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Research & Innovation Abstracts 研究,摘要创新
Pub Date : 2023-10-06 DOI: 10.38192/1.8.3.1
Roshelle Ramkisson
BAPIO Institute for Health Research
BAPIO健康研究所
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引用次数: 0
The Importance of an Innovation Culture in the NHS 创新文化在NHS中的重要性
Pub Date : 2023-07-31 DOI: 10.38192/1.8.2.12
D. Behan
Keynote on 'Global trends in healthcare sustainability Digital Revolution in Health Care
关于“医疗保健可持续发展的全球趋势”的主题演讲
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引用次数: 0
Reducing Risks in Healthcare by Prioritising Workforce Well-being 通过优先考虑员工福利来降低医疗保健风险
Pub Date : 2023-07-15 DOI: 10.38192/1.8.2.5
S. Dodds, Joydeep Grover, A. Mahmood, Triya Chakravorty
Considering risks to healthcare covers a wide variety of topics. This cover’s an extensive area such as sustainability, including funding; planning, long-term policy development; and trends, including the emergence of publicly funded versus private healthcare or a hybrid offering. Other topics include workforce planning, involving the consideration of self-sufficiency versus importing; examination of delivery modes of hospitals versus community; and final consideration of balancing affordability with expectation and need. As part of a consideration of risk is an anticipation of what dangers may arise. This can be borne out of existing knowledge of known threats, which remain ongoing, trends and predicted risk patterns, and unexpected risks.
考虑医疗保健风险涵盖了各种各样的主题。这个覆盖范围很广,比如可持续性,包括资金;规划、长期政策制定;以及趋势,包括公共资助与私人医疗保健或混合服务的出现。其他主题包括劳动力规划,涉及考虑自给自足与进口;医院与社区分娩模式比较最后要考虑的是平衡负担能力与期望和需求。作为风险考虑的一部分,是对可能出现的危险的预测。这可以从已知威胁的现有知识(这些威胁仍在进行)、趋势和预测的风险模式以及意外风险中得到证实。
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引用次数: 0
Mild In Vitro Fertilisation 轻度体外受精
Pub Date : 2023-07-15 DOI: 10.38192/1.8.2.4
Beth Farrer, Helen Nesbitt, L. Osborne, Camilla Stanley, G. Nargund
The case for making healthcare more sustainable is becoming increasingly urgent. Medical professionals understand the need to reduce the cost and environmental impact of our work. We also see that being creative in how we plan treatment pathways and communicate with patients can allow us to work sustainably in terms of the resources required, and in tandem, deliver real benefits for patients. Approaches that deliver ‘prevention rather than cure’ and keep medical intervention as minimally invasive as possible are often better for patients, as well as better for the environment.These concepts are particularly pertinent in the field of reproductive and women’s health, where CREATE Fertility specialise in adopting an approach that is friendly and safe. With natural and mild IVF treatment, delivered with lower doses of drugs, CREATE is able to offer women treatment that reduces risks, side effects and the burden of IVF and supports healthier outcomes for mother and baby, while maintaining outcomes.That philosophy of putting patients first and finding a more efficient way to work is at the heart of the foundation of CREATE’s ABC IVF. In the UK, and around the world, access to fertility treatment is not fair or equal. For many women and couples, cost is a major barrier and one that can stop them building the family they want. In the UK, availability of NHStreatment is variable around the country. At the time of its launch, ABC IVF was the UK’s lowest cost IVF provider, offering a lifeline to thousands of patients who would not otherwise have been able to access treatment.In women’s healthcare, alongside education, innovation and research is key, yet in the UK it is acknowledged that historically there has been a ‘male as default’ approach that has affected research and clinical trials 1 . Professor Nargund is committed to helping to work towards the UN’s sustainable development goals three (health and wellbeing), five (gender inequality), ten (reduced inequality) and thirteen (climate action) with s push to provide affordable, accessible, effective and safe fertility treatment, delivered sustainably. The work is far from over and Professor Nargund and her team remain committed to improving the outlook for women’s healthcare.
