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Relevance and application of clinical practice guidelines in different settings. 临床实践指南在不同环境中的相关性和应用。
R Blaauw
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引用次数: 0
Deep medicine … Navigating the intersection of technology, cognition and ethics in the digital age of medicine. 深度医学...... 数字医学时代的技术、认知和伦理交叉导航。
P D Gopalan, M Pienaar, S I Brokensha

The digital expansion in medicine and healthcare has been immense and extremely valuable. The biggest concern in the face of this inevitable growth is how we manage to keep contact with our patients and preserve the human touch so essential in healing. Digital healthcare should not be about technology replacing clinicians. Instead, it should be about augmenting and supplementing healthcare providers to improve the ways in which we deliver personalised healthcare. It is vital that we focus on how we can revitalise the patient-clinician relationship in this digital age.

医学和医疗保健领域的数字化发展是巨大的,也是极其宝贵的。面对这种不可避免的增长,我们最关心的问题是如何与患者保持联系,并保持治疗过程中必不可少的人文关怀。数字医疗不应是技术取代临床医生。相反,它应该是对医疗服务提供者的增强和补充,以改进我们提供个性化医疗服务的方式。在这个数字化时代,我们必须关注如何重振患者与医生之间的关系。
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引用次数: 0
The missed art of care? 失传的护理艺术?
Pub Date : 2023-04-12 eCollection Date: 2023-01-01 DOI: 10.7196/SAJCC.2023.v39i1.563
Alison Lupton-Smith
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引用次数: 0
Is scolding analogous to positive end-expiratory pressure (PEEP)? 责骂是否类似于呼气末正压(PEEP)?
S Singhal, M Verma, G Bhatia
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引用次数: 0
Malawian critical care nurses' views on the implementation of an educational intervention to enhance sustained use of an evidence-based endotracheal tube cuff pressure management guideline: A survey study. 马拉维重症护理护士对实施教育干预以增强持续使用循证气管插管袖口压力管理指南的看法:一项调查研究。
F Mpasa, Dalena R M van Rooyen, P J Jordan, D Venter, W Ten Ham-Baloyi

Background: Evidence-based guidelines can assist critical care nurses in promoting best practices, including those related to endotracheal tube cuff pressure management. However, these guidelines require tailored strategies to enhance their implementation, uptake, and sustained use in practice.

Objectives: To evaluate Malawian critical care nurses' views on the implementation of an endotracheal tube cuff pressure management guideline to enhance sustained guideline use.

Methods: An explorative-descriptive survey design was employed, using a questionnaire with closed- and open-ended questions that was distributed after implementation of an educational intervention based on an endotracheal tube cuff pressure management guideline. The questionnaire had a Cronbach's alpha score of 0.85.

Results: A total of 47 nurses working in four public and two private hospital intensive care units in Malawi participated. Quantitative findings showed that the majority of the participants (92%) indicated that the strategies used for the group that received the full intervention including both active (monitoring visits) and passive (a half-day educational session using a PowerPoint presentation, and a printed guideline and algorithm) strategies (intervention 1 group) were useful, clear and applicable and enhanced implementation of the guideline. These results were statistically significant (mean (standard deviation) 1.86 (0.84); t=6.07; p<0.0005). Qualitative data revealed three major themes related to recommendations for uptake and sustained use of the guideline in nursing practice: the guideline needs to be translated, updated, and made available to ICU staff; implementation strategies (continuous supervision and follow-up); and facilitating factors for successful implementation (education and training on guideline content, resources, and commitment to best practices).

Conclusion: The study highlighted that although the implementation strategies used were positively received by participants, they need to be further tailored to their context to enhance guideline uptake and sustained use in practice. Further study is required to ensure that tailored implementation strategies facilitate guideline uptake and sustained use, specifically in resource-constrained contexts.

Contributions of the study: The study findings can be used by nurses and academics when developing educational interventions for critical care units to enhance implementation of guidelines in this context.

