Pub Date : 1977-12-01DOI: 10.1177/003591577707001205
R. C. Coombes, T. J. Powles, A. M. Neville
Cooper E H & Williams R E (1975) The Biology and Clinical Management of Bladder Cancer. Blackwell, Oxford Everitt B (1974) Cluster Analysis. Heinemann, London Franchimont P, Zangerle P F, Reuter A, Henrick J C & Molter F (1976) In: Cancer Related Antigens. Ed. P Franchimont North Holland, Amsterdam; pp 203-222 Gower J C (1971) Biometrics 27, 857-872 Jones J Hywel, Lennard-Jones J E, Morson B C, Chapman M, Sackin M J, Sneath P H A, Spicer C C & Card W I (1973) Quarterly Journal of Medicine 42, 715-732 Kramer I R H, Lucas R B, El-Labban N & Lister L (1970) British Journal of Cancer 24, 406, 426 Mantel N & Valand R S (1970) Biometrics 26, 547-558 Marriot F H C (1971) Biometrics 27, 501-514 Neville A M & Cooper E H (1976) Annals of Clinical Biochemistry 13, 283-305 Ritzmann S E & Daniels J C (1975) Serum Protein Abnormalities. Little Brown, Boston Solberg H E (1975) Scandinavian Journal of Clinical and Laboratory Investigation 35, 705-712 Tormey D C, Waalkes T P, Ahmann D, Gehrke C W, Zumwatt R W, Snyder J & Hansen H (1975) Cancer 35, 1095-1 100 Ward A H, Cooper E H, Turner R, Anderson J A & Neville A M (1977) British Journal of Cancer 35, 170 Winkel P (1974) Computers in Biomedical Research 7, 1 00-1 0 Wolf P L, Williams D & von der Muehll E (1973) Practical Clinical Enzymology and Biochemical Profiling. John Wiley, London
{"title":"Tumour Markers","authors":"R. C. Coombes, T. J. Powles, A. M. Neville","doi":"10.1177/003591577707001205","DOIUrl":"https://doi.org/10.1177/003591577707001205","url":null,"abstract":"Cooper E H & Williams R E (1975) The Biology and Clinical Management of Bladder Cancer. Blackwell, Oxford Everitt B (1974) Cluster Analysis. Heinemann, London Franchimont P, Zangerle P F, Reuter A, Henrick J C & Molter F (1976) In: Cancer Related Antigens. Ed. P Franchimont North Holland, Amsterdam; pp 203-222 Gower J C (1971) Biometrics 27, 857-872 Jones J Hywel, Lennard-Jones J E, Morson B C, Chapman M, Sackin M J, Sneath P H A, Spicer C C & Card W I (1973) Quarterly Journal of Medicine 42, 715-732 Kramer I R H, Lucas R B, El-Labban N & Lister L (1970) British Journal of Cancer 24, 406, 426 Mantel N & Valand R S (1970) Biometrics 26, 547-558 Marriot F H C (1971) Biometrics 27, 501-514 Neville A M & Cooper E H (1976) Annals of Clinical Biochemistry 13, 283-305 Ritzmann S E & Daniels J C (1975) Serum Protein Abnormalities. Little Brown, Boston Solberg H E (1975) Scandinavian Journal of Clinical and Laboratory Investigation 35, 705-712 Tormey D C, Waalkes T P, Ahmann D, Gehrke C W, Zumwatt R W, Snyder J & Hansen H (1975) Cancer 35, 1095-1 100 Ward A H, Cooper E H, Turner R, Anderson J A & Neville A M (1977) British Journal of Cancer 35, 170 Winkel P (1974) Computers in Biomedical Research 7, 1 00-1 0 Wolf P L, Williams D & von der Muehll E (1973) Practical Clinical Enzymology and Biochemical Profiling. John Wiley, London","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"843 - 845"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001205","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathology of neonatal respiratory distress.","authors":"J S Wigglesworth","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 12","pages":"861-3"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543528/pdf/procrsmed00088-0045.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11804682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of the mentally abnormal offender: integrated or parallel.","authors":"J Gunn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 12","pages":"877-80"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543554/pdf/procrsmed00088-0069.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11804685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1977-12-01DOI: 10.1177/003591577707001218
A. Rowland
Control of communicable disease is a function of the local authority. It is interesting to trace how this came about following the events of the Industrial Revolution. Towards the end of the eighteenth century and during the early part of the nineteenth, dramatic social changes occurred, resulting in the migration of large numbers of a predominantly country-dwelling population into the new towns and embryonic cities. With them they brought their rural modes of sanitation and environmental hygiene, which had been relatively adequate in the more sparsely populated countryside. There was no adequate administrative or legislative framework to contend with such a situation. Sir John Simon (1897) vividly describes the problems: land drains were doubling up ineffectively as foul sewers, domestic cesspools were often constructed in the basements of houses and there was no system of refuse disposal -'the householder stored his filth as he liked, or got rid of it as he could'. It was not surprising that, with overcrowding, malnutrition, and long hours of work superimposed on such circumstances, infections of all kinds became rampant (Brockington 1956). Cholera was introduced into the country in 1832, with disastrous results. The disease became widespread and mortality was immense. Although it cannot be adequately quantified because returns
