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Effect of Diet and Dietary Patterns on the Progression of Multiple Sclerosis: A Review. 饮食和饮食模式对多发性硬化症进展的影响:综述。
Pub Date : 2025-01-01 DOI: 10.2174/012772574X325602240910075218
Rabie Khattab, Arafat Goja, Welayah AlAmmar

The link between diet and the progression of Multiple Sclerosis (MS) is a topic of growing interest and investigation within the medical community. This review explored the mechanisms through which dietary interventions can impact the course of MS and shape the clinical outcomes and quality of life of individuals with the disease. By synthesizing current knowledge from clinical studies and observational research, the review aimed to provide insights into the role of diet in managing MS. A comprehensive literature search was conducted, focusing on the effect of diet and dietary patterns on the progression of MS. Key findings indicated that individuals with higher diet quality exhibit reduced disability levels and lower symptom severity, emphasizing the importance of maintaining a healthy diet and adopting a holistic, healthy lifestyle in managing MS. The review also delved into the potential impact of macronutrients, vitamins, and minerals on the progression of MS, highlighting the importance of adequate nutrient intake for optimal health outcomes. Additionally, the study explored the association between dietary intake variations and the severity of MS, suggesting that further investigation is needed to understand the potential implications of nutrient deficiencies in MS patients. Overall, the review serves as a valuable resource for healthcare professionals and individuals living with MS, providing evidence-based dietary approaches that may help optimize health outcomes and mitigate the burden of the disease. It also calls for future research directions in the critical area of dietary management of MS to enhance our understanding and improve patient care.

饮食与多发性硬化症(MS)的进展之间的联系是医学界日益关注和研究的一个课题。本综述探讨了饮食干预对多发性硬化症的病程、临床结果和患者生活质量的影响机制。通过综合临床研究和观察性研究的现有知识,该综述旨在提供饮食在多发性硬化症管理中的作用的洞察力。我们进行了全面的文献检索,重点关注饮食和饮食模式对多发性硬化症进展的影响。主要研究结果表明,饮食质量越高的人,残疾程度越低,症状严重程度越轻,这强调了保持健康饮食和采取全面健康的生活方式对控制多发性硬化症的重要性。综述还深入探讨了宏量营养素、维生素和矿物质对多发性硬化症进展的潜在影响,强调了充足的营养摄入对获得最佳健康结果的重要性。此外,该研究还探讨了膳食摄入量的变化与多发性硬化症严重程度之间的关联,表明需要进一步调查以了解营养素缺乏对多发性硬化症患者的潜在影响。总之,该综述为医疗保健专业人员和多发性硬化症患者提供了宝贵的资源,提供了以证据为基础的饮食方法,有助于优化健康结果和减轻疾病负担。它还呼吁未来在多发性硬化症饮食管理这一关键领域的研究方向,以增强我们的理解并改善患者护理。
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引用次数: 0
Chitosan and Chitosan-Essential Oil Composites as Edible Coatings for Meat and Meat Products: A Review. 壳聚糖和壳聚糖-精油复合材料作为肉类和肉制品的食用涂层:综述。
Pub Date : 2025-01-01 DOI: 10.2174/012772574X301555240503070126
Mohamed Abd Elgadir, Mohamed E S Mirghani, Abdalbasit Mariod

The massive and uncontrolled use of petroleum-based plastic food packaging has resulted in serious environmental problems. As a result, the food packaging industry should improve packaging materials based on biodegradable polymers, such as chitosan. Edible food coating maintains and improves the shelf life and condition of packaged foods. Researchers have widely investigated the potential applications of biodegradable natural polymers, such as chitosan, cellulose, starch, whey protein, and gelatin in the food packaging industry. Among the natural biodegradable materials available, chitosan and its derivatives have attracted great interest because they have antimicrobial, antifungal, and metal-chelating properties. They are biodegradable polysaccharides and are non-toxic; therefore, they are considered perfect materials for food coating. Adding other active materials, such as fruit extracts, phenolic compounds, and essential oils, can significantly enhance the antimicrobial and antioxidant capacity of chitosan-based packaging materials. Thus, this article investigates the recent updates in food packaging applications based on chitosan essential oil composites.

