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A five-year evaluation of implants placed in extraction sockets. 在拔牙槽内放置种植体的五年评估。
E S Tsai, C C Crohin, H P Weber

The aim of this study is to examine extraction socket implant longevity and peri-implant conditions longitudinally and to compare the outcome with implants placed in intact alveolar bone sites (nonextraction sites) after a time period in function of five years or more. We hypothesize that implants placed into fresh extraction sockets have a long-term rate of success similar to that of conventionally placed implants. Eleven extraction socket implants in eight patients with a follow-up of at least five years were included in this report. The implants were loaded with either single-tooth replacements or three-to-four-unit fixed partial dentures after healing times of four to six months. Intraoral radiographs of the 11 implants were obtained immediately after surgery and upon recall five to seven years after surgery. In addition, the following clinical parameters were evaluated at each implant site five to seven years postsurgery: plaque indices (PT), bleeding indices (BI), probing depths, attachment level (AL), and distance from implant shoulder to mucosal margin (DIM). As a control, 11 implants from a previous long-term study of nonsubmerged implants placed into intact alveolar bone sites by the same clinician were matched by implant location, sex, and age. Initial and long-term follow-up radiographs of the experimental and control groups were scanned into a computer. A computer program designed for radiographic implant analysis was utilized to examine the changes in radiographic bone levels over time in the two groups. After a period of five to seven years, the mean bone loss for the immediate implant group was 0.167 mm, while that of the control group was 0.460 mm. An unpaired t-test resulted in a P value = 0.0563, indicating that the mean change in bone levels between the two groups is not statistically significant. In addition, clinical evaluation parameters (PI, BI, AL, DIM) revealed no significant difference between the two groups. Therefore, it can be stated that in this study the long-term success rate for extraction socket implants is similar to that of conventionally placed implants.

本研究的目的是纵向检查拔牙槽种植体的寿命和种植体周围的情况,并将其与放置在完整牙槽骨部位(非拔牙部位)的种植体在功能5年或更长时间后的结果进行比较。我们假设种植体放置在新鲜的拔牙槽中具有与传统放置种植体相似的长期成功率。我们对8例患者进行了随访,随访时间至少为5年。在4到6个月的愈合时间后,种植体被装入单齿替代物或3到4个单元的固定部分假牙。11个种植体的口腔内x线片在手术后立即获得,在手术后5至7年回忆时获得。此外,在术后5 - 7年评估每个种植体部位的以下临床参数:斑块指数(PT)、出血指数(BI)、探查深度、附着水平(AL)和种植体肩部到粘膜边缘的距离(DIM)。作为对照,来自先前一项长期研究的11个种植体,由同一临床医生将非浸入式种植体放置在完整的牙槽骨部位,并根据种植体位置、性别和年龄进行匹配。实验组和对照组的初始和长期随访x光片被扫描到计算机中。一个为植入物放射学分析设计的计算机程序被用来检查两组放射学骨水平随时间的变化。5 ~ 7年后,即刻种植组的平均骨丢失为0.167 mm,而对照组的平均骨丢失为0.460 mm。非配对t检验P值= 0.0563,说明两组骨水平的平均变化无统计学意义。临床评价指标(PI、BI、AL、DIM)两组间差异无统计学意义。因此,可以认为在本研究中,拔牙槽种植体的长期成功率与常规种植体相似。
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引用次数: 0
The use of triclosan in supportive treatment of gingivitis and periodontitis. 三氯生在牙龈炎和牙周炎支持治疗中的应用。
T Q Hoang
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引用次数: 0
The treatment of a localized osseous sequestrum with porous bone mineral in combination with a collagen membrane and resorbable bone pins. 用多孔骨矿物质结合胶原膜和可吸收骨钉治疗局部骨残骨。
T Ilgenli, T Günbay, H Baylas

The ultimate goal of periodontal therapy should not be limited to the establishment and maintenance of periodontal health. The potential regeneration of the hard and soft periodontal tissues lost due to disease also should be considered. This case presentation evaluated a new surgical technique for the treatment of a variety of localized bone defects, utilizing porous bone mineral in combination with collagen membrane and resorbable bone pins.