使医疗保健更具可持续性的理由正变得越来越紧迫。医疗专业人员明白需要减少我们工作的成本和对环境的影响。我们还看到,在规划治疗途径和与患者沟通的方式上具有创造性,可以使我们在所需资源方面可持续地工作,并同时为患者带来真正的好处。提供“预防而不是治疗”并使医疗干预尽可能微创的方法往往对患者更好,对环境也更好。这些概念特别适用于生殖和妇女健康领域,CREATE Fertility专门在这一领域采用友好和安全的方法。通过自然和温和的体外受精治疗,以较低剂量的药物提供,CREATE能够为妇女提供治疗,降低风险,副作用和体外受精的负担,并支持母亲和婴儿更健康的结果,同时保持结果。把病人放在第一位,寻找更有效的工作方式,这是CREATE ABC试管婴儿的核心理念。在英国和世界各地,获得生育治疗是不公平或不平等的。对许多女性和夫妇来说,成本是一个主要障碍,可以阻止她们建立自己想要的家庭。在英国,nhtreatment的可用性在全国范围内是不同的。在成立之初,ABC试管婴儿是英国成本最低的试管婴儿提供商,为成千上万本来无法获得治疗的患者提供了一条生命线。在女性医疗保健中,除了教育之外,创新和研究也是关键,但在英国,人们承认,历史上一直存在一种“男性默认”的方法,这种方法影响了研究和临床试验。纳冈德教授致力于帮助实现联合国可持续发展目标3(健康和福祉)、5(性别不平等)、10(减少不平等)和13(气候行动),并推动提供负担得起、可获得、有效和安全的生育治疗,并以可持续的方式提供。这项工作远未结束,纳尔冈德教授和她的团队仍致力于改善女性医疗保健的前景。
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引用次数: 0
Introduction to Artificial Intelligence Prediction for Healthcare 医疗保健人工智能预测导论
Pub Date : 2023-07-15 DOI: 10.38192/1.8.2.7
Anindya Chakravorty
Artificial intelligence (AI) aims to mimic human cognitive functions. It is bringing a paradigm shift to healthcare, powered by the increasing availability of healthcare data and rapid progress of analytics techniques.1 AI can be applied to various types of healthcare data (structured and unstructured). Popular AI techniques include machine learning methods for structured data, such as the classical support vector machine and neural network, modern deep learning, and natural language processing for unstructured data. Major disease areas that use AI tools include cancer, neurology and cardiology. 
人工智能(AI)旨在模仿人类的认知功能。它正在为医疗保健带来范式转变,这得益于医疗保健数据的日益可用性和分析技术的快速进步人工智能可以应用于各种类型的医疗保健数据(结构化和非结构化)。流行的人工智能技术包括结构化数据的机器学习方法,如经典的支持向量机和神经网络,现代深度学习和非结构化数据的自然语言处理。使用人工智能工具的主要疾病领域包括癌症、神经病学和心脏病学。
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引用次数: 0
Mutually Beneficial Immigration is Key to Global Healthcare Sustainability 互惠互利的移民是全球医疗保健可持续发展的关键
Pub Date : 2023-07-15 DOI: 10.38192/1.8.2.6
Ramesh Mehta, I. Chakravorty
It is estimated that this unequal world we live in, will need 80 million health workers to meet the demands of the global population by the end of the decade, double the number in 2013.1,2 The population distribution across the globe is skewed (Fig 1) with high densities in Africa, South Asia and South America which characteristically remains mismatched to their gross domestic product and net wealth, which is enjoyed by nations with the least population densities (Fig 2). Healthcare provision within geo-politically separated nation-states continues to be driven by local social, political and economic factors. Therefore, the adage of ‘no size fits all’ is applicable. No two countries have the same healthcare system, anywhere in the world, we know today. Yet the desire to achieve ‘Health for All’ should be universal.3 Implementation of the fundamental principle that health promotion and prevention must be prioritised before the resource intense diagnosis and management of maladies, is believed to be the only way to achieve any form of sustainability in healthcare provision.
