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Serious Medical and Psychosocial Complications in Pregnant and Postpartum Adolescents at a Pediatric Emergency Department. 儿科急诊室中怀孕和产后青少年的严重医疗和心理并发症。
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24072
Leman Akcan Yıldız, Halise Akça, Funda Kurt, Ayla Akça Çağlar

This study aimed to describe the clinical characteristics and serious medical and psychosocial complications of pregnant and postpartum adolescent patients at a pediatric emergency department (PED). Demographic and clinical data of all pregnant and postpartum adolescents who presented to the PED of a single tertiary referral hospital between January 2020 and January 2023 were collected and documented retrospectively. Twenty-seven patients with a mean age of 16.7 ± 0.8 years were included in the study. The main presenting complaints were abdominal pain (n = 9), suspicion of pregnancy (n = 5), cough, seizure, and vomiting (3 patients each). Potentially life-threatening medical complications included stroke (n = 3), placental abruption (n = 1), and carbon monoxide intoxication (n = 1). Sexual assault (n = 4), physical assault (n = 2), recurrent pregnancies (n = 5), and suicide attempts (n = 4) were serious psychological and social complications in our patient group. Pregnant and post-partum adolescents may present to PED with serious lifethreatening complications, and permanent sequelae may occur. In addition to sexual and physical violence, various psychological problems are comorbid conditions. These patients should be managed with a multidisciplinary biopsychosocial approach, and these issues considered in their acute treatment and follow-up at emergency departments.

本研究旨在描述一家儿科急诊科(PED)的怀孕和产后青少年患者的临床特征以及严重的医疗和心理并发症。研究收集并回顾性记录了2020年1月至2023年1月期间在一家三级转诊医院儿科急诊科就诊的所有怀孕和产后青少年的人口统计学和临床数据。研究共纳入 27 名患者,平均年龄(16.7±0.8)岁。主要主诉为腹痛(9 例)、怀疑怀孕(5 例)、咳嗽、抽搐和呕吐(各 3 例)。可能危及生命的医疗并发症包括中风(3 例)、胎盘早剥(1 例)和一氧化碳中毒(1 例)。性侵犯(4 例)、人身攻击(2 例)、反复妊娠(5 例)和自杀未遂(4 例)是本组患者严重的心理和社会并发症。怀孕和产后的青少年到 PED 就诊时可能会出现严重的危及生命的并发症,并可能出现永久性后遗症。除了性暴力和身体暴力,各种心理问题也是并发症。这些患者应采用多学科生物-心理-社会方法进行管理,并在急诊科的急性治疗和随访中考虑这些问题。
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引用次数: 0
Extracorporeal Membrane Oxygenation after Pediatric Cardiac Surgery: A Single-Center Experience. 小儿心脏手术后的体外膜氧合:单中心经验
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.23291
Edin Botan, Ayşe Durak Aslan, Emrah Gün, Merve Havan, Nur Dikmen, Anar Gurbanov, Burak Balaban, Fevzi Kahveci, Hasan Özen, Hacer Uçmak, Özlem Selvi Can, Selen Karagözlü, Mehmet Cahit Sarıcaoğlu, Zeynep Eyileten, Tayfun Uçar, Ercan Tutar, Ahmet Rüçhan Akar, Mustafa Adnan Uysalel, Tanıl Kendirli

Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment option providing cardiopulmonary support when standard therapies prove insufficient for reversible diseases. The mean objective of this study was to evaluate our center's experience with ECMO following pediatric cardiac surgery. This retrospective study was conducted in our pediatric intensive care unit (PICU) between November 2014 and March 2021 and included patients who received ECMO following cardiac surgery. Over the 7-year period, 324 patients underwent cardiac surgery, of which 24 (7.4%) required ECMO support. Among them, 13 (54.2%) were female, with a median age of 16.0 (2.0- 208) months and a median weight of 7.0 (3.5-70) kg. The mean vasoactive inotrope score (VIS) was 53.9 ± 44.5. Atrioventricular septal defect repair was the most common surgical procedure (n = 8/24, 41.6%). The primary indication for ECMO was low cardiac output syndrome (LCOS) in 14 (58.3%) patients. The median duration of ECMO support was 6.0 (1.0-46.0) days. Nonsurvivors had significantly higher Pediatric Risk Score of Mortality (PRISM) III scores (P = .014) and VIS scores during the pre-ECMO period (P = .004). Early or late neurological complications developed in 12 (50%) patients, with significant differences in lactate levels and pH levels preECMO between those with and without neurological complications (P = .01, P = .02, respectively). We successfully decannulated 16 (66.6%) patients, with a final survival rate of 12 (50%). ECMO plays a crucial role in providing pre- and post-cardiac surgery support for children. LCOS remains the main indication, and high PRISM III and VIS scores are valuable predictors of outcomes.