石油基塑料食品包装的大量无节制使用导致了严重的环境问题。因此,食品包装行业应改进基于可生物降解聚合物(如壳聚糖)的包装材料。可食用食品涂层可以保持和改善包装食品的保质期和状态。研究人员广泛研究了壳聚糖、纤维素、淀粉、乳清蛋白和明胶等可生物降解的天然聚合物在食品包装行业的潜在应用。在可生物降解的天然材料中,壳聚糖及其衍生物因具有抗菌、防霉和螯合金属的特性而备受关注。它们是可生物降解的多糖,而且无毒,因此被认为是食品涂层的理想材料。添加其他活性材料,如水果提取物、酚类化合物和精油,可显著提高壳聚糖基包装材料的抗菌和抗氧化能力。因此,本文研究了基于壳聚糖精油复合材料的食品包装应用的最新进展。
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引用次数: 0
Current State of Scientific Knowledge on Curcumin Encapsulation and Applications. 姜黄素封装和应用的科学现状。
Pub Date : 2025-01-01 DOI: 10.2174/012772574X330008240827052241
Wissam Zam, Mohamed Reda Zahi, Mohamed El Hattab

The yellow pigment curcumin has long been used in traditional medicine for its anti-inflammatory, antibacterial and antioxidant activities. Over the past half-century, scientific investigations have shown that curcumin is endowed with additional health benefits because it can modify key molecular targets associated with a number of pathologies, such as diabetes, cancer, and arthritis, in addition to cardiovascular, multiple sclerosis, Alzheimer's, and Crohn's diseases. However, this molecule has several disadvantages, such as low bioavailability and solubility, severe oxidative destruction, light sensitivity, fast systemic clearance and breakdown at alkaline pH levels. To address these drawbacks, several methods of microencapsulation employing a variety of shell materials have been investigated. These techniques contributed toward the increase of curcumin's solubility and stability against heat, light, oxygen, and an alkaline pH. The various shell materials and methods used to microencapsulate this chemical are the main topics of this review. The use of microencapsulated curcumin in food, medicine, and cosmetics is also discussed in more detail. Recent relevant research from the last few years has been given in this area, along with future difficulties.

姜黄素是一种黄色色素,因其具有消炎、抗菌和抗氧化作用而长期被用于传统医学。在过去的半个世纪里,科学研究表明姜黄素具有更多的健康益处,因为它可以改变与糖尿病、癌症、关节炎等多种病症相关的关键分子靶点,此外还能改变心血管疾病、多发性硬化症、阿尔茨海默氏症和克罗恩病等疾病的分子靶点。然而,这种分子也有一些缺点,如生物利用度和溶解度低、氧化破坏严重、对光敏感、全身清除快以及在碱性 pH 水平下分解。为了解决这些缺点,人们研究了几种采用各种外壳材料的微囊化方法。这些技术有助于提高姜黄素的溶解度和稳定性,使其不受热、光、氧和碱性 pH 值的影响。用于微囊化这种化学物质的各种外壳材料和方法是本综述的主要内容。此外,还详细讨论了微胶囊姜黄素在食品、医药和化妆品中的应用。此外,还介绍了过去几年在这一领域的最新研究成果以及未来的困难。
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引用次数: 0
Cholesterol Absorption Inhibition by Some Nutraceuticals. 某些保健食品对胆固醇吸收的抑制作用
Pub Date : 2025-01-01 DOI: 10.2174/012772574X285280240220065812
Shivendra Kumar, Sunam Saha, Devender Pathak, Talever Singh, Atul Kumar, Kuldeep Singh, Avinash Kumar Mishra, Sakshi Singh, Shubham Singh

Hyperlipidemia, characterized by elevated levels of lipids in the blood, represents a major risk factor for cardiovascular diseases, a leading cause of morbidity and mortality worldwide. Conventional pharmacological interventions have been effective in managing hyperlipidemia, but concerns about side effects and long-term use have prompted interest in alternative approaches, particularly the use of nutraceuticals. This comprehensive review aims to summarize and critically evaluate the current body of knowledge surrounding the role of nutraceuticals in the management of hyperlipidemia. We provide an overview of the different classes of nutraceuticals, including plant sterols, omega-3 fatty acids, soluble fiber, antioxidants, and various herbal extracts, which have been investigated for their lipid-lowering properties. The mechanisms of action of these nutraceuticals are discussed, highlighting their ability to modulate lipid metabolism, reduce oxidative stress, and promote cardiovascular health. Furthermore, we review the results of clinical trials and epidemiological studies that have assessed the efficacy of nutraceutical interventions in lowering cholesterol levels, improving lipid profiles, and reducing the risk of cardiovascular events. In addition to their lipid-lowering effects, we examine the safety profile, dosage recommendations, and potential interactions of nutraceuticals with conventional lipid-lowering medications. We also address the importance of patient adherence to dietary and lifestyle modifications in conjunction with nutraceutical supplementation. While nutraceuticals offer a promising avenue for managing hyperlipidemia, we emphasize the need for further research to establish evidence-based guidelines for their use in clinical practice. Challenges related to standardization, quality control, and regulatory considerations are also discussed. In conclusion, this comprehensive review provides valuable insights into the potential of nutraceuticals as adjunctive or alternative therapies for managing hyperlipidemia. While further research is needed, the accumulating evidence suggests that nutraceuticals can play a valuable role in promoting cardiovascular health and reducing the burden of hyperlipidemia-related diseases.

