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Advances in prostaglandin and thromboxane research最新文献

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Formation of prostaglandins in rat and rabbit kidney: effect of furosemide. 速尿对大鼠和家兔肾脏前列腺素形成的影响。
J E Vincent, F J Zijlstra
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引用次数: 0
Contribution of urine volume to the elevated urinary prostaglandin E in Bartter's syndrome and central and nephrogenic diabetes insipidus. 尿量对巴氏综合征和中枢性尿崩症及肾源性尿崩症患者尿前列腺素E升高的贡献。
M Fichman, P Zia, R Zipser

1. Urinary PGE is elevated above normal in patients with Bartter's syndrome, central and nephrogenic diabetes insipidus. 2. K+ loading, Mg2+ infusion, and water-loading-all of which increased urine volume-were associated with augmented urinary PGE in Bartter's syndrome, while fluid restriction decreased urinary PGE to normal. 3. Antidiuresis in central diabetes insipidus with DDAVP, and with indomethacin or ibuprofen in nephrogenic diabetes insipidus, is associated with a decrease in urinary PGE. 4. High urine volume may be a contributing factor to the elevated urinary PGE in Bartter's syndrome, central and nephrogenic diabetes insipidus.

1. 巴氏综合征、中枢性尿崩症和肾源性尿崩症患者尿PGE高于正常水平。2. K+负荷、Mg2+输注和水负荷——所有这些都增加了尿量——与Bartter综合征尿PGE增加有关,而液体限制使尿PGE降至正常。3.中枢性尿崩症患者应用DDAVP抗利尿,肾源性尿崩症患者应用吲哚美辛或布洛芬抗利尿与尿PGE降低相关。4. 高尿量可能是巴特氏综合征、中枢性尿崩症和肾源性尿崩症患者尿PGE升高的一个因素。
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引用次数: 0
Dissimilar effects of PGE1 and PGE2 on myocardial infarct size after coronary occlusion in conscious dogs. PGE1和PGE2对清醒犬冠状动脉闭塞后心肌梗死大小的不同影响。
B I Jugdutt, G M Hutchins, B H Bulkley, L C Becker
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引用次数: 0
Modulation of peritoneal transport rates by prostaglandins. 前列腺素对腹膜转运率的调节。
J F Maher, P Hirszel, M Lasrich
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引用次数: 0
Effect of prostaglandins E1 and E2 on rabbit pulmonary artery and aorta strips. 前列腺素E1、E2对家兔肺动脉、主动脉条带的影响。
S Kitamura, Y Ishihara, K Kosaka
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引用次数: 0
Indications and pharmacological effects of therapy with prostaglandin E1 in the newborn. 前列腺素E1治疗新生儿的适应症及药理作用。
J G Schöber, M Kellner, R Mocellin, G Schumacher, K Bühlmeyer
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引用次数: 0
Metabolism of 3H-arachidonic acid in male dog lung in vitro using a perfusion system designed to mimic physiological conditions. 利用模拟生理条件的灌注系统研究3h -花生四烯酸在雄性狗肺中的体外代谢。
P Barnes, C T Dollery, C N Hensby
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引用次数: 0
Time-synchronized activation of lipolysis and fatty acids reacylation by bradykinin and angiotensin II in the perfused rabbit kidney. 缓激肽和血管紧张素II对灌注兔肾脏脂肪分解和脂肪酸再酰化的时间同步激活。
A Raz, M Schwartzman

BK and AII administered to the isolated perfused rabbit kidney activate two sequential enzymatic processes: 1) a selective release of the PG precursor, AA with concomitant, partial conversion of arachidonate to PGE2. 2) Activation of a reacylation process which leads to decreased release of all fatty acids in the perfusate. There is a lag time of approximately 1 min between initial activation of the arachidonate-specific deacylation reaction that is coupled to PG generation, and subsequent activation of the reacylation process.

BK和AII给予离体灌注兔肾激活两个顺序的酶促过程:1)选择性释放PG前体AA,同时花生四烯酸酯部分转化为PGE2。2)再酰化过程的激活,导致灌注液中所有脂肪酸的释放减少。在与PG生成耦合的花生四烯酸酯特异性去酰化反应的初始激活和随后的再酰化过程的激活之间存在大约1分钟的滞后时间。
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引用次数: 0
Thromboxane B2 production and lipid peroxidation in human blood platelets. 血小板中血栓素B2的产生和脂质过氧化。
L C Best, P B Jones, M B McGuire, R G Russell
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引用次数: 0
The VX-2 carcinoma: humoral effects and arachidonic acid metabolism. VX-2癌:体液效应和花生四烯酸代谢。
W C Hubbard, A Hough, A R Brash, R M Johnson, J A Oates
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引用次数: 0
期刊
Advances in prostaglandin and thromboxane research
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