennifer S Savage, Linda M Collins","doi":"10.1109/acc.2012.6315424","DOIUrl":"https://doi.org/10.1109/acc.2012.6315424","url":null,"abstract":"<p><p>Excessive gestational weight gain (GWG) represents a major public health concern. In this paper, we present a dynamical systems model that describes how a behavioral intervention can influence weight gain during pregnancy. The model relies on the integration of a mechanistic energy balance with a dynamical behavioral model. The behavioral model incorporates some well-accepted concepts from psychology: the Theory of Planned Behavior (TPB) and the principle of self-regulation which describes how internal processes within the individual can serve to reinforce the positive outcomes of an intervention. A hypothetical case study is presented to illustrate the basic workings of the model and demonstrate how the proper design of the intervention can counteract natural trends towards declines in healthy eating and reduced physical activity during the course of pregnancy. The model can be used by behavioral scientists to evaluate decision rules for adaptive time-varying behavioral interventions, or as the open-loop model for hybrid model predictive control algorithms acting as decision frameworks for such interventions.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":" ","pages":"4059-4064"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/acc.2012.6315424","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31929962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-01-01DOI: 10.1109/ACC.2012.6314633
Xu Wang, A. Saberi, H. F. Grip, A. Stoorvogel
{"title":"Control of linear systems with input saturation and non-input-additive sustained disturbances - Continuous-time systems","authors":"Xu Wang, A. Saberi, H. F. Grip, A. Stoorvogel","doi":"10.1109/ACC.2012.6314633","DOIUrl":"https://doi.org/10.1109/ACC.2012.6314633","url":null,"abstract":"","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"1 1","pages":"2313-2318"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86015834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-08-18DOI: 10.1109/ACC.2011.5991231
U. Jönsson
Primal and dual stability criteria are derived for systems with uncertain or time-varying components that can be characterized using mixed multipliers. The constant part of the multiplier is used to model time-varying components while the frequency varying multiplier is used to model linear time-invariant uncertainties. It is shown that the dual criterion sometimes reduces to easy-to-use criteria that reveal the structure of the problem.
{"title":"Primal and dual stability criteria for systems with time-varying gains","authors":"U. Jönsson","doi":"10.1109/ACC.2011.5991231","DOIUrl":"https://doi.org/10.1109/ACC.2011.5991231","url":null,"abstract":"Primal and dual stability criteria are derived for systems with uncertain or time-varying components that can be characterized using mixed multipliers. The constant part of the multiplier is used to model time-varying components while the frequency varying multiplier is used to model linear time-invariant uncertainties. It is shown that the dual criterion sometimes reduces to easy-to-use criteria that reveal the structure of the problem.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"35 1","pages":"4354-4360"},"PeriodicalIF":0.0,"publicationDate":"2011-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78067605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-08-18DOI: 10.1109/ACC.2011.5991063
Ö. Morgül
We consider a flexible robot arm modeled as a rigid hub which rotates in an inertial space; a light flexible link is clamped to the rigid body at one end and is free at the other. We assume that the flexible link performs only planar motion. We assume that the strain of the flexible link at the clamped end is measurable. We show that suitable control torques applied to the rigid hub stabilizes the system and achieves orientation under certain conditions. The proposed torque contains derivative, proportional and integral terms of the strain. The stability proofs depend on the passivity of the controller transfer function.
{"title":"On the strain feedback control of a flexible robot arm","authors":"Ö. Morgül","doi":"10.1109/ACC.2011.5991063","DOIUrl":"https://doi.org/10.1109/ACC.2011.5991063","url":null,"abstract":"We consider a flexible robot arm modeled as a rigid hub which rotates in an inertial space; a light flexible link is clamped to the rigid body at one end and is free at the other. We assume that the flexible link performs only planar motion. We assume that the strain of the flexible link at the clamped end is measurable. We show that suitable control torques applied to the rigid hub stabilizes the system and achieves orientation under certain conditions. The proposed torque contains derivative, proportional and integral terms of the strain. The stability proofs depend on the passivity of the controller transfer function.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"3 1","pages":"1795-1800"},"PeriodicalIF":0.0,"publicationDate":"2011-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77403311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-08-18DOI: 10.1109/ACC.2011.5991260
Xiaosong Hu, Fengchun Sun, Y. Zou, H. Peng
A battery model that is suitable for real-time State-of-Charge (SOC) estimation of a Lithium-Ion battery is presented in this paper. The battery open circuit voltage (OCV) as a function of SOC is described by an adaptation of the Nernst equation. The analytical representation can facilitate Kalman filtering or observer-based SOC estimation methods. A zero-state hysteresis correction term is used to depict the hysteresis effect of the battery. A parallel resistance-capacitance (RC) network is used to depict the relaxation effect of the battery. A linear discrete-time formulation of the battery model is derived. A recursive least squares algorithm with forgetting is applied to implement the online parameter calibration. Validation results show that the calibrated model can accurately simulate the dynamic voltage behavior of the Lithium-Ion battery for two different experimental data sets.
