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Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics最新文献

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Design of a Teleoperated Needle Steering System for MRI-guided Prostate Interventions. 设计用于核磁共振成像引导下前列腺介入治疗的远程操作针引导系统。
Reza Seifabadi, Iulian Iordachita, Gabor Fichtinger

Accurate needle placement plays a key role in success of prostate biopsy and brachytherapy. During percutaneous interventions, the prostate gland rotates and deforms which may cause significant target displacement. In these cases straight needle trajectory is not sufficient for precise targeting. Although needle spinning and fast insertion may be helpful, they do not entirely resolve the issue. We propose robot-assisted bevel-tip needle steering under MRI guidance as a potential solution to compensate for the target displacement. MRI is chosen for its superior soft tissue contrast in prostate imaging. Due to the confined workspace of the MRI scanner and the requirement for the clinician to be present inside the MRI room during the procedure, we designed a MRI-compatible 2-DOF haptic device to command the needle steering slave robot which operates inside the scanner. The needle steering slave robot was designed to be integrated with a previously developed pneumatically actuated transperineal robot for MRI-guided prostate needle placement. We describe design challenges and present the conceptual design of the master and slave robots and the associated controller.

前列腺活检和近距离放射治疗的成功与否,关键在于准确的穿刺针置放位置。在经皮介入过程中,前列腺会发生旋转和变形,这可能会导致目标发生明显的位移。在这种情况下,笔直的针头轨迹不足以实现精确定位。虽然针头旋转和快速插入可能会有所帮助,但并不能完全解决问题。我们建议在核磁共振成像引导下使用机器人辅助锥尖针头转向,作为补偿靶点位移的潜在解决方案。选择核磁共振成像是因为它在前列腺成像中具有卓越的软组织对比度。由于核磁共振成像扫描仪的工作空间有限,而且在手术过程中临床医生必须在核磁共振成像室内,因此我们设计了一种与核磁共振成像兼容的 2-DOF 触觉装置,用于指挥在扫描仪内工作的针头转向从属机器人。穿刺针转向从属机器人的设计目的是与之前开发的用于核磁共振成像引导下前列腺穿刺针置入的气动驱动经会阴机器人集成。我们描述了设计挑战,并介绍了主从机器人及相关控制器的概念设计。
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引用次数: 0
Comparing Two Computational Mechanisms for Explaining Functional Recovery in Robot-Therapy of Stroke Survivors. 比较两种解释脑卒中幸存者机器人治疗中功能恢复的计算机制。
Davide Piovesan, Maura Casadio, Ferdinando A Mussa-Ivaldi, Pietro Morasso

In this paper we discuss two possible strategies of movement control that can be used by stroke survivors during rehabilitation robotics training. To perform a reaching task in a minimally assistive force field, subjects either can move following the trajectory provided by the assistive force or they can use an internal representation of a minimum jerk trajectory from their starting position to the target. We used the stiffness and damping values directly estimated from the experimental data to simulate the trajectories that result by taking into account both hypotheses. The comparison of the simulated results with the data collected on four hemiparetic subjects supports the hypothesis that the central nervous system (CNS) is still able to correctly plan the movement, although a normal execution is impaired.

在本文中,我们讨论了两种可能的运动控制策略,可以用于康复机器人训练中风幸存者。为了在最小辅助力场中完成伸手任务,受试者可以按照辅助力提供的轨迹移动,也可以使用从起始位置到目标的最小跳动轨迹的内部表示。我们使用从实验数据中直接估计的刚度和阻尼值来模拟考虑这两种假设而产生的轨迹。将模拟结果与四名偏瘫受试者的数据进行比较,支持了中枢神经系统(CNS)仍然能够正确规划运动的假设,尽管正常的执行能力受到损害。
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引用次数: 13
Sensor-based technology in the study of motor skills in infants at risk for ASD. 基于传感器的技术在ASD风险婴儿运动技能研究中的应用。
Fabrizio Taffoni, Valentina Focaroli, Domenico Formica, Eugenio Gugliemelli, Flavio Keller, Jana M Iverson

Motor impairments seems to play an important role in neurodevelopmental disorders such as autism spectrum disorders (ASD). Early detection of motor abnormalities during first years of life, may give important information regarding whether a child may receive a later diagnosis of Autism: for this reason an objective assessment of motor performance is crucial. While there are several technological solutions suitable to this end, they often require highly structured environments. In this work we propose the use of a magneto-inertial platform to study early motor performance between 12-36 months of age suitable to be used in non-structured environment.

