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Factors associated with mortality in women with decompensated alcohol-related cirrhosis 失代偿性酒精相关性肝硬化妇女死亡率的相关因素
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.016
J.L. Pérez-Hernández , A.D. Santana-Vargas , G. Gutiérrez-Reyes , A. Díaz-Castro , E.J. Morales-Mairena , J.E. Lira-Vera , O. Morales-Gutiérrez , L.S. Juárez Chávez , M.F. Higuera-de-la-Tijera

Introduction and aims

Alcohol-related liver disease is becoming more common worldwide. Recently, alcohol consumption in women has increased significantly, raising the risk of developing alcohol-associated hepatitis, cirrhosis, and hepatocellular carcinoma. Greater susceptibility to alcohol-related liver damage appears to confer a higher mortality and decompensation risk on women. Our study aimed to assess alcohol consumption patterns and mortality rates in female patients with alcohol-related cirrhosis.

Material and methods

We conducted a single-center retrospective cohort study of patients hospitalized for cirrhosis due to chronic alcohol consumption at the Hospital General de Mexico, "Dr. Eduardo Liceaga" between 2018 and 2021. Utilizing the patients’ electronic medical records, alcohol consumption patterns were identified and the survival rate for women and men after their first hospitalization was calculated through the Kaplan-Meier curve.

Results

A final total of 192 electronic medical records (50% women) were included. We classified the patients according to alcohol consumption into a) excessive consumption or b) binge drinking. The median age for the onset of chronic alcohol consumption was higher in women than in men (18 vs. 16.5 years of age; p = 0.0001). The median for alcohol consumption in g/occasion was lower in women than in men (140 vs. 275 in excessive alcohol consumption and 196 vs 320 in binge drinking; p = 0.0001), as was the length of time of chronic alcohol consumption (24.5 vs. 30 years; p = 0.0001)
The mortality rate during the first hospitalization was 32.8% (61.9% for women and 38.9% for men). The mean age for survival was lower for women (33.8 ± 1.6 years of age, 95% CI 30.5–37.1), compared with men (37.0 ± 1.2 years of age, 95% CI 35.4–38.6) (p = 0.002). The factors associated with mortality in the Cox proportional hazards models were women vs men (OR = 4.1, 95% CI 2.1–7.9) and excessive consumption vs binge drinking (OR = 1.9, 95% CI 1.1–3.5).

Conclusions

Alcohol-related mortality is higher in women than in men and is associated with lower alcohol consumption, a shorter period of continued chronic consumption, and an older age at consumption onset.
简介和目的:酒精相关的肝脏疾病在世界范围内变得越来越普遍。最近,女性饮酒量显著增加,增加了患酒精相关肝炎、肝硬化和肝细胞癌的风险。更容易受到酒精相关的肝损伤似乎会给女性带来更高的死亡率和代偿失偿风险。我们的研究旨在评估酒精相关性肝硬化女性患者的饮酒模式和死亡率。材料和方法:我们对2018年至2021年间在墨西哥总医院“Eduardo Liceaga博士”因慢性饮酒而住院的肝硬化患者进行了一项单中心回顾性队列研究。利用患者的电子医疗记录,确定了饮酒模式,并通过Kaplan-Meier曲线计算了首次住院后女性和男性的生存率。结果:最终共纳入192份电子病历,其中女性占50%。我们根据饮酒量将患者分为a)过度饮酒和b)酗酒。女性慢性饮酒发病的中位年龄高于男性(18岁vs. 16.5岁;p 结论:女性酒精相关死亡率高于男性,并且与较低的酒精摄入量、较短的持续慢性饮酒时间和较年长的饮酒发病年龄有关。
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引用次数: 0
Response to the letter to the editor regarding our article: “Dietary characteristics of Mexican patients with irritable bowel syndrome: Is there a distinction from the general population?” 关于我们的文章“墨西哥肠易激综合征患者的饮食特征:与一般人群有区别吗?”
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.029
M. Amieva-Balmori, G.P. Martínez-Perez, J.M. Remes-Troche
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引用次数: 0
Bile duct obstruction following migration of coils placed for managing hepatic artery pseudoaneurysm after biliary stent placement 胆道支架置入术后用于治疗肝动脉假性动脉瘤的线圈移位后胆管梗阻。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.022
R.A. Rincón-Sánchez
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引用次数: 0
Response to Pérez-Nieto et al., “Considerations about the balanced crystalloid solution recommendation in acute variceal bleeding” 对psamurez - nieto等人的“关于急性静脉曲张出血中平衡晶体溶液推荐的考虑”的回应。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.09.025
J.A. Velarde-Ruiz Velasco , E.S. García-Jiménez , J.M. Aldana-Ledesma , F. Higuera-de la Tijera
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引用次数: 0
Esophageal dysmotility and abnormal esophageal acid exposure in idiopathic pulmonary fibrosis patients, candidates for lung transplantation. Experience at an academic center in Northeastern Mexico 特发性肺纤维化患者的食管运动障碍和异常食管酸暴露,肺移植的候选者。在墨西哥东北部的学术中心工作的经历。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.002
G. Torres-Barrera , R.A. Jiménez-Castillo , Y.P. Tolaque-Aldana , J.M. Remes-Troche , H.J. Maldonado-Garza