背景:循证指南可以帮助重症护理护士推广最佳实践,包括与气管内套管压力管理相关的实践。然而,这些指导方针需要量身定制的战略来加强其在实践中的实施、吸收和持续使用。目的:评价马拉维重症护理护士对实施气管插管袖口压力管理指南的看法,以提高指南的持续使用。方法:采用探索性描述性调查设计,采用封闭式和开放式问卷,在实施基于气管内管袖口压力管理指南的教育干预后分发。问卷的Cronbach's alpha得分为0.85。结果:马拉维共有47名在四所公立医院和两所私立医院重症监护室工作的护士参加了调查。定量研究结果显示,大多数参与者(92%)表示,接受全面干预的组(包括主动(监测访问)和被动(使用PowerPoint演示的半天教育会议,以及打印的指南和算法)策略(干预1组)使用的策略是有用的,明确的和适用的,并加强了指南的实施。这些结果具有统计学意义(平均(标准差)1.86 (0.84);t = 6.07;结论:该研究强调,尽管所使用的实施策略得到了参与者的积极接受,但需要进一步根据他们的情况进行定制,以提高指南的吸收和在实践中的持续使用。需要进一步研究,以确保量身定制的实施策略促进指南的吸收和持续使用,特别是在资源有限的情况下。研究贡献:研究结果可用于护士和学者在制定重症监护病房的教育干预措施时,以加强这方面指南的实施。
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引用次数: 0
Healthcare professionals' perception of knowledge and implementation of Patient Safety Incident reporting and learning guidelines in specialised care units, KwaZulu‑Natal. 夸祖鲁-纳塔尔省专业护理单位的医疗保健专业人员对知识的认识和对患者安全事件报告和学习指南的执行情况。
T M H Gqaleni, S W Mkhize

Background: Despite the implementation of intervention strategies, incidents in specialised care units remain high and are of serious concern, worldwide.

Objectives: To assess the healthcare professionals' perception of knowledge and implementation of patient safety incident (PSI) reporting and learning guidelines in specialised care units of three selected public hospitals in KwaZulu-Natal, South Africa.

Methods: The study used a descriptive, cross-sectional survey design. A purposive sample targeted 237 healthcare professionals. An online structured questionnaire collected the data. Descriptive and inferential statistics were used to analyse data.

Results: A total of 181 questionnaires were returned, yielding a response rate of 76%. Notably, 83% of respondents had high-perceived knowledge of the PSI reporting and learning guidelines, while 98% had low perceptions of their implementation. The current unit (p=0.002) and shift of the day (p=0.008) were factors associated with the perception of good knowledge of PSI reporting and learning guidelines, as indicated by a p-value ≤0.05. The respondents' age (p=0.05), current unit (p=0.015), and shift of the day (p=0.000) were significantly associated with the perception of poor implementation of the PSI reporting and learning guidelines.

Conclusion: The respondents demonstrated a good perception of knowledge of PSI reporting and learning guidelines; however, the perception of the implementation was poor. Therefore, a revised implementation strategy coupled with periodical in-service training for healthcare professionals is recommended, to foster and facilitate effective adherence to PSI reporting and learning guidelines.

Contributions of the study: This study highlights the healthcare professionals' perception of knowledge and implementation of the Patient Safety Incident reporting and learning guidelines in specialised care units in South Africa. The results identified weaknesses in the implementation of the guidelines; hence the necessity for the development of effective strategies to improve patient safety.

背景:尽管实施了干预策略,在世界范围内,专门护理单位的事件仍然很高,引起了严重关注。目的:评估南非夸祖鲁-纳塔尔省选定的三家公立医院专科护理单位的医疗保健专业人员对患者安全事件(PSI)报告和学习指南的知识和实施情况的看法。方法:本研究采用描述性横断面调查设计。有目的的样本针对237名医疗保健专业人员。一份在线结构化问卷收集了数据。采用描述性统计和推理统计对数据进行分析。结果:共回收问卷181份,回复率76%。值得注意的是,83%的受访者对PSI报告和学习指南的认知程度较高,而98%的受访者对其实施的认知程度较低。当前单位(p=0.002)和一天的班次(p=0.008)是感知PSI报告和学习指南良好知识的相关因素,p值≤0.05。受访者的年龄(p=0.05),当前单位(p=0.015)和一天的班次(p=0.000)与PSI报告和学习指南执行不良的看法显着相关。结论:被调查者对PSI报告和学习指南的知识有良好的感知;然而,人们对执行情况的看法很差。因此,建议修订实施战略,并定期对医疗保健专业人员进行在职培训,以促进和促进有效遵守PSI报告和学习指南。本研究的贡献:本研究强调了南非专业护理单位的医疗保健专业人员对患者安全事件报告和学习指南的知识和实施的看法。结果查明了准则执行方面的弱点;因此,有必要制定有效的战略来提高患者的安全。
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引用次数: 1
Clinical features and outcomes of patients with myasthenia gravis admitted to an intensive care unit: A 20-year retrospective study. 重症监护病房重症肌无力患者的临床特征和预后:一项20年回顾性研究
R Morar, F Seedat, G A Richards

Background: There are limited data on the clinical characteristics and outcomes of patients with myasthenia gravis (MG) admitted to the intensive care unit (ICU) at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH).

