Pub Date : 2006-01-01DOI: 10.1016/j.yadr.2006.07.001
Daniel S. Loo MD
{"title":"Systemic Antifungal Agents: An Update of Established and New Therapies","authors":"Daniel S. Loo MD","doi":"10.1016/j.yadr.2006.07.001","DOIUrl":"10.1016/j.yadr.2006.07.001","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"22 ","pages":"Pages 101-124"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2006.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26510435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1016/j.yadr.2005.06.001
E. Victor Ross MD (Dermatology Department)
{"title":"Acne, Lasers, and Light","authors":"E. Victor Ross MD (Dermatology Department)","doi":"10.1016/j.yadr.2005.06.001","DOIUrl":"10.1016/j.yadr.2005.06.001","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"21 ","pages":"Pages 1-32"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2005.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25747831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1016/j.yadr.2005.04.001
Bernhard Homey MD (Department of Dermatology)
{"title":"Chemokines and Inflammatory Skin Diseases","authors":"Bernhard Homey MD (Department of Dermatology)","doi":"10.1016/j.yadr.2005.04.001","DOIUrl":"10.1016/j.yadr.2005.04.001","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"21 ","pages":"Pages 251-277"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2005.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25747842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1016/j.yadr.2005.04.003
Ruby Ghadially MBChB (Associate Professor of Dermatology)
{"title":"Epidermal Stem Cells","authors":"Ruby Ghadially MBChB (Associate Professor of Dermatology)","doi":"10.1016/j.yadr.2005.04.003","DOIUrl":"10.1016/j.yadr.2005.04.003","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"21 ","pages":"Pages 335-355"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2005.04.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25747845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1016/j.yadr.2005.07.001
Orr Barak PhD (Medical Student) , James R. Treat MD (Resident) , William D. James MD (Paul R. Gross Professor of Dermatology; Vice Chairman and Residency Program Director)
The ability of the cutaneous barrier to help defend the body against pathogens relies on both acquired and innate immune responses. Recently, a large body of research has suggested that a critical component of the innate immune response in the skin is 3 antimicrobial peptides: the cathelicidins, defensins, and dermcidins. These 3 classes of peptides have been shown to act as antimicrobials by directly inhibiting pathogen growth as well as potentiating other branches of the innate, humoral, and cell-mediated immune system. Here, we review the antimicrobial peptides with an emphasis on their role in the cutaneous immune response. We present an overview of defensin, cathelicidin, and dermcidin physiology, elucidating their various functions. In addition, we delve into the role of these peptides in specific dermatologic conditions including wound healing, atopy, and microbial infection. Finally, we discuss the future of antimicrobial peptide research including therapeutic options.
{"title":"Antimicrobial Peptides: Effectors of Innate Immunity in the Skin","authors":"Orr Barak PhD (Medical Student) , James R. Treat MD (Resident) , William D. James MD (Paul R. Gross Professor of Dermatology; Vice Chairman and Residency Program Director)","doi":"10.1016/j.yadr.2005.07.001","DOIUrl":"10.1016/j.yadr.2005.07.001","url":null,"abstract":"<div><p><span><span>The ability of the cutaneous barrier to help defend the body against pathogens relies on both acquired and innate immune responses. Recently, a large body of research has suggested that a critical component of the innate immune response in the skin is 3 antimicrobial peptides: the </span>cathelicidins, defensins, and </span>dermcidins<span><span>. These 3 classes of peptides have been shown to act as antimicrobials by directly inhibiting pathogen growth as well as potentiating other branches of the innate, humoral, and cell-mediated immune system. Here, we review the antimicrobial peptides with an emphasis on their role in the cutaneous immune response. We present an overview of defensin, cathelicidin, and dermcidin physiology, elucidating their various functions. In addition, we delve into the role of these peptides in specific dermatologic conditions including wound healing, </span>atopy, and microbial infection. Finally, we discuss the future of antimicrobial peptide research including therapeutic options.</span></p></div>","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"21 ","pages":"Pages 357-374"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2005.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25746909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1016/j.yadr.2005.06.006
Nathaniel J. Jellinek MD (Assistant Professor)
{"title":"Primary Malignant Tumors of the Nail Unit","authors":"Nathaniel J. Jellinek MD (Assistant Professor)","doi":"10.1016/j.yadr.2005.06.006","DOIUrl":"10.1016/j.yadr.2005.06.006","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"21 ","pages":"Pages 33-64"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2005.06.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25747832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1016/j.yadr.2005.05.001
Albert C. Yan MD , Kara N. Smolinski MD, PhD
{"title":"Melanocytic Nevi: Challenging Clinical Situations in Pediatric Dermatology","authors":"Albert C. Yan MD , Kara N. Smolinski MD, PhD","doi":"10.1016/j.yadr.2005.05.001","DOIUrl":"10.1016/j.yadr.2005.05.001","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"21 ","pages":"Pages 65-80"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2005.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25747834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1016/j.yadr.2005.06.002
Lydia R. Essary MD (Clinical Assistant Professor of Dermatology) , Mai P. Hoang MD (Assistant Professor of Pathology) , K. Robin Carder MD (Assistant Professor of Dermatology and Pediatrics)
{"title":"Practical Review and Recent Developments in Pediatric Dermatopathology","authors":"Lydia R. Essary MD (Clinical Assistant Professor of Dermatology) , Mai P. Hoang MD (Assistant Professor of Pathology) , K. Robin Carder MD (Assistant Professor of Dermatology and Pediatrics)","doi":"10.1016/j.yadr.2005.06.002","DOIUrl":"10.1016/j.yadr.2005.06.002","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"21 ","pages":"Pages 193-215"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.yadr.2005.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25747839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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