高脂血症的特点是血液中血脂水平升高,是心血管疾病的主要风险因素,也是全球发病率和死亡率的主要原因。传统的药物干预在控制高脂血症方面效果显著,但副作用和长期使用等问题引起了人们对替代方法的关注,尤其是营养保健品的使用。本综述旨在总结和批判性评估当前围绕营养保健品在高脂血症治疗中作用的知识体系。我们概述了不同类别的营养保健品,包括植物固醇、ω-3 脂肪酸、可溶性纤维、抗氧化剂和各种草药提取物,这些营养保健品都具有降脂功效。我们讨论了这些营养保健品的作用机制,强调了它们调节脂质代谢、减少氧化应激和促进心血管健康的能力。此外,我们还回顾了临床试验和流行病学研究的结果,这些研究评估了营养保健品干预措施在降低胆固醇水平、改善血脂状况和降低心血管事件风险方面的功效。除了降脂效果外,我们还研究了营养保健品的安全性、剂量建议以及与传统降脂药物的潜在相互作用。我们还探讨了患者在补充营养保健品的同时坚持饮食和生活方式调整的重要性。虽然营养保健品为控制高脂血症提供了一条前景广阔的途径,但我们强调仍需进一步研究,为其在临床实践中的使用制定循证指南。此外,我们还讨论了标准化、质量控制和监管方面的挑战。总之,本综述对营养保健品作为控制高脂血症的辅助或替代疗法的潜力提供了宝贵的见解。虽然还需要进一步的研究,但不断积累的证据表明,营养保健品在促进心血管健康和减轻高脂血症相关疾病的负担方面可以发挥宝贵的作用。
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引用次数: 0
Unveiling the Compositional Analysis of Green Coffee Beans with and without Silver Skin. 揭开有银皮和无银皮绿咖啡豆成分分析的神秘面纱
Pub Date : 2025-01-01 DOI: 10.2174/012772574X293155240226095030
Shraddha Tripathi, Neha Mishra, Ritika Malaviya, Arshi Ansari, Simran Shrimali, Neetu Mishra

Background: Green Coffee Bean (GCB) is covered with silver skin that is shed as a by-product of the roasting process. For the first time, a comparative study was conducted to differentiate the compositional analysis of green coffee beans with silver skin and without silver skin.

Objective: The study aims comparatively assessing nutritional, anti-nutritional and fatty acids composition of green coffee beans with silver skin and without silver skin. The present study is also intended to find out various organic compounds of green coffee beans.

Methods: The proximate analysis was used to study nutritional composition. Mineral analysis was assessed by atomic absorption spectroscopy. The antinutrients like phytic acid and tannin were assessed by UV-visible spectroscopy whereas volumetric and gravimetric analysis was used to determine oxalates and alkaloids. Gas chromatography and Fourier Transform Infra-Red spectroscopy were used for studying fatty acids and organic compounds, respectively.

Results: Protein content was significantly (p<0.05) high in green coffee beans with silver skin, indicating 15% higher protein. Macro mineral content was also found significantly (p<0.05 and p<0.01) high in green coffee beans with silver skin, whereby 5.11% higher Phosphorus and 24.12% higher Calcium content was observed. However, iron content was 68.10% lower in green coffee beans with silver skin which might be due to its higher tannin content. Trace minerals zinc and copper were also found to contain 57.18% to 18.11% higher concentrations respectively in silver skin. Anti-nutritional analysis revealed the content of phytic acid and tannin as 161 and 77.29 mg/100g, respectively in green coffee beans with silver skin. The percentages of oxalates and alkaloids were found to be 0.64 and 14.30. These anti-nutritional compounds were significantly (p<0.05 and p<0.01) higher from green coffee beans without silver skin. Green coffee beans have been found with an utmost number of saturated fatty acids having palmitic acid as the most abundant. The unsaturated part is mainly composed of linoleic and oleic acid. Chlorogenic acid isomers and caffeine were the organic compounds detected through Fourier transform infrared spectroscopy.

