Pub Date : 2021-01-01Epub Date: 2021-12-08DOI: 10.1007/s00740-021-00425-w
{"title":"Infektionsprophylaxe bei CED.","authors":"","doi":"10.1007/s00740-021-00425-w","DOIUrl":"https://doi.org/10.1007/s00740-021-00425-w","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 6","pages":"223"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39720970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-09-09DOI: 10.1007/s00740-021-00407-y
{"title":"Breit wirksam im Kampf gegen Entzündungen.","authors":"","doi":"10.1007/s00740-021-00407-y","DOIUrl":"https://doi.org/10.1007/s00740-021-00407-y","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 4","pages":"139"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39413611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-03-30DOI: 10.1007/s00740-021-00391-3
{"title":"Panorama.","authors":"","doi":"10.1007/s00740-021-00391-3","DOIUrl":"https://doi.org/10.1007/s00740-021-00391-3","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 2","pages":"44-45"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00740-021-00391-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25558002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-11-08DOI: 10.1007/s00740-021-00412-1
{"title":"Als strategischer Partner Grenzen überbrücken.","authors":"","doi":"10.1007/s00740-021-00412-1","DOIUrl":"https://doi.org/10.1007/s00740-021-00412-1","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 5","pages":"192-195"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39732053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-03-30DOI: 10.1007/s00740-021-00392-2
{"title":"Vielschichtige Mechanismen.","authors":"","doi":"10.1007/s00740-021-00392-2","DOIUrl":"https://doi.org/10.1007/s00740-021-00392-2","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 2","pages":"56-57"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00740-021-00392-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25558004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-08-23DOI: 10.1007/s00740-021-00405-0
Michael Müller
Resources for the rapid and comprehensive availability of reliable diagnostic tests were an important prerequisite for the detection and management of the pandemic triggered by the coronavirus disease 2019 (COVID-19). The capacity for the diagnostic tests had to be rapidly planned and established in early 2020 and had to be constantly expanded. The German healthcare system with dedicated and experienced specialists for laboratory medicine, clinical microbiology, virology and infection epidemiology was well prepared to meet these challenges, both professionally and organizationally. The experiences with the challenges in the first year of the pandemic are presented in this article.
{"title":"[Coronavirus disease 2019-Lessons learned für die Mikrobiologie und Labormedizin].","authors":"Michael Müller","doi":"10.1007/s00740-021-00405-0","DOIUrl":"https://doi.org/10.1007/s00740-021-00405-0","url":null,"abstract":"<p><p>Resources for the rapid and comprehensive availability of reliable diagnostic tests were an important prerequisite for the detection and management of the pandemic triggered by the coronavirus disease 2019 (COVID-19). The capacity for the diagnostic tests had to be rapidly planned and established in early 2020 and had to be constantly expanded. The German healthcare system with dedicated and experienced specialists for laboratory medicine, clinical microbiology, virology and infection epidemiology was well prepared to meet these challenges, both professionally and organizationally. The experiences with the challenges in the first year of the pandemic are presented in this article.</p>","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 4","pages":"132-138"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00740-021-00405-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39364489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-10-21DOI: 10.1007/s00740-021-00414-z
Dennis A Eichenauer, Gunnar Lachmann, Paul La Rosée
Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammation syndrome. In adults, secondary HLH is mostly observed. HLH is often triggered by infections, malignancies or autoimmune disorders. However, HLH cases in association with immunotherapies have been described recently. HLH in critically ill patients is often difficult to differentiate from sepsis. Both conditions can also be present at the same time. Early diagnosis and timely initiation of an adequate immunosuppressive therapy are essential for the further course and the prognosis of HLH. Therefore, HLH should represent a differential diagnosis in critically ill patients with persistent fever and additional symptoms (e.g. enlarged spleen, neurologic symptoms) or laboratory parameters (e.g. hyperferritinemia, cytopenia, increased transaminases) compatible with HLH. The diagnosis of HLH is made using the HLH-2004 criteria. The probability of the presence of HLH can be calculated using the HScore. High-dose corticosteroids represent the cornerstone of HLH treatment. Etoposide, immunoglobulins, anakinra or other drugs are added depending on the trigger. The course of HLH is influenced by the time of treatment initiation, the underlying trigger and the response to treatment. Generally, the prognosis of critically ill HLH patients is poor.
{"title":"[Hemophagocytic lymphohistiocytosis in critically ill patients].","authors":"Dennis A Eichenauer, Gunnar Lachmann, Paul La Rosée","doi":"10.1007/s00740-021-00414-z","DOIUrl":"https://doi.org/10.1007/s00740-021-00414-z","url":null,"abstract":"<p><p>Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammation syndrome. In adults, secondary HLH is mostly observed. HLH is often triggered by infections, malignancies or autoimmune disorders. However, HLH cases in association with immunotherapies have been described recently. HLH in critically ill patients is often difficult to differentiate from sepsis. Both conditions can also be present at the same time. Early diagnosis and timely initiation of an adequate immunosuppressive therapy are essential for the further course and the prognosis of HLH. Therefore, HLH should represent a differential diagnosis in critically ill patients with persistent fever and additional symptoms (e.g. enlarged spleen, neurologic symptoms) or laboratory parameters (e.g. hyperferritinemia, cytopenia, increased transaminases) compatible with HLH. The diagnosis of HLH is made using the HLH-2004 criteria. The probability of the presence of HLH can be calculated using the HScore. High-dose corticosteroids represent the cornerstone of HLH treatment. Etoposide, immunoglobulins, anakinra or other drugs are added depending on the trigger. The course of HLH is influenced by the time of treatment initiation, the underlying trigger and the response to treatment. Generally, the prognosis of critically ill HLH patients is poor.</p>","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 6","pages":"246-251"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39557779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-03-30DOI: 10.1007/s00740-021-00395-z
{"title":"Der Darm als Angriffsort.","authors":"","doi":"10.1007/s00740-021-00395-z","DOIUrl":"https://doi.org/10.1007/s00740-021-00395-z","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"24 2","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00740-021-00395-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25558003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01Epub Date: 2020-04-03DOI: 10.1007/s00740-020-00337-1
Verena Kienast
{"title":"Verzerrte Informationen: Zwischen Panikmache und Sorglosigkeit.","authors":"Verena Kienast","doi":"10.1007/s00740-020-00337-1","DOIUrl":"https://doi.org/10.1007/s00740-020-00337-1","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"23 2","pages":"45"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00740-020-00337-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37833853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01Epub Date: 2020-10-30DOI: 10.1007/s00740-020-00362-0
{"title":"Der Testfall und seine Folgen.","authors":"","doi":"10.1007/s00740-020-00362-0","DOIUrl":"https://doi.org/10.1007/s00740-020-00362-0","url":null,"abstract":"","PeriodicalId":75323,"journal":{"name":"Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift","volume":"23 5","pages":"246-247"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00740-020-00362-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38580436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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