运动障碍似乎在自闭症谱系障碍(ASD)等神经发育障碍中起着重要作用。在生命最初几年的运动异常的早期检测,可以提供关于儿童是否可能接受自闭症的诊断的重要信息:因此,运动表现的客观评估是至关重要的。虽然有几种技术解决方案适合于此目的,但它们通常需要高度结构化的环境。在这项工作中,我们建议使用磁惯性平台来研究适合在非结构化环境中使用的12-36个月大的早期运动性能。
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引用次数: 31
Preliminary Evaluation of a MRI-compatible Modular Robotic System for MRI-guided Prostate Interventions. 用于mri引导前列腺干预的mri兼容模块化机器人系统的初步评估。
Sang-Eun Song, Nathan Cho, Junichi Tokuda, Nobuhiko Hata, Clare Tempany, Gabor Fichtinger, Iulian Iordachita

Magnetic Resonance Imaging (MRI) guided robotic interventions have been introduced in order to advance prostate cancer detection and treatment. To overcome problems of such robotic interventions, we have been developing a pneumatically actuated MRI-compatible modular robotic system for MRI-guided transperineal prostate intervention and its interventional procedure. For system evaluation, a series of experiments have been conducted and this paper reports a needle insertion experiment using prostate phantom and patient mockup trials. The needle insertion experiment resulted in noticeable consistent error in one direction, which we will investigate further. Nonetheless, patient mockup experiences suggest that the modular robotic system and its interventional procedure are well integrated and implemented in clinical environment.

磁共振成像(MRI)引导的机器人干预已被引入,以推进前列腺癌的检测和治疗。为了克服这种机器人干预的问题,我们一直在开发一种气动驱动的mri兼容模块化机器人系统,用于mri引导的经会阴前列腺干预及其介入程序。为了对系统进行评估,我们进行了一系列的实验,本文报道了一个使用前列腺假体和患者模型的针刺实验。针刺实验在一个方向上产生了明显的一致性误差,我们将进一步研究。尽管如此,患者的模型经验表明,模块化机器人系统及其介入程序可以很好地集成并在临床环境中实施。
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引用次数: 14
New Steady-Hand Eye Robot with Micro-Force Sensing for Vitreoretinal Surgery. 用于玻璃体视网膜手术的新型微力传感稳定手眼机器人。
Ali Uneri, Marcin A Balicki, James Handa, Peter Gehlbach, Russell H Taylor, Iulian Iordachita

In retinal microsurgery, surgeons are required to perform micron scale maneuvers while safely applying forces to the retinal tissue that are below sensory perception. Real-time characterization and precise manipulation of this delicate tissue has thus far been hindered by human limits on tool control and the lack of a surgically compatible endpoint sensing instrument. Here we present the design of a new generation, cooperatively controlled microsurgery robot with a remote center-of-motion (RCM) mechanism and an integrated custom micro-force sensing surgical hook. Utilizing the forces measured by the end effector, we correct for tool deflections and implement a micro-force guided cooperative control algorithm to actively guide the operator. Preliminary experiments have been carried out to test our new control methods on raw chicken egg inner shell membranes and to capture useful dynamic characteristics associated with delicate tissue manipulations.

在视网膜显微手术中,外科医生需要进行微米级的操作,同时安全地对视网膜组织施加低于感官知觉的力。到目前为止,由于人类对工具控制的限制以及缺乏手术兼容的端点传感仪器,对这种脆弱组织的实时表征和精确操作一直受到阻碍。在这里,我们设计了新一代的协作控制显微手术机器人,该机器人具有远程运动中心(RCM)机构和集成的定制微力传感手术钩。利用末端执行器测量的力,校正刀具偏转,并实现微力引导协同控制算法来主动引导操作人员。我们已经进行了初步的实验,以测试我们对生鸡蛋内壳膜的新控制方法,并捕捉与精细组织操作相关的有用动态特性。
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引用次数: 249
Interactive Motion Planning for Steerable Needles in 3D Environments with Obstacles. 具有障碍物的三维环境中可操纵针的交互式运动规划。
Sachin Patil, Ron Alterovitz

