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Associations between Baseline Hyponatremia and Activities of Daily Living and Muscle Health in Convalescent Stroke Patients. 中风康复期患者基线低钠血症与日常生活活动和肌肉健康之间的关系
IF 1.5 Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.2490/prm.20240019
Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Aomi Kuzuhara, Kota Hori, Takenori Hamada, Kouki Yoneda, Kenichiro Maekawa

Objectives: Evidence is scarce regarding the association between hyponatremia and functional outcomes among older hospitalized patients. We aimed to evaluate the associations between baseline hyponatremia and improvement in activities of daily living (ADL) and muscle health in hospitalized post-stroke patients.

Methods: This retrospective cohort study included hospitalized post-stroke patients. Serum sodium concentrations were extracted from medical records based on blood tests performed within 24 h of admission, with hyponatremia defined as a serum sodium concentration below135 mEq/L. Primary outcome was the discharge ADL as assessed by the motor domain of the Functional Independence Measure (FIM-motor) and its corresponding gain during hospitalization. Other outcomes encompassed the discharge scores for skeletal muscle mass (SMI) and handgrip strength (HGS). Multivariate linear regression analyses were used to determine the association between hyponatremia and outcomes of interest, adjusted for potential confounders.

Results: Data from 955 patients (mean age 73.2 years; 53.6% men) were analyzed. The median baseline blood sodium level was 139 [interquartile range: 137, 141] mEq/L, and 84 patients (8.8%) exhibited hyponatremia. After full adjustment for confounders, baseline hyponatremia was significantly and negatively associated with FIM-motor at discharge (β=-0.036, P=0.033) and its gain during hospital stay (β=-0.051, P=0.033). Baseline hyponatremia exhibited an independent and negative association with discharge HGS (β=-0.031, P=0.027), whereas no significant association was found between baseline hyponatremia and discharge SMI (β=-0.015, P=0.244).

Conclusions: Baseline hyponatremia demonstrated a correlation with compromised ADL and muscle health in individuals undergoing rehabilitation after stroke.

目的:有关低钠血症与老年住院患者功能预后之间关系的证据很少。我们旨在评估基线低钠血症与中风后住院患者日常生活活动(ADL)和肌肉健康改善之间的关系:这项回顾性队列研究包括住院的中风后患者。根据入院后 24 小时内的血液检测结果,从病历中提取血清钠浓度,血清钠浓度低于 135 mEq/L 即为低钠血症。主要研究结果是通过功能独立性测量(FIM-motor)运动领域评估的出院 ADL 及其在住院期间的相应增益。其他结果包括骨骼肌质量(SMI)和手握力(HGS)的出院评分。多变量线性回归分析用于确定低钠血症与相关结果之间的关系,并对潜在的混杂因素进行调整:分析了 955 名患者(平均年龄 73.2 岁;53.6% 为男性)的数据。基线血钠水平中位数为 139 [四分位间范围:137,141] mEq/L,84 名患者(8.8%)出现低钠血症。在对混杂因素进行充分调整后,基线低钠血症与出院时的 FIM-运动显著负相关(β=-0.036,P=0.033),与住院期间的增益显著负相关(β=-0.051,P=0.033)。基线低钠血症与出院 HGS 呈独立负相关(β=-0.031,P=0.027),而基线低钠血症与出院 SMI 之间无显著关联(β=-0.015,P=0.244):结论:基线低钠血症与脑卒中后接受康复治疗的患者的 ADL 和肌肉健康受损有关。
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引用次数: 0
Life Goal Domains, Traits, and Setting Process in the Collaboration between Healthcare Professionals and Cancer Survivors: A Scoping Review. 医疗保健专业人员与癌症幸存者合作中的人生目标领域、特质和设定过程:范围综述》。
Pub Date : 2024-05-21 eCollection Date: 2024-01-01 DOI: 10.2490/prm.20240018
Katsuma Ikeuchi, Seiji Nishida, Mari Karikawa

Objectives: : This study aimed to describe the classification of goal domains, goal traits, and the goal-setting process as revealed by previous life goal-setting practices of healthcare professionals collaborating with cancer survivors.

Methods: : The design was a scoping review. The MEDLINE, Academic Search Premier, and CINAHL databases were searched and mapped for papers with descriptions of goal domains, goal traits, and the goal-setting process. Goal domains were classified as life goals that were health-related, psychological, social, achievement-related, and leisure goals. Goal traits were classified based on specific, measurable, achievable, relevant, and timed (SMART) criteria. The goal-setting process was classified based on the frameworks of goal-setting phases (preparation, formulation, follow-up) and their components.

Results: : In total, 229 papers were identified, and 24 papers were included in the final analysis. All papers included health-related goals, followed by psychological and social goals. All goal domains were included in 41.7% of the papers. Relevant goals were the most common and timed goals were the least common. All papers included either of the components that comprise the preparation or formulation phases. We found that 12.5% of papers did not include any of the three components of the follow-up phase.