Conclusion: These findings reveal the presence of both nutritional and anti-nutritional components in Coffee silver skin, with significantly higher levels of anti-nutritional factors in green coffee with silver skin, emphasizing the need for caution in the consumption of green coffee and utilization of coffee silver skin as a valuable bioresource.

背景:绿咖啡豆(GCB)表面覆盖着银皮,这是烘焙过程中脱落的副产品。本研究首次对有银皮和无银皮绿咖啡豆的成分进行了比较分析:本研究旨在比较评估有银皮和无银皮绿咖啡豆的营养、抗营养和脂肪酸成分。本研究还旨在找出绿咖啡豆中的各种有机化合物:方法:采用近似分析法研究营养成分。矿物质分析采用原子吸收光谱进行评估。植酸和单宁等抗营养素采用紫外可见光谱法进行评估,而草酸盐和生物碱则采用容量和重量分析法进行测定。气相色谱法和傅立叶变换红外光谱法分别用于研究脂肪酸和有机化合物:结果:蛋白质含量明显偏低(p这些研究结果表明,咖啡银皮中既含有营养成分,也含有抗营养成分,含银皮的绿咖啡中的抗营养因子水平明显更高,这强调了在饮用绿咖啡时需要谨慎,并将咖啡银皮作为一种宝贵的生物资源加以利用。
{"title":"Unveiling the Compositional Analysis of Green Coffee Beans with and without Silver Skin.","authors":"Shraddha Tripathi, Neha Mishra, Ritika Malaviya, Arshi Ansari, Simran Shrimali, Neetu Mishra","doi":"10.2174/012772574X293155240226095030","DOIUrl":"10.2174/012772574X293155240226095030","url":null,"abstract":"<p><strong>Background: </strong>Green Coffee Bean (GCB) is covered with silver skin that is shed as a by-product of the roasting process. For the first time, a comparative study was conducted to differentiate the compositional analysis of green coffee beans with silver skin and without silver skin.</p><p><strong>Objective: </strong>The study aims comparatively assessing nutritional, anti-nutritional and fatty acids composition of green coffee beans with silver skin and without silver skin. The present study is also intended to find out various organic compounds of green coffee beans.</p><p><strong>Methods: </strong>The proximate analysis was used to study nutritional composition. Mineral analysis was assessed by atomic absorption spectroscopy. The antinutrients like phytic acid and tannin were assessed by UV-visible spectroscopy whereas volumetric and gravimetric analysis was used to determine oxalates and alkaloids. Gas chromatography and Fourier Transform Infra-Red spectroscopy were used for studying fatty acids and organic compounds, respectively.</p><p><strong>Results: </strong>Protein content was significantly (p<0.05) high in green coffee beans with silver skin, indicating 15% higher protein. Macro mineral content was also found significantly (p<0.05 and p<0.01) high in green coffee beans with silver skin, whereby 5.11% higher Phosphorus and 24.12% higher Calcium content was observed. However, iron content was 68.10% lower in green coffee beans with silver skin which might be due to its higher tannin content. Trace minerals zinc and copper were also found to contain 57.18% to 18.11% higher concentrations respectively in silver skin. Anti-nutritional analysis revealed the content of phytic acid and tannin as 161 and 77.29 mg/100g, respectively in green coffee beans with silver skin. The percentages of oxalates and alkaloids were found to be 0.64 and 14.30. These anti-nutritional compounds were significantly (p<0.05 and p<0.01) higher from green coffee beans without silver skin. Green coffee beans have been found with an utmost number of saturated fatty acids having palmitic acid as the most abundant. The unsaturated part is mainly composed of linoleic and oleic acid. Chlorogenic acid isomers and caffeine were the organic compounds detected through Fourier transform infrared spectroscopy.</p><p><strong>Conclusion: </strong>These findings reveal the presence of both nutritional and anti-nutritional components in Coffee silver skin, with significantly higher levels of anti-nutritional factors in green coffee with silver skin, emphasizing the need for caution in the consumption of green coffee and utilization of coffee silver skin as a valuable bioresource.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":"99-108"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140102969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Potential of Carotenoids in Obesity Management: A Comprehensive Overview. 探索类胡萝卜素在肥胖症控制中的潜力:全面概述。
Pub Date : 2025-01-01 DOI: 10.2174/012772574X310316240610111659
Vanshika Rastogi, Shashank Soni

