Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-64-71
E. O. Belyanina
Percutaneous laser coagulation (selective photothermolysis) is currently the «gold standard» for the treatment of «port-wine stains». However, complete removal of the vascular lesion is rarely possible, and in 20 % of cases there is resistance to laser attack. The article presents clinical cases of «port-wine stains» treatment in two patients. On the basis of own experience and literature data the analysis of treatment results, side effects of lasers application was carried out, and also alternative perspective methods of treatment were considered.
{"title":"Features of laser coagulation of «port-wine stains» (cases from practice)","authors":"E. O. Belyanina","doi":"10.21518/1995-1477-2019-1-2-64-71","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-64-71","url":null,"abstract":"Percutaneous laser coagulation (selective photothermolysis) is currently the «gold standard» for the treatment of «port-wine stains». However, complete removal of the vascular lesion is rarely possible, and in 20 % of cases there is resistance to laser attack. The article presents clinical cases of «port-wine stains» treatment in two patients. On the basis of own experience and literature data the analysis of treatment results, side effects of lasers application was carried out, and also alternative perspective methods of treatment were considered.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81810139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-146-152
S. Katorkin, S. Bystrov, O. Lisin, A. Rozanova, A. Bezborodov
Objective. Evaluate the efficacy of the treatment of purulent skin and soft tissue wounds using modern interactive dressings and conventional wound care dressings. Material and methods. The study included 160 patients, who were treated at the outpatient department of the Clinic of the SamGMU for the period from September 2018 to January 2019 after an autopsy, necrosectomy and drainage of purulent foci in the surgical hospital. Group I (n = 82) included patients, who applied Sorbalgon® interactive dressing (Paul Hartmann, Germany) during the first phase of the wound healing and Branolind® N atraumatic mesh dressing (Paul Hartmann, Germany) during the second phase of the wound healing for topical treatment of wounds in the postoperative period. Patients of Group II (n = 78) applied ointment dressings using Levomekol ointment during the first phase of the wound healing and Methyluracil ointment during the second phase of the wound healing. Patients in both groups received the same broad spectrum antibacterial therapy. In Group I, the dressings were applied once per 2 days, in Group II the dressings were applied on a daily basis. The researchers studied the following indicators: the nature of the wound discharge; the presence of edema and hyperemia of tissues; timing of the wound defect cleansing; temperature and leukocyte reactions of the body; crops on microflora and sensitivity to antibiotic therapy. Results. The study showed more pronounced dynamics of the temperature reaction normalization, reduction of the local inflammatory reaction and the leukocytosis level in patients of Group I. The wound cleansing from pus and fibrin, the development of granulation tissue on Day 5 were reported in 87.8% of patients of Group I and in 35.9% of patients of Group II, on Day 10 in 100% and 88.5% of patients, respectively. Conclusion. The use of Sorbalgon® and Branolind® N dressings improves the results of treatment of patients with purulent soft tissues pathology and reduces the risk for secondary infection, and improves the quality of life due to increase of interval between the dressings.
{"title":"Evaluation of the efficacy of modern wound care dressings in the complex treatment of purulent wounds","authors":"S. Katorkin, S. Bystrov, O. Lisin, A. Rozanova, A. Bezborodov","doi":"10.21518/1995-1477-2019-1-2-146-152","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-146-152","url":null,"abstract":"Objective. Evaluate the efficacy of the treatment of purulent skin and soft tissue wounds using modern interactive dressings and conventional wound care dressings. Material and methods. The study included 160 patients, who were treated at the outpatient department of the Clinic of the SamGMU for the period from September 2018 to January 2019 after an autopsy, necrosectomy and drainage of purulent foci in the surgical hospital. Group I (n = 82) included patients, who applied Sorbalgon® interactive dressing (Paul Hartmann, Germany) during the first phase of the wound healing and Branolind® N atraumatic mesh dressing (Paul Hartmann, Germany) during the second phase of the wound healing for topical treatment of wounds in the postoperative period. Patients of Group II (n = 78) applied ointment dressings using Levomekol ointment during the first phase of the wound healing and Methyluracil ointment during the second phase of the wound healing. Patients in both groups received the same broad spectrum antibacterial therapy. In Group I, the