Conclusions: : The life goals collaboratively set between cancer survivors and healthcare professionals were characterized by the following: psychological and social goal domains, numerous goal domains, more relevant goals and fewer timed goals, low proportion of patient education in the preparation phase, and high proportion of evaluation of progress or achievement in the follow-up phase.

研究目的本研究旨在描述目标领域的分类、目标特征以及医护人员在与癌症幸存者合作制定生活目标的过程中发现的目标制定过程:方法::设计了一个范围综述。我们在 MEDLINE、Academic Search Premier 和 CINAHL 数据库中搜索并映射了有关目标领域、目标特征和目标设定过程的论文。目标领域分为与健康相关的生活目标、心理目标、社会目标、成就目标和休闲目标。目标特征根据具体、可衡量、可实现、相关和有时间限制(SMART)的标准进行分类。目标设定过程根据目标设定阶段(准备、制定、跟进)及其组成部分的框架进行分类:共发现 229 篇论文,其中 24 篇被纳入最终分析。所有论文都包括与健康相关的目标,其次是心理和社会目标。41.7%的论文包含所有目标领域。相关目标最常见,定时目标最不常见。所有论文都包含了准备阶段或制定阶段的任何一个组成部分。我们发现,12.5% 的论文未包含后续阶段三个组成部分中的任何一个:癌症幸存者与医护人员合作制定的生活目标具有以下特点:心理和社会目标领域、目标领域多、相关目标多、定时目标少、准备阶段的患者教育比例低、后续阶段的进展或成就评估比例高。
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引用次数: 0
Effect of One Session of Muscle Blood Flow Restriction Training Versus Normal Training on Blood Lactate Level. 一次肌肉血流限制训练与正常训练对血液乳酸水平的影响
Pub Date : 2024-05-01 eCollection Date: 2024-01-01 DOI: 10.2490/prm.20240017
Hiroji Fukuta

Objectives: Blood flow restriction training (BFRT) is useful for improving muscle strength. However, it involves a long training time and is unsuitable for vigorous exercise. Muscle blood flow restriction training (MBFRT), which uses multiple parallel pneumatic cuffs (MPCs) to compress large areas of the extremities and restrict blood flow, was subsequently developed to address these issues. This study compared the effects of MBFRT with normal training (NT).

Methods: Ten healthy adults underwent low-intensity MBFRT. MPC pressure was increased to 200 mmHg just before training. The exercise was a bodyweight half-squat. Three sets of 30 squats were performed. Two weeks later, the participants underwent NT with the same exercise. Blood lactate levels were measured before the start of training and at 1 and 5 min after training. The Borg index was also measured at the end of the training.

Results: The blood lactate level was elevated at 1 min after MBFRT and NT. The elevated blood lactate level was maintained at 5 min after MBFRT, whereas the lactate level was significantly decreased at 5 min after NT. The Borg index at the end of the training was significantly higher in MBFRT than in NT.

Conclusions: Lactic acid accumulates in the muscles during low-intensity MBFRT, thereby initiating type II fiber activity.

