首页 > 最新文献

Rhode Island medical journal (2013)最新文献

英文 中文
Positive Culture of Atypical Mycobacterium Avium Following Revision Total Knee Arthroplasty. 翻修全膝关节置换术后非典型分枝杆菌培养阳性。
Pub Date : 2024-05-02
Jonathan Liu, Jacob Laperche, Marguerite Neill, Derek Jenkins

Case: We report a rare case of mycobacterial periprosthetic joint infection (PJI) after primary total knee arthroplasty 14 years earlier. Progressive knee pain over three years with a negative PJI infectious workup led to revision total knee arthroplasty. A surprising result was isolation of Mycobacterium avium from tissue cultures taken at time of revision surgery. After six months of antibiotic treatment, the patient is alive with well- functioning pain-free TKA at over one-year follow-up.

Conclusion: Periprosthetic joint infection can present acutely or chronically years following total knee arthroplasty. Depending on the infecting organism, patients can present with sepsis, or a more indolent slower course that mimics aseptic loosening. In the absence of positive pre-operative labs and cultures, and based on the Musculoskeletal Infection Society (MSIS) criteria, aseptic loosening is a diagnosis of exclusion. An atypical infectious organism should be considered a possible cause and may require specialized cultures of operative specimens.

病例:我们报告了一例罕见病例,患者在 14 年前接受初次全膝关节置换术后发生了霉菌性假体周围关节感染(PJI)。膝关节疼痛持续了三年,PJI感染检查结果为阴性,因此患者接受了翻修全膝关节置换术。一个令人惊讶的结果是,在翻修手术时从组织培养物中分离出了分枝杆菌。经过6个月的抗生素治疗后,该患者在一年多的随访中恢复了健康,并进行了功能良好的无痛TKA手术:结论:人工关节周围感染可在全膝关节置换术后数年内急性或慢性发作。根据感染病原体的不同,患者可能出现败血症,也可能出现类似无菌性松动的缓慢病程。如果术前化验和培养结果未呈阳性,根据肌肉骨骼感染协会(MSIS)的标准,无菌性松动是排除性诊断。非典型感染性有机体应被视为可能的病因,可能需要对手术标本进行专门培养。
{"title":"Positive Culture of Atypical Mycobacterium Avium Following Revision Total Knee Arthroplasty.","authors":"Jonathan Liu, Jacob Laperche, Marguerite Neill, Derek Jenkins","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Case: </strong>We report a rare case of mycobacterial periprosthetic joint infection (PJI) after primary total knee arthroplasty 14 years earlier. Progressive knee pain over three years with a negative PJI infectious workup led to revision total knee arthroplasty. A surprising result was isolation of Mycobacterium avium from tissue cultures taken at time of revision surgery. After six months of antibiotic treatment, the patient is alive with well- functioning pain-free TKA at over one-year follow-up.</p><p><strong>Conclusion: </strong>Periprosthetic joint infection can present acutely or chronically years following total knee arthroplasty. Depending on the infecting organism, patients can present with sepsis, or a more indolent slower course that mimics aseptic loosening. In the absence of positive pre-operative labs and cultures, and based on the Musculoskeletal Infection Society (MSIS) criteria, aseptic loosening is a diagnosis of exclusion. An atypical infectious organism should be considered a possible cause and may require specialized cultures of operative specimens.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Taking the Pulse of the Nursing Home Industry in Rhode Island. 把握罗德岛州养老院行业的脉搏。
Pub Date : 2024-05-02
Robert B Hackey, Colleen Dorrian, Meghan Levesque

Introduction: Nursing home facilities in Rhode Island face unprecedented challenges today. Most facilities find themselves in a difficult financial position with thin - or negative - operating margins. In addition, Rhode Island enacted new minimum staffing regulations for nursing homes in 2021. Facilities that fail to meet the new staffing requirements would incur significant financial penalties. The persistent shortage of direct care staff, however, limits administrators' ability to hire the workers needed to meet the required staffing levels.

Methods: We conducted an online survey of nursing home administrators at all of the licensed nursing facilities in Rhode Island over 30 days from September to October 2023. We received responses from 53 out of 77 nursing home administrators, for an overall response rate of 69%.

Results: A majority of respondents reported numerous vacancies for clinical staff at their facilities. Most administrators felt that it was difficult to hire new staff, despite a variety of financial incentives to recruit workers. As a result, nursing homes were unable to comply with Rhode Island's new minimum staffing requirements.

