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Some comments on the efficiency and simulation of Thailand's Chiang Mai University model for COVID-19 mass vaccination hub 对泰国清迈大学新型冠状病毒大规模疫苗接种中心模型效率和模拟的几点评价
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.10.028
Salvatore Chirumbolo PhD , Umberto Tirelli MD
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引用次数: 0
Information for Readers
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/S0196-6553(24)00913-1
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引用次数: 0
The epidemiology of midline-associated bloodstream infections in an urban health care system 城市医疗系统中线相关血流感染的流行病学。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.10.037
Rebecca Choudhury MD , Jordan Ehni CIC, MPH , Waleed Javaid MD, FACP, FIDSA, FSHEA , Mateen Jangda BS , Itay Rabinovitz MD , Nikita Ekhelikar MD , Bernard C. Camins MD, MSc
This study sought to determine the incidence and characteristics of midline-associated bloodstream infections (MABSI) at an urban health system during the COVID-19 pandemic. A MABSI rate similar to the central line-associated bloodstream infection rate was found. A large number of MABSI were caused by Staphylococcus spp and Enterococcus spp, as has previously been reported for central line-associated bloodstream infection. Patients with MABSI had high in-hospital mortality rates.
本研究旨在确定 COVID-19 大流行期间某城市医疗系统中线相关血流感染 (MABSI) 的发病率和特征。结果发现,中线相关血流感染(MABSI)率与中线相关血流感染(CLABSI)率相似。大量的 MABSI 由葡萄球菌属和肠球菌属引起,这与之前报告的 CLABSI 相同。MABSI 患者的院内死亡率很高。
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引用次数: 0
Impact of COVID-19 pandemic on reusable device precleaning training for front-line staff COVID-19 大流行对前线员工可重复使用设备预清洁培训的影响。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.10.003
Josephine Fox MPH, BSN, RN, CIC, FAPIC , Lydia Grimes-Jenkins MSN, BA, RN, CIC, FAPIC , Heather Gasama MPH , Ashley Lloyd BSN, RN, CIC , Helen Wood MA, BSN, RN, CIC, FAPIC , Satish Munigala MBBS, PhD , David K. Warren MD, MPH
High-level disinfection and sterilization are complex processes, requiring initial and ongoing training of frontline staff.1 A key component of appropriate disinfection and sterilization is point-of-use precleaning performed by front-line staff. Our facility implemented an annual hospital-wide education and competency program for staff that perform precleaning of reusable medical devices.
高级消毒和灭菌是复杂的过程,需要对一线员工进行初始和持续培训。1 适当消毒和灭菌的一个关键组成部分是由一线员工进行使用点预清洁。我们的医疗机构针对执行可重复使用医疗器械预清洁工作的员工实施了全院范围的年度教育和能力培训计划。
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引用次数: 0
Infection Prevention and Control Response and Escalation Framework: Evaluation and application beyond a pandemic 感染预防与控制响应和升级框架--大流行后的评估和应用。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.10.036
Kathy Dempsey MNSc, CICP-E , Susan Jain MIPH, PhD, CICP-E , Patricia Bradd PhD , Kate Clezy MBBS, FRACP , David Greenfield PhD

Background

The COVID-19 pandemic resulted in constant changes to Infection Prevention and Control (IPAC) recommendations, impacting clinician capacity to stay up to date. The COVID-19 IPAC Response and Escalation Framework (IPAC Framework), rarely reported or evaluated was developed to provide scalable IPAC guidance during the pandemic to health care in New South Wales (NSW), Australia.

Methods

Using a thematic analysis approach, a qualitative study using an online, cross-sectional survey comprising 27 questions was sent to 248 key stakeholders. Participants were health workers with broad clinical and system representation with responsibilities for risk assessment, communicating, implementing, or monitoring the IPAC Framework.

Results

The IPAC Framework provided a useful IPAC tool for the management of COVID-19 as perceived by 93% of respondents. The overwhelming majority (91%) reported the Framework provided enough information on IPAC strategies needed for COVID-19 that were aligned with transmission risk. Resources supporting the IPAC Framework were reported by most respondents (84%) as being widely accepted as the authoritative guidance.