目的:血流限制训练(BFRT)有助于提高肌肉力量。然而,它需要较长的训练时间,不适合剧烈运动。肌肉血流限制训练(MBFRT)使用多个平行气动袖带(MPC)来压迫四肢的大面积区域并限制血流,随后被开发出来以解决这些问题。本研究比较了 MBFRT 与正常训练(NT)的效果:方法:10 名健康成年人接受了低强度 MBFRT。方法:10 名健康成年人接受了低强度 MBFRT,训练前将 MPC 压力提高到 200 mmHg。训练方法是负重半蹲。共进行了三组,每组 30 个深蹲。两周后,参与者进行了同样的 NT 训练。在训练开始前、训练后 1 分钟和 5 分钟测量血液乳酸水平。训练结束时还测量了博格指数:结果:MBFRT 和 NT 训练后 1 分钟,血乳酸水平升高。结果:MBFRT 和 NT 训练后 1 分钟血液乳酸水平升高,MBFRT 训练后 5 分钟血液乳酸水平维持升高,而 NT 训练后 5 分钟血液乳酸水平明显下降。训练结束时,MBFRT 的博格指数明显高于 NT:结论:在低强度 MBFRT 期间,乳酸会在肌肉中积累,从而启动 II 型纤维活动。
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引用次数: 0
Validity of the Functional Classification of the Upper Extremities for Duchenne Muscular Dystrophy 杜兴氏肌肉萎缩症上肢功能分类的有效性
Pub Date : 2024-04-25 DOI: 10.2490/prm.20240016
Yuta Miyazaki, T. Hara, Kazuki Hagiwara, Takuya Nakamura, Akiko Kamimura, Eri Takeshita, Hirofumi Komaki, Katsuhiro Mizuno, Tetsuya Tsuji, Masahiro Abo
ABSTRACT Objectives: Some upper-limb function assessments can evaluate treatments in the non-ambulatory stage of Duchenne muscular dystrophy (DMD). The Functional Classification of the Upper Extremities (FCUE) was developed for DMD in Japan. The FCUE is easier to use than the Performance of Upper Limb (PUL) and is more detailed than the Brooke Upper Extremity Scale. This study aimed to determine the concurrent validity of FCUE with other methods of assessment for DMD. Methods: This retrospective study reviewed the medical records of 39 boys with DMD from the National Center of Neurology and Psychiatry to evaluate the concurrent validity of the FCUE and PUL using non-parametric Spearman rank correlation (ρ). We also determined the concurrent validity of the Brooke Upper Extremity Scale and PUL for comparison. Results: The ρ value between the FCUE and PUL was −0.914 (P<0.001). The FCUE showed robust concurrent validity with the PUL. That correlation between the FCUE and Brooke Upper Extremity Scale gave a ρ value of −0.854 (P<0.001). Conclusions: The FCUE had a higher concurrent validity with the PUL than with the Brooke Upper Extremity Scale. The FCUE is considered a valid assessment tool of upper-limb function in boys with DMD. Selecting the best assessment method depends on the severity of the patient’s condition and a balance between assessment accuracy and evaluation time.
摘要 目的:一些上肢功能评估可以对杜氏肌营养不良症(DMD)非行走阶段的治疗进行评估。上肢功能分类(FCUE)是日本针对 DMD 而开发的。FCUE 比上肢功能量表 (PUL) 更容易使用,比布鲁克上肢功能量表 (Brooke Upper Extremity Scale) 更详细。本研究旨在确定 FCUE 与其他 DMD 评估方法的并发有效性。方法:这项回顾性研究回顾了国家神经病学和精神病学中心的 39 名 DMD 男孩的病历,使用非参数斯皮尔曼秩相关性 (ρ) 评估了 FCUE 和 PUL 的并发有效性。我们还测定了布鲁克上肢量表和 PUL 的并发有效性,以进行比较。结果FCUE和PUL之间的ρ值为-0.914(P<0.001)。FCUE与PUL显示出很强的并发有效性。FCUE与布鲁克上肢量表之间的相关性ρ值为-0.854(P<0.001)。结论与布鲁克上肢量表相比,功能性评定UE与PUL的并发效度更高。FCUE 被认为是评估 DMD 男孩上肢功能的有效工具。选择最佳评估方法取决于患者病情的严重程度以及评估准确性和评估时间之间的平衡。
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引用次数: 0
Evidence and Recommendations for Acute Stroke Rehabilitation from the Japan Stroke Society: Abridged Secondary Publication of the Japanese-language Version 日本卒中协会关于急性卒中康复的证据和建议:日语版节选二次出版
Pub Date : 2024-04-24 DOI: 10.2490/prm.20240015
Wataru Kakuda, Makoto Nakajima, Koichi Oki, Tetsuo Koyama, Naoki Oyama, Masatoshi Koga, Makoto Hayase, Tsuyoshi Ohta, Yasuyuki Iguchi, Shigeru Fujimoto, Tomohiro Omori, Koichi Matsumoto, Yoichiro Hashimoto, Ryo Itabashi, M. Niimi, Hirokazu Ashiga, Fumihiro Tajima, Kuniaki Ogasawara
ABSTRACT Objectives: In Japan, acute stroke rehabilitation has been expanding more steadily than previously with the nationwide establishment of primary stroke centers. However, Japan previously had no established guidelines for the rehabilitation. Consequently, rehabilitation programs and the provision systems for acute stroke varied among the facilities. To equalize and standardize acute stroke rehabilitation in Japan, it is necessary to develop clinical recommendations for rehabilitation. Therefore, the rehabilitation project team of the Japan Stroke Society aimed to develop the first recommendations for acute stroke rehabilitation in Japan. Methods: The recommendations are based on the results of a survey on the current status of acute stroke rehabilitation at primary stroke centers in Japan, which