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Gastric amyloidosis as an initial presentation of multiple myeloma 胃淀粉样变是多发性骨髓瘤的初始表现。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.012
J. Peng , C. Zhang , X. Tang
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引用次数: 0
Clinical characteristics and treatment of eosinophilic esophagitis in an adult population in Colombia 哥伦比亚成人嗜酸性粒细胞性食管炎的临床特点和治疗。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.003
F. Juliao-Baños , A. Lúquez-Mindiola , A. Gómez-Venegas , V. Parra-Izquierdo , H. Marulanda-Fernández , J. Carvajal-Gutiérrez , B. Arturo-Arias , P. Aponte-Ordoñez , V. Parra-Vargas , J. Toro-Calle , C. Rodríguez-Rubiano , R. Prieto-Ortiz , R. Carmona-Valle , A. Castro-Rodríguez , F. Gil-Parada , J. Castaño-Morales , J. Velásquez-Lopera , J. Donado-Gómez , W. Otero-Regino

Introduction and aim

There is an increase in the incidence and prevalence of eosinophilic esophagitis (EoE) worldwide and data in Latin America are scarce. The aim of our study was to describe the epidemiologic and clinical characteristics of EoE and its treatment, in adult patients in Colombia.

Patients and methods

A descriptive, cross-sectional study was conducted on patients with EoE, with the participation of 16 gastroenterologists from different Colombian cities. Demographic and clinical variables of the patients were evaluated, along with their treatment and complications. EoE severity was calculated utilizing the clinical severity index (CSI).

Results

The study included 152 patients with EoE seen within the time frame of November 2023 and July 2024. A total of 58.6% were men and the mean patient age at diagnosis was 43.3 years (range: 18−79). The time from symptom onset to diagnosis was 32.5 months (median), with an interquartile range (25−75%) of 11.0–79.8 months. A total of 134 (88.2%) patients received treatment with proton pump inhibitors (PPIs), 66 (43.4%) had dietary treatment, 42 (27.6%) received steroids, and 9 (5.9%) underwent endoscopic dilatation. A total of 57.2% of the patients received combination therapy. Histologic remission was achieved in 68.4% of the patients and dysphagia improved in 93.4% of the cases. In relation to the CSI, histologic remission was achieved in 75.6% of the patients with mild disease activity, in 63.9% with moderate activity, and in 50% with severe activity (p = 0.003).

Conclusions

Our results showed there is an important delay in the diagnosis of EoE in Colombia. The most widely used treatment was with PPIs, but more than half the patients had combination therapy. National management guidelines that consider local treatment availability need to be developed.
简介和目的:世界范围内嗜酸性粒细胞性食管炎(EoE)的发病率和患病率都在增加,而拉丁美洲的相关数据很少。本研究的目的是描述哥伦比亚成年患者EoE的流行病学和临床特征及其治疗方法。患者和方法:对来自哥伦比亚不同城市的16名胃肠病学家参与的EoE患者进行了一项描述性横断面研究。评估患者的人口学和临床变量,以及他们的治疗和并发症。利用临床严重程度指数(CSI)计算EoE严重程度。结果:该研究纳入了2023年11月至2024年7月期间就诊的152例EoE患者。58.6%为男性,诊断时平均年龄为43.3岁(范围:18-79岁)。从症状出现到诊断的时间为32.5个月(中位数),四分位数间距(25-75%)为11.0-79.8个月。共有134例(88.2%)患者接受质子泵抑制剂(PPIs)治疗,66例(43.4%)患者接受饮食治疗,42例(27.6%)患者接受类固醇治疗,9例(5.9%)患者接受内镜扩张治疗。共有57.2%的患者接受了联合治疗。68.4%的患者获得组织学缓解,93.4%的患者吞咽困难得到改善。与CSI相关,75.6%的轻度疾病活动期患者、63.9%的中度疾病活动期患者和50%的重度疾病活动期患者实现了组织学缓解(p = 0.003)。结论:我们的研究结果显示,在哥伦比亚有一个重要的延迟诊断EoE。最广泛使用的治疗方法是PPIs,但超过一半的患者采用联合治疗。需要制定考虑到当地治疗可得性的国家管理指南。
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引用次数: 0
“Good clinical practice recommendations for the management of gastroesophageal reflux disease”. The PPI test paradigm 胃食管反流病管理的良好临床规范建议。PPI测试范例。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.025
D. García-Compeán, A.R. Jiménez-Rodríguez
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引用次数: 0
Acute colonic pseudo-obstruction: A case series and literature review 急性结肠假性梗阻:一个病例系列和文献复习。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.023
A. Fuentes-Montalvo, A.L. Ordoñez-Vázquez, J.S. Arenas-Martínez, E. Coss-Adame
Acute colonic pseudo-obstruction (ACPO) is an obstructive phenomenon of functional origin characterized by pain and acute colonic dilatation in the absence of a mechanical cause. It primarily affects patients with several comorbidities, postoperative patients, and/or critically ill patients. The most widely accepted pathophysiologic theory is enteric autonomic dysfunction. Diagnosis must be confirmed through abdominal tomography, ruling out causes of mechanical obstruction and revealing complications, such as ischemia and/or bowel perforation. Treatment is stepped, taking symptom severity, cecal diameter, hemodynamic stability, and/or the presence of complications into account. It is started with conservative measures, and in cases with partial response or refractoriness, there are pharmacologic, endoscopic, and surgical therapeutic options. The aim of this article is to describe four cases of patients diagnosed with ACPO treated at a tertiary care hospital.
急性结肠假性梗阻(ACPO)是一种以疼痛和急性结肠扩张为特征的功能性梗阻现象,没有机械原因。它主要影响有几种合并症的患者、术后患者和/或危重患者。最广泛接受的病理生理学理论是肠自主神经功能障碍。诊断必须通过腹部断层扫描确认,排除机械性梗阻的原因,并揭示并发症,如缺血和/或肠穿孔。治疗是阶梯式的,考虑症状严重程度、盲肠直径、血流动力学稳定性和/或并发症的存在。开始时采取保守措施,在部分缓解或难治性病例中,有药物、内窥镜和手术治疗选择。本文的目的是描述在三级护理医院诊断为ACPO治疗的四例患者。
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引用次数: 0
Double balloon enteroscopy in pediatrics: Evaluation of midgut pathologies at a national medical center 儿科双气囊肠镜检查:国家医疗中心对中肠病理的评估。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.018
A. Meza-Gallegos, R.A. Rodríguez-Izaguirre, M.S. Gallardo-Luna, E.C. Araujo-Gutiérrez, A.R. Castañeda-Ortiz, T.J. Galicia-Gómez