Obesity is a global health concern with numerous comorbidities, including cardiovascular diseases, type 2 diabetes, and certain cancers. Carotenoids, found in a variety of natural sources like fruits and vegetables, are known for their potential health benefits. Emerging research suggests that certain carotenoids may play a major role in combating obesity through mechanisms involving inflammation, oxidative stress, and lipid metabolism. Understanding the influence of carotenoids on metabolic health could offer valuable revelation about obesity management strategies. To summarize the main findings on carotenoids that help in the management and prevention of obesity, exploring their potential benefits in weight management, metabolic health, and overall well-being. An extensive literature survey was done on the management of obesity using PubMed, Elsevier, ScienceDirect, and Springer. The results were then filtered based on the titles, abstracts, and accessibility of the complete texts. The search engine Google Scholar was accessed for the literature data mining. This review highlights the diverse functions of carotenoids, such as their antioxidant properties, antiinflammatory effects, and regulation of lipid metabolism, which contribute to their potential role in combating obesity. Studies suggest that carotenoids may help reduce adiposity, lipid accumulation, improve insulin sensitivity, and promote overall metabolic health, making them promising candidates for obesity management. Obesity is synonymous with the appearance of major diseases and an overall decline in physical and mental performance. Overall, the findings of this review endorse the possible application of carotenoids as a nutritional supplement for the management and prevention of obesity. Further research is needed to clarify the mechanisms underlying the beneficial impacts of carotenoids on obesity-related consequences and to optimize their utilization in clinical practice and public health campaigns.

肥胖症是一个全球性的健康问题,会引发多种并发症,包括心血管疾病、2 型糖尿病和某些癌症。类胡萝卜素存在于水果和蔬菜等多种天然来源中,以其潜在的健康益处而闻名。新的研究表明,某些类胡萝卜素可能通过涉及炎症、氧化应激和脂质代谢的机制在对抗肥胖方面发挥重要作用。了解类胡萝卜素对代谢健康的影响可为肥胖管理策略提供有价值的启示。为了总结有助于控制和预防肥胖的类胡萝卜素的主要研究成果,探索其在体重控制、代谢健康和整体健康方面的潜在益处。我们利用 PubMed、Elsevier、ScienceDirect 和 Springer 对有关肥胖管理的文献进行了广泛调查。然后根据标题、摘要和全文的可读性对结果进行筛选。在进行文献数据挖掘时,还使用了搜索引擎 Google Scholar。这篇综述强调了类胡萝卜素的多种功能,如抗氧化特性、抗炎作用和调节脂质代谢,这些都有助于类胡萝卜素在对抗肥胖方面发挥潜在作用。研究表明,类胡萝卜素可能有助于减少脂肪和脂质堆积,改善胰岛素敏感性,促进整体代谢健康,因此类胡萝卜素有望成为控制肥胖的候选物质。肥胖与重大疾病的出现以及体能和智能的整体下降是同义词。总之,本综述的研究结果支持将类胡萝卜素作为一种营养补充剂用于控制和预防肥胖症。还需要进一步的研究来阐明类胡萝卜素对肥胖相关后果产生有益影响的机制,并优化其在临床实践和公共卫生运动中的应用。
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引用次数: 0
Impact of High Pressure Processing on the Safety and Quality of Food Products: A Review. 高压加工对食品安全和质量的影响:综述。
Pub Date : 2025-01-01 DOI: 10.2174/012772574X289005240215093457
Hanna Khouryieh

High pressure processing (HPP) has become a practical food processing technique that meets the preferences of consumers seeking lightly processed, convenient, and fresh-tasting food options. This paper reviewed the latest research on the impact of HPP on the safety and quality of food products. The use of HPP has been showing favorable growth in the food industry primarily due to its potential to not only enhance the nutritional content and sensory attributes of food products but also to substantially extend their shelf-life and bolster safety standards. HPP is the most used among non-thermal food processing technologies. While its direct application to milk for consumption falls short of delivering consistent quality, it proves effective as a pre-treatment step and in products using milk as a primary ingredient. In the context of meat production, HPP reduces microbial loads and extends shelf-life, yet concerns persist regarding its impact on product quality. The absence of in-depth studies regarding the attributes of carrots that support pathogen regeneration emphasizes the need for comprehensive research in this area, which could have far-reaching implications for similar fruit and vegetable products. This review underscores the need for a balanced assessment of HPP's effects on food safety and quality, offering insights that can guide the food industry in adopting this technology while ensuring consumer satisfaction and safety.

