首页 > 最新文献

American Journal of Health, Medicine and Nursing Practice最新文献

英文 中文
Prevalence of Cervical Spondylotic Myelopathy Among Patients with Cervical Spondylosis 颈椎病患者中脊髓型颈椎病的患病率
Pub Date : 2023-10-13 DOI: 10.47672/ajhmn.1615
Rafia Shahzadi, Raheela Kousar, Muhammad Zain, Farooq Islam, Asim Raza
Purpose: To calculate the prevalence of cervical spondylotic myelopathy among patients with cervical spondylosis. Methodology: The cross-sectional study was conducted in district Gujrat and Gujranwala on patients with cervical spondylosis in order to evaluate the prevalence of cervical spondylotic myelopathy among them. Data (n=186) was collected through non-probability convenient sampling using a Japanese orthopedic association cervical myelopathy evaluation questionnaire with the reliability of 0.89–0.96 by making a personal visit to different clinics and hospitals in Gujrat. Findings: The prevalence of cervical spondylotic myelopathy in patients with cervical spondylosis was 62.37%. The prevalence among different age group varied with the highest prevalence among age group 61-65 years old (30.2%). Moreover, it was higher in males than in females (52.6% vs 47.4%). The study also observed significant association between age and prevalence of cervical spondylotic myelopathy as they have p-value (0.000). This study concluded that the prevalence of cervical spondylotic myelopathy is high in cervical spondylosis patients. It appears that advance age may be the factor responsible for cervical spondylotic myelopathy, as cervical spondylosis is more prevalent in older individuals. Recommendations: There is a need to investigate the impact of lifestyle factors such as physical activity and posture on the frequency and severity of cervical spondylotic myelopathy. Both clinical assessment and imaging techniques should be considered to accurately diagnose and evaluate the severity of CSM. To explore potential correlation between the duration and progression of cervical spondylosis and development of CSM further studies should be conducted.
目的:计算颈椎病患者脊髓型颈椎病的患病率。 方法:在古吉拉特和古兰瓦拉地区对颈椎病患者进行横断面研究,评估其中脊髓型颈椎病的患病率。数据(n=186)采用非概率方便抽样,采用日本骨科协会颈椎病评估问卷(信度为0.89-0.96),亲自走访古吉拉特邦不同的诊所和医院。 结果:颈椎病患者中脊髓型颈椎病患病率为62.37%。不同年龄组患病率差异较大,61 ~ 65岁年龄组患病率最高(30.2%)。此外,男性高于女性(52.6%比47.4%)。该研究还观察到年龄与脊髓型颈椎病患病率之间的显著相关性,它们具有p值(0.000)。本研究认为,脊髓型颈椎病的患病率在颈椎病患者中较高。高龄可能是导致脊髓型颈椎病的因素,因为颈椎病在老年人中更为普遍。 建议:有必要调查生活方式因素如体力活动和姿势对脊髓型颈椎病发病频率和严重程度的影响。要准确诊断和评价脊髓型颈椎病的严重程度,应综合考虑临床评估和影像学技术。为探讨颈椎病病程、进展与脊髓型颈椎病发展之间的潜在关系,还需进一步研究。
{"title":"Prevalence of Cervical Spondylotic Myelopathy Among Patients with Cervical Spondylosis","authors":"Rafia Shahzadi, Raheela Kousar, Muhammad Zain, Farooq Islam, Asim Raza","doi":"10.47672/ajhmn.1615","DOIUrl":"https://doi.org/10.47672/ajhmn.1615","url":null,"abstract":"Purpose: To calculate the prevalence of cervical spondylotic myelopathy among patients with cervical spondylosis.
 Methodology: The cross-sectional study was conducted in district Gujrat and Gujranwala on patients with cervical spondylosis in order to evaluate the prevalence of cervical spondylotic myelopathy among them. Data (n=186) was collected through non-probability convenient sampling using a Japanese orthopedic association cervical myelopathy evaluation questionnaire with the reliability of 0.89–0.96 by making a personal visit to different clinics and hospitals in Gujrat.
 Findings: The prevalence of cervical spondylotic myelopathy in patients with cervical spondylosis was 62.37%. The prevalence among different age group varied with the highest prevalence among age group 61-65 years old (30.2%). Moreover, it was higher in males than in females (52.6% vs 47.4%). The study also observed significant association between age and prevalence of cervical spondylotic myelopathy as they have p-value (0.000). This study concluded that the prevalence of cervical spondylotic myelopathy is high in cervical spondylosis patients. It appears that advance age may be the factor responsible for cervical spondylotic myelopathy, as cervical spondylosis is more prevalent in older individuals.
 Recommendations: There is a need to investigate the impact of lifestyle factors such as physical activity and posture on the frequency and severity of cervical spondylotic myelopathy. Both clinical assessment and imaging techniques should be considered to accurately diagnose and evaluate the severity of CSM. To explore potential correlation between the duration and progression of cervical spondylosis and development of CSM further studies should be conducted.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135854598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Lumbosacral Angle Variation Among Middle Adults with Chronic Low Back Pain 中年成人慢性腰痛患者腰骶角变化的评估
Pub Date : 2023-10-11 DOI: 10.47672/ajhmn.1614
Muhammad Zain, Raheela Kousar, Rafia Shahzadi, Farooq Islam, Asim Raza
Purpose: To Assess Assessment of lumbosacral angle variation in middle adults with chronic low back pain. Methodology: A cross sectional study was conducted with sample size of 267 individuals from middle adults of Sikandar Medical complex Gujranwala, District Headquarter hospital Gujranwala, Gujranwala medical complex, Gujranwala. The population was Middle Adults (45-65) of both genders. Angle was measured by Measuring scale and Protractor using X-ray of lateral view of lumbosacral spine. Obtained data were analyzed using statistical package of social sciences (SPSS). Findings: The data has been obtained from 267 chronic low back pain patient in which 143 were male and 124 were female. Data was collected using lateral radiograph. The results show significant relation between chronic low back pain and lumbosacral angle with p-value ˂0.5. The result further shows that 32 male and 27 female were hypo lordotic while 89 male and 92 female were hyper lordotic. Conclusion: The study concluded that lumbosacral angle increases with chronic low back pain among middle adults. The study also concludes that age, gender also associated with lumbosacral angle variation. Recommendations: Future study needs a through physical examination. This study focuses on radiographs only but future study needs to focus on MRI and CT scan also for better understanding of pain causes. Awareness program should be conducted on causes, prevention, complication and treatment of chronic low back pain among middle adults
目的:探讨中年成人慢性腰背痛患者腰骶角变化的评估方法。 方法:采用横断面研究方法,选取古吉兰瓦拉西坎达医疗中心、古吉兰瓦拉地区总部医院、古吉兰瓦拉医疗中心的267名中年成年人为样本。人群为中年成年人(45-65岁),男女皆有。采用腰骶棘侧位x线片,用体尺和量角器测量角度。获得的数据使用社会科学统计软件包(SPSS)进行分析。 研究结果:研究数据来自267例慢性腰痛患者,其中143例为男性,124例为女性。通过侧位x线片收集数据。结果表明,腰骶角与慢性腰痛的相关性与p值的值小于0.5有显著关系。结果进一步表明,男性32例,女性27例,男性89例,女性92例。结论:中年人腰骶角随慢性腰痛增加。该研究还得出结论,年龄、性别也与腰骶角的变化有关。建议:今后的学习需要进行全面的身体检查。本研究仅关注x线片,但未来的研究还需要关注MRI和CT扫描,以更好地了解疼痛的原因。对中年人慢性腰痛的病因、预防、并发症及治疗进行认识
{"title":"Assessment of Lumbosacral Angle Variation Among Middle Adults with Chronic Low Back Pain","authors":"Muhammad Zain, Raheela Kousar, Rafia Shahzadi, Farooq Islam, Asim Raza","doi":"10.47672/ajhmn.1614","DOIUrl":"https://doi.org/10.47672/ajhmn.1614","url":null,"abstract":"Purpose: To Assess Assessment of lumbosacral angle variation in middle adults with chronic low back pain.
