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Evaluation of Hepatosteatosis-Induced Increase in Fibrosity by Two-Dimensional Shear Wave Elastography in Children with Obesity and Comparison with Healthy Peers. 通过二维剪切波弹性成像评估肥胖症儿童肝硬化引起的纤维性增加并与健康儿童进行比较
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.23237
Hanife Gülden Düzkalır, Elif Söbü, Ömer Aydıner

Objective: The increase in the prevalence of obesity, nonalcoholic fatty liver disease (NAFLD), and related comorbidities in children creates a social and financial burden. In our study, we aimed to evaluate liver findings together with anthropometric and laboratory data with twodimensional shear wave elastography (2D-SWE), one of the SWE types, which is a noninvasive method for assessing tissue stiffness in children with obesity, and to obtain quantitative data that can be used in early diagnosis and follow-up.

Materials and methods: In our single-center, observational cross-sectional study, liver gray scale findings, 2D-SWE findings, anthropometric measurements, and laboratory values of 48 children with obesity and 50 healthy children aged between 5 and 18 years, both between groups and in prepubertal and pubertal subgroups, are compared.

Results: A significant difference was found in the liver stiffness indicator kilopascal (kPA) values and between aspartate aminotransferase values in the prepubertal period and alanine aminotransferase values in the pubertal period (P < .001). No significant difference was found between insulin, HOMA-IR, waist circumference, waist/height ratio, and kPA.

Conclusion: Two-dimensional shear wave elastography can be easily applied in the pediatric population as a practical, noninvasive, reproducible, and highly compatible technique. In this regard, 2D-SWE may be useful in the early diagnosis and follow-up of hepatosteatosis and fibrosis in children with obesity and NAFLD-risky cases.

目的:儿童肥胖症、非酒精性脂肪肝(NAFLD)及相关并发症发病率的上升造成了社会和经济负担。在我们的研究中,我们旨在通过二维剪切波弹性成像(2D-SWE)评估肝脏检查结果以及人体测量和实验室数据,二维剪切波弹性成像是 SWE 的一种类型,是评估肥胖症儿童组织僵硬度的一种无创方法,并获得可用于早期诊断和随访的定量数据:在我们的单中心观察性横断面研究中,比较了 48 名肥胖症儿童和 50 名 5 至 18 岁健康儿童的肝脏灰度结果、二维-SWE 结果、人体测量和实验室值,包括组间、青春期前和青春期亚组:结果:发现肝脏硬度指标千帕斯卡(kPA)值以及青春期前的天冬氨酸氨基转移酶值和青春期后的丙氨酸氨基转移酶值之间存在明显差异(P < .001)。胰岛素、HOMA-IR、腰围、腰围/身高比和 kPA 之间无明显差异:二维剪切波弹性成像技术作为一种实用、无创、可重复和高度兼容的技术,可轻松应用于儿科人群。因此,二维剪切波弹性成像可用于肥胖症和非酒精性脂肪肝高危病例儿童肝脂肪变性和肝纤维化的早期诊断和随访。
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引用次数: 0
Paediatrics and Child Health Need a United, Credible and Strong Pan-European Voice. 儿科和儿童健康需要一个统一、可信和强有力的泛欧声音。
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.242102
Berthold Koletzko
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引用次数: 0
A 9-Year-Old Female with an Abdominal Mass. 一名 9 岁女性的腹部肿块。
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.24025
Justin E Anderson, Don Walker, Farnaz Norozian, Kristina Domanski
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引用次数: 0
The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina. 小儿癌症患者希克曼导管相关并发症的频率、严重程度和风险因素:来自波斯尼亚和黑塞哥维那的单中心经验。
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.23179
Zlatan Zvizdic, Emin Zaimovic, Emir Milisic, Asmir Jonuzi, Una Glamoclija, Semir Vranic

Objective: This study aimed to identify the frequency, severity, and risk factors associated with Hickman catheter-related complications in children with hemato-oncological malignancies at the largest pediatric tertiary care unit in Bosnia and Herzegovina.