据估计,到本十年结束时,我们生活在这个不平等的世界中,将需要8000万卫生工作者来满足全球人口的需求,这一数字是2013年的两倍,3.1,2全球人口分布是倾斜的(图1),非洲、南亚和南美洲的人口密度很高,其特点是与其国内生产总值和净财富仍然不匹配。在地缘政治上分开的民族国家内,医疗保健的提供继续受到当地社会、政治和经济因素的推动。因此,“没有放之四海而皆准”的格言是适用的。我们今天知道,在世界上任何地方,没有两个国家拥有相同的医疗体系。然而,实现“人人享有卫生保健”的愿望应该是普遍的人们认为,在资源密集的疾病诊断和管理之前,必须优先考虑促进和预防健康这一基本原则的执行,是在提供保健方面实现任何形式的可持续性的唯一途径。
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引用次数: 0
Understanding Polycystic Ovary Syndrome (PCOS): 了解多囊卵巢综合征(PCOS):
Pub Date : 2023-07-15 DOI: 10.38192/1.8.2.3
Triya Chakravorty
Polycystic ovary syndrome (PCOS) is the commonest metabolic and endocrine disorder that affects women of reproductive age. It is characterised by irregular menstruation, hyperandrogenism and polycystic ovarian morphology. While significant progress has been made in understanding PCOS, several research questions remain. For instance, there is a need for further investigation into the aetiology of PCOS, including the role of genetic and environmental factors, to aid in earlier diagnosis and treatment. Additionally, while some therapies have been effective in managing the symptoms of PCOS, their long-term efficacy and safety remain uncertain. There is a need to better understand the long-term health consequences of PCOS, particularly regarding cardiovascular disease and cancer risk.                                                                        Early diagnosis, lifestyle modifications, and appropriate medical interventions can help to reduce the risk of complications and improve the overall health outcomes of women with PCOS. Looking forward, there is a need for a multidisciplinary approach to studying PCOS, including collaborations between researchers, healthcare providers, and patient advocacy groups. This may involve developing new tools and technologies for diagnosis and treatment and exploring novel interventions and therapies.There is a growing recognition of the importance of PCOS as a significant health issue affecting millions of women worldwide, and continued research efforts will be critical for improving diagnosis, treatment, and long-term outcomes for those affected by the condition.
多囊卵巢综合征(PCOS)是影响育龄妇女的最常见的代谢和内分泌疾病。它的特点是月经不规律,雄激素过多和多囊卵巢形态。虽然在了解多囊卵巢综合征方面取得了重大进展,但仍存在一些研究问题。例如,有必要进一步调查多囊卵巢综合征的病因,包括遗传和环境因素的作用,以帮助早期诊断和治疗。此外,虽然一些治疗方法对控制多囊卵巢综合征的症状有效,但其长期疗效和安全性仍不确定。需要更好地理解PCOS的长期健康后果,尤其是心血管疾病和癌症的风险 .                                                                        早期诊断、改变生活方式和适当的医疗干预有助于减少并发症的风险,改善多囊卵巢综合征妇女的整体健康状况。展望未来,需要多学科方法来研究多囊卵巢综合征,包括研究人员、医疗保健提供者和患者倡导团体之间的合作。这可能涉及开发用于诊断和治疗的新工具和技术,以及探索新的干预措施和疗法。人们越来越认识到多囊卵巢综合征是影响全世界数百万妇女的重要健康问题,持续的研究工作对于改善多囊卵巢综合征患者的诊断、治疗和长期预后至关重要。
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引用次数: 3
Metacognition for Every Clinician 每个临床医生的元认知
Pub Date : 2023-07-15 DOI: 10.38192/1.8.2.9
U. Shiralkar
A call to action, Surgical Metacognition: Smarter Decision-making for Surgeons challenges surgeons to understand the processes that underpin decision-making and performance, and how we can use this new knowledge to improve a surgeon's performance both in and outside the operating theatre. Decision-making is a core professional activity for surgeons of all levels. It is a distinct high-level skill that is closely associated with the quality of surgical outcomes, patient satisfaction, teamwork, and a surgeon's well-being. Yet it has so far been woefully neglected in surgical training and professional development, with an assumption that these skills develop on their own and cannot be taught or improved. This is an unfortunate and costly oversight that it is time we redress. But how are good decisions and expertise made? And how can we as a profession improve our thinking to optimize our decision-making and train expertise? The answer lies not only in gaining more knowledge and experience, which although essential for good decision-making, do not address the fact that so few of us understand the process itself, let alone how to optimize and teach it. The first step, and focus of this book, is understating 'metacognition'; 'thinking about thinking, ' to improve self-awareness, critical thinking and how we make decisions. The profound developments of psychology and decision-science are now well established and have been successfully incorporated into other high-stakes professions such as senior business management, the military and aviation, to significantly improve both professional and personal outcomes. That surgery has yet to implement this knowledge is like a race car driver using a car with technology that is decades old, ignoring developments that would significantly increase performance. It is time for surgery to embrace this knowledge; to advance and modernize the profession with sharper critical thinking and teaching. With many real-world surgical examples, Surgical Metacognition: Smarter Decision-making for Surgeons reviews the psychological understanding of decisions and decision-making from recent decades of research, giving us the tools to improve how we think and teach this fundamental skill of expertise.