体外膜肺氧合(ECMO)是一种挽救生命的治疗方法,可在标准疗法不足以治疗可逆性疾病时提供心肺支持。本研究的主要目的是评估本中心在小儿心脏手术后使用 ECMO 的经验。这项回顾性研究于 2014 年 11 月至 2021 年 3 月期间在我们的儿科重症监护病房(PICU)进行,包括心脏手术后接受 ECMO 的患者。在这 7 年间,共有 324 名患者接受了心脏手术,其中 24 人(7.4%)需要 ECMO 支持。其中 13 人(54.2%)为女性,中位年龄为 16.0(2.0- 208)个月,中位体重为 7.0(3.5-70)公斤。血管活性肌力素评分(VIS)的平均值为(53.9 ± 44.5)分。房室间隔缺损修补术是最常见的手术方法(n = 8/24,41.6%)。14 名患者(58.3%)的 ECMO 主要适应症是低心排量综合征(LCOS)。ECMO 支持的中位持续时间为 6.0 (1.0-46.0) 天。非存活患者的儿科死亡率风险评分(PRISM)III 评分(P = .014)和 ECMO 前的 VIS 评分(P = .004)明显更高。12名患者(50%)出现了早期或晚期神经系统并发症,出现和未出现神经系统并发症的患者在ECMO前的乳酸水平和pH水平存在显著差异(分别为P = .01和P = .02)。我们成功为 16 例(66.6%)患者解除了封管,最终存活率为 12 例(50%)。ECMO 在为儿童提供心脏手术前后支持方面发挥着至关重要的作用。LCOS 仍是主要适应症,PRISM III 和 VIS 高分是预测预后的重要指标。
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引用次数: 0
Associated Congenital Abnormalities and Physical Phenotype in Patients with Diamond-Blackfan Anemia May Be Overlooked. 菱形-黑范氏贫血症患者的相关先天畸形和身体表型可能会被忽视。
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-06-17 DOI: 10.5152/TurkArchPediatr.2024.23193
Gulare Soltanova, Niham Avcu Oral, Fatma Gümrük, Pelin Özlem Şimşek Kiper, Şule Ünal

Diamond-Blackfan anemia (DBA) is a rare and inherited form of erythroid aplasia, characterized by severe macrocytic anemia, congenital malformations, and predisposition to cancer. The purpose of this study is to determine the congenital abnormalities and dysmorphological features of DBA patients in a cross-sectional manner. The study group included patients who had diagnosis of DBA between 1983 and 2017. Dysmorphological examinations of the patients were performed by an experienced dysmorphologist and also echocardiography and abdominal ultrasonography were performed in order to figure out cardiac and urogenital abnormalities. A total of 45 patients were examined in this study. Dysmorphological examination, echocardiography, and abdominal ultrasonography revealed the rate of congenital abnormalities as high as 88.7%. In consideration of the congenital abnormalities, the most common findings were craniofacial, followed by skeletal abnormalities. The rate of anomalies was found higher in our series of patients than that have been previously reported, most probably due to the evaluations being performed by a dysmorphologist in our cohort and not only depending on patient records or hematologists' physical examination.