 Methodology: A cross sectional study was conducted with sample size of 267 individuals from middle adults of Sikandar Medical complex Gujranwala, District Headquarter hospital Gujranwala, Gujranwala medical complex, Gujranwala. The population was Middle Adults (45-65) of both genders. Angle was measured by Measuring scale and Protractor using X-ray of lateral view of lumbosacral spine. Obtained data were analyzed using statistical package of social sciences (SPSS).
 Findings: The data has been obtained from 267 chronic low back pain patient in which 143 were male and 124 were female. Data was collected using lateral radiograph. The results show significant relation between chronic low back pain and lumbosacral angle with p-value ˂0.5. The result further shows that 32 male and 27 female were hypo lordotic while 89 male and 92 female were hyper lordotic.
 Conclusion: The study concluded that lumbosacral angle increases with chronic low back pain among middle adults. The study also concludes that age, gender also associated with lumbosacral angle variation.
 Recommendations: Future study needs a through physical examination. This study focuses on radiographs only but future study needs to focus on MRI and CT scan also for better understanding of pain causes. Awareness program should be conducted on causes, prevention, complication and treatment of chronic low back pain among middle adults","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136213183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Orbital Rhabdomyosarcoma with Intracranial Extension in an Adult: Diagnostic and Management Challenges 1例成人眼眶横纹肌肉瘤伴颅内扩展:诊断和治疗挑战
Pub Date : 2023-10-09 DOI: 10.47672/ajhmn.1612
Oduware Gloria Ugboaku (MBBS), Edema, Temituoyo Folusho (MD), Ikhile Emmanuel Aimebelomo, Eghobamien Mine Oghomwenoyemwen (MBBS), Edema Omolabake Tolutope
Purpose: To report a rare case of orbital rhabdomyosarcoma with intracranial extension in an adult and the challenges in managing this case. Methodology: Research design was through a case report, while data was collected through observation, analysis of medical records and individual interviews. Interpretation of data was through the qualitative method of data analysis. Findings: A 34-year-old female meat seller was referred to our center with a rapidly progressive protrusion of the right eye of one month duration. She had a previous history of a penetrating injury to the right globe with bone fragment retention. She had had evisceration. Two weeks post-surgery, she noticed pain and a progressively worsening swelling around the right orbit. In our center, an initial diagnosis of orbital cellulitis post-evisceration was entertained. Orbito-cranial CT scan and MRI done showed a large homogenous irregular soft tissue mass occupying the right orbital cavity with extension to the right lateral rectus, lacrimal gland, cavernous sinus, optic nerve and brain parenchyma; findings were suggestive of orbital rhabdomyosarcoma with intracranial extension. The patient was discharged against medical advice. She re-presented 7 weeks later with a much larger mass which had multiple friable bleeding sites. With much assurance by the oncologists, she had several blood transfusions and 6 courses of chemotherapy. Tumour regression was very impressive. Incisional biopsy and histology confirmed rhabdomyosarcoma with chemotherapeutic changes. The patient was stable and so referred to another tertiary center for External Beam Radiation Therapy (EBRT), but this was delayed due to financial constraints. Two months from her referral for EBRT, colleagues reported she died of intractable seizures Recommendations: This study is based on suggestions that therapeutic success for rhabdomyosarcoma is better in children with survival rates reaching 75% unlike in adults where prognosis is poor.1 In this report, remission was observed soon after commencement of treatment. Therefore, it is recommended that early diagnosis be done to improve outcomes. Secondly, combination drugs should be used in all rhabdomyosarcoma cases. Lastly, government policies geared towards universal health coverage should be made and implemented.
目的:报告一例罕见的成人眼眶横纹肌肉瘤伴颅内延伸及治疗的挑战。 研究方法:采用病例报告的方式进行研究设计,通过观察、病历分析和个人访谈的方式收集数据。数据的解释是通过数据分析的定性方法。 结果:一名34岁女性卖肉者因右眼快速进行性突出持续一个月而被转介到我们中心。她曾有右眼球穿透伤伴骨碎片潴留的病史。她被掏空了内脏。手术后两周,她感到疼痛,右眼眶周围肿胀逐渐加重。在我们的中心,初步诊断眼眶蜂窝织炎后内脏接受。眶颅CT及MRI示:右侧眶腔内有一大块均匀不规则软组织肿块,累及右外侧直肌、泪腺、海绵窦、视神经及脑实质;结果提示眼眶横纹肌肉瘤伴颅内延伸。病人不顾医嘱出院了。7周后,她再次出现了一个更大的肿块,并有多个易碎的出血部位。在肿瘤学家的保证下,她输了几次血,做了6个疗程的化疗。肿瘤消退非常明显。切口活检和组织学证实横纹肌肉瘤伴化疗改变。患者病情稳定,因此转到另一个三级中心进行外束放射治疗(EBRT),但由于资金限制而推迟。在她转诊EBRT两个月后,同事报告她死于顽固性癫痫 建议:该研究基于以下建议:儿童横纹肌肉瘤的治疗成功率更高,存活率可达75%,而成人则预后较差在本报告中,在开始治疗后不久就观察到缓解。因此,建议早期诊断以改善预后。其次,所有横纹肌肉瘤病例均应联合用药。最后,应制定和执行面向全民健康覆盖的政府政策。
{"title":"A Case of Orbital Rhabdomyosarcoma with Intracranial Extension in an Adult: Diagnostic and Management Challenges","authors":"Oduware Gloria Ugboaku (MBBS), Edema, Temituoyo Folusho (MD), Ikhile Emmanuel Aimebelomo, Eghobamien Mine Oghomwenoyemwen (MBBS), Edema Omolabake Tolutope","doi":"10.47672/ajhmn.1612","DOIUrl":"https://doi.org/10.47672/ajhmn.1612","url":null,"abstract":"Purpose: To report a rare case of orbital rhabdomyosarcoma with intracranial extension in an adult and the challenges in managing this case.