控制传染病是地方当局的职责。在工业革命之后，追踪这种情况是如何发生的是很有趣的。在18世纪末和19世纪早期，发生了巨大的社会变化，导致大量主要居住在乡村的人口迁移到新的城镇和萌芽中的城市。他们带来了他们的农村卫生和环境卫生模式，这些在人口稀少的农村相对足够。没有适当的行政或立法框架来处理这种情况。约翰·西蒙爵士(Sir John Simon, 1897)生动地描述了这些问题:土地排水沟被低效地用作污水渠，家庭污水池通常建在房屋的地下室，而且没有垃圾处理系统——“户主喜欢怎么放就怎么放，或者怎么处理就怎么处理”。在这种情况下，由于过度拥挤、营养不良和长时间的工作，各种感染变得猖獗，这并不奇怪(Brockington 1956)。霍乱于1832年传入该国，造成了灾难性的后果。这种疾病蔓延开来，死亡率极高。虽然它不能被充分量化，因为回报
{"title":"Communicable Disease Control","authors":"A. Rowland","doi":"10.1177/003591577707001218","DOIUrl":"https://doi.org/10.1177/003591577707001218","url":null,"abstract":"Control of communicable disease is a function of the local authority. It is interesting to trace how this came about following the events of the Industrial Revolution. Towards the end of the eighteenth century and during the early part of the nineteenth, dramatic social changes occurred, resulting in the migration of large numbers of a predominantly country-dwelling population into the new towns and embryonic cities. With them they brought their rural modes of sanitation and environmental hygiene, which had been relatively adequate in the more sparsely populated countryside. There was no adequate administrative or legislative framework to contend with such a situation. Sir John Simon (1897) vividly describes the problems: land drains were doubling up ineffectively as foul sewers, domestic cesspools were often constructed in the basements of houses and there was no system of refuse disposal -'the householder stored his filth as he liked, or got rid of it as he could'. It was not surprising that, with overcrowding, malnutrition, and long hours of work superimposed on such circumstances, infections of all kinds became rampant (Brockington 1956). Cholera was introduced into the country in 1832, with disastrous results. The disease became widespread and mortality was immense. Although it cannot be adequately quantified because returns","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"885 - 889"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001218","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1977-12-01DOI: 10.1177/003591577707001213
J. Sachs
Since the introduction of COVID-19 vaccine, various adverse events have been reported including injection site pain, fatigue, headaches, and myocarditis. Cranial neuropathies and optic neuritis, have been also rarely reported, however, the significance of these autoimmune manifestations after the administration of COVID-19 vaccine remain controversial. In this report we present a case of myocarditis and bilateral optic neuritis that occurred in a young healthy male patient after the administration of first dose of mRNA-1273 vaccine (Moderna).
{"title":"Neuroimmunology","authors":"J. Sachs","doi":"10.1177/003591577707001213","DOIUrl":"https://doi.org/10.1177/003591577707001213","url":null,"abstract":"Since the introduction of COVID-19 vaccine, various adverse events have been reported including injection site pain, fatigue, headaches, and myocarditis. Cranial neuropathies and optic neuritis, have been also rarely reported, however, the significance of these autoimmune manifestations after the administration of COVID-19 vaccine remain controversial. In this report we present a case of myocarditis and bilateral optic neuritis that occurred in a young healthy male patient after the administration of first dose of mRNA-1273 vaccine (Moderna).","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"869 - 871"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1977-12-01DOI: 10.1177/003591577707001221
J. Byrne, A. Cochrane, D. Williams, R. Williams
REFERENCES Di Ferrante N, Leachman R D, Angelini P, Donnelly P V, Francis G & Almazan A (1975) Connective Tissue Research 3, 49 Pinnell S R, Krane S M, Kenzora J E & Glimcher M J (1972) New England Journal ofMedicine 286, 1013 Pope F M, Martin G R, Lichtenstein J R, Pentdnnen R, Gerson B, Rowe D W & McKusick V A (1975) Proceedings of the National Academy ofSciences of the USA 72, 1314 Pope F M, Martin G R & McKusick V A (1977) Journal of Medical Genetics 14, 200-204 Sussman M D, Lichtenstein J R, Nigra T P, Martin G R & McKusick V A (1974) Journal ofBone and Joint Surgery 56A, 1228-1231
{"title":"Cases","authors":"J. Byrne, A. Cochrane, D. Williams, R. Williams","doi":"10.1177/003591577707001221","DOIUrl":"https://doi.org/10.1177/003591577707001221","url":null,"abstract":"REFERENCES Di Ferrante N, Leachman R D, Angelini P, Donnelly P V, Francis G & Almazan A (1975) Connective Tissue Research 3, 49 Pinnell S R, Krane S M, Kenzora J E & Glimcher M J (1972) New England Journal ofMedicine 286, 1013 Pope F M, Martin G R, Lichtenstein J R, Pentdnnen R, Gerson B, Rowe D W & McKusick V A (1975) Proceedings of the National Academy ofSciences of the USA 72, 1314 Pope F M, Martin G R & McKusick V A (1977) Journal of Medical Genetics 14, 200-204 Sussman M D, Lichtenstein J R, Nigra T P, Martin G R & McKusick V A (1974) Journal ofBone and Joint Surgery 56A, 1228-1231","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"897 - 898"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001221","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1977-12-01DOI: 10.1177/003591577707001217
P. Bowden
