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Multidisciplinary approach to management of a hereditary neurodegenerative disorder: Huntington disease. 多学科方法管理遗传性神经退行性疾病:亨廷顿病。
Pub Date : 1997-12-01
M L Klimek, G Rohs, L Young, O Suchowersky, M Trew

Huntington Disease is a well known autosomal dominant inherited disease resulting in emotional problems, abnormalities of movement, and eventually dementia. It stands out as one of the most devastating illnesses, not only for its neurodegenerative progression but also for its impact on families. Care often becomes fragmented due to the person's response to symptoms and/or family breakdown. The successful interaction of health care disciplines working with Huntington Disease in our centers, namely, the family physicians, nursing, Genetics, Neurology, Psychiatry, Social Work, and Long Term Care has resulted in a comprehensive program of care for our patients and their families. This article will describe the history, structure and interaction of the multidisciplinary group. It will describe the difficulties we have overcome and offer suggestions for the implementation of similar programs for the care of people with other disorders.

亨廷顿病是一种众所周知的常染色体显性遗传疾病,会导致情绪问题、运动异常,最终导致痴呆。它是最具破坏性的疾病之一,不仅因为它的神经退行性进展,而且因为它对家庭的影响。由于患者对症状的反应和/或家庭破裂,护理往往变得支离破碎。在我们的中心,与亨廷顿病有关的卫生保健学科,即家庭医生、护理、遗传学、神经病学、精神病学、社会工作和长期护理的成功互动,为我们的患者及其家属提供了一个全面的护理计划。本文将描述多学科小组的历史、结构和相互作用。它将描述我们所克服的困难,并为实施照顾其他疾病患者的类似方案提供建议。
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引用次数: 0
A Multiple Sclerosis (MS) Center Injection Training Program. 多发性硬化症(MS)中心注射培训项目。
Pub Date : 1997-12-01
D C Pfohl

Injectable treatments for Multiple Sclerosis inspire hope and challenges. Abilities, anxiety levels and acceptance of treatment modalities vary so a creative program and comprehensive care plan combined to meet individual needs. A flexible, two session program developed at the University of Pennsylvania MS Center includes planning, practice, and even "homework" before the initiation of drug therapy. Hints are given to manage anticipated side effects and written instructions supplement product literature. Training focuses on subcutaneous or intramuscular injection technique. Since IM injections require special skills, those prescribed Avonex (beta Interferon la) are given "anatomy lessons"; they ease tension and are fun. Learning is informal, stories are shared and expectations discussed. The patient is encouraged to maintain an informed, active role in his care, adopt a wellness lifestyle and participate fully in goals of treatment. Physical, psychological and cognitive capabilities are assessed. Safety, compliance, and relationship issues are evaluated. Rapport developed during training goes far to promote adherence to therapy, minimize lifestyle disruption and preserve an acceptable quality of life. The nurse as liaison to other professionals, particularly the prescribing physician, facilitates innovative management of treatment issues. Moving patients and carepartners toward self responsibility, informed choices and competent administration of treatments benefits all. New models of care develop and by empowering others, we empower ourselves.

注射治疗多发性硬化症激发了希望和挑战。能力、焦虑程度和对治疗方式的接受程度各不相同,因此一个创造性的项目和综合护理计划相结合,以满足个人需求。宾夕法尼亚大学多发性硬化症中心(University of Pennsylvania MS Center)开发了一个灵活的两期项目,包括药物治疗开始前的计划、练习,甚至“家庭作业”。提示管理预期的副作用和书面说明补充产品说明书。训练的重点是皮下或肌肉注射技术。由于注射内源性干扰素需要特殊的技术,那些开了Avonex (β干扰素la)的人要上“解剖课”;它们能缓解紧张,而且很有趣。学习是非正式的,故事是分享的,期望是讨论的。鼓励患者在他的护理中保持知情,积极的作用,采用健康的生活方式,并充分参与治疗目标。评估身体、心理和认知能力。评估安全性、依从性和关系问题。培训期间建立的融洽关系有助于促进对治疗的坚持,最大限度地减少对生活方式的干扰,并保持可接受的生活质量。护士作为联络其他专业人员,特别是开处方的医生,促进创新管理的治疗问题。使患者和护理伙伴朝着自我负责、知情选择和有效管理治疗的方向发展,对所有人都有益。新的护理模式不断发展,通过赋予他人权力,我们也赋予了自己权力。
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引用次数: 0
On matters not measured. A condensed version of the Mary Glover Lecture. 在无法衡量的事情上。玛丽·格洛弗讲座的浓缩版。
Pub Date : 1997-12-01
K M Buchanan
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引用次数: 0
Injury prevention programs: do they really make a difference? 伤害预防项目:它们真的有作用吗?
Pub Date : 1997-09-01
P Warnell