was completed in 2022, and on a literature review conducted by the rehabilitation project team. Results: The recommendations consist of 19 clinical questions regarding the following topics of acute stroke rehabilitation: (1) head elevation and mobilization training, (2) acute complications, (3) training time and frequency for acute stroke rehabilitation, (4) dysphagia in the acute phase, and (5) acute rehabilitation during pandemics of novel and re-emerging infections, particularly novel coronavirus disease 2019 (COVID-19). The team members agreed on all answers for these 19 clinical questions. Conclusions: These recommendations suggest broad principles of rehabilitative intervention in the acute phase of stroke. In the near future, it is expected that the dissemination of these recommendations will result in an increase in the quality of acute stroke rehabilitation in Japan.
摘要 目的:在日本,随着初级卒中中心在全国范围内的建立,急性卒中康复的发展比以前更加稳定。然而,日本以前没有既定的康复指南。因此,各机构的急性脑卒中康复项目和供应系统各不相同。为了实现日本急性脑卒中康复的均等化和标准化,有必要制定康复的临床建议。因此,日本卒中协会康复项目组旨在为日本急性卒中康复制定第一份建议。方法:该建议基于 2022 年完成的一项关于日本初级卒中中心急性卒中康复现状的调查结果,以及康复项目组进行的文献综述。结果:建议包括19个临床问题,涉及急性卒中康复的以下主题:(1)头部抬高和活动训练;(2)急性并发症;(3)急性卒中康复的训练时间和频率;(4)急性期的吞咽困难;(5)新型和再发感染流行期间的急性康复,尤其是新型冠状病毒病2019(COVID-19)。团队成员就这 19 个临床问题的所有答案达成了一致。得出结论:这些建议提出了中风急性期康复干预的广泛原则。预计在不久的将来,这些建议的推广将提高日本急性卒中康复治疗的质量。
{"title":"Evidence and Recommendations for Acute Stroke Rehabilitation from the Japan Stroke Society: Abridged Secondary Publication of the Japanese-language Version","authors":"Wataru Kakuda, Makoto Nakajima, Koichi Oki, Tetsuo Koyama, Naoki Oyama, Masatoshi Koga, Makoto Hayase, Tsuyoshi Ohta, Yasuyuki Iguchi, Shigeru Fujimoto, Tomohiro Omori, Koichi Matsumoto, Yoichiro Hashimoto, Ryo Itabashi, M. Niimi, Hirokazu Ashiga, Fumihiro Tajima, Kuniaki Ogasawara","doi":"10.2490/prm.20240015","DOIUrl":"https://doi.org/10.2490/prm.20240015","url":null,"abstract":"ABSTRACT Objectives: In Japan, acute stroke rehabilitation has been expanding more steadily than previously with the nationwide establishment of primary stroke centers. However, Japan previously had no established guidelines for the rehabilitation. Consequently, rehabilitation programs and the provision systems for acute stroke varied among the facilities. To equalize and standardize acute stroke rehabilitation in Japan, it is necessary to develop clinical recommendations for rehabilitation. Therefore, the rehabilitation project team of the Japan Stroke Society aimed to develop the first recommendations for acute stroke rehabilitation in Japan. Methods: The recommendations are based on the results of a survey on the current status of acute stroke rehabilitation at primary stroke centers in Japan, which was completed in 2022, and on a literature review conducted by the rehabilitation project team. Results: The recommendations consist of 19 clinical questions regarding the following topics of acute stroke rehabilitation: (1) head elevation and mobilization training, (2) acute complications, (3) training time and frequency for acute stroke rehabilitation, (4) dysphagia in the acute phase, and (5) acute rehabilitation during pandemics of novel and re-emerging infections, particularly novel coronavirus disease 2019 (COVID-19). The team members agreed on all answers for these 19 clinical questions. Conclusions: These recommendations suggest broad principles of rehabilitative intervention in the acute phase of stroke. In the near future, it is expected that the dissemination of these recommendations will result in an increase in the quality of acute stroke rehabilitation in Japan.","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"67 51","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140663790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probable Respiratory Sarcopenia Decreases Activities of Daily Living in Older Patients Hospitalized with Respiratory Diseases: A Cross-sectional Study 疑似呼吸道肌肉疏松症会降低因呼吸道疾病住院的老年患者的日常生活能力:横断面研究
Pub Date : 2024-04-13 DOI: 10.2490/prm.20240014
Toshiyuki Moriyama, Mizuki Tokunaga, Ryoko Hori, H. Itoh, Akiko Hachisuka, Mitsuhiro Ochi, Y. Matsushima, Satoru Saeki