dressings were applied once per 2 days, in Group II the dressings were applied on a daily basis. The researchers studied the following indicators: the nature of the wound discharge; the presence of edema and hyperemia of tissues; timing of the wound defect cleansing; temperature and leukocyte reactions of the body; crops on microflora and sensitivity to antibiotic therapy. Results. The study showed more pronounced dynamics of the temperature reaction normalization, reduction of the local inflammatory reaction and the leukocytosis level in patients of Group I. The wound cleansing from pus and fibrin, the development of granulation tissue on Day 5 were reported in 87.8% of patients of Group I and in 35.9% of patients of Group II, on Day 10 in 100% and 88.5% of patients, respectively. Conclusion. The use of Sorbalgon® and Branolind® N dressings improves the results of treatment of patients with purulent soft tissues pathology and reduces the risk for secondary infection, and improves the quality of life due to increase of interval between the dressings.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78182958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-38-44
S. Katorkin, M. A. Melnikov, P. F. Kravtsov
Aim of the study. To evaluate the clinical efficacy of sulodexide in the daily dosage of 500 LSU in patients with chronic lower limb vein diseases of clinical classes C1-C3 according to CEAP. Patients and methods. This study included 35 patients with chronic C1-C3 CEAP lower limb vein disease who took 500 LSU of Sulodexide for 90 days. In order to evaluate the effectiveness of the treatment we used: a questionnaire to assess the quality of patient’s life with chronic venous insufficiency CIVIQ 20; visually – analogue scale of pain assessment VAS; clinical scale of venous diseases VCSS severity assessment; measuring the circumference of the limbs on the hip and shin. Results of the study. The study was completed by 32 patients. As a result of the performed treatment the convulsive syndrome in calf muscles completely regressed, though on the first visit it was registered in 22,4 % of patients (p = 0,0481), the frequency of complaints about severity and fatigue in the lower limbs at static loads decreased significantly from 28,1 % to 9,6 % (p = 0,2414). The circumference of the femur in the middle third of the limb decreased from 53.7 cm to 51.1 cm (p<0.05), in the middle third of the tibia from 36.8 cm to 33.8 cm (p<0.05) and in the lower third of the tibia from 23.4 cm to 21.5 cm (p<0.05). VAS pain syndrome decreased from 35.36 ± 24.71 mm to 16.44 ± 17.07 mm (p = 0.0005). The global CIVIQ 20 quality of life index increased by 25.3 % compared to the initial parameters (p = 0.0001), the VCSS index decreased from 5.93 ± 1.79 points to 4.79 ± 2.01 points (p = 0.0002). Conclusion. Sulodexide, causing a pronounced clinical effect, is an effective and pathogenetically justified drug for the treatment of initial forms of chronic lower limb vein disease.
研究的目的。目的:评价舒洛地特每日剂量500 LSU治疗临床分类C1-C3的慢性下肢静脉疾病患者的临床疗效。患者和方法。本研究纳入35例慢性C1-C3 CEAP下肢静脉疾病患者，他们服用500 LSU的舒洛地特90天。为了评价治疗的有效性，我们采用问卷调查的方式评估慢性静脉功能不全患者的生活质量(civiq20);视觉模拟疼痛评估量表;静脉疾病VCSS严重程度评定临床量表测量臀部和小腿的四肢周长。研究结果。该研究由32名患者完成。由于进行了治疗，小腿肌肉痉挛综合征完全消退，尽管在第一次就诊时有22.4%的患者登记(p = 0,0481)，但在静态负荷下下肢严重和疲劳的主诉频率从28.1%显著下降到9.6% (p = 0,2414)。下肢中1 / 3股骨周长由53.7 cm减小至51.1 cm (p<0.05)，胫骨中1 / 3股骨周长由36.8 cm减小至33.8 cm (p<0.05)，胫骨下1 / 3股骨周长由23.4 cm减小至21.5 cm (p<0.05)。VAS疼痛综合征由35.36±24.71 mm降至16.44±17.07 mm (p = 0.0005)。与初始参数相比，全球CIVIQ 20生活质量指数提高了25.3% (p = 0.0001)， VCSS指数从5.93±1.79降至4.79±2.01 (p = 0.0002)。结论。舒洛地特临床疗效显著，是治疗慢性下肢静脉疾病的一种有效且病理合理的药物。
{"title":"Sulodexide efficacy in the treatment of patients with chronic lower limb vein diseases of C1-C3 clinical classes according to CEAP","authors":"S. Katorkin, M. A. Melnikov, P. F. Kravtsov","doi":"10.21518/1995-1477-2019-1-2-38-44","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-38-44","url":null,"abstract":"Aim of the study. To evaluate the clinical efficacy of sulodexide in the daily dosage of 500 LSU in patients with chronic lower limb vein diseases of clinical classes C1-C3 according to CEAP. Patients and methods. This study included 35 patients with chronic C1-C3 CEAP lower limb vein disease who took 500 LSU of Sulodexide for 90 days. In order to evaluate the effectiveness of the treatment we used: a questionnaire to assess the quality of patient’s life with chronic venous insufficiency CIVIQ 20; visually – analogue scale of pain assessment VAS; clinical scale of venous diseases VCSS severity assessment; measuring the circumference of the limbs on the hip and shin. Results of the study. The study was completed by 32 patients. As a result of the performed treatment the convulsive syndrome in calf muscles completely regressed, though on the first visit it was registered in 22,4 % of patients (p = 0,0481), the frequency of complaints about severity and fatigue in the lower limbs at static loads decreased significantly from 28,1 % to 9,6 % (p = 0,2414). The circumference of the femur in the middle third of the limb decreased from 53.7 cm to 51.1 cm (p<0.05), in the middle third of the tibia from 36.8 cm to 33.8 cm (p<0.05) and in the lower third of the tibia from 23.4 cm to 21.5 cm (p<0.05). VAS pain syndrome decreased from 35.36 ± 24.71 mm to 16.44 ± 17.07 mm (p = 0.0005). The global CIVIQ 20 quality of life index increased by 25.3 % compared to the initial parameters (p = 0.0001), the VCSS index decreased from 5.93 ± 1.79 points to 4.79 ± 2.01 points (p = 0.0002). Conclusion. Sulodexide, causing a pronounced clinical effect, is an effective and pathogenetically justified drug for the treatment of initial forms of chronic lower limb vein disease.