C Dao, J L Harousseau, C de Carbonniéres, J Bousser, G Bilski-Pasquier
Screening for red cell defects, and exploration of cellular and humoral immunity has been performed in 33 patients : 31 had agnogenic myelosclerosis with myeloid metaplasia, 3 had polycythemia vera with secondary myelosclerosis. No patient had the biological abnormalities characteristical of paroxysmal nocturnal hemoglobinuria (Marchiafava-Micheli). In 19 out of 21 cases, red cells had antigen i on their membrane, thus suggesting that splenic erythropoiesis could give rise to immature erythrocytes. Two patients had a monoclonal dysglobulinemia, 5 a positive Coombs test, 6 a rhumatoid factor in the serum, 3 antitissue antibodies, 1 LE cells, 3 a positive Paul-Bunnel-Davidsohn test without mononucleosis, 11 a negative skin test. Implications of the uncommon occurrence of these dissorders are discussed.
{"title":"[Erythrocytic and immunologic abnormalities in myeloid splenomegaly].","authors":"C Dao, J L Harousseau, C de Carbonniéres, J Bousser, G Bilski-Pasquier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Screening for red cell defects, and exploration of cellular and humoral immunity has been performed in 33 patients : 31 had agnogenic myelosclerosis with myeloid metaplasia, 3 had polycythemia vera with secondary myelosclerosis. No patient had the biological abnormalities characteristical of paroxysmal nocturnal hemoglobinuria (Marchiafava-Micheli). In 19 out of 21 cases, red cells had antigen i on their membrane, thus suggesting that splenic erythropoiesis could give rise to immature erythrocytes. Two patients had a monoclonal dysglobulinemia, 5 a positive Coombs test, 6 a rhumatoid factor in the serum, 3 antitissue antibodies, 1 LE cells, 3 a positive Paul-Bunnel-Davidsohn test without mononucleosis, 11 a negative skin test. Implications of the uncommon occurrence of these dissorders are discussed.</p>","PeriodicalId":76247,"journal":{"name":"Nouvelle revue francaise d'hematologie; blood cells","volume":"18 3","pages":"619-26"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11802595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Five year trial of quality control in hematology from the practitioner's point of view. Future perspectives in the plan for the new biological law (proceedings)].","authors":"A Leblanc","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76247,"journal":{"name":"Nouvelle revue francaise d'hematologie; blood cells","volume":"18 3","pages":"668-70"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11805259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In 70 patients with clinical stage II, III or IV Hodgkin's disease, 31 were found to have skeletal involvement. The value of the bone scanning in the demonstration of osseous and marrow lesions is emphasized : scanning enabled localised marrow involvement in 24 patients to be detected and could be used as a guide for the biopsy needle in 11 cases. The histopathological features of marrow involvement by Hodgkin's disease are described. In view of the better knowledge of the frequency of splenic, skeletal or hepatic involvement, the preferential involvement of a particular organ in disseminated diseases is discussed. The high frequency of splenic involvement could be due to the inadequacy of the methods detecting hepatic or marrow involvement, although the nature of the disease could also be a factor.
{"title":"[Skeletal and medullary involvement in Hodgkin's disease].","authors":"A Ferrant, J Rodhain, J L Michaux, G Sokal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 70 patients with clinical stage II, III or IV Hodgkin's disease, 31 were found to have skeletal involvement. The value of the bone scanning in the demonstration of osseous and marrow lesions is emphasized : scanning enabled localised marrow involvement in 24 patients to be detected and could be used as a guide for the biopsy needle in 11 cases. The histopathological features of marrow involvement by Hodgkin's disease are described. In view of the better knowledge of the frequency of splenic, skeletal or hepatic involvement, the preferential involvement of a particular organ in disseminated diseases is discussed. The high frequency of splenic involvement could be due to the inadequacy of the methods detecting hepatic or marrow involvement, although the nature of the disease could also be a factor.</p>","PeriodicalId":76247,"journal":{"name":"Nouvelle revue francaise d'hematologie; blood cells","volume":"18 3","pages":"545-54"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11802586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[First thoughts on regional quality control in hemocytology and hemostasis (proceedings)].","authors":"S Guibaud, L Monnet","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76247,"journal":{"name":"Nouvelle revue francaise d'hematologie; blood cells","volume":"18 3","pages":"665-7"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11802594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytochemical study of the cell colonies from agar culture of normal bone marrow and of peripheral blood from patients with chronic myeloid leukemia.","authors":"M Grande, V Liso","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76247,"journal":{"name":"Nouvelle revue francaise d'hematologie; blood cells","volume":"18 3","pages":"563-71"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11485806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Testing the restoration of rosettes on normal trypsinized lymphocytes: application in certain hemopathies].","authors":"J Hainaut, J Dufer, E Jacob, R Duriez, A Laurens","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76247,"journal":{"name":"Nouvelle revue francaise d'hematologie; blood cells","volume":"18 1","pages":"257-9"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11543503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Coagulometer H21: automatic apparatus for the study of coagulation].","authors":"J Guimbretière, D Boudart","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76247,"journal":{"name":"Nouvelle revue francaise d'hematologie; blood cells","volume":"18 1","pages":"201-2"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12079272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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