Conclusions

An IPAC Framework is perceived as invaluable by clinicians and administrators to manage IPAC requirements in health care during a pandemic. The IPAC Framework can be applied more generally to support ongoing IPAC requirements.
背景:COVID-19 大流行使感染预防与控制 (IPAC) 建议发生了快速而频繁的变化,临床医生很难及时了解最新的要求和指南。COVID-19 IPAC 响应和升级框架(IPAC 框架)的制定是为了在大流行期间为澳大利亚新南威尔士州的医疗保健机构提供可扩展的 IPAC 指导。此类框架在大流行期间或非大流行期间的使用情况很少有报道和评估:采用专题分析方法,向 248 名主要利益相关者发送了一份包含 27 个问题的在线横截面调查问卷,进行了一项定性研究。参与调查的人员都是卫生工作者,他们在临床和系统中具有广泛的代表性,负责风险评估、沟通、实施和/或监控 IPAC 框架:93%的受访者认为 IPAC 框架为 COVID-19 的管理提供了有用的 IPAC 工具。绝大多数受访者(91%)表示,该框架提供了有关 COVID-19 所需的 IPAC 战略的足够信息,这些战略与传播风险相一致。大多数受访者(84%)表示,支持 IPAC 框架的资源被广泛接受为权威指南:结论:临床医生和管理人员认为 IPAC 响应和升级框架在大流行期间管理医疗保健中的 IPAC 要求方面非常有用。IPAC 框架可以更广泛地应用于支持持续的 IPAC 要求。
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引用次数: 0
Response to the letter to the editor regarding “The impact of a novel color additive for disinfectant wipes on room cleanliness and turnover time” 回复给编辑关于“一种新型颜色添加剂用于消毒湿巾对房间清洁度和周转时间的影响”的信。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.10.033
Olayinka Oremade MD, MPH, CIC , Barbara Odac MD , Jinzy George MD , Frederick Browne MD, MBA, FACP, GSHEA, FASAM
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引用次数: 0
Prevalence of infection and reinfection among health care workers in a hospital of Northern China between BA.5/BF.7 and XBB.1.5 wave 华北某医院医护人员在BA.5/BF.7波和XBB.1.5波之间华北某医院医护人员的感染率和再感染率。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.08.009
Xue-Dong Song MM , Hui-Xia Gao MM , Hao Tan MB , Yan-Yan Xie MB , Xin Zhang MM , Chen-Min Zhang MB , Yu-Ling Wang MM , Er-Hei Dai MD

Background

To analyze the epidemiological characteristics of the SARS-CoV-2 infection and reinfection associated with the emergence of Omicron variant in Healthcare workers (HCWs).

Methods

We enrolled 760 HCWs who received 2-4 vaccination doses of COVID-19 and followed by BA.5/BF.7 and/or XBB.1.5 breakthrough infections between December 2022 and July 2023. Serum sample from each individual were collected approximately 1,3 and 6 months after last exposure. IgM, IgG and Total antibodies against SARS-CoV-2 were measured by chemiluminescent immunoassay. Meanwhile, we created an Enterprise WeChat link for HCWs to self-report SARS-CoV-2 infections, symptoms and post COVID-19 conditions.

Results

Our study revealed that the reinfection rate among HCWs reached 26.1%. The main symptoms were fever (91.2% vs 60.1%), cough (78.8% vs 58.0%), and sore throat (75.4% vs 59.6%) during infection and reinfection in Omicron BA.5/BF.7 and XBB.1.5 wave, and the interval for reinfection ranged from 91 to 210 days (median 152). Fatigue (23.6%), memory loss (18.8%) and coughing (18.6%) were the most prevalent long COVID symptoms, with a higher prevalence among female HCWs.