高压加工(HPP)已成为一种实用的食品加工技术,可满足消费者对轻度加工、方便和新鲜口感食品的偏好。本文综述了有关 HPP 对食品安全和质量影响的最新研究。HPP 的使用在食品行业一直呈现出良好的增长势头,这主要是因为它不仅可以提高食品的营养成分和感官属性,还能大大延长食品的保质期并提高安全标准。在非热加工食品技术中,HPP 的应用最为广泛。虽然直接应用于食用牛奶并不能提供稳定的质量,但作为预处理步骤以及在以牛奶为主要成分的产品中,它被证明是有效的。在肉类生产中,HPP 可减少微生物负荷并延长保质期,但其对产品质量的影响仍令人担忧。由于缺乏对胡萝卜支持病原体再生的特性的深入研究,因此强调了在这一领域开展全面研究的必要性,这可能会对类似的果蔬产品产生深远影响。本综述强调有必要对 HPP 对食品安全和质量的影响进行平衡评估,并提供一些见解,以指导食品行业在采用该技术的同时确保消费者的满意度和安全性。
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引用次数: 0
Assessing Recent Technologies for Addressing Microplastic Pollution and Pushing the Case of Bioremediation as an Attractive Approach. 评估解决微塑料污染的最新技术,并将生物修复作为一种有吸引力的方法。
Pub Date : 2025-01-01 DOI: 10.2174/012772574X313370240620072831
Ekta Bhatt, Pammi Gauba, Indira P Sarethy

Microplastics are emerging sources of environmental pollutants that are increasingly of concern because of their harmful impacts on aquatic life and thereby humans. Their accumulation in the environment is in direct proportion to global plastic production; their being nondegradable, recalcitrant and of a persistent nature creates an urgent need to address this issue on a global scale. Recent reports have demonstrated the presence of microplastics in marine life, and directly becoming a part of the food chain when seafood is ingested by humans. The repercussions of these studies point to an even larger scale presence of microplastics across varied habitats, which are yet to be sampled. Bioremediation, using various microorganisms such as bacteria, algae and fungi, alone or as consortia or in biofilm form can be used as an effective remediation tool. Genetically modified microorganisms for focused removal of microplastics and metagenomics studies, providing taxonomic details of uncultured organisms, are also expected to provide an additional catalogue of technologies in this field. This review offers a comprehensive overview of microplastic sources, existing technologies for treating microplastics and an in-depth analysis of bioremediation mechanisms, its components, and the results from various studies which provide sufficient clues as to the directions to be chosen to address microplastics pollution and can facilitate and instruct researchers to further investigate the more practical approaches and create new and innovative strategies for advanced remediation of microplastic in the future.

