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A bacterial sensitivity test to determine the effectiveness of minocycline HCI (Minocin), erythromycin (Erythrocin) and ampicillin (Ampicin) on the predominant microorganisms present in a diseased periodontium. 测定米诺环素HCI(米诺霉素)、红霉素(红霉素)和氨苄西林(氨苄西林)对病变牙周组织中主要微生物的有效性的细菌敏感性试验。
B L Angeles, D R Book, K G Go, D J Lim, H G Uy

The purpose of this study was to determine the effectiveness of the three antimicrobials--Minocycline HCI, Erythromycin and Ampicillin based on the percentage reduction of bacteria present in subgingival microflora and in vitro assessment of antibiotic susceptibility of cultured strains of predominant microorganisms present in a diseased periodontium. Twelve volunteers 18 to 65 years of age, with moderate to severe periodontal disease, were randomly divided into Group A and Group B of 6 members each. Oral lavage procedure was performed to Group A and Group B received systemic administration of antibiotic for five days. Patients 1 & 2, 3 & 4 and 5 & 6 received minocycline HCI, Erythromycin and Ampicillin respectively. Microbiologic samples in the subgingival crevicular area in selected tooth exhibiting clinical periodontal breakdown were obtained from all the subjects prior to and after the oral lavage procedure and systemic drug administration. Streptococcus viridans is the most predominant aerobic microorganism obtained from 83% of samples. However no anaerobic microorganism has been isolated. Bacterial sensitivity testing showed 60% of samples with positive growth of microorganisms (S. viridans) were also equally sensitive to Minocycline HCI, Erythromycin and Ampicillin. Oral lavage proved to be ineffective in reducing the number of bacteria. However, systemic drug administration revealed that there was a reduction in bacterial count after taking such antibiotics for five days which is more favorable to Minocycline HCI.

本研究的目的是确定三种抗菌剂——米诺环素HCI、红霉素和氨苄西林的有效性,基于牙龈下菌群中细菌减少的百分比,以及对患病牙周组织中主要微生物培养菌株的抗生素敏感性的体外评估。12名年龄在18 ~ 65岁之间,患有中重度牙周病的志愿者,随机分为A组和B组,每组6人。A组患者行口腔灌洗,B组患者给予全身抗生素治疗5 d。患者1、2、3、4、5、6分别给予米诺环素HCI、红霉素、氨苄西林治疗。在所有受试者进行口腔灌洗和全身给药前后,分别采集有临床牙周破裂症状的牙齿龈下沟区微生物样本。青绿链球菌是83%样品中最主要的需氧微生物。但目前尚未分离出厌氧微生物。细菌敏感性测试显示,60%的微生物(绿脓杆菌)阳性生长的样品对米诺环素HCI、红霉素和氨苄西林同样敏感。口腔灌洗对减少细菌数量无效。然而,全身给药显示,在服用这种抗生素5天后,细菌计数减少,这对米诺环素HCI更有利。
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引用次数: 0
Do subgingival crown margins adversely affect the periodontium? 龈下牙冠缘对牙周组织有不良影响吗?
N V Vergel de Dios

With the increasing demand for cast restorations, the effect and influence of crown margins on the periodontium brought about many researches. These researches on crown margins were categorized by Gardner (1982) into three (3) broad categories namely: location, configuration and fit. Researchers on the influence of location of crown margins in the preparation of restorations, whether they be 1) supragingival 2) at the crest of the gingival margin or 3) subgingival, on the adjacent periodontal tissues had led to results which either supported the placement of cast restorations at one location level, that is, supragingivally, or those that support the view that the location of crown margins do not seem to significantly affect the periodontium.

随着铸型修复需求的增加,冠缘对牙周组织的影响引起了人们的广泛关注。Gardner(1982)将树冠边缘的研究分为三大类,即位置、结构和契合度。研究人员对修复体准备过程中冠缘位置的影响进行了研究,无论是1)龈上2)龈缘嵴还是3)龈下对邻近牙周组织的影响,结果要么支持将铸型修复体放置在一个位置水平,即龈上,要么支持冠缘位置似乎对牙周组织没有显著影响的观点。
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引用次数: 0
The control cast (an aid in detecting aberrations in F.P.D.). 控制模型(用于检测F.P.D.的畸变)。
E S Belen
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引用次数: 0
Histopathologic studies on wound healing caused by scalpel incision, cryosurgery and electrocautery on hamsters. 仓鼠手术刀切开、冷冻和电灼致创面愈合的组织病理学研究。
M M Mendoza, G R Tiemsen, G G Estioco, R T Tolentino, D M Bulatao, H G Uy

Scalpel incision, cryosurgery as demonstrated by the use of dry ice, and electrocautery have different effects both clinically and histologically. Twelve hamsters of equal weight were divided into four study groups to compare which of the three methods of incision initiates a faster healing capacity. Surgical incisions were made of equal depths and were observed after 2, 5, 10 and 12 days. Results showed a marked cellular infiltration in electrocautery as compared with the scalpel incision method and the dry ice incision.