ABSTRACT Objectives: Respiratory sarcopenia is characterized by low respiratory muscle mass and respiratory muscle strength, but its impact on activities of daily living (ADL) remains unknown. We aimed to investigate the association between respiratory sarcopenia and decreased ADL. Methods: This retrospective cross-sectional study included older inpatients (≥65 years old) with respiratory diseases who underwent rehabilitation. Because the evaluation of respiratory muscle mass is challenging, probable respiratory sarcopenia was defined according to low appendicular skeletal muscle index (<7 kg/m2 for men, <5.7 kg/m2 for women) and peak expiratory flow rate (<4.4 L/s for men, <3.21 L/s for women). ADL was assessed on the first day of rehabilitation using the baseline Barthel Index (BI). Results: Of 111 inpatients (median age 75 years; 57 women), 13 (11.7%) had probable respiratory sarcopenia. Forty-five patients (40.5%) had sarcopenia and 12 of these had probable respiratory sarcopenia. Pulmonary functions (Forced Vital Capacity and expiratory volume in 1 s) were significantly lower in patients with probable respiratory sarcopenia than those without. Spearman’s rank coefficient analysis showed probable respiratory sarcopenia did not significantly correlate with age, phase angle, Charlson Comorbidity Index (CCI), or hemoglobin (Hb). Multivariate linear regression analysis with baseline BI revealed probable respiratory sarcopenia (β −0.279 and P=0.004) was the significant factor after adjusting for age, sex, body mass index, chronic obstructive pulmonary disease, CCI, and Hb. Conclusions: Probable respiratory sarcopenia was independently associated with decreased ADL in patients aged 65 years and older who were hospitalized with respiratory diseases.
摘要 目的:呼吸肌疏松症的特征是呼吸肌质量和呼吸肌力量较低,但其对日常生活活动(ADL)的影响仍不清楚。我们旨在研究呼吸肌疏松症与 ADL 减少之间的关联。研究方法这项回顾性横断面研究纳入了接受康复治疗的呼吸系统疾病老年住院患者(≥65 岁)。由于呼吸肌质量的评估具有挑战性,因此根据较低的骨骼肌指数(男性小于 7 kg/m2,女性小于 5.7 kg/m2)和呼气峰流速(男性小于 4.4 L/s,女性小于 3.21 L/s)来定义可能的呼吸肌疏松症。在康复治疗的第一天,使用基线巴特尔指数(BI)对ADL进行评估。结果在 111 名住院患者(中位年龄为 75 岁;57 名女性)中,有 13 人(11.7%)可能患有呼吸性肌肉疏松症。45名患者(40.5%)患有肌肉疏松症,其中12名患者可能患有呼吸系统肌肉疏松症。可能患有呼吸道肌肉疏松症的患者的肺功能(1 秒钟内的强制生命容量和呼气量)明显低于未患有呼吸道肌肉疏松症的患者。斯皮尔曼秩系数分析表明,可能的呼吸肌疏松症与年龄、相位角、夏尔森综合症指数(CCI)或血红蛋白(Hb)无明显相关性。在对年龄、性别、体重指数、慢性阻塞性肺病、CCI 和 Hb 进行调整后,基线 BI 的多变量线性回归分析显示,可能的呼吸道肌肉疏松症(β -0.279,P=0.004)是一个重要因素。结论在因呼吸系统疾病住院的 65 岁及以上患者中,可能的呼吸道肌肉疏松症与日常活动能力下降有独立关联。
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引用次数: 0
Does Prehabilitation Reduce Postoperative Length of Hospital Stay after Esophageal Cancer Surgery? 术前康复能否缩短食管癌手术后的住院时间?
Pub Date : 2024-04-10 DOI: 10.2490/prm.20240013
Fumihito Kasai, Takahisa Kobayashi, Eriko Hoshi, T. Nagai, Takeshi Yamashita, K. Otsuka, Masahiko Murakami, Nobuyuki Kawate
ABSTRACT Objectives: At our hospital, prehabilitation has been provided to patients undergoing esophageal cancer surgery since October 2019. This study explored the effects of prehabilitation based on the accumulated database of these patients. Methods: This retrospective cohort study included 621 patients who underwent thoracoscopic subtotal esophagectomy. Multiple linear regression analysis was performed using postoperative hospital stay as the objective variable and age, sex, body mass index (BMI), preoperative ventilatory impairment, left ventricular ejection fraction, preoperative hemoglobin A1c, clinical stage, histological type, operative time, surgical blood loss, postoperative complications, and prehabilitation as explanatory variables. We also performed a multivariate analysis in the subgroup of patients who developed postoperative complications and adjusted for possible confounding factors. Postoperative complications and postoperative hospital stay were compared between patients without (n=416) and with (n=205) prehabilitation. Results: Postoperative complications, age, blood loss, BMI, and ventilatory impairment influenced the overall length of hospital stay. When the analysis was restricted to patients with complications, prehabilitation was added to that list of factors as a substitute for BMI. The rate of postoperative complications was not affected by prehabilitation (P=0.1675). The number of hospital days did not change with or without prehabilitation in the overall population, but when restricted to patients with complications, the number of hospital days was significantly decreased in the prehabilitation group (P=0.0328). Conclusions: Prehabilitation as a perioperative approach has the potential to reduce the postoperative length of hospital stay in patients undergoing esophageal cancer surgery, and active intervention is recommended.