Objectives: The aim was to study the clinical characteristics and outcomes of patients with MG admitted to the CMJAH over two decades.

Methods: A retrospective study was undertaken of patients with MG admitted to the multidisciplinary ICU of CMJAH over a 20-year period, from 1998 to 2017. Demographic data, clinical features, management and outcomes of patients were assessed and reviewed from the case records.

Results: Thirty-four patients with MG were admitted to the ICU during this period: 24 female and 10 male. The mean age ± SD was 37.4 ± 13.0 years, with a range of 16 - 66 years. Four patients were human immunodeficiency virus (HIV)-positive. The mean length of stay (LOS) in ICU was 10.6 ± 20.1 days, ranging from 1 to 115 days. Two patients were diagnosed with MG in the ICU after failure to wean from the ventilator. Overall, 22 patients were intubated and ventilated on admission. Morbidities included self-extubation, aspiration pneumonia and iatrogenic pneumothorax. History of thymectomy was present in 12 patients. The treatments received for MG included pyridostigmine (73.5%), corticosteroids (55.9%), azathioprine (35.3%), plasmapheresis (26.5%) and intravenous immunoglobulin (8.8%). The overall mortality in the ICU was 5.9%.

Conclusion: MG is a serious disorder with considerable morbidity and mortality. It is, however, a potentially manageable disease, provided that appropriate ICU resources are available.

Contributions of the study: This study provides further insight into the characteristics and outcomes of myasthenia gravis patients in ICU, within a South African context.

背景:在Charlotte Maxeke约翰内斯堡学术医院(CMJAH)重症监护室(ICU)收治的重症肌无力(MG)患者的临床特征和预后数据有限。目的:目的是研究二十年来CMJAH收治的MG患者的临床特征和预后。方法:回顾性研究1998年至2017年20年间CMJAH多学科ICU收治的MG患者。从病例记录中评估和回顾患者的人口统计数据、临床特征、管理和结局。结果:34例MG患者在此期间入住ICU,其中女性24例,男性10例。平均年龄±SD为37.4±13.0岁,年龄范围16 ~ 66岁。4例患者为人类免疫缺陷病毒(HIV)阳性。平均住院时间(LOS)为10.6±20.1天,1 ~ 115天。两名患者在脱离呼吸机失败后在ICU被诊断为MG。总体而言,22例患者在入院时进行了插管和通气。发病包括自我拔管、吸入性肺炎和医源性气胸。12例患者有胸腺切除术史。MG的治疗包括吡哆斯的明(73.5%)、皮质类固醇(55.9%)、硫唑嘌呤(35.3%)、血浆置换(26.5%)和静脉注射免疫球蛋白(8.8%)。ICU的总死亡率为5.9%。结论:MG是一种严重的疾病,发病率和死亡率都很高。然而,如果有适当的ICU资源,这是一种潜在的可控疾病。研究贡献:本研究为南非ICU重症肌无力患者的特征和预后提供了进一步的见解。
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引用次数: 0
Cochrane Corner: The use of anticoagulants in patients hospitalised with COVID-19. Cochrane Corner: COVID-19住院患者抗凝血剂的使用。
N Gloeck, A Jaca, T Kredo, G Calligaro

Background: In this Cochrane Corner, we highlight the main findings of a Cochrane Review by Flumignan et al. entitled 'Anticoagulants for people hospitalised with COVID-19' and discuss the implications of these findings for research and practice in South Africa. In particular, we underscore the need for additional, high-quality, randomised controlled trials comparing different intensities of anticoagulation in patients with COVID-19 illness. Individuals in the intensive care unit and those hospitalised with another illness who are incidentally found to be infected with SARS-CoV-2 should still only be treated with prophylactic-dose low-molecular-weight heparin.

