Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)最新文献

The photodynamic effect may damage the choroid-retina in AMD, which involve to oxygen producing the superoxide free radical. The enzymatic and non-enzymatic defence systems would appear the capacity to scavenge the toxication in choroid and retina. We observed the superoxide dismutase and catalase decreased as well as the decrease of serum zinc in AMD patients than in the controls (p > 0.01). The results showed the protective capacity decreased by the enzymatic and non-enzymic defense systems in some AMD patients. It may be one of the important roles in the pathogenesis of AMD.

Colloid cysts of the third ventricle are rare intracranial lesions which comprise 0.5 to 1% of all intracranial tumors. We describe a patient with a third ventricle colloid cyst who presented with non specific visual deterioration.

We examined 25 patients affected from Cooley's disease and five by beta-thalassemia intermedia. The mean age was 15 +/- 6.3 years. Fifteen patients, (18 years or older) three of them affected by beta-thalassemia intermedia, presented ocular abnormalities. So it was impossible to establish a correlation between laboratory data and ocular damages; their observation, with reference to untreated beta-thalassemia subjects, suggested that ocular abnormalities cannot be only attributed to desferrioxamine treatment.

Malignant fibrous histiocytomas are common sarcomas of later life. They arise most commonly in the lower extremities and, only rarely, in the head and neck. Fibrous histiocytomas, mostly benign, have been reported in the orbit and conjunctiva, but only three benign lesions have been described in the eyelids. I present a case of malignant fibrous histiocytoma of the eyelid which recurred locally, but has shown no evidence of metastases.

Osteoblastoma is a rare bone tumor involving spine, long bones and infrequently skull, especially with sinus localization. The orbital localization of the neoplasia may cause axial or paraxial exophthalmus, vertical diplopia, pulsatile orbital pain, soft tissue swelling with skin erythema. In addition the osteoblastoma may cause an optic nerve compression, with optic disc edema up to optic nerve atrophy. We describe a case of giant benign osteoblastoma with frontal occurrence and orbital involvement with optic nerve compression. Surgery was performed in order to obtain the partial ablation of the neoplasia. After a 4-year follow-up there was no evidence of recurrence.

A 35-year-old Japanese woman with nephrotic syndrome due to mesangial proliferative glomerulonephritis was treated with steroid hormone for 5 years and suddenly developed uveitis in the left eye. She had many cells in the anterior chamber, fine granular keratitic precipitates on the posterior surface of the cornea and retinal edema around the optic disc. Diabetes mellitus had been diagnosed, but it was considered to be steroid diabetes mellitus. This patient showed depressed spontaneous blastogenesis. Since nephrotic syndrome is occasionally associated with an immune-mediated process, uveitis in this case might be related to an immunity disorder.

We report a case of a 46-year-old man who developed mature cataract in one eye and nearly mature cataract in his other eye over a 14-month period. No genetic, traumatic, or toxic etiology or intraocular pathology or history of irradiation were present. The patient had intentionally been drinking 15 liters of water a day for 11 months, up until 3 months prior to his admission, and 5 liters a day thereafter, until his admission. During his hospitalization he was found to suffer from insulin-dependent diabetes mellitus. The rest of his medical work-up was found to be normal. We suggest that the huge water overload put on his lens played a role in the premature and rapid cataract formation.

Fat absorption was studied in 24 patients with clinically definite multiple sclerosis and in 36 healthy control subjects. Beta-carotene and vitamin A in their plasma were also measured. This double-blind and randomized study showed no differences between these two populations with regard to the three parameters. We did not find evidence for fat malabsorption in multiple sclerosis.