Introduction and aim

Gastroesophageal reflux disease (GERD) is highly prevalent in patients with idiopathic pulmonary fibrosis (IPF), even in the absence of symptoms. Information on this disease in Latin America is limited. The aim of our study was to determine the prevalence of dysmotility and GERD through high-resolution esophageal manometry (HREM) and 24 h multichannel intraluminal impedance-pH (MII-pH) monitoring in IPF patients, candidates for lung transplantation.

Material and methods

A retrospective, descriptive, observational study was conducted at a tertiary care hospital center. HREM and 24 h MII-pH studies were carried out as part of the protocol for lung transplantation candidates. The manometric and impedance data, including the thoracoabdominal pressure gradient (TAPG), were analyzed.

Results

The study included 37 patients. The mean distal contractile integral was 1530.47 mmHg-s-cm (SD ± 1210.03). Fourteen patients (37.8%) presented with ineffective esophageal motility (IEM). The median percentage of acid exposure time (AET) was 3.20% (range: 1.42-4.90) in the patients with IEM versus 0.50% (range: 0.2-2.90) in the patients with normal esophageal motility (p = 0.022). The mean AET percentage was 3.02% (SD ± 4.17) and the mean number of proximal reflux episodes was 25.88 (SD ± 19.37). Five patients (13.5%) had abnormal AET and a mean TAPG of 14.66 mmHg (SD ± 4.89) versus 17.09 mmHg (SD ± 6.92) in patients with AET < 6% (p = 0.457).

Conclusions

Almost 40% of the patients with IPF, who were candidates for lung transplantation, had IEM. However, the prevalence of GERD was low and not associated with changes in the TAPG.
简介和目的:胃食管反流病(GERD)在特发性肺纤维化(IPF)患者中非常普遍,即使在没有症状的情况下也是如此。拉丁美洲关于这种疾病的信息有限。本研究的目的是通过高分辨率食管测压仪(HREM)和24 h多通道腔内阻抗- ph (MII-pH)监测IPF患者(肺移植候选者)中运动障碍和GERD的患病率。材料和方法:一项回顾性、描述性、观察性研究在一家三级保健医院中心进行。HREM和24 h MII-pH研究作为肺移植候选人方案的一部分进行。分析血压和阻抗数据,包括胸腹压力梯度(TAPG)。结果:纳入37例患者。远端收缩积分平均值为1530.47 mmHg-s-cm (SD ± 1210.03)。14例(37.8%)患者表现为食管运动不良(IEM)。IEM患者酸暴露时间(AET)中位数百分比为3.20%(范围:1.42-4.90),而食管运动正常患者为0.50%(范围:0.2-2.90)(p = 0.022)。平均AET百分比为3.02% (SD ± 4.17),平均近端反流发作次数为25.88次(SD ± 19.37)。5例患者(13.5%)存在AET异常,AET患者的平均TAPG为14.66 mmHg (SD ± 4.89),而AET患者的平均TAPG为17.09 mmHg (SD ± 6.92) 结论:几乎40%的IPF患者(肺移植候选患者)存在IEM。然而,胃食管反流的患病率很低,与TAPG的变化无关。
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引用次数: 0
Intestinal intussusception as a clinical manifestation of primary adenocarcinoma of the terminal ileum 肠套叠作为回肠末端原发性腺癌的临床表现。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.015
F.J. Valentin , C.S. Silva , A. Alfaro , L.E. Zamora-Nava , C. Ortiz
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引用次数: 0
Serum 7αC4 as a pragmatic diagnostic tool for bile acid malabsorption in Mexico: Implications and future directions 血清7αC4作为胆汁酸吸收不良在墨西哥的实用诊断工具:意义和未来方向。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.030
N.K. Rattanapitoon , K. Punnasirimangmee , P. Pholyiam , S.K. Rattanapitoon
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引用次数: 0
Survey of Latin American gastroenterologists, specialists in disorders of gut-brain interaction, on the diagnosis and treatment of irritable bowel syndrome in clinical practice 调查拉丁美洲胃肠病学家,专家肠脑相互作用障碍,肠易激综合征的诊断和治疗在临床实践。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.001
I. Hanna-Jairala , G.A. Puentes-Leal , A.M. Madrid , L. Aguilar-Paiz , J. Suazo-Barahona , J.M. Remes-Troche , E. Coss-Adame , L.M. Bustos-Fernández , L. Solé , M. Gudiño-Zayas , M. Schmulson