Conclusions

HCWs reinfection with SARS-CoV-2 causes milder symptoms, but high reinfection rate and short intervals. Strengthen infection prevention and control is crucial to mitigating infection risk and improving health services.
背景:在COVID-19大流行期间,医护人员(HCWs)作为前线响应者发挥着至关重要的作用。本研究旨在分析医护人员首次感染 SARS-CoV-2 和再次感染与 Omicron 变种出现相关的流行病学特征:我们招募了760名在2022年12月至2023年7月期间接种过2-4剂COVID-19疫苗并随后发生BA.5/BF.7和/或XBB.1.5突破性感染的HCW。每个人的血清样本都是在最后一次暴露后大约 1、3 和 6 个月采集的。通过化学发光免疫测定法测定 SARS-CoV-2 的 IgM、IgG 和总抗体。与此同时,我们还创建了一个企业微信链接,供HCW自我报告SARS-CoV-2感染、症状和COVID-19后的情况:结果:我们的研究显示,HCW 的再感染率达到 26.1%。在 Omicron BA.5/BF.7 和 XBB.1.5 波感染和再感染期间,主要症状是发烧(91.2% 对 60.1%)、咳嗽(78.8% 对 58.0%)和咽喉痛(75.4% 对 59.6%),再感染间隔时间从 91 天到 210 天不等(中位数为 152 天)。乏力(23.6%)、记忆力减退(18.8%)和咳嗽(18.6%)是高危职业工人最常见的长期 COVID 症状,女性高危职业工人的发病率更高:结论:HCW 再感染 SARS-CoV-2 后症状较轻,但再感染率高且间隔时间短。加强预防策略、保护和培训对于降低高危卫生工作者的感染风险和改善卫生服务至关重要。
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引用次数: 0
Development and implementation of learning collaboratives for infection prevention and control education in long-term care facilities 长期护理机构感染预防与控制教育学习合作组织的发展与实施。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.09.021
Cindy Prins PhD, MPH, CIC , Mishal Khan MHA , Nicole M. Marlow PhD, MSPH , Avery Bollinger MS , Cassandra L. Johnson RN, MPH , Jamie L. Pomeranz PhD , Sally M. Bethart DNP, APRN, CNE , Kartikeya Cherabuddi MD,FIDSA , Ann L. Horgas PhD, RN , Veena Venugopalan PharmD , Duzgun Agdas PhD , Chang-Yu Wu PhD, MS , Antarpreet Singh Jutla PhD, MSc, MTech , Argentina Charles MPH, CIC , F. Lee Revere PhD, MS
Infections in long-term care facilities pose a critical challenge, with 1 to 3 million serious infections annually and up to 380,000 associated deaths. The vulnerability of aging populations and inadequate infection prevention and control programs underscore the need for intervention. This initiative provided tailored continuing education through 8 virtual learning collaboratives serving 541 infection preventionists. The project also developed 9 infection prevention and control toolkits and a manual to further support long-term care facilities' infection prevention efforts.
长期护理机构(LTCF)中的感染是一项严峻的挑战,每年有 100 万到 300 万例严重感染,相关死亡人数高达 38 万。老龄人口的脆弱性和感染预防与控制 (IPC) 计划的不足凸显了干预的必要性。该计划通过八个虚拟学习合作项目,为 541 名感染预防专家提供有针对性的继续教育。该项目还开发了九个 IPC 工具包和一本手册,以进一步支持 LTCF 的感染预防工作。
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引用次数: 0
Facility-level antibiotic prescribing rates and the use of antibiotics among nursing home residents 养老院居民的抗生素处方率和抗生素使用情况。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.10.007
Quynh T. Vo PhD , Farzad Noubary PhD , Brandon Dionne PharmD , Shira Doron MD , Benjamin Koethe MPH , Becky A. Briesacher PhD

Background

The high frequency of antibiotic use in US nursing homes is a public health concern. Facility-level prescribing patterns may provide a measure for antibiotic stewardship targeting.

Methods

An analysis of 2018-2019 data from linked files from the Centers for Medicaid and Medicare was conducted. Multilevel generalized linear models were used to calculate odds ratios for antibiotic receipt for calendar year 2019 using the 2018 facility prescribing rate.