Introduction and aim

Double balloon enteroscopy is used for the diagnosis and treatment of diseases of the small bowel. It is a less invasive means for carrying out a therapeutic intervention, compared with surgical alternatives. Experience with double balloon enteroscopy in pediatrics is in the early stages of development. We believe the performance of this procedure in children has a significant clinical impact on therapeutic decision-making in diseases of the small bowel. Our aim was to evaluate double balloon enteroscopy in children for the diagnosis and treatment of midgut pathologies.

Material and methods

A retrospective, descriptive, and observational study was conducted.

Results

Twenty procedures were performed on patients whose ages ranged from 6 to 17 years, with a mean of 13.3 years. The most frequent indication for doble balloon enteroscopy was gastrointestinal bleeding suspected to originate from the small bowel.
Double balloon enteroscopy resulted in an overall diagnostic yield of 65% and an endoscopic therapeutic yield of 25%. Endoscopic therapy was performed in 4 patients (anastomosis rehabilitation through cutting, sclerosis of vascular lesion with 1.5% polidocanol, polypectomy, biliary stent removal). No patient underwent surgical treatment after double balloon enteroscopy. Therapeutic yield, in general, including endoscopic and medical treatment, was 55%.

Conclusions

We consider double balloon enteroscopy in pediatric patients a feasible procedure, offering good results with minor complications and directly contributing to medical and/or endoscopic decision-making.
简介与目的:双气囊小肠镜用于小肠疾病的诊断和治疗。与外科手术相比,它是一种侵入性较小的治疗干预手段。双气囊小肠镜在儿科的应用尚处于早期发展阶段。我们相信,儿童手术的表现对小肠疾病的治疗决策具有重要的临床影响。我们的目的是评估双气囊小肠镜在儿童中肠病理的诊断和治疗。材料和方法:进行回顾性、描述性和观察性研究。结果:患者年龄6 ~ 17岁,平均13.3岁,共行20例手术。双气囊肠镜检查最常见的适应症是怀疑起源于小肠的胃肠道出血。双气囊肠镜检查的总体诊断率为65%,内镜治疗率为25%。4例患者行内镜治疗(吻合口切开康复、1.5%多卡因硬化血管病变、息肉切除术、胆道支架置换术)。双气囊肠镜检查后无患者行手术治疗。总的来说,包括内窥镜和药物治疗在内的治疗率为55%。结论:我们认为双气囊肠镜检查在儿科患者中是一种可行的手术,效果好,并发症少,并直接有助于医疗和/或内镜决策。
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引用次数: 0
The importance of adequate dietary reporting in nutritional epidemiologic studies 营养流行病学研究中适当饮食报告的重要性。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.028
S.E. Martínez-Vázquez , A. Kammar-García
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引用次数: 0
Upper gastrointestinal involvement secondary to extramedullary plasmacytoma: An unusual presentation in an immunosuppressed patient 继发于髓外浆细胞瘤的上消化道受累:免疫抑制患者的不寻常表现。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.013
S.A. Hernández, A. Chaar, F. Ávila, S. Sambracos
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引用次数: 0
An unusual finding during a colonoscopy: A cockroach! 结肠镜检查中一个不寻常的发现:一只蟑螂!
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.019
J. Rodríguez-Castellot, P. Alonso-Castellano
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引用次数: 0
Erythromelalgia as a paraneoplastic manifestation of colon cancer: A case report 红斑性肢痛作为结肠癌的副肿瘤表现:1例报告。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.020
B.J. Flores Robles, J.A. López-Martín
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引用次数: 0
Considerations about the balanced crystalloid solution recommendation in acute variceal bleeding 急性静脉曲张出血中平衡结晶液推荐的考虑。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.031
O.R. Pérez-Nieto , N. Hernández-Velázquez , J. Beauregard-Mora , M.C. García-Pantoja , J. Reyes-Montufar
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引用次数: 0
期刊
Revista de gastroenterologia de Mexico (English)
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