Pub Date : 2026-03-17DOI: 10.1186/s13195-026-02000-z
Jetske van der Schaar, Leonie N C Visser, Eva C A Asscher, Yolande A L Pijnenburg, Christa M de Geus, Wiesje M van der Flier, Annelien L Bredenoord, Mariette A van den Hoven, Ellen M A Smets, Sven J van der Lee
{"title":"Impact of diagnostic genetic testing for familial dementia: experiences of patients and relatives.","authors":"Jetske van der Schaar, Leonie N C Visser, Eva C A Asscher, Yolande A L Pijnenburg, Christa M de Geus, Wiesje M van der Flier, Annelien L Bredenoord, Mariette A van den Hoven, Ellen M A Smets, Sven J van der Lee","doi":"10.1186/s13195-026-02000-z","DOIUrl":"https://doi.org/10.1186/s13195-026-02000-z","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147472355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-12DOI: 10.1186/s13195-026-02011-w
Shayan Mostafaei, Daniel Wikström Shemer, Jonathan K L Mak, Ida K Karlsson, Sara Hägg
{"title":"Improved polygenic risk prediction for alzheimer's disease and related dementias using deep learning: age and APOE-stratified analysis.","authors":"Shayan Mostafaei, Daniel Wikström Shemer, Jonathan K L Mak, Ida K Karlsson, Sara Hägg","doi":"10.1186/s13195-026-02011-w","DOIUrl":"https://doi.org/10.1186/s13195-026-02011-w","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147442294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-12DOI: 10.1186/s13195-026-01986-w
Junjie Wu, Benjamin B Risk, Taylor A James, Nicholas T Seyfried, David W Loring, Felicia C Goldstein, Allan I Levey, James J Lah, Deqiang Qiu
{"title":"Non-linear associations of amyloid-β with resting-state functional networks and their cognitive relevance in a large community-based cohort of cognitively normal older adults.","authors":"Junjie Wu, Benjamin B Risk, Taylor A James, Nicholas T Seyfried, David W Loring, Felicia C Goldstein, Allan I Levey, James J Lah, Deqiang Qiu","doi":"10.1186/s13195-026-01986-w","DOIUrl":"10.1186/s13195-026-01986-w","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147442304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-12DOI: 10.1186/s13195-026-02002-x
Youn Huh, Ga Eun Nam, Kyungdo Han, Jin-Hyung Jung, Bong Seong Kim, Dohee Lee, Hyun Jin Park, Mun Young Yoo, Seo Yeon Yoon, Sung Hoon Kang, Chi Kyung Kim, Seon Mee Kim, Hye Soon Park
{"title":"Body mass index levels and changes before and after dementia diagnosis and risk of all-cause mortality: a nationwide cohort study.","authors":"Youn Huh, Ga Eun Nam, Kyungdo Han, Jin-Hyung Jung, Bong Seong Kim, Dohee Lee, Hyun Jin Park, Mun Young Yoo, Seo Yeon Yoon, Sung Hoon Kang, Chi Kyung Kim, Seon Mee Kim, Hye Soon Park","doi":"10.1186/s13195-026-02002-x","DOIUrl":"https://doi.org/10.1186/s13195-026-02002-x","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147442333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-09DOI: 10.1186/s13195-026-02001-y
Andre Mueller, Aleksandar Jovalekic, Marianne Chapleau, Julius Seidel, Maria Ritter, Eva-Maria Bickel, Nadine Kiessling, Emer MacSweeney, Andrew W Stephens, Norman Koglin
{"title":"In-vitro interaction studies between the amyloid PET tracer florbetaben and the amyloid-beta targeting antibodies lecanemab and donanemab on AD brain samples reveal no interferences.","authors":"Andre Mueller, Aleksandar Jovalekic, Marianne Chapleau, Julius Seidel, Maria Ritter, Eva-Maria Bickel, Nadine Kiessling, Emer MacSweeney, Andrew W Stephens, Norman Koglin","doi":"10.1186/s13195-026-02001-y","DOIUrl":"10.1186/s13195-026-02001-y","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":"18 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12969857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-05DOI: 10.1186/s13195-026-01998-6
Claire J Cadwallader, Pedro Pinheiro-Chagas, Rowan Saloner, Laura Fenton, Anna M VandeBunte, May Lin, Albert Pham, Coty Chen, Valentina E Diaz, Molly Olzinski, Sophia Licata, Lana Callies, Carina Lo, Jessica Buxton, Yann Cobigo, Gil Rabinovici, Joel H Kramer, Kaitlin B Casaletto, Emily W Paolillo
{"title":"The active ingredients: physical activity features linked to healthy brain aging.","authors":"Claire J Cadwallader, Pedro Pinheiro-Chagas, Rowan Saloner, Laura Fenton, Anna M VandeBunte, May Lin, Albert Pham, Coty Chen, Valentina E Diaz, Molly Olzinski, Sophia Licata, Lana Callies, Carina Lo, Jessica Buxton, Yann Cobigo, Gil Rabinovici, Joel H Kramer, Kaitlin B Casaletto, Emily W Paolillo","doi":"10.1186/s13195-026-01998-6","DOIUrl":"https://doi.org/10.1186/s13195-026-01998-6","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147363754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-05DOI: 10.1186/s13195-026-02008-5
Yi Jayne Tan, Raziyeh Mohammadi, Seyed Ehsan Saffari, Nicole Isabella Tan, Louis Ss Lim, Shermine Hl Low, Louis Cs Tan, Hui Jin Chiew, Kok Pin Ng, Shahul Hameed, Simon Ks Ting, Adeline Sl Ng
{"title":"Evaluating the real-world performance of plasma pTau217 and pTau181 in a Southeast Asian tertiary memory clinic.","authors":"Yi Jayne Tan, Raziyeh Mohammadi, Seyed Ehsan Saffari, Nicole Isabella Tan, Louis Ss Lim, Shermine Hl Low, Louis Cs Tan, Hui Jin Chiew, Kok Pin Ng, Shahul Hameed, Simon Ks Ting, Adeline Sl Ng","doi":"10.1186/s13195-026-02008-5","DOIUrl":"https://doi.org/10.1186/s13195-026-02008-5","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147363747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-04DOI: 10.1186/s13195-026-01995-9
Elijah Mak, Scott A Przybelski, Robert I Reid, Heather J Wiste, Angela J Fought, Christopher G Schwarz, Matthew L Senjem, Prashanthi Vemuri, Clifford R Jack, Val J Lowe, Ronald C Petersen, Bradley F Boeve, Kejal Kantarci
{"title":"α-synuclein positivity is associated with decline in brain microstructure in the Alzheimer's disease spectrum.","authors":"Elijah Mak, Scott A Przybelski, Robert I Reid, Heather J Wiste, Angela J Fought, Christopher G Schwarz, Matthew L Senjem, Prashanthi Vemuri, Clifford R Jack, Val J Lowe, Ronald C Petersen, Bradley F Boeve, Kejal Kantarci","doi":"10.1186/s13195-026-01995-9","DOIUrl":"https://doi.org/10.1186/s13195-026-01995-9","url":null,"abstract":"","PeriodicalId":7516,"journal":{"name":"Alzheimer's Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147353264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：