{"title":"Non-expression of Epithelial Membrane Antigen Protein is Diagnostic for Poorly Differentiated Oral Squamous Cell Carcinoma from Ibadan, Nigeria","authors":"K. Onyegbula, B. Emikpe, A. Adisa, C. Anumudu","doi":"10.5099/AJ210100019","DOIUrl":"https://doi.org/10.5099/AJ210100019","url":null,"abstract":"","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83909045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Apelin-13 Attenuates Ischemic Changes in A Rat Model of Myocardial Infarction via Increasing Circulating Angiogenic Factors","authors":"Mona A. Said","doi":"10.5099/AJ210100010","DOIUrl":"https://doi.org/10.5099/AJ210100010","url":null,"abstract":"","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84871257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study the Oral Toxicity of Zinc Oxide Nanoparticles in Adult Mice","authors":"R. S. S. Eldine","doi":"10.5099/AJ210100028","DOIUrl":"https://doi.org/10.5099/AJ210100028","url":null,"abstract":"","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80671151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Ebo, C. Ighodaro, W. Silas, Ogechukwu Emmanuel Aloamaka, Anthonia Odinika Chime
{"title":"Anti-Hypercholesterolemic and Hepatoprotective Effect of Aqueous Seed Extract of Carica Papaya in Rats Fed with Thermoxidized Palm Oil Diet","authors":"O. Ebo, C. Ighodaro, W. Silas, Ogechukwu Emmanuel Aloamaka, Anthonia Odinika Chime","doi":"10.5099/AJ210100044","DOIUrl":"https://doi.org/10.5099/AJ210100044","url":null,"abstract":"","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72992801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folorunso Timothy Oluwarotimi, Balogun Michael Olabode, O. Olaniyi
{"title":"Non Invasive Assessment of Left Ventricular Structure and Functions in Nigerians with Keloids","authors":"Folorunso Timothy Oluwarotimi, Balogun Michael Olabode, O. Olaniyi","doi":"10.5099/AJ210100001","DOIUrl":"https://doi.org/10.5099/AJ210100001","url":null,"abstract":"","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73833334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim� R. P. Ishimwe, Thierry Habyarimana, J. Mucumbitsi, Callixte Yadufashije, F. Niyonzima
{"title":"Association of Creatine Level and Hematological Parameters among Kidney Patients at Rwamagana Provincial Hoapital","authors":"Aim� R. P. Ishimwe, Thierry Habyarimana, J. Mucumbitsi, Callixte Yadufashije, F. Niyonzima","doi":"10.5099/AJ210100037","DOIUrl":"https://doi.org/10.5099/AJ210100037","url":null,"abstract":"","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80807022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Poornasha Mohabeer, I. Banerjee, Abishek Kashyap, Ananya Shukla, J. Robinson, N. D. Ramdhan
Background: SARS-CoV-2 is the highly infectious new coronavirus, which has been associated with the pandemic COVID-19. The majority of those pathogenic coronaviruses are benign, namely HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1, and they have been linked to common cases of flu. Two of these viruses namely SARS coronavirus and MERS coronavirus are known to have caused more severe infections. Based on phylogenetic analysis, the Coronaviruses are divided into four groups, which are: Alpha-CoV, Beta -CoV, Gamma-CoV, and Delta -CoV. The Beta- CoV genus is further classified into four lineages, which are referred to as Groups A, B, C, and D. At the genomic level, SARS-CoV-2 has been identified to match with the lineage B of Beta coronavirus. This infection affects the respiratory tract, mainly the lungs' alveoli, and can cause a wide variety of symptoms ranging from discharge from the nose and a sore throat to respiratory distress, septic shock, and failure of multiple organs. To date, millions of people have been affected by the virus. The current mortality rate is around 6%. Early diagnosis is essential to prevent the spread of the infection. An extensive literature review was done using Pubmed, Medline, Pubmed Central, Embase, Goggle Scholar databases from January 20, 2020, till October 20, 2020. Conclusion: COVID-19 is the third outbreak of a pathogenic human coronavirus, after MERS and SARS. Its high rate of transmissibility has taken a toll on citizens' personal and professional lives globally. The peculiarities of SARS-CoV-2, regarding its genomic uniqueness and the role of Malayan pangolins as intermediate hosts, still demands more research to determine the degree to which they partake in the generation of the pathogenicity and infectiousness of the virus.