牙周治疗的最终目标不应局限于建立和维持牙周健康。由于疾病造成的牙周软硬组织的再生也应考虑在内。本病例报告评估了一种治疗各种局部骨缺损的新手术技术,利用多孔骨矿物质结合胶原膜和可吸收骨钉。
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引用次数: 0
Do mutations in the basement membrane zone affect the human periodontium? Review with special reference to epidermolysis bullosa. 基底膜带的突变会影响人的牙周组织吗?回顾大疱性表皮松解症。
C B Wiebe, H S Larjava

Epidermolysis bullosa (EB) is a group of diseases characterized by the development of blisters or erosions following minor trauma to the skin. Oral findings that have been associated with EB include keratin-filled cysts; blistering of the mucosa, tongue, and lips; perioral carcinomas; ankyloglossia; lingual papilla atrophy; caries; enamel hypoplasia; rapid attrition of the teeth; and obliteration of the oral vestibule. Defects at the basal cell/basement membrane/connective tissue levels correspond to the mutations in basal cell keratins, hemidesmosome components, and type VII collagen, respectively. In a number of types of EB, structural defects in the skin have been shown and genetic mutations determined. Although there are no publications documenting the prevalence of periodontal diseases in patients with epidermolysis bullosa, it is likely that some molecular defects in the basement membrane zone could increase the susceptibility of a patient to periodontal disease, as this has been noted in the related disorder of Weary-Kindler syndrome. Early-onset periodontal disease can be expected to develop in some types of EB patients, even in the absence of common periodontal pathogens, because of a reduced resistance at the junctional epithelial complex.

大疱性表皮松解症(EB)是一组以皮肤轻微创伤后出现水疱或糜烂为特征的疾病。与EB相关的口腔表现包括角蛋白填充囊肿;起泡粘膜、舌头和嘴唇起泡;口周的癌;舌系带短缩;舌乳头萎缩;龋齿;牙釉质发育不全;牙齿迅速磨损;以及口腔前庭的消失。基底细胞/基底膜/结缔组织水平的缺陷分别对应于基底细胞角蛋白、半脂体成分和VII型胶原蛋白的突变。在许多类型的EB中,已经显示出皮肤的结构缺陷和基因突变。虽然没有文献记载大疱性表皮松解症患者牙周病的患病率,但基底膜区的一些分子缺陷可能会增加患者对牙周病的易感性,正如在相关疾病疲劳-金德勒综合征中所注意到的那样。早发性牙周病可能发生在某些类型的EB患者中,甚至在没有常见牙周病原体的情况下,因为交界上皮复合体的抵抗力降低。
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引用次数: 0
Implant surface alterations from a nonmetallic ultrasonic tip. 非金属超声针尖对植入物表面的改变。
G M Bailey, J S Gardner, M H Day, B J Kovanda

This study evaluates surface alterations produced on various implant surfaces by an ultrasonic scaler fitted with a nonmetallic tip. Commercially pure titanium and titanium alloy abutments, plasma-coated implants, and hydroxyapatite-coated implants were contacted with the nonmetallic tip for 10 seconds and then evaluated for surface changes by SEM examination. The commercially pure titanium and titanium alloy surfaces showed negligible alterations from the control, thus indicating possible clinical use as a maintenance device. More severe changes were evidenced with the plasma- and hydroxyapatite-coated surfaces.

本研究评估了用非金属尖端的超声波秤对不同种植体表面产生的表面变化。将商用纯钛和钛合金基台、等离子涂层种植体和羟基磷灰石涂层种植体与非金属尖端接触10秒,然后通过扫描电镜检查评估表面变化。商业纯钛和钛合金表面显示出与对照组相比可以忽略不计的变化,因此表明可能在临床使用作为维护装置。等离子体和羟基磷灰石涂层的表面表现出更严重的变化。
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引用次数: 0
Comparison of postoperative bupivacaine with lidocaine on pain and analgesic use following periodontal surgery. 布比卡因与利多卡因对牙周手术后疼痛及镇痛作用的比较。
M J Kaurich, J Otomo-Corgel, R J Nagy