Contributions of the study: This Cochrane Corner summarises findings in a recent systematic review on the use of anticoagulation in people hospitalised with COVID-19, and provides insights on the implications of these findings for implementation by clinicians in South Africa. It highlights the need for clinicians to balance the benefits and harms of providing an anticoagulant, while considering the patients underlying risk for bleeding and thromboembolism.

背景:在这个Cochrane专区,我们重点介绍了Flumignan等人发表的一篇题为“COVID-19住院患者的抗凝剂”的Cochrane综述的主要发现,并讨论了这些发现对南非研究和实践的影响。我们特别强调,需要进行额外的、高质量的、随机对照试验,比较COVID-19患者不同强度的抗凝治疗。重症监护病房的患者和因其他疾病住院的患者,如果偶然发现感染了SARS-CoV-2,仍应仅使用预防剂量的低分子肝素进行治疗。本研究的贡献:Cochrane Corner总结了最近一项关于COVID-19住院患者抗凝治疗使用的系统综述的发现,并就这些发现对南非临床医生实施的影响提供了见解。它强调临床医生需要平衡提供抗凝剂的利弊,同时考虑患者出血和血栓栓塞的潜在风险。
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引用次数: 0
Moral distress among critical care nurses when excecuting do-not-resuscitate (DNR) orders in a public critical care unit in Gauteng. 在豪登省的一个公共重症监护室执行不复苏(DNR)命令时,重症护理护士的道德困境。
S Ntseke, I Coetzee, T Heyns

Background: A critical care unit admits on a daily basis patients who are critically ill or injured. The condition of these patients' may deteriorate to a point where the medical practitioner may prescribe or decide on a 'do not resuscitate' (DNR) order which must be executed by a professional nurse, leading to moral distress which may manifest as poor teamwork, depression or absenteeism.

Objectives: To explore and describe factors contributing to moral distress of critical care nurses executing DNR orders.

Design: The explorative descriptive qualitative design was selected to answer the research questions posed.

Methods: Critical care nurses of a selected public hospital in Gauteng Province were selected via purposive sampling to participate in the study, and data were collected through semi-structured interviews.

Particpants: A shift leader assisted with selection of participants who met the eligibility criteria. The mean age of the participants was 36 years; most of them had more than five years' critical care nursing experience. Twelve critical care nurses were interviewed when data saturation was reached. Thereafter two more interviews were conducted to confirm data saturation. A total of 14 interviews were conducted.

Results: Tesch's eight-step method was utilised for data analysis. The findings were classified under three main themes: moral distress, communication of DNR orders and unavailability of psychological support for nurses.

Conclusion: The findings revealed that execution of DNR orders is a contributory factor for moral distress in critical care nurses. National guidelines and/or legal frameworks are required to regulate processes pertaining to the execution of DNR orders. The study further demonstrated the need for unit-based ethical platforms and debriefing sessions for critical care nurses.

Contribution of the study: The main contribution of this study was to explore and describe the factors contributing to Moral distress when executing a DNR order. This study raised awareness amongst healthcare providers on the factors contributing to moral distress amongst critical care nurses. This study highlighted the importance of developing national guidelines and legal frameworks pertaining to execution of DNR orders. This study alluded to the value of initiating debriefing sessions for critical care nurses involved in the execution of DNR orders.

背景:重症监护病房每天收治危重病人或重伤病人。这些病人的病情可能会恶化到某种程度,医生可能会开出或决定“不复苏”(DNR)命令,而这必须由专业护士执行,从而导致道德上的痛苦,表现为团队合作不力、抑郁或缺勤。目的:探讨重症护理护士执行DNR令时道德困扰的影响因素。设计:选择探索性描述性定性设计来回答研究提出的问题。方法:选择豪登省某公立医院的重症监护护士,采用有目的抽样的方法参与研究,采用半结构化访谈的方式收集资料。参与者:一位领班协助选择符合资格标准的参与者。参与者的平均年龄为36岁;他们大多有5年以上的重症监护护理经验。当数据达到饱和时,对12名重症护理护士进行了访谈。此后又进行了两次访谈以确认数据饱和度。共进行了14次访谈。结果:采用Tesch八步法进行数据分析。调查结果分为三个主要主题:道德困扰、急救命令的沟通和护士无法获得心理支持。结论:急救令的执行是重症护理护士道德困扰的一个因素。需要国家指南和/或法律框架来规范与DNR命令执行有关的流程。该研究进一步证明了重症护理护士需要基于单位的道德平台和述职会议。研究贡献:本研究的主要贡献是探索和描述在执行DNR命令时导致道德困扰的因素。本研究提高了医疗服务提供者对重症护理护士道德困扰因素的认识。这项研究强调了制定与执行DNR命令有关的国家指导方针和法律框架的重要性。本研究暗示了启动述职会议的价值危重护理护士参与执行DNR命令。
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引用次数: 0
Carbon dioxide levels of ventilated adult critically ill post-operative patients on arrival at the intensive care unit. 成人危重手术后通气患者到达重症监护病房时的二氧化碳水平。
M Slave, J Scribante, H Perrie, F Lambat

