Archives de l'Institut Pasteur d'Algerie. Institut Pasteur d'Algerie最新文献

It concerns comparative studies between two children groups: One group who had previous RAA. A second group who had anginas only. This work shows the interest to associate two streptococcal serologic tests (ASLO, ASD) in order to increase the number of recent diagnostic streptococcal infectious. The remaining immunity is missing in children less than 5 years old; more than 50% of above 10 years an antistreptococcal answer although they have not streptococcus infections presently.

During 1967 to 1985, three cases of listeriosis were reported in Algeria; at that time Listeria monocytogenes caused several thousand cases of meningitis and sepsis in the world. In order to determine the frequency and bacteriologic characteristics of strain isolated in Algeria, a prospective investigation was carried from 1985 to 1989 in humans and animals samples. Sensitivity tests to antibiotics (MIC) point out that all isolates strains are resistant to cephalosporins (first and third generation), but are susceptible to Ampicillin and Gentamicin which ought to constitute the treatment basis of listeriosis.

A Behring's production protocol of antigenic suspensions O and H of Salmonella typhi has been studied. The object of this study has been the Search of optimal conditions of cultivation and their exploitation on fermentor. A fermentation using the I.P.A culture medium has been realized to compare its results with that obtained using Behring's culture medium (B.C.M). The optimal cultivation conditions obtained are a waving rate of 400 tr/mn, a pH of 7.6 and an important air flow. Relating to nutritious constituents, the adequate glucose concentration is about 8g/1 and it seems better to replace meat extract by yeast extract. Comparatively to I.P.A culture medium, one of the most important advantage of Behring's culture medium modified reside in the conservation of the antigenicity of Salmonella typhi.

The authors report 285 cases of visceral leishmaniasis recorded over a 6 year-period from 1985-1990 in the Wilaya of Tizi-Ouzou (Grande Kabylie). The authors report a resurgence of this disease during the last years, with a 5 human cases per 100,000 annual prevalence and a 6 per cent of rate death, the most active part of mediterranean area appears to be the region of Grand-Kabylie. A control program in the Wilaya of Tizi-Ouzou is proposed.

Yersinia enterocolitica has been researched in 200 samples of human stools, 40 animals excrements, 38 specimens of soils and 46 of water; the microorganism has been recovered in respectively 3.5%, 10%, 10.5% and 26% out of the total of samples examined; the strains isolated belong to different Wauter's biotype scheme but the biotype 1 is the most predominant except in soil samples. None of biotype 2 and 4, admitted to be adapted to man, has been isolated from human stools. We think that the notion of adaptation of a given biotype to a given host must be reviewed. These data, although they demonstrate the existence of yersinia enterocolitica in Algeria, because of the small number of samples examined, do not reflect exactly the real incidence of the infection caused by this microorganism.

Nalidixic acid and three fluoroquinolones were tested on 389 strains belonging to 13 bacterial species, all isolated in Algeria. Ofloxacin, norfloxacin and pefloxacin have the same activities on E. coli, Acinetobacter and S. aureus. Norfloxacin has the best activity on Proteus, Enterobacter, Shigella and Klebsiella. Norfloxacin and ofloxacin have the same activities on S. typhi, Salmonella and choleric Vibrio. Norfloxacin has the same activity than pefloxacin on P. aeruginosa. It is necessary to prescribe a quinolone in the right way and to consider the pharmacokinetic properties.

We report here an isolation of bacteria genus Nocardia, Nocardia farcinica, in a dialysis liquid of a renal insufficiency patient treated by continuous ambulatory peritoneal dialysis (C.A.P.D.). Real peritonitis was due to infection with this bacteria, eliminated after an adapted antibiotherapy. This observation is interesting first because of the rare occurrence of Nocardia's peritonitis in the patients on CAPD, and secondly in relation with the species of Nocardia, Nocardia farcinica, less known than Nocardia asteroides but not less pathogenic.

A epidemic of enteric pathogens bacteria occurred in december 1989 and caused two deaths in a nursery. There were many investigations between december 1989 and september 1990 trying to clarify this epidemic context. A new serovar of Salmonella had for the first time been isolated from babies' feces in Algeria. Salmonella m'bandaka has been identified in more than 50% of analysis. During an hygienic investigation in this nursery the above Salmonella m'bandaka was isolated in a open physiologic solution flask.

The serovars evolution of 3340 Salmonella strains isolated from 1986 to 1990 in Algeria have been studied. Among Salmonella responsible for typhoid-paratyphoid fevers, 98% are S. typhi; the prevalence of this serovar is observed every year. Among the other Salmonella, 50 different serovars have been isolated from 1986 to 1990. The predominant serovars change every year but 98% out of the total belong to 8 groups of Kauffmann White scheme; the most frequent are: groups O: 6, 7-O: 8-O: 4 and O: 9.