Introduction and aim

Even though the guidelines on irritable bowel syndrome (IBS) are similar worldwide, there are differences between countries that can influence management. Our aim was to evaluate the heterogeneity in IBS management in Latin America.

Materials and methods

An internet survey was applied to 97 gastroenterologists, specialists in disorders of gut-brain interaction (DGBI), from 14 Latin American countries, and included 111 questions: 23 on diagnosis and 88 on treatment. An exploratory, descriptive, observational analysis was carried out on general qualitative data, by IBS subtype and by country.

Results

Diagnostic data: 98% of those surveyed utilize the Rome IV criteria; 100% order laboratory tests when there are alarm symptoms; 90% order colonoscopy in patients over 50 years of age; 73% order abdominopelvic CT; 66% order breath tests for SIBO; and 96% order anorectal manometry in IBS-C with symptoms of a defecation disorder. Treatment data: antispasmodics are the most widely prescribed drugs, with differences according to IBS subtype and local availability; 83% indicate a low FODMAP diet; in IBS-D and abdominal distension, more than 90% prescribe rifaximin and/or probiotics, and 81%, cholestyramine; in IBS-C, the most widely prescribed treatments are polyethylene glycol, psyllium, prucalopride, and linaclotide; up to 94% indicate neuromodulators as second-line treatment; and 99% consider indicating psychotherapy in cases of depression.