Background: The transportation of critically ill patients presents a precarious situation in which adverse events may occur. At Chris Hani Baragwanath Academic Hospital (CHBAH) patients were manually ventilated using a manual resuscitator bag during transportation from theatre to the intensive care unit (ICU).

Objectives: To evaluate the arterial partial pressure of carbon dioxide (PaCO2 ) levels of ventilated adult critically ill post-operative patients on arrival at the ICU at CHBAH.

Methods: This was a cross-sectional study using convenience sampling. Pre- and post-transportation arterial blood gases were obtained from 47 patients.

Results: There was a statistically significant difference in the pre- and post-transport PaCO2 level (p=0.03), with a mean difference of 3.3 mmHg. The pre- and post-transport arterial partial pressure of oxygen (PaO2 ) level (p≤0.001) and the week and weekend pre-transport (p≤0.001) and post-transport (p=0.01) PaCO2 were statistically significantly different. No statistically significant difference was found in the other arterial blood gas parameters or in the post-transport PaCO2 of those patients (26 (55.3%)), who received a neuromuscular blocking drug compared with those that did not. Adverse events were noted during 12 (25.6%) of the transports, 5 (41.7%) of which were patient-related, and 7 (58.3%) of which were infrastructure-related.

Conclusion: There was a statistically but not clinically significant difference in the pre- and post-transport PaCO2 level and between week and weekend transportations. Hypercarbia was the most common derangement in all transports. Adverse events occurred during one-quarter of transportations.

Contributions of the study: This study evaluated the PaCO2 levels of critically ill patients at CHBAH during transportation from theatre to the ICU. The findings indicate that manual ventilation was not injurious. The authors recommend reproducing the study in patients with severe ARDS and pulmonary hypertension to ascertain if manual ventilation is safe in this population; and also with healthcare practitioners other than anaesthesiologists, who may not be as experienced in manual ventilation.

背景:危重病人的运输呈现出可能发生不良事件的不稳定情况。在Chris Hani Baragwanath学术医院(CHBAH),患者在从手术室到重症监护病房(ICU)的运输过程中使用手动复苏袋进行人工通气。目的:评价CHBAH通气成人危重症术后患者到达ICU时动脉二氧化碳分压(PaCO2)水平。方法:采用方便抽样的横断面研究。采集了47例患者运输前后的动脉血气。结果:转运前后PaCO2水平差异有统计学意义(p=0.03),平均差异为3.3 mmHg。运前、运后动脉血氧分压(PaO2)水平(p≤0.001)、运前、运后一周、周末PaCO2水平(p≤0.001)差异均有统计学意义。与未接受神经肌肉阻断药物治疗的患者相比,接受神经肌肉阻断药物治疗的患者(26例(55.3%))的其他动脉血气参数或转运后PaCO2无统计学差异。12例(25.6%)转运发生不良事件,其中5例(41.7%)与患者相关,7例(58.3%)与基础设施相关。结论:转运前后PaCO2水平、周周转运与周末转运之间差异有统计学意义,但无临床意义。高碳血症是所有运输中最常见的紊乱。不良事件发生在四分之一的运输过程中。研究贡献:本研究评估了CHBAH危重患者从手术室转移到ICU期间的PaCO2水平。结果表明,人工通气是无害的。作者建议在严重急性呼吸窘迫综合征和肺动脉高压患者中重复这项研究,以确定人工通气在这一人群中是否安全;还有麻醉医生以外的医疗从业人员,他们在手动通气方面可能没有经验。
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引用次数: 0
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The Southern African journal of critical care : the official journal of the Critical Care Society
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