Brain and spinal cord injuries are a leading cause of death and disability for the youth of Canada (Damba et al, 1996). The costs of these injuries to the individual, the family, and society at large are immense. Most of these injuries are preventable (Tator et al, 1993). Over the last decade, a number of injury prevention programs have been developed to address the high incidence of traumatic central nervous system (CNS) injuries in young people. However, what remains unclear is how effective these programs are in terms of altering risk-taking behaviours. The following paper/presentation will highlight three injury prevention programs currently offered in the Toronto area: The Party Program. The Heroes Program, and The Think First Program. Each program will be outlined in terms of historical development and infrastructure, content, setting, format, and intended audience. In addition, each program will be evaluated based on criteria established by the author. Measurement of outcomes will also be addressed.

脑和脊髓损伤是加拿大青年死亡和残疾的主要原因(Damba等人,1996年)。这些伤害对个人、家庭和整个社会的代价是巨大的。这些伤害大多是可以预防的(Tator等人,1993年)。在过去的十年中,许多伤害预防计划已经制定,以解决年轻人创伤性中枢神经系统(CNS)损伤的高发。然而,目前尚不清楚的是,这些项目在改变冒险行为方面的效果如何。下面的论文/报告将重点介绍目前在多伦多地区提供的三个伤害预防项目:英雄计划和思想第一计划。每个项目将在历史发展和基础设施、内容、设置、形式和目标受众方面进行概述。此外,每个项目将根据作者制定的标准进行评估。还将讨论成果的衡量问题。
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引用次数: 0
Bridging the neurosciences. 连接神经科学。
Pub Date : 1997-09-01
W Morrison
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引用次数: 0
Children's health resource centre. 儿童健康资源中心。
Pub Date : 1997-09-01
R Kohut

The Children's Health Resource Centre was created to give children, youth and parents access to information concerning the health issues of children. As humans, whether we are children or adults, have a tendency to deal with situations better if we feel that we have some control. Knowledge empowers us-gives us that control. It enhances our ability to cope and frequently improves our recovery as well as our recovery rate. The Resource Centre is there to supply that knowledge--to become a Provincial Inquiry line for children's health. This paper will encompass the why, how, when, response, effect and future plans of the Children's Health Resource Centre.

儿童健康资源中心的设立是为了使儿童、青年和家长能够获得有关儿童健康问题的信息。作为人类,无论我们是孩子还是成年人,如果我们觉得自己有一定的控制力,就会倾向于更好地处理情况。知识赋予我们力量——给予我们控制。它可以增强我们的应对能力,并经常提高我们的恢复能力和恢复速度。资源中心在那里提供这方面的知识————成为省级儿童健康咨询热线。本文将包括儿童健康资源中心的原因、方式、时间、反应、效果和未来计划。
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引用次数: 0
The "nest"--neurological environment for safe therapeutics. “巢穴”——用于安全治疗的神经学环境。
Pub Date : 1997-09-01
B Barham, J Bartlett

How to manage neurologically impaired patients is a challenge we all face. Lions Gate Hospital in North Vancouver, B.C. successfully developed a padded environment for confused, restless, and agitated patients. The following article describes how patients are managed without restraints in a safe environment.