The purpose of this study was to compare postoperative administration of bupivacaine, a long-acting local anesthetic, with lidocaine, a short-acting local anesthetic, on pain perception and analgesic use following periodontal surgery. Ten male subjects were selected on the basis of having similar bilateral mandibular quadrants with moderate to severe periodontal disease requiring osseous surgery. The study was a matched-pair, double-blind design. Carpules of 2% xylocaine with 1:100,000 epinephrine and 0.5% bupivacaine with 1:200,000 epinephrine were wrapped in opaque tape and placed in separate coded envelopes. At the time of suturing, the quadrant was injected with one Carpule from one envelope. The Carpules from the second envelope were saved for the second surgery, which took place approximately one month later. Subjects were given standardized postoperative instructions and prescriptions for Peridex and Tylenol #3. They were told not to take the analgesic unless pain or discomfort occurred. They were given a self-administered questionnaire and asked to assess pain and/or discomfort 2, 4, 6, 8, 10, and 12 hours after the procedure, the amount of analgesic taken, and time when complete sensation returned. Results showed that the quadrants which received lidocaine maintained postoperative anesthesia an average of 2.47 hours while the Marcaine quadrants had a significantly longer duration of 5.62 hours. A large intra- and intersubject variability was noted in the amount of analgesic taken. The lidocaine group reported an average of 3.70 tablets versus a significantly smaller amount for the bupivacaine group of 1.60 tablets. Throughout all time intervals, the bupivacaine group reported significantly less pain than the lidocaine group. When used at the end of a mandibular periodontal surgical procedure, bupivacaine provides a significantly greater duration of anesthesia, decreased postoperative pain, and a reduction of anesthesia, decreased postoperative pain, and a reduction in the amount of analgesics taken.

本研究的目的是比较布比卡因(一种长效局麻药)和利多卡因(一种短效局麻药)对牙周手术后疼痛感知和镇痛使用的影响。选取双侧下颌象限相似且患有中度至重度牙周病且需要骨外科手术的男性受试者10名。该研究采用配对双盲设计。2%木卡因和0.5%布比卡因分别加1:10万肾上腺素和1:20万肾上腺素的药瓶用不透明胶带包裹,放在单独的编码信封中。在缝合时,从一个包膜中注射一枚卡普勒。第二次手术大约在一个月后进行。受试者接受标准化的术后指导和处方,使用Peridex和泰诺#3。他们被告知,除非出现疼痛或不适,否则不要服用止痛药。给他们一份自我管理的问卷,并要求他们在手术后2、4、6、8、10和12小时评估疼痛和/或不适,止痛药的用量,以及完全感觉恢复的时间。结果显示,利多卡因组术后麻醉维持时间平均为2.47小时,而可卡因组术后麻醉维持时间明显延长,为5.62小时。在服用镇痛药的量上,受试者内部和受试者之间存在很大的差异。利多卡因组平均服用3.70片,而布比卡因组平均服用1.60片。在所有时间间隔内,布比卡因组报告的疼痛明显小于利多卡因组。当在下颌牙周外科手术结束时使用布比卡因时,麻醉时间明显延长,术后疼痛减轻,麻醉减轻,术后疼痛减轻,镇痛药用量减少。
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引用次数: 0
Clinical trial designs for testing of products for dentine hypersensitivity--a review. 牙本质过敏产品试验的临床试验设计综述。
D G Gillam

Dentine hypersensitivity (DH) is a perplexing clinical entity. There is no doubt that patients self-report discomfort arising from various stimuli, but the highly subjective nature of the condition makes it extremely difficult to evaluate DH objectively. This is particularly true when evaluating the efficacy of desensitizing agents in the clinical trial setting. This paper attempts to provide an overview on clinical trial management to evaluate both in-office and over-the-counter (OTC) desensitizing agents. The importance of correct clinical trial design (type, allocation, blinding) with emphasis on patient selection, sample size, statistical power, duration, choice of positive/negative controls, treatment outcomes, and data collection, will be discussed.

