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[The future of the concept of depression]. [抑郁症概念的未来]。
Pub Date : 1996-03-01
P Pichot

The history of the concept of depression is briefly reviewed. First described under the name of melancholia as a delusional state, then, since Esquirol, as a primary mood disorder, it was subdivided by Kraepelin in diseases characterised by an hypothetical etiology and is considered, since 1980, as a syndrome with many sub-varieties. The nature of the three possible models is discussed. The first two, until now used, which considered depression either as a disease or as a syndrome, are categorical. The first has been provisorily abandoned, due to the insufficiency of scientific proofs about the etio-pathogeny; the second, despite its growing complexity, is obviously not satisfactory. The third model, dimensional, which attracts a growing attention in other field of psychiatric nosology, offers for the time being a possible alternative.

简要回顾抑郁症概念的历史。首先以忧郁症的名义描述为一种妄想状态,然后,自Esquirol以来,作为一种原发性情绪障碍,Kraepelin将其细分为以假设病因为特征的疾病,自1980年以来,被认为是一种具有许多亚型的综合征。讨论了这三种可能模型的性质。到目前为止使用的前两种方法将抑郁症视为一种疾病或一种综合症,是绝对的。由于缺乏关于病因的科学证据,第一种方法已被暂时放弃;第二种方法尽管越来越复杂,但显然不能令人满意。第三种模型,维度,在精神病学的其他领域引起了越来越多的关注,暂时提供了一种可能的选择。
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引用次数: 0
[Guignol or the comedian's paradox]. [吉尼奥尔或喜剧演员的悖论]。
Pub Date : 1996-01-01
J P Marnier, A Ait Ameur, C Petit-Marnier, N Ostaptzeff, A Gisselmann, P Trapet

Our study is based on a puppet theatre performed with a group of children aged from six to eight who were experiencing a neurotic context. Guignol's playing reveals anguishes and defensive mechanisms as well as, regarding the actors, the ability to experience the comedy with authenticity without forgetting it is imaginary. The puppet theatre has allowed us to progress in a therapeutic process while continuing diagnostic exploration.

我们的研究是基于一个木偶剧院,一群年龄在6到8岁之间的儿童正在经历神经症。吉尼奥尔的表演揭示了痛苦和防御机制,对于演员来说,在不忘记它是想象的情况下真实地体验喜剧的能力。木偶剧场让我们在继续诊断探索的同时,在治疗过程中取得进展。
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引用次数: 0
[Return to work following myocardial infarct. effect of certain socioeconomic factors]. 心肌梗死后复工。某些社会经济因素的影响]。
Pub Date : 1996-01-01
P Lauwers, N Brancart

The influence of several socioeconomic factors in return to work following myocardial infarction has been evaluated for 55 male patients. Age, employment status and educational level are among the most determinant factors. Whereas, the financial resources appear less significant as an incentive to resumption of work.

本文对55例男性心肌梗死后重返工作岗位的社会经济因素进行了评估。年龄、就业状况和教育水平是最具决定性的因素。然而,财政资源作为恢复工作的激励因素似乎不那么重要。
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引用次数: 0
[Systemic approach to families dealing with cancer diagnosis, its treatment and its prognosis]. [对家庭处理癌症诊断、治疗和预后的系统方法]。
Pub Date : 1996-01-01
A Bodart, N Delvaux, A Segers-Laurent

This paper reviews and comments the literature related to the problems families have to deal with when cancer occurs, in a psychological and relational perspective. It addresses, among other topics, communication problems and the specific aspects of the different evolutional phases of the disease, and the subsystems of the family. Considering the dramatic effects of cancer within the family and the interdependency of the patient and his family in their adjustment to the disease, we propose that psychological evaluation and support should be offered to the family system as a whole.

本文从心理和关系的角度对癌症发生时家庭需要处理的问题的相关文献进行了综述和评论。除其他主题外,它还涉及沟通问题和疾病不同演变阶段的具体方面以及家庭的子系统。考虑到癌症对家庭的巨大影响,以及患者及其家人在适应疾病过程中的相互依赖性,我们建议应向整个家庭系统提供心理评估和支持。
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引用次数: 0
The management of drug-resistant, persistent and unpleasant auditory hallucinations. 耐药、持续性、不愉快幻听的处理。
Pub Date : 1996-01-01
D Lecompte

This article attempts to give an overview of the main cognitive-behavioral therapeutic approaches in order to reduce persistent, unpleasant and drug-resistant auditory hallucinations. These procedures are based on operant conditioning principles and cognitive self-management techniques. A brief case history is reported to illustrate the therapeutic interventions.