Materials and methods: A cross-sectional study was conducted on a cohort of pediatric cancer patients who underwent Hickman central venous catheters (CVCs) between January 2019 and December 2022. Mechanical, infectious, and thrombotic Hickman catheter-related complications were evaluated and analyzed. We also investigated possible risk factors associated with these complications.

Results: Seventy-one Hickman CVCs were inserted in 68 children (44 boys and 24 girls) at a mean age of 6.9 ± 4.6. Forty (58.8%) children had hematological malignancies and 28 (41.2%) solid cancers. The median follow-up after Hickman CVC insertion was 190 days (95% CI [160-212]) for 12 644 catheter days. During follow-up, 10 (14.1%) mechanical, 7 (9.9%) infectious, and 1 (1.4%) thrombotic complications were recorded (0.8, 0.48, and 0.08 for mechanical, infectious, and thrombotic complications per 1000 catheter days, respectively). A slightly higher incidence of complications was recorded in children with hematological malignancies (1.59 per 1000 catheter days) compared with children with solid cancers (1.22 complications per 1000 catheter days).

Conclusion: Using Hickman CVCs for long-term venous access in infusional chemotherapy for pediatric cancer patients is safe but is associated with significant morbidity.

研究目的本研究旨在确定波斯尼亚和黑塞哥维那最大的儿科三级医疗单位中血液肿瘤恶性肿瘤患儿出现希克曼导管相关并发症的频率、严重程度和相关风险因素:对2019年1月至2022年12月期间接受希克曼中心静脉导管(CVC)治疗的一组儿科癌症患者进行了横断面研究。对机械性、感染性和血栓性希克曼导管相关并发症进行了评估和分析。我们还调查了与这些并发症相关的可能风险因素:68名平均年龄为6.9 ± 4.6岁的儿童(44名男孩和24名女孩)接受了71例希克曼导管插入手术。40名儿童(58.8%)患有血液系统恶性肿瘤,28名儿童(41.2%)患有实体瘤。插入希克曼CVC后的随访中位数为190天(95% CI [160-212]),导管使用天数为12 644天。在随访期间,共记录到 10 例(14.1%)机械性并发症、7 例(9.9%)感染性并发症和 1 例(1.4%)血栓性并发症(每 1000 个导管日的机械性、感染性和血栓性并发症发生率分别为 0.8、0.48 和 0.08)。血液恶性肿瘤患儿的并发症发生率(每1000导管日1.59例)略高于实体瘤患儿(每1000导管日1.22例):结论:在小儿癌症患者的输液化疗中使用 Hickman CVC 进行长期静脉通路是安全的,但会导致严重的发病率。
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引用次数: 0
Switching from Deferasirox Dispersible Tablets to Deferasirox Film-Coated Tablets: Is There an Effect on Ferritin Levels in Children and Adolescents with Transfusion-Dependent Anemia? 从地拉罗司分散片转为地拉罗司薄膜衣片:对输血依赖性贫血儿童和青少年的铁蛋白水平有影响吗?
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.23262
Esra Arslantaş, Ali Ayçiçek, Sibel Akpınar Tekgündüz, Duygu Özkorucu Yıldırgan, Ayşe Özkan Karagenç, Tuba Nur Tahtakesen Güçer, Ayşe Gonca Kaçar, Cengiz Bayram, Nihal Özdemir

Objective: To investigate the effect of switching from deferasirox dispersible tablet (DT) to deferasirox film-coated tablet (FCT) on serum ferritin (SF) levels in transfusion-dependent patients.

Materials and methods: Patients who received regular erythrocyte transfusion and whose treatment was switched from DT to FCT were included in the study. FCT start date was taken as the index date. Patients were followed over 2 equal and long periods, both before and after index date.