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"134 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86317927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-72-79
K. A. Korejba, A. R. Minabutdinov, L. M. Tueshev, A. R. Nuretdinov, P. Lukin
One of the main problems of modern surgery is treatment of trophic skin and soft tissues defects due to the ambiguity of the pathogenesis, tendency to recurrence, deterioration in the patients’ quality of life, complexity and duration of treatment, large economic costs of treatment and rehabilitation. The article describes an algorithm for outpatient treatment of patients with trophic skin and soft tissues defects in diabetic foot syndrome. Debridement the wound from necrosis, purulent-fibrinous pellicles, wound biofilms is produced by a chemical necrectomy. A method of closing the wound defects by the means of high-tech biomaterials based on collagen type 1 is described.
{"title":"Diabetic foot syndrome. Replacement for inpatient treatment technique based on the fast track surgery","authors":"K. A. Korejba, A. R. Minabutdinov, L. M. Tueshev, A. R. Nuretdinov, P. Lukin","doi":"10.21518/1995-1477-2019-1-2-72-79","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-72-79","url":null,"abstract":"One of the main problems of modern surgery is treatment of trophic skin and soft tissues defects due to the ambiguity of the pathogenesis, tendency to recurrence, deterioration in the patients’ quality of life, complexity and duration of treatment, large economic costs of treatment and rehabilitation. The article describes an algorithm for outpatient treatment of patients with trophic skin and soft tissues defects in diabetic foot syndrome. Debridement the wound from necrosis, purulent-fibrinous pellicles, wound biofilms is produced by a chemical necrectomy. A method of closing the wound defects by the means of high-tech biomaterials based on collagen type 1 is described.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73994587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-93-98
M. S. Svetlova
The problem of treating pain in patients with diseases of the musculoskeletal system and its injuries is highly relevant, which is associated with the high prevalence of this pathology. The basis of pain is always inflammation. In order to influence the inflammatory process as quickly as possible, therapy should be comprehensive, safe, and as effective as possible. In recent years, complex bioregulatory preparation Traumeel C, produced as an ointment and gel, has been widely used in the treatment of diseases of the musculoskeletal system and injuries. The article presents data on the mechanism of action of the drug, as well as the results of studies that examined the efficacy and safety of Traumeel C ointment and gel for diseases of the musculoskeletal system and injuries of the musculoskeletal system.
{"title":"Integrated approach to treatment of pain syndrome in musculoskeletal system injuries and disorders","authors":"M. S. Svetlova","doi":"10.21518/1995-1477-2019-1-2-93-98","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-93-98","url":null,"abstract":"The problem of treating pain in patients with diseases of the musculoskeletal system and its injuries is highly relevant, which is associated with the high prevalence of this pathology. The basis of pain is always inflammation. In order to influence the inflammatory process as quickly as possible, therapy should be comprehensive, safe, and as effective as possible. In recent years, complex bioregulatory preparation Traumeel C, produced as an ointment and gel, has been widely used in the treatment of diseases of the musculoskeletal system and injuries. The article presents data on the mechanism of action of the drug, as well as the results of studies that examined the efficacy and safety of Traumeel C ointment and gel for diseases of the musculoskeletal system and injuries of the musculoskeletal system.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84758373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-45-51
V. Bogachev, K. A. Kaperiz
In the review article various indications for the use of adjustable inelastic compression bandage circaid are considered, and an actual clinical example of its successful application is given. The authors draw a conclusion about the universality of circaid bandage and the expediency of its wide use in real clinical practice.