菱形-贝克范贫血症(DBA)是一种罕见的遗传性红细胞再生障碍,以严重的巨幼红细胞性贫血、先天畸形和易患癌症为特征。本研究的目的是以横断面方式确定 DBA 患者的先天性异常和畸形特征。研究对象包括1983年至2017年间确诊为DBA的患者。由经验丰富的畸形学家对患者进行畸形检查,同时进行超声心动图和腹部超声波检查,以确定心脏和泌尿生殖系统的异常。本研究共对 45 名患者进行了检查。畸形检查、超声心动图和腹部超声波检查显示,先天性畸形率高达 88.7%。在先天性畸形中,最常见的是颅面畸形,其次是骨骼畸形。在我们的系列患者中,畸形率高于之前的报道,这很可能是因为在我们的队列中,由畸形学家进行评估,而不仅仅依赖于患者记录或血液学专家的体格检查。
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引用次数: 0
Trends in Causative Organisms and Antimicrobial Resistance in Late-onset Neonatal Sepsis. 晚期新生儿败血症的致病菌和抗菌药耐药性趋势。
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-06-17 DOI: 10.5152/TurkArchPediatr.2024.24006
Ayberk Özkavaklı, Ebru Yalın İmamoğlu, Neslihan Önder, Serhat İmamoğlu, Hüsnü Fahri Ovalı

The aim of this study was to evaluate the antibiotic resistance of microorganisms isolated in cases of culture-positive nosocomial late-onset neonatal sepsis in the neonatal intensive care unit. Infants admitted to our neonatal intensive care unit between October 2015 and June 2022 were retrospectively screened. A total of 458 different cultures from 386 sepsis incidents in 250 infants were analyzed. Over an 8-year period, 407 cases of culture-positive nosocomial late-onset neonatal sepsis were reviewed in a total of 4244 infants. Twenty-one cases were excluded due to insufficient data. The incidence of culture-positive nosocomial sepsis was 6.3%. Coagulase-negative Staphylococcus and Staphylococcus aureus were the most common gram-positive bacteria found in cultures. Resistance to ampicillin and cephalosporin treatments was high, while resistance to vancomycin, teicoplanin, and linezolid was low. Klebsiella spp. were the most frequent gram-negative bacteria isolated in cultures and showed high resistance to non-carbapenembased regimens. The only fungal microorganisms isolated in cultures were Candida spp., which had a high mortality rate despite their low resistance profile. The mortality rate due to nosocomial sepsis was 19.6%. Our study demonstrated that microorganisms and their antibiotic resistance profiles changed over time in the newborn intensive care unit. Gram-negative pathogens exhibited high antibiotic resistance, while fungi had high mortality rates. It is essential to adjust empirical antibiotic regimens for nosocomial sepsis based on thorough surveillance.

本研究旨在评估新生儿重症监护室培养阳性的晚期新生儿败血症病例中分离到的微生物的抗生素耐药性。我们对 2015 年 10 月至 2022 年 6 月期间新生儿重症监护室收治的婴儿进行了回顾性筛查。对 250 名婴儿的 386 起败血症事件中的 458 份不同培养物进行了分析。在 8 年的时间里,共回顾了 4244 名婴儿中培养阳性的 407 例晚期新生儿败血症病例。由于数据不足,21 例病例被排除在外。培养阳性的院内败血症发生率为 6.3%。凝固酶阴性葡萄球菌和金黄色葡萄球菌是培养物中最常见的革兰氏阳性细菌。对氨苄西林和头孢菌素的耐药性较高,而对万古霉素、替考拉宁和利奈唑胺的耐药性较低。克雷伯菌属是培养物中最常分离到的革兰氏阴性菌,对非碳青霉烯类疗法的耐药性很高。培养物中分离出的唯一真菌微生物是念珠菌属,尽管其耐药性较低,但死亡率却很高。院内败血症导致的死亡率为 19.6%。我们的研究表明,新生儿重症监护室中的微生物及其抗生素耐药性随时间推移而变化。革兰氏阴性病原体表现出较高的抗生素耐药性,而真菌的死亡率较高。在全面监测的基础上调整治疗院内败血症的经验性抗生素方案至关重要。
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引用次数: 0
RE: Comment On: Change in the Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes in the Central Anatolia Region of Türkiye Over the Years Before and After the Coronavirus Disease 2019 Pandemic. RE:评论:2019 年冠状病毒疾病大流行前后几年土耳其中部安纳托利亚地区新诊断为 1 型糖尿病的儿童中糖尿病酮症酸中毒发生率的变化。
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-05-06 DOI: 10.5152/TurkArchPediatr.2024.246202
Serkan Bilge Koca, Mehmet Zahit Takcı, Recep Deniz, Serhan Özcan, Mehmet Çeleğen, Adem Dursun

Cite this article as: Koca SB, Takcı MZ, Deniz R, Özcan S, Çeleğen M, Dursun A. RE: Comment on: Change in the frequency of diabetic ketoacidosis in children with newly diagnosed type 1 diabetes in the Central Anatolia region of Turkey over the years before and after the coronavirus disease 2019 pandemic: A single-center experience. Turk Arch Pediatr. Published online May 6, 2024, doi: 10.5152/TurkArchPediatr.2024.246202.