《外科元认知:外科医生更明智的决策》一书呼吁采取行动,挑战外科医生理解决策和表现的基础过程,以及我们如何利用这些新知识提高外科医生在手术室内外的表现。决策是各级外科医生的核心专业活动。这是一项独特的高级技能,与手术结果的质量、患者满意度、团队合作和外科医生的健康密切相关。然而,到目前为止,它在外科培训和专业发展中被可悲地忽视了,人们认为这些技能是自己发展的,不能教授或提高。这是一个不幸和代价高昂的疏忽,现在是我们纠正的时候了。但是,好的决策和专业知识是如何产生的呢?作为一名专业人士,我们该如何改进我们的思维,优化我们的决策和培训专业知识?答案不仅在于获得更多的知识和经验,尽管这对良好的决策至关重要,但并没有解决这样一个事实,即我们中很少有人了解这个过程本身,更不用说如何优化和教授它了。第一步,也是本书的重点,是理解“元认知”;“思考思考”,提高自我意识、批判性思维和决策能力。心理学和决策科学的深刻发展现在已经确立,并已成功地纳入其他高风险的职业,如高级企业管理,军事和航空,以显着提高专业和个人的成果。外科手术尚未实现这一知识,就像赛车手使用几十年前的技术,忽视了可以显著提高性能的发展。现在是外科医生接受这一知识的时候了;以更敏锐的批判性思维和教学来推进和现代化专业。《外科元认知:外科医生更聪明的决策》一书通过许多现实世界的手术案例,回顾了近几十年研究中对决策和决策的心理学理解,为我们提供了改进思维方式和教授这一基本专业技能的工具。
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引用次数: 0
Frugal Surgical Innovations are the Need of the Hour 节约型外科创新是当前的需要
Pub Date : 2023-07-15 DOI: 10.38192/1.8.2.8
D. Sharma
Innovation is defined by the dictionaries as “a new idea, device, or method; or the act or process of introducing new ideas, devices, or methods.” However, Surgical Innovation (SI) is more difficult to define. Common narratives include why-where-how-what-who as well as novelty, degree of change, safety, ethical standards, level of impact and peer acceptance. [1, 2] We have proposed a simpler, more egalitarian and ‘inclusive’ definition: “a SI is ‘any’ new surgical idea which improves patient welfare by solving an existing problem; and which like a three-legged stool is balanced by the three legs which represent surgical-precision, surgical-wisdom and patient-safety”. [3] Frugal Surgical Innovations (FSIs) are low-cost surgical innovations which are designed for economic reasons. These are all about ‘doing more and better with less for more people’. [4] FSIs make up for their lack in sophistication or complexity in affordability, without scrimping on safety or effectiveness. The three constructs of FSIs are: affordability, adaptability and accessibility. [5] The philosophy of FSIs originates from grassroots, resource-constrained settings (RCS), where most abundant of all-natural resources — human ingenuity — is used to optimize limited resources to solve problems. [6] Clinically meaningful inclusive research can be performed ‘only’ by surgeons working in RCS; as ‘only’ they understand the difficulties and nuances of various problems and can provide simple affordable solutions for their patients. [7]
词典对创新的定义是“一种新的想法、装置或方法;或引入新思想、新装置或新方法的行为或过程。”然而,外科创新(SI)更难定义。常见的叙述包括为什么在哪里,怎么做,谁,以及新颖性,变化程度,安全性,道德标准,影响程度和同伴接受程度。[1,2]我们提出了一个更简单、更平等、更“包容”的定义:“SI是通过解决现有问题来改善患者福利的‘任何’新的外科理念;它就像一个三脚凳,由三条腿平衡,代表手术的精确,手术的智慧和病人的安全。”[3]节约型手术创新(FSIs)是一种低成本的手术创新,是出于经济原因而设计的。这些都是关于“用更少的钱为更多的人做更多更好的事情”。b[4]金融稳定机构弥补了它们在可负担性和复杂性方面的不足,而不会在安全性和有效性方面打折扣。金融服务设施的三个结构是:可负担性、适应性和可及性。[5]金融服务机构的理念源于草根、资源受限的环境(RCS),在那里,最丰富的自然资源——人类的聪明才智——被用来优化有限的资源来解决问题。[6]临床有意义的包容性研究只能由在RCS工作的外科医生进行;作为“唯一”,他们了解各种问题的困难和细微差别,并能为患者提供简单、负担得起的解决方案。[7]