Bevel-tip steerable needles for minimally invasive medical procedures can be used to reach clinical targets that are behind sensitive or impenetrable areas and are inaccessible to straight, rigid needles. We present a fast algorithm that can compute motion plans for steerable needles to reach targets in complex, 3D environments with obstacles at interactive rates. The fast computation makes this method suitable for online control of the steerable needle based on 3D imaging feedback and allows physicians to interactively edit the planning environment in real-time by adding obstacle definitions as they are discovered or become relevant. We achieve this fast performance by using a Rapidly Exploring Random Tree (RRT) combined with a reachability-guided sampling heuristic to alleviate the sensitivity of the RRT planner to the choice of the distance metric. We also relax the constraint of constant-curvature needle trajectories by relying on duty-cycling to realize bounded-curvature needle trajectories. These characteristics enable us to achieve orders of magnitude speed-up compared to previous approaches; we compute steerable needle motion plans in under 1 second for challenging environments containing complex, polyhedral obstacles and narrow passages.

用于微创医疗程序的斜尖可操纵针头可用于到达敏感或难以穿透的区域后面的临床目标,并且直的,刚性的针头无法进入。我们提出了一种快速算法,该算法可以计算可操纵针在复杂的3D环境中以交互速率到达目标的运动计划。快速的计算使得该方法适用于基于3D成像反馈的可操纵针的在线控制,并且允许医生通过添加发现或相关的障碍物定义来实时交互式地编辑规划环境。我们通过使用快速探索随机树(RRT)和可达性引导的抽样启发式来减轻RRT规划器对距离度量选择的敏感性,从而实现了这种快速性能。通过利用占空循环来实现有界曲率针轨迹,从而放宽了常曲率针轨迹的约束。与之前的方法相比,这些特性使我们能够实现数量级的加速;在包含复杂多面体障碍物和狭窄通道的挑战性环境中,我们在1秒内计算出可操纵的指针运动计划。
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引用次数: 97
Real-time Gait Mode Intent Recognition of a Powered Knee and Ankle Prosthesis for Standing and Walking. 站立和行走的动力膝关节和踝关节假体的实时步态模式意图识别。
Huseyin Atakan Varol, Frank Sup, Michael Goldfarb

This paper describes a real-time gait mode intent recognition approach for the supervisory control of a powered transfemoral prosthesis. The proposed approach infers user intent by recognizing patterns in the prosthesis sensor's signals in real-time, eliminating the need for sound-side instrumentation and allowing fast mode switching. Simple time based features extracted from frames of prosthesis signals are reduced to lower dimensions. Gaussian Mixture Models are trained using an experimental database for gait mode classification. A voting scheme is applied as a post-processing step to increase the robustness of decision making. The effectiveness of the proposed method is shown via gait experiments on a treadmill with a healthy subject using an able bodied adapter.

本文描述了一种实时步态模式意图识别方法,用于动力股骨假体的监控。该方法通过实时识别假体传感器信号中的模式来推断用户意图,消除了对声音侧仪器的需求,并允许快速模式切换。从假体信号帧中提取简单的基于时间的特征,将其降至较低的维数。利用实验数据库对高斯混合模型进行步态分类训练。为了提高决策的鲁棒性,采用了一种投票方案作为后处理步骤。该方法的有效性通过使用健体适配器与健康受试者在跑步机上进行的步态实验来证明。
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引用次数: 53
Integrated Planning and Image-Guided Control for Planar Needle Steering. 平面针转向的综合规划和图像引导控制。
Kyle B Reed, Vinutha Kallem, Ron Alterovitz, Ken Goldberg, Allison M Okamura, Noah J Cowan

Flexible, tip-steerable needles promise to enhance physicians' abilities to accurately reach targets and maneuver inside the human body while minimizing patient trauma. Here, we present a functional needle steering system that integrates two components: (1) a patient-specific 2D pre- and intra-operative planner that finds an achievable route to a target within a planar slice of tissue (Stochastic Motion Roadmap), and (2) a low-level image-guided feedback controller that keeps the needle tip within that slice. The planner generates a sequence of circular arcs that can be realized by interleaving pure insertions with 180° rotations of the needle shaft. This preplanned sequence is updated in realtime at regular intervals. Concurrently, the low-level image-based controller servos the needle to remain close to the desired plane between plan updates. Both planner and controller are predicated on a previously developed kinematic nonholonomic model of bevel-tip needle steering. We use slighly different needles here that have a small bend near the tip, so we extend the model to account for discontinuities of the tip position caused by 180° rotations. Further, during large rotations of the needle base, we maintain the desired tip angle by compensating for torsional compliance in the needle shaft, neglected in previous needle steering work. By integrating planning, control, and torsion compensation, we demonstrate both accurate targeting and obstacle avoidance.