摘要 目的:我院自 2019 年 10 月起为食管癌手术患者提供预康复治疗。本研究根据这些患者积累的数据库,探讨了预康复的效果。研究方法这项回顾性队列研究纳入了 621 名接受胸腔镜食管次全切除术的患者。以术后住院时间为客观变量,年龄、性别、体重指数(BMI)、术前通气功能障碍、左心室射血分数、术前血红蛋白 A1c、临床分期、组织学类型、手术时间、手术失血量、术后并发症和术前康复为解释变量,进行了多元线性回归分析。我们还对出现术后并发症的亚组患者进行了多变量分析,并对可能的混杂因素进行了调整。对未进行术前康复的患者(416 人)和进行术前康复的患者(205 人)的术后并发症和术后住院时间进行了比较。结果如下术后并发症、年龄、失血量、体重指数和通气功能障碍影响了总住院时间。当分析范围仅限于有并发症的患者时,康复前情况被加入到因素列表中,以替代体重指数。术后并发症的发生率不受康复前因素的影响(P=0.1675)。总体住院天数在是否进行康复治疗的情况下没有变化,但如果仅限于有并发症的患者,康复治疗组的住院天数明显减少(P=0.0328)。结论康复前治疗作为一种围手术期方法,有可能缩短食管癌手术患者的术后住院时间,建议积极干预。
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引用次数: 0
Long-term Health-related Quality of Life and Physical Function of COVID-19 Survivors with ICU-acquired Weakness COVID-19 存活者的长期健康相关生活质量和身体功能(ICU 引起的虚弱
Pub Date : 2024-04-03 DOI: 10.2490/prm.20240012
Tomoyo Taketa, Y. Uchiyama, Yohei Miyagi, Seiya Yamakawa, Tetsu Seo, Ai Yanagida, N. Sasanuma, N. Kodama, K. Domen
ABSTRACT Objectives: This study examined the long-term health-related quality of life (HRQOL) and physical function of coronavirus 2019 (COVID-19) survivors diagnosed with intensive care unit-acquired weakness (ICU-AW). The correlation between muscle weakness at ICU discharge and HRQOL was assessed. Methods: A retrospective study was conducted on COVID-19 patients admitted to the ICU at Hyogo Medical University Hospital between January 2021 and November 2021. The HRQOL was evaluated using the SF-36 questionnaire, and physical function, including muscle strength assessed by the Medical Research Council Sum Score (MRC-SS), grip strength, and the 6-min walk distance (6MWD), were assessed 18 months after the onset. ICU-AW was diagnosed in patients with an MRC-SS of less than 48 at ICU discharge. We investigated the correlations between the MRC-SS at ICU discharge and the long-term clinical outcomes. Results: We included 26 patients, with 13 having ICU-AW. In the long-term follow-up, the ICU-AW group had significantly lower scores than the no ICU-AW group in the SF-36 subscales such as Physical Functioning (PF), Role Limitation-Physical (RP), Bodily Pain (BP), Vitality (VT), Social Functioning (SF), and Role Limitation-Emotional (RE), as well as in the Physical Component Summary Score (PCS). The muscle strength was also decreased in the ICU-AW group. The MRC-SS at ICU discharge was positively correlated with PF, RP, BP, SF, RE, and PCS in SF-36 at the 18-month follow-up. Conclusions: COVID-19 survivors with ICU-AW experienced a long-term decline in HRQOL, and muscle weakness at ICU discharge was correlated with the long-term HRQOL.
摘要 目的:本研究调查了被诊断为重症监护室获得性肌无力(ICU-AW)的冠状病毒 2019(COVID-19)幸存者的长期健康相关生活质量(HRQOL)和身体功能。评估ICU出院时肌无力与HRQOL之间的相关性。研究方法对2021年1月至2021年11月期间入住兵库医科大学医院重症监护室的COVID-19患者进行了一项回顾性研究。使用 SF-36 问卷对患者的 HRQOL 进行评估,并在患者发病 18 个月后对其身体功能进行评估,包括通过医学研究委员会总分(MRC-SS)评估的肌肉力量、握力和 6 分钟步行距离(6MWD)。在 ICU 出院时,MRC-SS 小于 48 分的患者被诊断为 ICU-AW。我们研究了 ICU 出院时的 MRC-SS 与长期临床结果之间的相关性。研究结果我们共纳入了 26 例患者,其中 13 例患有 ICU-AW。在长期随访中,ICU-AW 组的 SF-36 分量表(如身体功能 (PF)、角色限制-身体 (RP)、身体疼痛 (BP)、活力 (VT)、社会功能 (SF) 和角色限制-情感 (RE))以及身体成分总分 (PCS) 均明显低于无 ICU-AW 组。ICU-AW 组的肌肉力量也有所下降。在 18 个月的随访中,ICU 出院时的 MRC-SS 与 SF-36 中的 PF、RP、BP、SF、RE 和 PCS 呈正相关。结论患有 ICU-AW 的 COVID-19 幸存者的长期 HRQOL 有所下降,ICU 出院时的肌无力与长期 HRQOL 相关。
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引用次数: 0
Association of Preoperative Osteoporotic Vertebral Compression Fractures with Muscle Atrophy in Lumbar Spinal Stenosis: A Retrospective Cohort Study. 腰椎管狭窄症患者术前骨质疏松性椎体压缩骨折与肌肉萎缩的关系:回顾性队列研究
Pub Date : 2024-03-29 eCollection Date: 2024-01-01 DOI: 10.2490/prm.20240011
Kenta Suzuki, Yasuaki Mizoguchi, Yuki Hasebe, Fumihiko Kimura, Kazuo Saita, Satoshi Ogihara

