Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.1.40
S. Choi, Sung-Hoon Chung, Kyung-Suk Lee, C. Bae, Y. Rha
Purpose: Eosinophil-derived neurotoxin (EDN) is not the only a marker for eosinophil activation, but also acts as an alarm protein. Very few studies have examined the potential role of eosinophils in the development of bronchopulmonary dysplasia (BPD). This study aims to address the roles of eosinophil and EDN in the early phase of BPD development. Methods: Patients were preterm neonates with respiratory distress syndrome (RDS) born at 36 weeks of gestation or less. Blood and urine samples were collected to measure total eosinophil count in the blood, serum eosinophil cationic protein (ECP), serum EDN, and urinary EDN during the first week of life. Results: Fifty-two preterms were recruited, of whom 43 infants were analyzed. Comparisons were made between the RDS (n=16) and non-RDS groups (n=27) and between the BPD (n=6) and non-BPD groups (n=26). There were no differences between RDS and non-RDS group in total eosinophil count, serum ECP, serum EDN, or urinary EDN, except when compared by gestational age, birth weight and prenatal dexamethasone use. Urinary EDN was increased significantly in the BPD group compared to the non-BPD group. Conclusion: We demonstrated the roles of eosinophil and EDN in the development of BPD and suggest that urinary EDN may be utilized as a noninvasive factor predicting the development of BPD. ( Allergy Asthma Respir Dis 2022;10:40-44 )
{"title":"Eosinophil activation markers in blood and urine in preterms developing bronchopulmonary dysplasia","authors":"S. Choi, Sung-Hoon Chung, Kyung-Suk Lee, C. Bae, Y. Rha","doi":"10.4168/aard.2022.10.1.40","DOIUrl":"https://doi.org/10.4168/aard.2022.10.1.40","url":null,"abstract":"Purpose: Eosinophil-derived neurotoxin (EDN) is not the only a marker for eosinophil activation, but also acts as an alarm protein. Very few studies have examined the potential role of eosinophils in the development of bronchopulmonary dysplasia (BPD). This study aims to address the roles of eosinophil and EDN in the early phase of BPD development. Methods: Patients were preterm neonates with respiratory distress syndrome (RDS) born at 36 weeks of gestation or less. Blood and urine samples were collected to measure total eosinophil count in the blood, serum eosinophil cationic protein (ECP), serum EDN, and urinary EDN during the first week of life. Results: Fifty-two preterms were recruited, of whom 43 infants were analyzed. Comparisons were made between the RDS (n=16) and non-RDS groups (n=27) and between the BPD (n=6) and non-BPD groups (n=26). There were no differences between RDS and non-RDS group in total eosinophil count, serum ECP, serum EDN, or urinary EDN, except when compared by gestational age, birth weight and prenatal dexamethasone use. Urinary EDN was increased significantly in the BPD group compared to the non-BPD group. Conclusion: We demonstrated the roles of eosinophil and EDN in the development of BPD and suggest that urinary EDN may be utilized as a noninvasive factor predicting the development of BPD. ( Allergy Asthma Respir Dis 2022;10:40-44 )","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"47 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88498618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.2.105
Jeongmin Lee, H. Kim, K. Jeong, Se-Ah Jeon, Sooyoung Lee
{"title":"Additional diagnostic value of component resolved diagnosis in children with kiwifruit allergy","authors":"Jeongmin Lee, H. Kim, K. Jeong, Se-Ah Jeon, Sooyoung Lee","doi":"10.4168/aard.2022.10.2.105","DOIUrl":"https://doi.org/10.4168/aard.2022.10.2.105","url":null,"abstract":"","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"56 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83893491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.1.55
J. Jeong, Y. Jang
{"title":"Diagnosis and treatment of immunoglobulin G subclass deficiency in a school-age child with recurrent wheezing","authors":"J. Jeong, Y. Jang","doi":"10.4168/aard.2022.10.1.55","DOIUrl":"https://doi.org/10.4168/aard.2022.10.1.55","url":null,"abstract":"","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"94 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81753486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.4.202
Kwang Hee Kim, D. Kim, Young Youn, Juyoung Lee, H. Kim
{"title":"Pattern and risk factor of lower respiratory illness in children who survived meconium aspiration syndrome","authors":"Kwang Hee Kim, D. Kim, Young Youn, Juyoung Lee, H. Kim","doi":"10.4168/aard.2022.10.4.202","DOIUrl":"https://doi.org/10.4168/aard.2022.10.4.202","url":null,"abstract":"","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"16 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78387897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.4.215
Sun-Young Lee, M. Kim, Jin-A Jung, S. Rha, Chae-Ku Jo
{"title":"A case of cow’s milk-induced eosinophilic enterocolitis masquerading as necrotizing enterocolitis in a preterm infant with extremely low birth weight","authors":"Sun-Young Lee, M. Kim, Jin-A Jung, S. Rha, Chae-Ku Jo","doi":"10.4168/aard.2022.10.4.215","DOIUrl":"https://doi.org/10.4168/aard.2022.10.4.215","url":null,"abstract":"","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"65 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76796127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.4.219
H. Yeh, M. Lim, H. Seo, E. Lee, Joonggon Kim, H. Yum