{"title":"Several practical aspects of the use of adjustable inelastic compression bandages (AICB)","authors":"V. Bogachev, K. A. Kaperiz","doi":"10.21518/1995-1477-2019-1-2-45-51","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-45-51","url":null,"abstract":"In the review article various indications for the use of adjustable inelastic compression bandage circaid are considered, and an actual clinical example of its successful application is given. The authors draw a conclusion about the universality of circaid bandage and the expediency of its wide use in real clinical practice.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80409756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-112-117
E. A. Zagryadsky
The article is devoted to the topical issue of increasing prevalence of hemorrhoid disease in modern society. It provides the detailed description of pathogenesis of the disease and clinical manifestations of hemorrhoids. Particular attention is paid to diagnostic tests and procedures that help physicians to diagnose a disease and choose a therapy, including diet, improvement of bowel habits and function, normalization of the blood flow rate in haemorrhoidal plexuses by prescription of phlebotropic drugs. Among them, the combined topical drugs that have a thrombolytic, anti-inflammatory and hemostatic effect hold pride of place in the treatment of hemorrhoid disease.
{"title":"Modern treatment of acute hemorrhoids","authors":"E. A. Zagryadsky","doi":"10.21518/1995-1477-2019-1-2-112-117","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-112-117","url":null,"abstract":"The article is devoted to the topical issue of increasing prevalence of hemorrhoid disease in modern society. It provides the detailed description of pathogenesis of the disease and clinical manifestations of hemorrhoids. Particular attention is paid to diagnostic tests and procedures that help physicians to diagnose a disease and choose a therapy, including diet, improvement of bowel habits and function, normalization of the blood flow rate in haemorrhoidal plexuses by prescription of phlebotropic drugs. Among them, the combined topical drugs that have a thrombolytic, anti-inflammatory and hemostatic effect hold pride of place in the treatment of hemorrhoid disease.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86672993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-87-92
M. V. Zhuchkov, U. V. Zhuchkova, S. V. Tarasenko
The article presents the results of the clinical study on the assessment of the preventive clinical effectiveness of the topical combined antibacterial drug bacitracin/neomycin in the prevention of infection during surgical intervention. The study included 112 patients whose average age was 42.4+7.4 years. Patients were divided into groups according to the risk of infection of the surgical area (SSI) according to the criteria of D.C. Classen et al. and into subgroups according to whether standard antiseptic therapy or topical antibacterial therapy with bacitracin/neomycin was used in the postoperative period. The study demonstrated high preventive efficacy of the topical drug bacitracin/neomycin in the prevention of various clinical forms of SSI and, probably, in the prevention of seromas of postoperative wounds.
{"title":"The possibility of using a topical combined antibacterial agent in the prevention of infection during surgical intervention","authors":"M. V. Zhuchkov, U. V. Zhuchkova, S. V. Tarasenko","doi":"10.21518/1995-1477-2019-1-2-87-92","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-87-92","url":null,"abstract":"The article presents the results of the clinical study on the assessment of the preventive clinical effectiveness of the topical combined antibacterial drug bacitracin/neomycin in the prevention of infection during surgical intervention. The study included 112 patients whose average age was 42.4+7.4 years. Patients were divided into groups according to the risk of infection of the surgical area (SSI) according to the criteria of D.C. Classen et al. and into subgroups according to whether standard antiseptic therapy or topical antibacterial therapy with bacitracin/neomycin was used in the postoperative period. The study demonstrated high preventive efficacy of the topical drug bacitracin/neomycin in the prevention of various clinical forms of SSI and, probably, in the prevention of seromas of postoperative wounds.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89735610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.21518/1995-1477-2019-1-2-124-130
G. Knorring
Acute and chronic hemorrhoids and coexisting conditions remain an important medical problem at the intersection of medical specialties. Among the proposed approaches to therapy is the use of immunomodulating agents, which allows to ensure the influence on several pathogenetic mechanisms of development and progression of the disease. Ointments containing bacterial cultural suspension of E. coli (BCS) as an active component have a solid experience in clinical practice and a strong evidence base, including meta-analysis of multicenter randomized trials.
{"title":"Justification and experience of using ointments with immunomodulating properties in hemorrhoids and anal fissures","authors":"G. Knorring","doi":"10.21518/1995-1477-2019-1-2-124-130","DOIUrl":"https://doi.org/10.21518/1995-1477-2019-1-2-124-130","url":null,"abstract":"Acute and chronic hemorrhoids and coexisting conditions remain an important medical problem at the intersection of medical specialties. Among the proposed approaches to therapy is the use of immunomodulating agents, which allows to ensure the influence on several pathogenetic mechanisms of development and progression of the disease. Ointments containing bacterial cultural suspension of E. coli (BCS) as an active component have a solid experience in clinical practice and a strong evidence base, including meta-analysis of multicenter randomized trials.","PeriodicalId":7496,"journal":{"name":"Ambulatory surgery: hospital-replacing technologies","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79226746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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