Objectives: Osteoporotic vertebral compression fractures (OVCFs) are common in older individuals and lead to pain, spinal deformities, and limited mobility. Paraspinal muscle function correlates with fracture severity, and this association may be more significant in patients with lumbar spinal stenosis (LSS). However, studies on the effects of OVCFs are lacking. This study aimed to investigate the relationship between OVCFs, fat infiltration, and muscle atrophy in patients with LSS.

Methods: This study included 177 patients with preoperative LSS, of whom 16 had OVCFs and 161 did not. Lumbar lordosis angle, fat infiltration, and paraspinal muscle atrophy were evaluated in these patients. Information on patient characteristics such as smoking, diabetes, hemodialysis, steroid use, American Society of Anesthesiologists score, and bladder or bowel dysfunction were obtained from medical records. Logistic regression analysis was conducted to identify factors independently associated with OVCF.

Results: Patients in the OVCF group were significantly older (P=0.006) than those without fractures, and a higher proportion of the OVCF group showed muscle atrophy (P=0.034). Significant variables and those with moderate effect sizes were included in the logistic regression analysis. Muscle atrophy (P=0.028) was independently associated with OVCF.

Conclusions: Muscle atrophy was associated with preoperative OVCFs in patients with LSS. Identifying OVCFs in these patients may underscore the importance of tailored treatment and rehabilitation strategies for the paraspinal muscles.

目的:骨质疏松性椎体压缩骨折(OVCF)在老年人中很常见,会导致疼痛、脊柱畸形和活动受限。脊柱旁肌肉功能与骨折严重程度相关,这种关联在腰椎管狭窄症(LSS)患者中可能更为显著。然而,目前还缺乏有关 OVCF 影响的研究。本研究旨在探讨腰椎管狭窄症患者OVCFs、脂肪浸润和肌肉萎缩之间的关系:本研究纳入了 177 名术前 LSS 患者,其中 16 人有 OVCF,161 人没有。对这些患者的腰椎前凸角度、脂肪浸润和脊柱旁肌肉萎缩情况进行了评估。从病历中获取了患者的特征信息,如吸烟、糖尿病、血液透析、类固醇使用、美国麻醉医师协会评分、膀胱或肠道功能障碍等。进行了逻辑回归分析,以确定与 OVCF 独立相关的因素:OVCF组患者的年龄明显大于无骨折组(P=0.006),OVCF组中出现肌肉萎缩的比例更高(P=0.034)。显著变量和影响大小适中的变量被纳入逻辑回归分析。肌肉萎缩(P=0.028)与OVCF独立相关:结论:肌肉萎缩与 LSS 患者术前的 OVCF 相关。在这些患者中识别 OVCF 可能会强调针对脊柱旁肌肉的定制治疗和康复策略的重要性。
{"title":"Association of Preoperative Osteoporotic Vertebral Compression Fractures with Muscle Atrophy in Lumbar Spinal Stenosis: A Retrospective Cohort Study.","authors":"Kenta Suzuki, Yasuaki Mizoguchi, Yuki Hasebe, Fumihiko Kimura, Kazuo Saita, Satoshi Ogihara","doi":"10.2490/prm.20240011","DOIUrl":"https://doi.org/10.2490/prm.20240011","url":null,"abstract":"<p><strong>Objectives: </strong>Osteoporotic vertebral compression fractures (OVCFs) are common in older individuals and lead to pain, spinal deformities, and limited mobility. Paraspinal muscle function correlates with fracture severity, and this association may be more significant in patients with lumbar spinal stenosis (LSS). However, studies on the effects of OVCFs are lacking. This study aimed to investigate the relationship between OVCFs, fat infiltration, and muscle atrophy in patients with LSS.</p><p><strong>Methods: </strong>This study included 177 patients with preoperative LSS, of whom 16 had OVCFs and 161 did not. Lumbar lordosis angle, fat infiltration, and paraspinal muscle atrophy were evaluated in these patients. Information on patient characteristics such as smoking, diabetes, hemodialysis, steroid use, American Society of Anesthesiologists score, and bladder or bowel dysfunction were obtained from medical records. Logistic regression analysis was conducted to identify factors independently associated with OVCF.</p><p><strong>Results: </strong>Patients in the OVCF group were significantly older (P=0.006) than those without fractures, and a higher proportion of the OVCF group showed muscle atrophy (P=0.034). Significant variables and those with moderate effect sizes were included in the logistic regression analysis. Muscle atrophy (P=0.028) was independently associated with OVCF.</p><p><strong>Conclusions: </strong>Muscle atrophy was associated with preoperative OVCFs in patients with LSS. Identifying OVCFs in these patients may underscore the importance of tailored treatment and rehabilitation strategies for the paraspinal muscles.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"9 ","pages":"20240011"},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10984831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Tongue Strength Training on Patients with Mild to Moderate Sleep-disordered Breathing: A Randomized Controlled Trial. 舌肌力训练对轻度至中度睡眠呼吸障碍患者的影响:随机对照试验。
Pub Date : 2024-03-23 eCollection Date: 2024-01-01 DOI: 10.2490/prm.20240010
Junya Yoshioka, Tatsuya Nagano, Reina Sekiya, Chihiro Mimura, Hiroki Satoh, Takehiro Otoshi, Daisuke Hazama, Naoko Katsurada, Masatsugu Yamamoto, Motoko Tachihara, Yoshihiro Nishimura, Kazuyuki Kobayashi

Objectives: : Several studies have reported that oropharyngeal myofunctional therapy (OMT) reduces the severity of obstructive sleep apnea (OSA). However, because OMT protocols are often complicated, they take time and effort to implement. The aim of this study was to determine the therapeutic effect of 8 weeks of simple tongue strength training with a training device.