 Methodology: Research design was through a case report, while data was collected through observation, analysis of medical records and individual interviews. Interpretation of data was through the qualitative method of data analysis.
 Findings: A 34-year-old female meat seller was referred to our center with a rapidly progressive protrusion of the right eye of one month duration. She had a previous history of a penetrating injury to the right globe with bone fragment retention. She had had evisceration. Two weeks post-surgery, she noticed pain and a progressively worsening swelling around the right orbit. In our center, an initial diagnosis of orbital cellulitis post-evisceration was entertained. Orbito-cranial CT scan and MRI done showed a large homogenous irregular soft tissue mass occupying the right orbital cavity with extension to the right lateral rectus, lacrimal gland, cavernous sinus, optic nerve and brain parenchyma; findings were suggestive of orbital rhabdomyosarcoma with intracranial extension. The patient was discharged against medical advice. She re-presented 7 weeks later with a much larger mass which had multiple friable bleeding sites. With much assurance by the oncologists, she had several blood transfusions and 6 courses of chemotherapy. Tumour regression was very impressive. Incisional biopsy and histology confirmed rhabdomyosarcoma with chemotherapeutic changes. The patient was stable and so referred to another tertiary center for External Beam Radiation Therapy (EBRT), but this was delayed due to financial constraints. Two months from her referral for EBRT, colleagues reported she died of intractable seizures
 Recommendations: This study is based on suggestions that therapeutic success for rhabdomyosarcoma is better in children with survival rates reaching 75% unlike in adults where prognosis is poor.1 In this report, remission was observed soon after commencement of treatment. Therefore, it is recommended that early diagnosis be done to improve outcomes. Secondly, combination drugs should be used in all rhabdomyosarcoma cases. Lastly, government policies geared towards universal health coverage should be made and implemented.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135148270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trichobezoar, An Unusual Cause of Small Bowel Obstruction in Pediatrics Age Group 毛癣:儿科年龄组小肠梗阻的一种罕见病因
Pub Date : 2023-10-03 DOI: 10.47672/ajhmn.1601
Farooque Ahmed Khan, Ammar Almashhadi, Nadeem Haider
Purpose: Trichobezoar, is a ball of swallowed hair, which is usually found in the stomach with a possibility of extension to the duodenum. As the tail can propagate to the small intestine, it is also given the name “Rapunzel syndrome”. The primary aim of this paper is to highlight an uncommon cause of intestinal obstruction in children and to share our experience of management in one of the youngest children reported in the literature. The secondary aim is to share a review of literature on this topic. Methodology: The hospital case notes of our patient were thoroughly reviewed and detailed history was confirmed with the family. Radiological imaging was discussed with a senior radiologist. We report a 3-year-old African child who presented to our emergency department with signs and symptoms of acute intestinal obstruction. Findings: After a thorough review of the literature, we document that ours is the second report of trichobezoar causing small intestinal obstruction in a 3-year-old child. At laparotomy, a 25 cm long trichobezoar was removed from the ileum with an enterotomy. Recommendations: Although it is a rare and unusual cause of isolated small bowel obstruction but with prompt diagnosis and timely intervention the outcome is excellent.
目的:毛粪,是一种吞下的毛球,通常在胃中发现,有可能延伸到十二指肠。由于尾巴可以繁殖到小肠,因此也被称为“长发公主综合征”。本文的主要目的是强调儿童肠梗阻的一种不常见的原因,并分享我们在文献中报道的最小的儿童之一的管理经验。第二个目的是分享关于这个主题的文献综述。方法:全面查阅患者的医院病例记录,并与家属确认详细病史。与一位资深放射科医生讨论了放射成像。我们报告一名3岁的非洲儿童因急性肠梗阻的症状和体征来到我们的急诊科。研究结果:经过对文献的全面回顾,我们发现这是第二例3岁儿童因毛粪引起小肠梗阻的报告。在剖腹手术中,通过肠切开术从回肠中取出25厘米长的毛粪。 建议:虽然这是一种罕见和不寻常的孤立性小肠阻塞的原因,但及时诊断和及时干预的结果是很好的。
{"title":"Trichobezoar, An Unusual Cause of Small Bowel Obstruction in Pediatrics Age Group","authors":"Farooque Ahmed Khan, Ammar Almashhadi, Nadeem Haider","doi":"10.47672/ajhmn.1601","DOIUrl":"https://doi.org/10.47672/ajhmn.1601","url":null,"abstract":"Purpose: Trichobezoar, is a ball of swallowed hair, which is usually found in the stomach with a possibility of extension to the duodenum. As the tail can propagate to the small intestine, it is also given the name “Rapunzel syndrome”. The primary aim of this paper is to highlight an uncommon cause of intestinal obstruction in children and to share our experience of management in one of the youngest children reported in the literature. The secondary aim is to share a review of literature on this topic.
 Methodology: The hospital case notes of our patient were thoroughly reviewed and detailed history was confirmed with the family. Radiological imaging was discussed with a senior radiologist. We report a 3-year-old African child who presented to our emergency department with signs and symptoms of acute intestinal obstruction.
 Findings: After a thorough review of the literature, we document that ours is the second report of trichobezoar causing small intestinal obstruction in a 3-year-old child. At laparotomy, a 25 cm long trichobezoar was removed from the ileum with an enterotomy.