本文引用如前:Koca SB, Takcı MZ, Deniz R, Özcan S, Çeleğen M, Dursun A. RE: Comment on:2019年冠状病毒疾病大流行前后几年土耳其中部安纳托利亚地区新诊断的1型糖尿病患儿中糖尿病酮症酸中毒发生频率的变化:单中心经验。Turk Arch Pediatr.2024年5月6日在线发表,doi: 10.5152/TurkArchPediatr.2024.246202.
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引用次数: 0
Sclerotherapy of a Symptomatic Renal Cyst. 无症状肾囊肿的硬化疗法
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-05-02 DOI: 10.5152/TurkArchPediatr.2024.24033
Tuğçe Merve Orbay, Hamza Özer, Serdar Moralıoğlu

Simple renal cysts are not commonly found in children. They occur in a small percentage of cases, with an incidence of 0.2%-0.5%. These cysts are typically solitary and develop in the renal cortex. Pain, infection, hematuria, hypertension, or obstruction of the collecting system are indications for treatment. When intervention is necessary, there are several ways to reduce cyst volume. In this report, we discuss the pediatric case of a solitary giant renal cyst and its therapeutic approach. We present a symptomatic pediatric renal cyst patient treated with a sclerosing agent. A simple renal cyst is a rare condition in children, and its treatment includes conservative management, percutaneous sclerosing agent injection, and surgical approach. Choosing the appropriate treatment according to the patient's condition and clinical symptoms is essential. We think that sclerotherapy should be the first-line therapy before surgery in symptomatic simple renal cysts.

单纯性肾囊肿在儿童中并不常见。发生率为 0.2%-0.5%。这些囊肿通常为单发,发生在肾皮质。疼痛、感染、血尿、高血压或集合系统阻塞是治疗的指征。在必须进行干预时,有几种方法可以减少囊肿体积。在本报告中,我们将讨论小儿单发巨大肾囊肿病例及其治疗方法。我们介绍了一位使用硬化剂治疗的无症状小儿肾囊肿患者。单纯性肾囊肿在儿童中较为罕见,其治疗方法包括保守治疗、经皮硬化剂注射和手术治疗。根据患者的病情和临床症状选择合适的治疗方法至关重要。我们认为,对于无症状的单纯性肾囊肿,硬化剂注射应作为手术前的一线治疗方法。
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引用次数: 0
Thirdhand Smoke Exposure Ignored by Pediatricians: A Cross-sectional Study. 儿科医生忽视的三手烟暴露:一项横断面研究
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-05-02 DOI: 10.5152/TurkArchPediatr.2024.23277
Gizem Özcan, Emine Kaygı Tartıcı, Binnaz Çelik

Thirdhand smoke (THS) is defined as the harmful substances in cigarette smoke that are absorbed into objects, people, and surfaces after smoking. This study aimed to determine the level of awareness of pediatricians working in a tertiary healthcare institution about THS exposure. In this cross-sectional study, participants were asked to fill out an information form in which we questioned the participant's age, sex, occupation in the institution, the exposure of pediatric patients to cigarette smoke during daily healthcare, tobacco product use status, smoking status in their home and car, behavior in case of smoking in closed areas where smoking is prohibited, and whether they knew the term of THS. Also, the Turkish version of The Beliefs About Third-Hand Smoke was used. Eighty-one participants, with a mean age of 34.2 ± 7.6 years, were included in the study. Fifty-six (69.1%) participants said they had never used tobacco products. Participants who had never used tobacco products (P = .005), never allowed smoking in their homes (P = .017) and cars (P = .001), had heard the definition of THS before (P = .013), and thought they knew it (P = .005) had higher total scale scores. There was no significant difference between the THS awareness levels of pediatricians who questioned children's exposure to cigarette smoke in their daily practice and those who did not (P = .491). Determining the awareness levels of pediatricians about THS will be an important step in preventing THS exposure in children.