Methods: : Twenty patients with mild to moderate sleep-disordered breathing were randomized to the control group (n=10) or intervention group (n=10). The patients in the intervention group completed 8 weeks of daily tongue strength training using a training device. After 8 weeks, we evaluated each patient for sleep-disordered breathing by portable monitoring. We also evaluated each patient's body mass index (BMI), neck circumference, Epworth Sleepiness Scale (ESS) score, and tongue pressure.

Results: No significant difference was found in the change in apnea hypopnea index (AHI) from baseline to 8 weeks between the control and intervention groups (P=0.44). However, the changes in neck circumference (P=0.02) and maximum tongue pressure (P=0.03) from baseline to 8 weeks were significantly different between the two groups. No significant difference was found for changes in BMI and ESS scores from baseline to 8 weeks between the two groups.

Conclusions: : Tongue strength training in patients with sleep-disordered breathing did not significantly improve AHI as measured by portable monitoring, although significant changes were observed for increased tongue pressure and reduced neck circumference.

目的: :多项研究表明,口咽肌功能疗法(OMT)可减轻阻塞性睡眠呼吸暂停(OSA)的严重程度。然而,由于口咽肌功能疗法的治疗方案通常比较复杂,因此实施起来费时费力。本研究旨在确定使用训练装置进行为期 8 周的简单舌力训练的治疗效果:将 20 名轻度至中度睡眠呼吸障碍患者随机分为对照组(10 人)或干预组(10 人)。干预组患者使用训练装置完成为期8周的日常舌力训练。8 周后,我们通过便携式监测仪对每位患者的睡眠呼吸障碍情况进行评估。我们还评估了每位患者的体重指数(BMI)、颈围、埃普沃斯嗜睡量表(ESS)评分和舌压:结果:对照组和干预组的呼吸暂停低通气指数(AHI)从基线到 8 周的变化无明显差异(P=0.44)。然而,两组间颈围(P=0.02)和最大舌压(P=0.03)从基线到 8 周的变化有显著差异。两组患者的体重指数和ESS评分从基线到8周的变化无明显差异:结论:对睡眠呼吸障碍患者进行舌部力量训练并不能明显改善便携式监测仪测量的AHI,但在增加舌压和减少颈围方面观察到了显著变化。
{"title":"Effects of Tongue Strength Training on Patients with Mild to Moderate Sleep-disordered Breathing: A Randomized Controlled Trial.","authors":"Junya Yoshioka, Tatsuya Nagano, Reina Sekiya, Chihiro Mimura, Hiroki Satoh, Takehiro Otoshi, Daisuke Hazama, Naoko Katsurada, Masatsugu Yamamoto, Motoko Tachihara, Yoshihiro Nishimura, Kazuyuki Kobayashi","doi":"10.2490/prm.20240010","DOIUrl":"10.2490/prm.20240010","url":null,"abstract":"<p><strong>Objectives: </strong>: Several studies have reported that oropharyngeal myofunctional therapy (OMT) reduces the severity of obstructive sleep apnea (OSA). However, because OMT protocols are often complicated, they take time and effort to implement. The aim of this study was to determine the therapeutic effect of 8 weeks of simple tongue strength training with a training device.</p><p><strong>Methods: </strong>: Twenty patients with mild to moderate sleep-disordered breathing were randomized to the control group (n=10) or intervention group (n=10). The patients in the intervention group completed 8 weeks of daily tongue strength training using a training device. After 8 weeks, we evaluated each patient for sleep-disordered breathing by portable monitoring. We also evaluated each patient's body mass index (BMI), neck circumference, Epworth Sleepiness Scale (ESS) score, and tongue pressure.</p><p><strong>Results: </strong>No significant difference was found in the change in apnea hypopnea index (AHI) from baseline to 8 weeks between the control and intervention groups (P=0.44). However, the changes in neck circumference (P=0.02) and maximum tongue pressure (P=0.03) from baseline to 8 weeks were significantly different between the two groups. No significant difference was found for changes in BMI and ESS scores from baseline to 8 weeks between the two groups.</p><p><strong>Conclusions: </strong>: Tongue strength training in patients with sleep-disordered breathing did not significantly improve AHI as measured by portable monitoring, although significant changes were observed for increased tongue pressure and reduced neck circumference.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"9 ","pages":"20240010"},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10961225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Progress in rehabilitation medicine
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