Conclusion: Nursing homes in Rhode Island continue to experience a chronic staffing shortage. Furthermore, since a majority of nursing homes in Rhode Island have a negative operating margin, enforcing the state's minimum staffing requirements would impose significant financial hardship on the state's nursing facilities.

导言:如今,罗德岛州的养老院设施面临着前所未有的挑战。大多数机构发现自己的财务状况十分困难,经营利润微薄,甚至为负数。此外,罗德岛州于 2021 年颁布了新的养老院最低人员配置规定。达不到新的人员配备要求的养老机构将受到严厉的经济处罚。然而,直接护理人员的持续短缺限制了管理者雇用所需员工以达到规定人员配备水平的能力:我们在 2023 年 9 月至 10 月的 30 天内对罗得岛州所有持证护理机构的养老院管理人员进行了在线调查。我们收到了 77 位养老院管理者中 53 位的回复,总回复率为 69%:结果:大多数受访者表示,他们的机构有大量临床人员空缺。大多数管理者认为,尽管为招聘员工提供了各种经济激励措施,但仍很难招聘到新员工。因此,养老院无法达到罗德岛州新的最低人员配置要求:结论:罗得岛州的养老院仍然长期面临人手不足的问题。此外,由于罗得岛州大多数养老院的经营利润率为负数,执行该州的最低人员编制要求将给该州的养老机构带来巨大的经济困难。
{"title":"Taking the Pulse of the Nursing Home Industry in Rhode Island.","authors":"Robert B Hackey, Colleen Dorrian, Meghan Levesque","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Nursing home facilities in Rhode Island face unprecedented challenges today. Most facilities find themselves in a difficult financial position with thin - or negative - operating margins. In addition, Rhode Island enacted new minimum staffing regulations for nursing homes in 2021. Facilities that fail to meet the new staffing requirements would incur significant financial penalties. The persistent shortage of direct care staff, however, limits administrators' ability to hire the workers needed to meet the required staffing levels.</p><p><strong>Methods: </strong>We conducted an online survey of nursing home administrators at all of the licensed nursing facilities in Rhode Island over 30 days from September to October 2023. We received responses from 53 out of 77 nursing home administrators, for an overall response rate of 69%.</p><p><strong>Results: </strong>A majority of respondents reported numerous vacancies for clinical staff at their facilities. Most administrators felt that it was difficult to hire new staff, despite a variety of financial incentives to recruit workers. As a result, nursing homes were unable to comply with Rhode Island's new minimum staffing requirements.</p><p><strong>Conclusion: </strong>Nursing homes in Rhode Island continue to experience a chronic staffing shortage. Furthermore, since a majority of nursing homes in Rhode Island have a negative operating margin, enforcing the state's minimum staffing requirements would impose significant financial hardship on the state's nursing facilities.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating the Effectiveness of COVID-19 Mitigation Policy in Rhode Island. 估算罗德岛 COVID-19 减缓政策的效果。
Pub Date : 2024-05-02
John P Fulton, Thomas A Trikalinos, Jonah Popp, Stephanie Pollen, Dana Barclay, Mark Freeman, Maria Messick
{"title":"Estimating the Effectiveness of COVID-19 Mitigation Policy in Rhode Island.","authors":"John P Fulton, Thomas A Trikalinos, Jonah Popp, Stephanie Pollen, Dana Barclay, Mark Freeman, Maria Messick","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"55-59"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Consequence of an Electrical-Burn Injury: Atrial Fibrillation. 电烧伤的后果:心房颤动
Pub Date : 2024-05-02
Anita Knopov, Giovanna Deluca, Tareq Kheirbek, Nicholas J Musisca

Cardiac arrhythmias following electrocution injuries can accompany high-voltage or high- intensity currents. Contributing factors to electrical hazard are the type of current, voltage, resistance, and duration of contact and pathway through the body. It is important to monitor for delayed arrhythmias in patients with an electrical injury. We describe a case of a 52-year-old man who presented after an electrical shock injury while grabbing a 5,000-voltage wire at work. In this case report, we discuss the presentation, management, and follow-up recommendations for this type of injury.