灵活、针尖可转向的针头有望提高医生准确到达目标和在人体内操作的能力,同时最大限度地减少对病人的创伤。在此,我们介绍一种功能性针头转向系统,该系统集成了两个组件:(1) 病人特定的二维术前和术中计划器,可在组织的平面切片(随机运动路线图)内找到通往目标的可实现路径;(2) 低水平图像引导反馈控制器,可将针尖保持在切片内。规划器生成一连串圆弧,这些圆弧可通过穿插纯插入和针轴 180° 旋转来实现。这个预先计划好的序列会定期进行实时更新。与此同时,基于图像的底层控制器会在计划更新之间伺服织针,使其保持在所需平面附近。计划器和控制器都以之前开发的斜面针尖转向运动学非整体模型为基础。我们在这里使用的针略有不同,针尖附近有一个小弯曲,因此我们扩展了模型,以考虑 180° 旋转造成的针尖位置的不连续性。此外,在针基大幅旋转时,我们通过补偿针轴的扭转顺应性来保持所需的针尖角度,而这在之前的针转向工作中被忽视了。通过整合规划、控制和扭转补偿,我们展示了精确的目标定位和避障功能。
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引用次数: 0
Needle-Tissue Interaction Forces for Bevel-Tip Steerable Needles. 斜尖可操纵针的针-组织相互作用力。
Sarthak Misra, Kyle B Reed, Andrew S Douglas, K T Ramesh, Allison M Okamura

The asymmetry of a bevel-tip needle results in the needle naturally bending when it is inserted into soft tissue. As a first step toward modeling the mechanics of deflection of the needle, we determine the forces at the bevel tip. In order to find the forces acting at the needle tip, we measure rupture toughness and nonlinear material elasticity parameters of several soft tissue simulant gels and chicken tissue. We incorporate these physical parameters into a finite element model that includes both contact and cohesive zone models to simulate tissue cleavage. We investigate the sensitivity of the tip forces to tissue rupture toughness, linear and nonlinear tissue elasticity, and needle tip bevel angle. The model shows that the tip forces are sensitive to the rupture toughness. The results from these studies contribute to a mechanics-based model of bevel-tip needle steering, extending previous work on kinematic models.

斜尖针头的不对称性导致针头在插入软组织时自然弯曲。作为模拟针偏转力学的第一步,我们确定了斜角尖端的力。为了找出作用在针尖处的力,我们测量了几种软组织模拟凝胶和鸡组织的断裂韧性和非线性材料弹性参数。我们将这些物理参数合并到一个有限元模型中,该模型包括接触区和内聚区模型,以模拟组织解理。我们研究了针尖力对组织断裂韧性、线性和非线性组织弹性以及针尖斜角的敏感性。模型表明,尖端力对断裂韧性非常敏感。这些研究的结果有助于建立一个基于力学的斜尖针转向模型,扩展了先前在运动学模型上的工作。
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引用次数: 120
Compensating for Torsion Windup in Steerable Needles. 操纵针扭转绕组的补偿。
Kyle B Reed

Long, flexible, bevel-tip needles curve during insertion into tissue, and rotations of the needle base reorient the tip to steer subsequent insertions. Friction between the tissue and the needle shaft, however, can cause a severe discrepancy between the needle base and tip angles. In this paper, I demonstrate an algorithm to properly align the entire length of the needle using torque measured at the base. My algorithm uses several intermediate base rotations to align the orientation of points along the shaft with the desired angle, with minimal remaining torque exerted by the base. I performed an experimental validation with four angle sensors attached to the needle throughout the tissue. My compensation algorithm decreased the lag throughout the needle by up to 88%.

长而灵活的斜尖针在插入组织时弯曲,针基的旋转使针尖重新定向,以引导后续的插入。然而,组织和针轴之间的摩擦会导致针基部和针尖角度之间的严重差异。在本文中,我演示了一种算法,使用在底座测量的扭矩来正确地对齐针的整个长度。我的算法使用几个中间的基础旋转来对齐沿轴的点的方向与所需的角度,以最小的剩余扭矩施加的基础。我做了一个实验验证用四个角度传感器连接到贯穿组织的针头上。我的补偿算法将整个针头的延迟减少了88%。
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引用次数: 15
期刊
Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics
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