如何管理神经损伤患者是我们所有人都面临的挑战。不列颠哥伦比亚省北温哥华的狮门医院成功地为困惑、不安和激动的病人开发了一种软垫环境。下面的文章描述了如何在安全的环境中不受约束地管理患者。
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引用次数: 0
Protocol for intervention and treatment of alcohol withdrawal. 酒精戒断干预和治疗方案。
Pub Date : 1997-09-01
W Sander

The incidence of alcohol dependence/abuse in patients of a general health care facility is 35-50%. The diagnosis and treatment of patients experiencing or at risk of alcohol withdrawal is problematic. The admitting diagnosis is usually another medical condition, illness or injury. Signs and symptoms of alcohol withdrawal is complicated by pre-existing conditions. In an attempt to improve the quality of care, decrease the length of stay of these patients, and decrease demands on nursing staff, a protocol for intervention and treatment of alcohol withdrawal was developed on the orthopedic ward of Royal University Hospital. The protocol enables each nurse to assess. Intervene and initiate the proper referrals. The recognized tool of assessment used to identify at risk patients is the CAGE questionnaire. The Clinical Institute WithDrawal Assessment for Alcohol scale is used to determine when it is appropriate to use Benzodiazepines. General nursing considerations are addressed through a pre-printed care plan. Nurses refer to social work, Alcoholics Anonymous and make use of available resource material. The protocol enables nurses to provide safe and effective care with few associated costs. Except for mass immunization, there is no other single intervention in health care that has the same far reaching consequences (Sullivan, 1995).

在普通卫生保健机构的病人中,酒精依赖/滥用的发生率为35-50%。正在经历或有戒酒风险的患者的诊断和治疗是有问题的。入院诊断通常是另一种医疗状况、疾病或伤害。酒精戒断的症状和体征因先前存在的疾病而变得复杂。为了提高护理质量,减少这些病人的住院时间,减少对护理人员的需求,在皇家大学医院骨科病房制定了一项干预和治疗戒酒的协议。该方案使每个护士都能进行评估。干预和启动适当的转介。用于识别高危患者的公认评估工具是CAGE问卷。临床研究所酒精戒断评估量表用于确定何时适合使用苯二氮卓类药物。一般护理注意事项通过预先打印的护理计划解决。护士参考社会工作,匿名戒酒会,并利用可利用的资源材料。该方案使护士能够以很少的相关费用提供安全有效的护理。除大规模免疫接种外,在卫生保健方面没有其他单一干预措施具有同样深远的影响(Sullivan, 1995年)。
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引用次数: 0
Surgical interventions in the treatment of Parkinson's disease (PD) and essential tremor (ET): medial pallidotomy in PD and chronic deep brain stimulation (DBS) in PD and ET. 手术干预治疗帕金森病(PD)和特发性震颤(ET):内侧苍白术治疗PD和慢性深部脑刺激(DBS)治疗PD和ET。
Pub Date : 1997-06-01
J Duff, E Sime

Surgical treatments for PD and ET are promising. Medial Pallidotomy, the surgical lesioning of the pallidum, often improves symptoms of long-standing PD. We enrolled twenty-seven late stage PD patients for unilateral medial pallidotomy who were then assessed by the Core Assessment Program for Intracranial Transplantation (CAPIT) protocol. One year after surgery persistent improvement was seen contralateral to the lesion in the following features: drug-induced dyskinesias (92%), akinesia (38%), rigidity (51%), and tremor (42%). Complications included transient dysarthria (7 patients), facial weakness (9 patients), limb weakness (1 patient), swallowing problems (4 patients) and intracerebral haemorrhage (1 patient). Thalamic DBS may improve tremor in PD and ET patients. Therefore, we enrolled fifteen patients (9 PD and 6 ET patients) with disabling tremor, unresponsive to medication. They were assessed by the United Parkinson's Disease Rating Scale (UPDRS) and the Tremor Rating Scale (for PD and ET patients, respectively). Three months after surgery, limb tremor contralateral to stimulation improved by 71% in PD patients and 76% in ET patients. Complications included transient paresthesias (all), confusional state (1 patient) and intracerebral bleed (1 patient). Unilateral medial pallidotomy safely improves some Parkinsonian symptoms contralateral to the lesion. Thalamic DBS may effectively and safely improve contralateral limb tremor in PD and ET.