Results: Thirty-two patients were included, and the comparison periods ranged from 4 to 12 months. The SF values increased from a median of 1723 ng/mL (range 717-5369 ng/mL) to 1.853 ng/mL (range 924-5478 ng/mL) after switching from DT to FCT (P = .036). While there was a significant increase in median SF after switching in Turkish patients (1467 ng/mL to 1778 ng/ mL, P = .010) and patients ≥12 years (1598-1848 ng/mL, P = .009), there was an insignificant (P = .859) decrease in SF in immigrant children. Considering only the post-switch period, there was a non-significant increase in median SF in the entire cohort, while SF decreased significantly in immigrant children (P = .026). No serious side effects were observed in any patient that would cause discontinuation of treatment.

Conclusion: Overall, higher SF value was observed with FCT compared to DT in short term. There were different results between patient groups. Our results suggest that FCT is more effective than DT in patients with high basal ferritin and who are actually incompatible with treatment and should be preferred first in these patients.

目的研究从地拉羅司分散片(DT)转为地拉羅司薄膜衣片(FCT)对输血依赖患者血清铁蛋白(SF)水平的影响:研究对象包括定期接受红细胞输注且治疗方法从 DT 转为 FCT 的患者。以 FCT 开始日期为指标日期。在指标日期之前和之后,对患者进行了两次等长的随访:研究共纳入 32 名患者,比较期从 4 个月到 12 个月不等。从 DT 转为 FCT 后,SF 值从中位数 1723 纳克/毫升(范围 717-5369 纳克/毫升)增至 1.853 纳克/毫升(范围 924-5478 纳克/毫升)(P = .036)。土耳其患者(1467 纳克/毫升至 1778 纳克/毫升,P = .010)和年龄≥12 岁的患者(1598-1848 纳克/毫升,P = .009)的中位数 SF 在转换后有明显增加,而移民儿童的 SF 下降不明显(P = .859)。仅考虑转换后时期,整个队列的 SF 中位数增加不显著,而移民儿童的 SF 显著下降(P = .026)。没有观察到任何患者出现严重的副作用而导致中断治疗:结论:总体而言,在短期内,FCT 的 SF 值高于 DT。结论:总体而言,在短期内,FCT 的 SF 值高于 DT。我们的研究结果表明,对于基础铁蛋白较高且实际上不适合治疗的患者,FCT 比 DT 更有效,因此应优先考虑这些患者。
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引用次数: 0
Recurrent Food-Induced Anaphylaxis in a Child: A Rare Case Report. 一名儿童反复发生食物诱发的过敏性休克:罕见病例报告
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.23242
Hülya Anıl, Feride Candan, Koray Harmancı
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引用次数: 0
Change in the Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes in the Central Anatolia Region of Turkey over the Years Before and After the Coronavirus Disease 2019 Pandemic: A Single-Center Experience. 土耳其安纳托利亚中部地区新诊断为 1 型糖尿病的儿童在 2019 年冠状病毒疾病大流行前后几年中发生糖尿病酮症酸中毒的频率变化:单中心经验。
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.23255
Serkan Bilge Koca, Mehmet Zahit Takcı, Recep Deniz, Serhan Özcan, Mehmet Çeleğen, Adem Dursun

Objective: The number of admissions for severe diabetic ketoacidosis (DKA) in children with newly diagnosed type 1 diabetes (T1D) increased during the coronavirus disease 2019 pandemic. We aimed to investigate whether there has been a change in this situation in recent years.

Materials and methods: All children with T1D who were diagnosed in our tertiary hospital between 2019 and 2023 were included. Plasma insulin, C-peptide, hemoglobin A1c (HbA1c), and antibodies against thyroid peroxidase, thyroglobulin, insulin, islet cell, glutamic acid decarboxylase, tissue transglutaminase IgA, and endomysium IgA were measured.

Results: The frequency of moderate-severe acidosis at admission, which increased after pandemic period compared to the pre-pandemic period, returns to its previous levels over time but still shows a statistical difference compared to the pre-pandemic period (P = .012). Age, blood gas pH and HCO3 level, C-peptide, HbA1c, and length of stay of children at the time of admission were compared year by year (years 2019-2023). No statistical differences were observed (P = .509, P = .181, P = .069, P = .469, P = .346, P = .946), respectively. A significant difference was observed in venous glucose (P .001) and insulin (P = .001) according to years. Also, no significant difference was found about the degree of acidosis according to age (P = .334).