{"title":"SARS-CoV-2 - an update in virology: A Narrative Review","authors":"Poornasha Mohabeer, I. Banerjee, Abishek Kashyap, Ananya Shukla, J. Robinson, N. D. Ramdhan","doi":"10.3126/jbs.v7i2.34007","DOIUrl":"https://doi.org/10.3126/jbs.v7i2.34007","url":null,"abstract":"Background: SARS-CoV-2 is the highly infectious new coronavirus, which has been associated with the pandemic COVID-19. The majority of those pathogenic coronaviruses are benign, namely HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1, and they have been linked to common cases of flu. Two of these viruses namely SARS coronavirus and MERS coronavirus are known to have caused more severe infections. Based on phylogenetic analysis, the Coronaviruses are divided into four groups, which are: Alpha-CoV, Beta -CoV, Gamma-CoV, and Delta -CoV. The Beta- CoV genus is further classified into four lineages, which are referred to as Groups A, B, C, and D. At the genomic level, SARS-CoV-2 has been identified to match with the lineage B of Beta coronavirus. This infection affects the respiratory tract, mainly the lungs' alveoli, and can cause a wide variety of symptoms ranging from discharge from the nose and a sore throat to respiratory distress, septic shock, and failure of multiple organs. To date, millions of people have been affected by the virus. The current mortality rate is around 6%. Early diagnosis is essential to prevent the spread of the infection. An extensive literature review was done using Pubmed, Medline, Pubmed Central, Embase, Goggle Scholar databases from January 20, 2020, till October 20, 2020. \u0000Conclusion: COVID-19 is the third outbreak of a pathogenic human coronavirus, after MERS and SARS. Its high rate of transmissibility has taken a toll on citizens' personal and professional lives globally. The peculiarities of SARS-CoV-2, regarding its genomic uniqueness and the role of Malayan pangolins as intermediate hosts, still demands more research to determine the degree to which they partake in the generation of the pathogenicity and infectiousness of the virus.","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82660795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Play is a tremendous method of communication, expansion of social relationship and communal understanding. Admission into the hospital leads to anxiety and strain for children due to alteration in the settings and their health conditions. Children suffer from separation anxiety; they are not cooperative and do not allow nurses to do any invasive procedures. So the study aimed to find out the anxiety level and role of art and play therapy to overcome it. Material and methods: Sixty preschool hospitalised children were selected for the study. Data were collected through a self-structured questionnaire on socio-demographic and hospitalisation anxiety scale. Descriptive and inferential statistics were used to analyse the data. Results: The study findings revealed that 75%, 20% and 5% of children had moderate, severe and mild anxiety during hospitalisation. There was a significant difference observed between pre-test and a post-test mean score of anxiety level in art and play therapy at p<0.0001. A significant relationship was observed between the duration of hospitalisation and anxiety level. Conclusion: The present study's findings conclude that art therapy and play therapy are cost-effective, convenient, and require less skill to reduce anxiety among hospitalised preschool children.
{"title":"Effect of art therapy and play therapy on anxiety among hospitalized preschool children","authors":"S. R. Dalei, G. Nayak, Rubi Pradhan","doi":"10.3126/jbs.v7i2.34006","DOIUrl":"https://doi.org/10.3126/jbs.v7i2.34006","url":null,"abstract":"Background: Play is a tremendous method of communication, expansion of social relationship and communal understanding. Admission into the hospital leads to anxiety and strain for children due to alteration in the settings and their health conditions. Children suffer from separation anxiety; they are not cooperative and do not allow nurses to do any invasive procedures. So the study aimed to find out the anxiety level and role of art and play therapy to overcome it. \u0000Material and methods: Sixty preschool hospitalised children were selected for the study. Data were collected through a self-structured questionnaire on socio-demographic and hospitalisation anxiety scale. Descriptive and inferential statistics were used to analyse the data. \u0000Results: The study findings revealed that 75%, 20% and 5% of children had moderate, severe and mild anxiety during hospitalisation. There was a significant difference observed between pre-test and a post-test mean score of anxiety level in art and play therapy at p<0.0001. A significant relationship was observed between the duration of hospitalisation and anxiety level. \u0000Conclusion: The present study's findings conclude that art therapy and play therapy are cost-effective, convenient, and require less skill to reduce anxiety among hospitalised preschool children.","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86534366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ananya Shukla, Pornasha Mohabeer, Abhishek Kashyap, J. Robinson, I. Banerjee
Background: In response to the urgency of increasing death toll due to COVID-19, caused due to SARS CoV-2, various drugs are under clinical trial, as there is no specific drug for its treatment. In an international survey that was recently conducted in which about 7500 physicians participated from all over the world considered that Hydroxychloroquine and Azithromycin were among the most effective ones for the pharmacotherapy of COVID-19. Azithromycin is a macrolide antibiotic whose mechanism of action against COVID-19 is still unknown, but various theories have been postulated. In vitro and in vivo studies have been conducted; however, their results are quite contradictory. Azithromycin is said to increase the risk of QT prolongation in elderly patients and when given in combination with Hydroxychloroquine can increase the risk of Torsade’s de pointes. Therefore, caution has to be paid before prescribing Azithromycin. Conclusion: The mass loss of human lives is regrettable and needs to be stopped as soon as possible. Azithromycin could be the future drug for COVID-19, but such limited data is insufficient to support the drug's safety or efficacy and needs to be reconsidered.
{"title":"Azithromycin and Hydroxychloroquine combination: The future pharmacotherapy of COVID-19","authors":"Ananya Shukla, Pornasha Mohabeer, Abhishek Kashyap, J. Robinson, I. Banerjee","doi":"10.3126/jbs.v7i2.33997","DOIUrl":"https://doi.org/10.3126/jbs.v7i2.33997","url":null,"abstract":"Background: In response to the urgency of increasing death toll due to COVID-19, caused due to SARS CoV-2, various drugs are under clinical trial, as there is no specific drug for its treatment. In an international survey that was recently conducted in which about 7500 physicians participated from all over the world considered that Hydroxychloroquine and Azithromycin were among the most effective ones for the pharmacotherapy of COVID-19. Azithromycin is a macrolide antibiotic whose mechanism of action against COVID-19 is still unknown, but various theories have been postulated. In vitro and in vivo studies have been conducted; however, their results are quite contradictory. Azithromycin is said to increase the risk of QT prolongation in elderly patients and when given in combination with Hydroxychloroquine can increase the risk of Torsade’s de pointes. Therefore, caution has to be paid before prescribing Azithromycin. \u0000Conclusion: The mass loss of human lives is regrettable and needs to be stopped as soon as possible. Azithromycin could be the future drug for COVID-19, but such limited data is insufficient to support the drug's safety or efficacy and needs to be reconsidered.","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77671068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 and neurological complications: Is it alarming?","authors":"B. Roy","doi":"10.3126/jbs.v7i2.33996","DOIUrl":"https://doi.org/10.3126/jbs.v7i2.33996","url":null,"abstract":"No abstract available.","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83018615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：