微塑料是新出现的环境污染物来源,由于其对水生生物和人类的有害影响而日益受到关注。微塑料在环境中的累积量与全球塑料产量成正比;微塑料具有不可降解性、难降解性和持久性,因此迫切需要在全球范围内解决这一问题。最近的报告显示,海洋生物中存在微塑料,当人类摄入海产品时,微塑料直接成为食物链的一部分。这些研究的反响表明,微塑料在各种栖息地的存在规模更大,而这些栖息地尚有待采样。利用细菌、藻类和真菌等各种微生物,单独或以联合体或生物膜形式进行生物修复,可作为一种有效的修复工具。用于集中清除微塑料的转基因微生物和元基因组学研究(提供未培养生物的分类详情)也有望为该领域提供更多的技术目录。本综述全面概述了微塑料的来源、处理微塑料的现有技术,并深入分析了生物修复机制、其组成部分以及各种研究的结果,为解决微塑料污染问题提供了充分的线索,有助于并指导研究人员进一步研究更实用的方法,并在未来为先进的微塑料修复技术创造新的创新战略。
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引用次数: 0
Antioxidants for Skin Health. 抗氧化剂促进皮肤健康
Pub Date : 2025-01-01 DOI: 10.2174/012772574X311177240710100118
Virender Kumar, Neha Tanwar, Muskan Goel, Mohit Khan, Davinder Kumar, Gajendra Singh, Jyoti Mundlia, Naveen Khatri, Ashwani Kumar
<p><p>Antioxidants play a pivotal role in maintaining skin health and integrity, combating the deleterious effects of oxidative stress induced by environmental aggressors such as UV radiation, pollution, and lifestyle factors. This paper reviews the contributions of key antioxidants, including Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10, Resveratrol, Selenium, and Polyphenols, in skin health care. Vitamin C, known for its collagen synthesis promotion and photoprotection properties, alongside Vitamin E, a lipid-soluble antioxidant, synergistically works to neutralize free radicals and repair damaged skin cells. Vitamin A, in the form of retinol, plays a critical role in skin cell regeneration and the maintenance of skin integrity. Green tea extract, rich in Polyphenols, offers anti-inflammatory and anticarcinogenic properties, making it a potent ingredient for skin protection. Coenzyme Q10, a naturally occurring antioxidant in the body, aids in energy production for cell repair and regeneration, while Resveratrol, found in grapes and berries, provides anti-ageing benefits by enhancing skin's resistance to oxidative stress. Selenium, an essential mineral, contributes to the protection of skin cells from oxidative damage. The incorporation of these antioxidants in skincare products and dietary sources is discussed, highlighting the importance of a holistic approach in skincare regimes. The paper emphasizes the synergy between topical applications and dietary intake of antioxidants, advocating for a comprehensive strategy for promoting skin health and preventing age-related skin alterations. Method: For the review article, a variety of search engines and databases were used to identify relevant articles. Furthermore, for biomedical literature focusing on antioxidants and their effects on skin health, PubMed was used. Moreover, to access a wide range of scholarly articles, including those related to dermatology and skincare, Google Scholar was used. Scopus provides comprehensive coverage of peer-reviewed literature across various scientific disciplines. Web of Science identifies high-impact articles and research on antioxidants in skincare. In addition, for accessing full-text articles on antioxidants and their applications in dermatology, Science Direct was used. The inclusion criteria for the review paper were as follows: only studies published in peer-reviewed journals were included to ensure the credibility and reliability of the information. Articles published in English were considered, to avoid language-related biases and ensure comprehension. Studies published within the last 10 years were included to provide the most current insights into antioxidant research in skincare. Articles must specifically focus on the role of antioxidants (Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10, Resveratrol, Selenium, Polyphenols) in skin health care. Both experimental studies (in vivo and in vitro) and clinical trials
抗氧化剂在维护皮肤健康和完整性、对抗紫外线照射、污染和生活方式等环境因素引起的氧化应激的有害影响方面发挥着关键作用。本文回顾了维生素 C、维生素 E、维生素 A、绿茶提取物、辅酶 Q10、白藜芦醇、硒和多酚等主要抗氧化剂在皮肤保健方面的贡献。维生素 C 因其促进胶原蛋白合成和光保护特性而闻名,与维生素 E(一种脂溶性抗氧化剂)一起协同作用,中和自由基,修复受损的皮肤细胞。视黄醇形式的维生素 A 在皮肤细胞再生和保持皮肤完整性方面发挥着关键作用。绿茶萃取物富含茶多酚,具有抗炎和抗癌作用,是保护皮肤的有效成分。辅酶 Q10 是人体内天然存在的一种抗氧化剂,有助于细胞修复和再生的能量生产,而葡萄和浆果中的白藜芦醇则能增强皮肤对氧化压力的抵抗力,从而起到抗衰老的作用。硒是一种重要的矿物质,有助于保护皮肤细胞免受氧化损伤。本文讨论了将这些抗氧化剂纳入护肤产品和膳食来源的问题,强调了整体方法在护肤疗法中的重要性。本文强调了局部应用和膳食摄入抗氧化剂之间的协同作用,提倡采取综合策略促进皮肤健康和预防与年龄相关的皮肤变化。方法:为了撰写这篇综述文章,我们使用了多种搜索引擎和数据库来查找相关文章。此外,还使用了 PubMed 来检索有关抗氧化剂及其对皮肤健康影响的生物医学文献。此外,为了获取广泛的学术文章,包括与皮肤病学和护肤相关的文章,我们还使用了谷歌学术(Google Scholar)。Scopus 全面覆盖了各科学学科的同行评审文献。Web of Science 可查找有关护肤品中抗氧化剂的高影响力文章和研究。此外,为了获取有关抗氧化剂及其在皮肤病学中的应用的全文文章,还使用了 Science Direct。综述论文的纳入标准如下:只纳入在同行评审期刊上发表的研究,以确保信息的可信度和可靠性。考虑以英文发表的文章,以避免与语言相关的偏见并确保理解性。收录了过去 10 年内发表的研究报告,以便为护肤品中的抗氧化剂研究提供最新的见解。文章必须特别关注抗氧化剂(维生素 C、维生素 E、维生素 A、绿茶提取物、辅酶 Q10、白藜芦醇、硒、多酚)在皮肤保健中的作用。实验研究(体内和体外)和临床试验均包括在内,以提供有关抗氧化效果的全面概述。文章均为全文,以便进行全面的数据提取和分析。综述论文的排除标准如下:不包括未经同行审阅的出版物,如社论、观点文章和非学术性文章。由于潜在的翻译困难和保持一致性,以英语以外的语言发表的文章被排除在外。排除了不关注特定抗氧化剂或其对皮肤健康影响的研究。排除了重复发表的文章,以避免在综述中出现冗余。排除数据不充分或不完整的文章,以确保综述结果的质量和可靠性。
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引用次数: 0
Buckwheat: An Underutilized Himalayan Crop with Multifaceted Nutraceutical Benefits. 荞麦:一种未被充分利用的喜马拉雅作物,具有多方面的营养保健功效。
Pub Date : 2025-01-01 DOI: 10.2174/012772574X323710240719073908
Kirti Raina, Ruchika Kumari, Palak Thakur, Rohit Sharma, Ashun Chaudhary