 Recommendations: Although it is a rare and unusual cause of isolated small bowel obstruction but with prompt diagnosis and timely intervention the outcome is excellent.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135738755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Approach to a Child with Bilateral Proptosis as a Rare Presentation of Acute Myeloid Leukemia 一例罕见的急性髓系白血病患儿双侧突出的治疗方法
Pub Date : 2023-10-02 DOI: 10.47672/ajhmn.1600
Shafiq Tanveer, Maryum Khilji, Rao Hassan, Safina Tanveer, Ayesha Khilji
A 6-year-old girl presented with a 2-month history of sudden onset, painless, progressively increasing bilateral proptosis, palpable lymphadenopathy and skin pallor. A full blood count showed bicytopenia and the erythrocyte sedimentation rate (ESR) was raised. Computerized tomography (CT) scan showed bilateral lacrimal gland enlargement. The bone marrow biopsy was consistent with M2 acute myeloid leukemia (AML). The patient received symptomatic treatment and was sent to pediatric oncologist for induction chemotherapy and tumor lysis syndrome (TLS) protocol. Bilateral proptosis is a rare manifestation of several diseases. This case report emphasizes on the low threshold for hematological malignancies in the presentation of bilateral proptosis. Ophthalmologists should be cognizant of the unusual ophthalmic manifestations of haematological malignancies, as they are a diagnostic challenge but knowledge about the rare extramedullary manifestations of AML facilitates early diagnosis and thereby improves prognosis. Categories: Ophthalmology, Pediatrics, Hematology
一名6岁女孩,表现为2个月的突然发病,无痛,渐进性双侧突出,可触及的淋巴结病和皮肤苍白。全血细胞计数显示双氧体减少和红细胞沉降率(ESR)升高。CT扫描显示双侧泪腺肿大。骨髓活检符合M2型急性髓性白血病(AML)。对症治疗后送儿科肿瘤科进行诱导化疗及肿瘤溶解综合征(TLS)治疗方案。双侧突出是几种疾病的罕见表现。本病例报告强调双侧突出表现为血液系统恶性肿瘤的低阈值。眼科医生应该认识到血液系统恶性肿瘤的不寻常的眼部表现,因为它们是一个诊断挑战,但了解AML罕见的髓外表现有助于早期诊断,从而改善预后。 分类:眼科,儿科,血液学
{"title":"Approach to a Child with Bilateral Proptosis as a Rare Presentation of Acute Myeloid Leukemia","authors":"Shafiq Tanveer, Maryum Khilji, Rao Hassan, Safina Tanveer, Ayesha Khilji","doi":"10.47672/ajhmn.1600","DOIUrl":"https://doi.org/10.47672/ajhmn.1600","url":null,"abstract":"A 6-year-old girl presented with a 2-month history of sudden onset, painless, progressively increasing bilateral proptosis, palpable lymphadenopathy and skin pallor. A full blood count showed bicytopenia and the erythrocyte sedimentation rate (ESR) was raised. Computerized tomography (CT) scan showed bilateral lacrimal gland enlargement. The bone marrow biopsy was consistent with M2 acute myeloid leukemia (AML). The patient received symptomatic treatment and was sent to pediatric oncologist for induction chemotherapy and tumor lysis syndrome (TLS) protocol. Bilateral proptosis is a rare manifestation of several diseases. This case report emphasizes on the low threshold for hematological malignancies in the presentation of bilateral proptosis. Ophthalmologists should be cognizant of the unusual ophthalmic manifestations of haematological malignancies, as they are a diagnostic challenge but knowledge about the rare extramedullary manifestations of AML facilitates early diagnosis and thereby improves prognosis.
 Categories: Ophthalmology, Pediatrics, Hematology","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"233 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135829932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of Iliotibial Band Tightness and Its Association with Anterior Knee Pain in Healthcare Workers 医护人员髂胫束紧绷频率及其与前膝关节疼痛的关系
Pub Date : 2023-10-01 DOI: 10.47672/ajhmn.1599
Khushboo Humayun, Daniyal Siddiqi, Irtasam Ahmad, Saira Ajmal, Ayesha Iftikhar, Hafiz Maqsood, Kaiynat Shafique, Tamjeed Ghaffar
Purpose: Iliotibial band tightness can raise the risk of injury by altering biomechanics. ITB tightness leads to abnormal patellar alignment and tracking and causes pain and several other problems. To assess the frequency of iliotibial band tightness and its relation with anterior knee pain in health-care workers Methodology: It was a cross-sectional research conducted from September 2021 to February 2022. Sample size of the study was 210. Study settings included the government and private hospitals of Faisalabad. In order to recruit healthcare providers, a convenient sampling technique was utilized. Inclusion criteria of the study were both male and female healthcare workers of age between 21 to 45 years working from at least 2 years. Ober's test was used to determine the tightness of the IT band. The anterior knee pain was evaluated by numeric pain rating scale (NPRS). Data was analyzed and interpreted by SPSS version 25. Data was presented in forms of tables and charts. Findings: Out of 210 subjects, 64.76% were men and 35.23% were women. Iliotibial tightness was found to be present in 110(52.38%). On NPRS, 100(47.61%) participants reported mild to moderate pain and 30(14.28%) reported severe to worst pain in the anterior knee. Chi-square tests shows a statistical significant association (p<0.05) between iliotibial band and anterior knee pain. Recommendations: In conclusion, iliotibial tightness was found to be present in 52.38% of the health workers. Results of the study showed that anterior knee pain occurs in iliotibial band tightness. This study, grounded in biomechanical and anatomical theories, demonstrated a significant association between iliotibial band tightness and anterior knee pain. Healthcare workers should focus on proper body biomechanics and incorporate regular muscle stretching in their routine to prevent the muscle tightness and associated problems.