{"title":"Online estimation of an electric vehicle Lithium-Ion battery using recursive least squares with forgetting","authors":"Xiaosong Hu, Fengchun Sun, Y. Zou, H. Peng","doi":"10.1109/ACC.2011.5991260","DOIUrl":"https://doi.org/10.1109/ACC.2011.5991260","url":null,"abstract":"A battery model that is suitable for real-time State-of-Charge (SOC) estimation of a Lithium-Ion battery is presented in this paper. The battery open circuit voltage (OCV) as a function of SOC is described by an adaptation of the Nernst equation. The analytical representation can facilitate Kalman filtering or observer-based SOC estimation methods. A zero-state hysteresis correction term is used to depict the hysteresis effect of the battery. A parallel resistance-capacitance (RC) network is used to depict the relaxation effect of the battery. A linear discrete-time formulation of the battery model is derived. A recursive least squares algorithm with forgetting is applied to implement the online parameter calibration. Validation results show that the calibrated model can accurately simulate the dynamic voltage behavior of the Lithium-Ion battery for two different experimental data sets.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"49 1","pages":"935-940"},"PeriodicalIF":0.0,"publicationDate":"2011-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81939630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-08-18DOI: 10.1109/ACC.2011.5990643
J. Mohammadpour, M. Franchek, K. Grigoriadis
Faults affecting the automotive engines can potentially lead to increased emissions, increased fuel consumption or engine damage. These negative impacts may be prevented, or at least alleviated, if faults can be detected and isolated in a timely manner. The US Federal and State regulations dictate that automotive engines operate with an On-Board Diagnosis (OBD) system to enable the detection of faults resulting in increased emissions. In this paper, we survey and discuss the different aspects of fault detection and diagnosis in automotive engine systems. The paper aims to describe some of the efforts made in the academia and industry on the fault detection and isolation for a variety of component faults, actuator faults, and sensor faults in automotive engines using various data-driven and model-based methods.
{"title":"A survey on diagnostics methods for automotive engines","authors":"J. Mohammadpour, M. Franchek, K. Grigoriadis","doi":"10.1109/ACC.2011.5990643","DOIUrl":"https://doi.org/10.1109/ACC.2011.5990643","url":null,"abstract":"Faults affecting the automotive engines can potentially lead to increased emissions, increased fuel consumption or engine damage. These negative impacts may be prevented, or at least alleviated, if faults can be detected and isolated in a timely manner. The US Federal and State regulations dictate that automotive engines operate with an On-Board Diagnosis (OBD) system to enable the detection of faults resulting in increased emissions. In this paper, we survey and discuss the different aspects of fault detection and diagnosis in automotive engine systems. The paper aims to describe some of the efforts made in the academia and industry on the fault detection and isolation for a variety of component faults, actuator faults, and sensor faults in automotive engines using various data-driven and model-based methods.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"23 1","pages":"985-990"},"PeriodicalIF":0.0,"publicationDate":"2011-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90967851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-07-22DOI: 10.1007/978-3-642-22720-2_58
R. Karthi, C. Rajendran, K. Rameshkumar
{"title":"Neighborhood Search Assisted Particle Swarm Optimization (NPSO) Algorithm for Partitional Data Clustering Problems","authors":"R. Karthi, C. Rajendran, K. Rameshkumar","doi":"10.1007/978-3-642-22720-2_58","DOIUrl":"https://doi.org/10.1007/978-3-642-22720-2_58","url":null,"abstract":"","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"1 1","pages":"552-561"},"PeriodicalIF":0.0,"publicationDate":"2011-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75175703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-07-22DOI: 10.1007/978-3-642-22709-7_48
Sudharsan Sundararajan, H. Narayanan, V. Pavithran, K. Voruganti, K. Achuthan
{"title":"Preventing Insider Attacks in the Cloud","authors":"Sudharsan Sundararajan, H. Narayanan, V. Pavithran, K. Voruganti, K. Achuthan","doi":"10.1007/978-3-642-22709-7_48","DOIUrl":"https://doi.org/10.1007/978-3-642-22709-7_48","url":null,"abstract":"","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"18 1","pages":"488-500"},"PeriodicalIF":0.0,"publicationDate":"2011-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75429026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-07-22DOI: 10.1007/978-3-642-22726-4_4
Meenal A. Borkar, Nitin
{"title":"3D-CGIN: A 3 Disjoint Paths CGIN with Alternate Source","authors":"Meenal A. Borkar, Nitin","doi":"10.1007/978-3-642-22726-4_4","DOIUrl":"https://doi.org/10.1007/978-3-642-22726-4_4","url":null,"abstract":"","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"20 1","pages":"25-36"},"PeriodicalIF":0.0,"publicationDate":"2011-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74598942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}