Conclusion: Although the frequency of DKA in children with newly-diagnosed T1D increased in the first years of the pandemic, it has been decreasing over t.

目的:在2019年冠状病毒疾病大流行期间,新诊断为1型糖尿病(T1D)的儿童因严重糖尿病酮症酸中毒(DKA)入院的人数有所增加。我们旨在调查近年来这种情况是否发生了变化:纳入2019年至2023年期间在我院三级医院确诊的所有T1D患儿。测定血浆胰岛素、C肽、血红蛋白A1c(HbA1c)以及甲状腺过氧化物酶抗体、甲状腺球蛋白抗体、胰岛素抗体、胰岛细胞抗体、谷氨酸脱羧酶抗体、组织转谷氨酰胺酶IgA抗体和内膜IgA抗体:结果:与大流行前相比,入院时出现中重度酸中毒的频率在大流行后有所增加,但随着时间的推移又恢复到以前的水平,但与大流行前相比仍有统计学差异(P = .012)。对儿童入院时的年龄、血气 pH 值和 HCO3 水平、C 肽、HbA1c 和住院时间进行了逐年比较(2019-2023 年)。分别未观察到统计学差异(P = .509、P = .181、P = .069、P = .469、P = .346、P = .946)。在静脉血糖(P .001)和胰岛素(P = .001)方面,观察到不同年份的人有明显差异。此外,酸中毒的程度与年龄也无明显差异(P = .334):结论:尽管在大流行的最初几年,新诊断为 T1D 的儿童中发生 DKA 的频率有所增加,但随着时间的推移,这一频率一直在下降。
{"title":"Change in the Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes in the Central Anatolia Region of Turkey over the Years Before and After the Coronavirus Disease 2019 Pandemic: A Single-Center Experience.","authors":"Serkan Bilge Koca, Mehmet Zahit Takcı, Recep Deniz, Serhan Özcan, Mehmet Çeleğen, Adem Dursun","doi":"10.5152/TurkArchPediatr.2024.23255","DOIUrl":"10.5152/TurkArchPediatr.2024.23255","url":null,"abstract":"<p><strong>Objective: </strong>The number of admissions for severe diabetic ketoacidosis (DKA) in children with newly diagnosed type 1 diabetes (T1D) increased during the coronavirus disease 2019 pandemic. We aimed to investigate whether there has been a change in this situation in recent years.</p><p><strong>Materials and methods: </strong>All children with T1D who were diagnosed in our tertiary hospital between 2019 and 2023 were included. Plasma insulin, C-peptide, hemoglobin A1c (HbA1c), and antibodies against thyroid peroxidase, thyroglobulin, insulin, islet cell, glutamic acid decarboxylase, tissue transglutaminase IgA, and endomysium IgA were measured.</p><p><strong>Results: </strong>The frequency of moderate-severe acidosis at admission, which increased after pandemic period compared to the pre-pandemic period, returns to its previous levels over time but still shows a statistical difference compared to the pre-pandemic period (P = .012). Age, blood gas pH and HCO3 level, C-peptide, HbA1c, and length of stay of children at the time of admission were compared year by year (years 2019-2023). No statistical differences were observed (P = .509, P = .181, P = .069, P = .469, P = .346, P = .946), respectively. A significant difference was observed in venous glucose (P .001) and insulin (P = .001) according to years. Also, no significant difference was found about the degree of acidosis according to age (P = .334).</p><p><strong>Conclusion: </strong>Although the frequency of DKA in children with newly-diagnosed T1D increased in the first years of the pandemic, it has been decreasing over t.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differentiating Multisystem Inflammatory Syndrome in Children from Kawasaki Disease During the Pandemic. 大流行期间儿童多系统炎症综合征与川崎病的鉴别。
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.23192
Seher Şener, Ezgi Deniz Batu, Ümmüşen Kaya Akca, Erdal Atalay, Müşerref Kasap Cüceoğlu, Zeynep Balık, Özge Başaran, Tevfik Karagöz, Yasemin Özsürekçi, Yelda Bilginer, Seza Özen

Objective: We aimed to delineate the distinctive characteristics that aid in distinguishing between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C) with KD-like manifestations during the pandemic.