a restriction of admissions and an increasing difficulty in discharging patients. The mental hospitals, which traditionally have accepted mentally disordered offenders, have been reduced in size and have also been influenced by contemporary liberal attitudes (Lancet 1976). The newer psychiatric units have selected patients with all the social, behavioural and diagnostic connotations of a 'good prognosis' (Little 1974). One judge has warned that the courts will turn again from psychiatry unless they are more favourably treated (Ormrod 1975), and the 'Annual Report of the work of the Prison Department' habitually belabours NHS psychiatry for abdicating its responsibility to care for mentally abnormal offenders. The work of Faulk & Trafford (1975) illustrates one aspect of this process; they identified four covert reasons for a custodial remand in which prison is used as a bail hostel for the homeless, a secure bail hostel for those who have broken bail, an acute alcoholic admission unit and
{"title":"Management of the Mentally Abnormal Offender","authors":"P. Bowden","doi":"10.1177/003591577707001217","DOIUrl":"https://doi.org/10.1177/003591577707001217","url":null,"abstract":"a restriction of admissions and an increasing difficulty in discharging patients. The mental hospitals, which traditionally have accepted mentally disordered offenders, have been reduced in size and have also been influenced by contemporary liberal attitudes (Lancet 1976). The newer psychiatric units have selected patients with all the social, behavioural and diagnostic connotations of a 'good prognosis' (Little 1974). One judge has warned that the courts will turn again from psychiatry unless they are more favourably treated (Ormrod 1975), and the 'Annual Report of the work of the Prison Department' habitually belabours NHS psychiatry for abdicating its responsibility to care for mentally abnormal offenders. The work of Faulk & Trafford (1975) illustrates one aspect of this process; they identified four covert reasons for a custodial remand in which prison is used as a bail hostel for the homeless, a secure bail hostel for those who have broken bail, an acute alcoholic admission unit and","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"881 - 884"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1977-12-01DOI: 10.1177/003591577707001214
Arman Fesharaki-Zadeh, Naomi Lowe, Amy F. T. Arnsten
the
的
{"title":"Neuroimmunology","authors":"Arman Fesharaki-Zadeh, Naomi Lowe, Amy F. T. Arnsten","doi":"10.1177/003591577707001214","DOIUrl":"https://doi.org/10.1177/003591577707001214","url":null,"abstract":"the","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"871 - 874"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001214","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1977-12-01DOI: 10.1177/003591577707001209
C. B. Wood
{"title":"Immune Deficiency","authors":"C. B. Wood","doi":"10.1177/003591577707001209","DOIUrl":"https://doi.org/10.1177/003591577707001209","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"858 - 860"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1977-12-01DOI: 10.1177/003591577707001204
E. H. Cooper, T. E. Kenny
The diagnosis of asymptomatic primary cancer still seems a distant prospect. Once the diagnosis of cancer has been established the clinician may require information that can be grouped under three headings: (1) Better indications of the probability of recurrence or metastases in patients treated by curative procedures. (2) Identification, as soon as possible, of recurrence or metastases. (3) To be able to follow the evolution of residual cancer remaining after treatment which cannot be detected clinically. It is hoped that this information, which may come in part from biochemical measurements, will enable the clinician to take appropriate action earlier than when routine clinical examination alone is used. This places heavy demands on biochemists, as firm base-line data will have to be established.
{"title":"Tumour Markers","authors":"E. H. Cooper, T. E. Kenny","doi":"10.1177/003591577707001204","DOIUrl":"https://doi.org/10.1177/003591577707001204","url":null,"abstract":"The diagnosis of asymptomatic primary cancer still seems a distant prospect. Once the diagnosis of cancer has been established the clinician may require information that can be grouped under three headings: (1) Better indications of the probability of recurrence or metastases in patients treated by curative procedures. (2) Identification, as soon as possible, of recurrence or metastases. (3) To be able to follow the evolution of residual cancer remaining after treatment which cannot be detected clinically. It is hoped that this information, which may come in part from biochemical measurements, will enable the clinician to take appropriate action earlier than when routine clinical examination alone is used. This places heavy demands on biochemists, as firm base-line data will have to be established.","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"70 1","pages":"840 - 843"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/003591577707001204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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