目的:髂胫束紧绷可通过改变生物力学而增加损伤的风险。腰束紧致导致异常的髌骨排列和追踪,并引起疼痛和其他一些问题。探讨医护人员髂胫束紧度频率及其与前膝关节疼痛的关系[#x0D];方法:这是一项横断面研究,于2021年9月至2022年2月进行。本研究的样本量为210人。研究环境包括费萨拉巴德的政府医院和私立医院。为了招募医疗保健提供者,采用了一种方便的抽样技术。研究的纳入标准是年龄在21至45岁之间、工作至少2年的男性和女性卫生保健工作者。奥伯氏测试用于确定IT带的松紧度。采用数值疼痛评定量表(NPRS)对膝关节前侧疼痛进行评定。数据分析和解释采用SPSS 25版本。数据以表格和图表的形式呈现。 结果:210名受试者中,男性占64.76%,女性占35.23%。110例(52.38%)存在髂胫紧张性。在NPRS测试中,100名(47.61%)参与者报告轻度至中度疼痛,30名(14.28%)报告膝关节前侧重度至重度疼痛。卡方检验显示髂胫束与膝关节前疼痛之间有统计学意义(p<0.05)。建议:总而言之,52.38%的卫生工作者存在髂胫紧绷。研究结果表明,膝关节前侧疼痛发生于髂胫束紧绷。这项基于生物力学和解剖学理论的研究表明,髂胫束紧绷与膝关节前侧疼痛之间存在显著关联。医护人员应关注适当的身体生物力学,并在日常工作中纳入有规律的肌肉拉伸,以防止肌肉紧绷和相关问题。
{"title":"Frequency of Iliotibial Band Tightness and Its Association with Anterior Knee Pain in Healthcare Workers","authors":"Khushboo Humayun, Daniyal Siddiqi, Irtasam Ahmad, Saira Ajmal, Ayesha Iftikhar, Hafiz Maqsood, Kaiynat Shafique, Tamjeed Ghaffar","doi":"10.47672/ajhmn.1599","DOIUrl":"https://doi.org/10.47672/ajhmn.1599","url":null,"abstract":"Purpose: Iliotibial band tightness can raise the risk of injury by altering biomechanics. ITB tightness leads to abnormal patellar alignment and tracking and causes pain and several other problems. To assess the frequency of iliotibial band tightness and its relation with anterior knee pain in health-care workers&#x0D; Methodology: It was a cross-sectional research conducted from September 2021 to February 2022. Sample size of the study was 210. Study settings included the government and private hospitals of Faisalabad. In order to recruit healthcare providers, a convenient sampling technique was utilized. Inclusion criteria of the study were both male and female healthcare workers of age between 21 to 45 years working from at least 2 years. Ober's test was used to determine the tightness of the IT band. The anterior knee pain was evaluated by numeric pain rating scale (NPRS). Data was analyzed and interpreted by SPSS version 25. Data was presented in forms of tables and charts.&#x0D; Findings: Out of 210 subjects, 64.76% were men and 35.23% were women. Iliotibial tightness was found to be present in 110(52.38%). On NPRS, 100(47.61%) participants reported mild to moderate pain and 30(14.28%) reported severe to worst pain in the anterior knee. Chi-square tests shows a statistical significant association (p<0.05) between iliotibial band and anterior knee pain.&#x0D; Recommendations: In conclusion, iliotibial tightness was found to be present in 52.38% of the health workers. Results of the study showed that anterior knee pain occurs in iliotibial band tightness. This study, grounded in biomechanical and anatomical theories, demonstrated a significant association between iliotibial band tightness and anterior knee pain. Healthcare workers should focus on proper body biomechanics and incorporate regular muscle stretching in their routine to prevent the muscle tightness and associated problems.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hip Flexors Shortening among Patients with Low Back Pain 腰痛患者髋屈肌缩短
Pub Date : 2023-10-01 DOI: 10.47672/ajhmn.1598
Amen Shahid, Faryal Kashif, Faiza Asghar, Farooq Islam, Asim Raza
Purpose: Determine the hip flexors shortening in individuals with low back pain. Methodology: It was descriptive cross-sectional study. A total of 255 participants were included according to the selection criteria. Non-probability sampling technique was used to select participants. Inclusion criteria of the study were the patients of age between 18 to 65 years having low back pain from a period of 3 months or more. Exclusion criteria were the individuals with history of spinal trauma, joint dysfunction in past 3 months, any congenital deformity in hip or lumbar region, any history of fracture in related joints in previous 6 months and history of abdominal, hip or lumbar surgery in previous 3 months. Study settings include OPD of DHQ hospital, Gujranwala and Physical therapy department of Gondal hospital, Gujranwala. Study was completed within 4 month. Thomas test was used to assess hip flexors shortening. A structured questionnaire was used to collect participants’ relevant data. Data was analysed by SPSS version 20. Findings: Mean age of the patients was 40.10±12.31 and mean body mass index was 27.44±6.10. Out of 255 patients, 35.7% were male and 64.3% were females. 64.3% participants were housewife, 20.8% were labour and 14.9% were worker. Thomas test was found to be positive in 63.5% patients of low back pain and negative in 36.5% patients. Chi square shows that (p>0.05) there was no significant association between participants’ gender and the results of Thomas test. But a statistically significant association was found between gender and occupation (p<0.05). Recommendations: In conclusion, hip flexor shortening was prevalent in patients of low back pain. The prevalence of hip flexor muscles shortening was found to be 63.5%. There was no statistical significant association of participants’ gender with hip flexor shortening. However, statistical significant association was found between gender and occupation of the participant with low back pain. The relationship of hip flexor shortening with various conditions should be evaluated in future research with a bigger sample size, diverse populations, and different age groups. It is suggested that future research look at the prevalence of hip flexor shortening in those without LBP. To stop people's muscles from shortening in general, several awareness programmes for posture advice and muscle stretching practices should be set up.
目的:确定下腰痛患者髋屈肌缩短情况。 方法:采用描述性横断面研究。根据评选标准,共有255人入选。采用非概率抽样技术选择参与者。该研究的纳入标准是年龄在18至65岁之间,腰痛持续3个月或更长时间的患者。排除标准为:过去3个月有脊柱外伤史、关节功能障碍史、髋关节或腰椎先天性畸形史、过去6个月有相关关节骨折史、过去3个月有腹部、髋关节或腰椎手术史。研究环境包括古吉兰瓦拉DHQ医院的门诊和古吉兰瓦拉Gondal医院的物理治疗科。研究在4个月内完成。托马斯试验用于评估髋屈肌缩短。采用结构化问卷收集参与者的相关数据。数据分析采用SPSS version 20. 结果:患者平均年龄40.10±12.31岁,平均体重指数27.44±6.10。255例患者中男性占35.7%,女性占64.3%。64.3%的受访者为家庭主妇,20.8%为劳工,14.9%为工人。63.5%的腰痛患者thomastest阳性,36.5%的腰痛患者thomastest阴性。卡方分析显示(p>0.05)被试性别与Thomas检验结果无显著相关。但性别与职业之间存在统计学上显著的关联(p<0.05)。建议:总之,髋屈肌缩短在腰痛患者中很普遍。髋屈肌缩短的发生率为63.5%。参与者的性别与髋屈肌缩短没有统计学上的显著关联。然而,腰痛患者的性别和职业之间存在显著的统计学关联。髋屈肌缩短与各种疾病的关系应在未来更大样本量、不同人群和不同年龄组的研究中进行评估。建议未来的研究着眼于无腰痛患者髋屈肌缩短的患病率。为了防止人们的肌肉普遍缩短,应该建立一些姿势建议和肌肉拉伸练习的意识项目。