Materials and methods: We evaluated KD patients and MIS-C patients with KD-like symptoms admitted during the pandemic (between January 2021 and December 2022).

Results: Thirty-three MIS-C patients and 15 KD patients were included. Kawasaki disease patients were younger than MIS-C patients (3.4 vs. 7.6 years). Rash (P = .044, 100% vs. 75.7%), oral mucosal changes (P = .044, 100% vs. 75.7%), and cervical lymphadenopathy (P = .001, 93.3% vs. 42.4%) were more common in KD. Multisystem inflammatory syndrome in children: patients had more hypotension (P = .002, 45.4% vs. 0), gastrointestinal (P .001, 72.7% vs. 13.3%), and respiratory symptoms (P = .044, 24.2% vs. 0). Multisystem inflammatory syndrome in children patients also had low lymphocyte and thrombocyte counts and elevated levels of d-dimer, ferritin, and cardiac parameters, unlike KD patients. Multisystem inflammatory syndrome in children patients exhibited a notable reduction in left ventricular systolic function in echocardiography. Another significant difference with regard to management was the anakinra treatment, which was prescribed for MIS-C patients.

Conclusion: Although MIS-C patients might display a clinical resemblance to KD, several features could help differentiate between MIS-C and classical KD. Specific clinical (hypotension, gastrointestinal, and respiratory symptoms) and laboratory (low lymphocyte and thrombocyte counts with higher C-reactive protein, ferritin, d-dimer, and cardiac parameters) features are characteristic of MIS-C. In addition, divergence in management strategies is evident between the 2 diseases, as biologic drugs were more prevalently employed in MIS-C patients than in classical KD patients.

目的:材料与方法: 我们对大流行期间(2021年1月至2022年12月)收治的川崎病(KD)患者和有KD样表现的儿童多系统炎症综合征(MIS-C)患者进行了评估:我们对大流行期间(2021 年 1 月至 2022 年 12 月)收治的 KD 患者和有 KD 类似症状的 MIS-C 患者进行了评估:结果:共纳入 33 名 MIS-C 患者和 15 名 KD 患者。川崎病患者比 MIS-C 患者年轻(3.4 岁对 7.6 岁)。川崎病患者更常见皮疹(P = .044,100% 对 75.7%)、口腔粘膜变化(P = .044,100% 对 75.7%)和颈淋巴结病(P = .001,93.3% 对 42.4%)。儿童多系统炎症综合征:患者有更多的低血压(P = .002,45.4% 对 0)、胃肠道症状(P .001,72.7% 对 13.3%)和呼吸道症状(P = .044,24.2% 对 0)。与 KD 患者不同的是,儿童多系统炎症综合征患者的淋巴细胞和血小板计数偏低,d-二聚体、铁蛋白和心脏参数水平升高。在超声心动图检查中,儿童多系统炎症综合征患者的左心室收缩功能明显下降。在治疗方面的另一个明显差异是,MIS-C 患者需接受阿那金拉治疗:结论:虽然 MIS-C 患者的临床表现可能与 KD 相似,但有几个特征有助于区分 MIS-C 和传统 KD。特定的临床(低血压、胃肠道和呼吸道症状)和实验室(低淋巴细胞和血小板计数,较高的 C 反应蛋白、铁蛋白、二聚体和心脏参数)特征是 MIS-C 的特征。此外,这两种疾病的治疗策略也存在明显差异,MIS-C 患者比传统 KD 患者更倾向于使用生物药物。
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引用次数: 0
Gorlin Syndrome: A Comprehensive Evaluation of Skin Findings. 戈林综合征:皮肤检查结果的综合评估。
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.5152/TurkArchPediatr.2024.23231
Tuğba Atcı, Elizaveta Melnicova, Can Baykal

Objective: Although Gorlin syndrome has rich skin findings, there is limited information about their subtypes, features specific to this genodermatosis, and relationships with each other.