触电伤害后的心律失常可能伴随着高压或高强度电流。造成电击危险的因素包括电流类型、电压、电阻、接触时间和通过身体的路径。监测电击伤患者的延迟性心律失常非常重要。我们描述了一例 52 岁男子的病例,他在工作中抓住一根 5000 伏的电线时受到电击伤害。在本病例报告中,我们讨论了此类损伤的表现、处理方法和后续建议。
{"title":"A Consequence of an Electrical-Burn Injury: Atrial Fibrillation.","authors":"Anita Knopov, Giovanna Deluca, Tareq Kheirbek, Nicholas J Musisca","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cardiac arrhythmias following electrocution injuries can accompany high-voltage or high- intensity currents. Contributing factors to electrical hazard are the type of current, voltage, resistance, and duration of contact and pathway through the body. It is important to monitor for delayed arrhythmias in patients with an electrical injury. We describe a case of a 52-year-old man who presented after an electrical shock injury while grabbing a 5,000-voltage wire at work. In this case report, we discuss the presentation, management, and follow-up recommendations for this type of injury.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"18-20"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ebstein's Anomaly of the Tricuspid Valve. 三尖瓣埃布斯坦氏异常。
Pub Date : 2024-05-02
Beatriz Rizkallah Alves, Carolina Saldanha Neves Horta Lima, Somwail Rasla
{"title":"Ebstein's Anomaly of the Tricuspid Valve.","authors":"Beatriz Rizkallah Alves, Carolina Saldanha Neves Horta Lima, Somwail Rasla","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"21-24"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refractory Hypoglycemia Due to Sulfonylurea Contamination of Illicit Opioid Medications. 非法阿片类药物磺酰脲类污染导致的难治性低血糖症。
Pub Date : 2024-05-02
Jeffrey R Savarino, Robert Mokszycki, Robert Tubbs, Rachel S Wightman

Illicit drug supply adulteration can heighten the risk for adverse health outcomes. Sulfonylurea medications are widely used in the treatment of diabetes mellitus (DM). Unintentional or intentional overdose of sulfonylureas can cause refractory hypoglycemia. This case report describes a 62-year-old male patient who presented to the emergency department (ED) after being found on the ground with signs of mild trauma. He was noted to be persistently hypoglycemic despite boluses of intravenous dextrose, a dextrose infusion, and oral nutrition. The patient did report purchase and oral ingestion of pills sold as oxycodone and that the pill shape and color were different from his usual supply. The patient was empirically treated with octreotide resulting in normalization of his serum glucose. Testing demonstrated a serum glipizide concentration six times the reporting range. This case represents unintentional sulfonylurea exposure in the setting of non-prescribed oxycodone use, resulting in hypoglycemia refractory to intravenous dextrose and oral nutrition. Octreotide is an additional potential treatment for this condition. As in this case, ingestion of street drugs may present a potential source of sulfonylurea exposure. Opioid contamination with sulfonylureas has not been widely reported in the literature and knowledge about this potential exposure is important for the prompt recognition and treatment of these patients by emergency physicians.

非法药物供应掺假会增加不良健康后果的风险。磺脲类药物被广泛用于治疗糖尿病(DM)。无意或有意过量服用磺脲类药物可导致难治性低血糖。本病例报告描述了一名 62 岁的男性患者,他被发现倒在地上并伴有轻微外伤症状,随后被送往急诊科(ED)。尽管静脉注射了葡萄糖栓剂、葡萄糖输液和口服营养液,但他仍持续低血糖。患者确实报告购买并口服了以羟考酮名义出售的药片,而且药片的形状和颜色与他平时服用的药片不同。患者接受了奥曲肽的经验性治疗,结果血糖恢复正常。检测显示血清格列吡嗪浓度是报告范围的六倍。本病例表明,患者在非处方使用羟考酮的情况下无意中接触了磺脲类药物,导致静脉注射葡萄糖和口服营养剂无效的低血糖症。奥曲肽是治疗这种情况的另一种潜在方法。与本病例一样,摄入街头毒品也可能成为磺脲类药物的潜在暴露源。文献中尚未广泛报道过阿片类药物与磺脲类药物的污染,了解这种潜在的接触对于急诊医生及时识别和治疗这些患者非常重要。
{"title":"Refractory Hypoglycemia Due to Sulfonylurea Contamination of Illicit Opioid Medications.","authors":"Jeffrey R Savarino, Robert Mokszycki, Robert Tubbs, Rachel S Wightman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Illicit drug supply adulteration can heighten the risk for adverse health outcomes. Sulfonylurea medications are widely used in the treatment of diabetes mellitus (DM). Unintentional or intentional overdose of sulfonylureas can cause refractory hypoglycemia. This case report describes a 62-year-old male patient who presented to the emergency department (ED) after being found on the ground with signs of mild trauma. He was noted to be persistently hypoglycemic despite boluses of intravenous dextrose, a dextrose infusion, and oral nutrition. The patient did report purchase and oral ingestion of pills sold as oxycodone and that the pill shape and color were different from his usual supply. The patient was empirically treated with octreotide resulting in normalization of his serum glucose. Testing demonstrated a serum glipizide concentration six times the reporting range. This case represents unintentional sulfonylurea exposure in the setting of non-prescribed oxycodone use, resulting in hypoglycemia refractory to intravenous dextrose and oral nutrition. Octreotide is an additional potential treatment for this condition. As in this case, ingestion of street drugs may present a potential source of sulfonylurea exposure. Opioid contamination with sulfonylureas has not been widely reported in the literature and knowledge about this potential exposure is important for the prompt recognition and treatment of these patients by emergency physicians.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"11-13"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urothelial Carcinoma: Epidemiology and Imaging-Based Review. 尿路上皮癌:流行病学和影像学回顾。
Pub Date : 2024-05-02
Ashwin C Reddy, Joey Z Gu, Brandon H Koo, Victoria Fruh, Alessandra J Sax