本文试图概述主要的认知行为治疗方法,以减少持续的,不愉快的和耐药的幻听。这些程序是基于操作性条件反射原则和认知自我管理技术。报告了一个简短的病例史来说明治疗干预措施。
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引用次数: 0
[Use of the genogram in the day care center: how the personal and familial history provides sense to time arrested]. [在日托中心使用基因图谱:个人和家族历史如何为时间逮捕提供意义]。
Pub Date : 1995-07-01
M Laurent

This paper is about a therapeutic group created 3 years ago in our psychiatric day care unit: the genogram group. We will explain first how was born the idea of a work based on familial history and relationship, and how it was organised in practice. Then, we will speak about genogram interpretation and the different themes that the genogram can reveal: the nuclear family, the familial culture (her myths, her repeating model), the familial life cycle. We will also expose the theoretical models on which are based these themes. Finally, we will present our observations based on the experience with this group and about the characteristics and advantages of his use in institution.

这篇论文是关于三年前在我们的精神科日托中心创建的一个治疗组:基因图谱组。我们将首先解释基于家族历史和关系的作品的想法是如何产生的,以及它是如何在实践中组织起来的。然后,我们将讨论家谱的解释和家谱可以揭示的不同主题:核心家庭,家庭文化(她的神话,她的重复模式),家庭生命周期。我们还将揭示基于这些主题的理论模型。最后,我们将根据这个小组的经验,以及在机构中使用他的特点和优势,提出我们的观察。
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引用次数: 0
[Decrease in the frontal-superobasal metabolic ratio in unipolar depression]. [单极抑郁症患者额-上基底代谢率降低]。
Pub Date : 1995-07-01
A François, F Biver, S Goldman, A Luxen, J Mendlewicz, F Lotstra

Cerebral frontal glucose metabolism was investigated in 12 unipolar depressed patients and compared to these of 12 healthy volunteers using Positron Emission Tomography (PET) and (F18) fluorodeoxyglucose. The PET investigation was made in a quiet room with a dimly light and each subject remained in a resting state with closed eyes. Results show a decreased in a frontal superobasal calculated ratio in depressed patients compared to control subjects for left and for right values. This reduction indicates an imbalance between the frontal and the superobasal region. This imbalance could relate to some particular depressive symptom profile.

使用正电子发射断层扫描(PET)和氟脱氧葡萄糖(F18)对12名单极抑郁症患者的大脑额叶葡萄糖代谢进行了研究,并与12名健康志愿者进行了比较。PET检查在安静的房间里进行,光线昏暗,每个受试者闭上眼睛保持休息状态。结果显示,与对照组相比,抑郁症患者的额上基底计算比值的左值和右值有所下降。这种减少表明额叶和上基底区不平衡。这种不平衡可能与某些特定的抑郁症状有关。
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引用次数: 0
[The controversy of depression in black Africa: a study of cultural causes]. [非洲黑人抑郁症的争议:文化原因研究]。
Pub Date : 1995-07-01
V Niati, B Gilain, P Meire

Epidemiological data about depression in Africa are contradictory. Until the fifties, an almost absence of depression was reported in the studied population and from the fifties till today, a prevalence comparable to these of others continents is found. The authors discussed methodological and technical grounds susceptible to explain this controversy, with a special focus on cultural factors according to the parental and way of thinking of the Kongos in Zaïre.

关于非洲抑郁症的流行病学数据是相互矛盾的。直到20世纪50年代,研究人群中几乎没有抑郁症的报道,从50年代到今天,发现了与其他大陆相当的患病率。作者从方法论和技术的角度探讨了这一争议,并根据Zaïre中孔雀人的父母和思维方式,特别关注文化因素。
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引用次数: 0
[The biological basis of suicidal behavior: neuroendocrine and psychophysiological approach to the role of catecholamines]. [自杀行为的生物学基础:儿茶酚胺作用的神经内分泌和心理生理学研究]。
Pub Date : 1995-07-01
W Pitchot, M Hansenne, A Gonzalez Moreno, J Wauthy, M Ansseau