手术治疗PD和ET是有希望的。内侧苍白球切开术,手术切除苍白球,常能改善长期帕金森病的症状。我们招募了27例晚期PD患者进行单侧内侧苍白球切开术,然后通过颅内移植核心评估计划(CAPIT)方案对其进行评估。术后一年病灶对侧持续改善如下特征:药物性运动障碍(92%)、运动障碍(38%)、强直(51%)和震颤(42%)。并发症包括短暂性构音障碍(7例)、面部无力(9例)、肢体无力(1例)、吞咽困难(4例)和脑出血(1例)。丘脑DBS可能改善PD和ET患者的震颤。因此,我们招募了15例对药物无反应的致残性震颤患者(9例PD和6例ET)。他们通过联合帕金森病评定量表(UPDRS)和震颤评定量表(分别用于PD和ET患者)进行评估。手术后3个月,PD患者对侧刺激的肢体震颤改善了71%,ET患者改善了76%。并发症包括短暂性感觉异常(全部)、精神错乱(1例)和脑出血(1例)。单侧内侧苍白球切开术可安全改善病变对侧部分帕金森症状。丘脑DBS可有效、安全地改善PD和ET对侧肢体震颤。
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引用次数: 0
The treatment of chronic pain by epidural spinal cord stimulation--a 15 year follow up; present status. 硬膜外脊髓刺激治疗慢性疼痛——15年随访现状。
Pub Date : 1997-06-01
P Lang

Pain is necessary for survival but chronic pain is disabling and causes significant health and economic problems. This study provides an understanding of the future for spinal cord stimulation. Stimulation by means of chronically implanted electrodes, was carried out in 200 patients with pain of varied benign organic etiology. In 177 of them, pain was confined to the failed back syndrome. Most patients were referred by a Pain Management Service. 226 epidural implants were used: 80 unipolar, 59 Resume, 12 bipolar, and 75 quadripolar. Patients were followed for periods of 6 months to 12 years, with a mean follow-up of 44 months. 84 patients (42%) were able to control their pain by stimulation alone, 22 patients (11%) needed occasional analgesic supplements along with their stimulation program. Pain secondary to failed back syndrome, multiple sclerosis, peripheral vascular disease, sympathetic dystrophy and diabetic neuropathy responded favorably. Pain due to cauda equina injury, paraplegic pain and phantom limb pain responded poorly. Complications included wound infection, displaced or fracture electrode, and fibrosis at the stimulating tip. Spinal cord stimulation has proven to be effective in the treatment of chronic benign pain.

疼痛是生存所必需的,但慢性疼痛是致残的,并导致严重的健康和经济问题。这项研究为脊髓刺激的未来提供了一个认识。通过长期植入电极的刺激,对200例不同良性器质性病因的疼痛患者进行了研究。其中177人的疼痛局限于背部衰竭综合症。大多数患者由疼痛管理服务中心转诊。226例使用硬膜外植入物:80例单极,59例恢复,12例双极,75例四极。患者随访时间为6个月至12年,平均随访时间为44个月。84例患者(42%)能够通过单独的刺激控制疼痛,22例患者(11%)需要在刺激方案中偶尔补充镇痛药。继发于背部衰竭综合征、多发性硬化症、周围血管疾病、交感神经营养不良和糖尿病神经病变的疼痛反应良好。马尾损伤引起的疼痛、截瘫痛和幻肢痛反应较差。并发症包括伤口感染、电极移位或断裂、刺激尖端纤维化。脊髓刺激已被证明是有效的治疗慢性良性疼痛。
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引用次数: 0
期刊
Axone (Dartmouth, N.S.)
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