The human population is growing and alternate food options are needed to provide food and nutritional security to mankind. Reduced agricultural output as a result of climate change and increased demand for grains because of continuous population growth have created a gap between demand and supply of food. Buckwheat is a pseudocereal crop plant with high nutritional value that can be included as an alternate food in our diet. It is a traditional crop plant grown in the high mountains of the Himalayas for food as well as fodder. It completes its life cycle in 3-4 months, so is mostly grown as a second crop in between main crops like maize and barley. It also acts as a green manure by improving the phosphorus content of the soil. Buckwheat has high nutritional value as it is rich in essential amino acids, vitamin B, trace elements, and other nutrients. The main bioactive compounds identified in buckwheat are rutin, quercetin, isoquercetin, d-chiroinositol, resveratol, and vitexin, which are responsible for its pharmacological properties. Research focused on value addition by exploring its nutritional, pharmaceutical, and other alternative uses of commercial importance, is needed for reviving buckwheat cultivation practices and its conservation. Considering the multifarious applications of buckwheat, this review summarizes the currently available knowledge on the agronomic and nutraceutical significance of buckwheat to project its value as a future crop in the avenue of agriculture and functional food.

人类人口在不断增长,需要有其他的粮食选择来为人类提供粮食和营养保障。气候变化导致农业产量减少,而人口持续增长又增加了对谷物的需求,这就造成了粮食供需之间的缺口。荞麦是一种假谷类作物,具有很高的营养价值,可以作为我们饮食中的替代食物。荞麦是喜马拉雅山脉高山上种植的一种传统作物,既可作为食物,也可作为饲料。它的生命周期在 3-4 个月内完成,因此大多作为玉米和大麦等主要作物之间的第二茬作物种植。它还能改善土壤中的磷含量,起到绿肥的作用。荞麦富含人体必需的氨基酸、维生素 B、微量元素和其他营养物质,因此具有很高的营养价值。在荞麦中发现的主要生物活性化合物有芦丁、槲皮素、异槲皮素、d-螺肌醇、白藜芦醇和牡荆素,这些化合物是荞麦药理特性的来源。为了恢复荞麦的种植和保护,需要通过探索荞麦的营养、医药和其他具有重要商业价值的替代用途来开展增值研究。考虑到荞麦的多种用途,本综述总结了目前有关荞麦农艺学和营养学意义的知识,以预测其作为农业和功能食品领域未来作物的价值。
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引用次数: 0
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Recent advances in food, nutrition & agriculture
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