{"title":"Hip Flexors Shortening among Patients with Low Back Pain","authors":"Amen Shahid, Faryal Kashif, Faiza Asghar, Farooq Islam, Asim Raza","doi":"10.47672/ajhmn.1598","DOIUrl":"https://doi.org/10.47672/ajhmn.1598","url":null,"abstract":"Purpose: Determine the hip flexors shortening in individuals with low back pain.&#x0D; Methodology: It was descriptive cross-sectional study. A total of 255 participants were included according to the selection criteria. Non-probability sampling technique was used to select participants. Inclusion criteria of the study were the patients of age between 18 to 65 years having low back pain from a period of 3 months or more. Exclusion criteria were the individuals with history of spinal trauma, joint dysfunction in past 3 months, any congenital deformity in hip or lumbar region, any history of fracture in related joints in previous 6 months and history of abdominal, hip or lumbar surgery in previous 3 months. Study settings include OPD of DHQ hospital, Gujranwala and Physical therapy department of Gondal hospital, Gujranwala. Study was completed within 4 month. Thomas test was used to assess hip flexors shortening. A structured questionnaire was used to collect participants’ relevant data. Data was analysed by SPSS version 20.&#x0D; Findings: Mean age of the patients was 40.10±12.31 and mean body mass index was 27.44±6.10. Out of 255 patients, 35.7% were male and 64.3% were females. 64.3% participants were housewife, 20.8% were labour and 14.9% were worker. Thomas test was found to be positive in 63.5% patients of low back pain and negative in 36.5% patients. Chi square shows that (p>0.05) there was no significant association between participants’ gender and the results of Thomas test. But a statistically significant association was found between gender and occupation (p<0.05).&#x0D; Recommendations: In conclusion, hip flexor shortening was prevalent in patients of low back pain. The prevalence of hip flexor muscles shortening was found to be 63.5%. There was no statistical significant association of participants’ gender with hip flexor shortening. However, statistical significant association was found between gender and occupation of the participant with low back pain. The relationship of hip flexor shortening with various conditions should be evaluated in future research with a bigger sample size, diverse populations, and different age groups. It is suggested that future research look at the prevalence of hip flexor shortening in those without LBP. To stop people's muscles from shortening in general, several awareness programmes for posture advice and muscle stretching practices should be set up.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarkers for Prediabetes, Type 2 Diabetes, and Associated Complications 糖尿病前期、2型糖尿病及相关并发症的生物标志物
Pub Date : 2023-09-27 DOI: 10.47672/ajhmn.1592
Ali Almheiri, Amna Alhammadi, Fatima AlShehhi, Asma Mohammad, Rodha Alshamsi, Khaled Alzaman, Saima Jabeen, Burhan Haq
Purpose: Diabetes mellitus is a chronic disorder caused by high blood glucose levels due to insulin resistance or insufficient insulin production in pancreatic β-cells. Due to its fastest-growing public health concerns worldwide, it is important to evaluate metabolic profile abnormalities before pre-diabetes or T2DM to anticipate and prevent disease progression. The purpose of the study was to examine the metabolite biomarkers by systematic review and meta-analysis to support early detection of pre-diabetes and T2DM. Methodology: Studies published from the earliest online through May 31, 2023, were searched in the Cochrane Library, EMBASE, PubMed, and Scopus. Article titles, abstracts, and complete texts were reviewed after duplicate records were eliminated. Two writers (Long and Yang) created the following inclusion criteria for the publications before literature screening: The study was conducted on humans, did not involve gestational diabetes mellitus (GDM), type 1 diabetes mellitus (T1DM), or subjects under 18 years old, included a diabetic or prediabetes group, and followed international diagnostic guidelines (American Diabetes Association, 2013). Findings: The study aimed to review the biomarkers that have been utilized for diabetes in previous research. The comparison of the biomarkers mentioned in the provided information revealed a complex interplay of factors influencing the risk and management of Type 2 Diabetes (T2D). These biomarkers encompass genetic, lifestyle, environmental, and insulin-related factors, each with varying degrees of accuracy and specificity in predicting T2D risk or guiding its management. Recommendations: The research will help in spreading awareness among people regarding the identification of diabetes as understanding biomarker-based screening's economic impact can inform healthcare policies. Future studies should validate these biomarkers' diagnostic capacities across varied populations and circumstances. Assessment of these biomarkers' predictive usefulness should be done over time via longitudinal research. Understanding biomarker alterations and diabetes progression improves risk prediction.
目的:糖尿病是由胰岛素抵抗或胰腺β细胞胰岛素分泌不足引起的高血糖引起的慢性疾病。由于其在全球范围内增长最快的公共卫生问题,在糖尿病前期或2型糖尿病之前评估代谢谱异常对于预测和预防疾病进展非常重要。本研究的目的是通过系统评价和荟萃分析来检测代谢物生物标志物,以支持糖尿病前期和T2DM的早期检测。方法:从最早的在线发表的研究到2023年5月31日,在Cochrane图书馆、EMBASE、PubMed和Scopus中进行检索。消除重复记录后,对文章标题、摘要和全文进行审查。两位作者(Long和Yang)在文献筛选之前为出版物创建了以下纳入标准:研究对象为人类,不涉及妊娠期糖尿病(GDM)、1型糖尿病(T1DM)或18岁以下的受试者,包括糖尿病或糖尿病前期组,并遵循国际诊断指南(美国糖尿病协会,2013)。研究结果:本研究旨在回顾以往研究中用于糖尿病的生物标志物。所提供信息中提到的生物标志物的比较揭示了影响2型糖尿病(T2D)风险和管理的因素之间复杂的相互作用。这些生物标志物包括遗传、生活方式、环境和胰岛素相关因素,每一个在预测T2D风险或指导其管理方面都具有不同程度的准确性和特异性。 建议:这项研究将有助于在人们中传播关于糖尿病识别的意识,因为了解基于生物标志物的筛查的经济影响可以为医疗保健政策提供信息。未来的研究应该验证这些生物标志物在不同人群和环境中的诊断能力。随着时间的推移,这些生物标记物的预测效用应该通过纵向研究来评估。了解生物标志物改变和糖尿病进展可改善风险预测。
{"title":"Biomarkers for Prediabetes, Type 2 Diabetes, and Associated Complications","authors":"Ali Almheiri, Amna Alhammadi, Fatima AlShehhi, Asma Mohammad, Rodha Alshamsi, Khaled Alzaman, Saima Jabeen, Burhan Haq","doi":"10.47672/ajhmn.1592","DOIUrl":"https://doi.org/10.47672/ajhmn.1592","url":null,"abstract":"Purpose: Diabetes mellitus is a chronic disorder caused by high blood glucose levels due to insulin resistance or insufficient insulin production in pancreatic β-cells. Due to its fastest-growing public health concerns worldwide, it is important to evaluate metabolic profile abnormalities before pre-diabetes or T2DM to anticipate and prevent disease progression. The purpose of the study was to examine the metabolite biomarkers by systematic review and meta-analysis to support early detection of pre-diabetes and T2DM.