三手烟(THS)是指吸烟后被物体、人和表面吸收的香烟烟雾中的有害物质。本研究旨在确定在一家三级医疗机构工作的儿科医生对接触三手烟的认知水平。在这项横断面研究中,我们要求参与者填写一份信息表,在表中我们询问了参与者的年龄、性别、在医疗机构的职业、儿科患者在日常医疗过程中的烟雾暴露情况、烟草制品使用情况、在家中和车内的吸烟情况、在禁止吸烟的封闭区域吸烟时的行为以及是否知道THS一词。此外,还使用了土耳其语版的《关于三手烟的信念》。研究共纳入 81 名参与者,平均年龄为(34.2±7.6)岁。56名参与者(69.1%)表示他们从未使用过烟草制品。从未使用过烟草制品(P = .005)、从不允许在家中(P = .017)和车内(P = .001)吸烟、以前听说过 THS 的定义(P = .013)以及认为自己了解该定义(P = .005)的参与者的量表总分较高。在日常工作中对儿童接触香烟的情况提出质疑的儿科医生和没有提出质疑的儿科医生对 THS 的认识水平没有明显差异(P = .491)。确定儿科医生对 THS 的认识水平将是预防儿童接触 THS 的重要一步。
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引用次数: 0
Erratum. 勘误。
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-05-02 DOI: 10.5152/TurkArchPediatr.2024.25024
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引用次数: 0
Can Complete Blood Count Parameters and Serum Electrolyte Levels Have a Predictive Role in Differential Diagnosis of Tuberculosis from Community-acquired Pneumonia in Children? 全血细胞计数参数和血清电解质水平能否在儿童结核病与社区获得性肺炎的鉴别诊断中发挥预测作用?
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-05-02 DOI: 10.5152/TurkArchPediatr.2024.24015
Deniz Aygün, Pınar Önal, Ayşe Ayzıt Kılınç, Fatih Aygün, Rengin Şiraneci, Haluk Çokuğraş

The complete blood count (CBC) parameters and the ratios regarding these parameters have been demonstrated to be useful diagnostic biomarkers for many infectious diseases. Herein, we aimed to evaluate and compare the usefulness of the predictive role of the CBC in the differential diagnosis of pulmonary tuberculosis (TB) from community-acquired pneumonia (CAP) in children. We also compared serum electrolyte levels between the 2 diseases. In this retrospective study, we analyzed the efficacy of CBC parameters and neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), plateletto-lymphocyte ratio (PLR), neutrophil-to-monocyte-plus-lymphocyte ratio (NMLR), and serum electrolyte levels in the differential diagnosis of pulmonary TB from CAP in children. We also classified patients with TB into 2 groups according to the microbiologic confirmation. We investigated whether there is any difference regarding these parameters in patients with positive microbiologic results. A total of 163 patients diagnosed with TB and CAP were included in this study. The WBC, neutrophil and monocyte counts, NLR, MLR, NMLR, mean platelet volume (MPV), and C-reactive protein (CRP) values were higher in CAP. There was statistical significance among serum sodium and phosphorus (P) levels between the 2 groups. Microbiologic confirmation was determined in 37 (35.5%) patients with the diagnosis of TB. The NLR, MLR, NMLR, CRP, and P values were significantly higher in patients with microbiologic confirmation. The results of the present study suggest that complete blood count parameters, NLR, MLR, NMLR, and CRP can be useful and cost-effective markers in differentiating pulmonary TB from CAP in the early stages of diagnosis.