Bladder cancer is the 6th most common malignancy in the United States, with urothelial carcinomas comprising over 95% of cases of bladder cancer, and commands a significant disease burden in Rhode Island. Imaging studies can provide valuable diagnostic information for urothelial carcinomas at initial presentation and are routinely used for noninvasive staging, treatment response monitoring, and post-treatment surveillance. This review aims to discuss and highlight three imaging modalities: ultrasonography, computed tomography, and magnetic resonance imaging, with particular focus on the notable features and appearance of urothelial carcinoma on each modality and their relative utility throughout the disease course. A general overview of disease epidemiology and treatment practices is also provided.

膀胱癌是美国第六大最常见的恶性肿瘤,其中尿路上皮癌占膀胱癌病例的 95% 以上,在罗德岛州造成了巨大的疾病负担。影像学研究可在尿路上皮癌初次发病时提供有价值的诊断信息,并被常规用于无创分期、治疗反应监测和治疗后监测。本综述旨在讨论并重点介绍三种成像方式:超声波检查、计算机断层扫描和磁共振成像,尤其侧重于每种成像方式在尿路上皮癌的显著特征和外观,以及它们在整个病程中的相对效用。此外,还提供了疾病流行病学和治疗方法的总体概述。
{"title":"Urothelial Carcinoma: Epidemiology and Imaging-Based Review.","authors":"Ashwin C Reddy, Joey Z Gu, Brandon H Koo, Victoria Fruh, Alessandra J Sax","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bladder cancer is the 6th most common malignancy in the United States, with urothelial carcinomas comprising over 95% of cases of bladder cancer, and commands a significant disease burden in Rhode Island. Imaging studies can provide valuable diagnostic information for urothelial carcinomas at initial presentation and are routinely used for noninvasive staging, treatment response monitoring, and post-treatment surveillance. This review aims to discuss and highlight three imaging modalities: ultrasonography, computed tomography, and magnetic resonance imaging, with particular focus on the notable features and appearance of urothelial carcinoma on each modality and their relative utility throughout the disease course. A general overview of disease epidemiology and treatment practices is also provided.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"26-32"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Common Peroneal Nerve and Tarsal Tunnel Release Surgery in an Adolescent Male with Hunter Syndrome: Illustrative Case. 一名患有亨特综合征的青少年男性的腓总神经和跗骨隧道松解手术:示例病例。
Pub Date : 2024-05-02
Elijah M Persad-Paisley, Belinda Shao, Vinay Rao, Loree K Kalliainen

Background: Children with Hunter syndrome have a high prevalence of nerve compression syndromes given the buildup of glycosaminoglycans in the tendon sheaths and soft tissue structures. These are often comorbid with orthopedic conditions given joint and tendon contractures due to the same pathology. While carpal tunnel syndrome and surgical treatment has been well-reported in this population, the literature on lower extremity nerve compression syndromes and their treatment in Hunter syndrome is sparse.

Observations: We report the case of a 13-year-old male with a history of Hunter syndrome who presented with toe-walking and tenderness over the peroneal and tarsal tunnel areas. He underwent bilateral common peroneal nerve and tarsal tunnel releases, with findings of severe nerve compression and hypertrophied soft tissue structures demonstrating fibromuscular scarring on pathology. Post-operatively, the patient's family reported subjective improvement in lower extremity mobility and plantar flexion.