&#x0D; Methodology: Studies published from the earliest online through May 31, 2023, were searched in the Cochrane Library, EMBASE, PubMed, and Scopus. Article titles, abstracts, and complete texts were reviewed after duplicate records were eliminated. Two writers (Long and Yang) created the following inclusion criteria for the publications before literature screening: The study was conducted on humans, did not involve gestational diabetes mellitus (GDM), type 1 diabetes mellitus (T1DM), or subjects under 18 years old, included a diabetic or prediabetes group, and followed international diagnostic guidelines (American Diabetes Association, 2013).&#x0D; Findings: The study aimed to review the biomarkers that have been utilized for diabetes in previous research. The comparison of the biomarkers mentioned in the provided information revealed a complex interplay of factors influencing the risk and management of Type 2 Diabetes (T2D). These biomarkers encompass genetic, lifestyle, environmental, and insulin-related factors, each with varying degrees of accuracy and specificity in predicting T2D risk or guiding its management.&#x0D; Recommendations: The research will help in spreading awareness among people regarding the identification of diabetes as understanding biomarker-based screening's economic impact can inform healthcare policies. Future studies should validate these biomarkers' diagnostic capacities across varied populations and circumstances. Assessment of these biomarkers' predictive usefulness should be done over time via longitudinal research. Understanding biomarker alterations and diabetes progression improves risk prediction.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135536747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of De-Quervain’s Tenosynovitis in Tailors of Multan (Punjab) 木尔坦(旁遮普省)裁缝德-奎尔凡氏腱鞘炎患病率
Pub Date : 2023-09-26 DOI: 10.47672/ajhmn.1590
Rabia Khan, Babar Ali, Zulaikha Saif, Faisal Ishfaq, Athar Saeed, Sheeza Rubab, Shahbaz Khizar
Purpose: De Quervain's Tenosynovitis is inflammation of extensor pollicis brevis and abductor pollicis longus tendons that run from the side of the wrist to the base of the thumb. To see the frequency of De Quervain’s Tenosynovitis and work related risk factors in tailors of Multan, Pakistan Methodology: It was a cross-sectional study. Sample size of the research was 246. Study was conducted at the city of Pakistan, Multan. Inclusion criteria of the study were tailors of age between twenty to fifty years having experience of more than 3 years. Data was collected to the selected population, through convenient sampling technique. Duration of the study was 8 months. Outcome measures of the study were Finkelstein test, Visual analogue scale and a structured questionnaire. The collected data was analyzed by using SPSS version 25. Findings: Out of 246 participants, 72.3% were males and 27.6% were females. Prevalence of De Quervain's Tenosynovitis was found to be 64% in tailors of Multan through Finkelstein test. 25.6% of the participants had moderate, while 22.3% had extreme discomfort in lower back. 35.3% reported to have mild discomfort in arms. 52.4% had mild to moderate discomfort in wrist or hand. 19.91% reported not to have an enough space for work. 44.30% did not have adjustable chairs. 69.91% reported to have no back rest while sewing, 63% reported unavailability of foot rest and 64.63% had no arm rest while sewing. Recommendations: De Quervain’s Tenosynovitis is prevalent in tailors of Multan, Pakistan. Work-related discomfort was found in various regions of body including eyes, neck, shoulders, arms, wrist and hand. Chairs with no adjustable height, unavailability of arm and foot rest and no back support were associated work related risk factors in tailors.
目的:De Quervain's腱鞘炎是指拇短伸肌腱和拇长外展肌腱的炎症,从腕侧到拇指基部。了解巴基斯坦木尔坦地区裁缝德奎尔文氏腱鞘炎发病频率及工作相关危险因素 方法:这是一项横断面研究。该研究的样本量为246。研究是在巴基斯坦木尔坦市进行的。该研究的纳入标准是年龄在20至50岁之间,经验超过3年的裁缝。通过方便的抽样技术,对选定的人群收集数据。研究时间为8个月。结果测量采用Finkelstein检验、视觉模拟量表和结构化问卷。收集的数据采用SPSS 25版进行分析。 研究结果:246名参与者中,72.3%为男性,27.6%为女性。通过Finkelstein试验发现木尔坦地区裁缝的De Quervain氏腱鞘炎患病率为64%。25.6%的参与者有中度不适,而22.3%的参与者有下背部极度不适。35.3%的人报告手臂有轻微不适。52.4%的患者有轻至中度手腕或手部不适。19.91%的人表示没有足够的工作空间。44.30%没有可调节的椅子。69.91%报告缝纫时没有靠背,63%报告缝纫时没有脚凳,64.63%报告缝纫时没有扶手。 建议:De Quervain氏腱鞘炎在巴基斯坦木尔坦的裁缝中很流行。与工作相关的不适出现在身体的各个部位,包括眼睛、脖子、肩膀、手臂、手腕和手。没有可调节高度的椅子,没有扶手和脚架,没有背部支撑,这些都是裁缝工作相关的危险因素。
{"title":"Prevalence of De-Quervain’s Tenosynovitis in Tailors of Multan (Punjab)","authors":"Rabia Khan, Babar Ali, Zulaikha Saif, Faisal Ishfaq, Athar Saeed, Sheeza Rubab, Shahbaz Khizar","doi":"10.47672/ajhmn.1590","DOIUrl":"https://doi.org/10.47672/ajhmn.1590","url":null,"abstract":"Purpose: De Quervain's Tenosynovitis is inflammation of extensor pollicis brevis and abductor pollicis longus tendons that run from the side of the wrist to the base of the thumb. To see the frequency of De Quervain’s Tenosynovitis and work related risk factors in tailors of Multan, Pakistan&#x0D; Methodology: It was a cross-sectional study. Sample size of the research was 246. Study was conducted at the city of Pakistan, Multan. Inclusion criteria of the study were tailors of age between twenty to fifty years having experience of more than 3 years. Data was collected to the selected population, through convenient sampling technique. Duration of the study was 8 months. Outcome measures of the study were Finkelstein test, Visual analogue scale and a structured questionnaire. The collected data was analyzed by using SPSS version 25.&#x0D; Findings: Out of 246 participants, 72.3% were males and 27.6% were females. Prevalence of De Quervain's Tenosynovitis was found to be 64% in tailors of Multan through Finkelstein test. 25.6% of the participants had moderate, while 22.3% had extreme discomfort in lower back. 35.3% reported to have mild discomfort in arms. 52.4% had mild to moderate discomfort in wrist or hand. 19.91% reported not to have an enough space for work. 44.30% did not have adjustable chairs. 69.91% reported to have no back rest while sewing, 63% reported unavailability of foot rest and 64.63% had no arm rest while sewing.&#x0D; Recommendations: De Quervain’s Tenosynovitis is prevalent in tailors of Multan, Pakistan. Work-related discomfort was found in various regions of body including eyes, neck, shoulders, arms, wrist and hand. Chairs with no adjustable height, unavailability of arm and foot rest and no back support were associated work related risk factors in tailors.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134960380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Use of Diabetic Medications for Non-Diabetic Conditions: A Comprehensive Literature Review 探讨糖尿病药物在非糖尿病疾病中的应用:综合文献综述