Results

In 2019, 186,274 (19%) residents were prescribed an antibiotic. The most frequently prescribed class of antibiotics was cephalosporins (26%), and the average duration of antibiotic use was 9 days. Residents who were dually eligible for Medicare and Medicaid had 37% increased odds of antibiotic receipt (all adjusted odds ratio (aOR): 1.37, 95% confidence interval [CI]: 1.35, 1.39). The 2018 facility prescribing rate was associated with 14% increased odds of antibiotic receipt in 2019 in NHs in the medium (11.9%-20.2%) prescribing category (all aOR: 1.14, 95% CI: 1.11, 1.17) and 36% increased odds of antibiotic receipt in NHs in the high (> 20.3%) prescribing category (all aOR: 1.36, 95% CI: 1.32, 1.40) when compared with the lowest (0%-11.8%) prescribing category.

Conclusions

Antibiotic stewardship strategies should target nursing homes with high antibiotic prescribing rates and high populations of dually eligible patients to improve care in this population.
背景:美国养老院的抗生素使用频率很高,这是一个公共卫生问题,也是抗菌药物管理工作的目标。设施层面的处方模式可为抗生素管理目标的确定提供衡量标准:对来自医疗补助中心和医疗保险中心的四个链接文件中的 2018 年和 2019 年数据进行了分析。采用多层次广义线性模型,在控制设施和个人水平因素的情况下,使用 2018 年设施处方率计算 2019 日历年接受抗生素的几率比:2019年,186274名(19%)研究居民被处方抗生素。最常处方的抗生素类别是头孢菌素类(26%),抗生素的平均使用时间为 9 天。符合医疗保险和医疗补助双重资格的居民接受抗生素治疗的几率增加了 37%(全部 aOR:1.37,95%CI:1.35,1.39)。与最低(0-11.8%)处方类别相比,2018 年设施处方率与中等(11.9-20.2%)处方类别的养老院在 2019 年接受抗生素的几率增加 14% 相关(所有 aOR:1.14,95%CI:1.11,1.17),与高处方类别(>20.3%)的养老院接受抗生素的几率增加 36%相关(所有 aOR:1.36,95%CI:1.32,1.40):结论:抗生素管理策略应针对抗生素处方率高、双重资格患者多的养老院,以改善该人群的护理。
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引用次数: 0
Atmospheric CO2 monitoring to identify zones of increased airborne pathogen transmission risk in hospital settings 通过大气二氧化碳监测来确定医院环境中空气传播病原体风险增加的区域。
IF 3.8 3区 医学 Q2 INFECTIOUS DISEASES Pub Date : 2025-02-01 DOI: 10.1016/j.ajic.2024.10.001
Andrew P. Shoubridge PhD , Amanda Brass PhD , Levi Elms BHSc(Hons) , Sarah K. Sims BSc(Hons) , Angela Anderson MSN , Dylan Mordaunt PhD , Maria Crotty PhD , Lito E. Papanicolas PhD , Steven L. Taylor PhD , Geraint B. Rogers PhD
Measures to reduce airborne pathogen transmission in health care settings, such as increased air exchange, air decontamination, and reductions in peak occupancy, can be expensive and disruptive, particularly when employed in an untargeted manner. We report the empirical identification of high transmission risk zones in a tertiary hospital, using carbon dioxide-based assessments of air exchange. This rapid, cost-effective, and unobtrusive approach led to the targeted remediation of a high transmission risk zone.
在医疗机构中减少空气传播病原体的措施,如增加空气交换、空气净化和减少高峰占用率等,可能既昂贵又具有破坏性,尤其是在没有针对性的情况下。我们报告了利用基于二氧化碳的空气交换评估对一家三级医院的高传播风险区进行的实证识别。这种快速、经济、无干扰的方法可对高传播风险区进行有针对性的补救。
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引用次数: 0
期刊
American journal of infection control
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