手术刀切开、干冰冷冻手术和电灼在临床和组织学上都有不同的效果。将12只体重相等的仓鼠分为4个研究组,比较三种切口方法中哪一种能更快地启动愈合能力。手术切口深度等,分别于2、5、10、12天后观察。结果表明,与刀切法和干冰切法相比,电切法有明显的细胞浸润。
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引用次数: 0
Fountain of youth. 青春之泉。
R I Talag
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引用次数: 0
A comparative study: classical, Akinosi, and Gow-Gates techniques of mandibular nerve block. 经典、Akinosi和Gow-Gates下颌神经阻滞技术的比较研究。
E V Cruz, J B Quengua, I L Gutierrez, M A Abreu, H G Uy

This study was conducted to compare the effectiveness and the degree of patient acceptability of the three techniques of mandibular nerve block, namely the classical, the Akinosi and the Gow-Gates. Forty five patients with mandibular posterior tooth/teeth indicated for extraction were chosen and divided equally into three groups to represent the three techniques of mandibular nerve block. Following the administration of the local anesthetic, the patients were evaluated using the evaluation sheet prepared for the study. Tabulation and analysis of the collected data followed. Results show that the Gow-Gates technique was the most effective in inducing anesthesia while the Akinosi technique appeared to be the most acceptable among the patients.

本研究比较了经典、Akinosi和Gow-Gates三种下颌神经阻滞技术的有效性和患者的可接受程度。选择45例下颌后牙/牙需要拔除的患者,平均分为三组,分别代表下颌神经阻滞的三种技术。在给药后,使用为研究准备的评估表对患者进行评估。随后对收集到的数据进行制表和分析。结果表明,高-盖茨麻醉诱导效果最好,而Akinosi麻醉诱导效果最好。
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引用次数: 0
Tooth recontouring/reshaping a must in the preparation for removable partial denture. 在可摘局部义齿的准备工作中,牙齿的整形是必须的。
A U Ang
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引用次数: 0
Histological and immunochemical studies of oral leukoplakia: phenotype and distribution of immunocompetent cells. 口腔白斑的组织学和免疫化学研究:免疫活性细胞的表型和分布。
Pub Date : 1994-04-20 DOI: 10.2330/JORALBIOSCI1965.36.87
G. G. Bondad-Palmario
The Phenotype and distribution of immunocompetent cells in oral leukoplakia with different levels of dysplasia were analyzed. Cells were identified in two compartments of the oral mucosa, the epithelium and subepithelial connective tissue. One hundred cases of neutral-buffered formalin-fixed paraffin embedded biopsy materials including 10 cases of acetone-fixed frozen tissue sections were studied immunohistochemically. In the main lymphoid population of each groups, the T lymphocytes predominated over the B lymphocytes. The lymphoid cells were present either as diffuse aggregates or organized in follicular patterns with or without germinal center-like structures. When present, B lymphocytes were seen to constitute the above mentioned structures. T lymphocytes made up the paracortical areas. A decrease in CD4/CD8 ratio was observed in cases with severe dysplasia. Specimens classified as mild to severe dysplasia presented a significant increase in the number of CD1a (+) dendritic Langerhans cells when compared with those of epithelial hyperplasia. A significant increase in macrophage count was also obtained in the subephitelial connective tissue of all dysplastic cases. A significant increase of CD57 (+) natural killer/killer cells in the subephitelial connective tissue and HLA-DR expression by the keratinocytes was observed in cases with severe dysplasia. Correlation and analysis of the results revealed an immunocellular reaction that varied according to the degree of dysplasia in oral leukoplakia. Immunologic events, i.e. decreased CD4/CD8 ratio, increased density of natural killer/killer cells and HLA-DR expression by keratinocytes, occurring simultaneously in severe dysplasia are speculated to be indicative of early malignant transformation.
分析不同程度不典型增生口腔白斑中免疫活性细胞的表型和分布。在口腔黏膜的上皮和上皮下结缔组织两个区室中发现了细胞。对100例中性缓冲福尔马林固定石蜡包埋活检材料进行免疫组织化学研究,其中10例为丙酮固定冷冻组织切片。在各组的主要淋巴细胞群中,T淋巴细胞多于B淋巴细胞。淋巴样细胞呈弥漫性聚集体或滤泡状组织,有或没有生发中心样结构。当存在时,可以看到B淋巴细胞构成上述结构。T淋巴细胞组成皮层旁区。严重不典型增生患者CD4/CD8比值降低。与上皮增生的标本相比,轻度至重度发育不良的标本CD1a(+)树突状朗格汉斯细胞的数量显著增加。在所有发育不良病例的上皮下结缔组织中,巨噬细胞计数也显著增加。严重发育不良患者上皮下结缔组织中CD57(+)自然杀伤细胞/杀伤细胞显著增加,角化细胞中HLA-DR表达显著增加。结果的相关性和分析显示,免疫细胞反应根据口腔白斑发育不良的程度而变化。免疫事件,即CD4/CD8比值降低,自然杀伤细胞/杀伤细胞密度增加,角质形成细胞HLA-DR表达增加,同时发生在严重的不典型增生中,推测是早期恶性转化的指示。
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引用次数: 16
Applicability and future scope of lasers in dental practice. 激光在牙科实践中的适用性和未来范围。
T Morioka
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引用次数: 0
Personal computers in dentistry. 牙科中的个人电脑。
F Co
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引用次数: 0
期刊
The Journal of the Philippine Dental Association
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