Conclusions

Even though most of the specialists diagnose and treat IBS in accordance with guidelines, there are differences regarding local availability, and abdominopelvic CT appears to be overused. Knowing how general practitioners and internists manage this entity would be useful for establishing practical guidelines on the diagnosis and treatment of IBS that are adjusted by country.
简介和目的:尽管世界范围内关于肠易激综合征(IBS)的指导方针是相似的,但不同国家之间的差异可能会影响管理。我们的目的是评估拉丁美洲肠易激综合征管理的异质性。材料和方法:对来自14个拉丁美洲国家的97名胃肠病学家、肠脑相互作用紊乱(DGBI)专家进行了网络调查,包括111个问题:23个关于诊断,88个关于治疗。对IBS亚型和国家的一般定性数据进行了探索性、描述性和观察性分析。结果:诊断数据:98%的受访者使用Rome IV标准;当出现报警症状时,100%安排实验室检查;超过50岁的患者90%接受结肠镜检查;73%目骨盆CT;66%的人要求进行SIBO呼吸测试;96%有排便障碍症状的IBS-C患者需要肛肠测压。治疗数据:抗痉挛药物是最广泛使用的处方药,根据IBS亚型和当地可获得性而有所不同;83%建议低FODMAP饮食;对于IBS-D和腹胀,超过90%的患者开利福昔明和/或益生菌,81%的患者开降胆固醇胺;在IBS-C中,最常用的治疗方法是聚乙二醇、车前草、普鲁卡必利和利那氯肽;高达94%的患者将神经调节剂作为二线治疗;99%的人认为抑郁症患者需要心理治疗。结论:尽管大多数专家根据指南诊断和治疗肠易激综合征,但在当地可用性方面存在差异,并且腹部骨盆CT似乎被过度使用。了解全科医生和内科医生如何管理这一实体,将有助于建立根据国家调整的IBS诊断和治疗的实用指南。
{"title":"Survey of Latin American gastroenterologists, specialists in disorders of gut-brain interaction, on the diagnosis and treatment of irritable bowel syndrome in clinical practice","authors":"I. Hanna-Jairala ,&nbsp;G.A. Puentes-Leal ,&nbsp;A.M. Madrid ,&nbsp;L. Aguilar-Paiz ,&nbsp;J. Suazo-Barahona ,&nbsp;J.M. Remes-Troche ,&nbsp;E. Coss-Adame ,&nbsp;L.M. Bustos-Fernández ,&nbsp;L. Solé ,&nbsp;M. Gudiño-Zayas ,&nbsp;M. Schmulson","doi":"10.1016/j.rgmxen.2025.10.001","DOIUrl":"10.1016/j.rgmxen.2025.10.001","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Even though the guidelines on irritable bowel syndrome (IBS) are similar worldwide, there are differences between countries that can influence management. Our aim was to evaluate the heterogeneity in IBS management in Latin America.</div></div><div><h3>Materials and methods</h3><div>An internet survey was applied to 97 gastroenterologists, specialists in disorders of gut-brain interaction (DGBI), from 14 Latin American countries, and included 111 questions: 23 on diagnosis and 88 on treatment. An exploratory, descriptive, observational analysis was carried out on general qualitative data, by IBS subtype and by country.</div></div><div><h3>Results</h3><div>Diagnostic data: 98% of those surveyed utilize the Rome IV criteria; 100% order laboratory tests when there are alarm symptoms; 90% order colonoscopy in patients over 50 years of age; 73% order abdominopelvic CT; 66% order breath tests for SIBO; and 96% order anorectal manometry in IBS-C with symptoms of a defecation disorder. Treatment data: antispasmodics are the most widely prescribed drugs, with differences according to IBS subtype and local availability; 83% indicate a low FODMAP diet; in IBS-D and abdominal distension, more than 90% prescribe rifaximin and/or probiotics, and 81%, cholestyramine; in IBS-C, the most widely prescribed treatments are polyethylene glycol, psyllium, prucalopride, and linaclotide; up to 94% indicate neuromodulators as second-line treatment; and 99% consider indicating psychotherapy in cases of depression.</div></div><div><h3>Conclusions</h3><div>Even though most of the specialists diagnose and treat IBS in accordance with guidelines, there are differences regarding local availability, and abdominopelvic CT appears to be overused. Knowing how general practitioners and internists manage this entity would be useful for establishing practical guidelines on the diagnosis and treatment of IBS that are adjusted by country.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 4","pages":"Pages 530-546"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic treatment of baroliths: A case report 内镜下治疗鼻咽癌1例报告。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.008
N. Reyes Saavedra , C.I. Madinaveitia Sánchez , P. Gálvez Castillejos , L.F. De Giau Triulzi
{"title":"Endoscopic treatment of baroliths: A case report","authors":"N. Reyes Saavedra ,&nbsp;C.I. Madinaveitia Sánchez ,&nbsp;P. Gálvez Castillejos ,&nbsp;L.F. De Giau Triulzi","doi":"10.1016/j.rgmxen.2025.10.008","DOIUrl":"10.1016/j.rgmxen.2025.10.008","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 4","pages":"Pages 615-617"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145373471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating life and death: Successful management of aorto-gastric conduit fistula post-minimally invasive esophagectomy. A case report 导航生与死:微创食管切除术后主动脉胃管瘘的成功处理。一份病例报告。
Pub Date : 2025-10-01 DOI: 10.1016/j.rgmxen.2025.10.007
Z.S. Khanzada , T. Asim , M. Asim , M. Waqas
{"title":"Navigating life and death: Successful management of aorto-gastric conduit fistula post-minimally invasive esophagectomy. A case report","authors":"Z.S. Khanzada ,&nbsp;T. Asim ,&nbsp;M. Asim ,&nbsp;M. Waqas","doi":"10.1016/j.rgmxen.2025.10.007","DOIUrl":"10.1016/j.rgmxen.2025.10.007","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 4","pages":"Pages 620-622"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145373447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Revista de gastroenterologia de Mexico (English)
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