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引用次数: 0
An Audit of Hypophosphatemia after Intravenous Iron Therapy 静脉铁治疗后低磷血症的审计
Pub Date : 2023-06-04 DOI: 10.38192/1.8.1.13
M. Shahani, P. Thiagarajah, I. Chakravorty
BackgroundDue to the gastrointestinal side-effects of oral iron supplementation in patients with iron deficiency anaemia, which impairs tolerance - many acute medical and haematology day units provide intravenous iron replacement therapy as day cases. Hypophosphatemia is a frequent side effect following intravenous iron administration, which can persist for weeks or months, is under-recognised in clinical practice and can lead to patients presenting with typical features to the emergency departments.AimWe designed an audit to measure the incidence of symptomatic hypophosphatemia after intravenous iron therapy to develop monitoring, prevention, and treatment strategy in a secondary care hospital setting.MethodsWe audited a convenience sample of consecutive patients who attended an acute day-care assessment unit for intravenous (IV) iron infusion (ferric carboxymaltose). All patients had serum phosphate levels checked after IV iron infusion at different intervals, from 1- 6 weeks. The cohort was divided into two groups based on the occurrence of hypophosphataemia - early (1-3 weeks) and late (>3-6 weeks).ResultsWe included 35 patients referred from primary care, gastroenterology, gynaecology, and acute internal medicine. 19 (55%) developed hypophosphatemia after receiving a single IV iron infusion and almost 100% after more than one dose. Hypophosphatemia in some patients lasted up to 12 weeks.ConclusionHypophosphatemia was frequent after a single dose and almost universal after multiple doses of IV Iron, which can persist for many weeks. Clinicians prescribing ferric carboxymaltose (Ferinject®) should be aware of hypophosphataemia, which could be mild, moderate, or severe and can last for months.
背景:由于口服补铁对缺铁性贫血患者的胃肠道副作用,会损害耐受性,许多急性医学和血液学日间单位提供静脉补铁治疗作为日间病例。低磷血症是静脉给铁后常见的副作用,可持续数周或数月,在临床实践中未得到充分认识,并可导致患者以典型特征向急诊室就诊。AimWe设计了一项审计来测量静脉铁治疗后症状性低磷血症的发生率,以制定二级护理医院环境中的监测、预防和治疗策略。方法:我们审核了在急性日托评估单位连续接受静脉(IV)铁输注(三羧基麦芽糖铁)的患者的方便样本。所有患者在静脉输铁后1- 6周的不同时间间隔检查血清磷酸盐水平。根据低磷血症的发生情况将该队列分为早期(1-3周)和晚期(>3-6周)两组。结果我们纳入了来自初级保健、胃肠病学、妇科和急症内科的35例转诊患者。19例(55%)在接受单次静脉铁输注后出现低磷血症,在接受一次以上剂量输注后几乎100%。一些患者的低磷血症持续时间长达12周。结论单次给药后低磷血症发生率高,多次给药后低磷血症发生率高,可持续数周。开具羧基麦芽糖铁(Ferinject®)处方的临床医生应注意低磷血症,可分为轻度、中度或重度,并可持续数月。
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引用次数: 0
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The Homoeopathic physician
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