Materials and methods: The demographic characteristics as well as cutaneous and extracutaneous findings of consecutive Gorlin syndrome patients diagnosed during 23 years were evaluated retrospectively. The relationship between palmoplantar pitting and basal cell carcinoma (BCC) in this localization and the relationship between odontogenic keratocysts (OKCs) and epidermoid cysts were investigated.

Results: A total of 30 patients were diagnosed with Gorlin syndrome of whom 36.7% were children. BCC was the most common finding (90%) followed by OKCs (83.3%), skeletal system anomalies (76.7%), and palmoplantar pitting (76.7%). While classical BCC (63.3%) lesions were the predominant clinical subtype among all patients, acrochordon-like or small-sized papular BCCs were seen in 45.4% of pediatric patients. Three patients, 2 of whom were children, had BCC lesions in the palmoplantar region in association with palmoplantar pitting. Epidermoid cysts presenting clinically as solitary (n = 12) or a few nodules (n = 4) without punctum, located more commonly in acral areas (n = 10) were seen in 16 (53.3%) patients of whom 7 were children. Epidermoid cysts were seen in 60% of patients with OKCs, and the relationship between epidermoid cysts and OKCs was not statistically significant (P = .15). Extracutaneous tumors such as medulloblastoma (n = 3), cardiac fibroma (n = 1), and ameloblastoma (n = 1) were also recorded.

Conclusion: The awareness of papular or acrochordon-like BCCs, palmoplantar BCCs, and acral epidermoid cysts without punctum may facilitate early diagnosis of Gorlin syndrome in children.

目的:尽管戈林综合征有丰富的皮肤发现,但有关其亚型、这种基因皮肤病的特殊特征以及相互关系的信息却很有限:回顾性评估了 23 年间连续确诊的戈林综合征患者的人口统计学特征以及皮肤和皮肤外检查结果。研究了掌跖凹陷与基底细胞癌(BCC)之间的关系,以及牙源性角化囊肿(OKC)与表皮样囊肿之间的关系:共有30名患者被诊断为戈林综合征,其中36.7%为儿童。BCC 是最常见的病变(90%),其次是 OKC(83.3%)、骨骼系统异常(76.7%)和掌跖点状瘤(76.7%)。在所有患者中,典型 BCC(63.3%)病变是最主要的临床亚型,而在 45.4% 的儿童患者中,出现了尖丘疹样或小面积丘疹性 BCC。有 3 名患者(其中 2 名是儿童)的掌跖部位出现 BCC 病变,并伴有掌跖点状损害。表皮样囊肿临床表现为单发(12 例)或几个结节(4 例),无穿刺点,多发于尖锐湿疣部位(10 例),有 16 例(53.3%)患者,其中 7 例为儿童。60%的 OKC 患者有表皮样囊肿,表皮样囊肿与 OKC 之间的关系无统计学意义(P = .15)。此外,还记录到髓母细胞瘤(3 例)、心脏纤维瘤(1 例)和釉母细胞瘤(1 例)等皮外肿瘤:结论:对丘疹型或尖角型BCC、掌跖BCC和无点状突起的尖角表皮样囊肿的认识有助于早期诊断儿童戈林综合征。
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引用次数: 0
A Rare Clinical Finding in Ataxia Telangiectasia: Granulomatous Skin Lesion 共济失调性特朗吉可病的罕见临床表现:肉芽肿性皮肤病变
Q3 Medicine Pub Date : 2024-02-20 DOI: 10.5152/turkarchpediatr.2024.23283
Sezin Naiboğlu, S. Ulaş, Işılay Turan, F. Cipe, Begüm Çalım Gürbüz, Ç. Aydoğmuş
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引用次数: 0
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Turkish archives of pediatrics
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