全血细胞计数(CBC)参数以及与这些参数相关的比率已被证明是许多传染病的有用诊断生物标志物。在此,我们旨在评估和比较全血细胞计数在儿童肺结核(TB)与社区获得性肺炎(CAP)鉴别诊断中的预测作用。我们还比较了两种疾病的血清电解质水平。在这项回顾性研究中,我们分析了血细胞计数参数和中性粒细胞与淋巴细胞比值(NLR)、单核细胞与淋巴细胞比值(MLR)、血小板与淋巴细胞比值(PLR)、中性粒细胞与单核细胞加淋巴细胞比值(NMLR)以及血清电解质水平在儿童肺结核与社区获得性肺炎鉴别诊断中的功效。我们还根据微生物学确诊结果将肺结核患者分为两组。我们研究了微生物学结果呈阳性的患者在这些参数方面是否存在差异。本研究共纳入了 163 名确诊为肺结核和 CAP 的患者。CAP 患者的白细胞、中性粒细胞和单核细胞计数、NLR、MLR、NMLR、平均血小板体积(MPV)和 C 反应蛋白(CRP)值均较高。两组患者的血清钠和磷 (P) 水平有统计学意义。有 37 例(35.5%)患者的结核病诊断得到了微生物学证实。微生物学确诊患者的 NLR、MLR、NMLR、CRP 和 P 值明显较高。本研究结果表明,在诊断的早期阶段,全血细胞计数参数、NLR、MLR、NMLR 和 CRP 是区分肺结核和 CAP 的有用且经济有效的指标。
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引用次数: 0
Utilization of Whole-Body Magnetic Resonance Imaging in Challenging Diagnoses in Pediatric Rheumatology. 在小儿风湿病学的疑难诊断中使用全身磁共振成像。
IF 1.3 Q3 PEDIATRICS Pub Date : 2024-05-02 DOI: 10.5152/TurkArchPediatr.2024.23319
Eray Tunce, Kadir Ulu, Sevinç Taşar, Betül Sözeri

The aim of this study was to investigate the use of whole-body magnetic resonance imaging (WBMRI) in cases where we suspected rheumatic disease in our pediatric rheumatology clinic. We conducted a retrospective analysis of demographic, clinical, laboratory, and imaging data pertaining to pediatric patients who presented at our clinic and underwent WBMRI over the last 5 years. Our investigation targeted children experiencing diffuse musculoskeletal pain, where precise localization was challenging and suspicion of rheumatological pathology persisted despite inconclusive results from conventional diagnostic modalities. A total of 87 patients (33 female) underwent WBMRI at our clinic, with a median age (minimum-maximum) of 11.3 (0.5-18) years. Whole-body magnetic resonance imaging was performed in 4 patients suspected with dermatomyositis (DM) where muscle biopsy was not feasible, revealing muscle involvement and myositis. Additionally, WBMRI was utilized in 4 patients diagnosed with chronic nonbacterial osteomyelitis (CNO) to assess recurrence, identifying new active lesions in 3 patients. Among the remaining 79 patients, 34 received a new diagnosis of CNO. Clinically, supported by additional findings in laboratory and WBMRI, 18 were diagnosed with juvenile idiopathic arthritis (JIA), 5 with protracted febrile myalgia syndrome (PFMS), 5 with acute osteomyelitis, and 1 with viral myositis. The results were normal for 17 patients. Most of the WBMRIs conducted at the clinic under study were primarily performed on patients suspected of having CNO. Additionally, WBMRI was found to be supportive and beneficial in cases of suspected DM, PFMS, and JIA during the diagnosis.

本研究旨在调查全身磁共振成像(WBMRI)在儿科风湿病诊所疑似风湿病病例中的应用情况。我们对过去 5 年中在本诊所就诊并接受 WBMRI 检查的儿科患者的人口统计学、临床、实验室和成像数据进行了回顾性分析。我们的调查对象是患有弥漫性肌肉骨骼疼痛的儿童,这些儿童的精确定位具有挑战性,尽管传统诊断方法没有得出结论,但仍怀疑他们患有风湿病。共有 87 名患者(33 名女性)在本诊所接受了全身磁共振成像检查,中位年龄(最小-最大)为 11.3(0.5-18)岁。在无法进行肌肉活检的情况下,对 4 名疑似皮肌炎(DM)患者进行了全身磁共振成像检查,结果显示肌肉受累和肌炎。此外,还对 4 名被诊断为慢性非细菌性骨髓炎(CNO)的患者进行了全身磁共振成像,以评估复发情况,并在 3 名患者中发现了新的活动性病灶。在其余 79 名患者中,有 34 人被诊断为新的 CNO。在实验室和 WBMRI 附加结果的支持下,临床诊断为幼年特发性关节炎 (JIA)的有 18 人,长期发热性肌痛综合征 (PFMS) 的有 5 人,急性骨髓炎的有 5 人,病毒性肌炎的有 1 人。17名患者的结果正常。研究中的诊所进行的大多数 WBMRI 主要针对疑似 CNO 患者。此外,WBMRI 对疑似 DM、PFMS 和 JIA 病例的诊断也有辅助作用和益处。
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引用次数: 0
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Turkish archives of pediatrics
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