Lessons: In this case, peroneal and tarsal nerve compression were diagnosed clinically and treated effectively with surgical release and postoperative ankle casting. Given the wide differential of common comorbid orthopedic conditions in Hunter syndrome and the lack of validated electrodiagnostic normative values in this population, the history and physical examination and consideration of nerve compression syndromes are tantamount for successful workup and treatment of gait abnormalities in the child with Hunter syndrome.

背景:由于腱鞘和软组织结构中糖胺聚糖的堆积,亨特综合征患儿的神经压迫综合征发病率很高。由于同样的病理原因导致关节和肌腱挛缩,这些症状通常会合并骨科疾病。虽然腕管综合征和手术治疗在这一人群中已有大量报道,但有关亨特综合征的下肢神经压迫综合征及其治疗的文献却很少:我们报告了一例有亨特综合征病史的 13 岁男性病例,他出现了脚趾行走以及腓骨和跗骨隧道区域的压痛。他接受了双侧腓总神经和跗骨隧道松解术,术后发现神经严重受压,软组织结构肥大,病理显示为纤维肌性瘢痕。术后,患者家属表示下肢活动能力和跖屈能力得到了主观改善:在本病例中,腓总神经和跗神经压迫经临床确诊,并通过手术松解和术后踝关节石膏固定得到了有效治疗。鉴于亨特综合征常见合并骨科疾病的广泛差异,以及缺乏该人群的有效电诊断标准值,病史和体格检查以及神经压迫综合征的考虑对于亨特综合征患儿步态异常的成功检查和治疗至关重要。
{"title":"Common Peroneal Nerve and Tarsal Tunnel Release Surgery in an Adolescent Male with Hunter Syndrome: Illustrative Case.","authors":"Elijah M Persad-Paisley, Belinda Shao, Vinay Rao, Loree K Kalliainen","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Children with Hunter syndrome have a high prevalence of nerve compression syndromes given the buildup of glycosaminoglycans in the tendon sheaths and soft tissue structures. These are often comorbid with orthopedic conditions given joint and tendon contractures due to the same pathology. While carpal tunnel syndrome and surgical treatment has been well-reported in this population, the literature on lower extremity nerve compression syndromes and their treatment in Hunter syndrome is sparse.</p><p><strong>Observations: </strong>We report the case of a 13-year-old male with a history of Hunter syndrome who presented with toe-walking and tenderness over the peroneal and tarsal tunnel areas. He underwent bilateral common peroneal nerve and tarsal tunnel releases, with findings of severe nerve compression and hypertrophied soft tissue structures demonstrating fibromuscular scarring on pathology. Post-operatively, the patient's family reported subjective improvement in lower extremity mobility and plantar flexion.</p><p><strong>Lessons: </strong>In this case, peroneal and tarsal nerve compression were diagnosed clinically and treated effectively with surgical release and postoperative ankle casting. Given the wide differential of common comorbid orthopedic conditions in Hunter syndrome and the lack of validated electrodiagnostic normative values in this population, the history and physical examination and consideration of nerve compression syndromes are tantamount for successful workup and treatment of gait abnormalities in the child with Hunter syndrome.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"14-17"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the Trends of Tramadol Utilization in the Medicare Part D Population in Rhode Island. 评估罗德岛州医疗保险 D 部分人群使用曲马多的趋势。
Pub Date : 2024-05-02
Eric P Borrelli

Objective: To assess the trends in tramadol dispensing among Medicare Part D patients in Rhode Island.

Methods: An analysis was conducted of the Medicare Part D Provider Utilization and Payment Data Public Use File for the years 2013-2021. Chi squared tests were conducted to assess statistical significance of annual changes in proportions.

Results: Following tramadol becoming a controlled substance in 2014, the number of dispensed tramadol prescriptions and patients with a tramadol prescription decreased every subsequent year through 2021 (prescriptions: 42,157 to 33,026; patients: 12,654 to 9,653). The percentage of opioid prescriptions that were tramadol increased from 16.32% in 2013 to 21.19% in 2020.

Conclusion: Tramadol utilization has been decreasing among the Medicare Part D population in Rhode Island while the percentage of opioid dispensings that were tramadol have been increasing. Future studies are needed to assess whether patients utilizing tramadol are at a higher risk for adverse outcomes.