The current main neurochemical theories of the biological correlates of suicidal behavior principally involve the serotonergic system. Few data are available about the possible role of the catecholaminergic (noradrenergic and dopaminergic) function. In the present study, in a first part, we assessed the growth hormone (GH) response to clonidine, a selective alpha 2-adrenergic agonist, and to apomorphine, a dopaminergic agonist, in 22 DSM-III-R major depressive male inpatients with a history of suicide attempts compared to 22 age-matched major depressive inpatients without history of suicidal behavior. Hormonal responses to clonidine and apomorphine were also compared with 4.00 PM postdexamethasone cortisol levels. The two groups differed significantly in the GH peak response after apomorphine: 6.27 +/- 3.18 ng/ml in suicide attempters vs 17.40 +/- 14.87 ng/ml in nonattempters (F = 11.78, p = 0.001). There was no statistically significant difference between the two groups for GH peak responses after clonidine. Moreover, mean postdexamethasone cortisol levels did not exhibit any significant difference between suicide attempters and nonattempters. Violent and nonviolent attempters did not differ on any of the biological measures. In a second part, P300 and contingent negative variation (CNV) were recorded in 20 depressive inpatients subgrouped into suicide attempters (n = 10) and nonattempters (n = 10). The results showed a significant reduction of both P300 and CNV amplitudes in patients who attempted suicide compared to patients without history of suicide attempts. Moreover, a significant correlation was found between the Suicidal Risk scale and CNV amplitude. In conclusion, these results suggest that a dopaminergic hypoactivity as assessed by a blunted GH response to apomorphine and by a reduction of both P300 and CNV amplitudes, could be considered as a biological correlate of suicidal behavior. In contrast, noradrenergic disturbances, particularly at the level of alpha 2-adrenergic receptors, seem to play a more minor role. Moreover, DST nonsuppression cannot be considered as a biological marker of suicidal behavior.

目前关于自杀行为生物学相关性的主要神经化学理论主要涉及血清素能系统。关于儿茶酚胺能(去肾上腺素能和多巴胺能)功能的可能作用的资料很少。在本研究中,在第一部分中,我们评估了22名有自杀企图史的男性抑郁症患者的生长激素(GH)对可卡因定(一种选择性α 2-肾上腺素能激动剂)和阿波啡(一种多巴胺能激动剂)的反应,并与22名年龄匹配的无自杀行为史的重度抑郁症住院患者进行了比较。对可乐定和阿波啡的激素反应也与下午4点地塞米松后皮质醇水平进行比较。两组在阿波吗啡治疗后的GH峰值反应差异显著:自杀未遂者为6.27 +/- 3.18 ng/ml,而非自杀未遂者为17.40 +/- 14.87 ng/ml (F = 11.78, p = 0.001)。可乐定后两组GH峰值反应无统计学差异。此外,平均地塞米松后皮质醇水平在自杀未遂者和非自杀未遂者之间没有显着差异。暴力企图者和非暴力企图者在任何生物学指标上都没有差别。在第二部分中,记录了20名抑郁症住院患者的P300和偶然负变异(CNV),这些患者被分为自杀未遂者(n = 10)和非自杀未遂者(n = 10)。结果显示,与没有自杀史的患者相比,自杀未遂患者的P300和CNV幅度均显著降低。自杀风险量表与CNV幅值存在显著相关。总之,这些结果表明,通过抑制生长激素对阿波啡的反应以及P300和CNV幅度的降低来评估的多巴胺能活性低下可以被认为是自杀行为的生物学相关性。相反,去甲肾上腺素能紊乱,特别是在α 2肾上腺素能受体水平上,似乎起的作用更小。此外,DST不抑制不能被认为是自杀行为的生物学标记。
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引用次数: 0
[Retrospective study of restraining measures in a population of patients admitted under a regimen of involuntary commitment]. [在非自愿收容方案下入院的患者群体中限制措施的回顾性研究]。
Pub Date : 1995-07-01
F Dumont, M Schittecatte, G Deleu, J Wilmotte

The application of the 06-26-1990 law for the protection of mentally ill persons has confronted the psychiatrists working in general psychiatry wards with the problem of keeping up patients hospitalized against their own will and following a judiciary authority decision. Having to deal with this problem, the authors first reviewed the literature about the use of restraint techniques in psychiatry. They observed that these universally used techniques were strikingly denied in the psychiatric literature so that their accurate application was made difficult because of the lack of information about their indications, contra-indications and application modalities. Afterwards, the authors have compared the different restraint techniques in a retrospective study over a one year period among voluntarily hospitalized patients and patients admitted against their wil in application of the 06-26-1990 law. They reported that the application of the law undoubtedly increased the number of restraint but did not modify either the population characteristics of the treatment modalities. These results have to be further confirmed in a prospective study.

《1990年6月26日保护精神病患者法》的实施使在普通精神病病房工作的精神科医生面临一个问题,即病人违背自己的意愿并按照司法当局的决定继续住院。为了解决这个问题,作者首先回顾了关于在精神病学中使用约束技术的文献。他们观察到,这些普遍使用的技术在精神病学文献中被明显否认,因此由于缺乏有关其适应症、禁忌症和应用方式的信息,它们的准确应用变得困难。随后,作者在一项为期一年的回顾性研究中比较了自愿住院的患者和非自愿住院的患者在适用06-26-1990法律的情况下的不同约束技术。他们报告说,法律的适用无疑增加了限制的次数,但并没有改变治疗方式的人口特征。这些结果需要在前瞻性研究中进一步证实。
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Acta psychiatrica Belgica
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