{"title":"Severe asthma exacerbation associated with COVID-19 in children: A case report","authors":"H. Yeh, M. Lim, H. Seo, E. Lee, Joonggon Kim, H. Yum","doi":"10.4168/aard.2022.10.4.219","DOIUrl":"https://doi.org/10.4168/aard.2022.10.4.219","url":null,"abstract":"","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"80 2 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90939710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.3.172
C. Park, Eun-Jung Jo, Mi-Yeong Kim, Y. Nam, Seung-Eun Lee, G. Choi, Y. Jeong, Hee-Kyoo Kim, Jae-Won Oh, Hye-Kyung Park
{"title":"Change in sensitization to inhalant allergens in adults with respiratory allergic disease in Busan and Gyeongsangnam-do province","authors":"C. Park, Eun-Jung Jo, Mi-Yeong Kim, Y. Nam, Seung-Eun Lee, G. Choi, Y. Jeong, Hee-Kyoo Kim, Jae-Won Oh, Hye-Kyung Park","doi":"10.4168/aard.2022.10.3.172","DOIUrl":"https://doi.org/10.4168/aard.2022.10.3.172","url":null,"abstract":"","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"187 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73920655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.2.123
Yeseul Lee, J. Hwang, Su Kyung Kim, Mi Jin Kim, T. Y. Jeon, Jihyun Kim, K. Ahn, Jiwon Kim
{"title":"A case of food-induced acute pancreatitis in a child with egg white allergy","authors":"Yeseul Lee, J. Hwang, Su Kyung Kim, Mi Jin Kim, T. Y. Jeon, Jihyun Kim, K. Ahn, Jiwon Kim","doi":"10.4168/aard.2022.10.2.123","DOIUrl":"https://doi.org/10.4168/aard.2022.10.2.123","url":null,"abstract":"","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"20 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81732552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4168/aard.2022.10.1.15
Jin-Sung Park, Ja Kyoung Kim, Jae-Woo Kwon
Purpose: Anaphylaxis may be life-threatening, and thus requires early recognition and a rapid response. We investigated current demands imposed by anaphylaxis and the responses of pediatric and youth educational institutions. We surveyed school nurses and childcare teachers in Gangwon-do Province, South Korea. Methods: The online survey featured 2 questionnaires: one exploring demands imposed by anaphylaxis and the current response status and the other evaluating awareness of anaphylaxis among school nurses and childcare teachers. Results: A total of 105 school nurses and 263 childcare teachers responded, of whom 16.2% and 1.9% reported that they had encountered anaphylaxis at work, and 6.7% and 11.0% had epinephrine auto-injectors (EAIs) available, respectively. Furthermore, 7.6% of school nurses and 3.0% of childcare teachers had been requested by parents to obtain institutional EAIs. Screening for anaphylaxis at the beginning of each school year was performed in 81.9% of schools and 41.1% of childcare institutions, and 55.2% of schools and 44.5% of childcare institutions had formulated action plans for anaphylaxis. Anaphylaxis education had been received by 72.4% of school nurses and 38.8% of childcare teachers. However, anaphylaxis awareness and coping skills seemed to be lacking in most participants. Conclusion: Given the nontrivial numbers of pediatric patients with anaphylaxis and thus the demand for assistance, the lack of institutional prevention and management systems (screening, action plans, and coping skills) is of concern. In addition to increasing teacher awareness, institutional changes are required. ( Allergy Asthma Respir Dis 2022;10:15-21 )
{"title":"Anaphylaxis-related interventional demand and the response status of pediatric and youth educational institutions in Gangwon-do Province, South Korea: A school nurse and childcare teacher survey","authors":"Jin-Sung Park, Ja Kyoung Kim, Jae-Woo Kwon","doi":"10.4168/aard.2022.10.1.15","DOIUrl":"https://doi.org/10.4168/aard.2022.10.1.15","url":null,"abstract":"Purpose: Anaphylaxis may be life-threatening, and thus requires early recognition and a rapid response. We investigated current demands imposed by anaphylaxis and the responses of pediatric and youth educational institutions. We surveyed school nurses and childcare teachers in Gangwon-do Province, South Korea. Methods: The online survey featured 2 questionnaires: one exploring demands imposed by anaphylaxis and the current response status and the other evaluating awareness of anaphylaxis among school nurses and childcare teachers. Results: A total of 105 school nurses and 263 childcare teachers responded, of whom 16.2% and 1.9% reported that they had encountered anaphylaxis at work, and 6.7% and 11.0% had epinephrine auto-injectors (EAIs) available, respectively. Furthermore, 7.6% of school nurses and 3.0% of childcare teachers had been requested by parents to obtain institutional EAIs. Screening for anaphylaxis at the beginning of each school year was performed in 81.9% of schools and 41.1% of childcare institutions, and 55.2% of schools and 44.5% of childcare institutions had formulated action plans for anaphylaxis. Anaphylaxis education had been received by 72.4% of school nurses and 38.8% of childcare teachers. However, anaphylaxis awareness and coping skills seemed to be lacking in most participants. Conclusion: Given the nontrivial numbers of pediatric patients with anaphylaxis and thus the demand for assistance, the lack of institutional prevention and management systems (screening, action plans, and coping skills) is of concern. In addition to increasing teacher awareness, institutional changes are required. ( Allergy Asthma Respir Dis 2022;10:15-21 )","PeriodicalId":7548,"journal":{"name":"Allergy, Asthma & Respiratory Disease","volume":"26 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81850443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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