Pub Date : 2023-09-20 DOI: 10.47672/ajhmn.1586
Rosemary O. Iriowen, Temituoyo F. Edema, Victor O. Dike, Taiwo I. Ogundipe, Ifeoluwa O. Oluwatowoju, Bright C. Nwatamole, Ogochukwu A. Okonkwo, Okelue E. Okobi
Purpose: Currently, a significant portion of the US population has been impacted by diabetes, and alongside it, heart failure, chronic kidney disease (CKD), obesity, and non-alcoholic fatty liver disease (NAFLD) rates are on the rise. Recent research has highlighted the potential of antidiabetic medications to extend beyond diabetes management. This literature review is aimed at exploring the evolving roles of GLP-1 receptor agonists, SGLT2 inhibitors, and thiazolidinediones. It specifically investigates their applications in cardiovascular disease, chronic kidney disease (CKD), obesity, polycystic ovarian syndrome (PCOS), and NAFLD. As a novel therapeutic approach, their application could reshape treatment strategies for interconnected metabolic disorders, offering a new horizon in patient care. Methodology: We conducted a comprehensive search of PubMed and Google Scholar for English-language studies published in the United States and Canada between January 1st, 2013, and August 31st, 2023 focusing on trials involving GLP-1RA, SGLT-2i, and thiazolidinediones therapy. Findings: In our study, GLP-1 receptor agonists emerged as multifaceted pharmaceutical agents, showcasing improvements in cardiovascular disease outcomes, nephroprotective effects, substantial efficacy in obesity management, and promising prospects in addressing non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS). Additionally, thiazolidinediones displayed effectiveness in the management of non-alcoholic steatohepatitis (NASH), while metformin exhibited notable benefits in PCOS management. Furthermore, Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors demonstrated remarkable advancements, particularly in terms of cardiovascular and renal benefits. Our findings emphasize the diverse and evolving applications of diabetic medications in addressing a wide range of chronic medical conditions, ultimately leading to enhanced patient care and improved outcomes. Recommendations: We recommend that healthcare practitioners carefully consider the expanded utility of these medications beyond their conventional diabetic indications and explore their integration into treatment strategies for the indicated medical conditions. This should be done while thoughtfully weighing the associated risks and benefits to ensure the most effective and safe patient care possible.
目的:目前,美国有相当一部分人口受到糖尿病的影响,与此同时,心力衰竭、慢性肾脏疾病(CKD)、肥胖和非酒精性脂肪性肝病(NAFLD)的发病率也在上升。最近的研究强调了抗糖尿病药物在糖尿病管理之外的潜力。本文献综述旨在探讨GLP-1受体激动剂、SGLT2抑制剂和噻唑烷二酮类药物的作用演变。它特别研究了它们在心血管疾病、慢性肾脏疾病(CKD)、肥胖、多囊卵巢综合征(PCOS)和NAFLD中的应用。作为一种新的治疗方法,它们的应用可以重塑相互关联的代谢紊乱的治疗策略,为患者护理提供新的视野。 方法:我们对2013年1月1日至2023年8月31日期间在美国和加拿大发表的英语研究进行了PubMed和Google Scholar的全面搜索,重点是涉及GLP-1RA、SGLT-2i和噻唑烷二酮类药物治疗的试验。& # x0D;研究结果:在我们的研究中,GLP-1受体激动剂作为多方面的药物制剂出现,显示出心血管疾病结局的改善、肾保护作用、肥胖管理的实质性功效,以及在治疗非酒精性脂肪性肝病(NAFLD)和多囊卵巢综合征(PCOS)方面的良好前景。此外,噻唑烷二酮类药物在治疗非酒精性脂肪性肝炎(NASH)方面显示出有效性,而二甲双胍在治疗PCOS方面显示出显著的益处。此外,钠-葡萄糖共转运蛋白-2 (SGLT2)抑制剂表现出显著的进步,特别是在心血管和肾脏方面的益处。我们的研究结果强调了糖尿病药物在解决各种慢性疾病方面的多样化和不断发展的应用,最终导致增强患者护理和改善结果。 建议:我们建议医疗保健从业人员仔细考虑这些药物在其常规糖尿病适应症之外的扩展效用,并探索将其整合到适应症的治疗策略中。这应该在仔细权衡相关风险和利益的同时进行,以确保尽可能最有效和安全的患者护理。
{"title":"Exploring the Use of Diabetic Medications for Non-Diabetic Conditions: A Comprehensive Literature Review","authors":"Rosemary O. Iriowen, Temituoyo F. Edema, Victor O. Dike, Taiwo I. Ogundipe, Ifeoluwa O. Oluwatowoju, Bright C. Nwatamole, Ogochukwu A. Okonkwo, Okelue E. Okobi","doi":"10.47672/ajhmn.1586","DOIUrl":"https://doi.org/10.47672/ajhmn.1586","url":null,"abstract":"Purpose: Currently, a significant portion of the US population has been impacted by diabetes, and alongside it, heart failure, chronic kidney disease (CKD), obesity, and non-alcoholic fatty liver disease (NAFLD) rates are on the rise. Recent research has highlighted the potential of antidiabetic medications to extend beyond diabetes management. This literature review is aimed at exploring the evolving roles of GLP-1 receptor agonists, SGLT2 inhibitors, and thiazolidinediones. It specifically investigates their applications in cardiovascular disease, chronic kidney disease (CKD), obesity, polycystic ovarian syndrome (PCOS), and NAFLD. As a novel therapeutic approach, their application could reshape treatment strategies for interconnected metabolic disorders, offering a new horizon in patient care.&#x0D; Methodology: We conducted a comprehensive search of PubMed and Google Scholar for English-language studies published in the United States and Canada between January 1st, 2013, and August 31st, 2023 focusing on trials involving GLP-1RA, SGLT-2i, and thiazolidinediones therapy. &#x0D; Findings: In our study, GLP-1 receptor agonists emerged as multifaceted pharmaceutical agents, showcasing improvements in cardiovascular disease outcomes, nephroprotective effects, substantial efficacy in obesity management, and promising prospects in addressing non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS). Additionally, thiazolidinediones displayed effectiveness in the management of non-alcoholic steatohepatitis (NASH), while metformin exhibited notable benefits in PCOS management. Furthermore, Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors demonstrated remarkable advancements, particularly in terms of cardiovascular and renal benefits. Our findings emphasize the diverse and evolving applications of diabetic medications in addressing a wide range of chronic medical conditions, ultimately leading to enhanced patient care and improved outcomes.&#x0D; Recommendations: We recommend that healthcare practitioners carefully consider the expanded utility of these medications beyond their conventional diabetic indications and explore their integration into treatment strategies for the indicated medical conditions. This should be done while thoughtfully weighing the associated risks and benefits to ensure the most effective and safe patient care possible.","PeriodicalId":7672,"journal":{"name":"American Journal of Health, Medicine and Nursing Practice","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136309608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
American Journal of Health, Medicine and Nursing Practice
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1