目的:评估罗德岛州医疗保险 D 部分患者曲马多的配药趋势:评估罗德岛州医疗保险 D 部分患者曲马多的配药趋势:对 2013-2021 年的医疗保险 D 部分提供者使用和支付数据公共使用文件进行了分析。结果:在曲马多成为管制药物后,罗德岛州的医疗保险 D 部分患者中,曲马多的用药量增加了:曲马多于2014年成为受管制药物后,曲马多处方的配发数量和持有曲马多处方的患者数量在随后的2021年逐年下降(处方:42157张降至33026张;患者:12654人降至9653人)。曲马多占阿片类药物处方的比例从2013年的16.32%增至2020年的21.19%:在罗德岛州的医疗保险 D 部分人群中,曲马多的使用率一直在下降,而阿片类药物中曲马多的配药比例却在上升。今后需要开展研究,评估使用曲马多的患者是否会面临更高的不良后果风险。
{"title":"Assessing the Trends of Tramadol Utilization in the Medicare Part D Population in Rhode Island.","authors":"Eric P Borrelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To assess the trends in tramadol dispensing among Medicare Part D patients in Rhode Island.</p><p><strong>Methods: </strong>An analysis was conducted of the Medicare Part D Provider Utilization and Payment Data Public Use File for the years 2013-2021. Chi squared tests were conducted to assess statistical significance of annual changes in proportions.</p><p><strong>Results: </strong>Following tramadol becoming a controlled substance in 2014, the number of dispensed tramadol prescriptions and patients with a tramadol prescription decreased every subsequent year through 2021 (prescriptions: 42,157 to 33,026; patients: 12,654 to 9,653). The percentage of opioid prescriptions that were tramadol increased from 16.32% in 2013 to 21.19% in 2020.</p><p><strong>Conclusion: </strong>Tramadol utilization has been decreasing among the Medicare Part D population in Rhode Island while the percentage of opioid dispensings that were tramadol have been increasing. Future studies are needed to assess whether patients utilizing tramadol are at a higher risk for adverse outcomes.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"33-37"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cholangiocarcinoma: Epidemiology and Imaging-Based Review. 胆管癌:流行病学和影像学回顾。
Pub Date : 2024-05-02
Simon Kidanemariam, Joey Gu, Jessica H Yoon, Jothika V Challapalli, Victoria Fruh, Alessandra J Sax

Cholangiocarcinoma (CCA) is a rare cancer of the bile duct epithelium, and in the last few decades its incidence rate has been increasing. It is associated with a high mortality rate due to late diagnosis and its aggressive nature. Many risk factors have been identified; some are more common in certain regions than others. CCA can be classified according to its anatomical location or macroscopic growth pattern, the latter being most helpful for imaging interpretation. Clinical features can vary from obstructive-like symptoms to nonspecific symptoms, such as weight loss and malaise. Imaging, specifically MRI/MRCP, is crucial in diagnosing CCA, staging, and treatment planning. Surgery with chemotherapy is the mainstay treatment option, and other palliative treatment options exist for those who have unresectable disease.

胆管癌(Colangiocarcinoma,CCA)是一种罕见的胆管上皮癌,在过去几十年中,其发病率不断上升。由于诊断较晚且具有侵袭性,它的死亡率很高。目前已发现许多风险因素,其中一些因素在某些地区比其他地区更为常见。CCA 可根据其解剖位置或宏观生长模式进行分类,后者对影像学解释最有帮助。临床特征可从阻塞性症状到非特异性症状(如体重减轻和精神萎靡)不等。影像学检查,尤其是 MRI/MRCP,对 CCA 的诊断、分期和治疗计划至关重要。手术加化疗是主要的治疗方案,对于无法切除的疾病,也有其他姑息治疗方案。
{"title":"Cholangiocarcinoma: Epidemiology and Imaging-Based Review.","authors":"Simon Kidanemariam, Joey Gu, Jessica H Yoon, Jothika V Challapalli, Victoria Fruh, Alessandra J Sax","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cholangiocarcinoma (CCA) is a rare cancer of the bile duct epithelium, and in the last few decades its incidence rate has been increasing. It is associated with a high mortality rate due to late diagnosis and its aggressive nature. Many risk factors have been identified; some are more common in certain regions than others. CCA can be classified according to its anatomical location or macroscopic growth pattern, the latter being most helpful for imaging interpretation. Clinical features can vary from obstructive-like symptoms to nonspecific symptoms, such as weight loss and malaise. Imaging, specifically MRI/MRCP, is crucial in diagnosing CCA, staging, and treatment planning. Surgery with chemotherapy is the mainstay treatment option, and other palliative treatment options exist for those who have unresectable disease.</p>","PeriodicalId":74738,"journal":{"name":"Rhode Island medical journal (2013)","volume":"107 5","pages":"43-48"},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Rhode Island medical journal (2013)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1