牙本质过敏症(DH)是一个令人困惑的临床问题。毫无疑问,患者自我报告各种刺激引起的不适,但这种情况的高度主观性使得客观评估DH极其困难。在临床试验中评估脱敏剂的疗效时尤其如此。本文试图提供临床试验管理的概述,以评估在办公室和非处方(OTC)脱敏剂。将讨论正确临床试验设计(类型、分配、盲法)的重要性,重点是患者选择、样本量、统计效力、持续时间、阳性/阴性对照的选择、治疗结果和数据收集。
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引用次数: 0
Drug-induced gingival overgrowth after phenytoin and nifedipine therapy. A case report. 苯妥英和硝苯地平治疗后药物性牙龈过度生长。一份病例报告。
R Slezák
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引用次数: 0
The effectiveness of desensitizing agents for the treatment of cervical dentine sensitivity (CDS)--a review. 脱敏剂治疗牙本质敏感性(CDS)的有效性综述。
T Y Ling, D G Gillam

The treatment of dentine sensitivity or cervical dentine sensitivity (CDS) has been in the form of dentifrices, mouth rinses, sealants, and other therapeutic techniques. Claims of efficacy of the "so-called" active ingredients of these desensitizing agents have been made on the basis of the proposed mode of action generally extrapolated from in vitro or animal studies. Evidence from published, well-controlled clinical studies, however, generally has failed to substantiate such claims, although there has been a reported significant reduction in discomfort by subjects participating in these studies. Currently, the most accepted mechanism of intradental nerve activity associated with dentine sensitivity appears to be hydrodynamic in nature, although other mechanisms cannot be eliminated. The concept of tubule occlusion as a method of dentine desensitization is a logical conclusion from the hydrodynamic hypothesis. This paper reviews the present position with regard to the treatment of dentine sensitivity by various desensitizing agents and evaluates their claims of efficacy in the context of available scientific evidence.

牙本质敏感或颈牙本质敏感(CDS)的治疗一直以牙膏、漱口水、密封剂和其他治疗技术的形式存在。这些脱敏剂的“所谓”活性成分的功效声称是基于通常从体外或动物研究中推断出来的拟议的作用模式而做出的。然而,来自已发表的、控制良好的临床研究的证据通常无法证实这种说法,尽管有报道称,参加这些研究的受试者的不适程度显著减少。目前,最被接受的与牙本质敏感性相关的牙本质内神经活动的机制似乎是水动力学的,尽管其他机制不能消除。小管闭塞作为牙本质脱敏方法的概念是水动力假说的逻辑结论。本文回顾了目前有关治疗牙本质敏感性的各种脱敏剂的位置,并在现有科学证据的背景下评估了它们的功效主张。
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引用次数: 0
Frequency of furcation closure with regenerative periodontal therapy. 再生牙周治疗中分叉闭合的频率。
G H Evans, R A Yukna, D L Gardiner, K M Cambre

A review of the literature was performed related to the frequency of closure of Grade II furcations with various regenerative therapies such as bone replacement grafts (BRG), coronally positioned flaps (CPF), guided tissue regeneration barriers (GTR), or open flap debridement (OFD). Fifty papers involving 1,016 furcations were evaluated. Complete furcation closure was reported only 20% of the time. Clinical change from Grade II to Grade I (partial furcation fill) was found in an additional 33% of the cases. Therefore, general improvement in clinical furcation status has been reported only about 50% of the time. The most effective furcation regenerative therapy was the combination of GTR plus BRG (91% overall positive). Similar overall positive results (88%) were achieved with nondemineralized allogeneic freeze-dried bone plus tetracycline without a barrier. The least effective therapy for regeneration in furcations was OFD (2% complete furcation closures and 13% partial furcation closures). If complete furcation closure is a primary goal of regenerative therapy, that goal would not appear to be commonly met.

我们回顾了与各种再生疗法如骨置换移植物(BRG)、冠状定位皮瓣(CPF)、引导组织再生屏障(GTR)或开放皮瓣清创(OFD)关闭II级功能频率相关的文献。评估了涉及1,016个功能的50篇论文。完全关闭分叉的几率仅为20%。另外33%的病例发现临床变化从II级到I级(部分分叉填充)。因此,只有大约50%的时间报告了临床功能状态的普遍改善。最有效的分叉再生治疗是GTR + BRG联合治疗(91%总阳性)。非脱矿的同种异体冻干骨加无屏障四环素获得了类似的总体阳性结果(88%)。功能再生最无效的治疗方法是OFD(2%完全功能关闭和13%部分功能关闭)。如果完全功能关闭是再生治疗的主要目标,那么这个目标似乎不会普遍实现。
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引用次数: 0
期刊
The Journal of the Western Society of Periodontology/Periodontal abstracts
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