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Mastopexy With Inferior-septal Pedicle and Dermal Fixation: A Modification to Improve Aesthetic Stability. 下间隔蒂和真皮固定乳房固定术:一种改善美学稳定性的改良方法。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-20 DOI: 10.1093/asj/sjag010
Maksim Barsakov, Natalia Korableva

Background: Breast ptosis remains challenging, particularly when excess skin and parenchyma are pronounced. Inferior-pedicle techniques may be prone to recurrent ptosis with lower-pole elongation and loss of upper-pole projection.

Objectives: To describe and evaluate a mastopexy technique using an inferior-septal pedicle with dermal-muscular fixation designed to enhance long-term stability in severe ptosis (Regnault grade III).

Methods: Single-surgeon, single-center consecutive case series (level IV). One hundred sixteen women with grade III ptosis underwent surgery from January 2016 to June 2023. The technique uses an inferior-septal dermoglandular pedicle with dermal fixation to the pectoralis major. Outcomes were assessed via standardized examinations, photography, and the BREAST-Q Reduction/Mastopexy module at 3, 6, and 12 months.

Results: A total of 116 patients were analyzed (median follow-up, 12 months). Mean SN-N distance decreased from 36.3 to 22.0 cm, and N-IMF from 14.5 to 8.0 cm at 12 months. BREAST-Q scores at 12 months demonstrated high satisfaction (mean ≥80/100). No NAC-related vascular events, infections, or hematomas occurred (0%). Wound-healing disturbances were noted in 16/232 breasts (6.9%). Revisions occurred in 13/116 patients (11.2%), mainly scar adjustments; secondary ptosis correction was required in 5/116 (4.3%). No cases of persistent nipple sensory loss were observed.

Conclusions: The proposed mastopexy technique with inferior-septal pedicle provides effective correction of severe ptosis with good upper-pole fullness and stable long-term breast shape, while preserving NAC perfusion, innervation, and potential lactational function.

背景:乳房下垂仍然具有挑战性,特别是当多余的皮肤和实质是明显的。下椎弓根技术可能容易导致复发性上睑下垂,并伴有下极延伸和上极投射丧失。目的:描述和评估一种使用下间隔蒂真皮-肌肉固定的乳房固定术,旨在提高重度上睑下垂的长期稳定性(Regnault III级)。方法:单外科医生、单中心连续病例系列(IV级)。2016年1月至2023年6月,116名III级上睑下垂女性接受了手术。该技术采用下隔皮腺蒂与胸大肌真皮固定。在3、6和12个月时通过标准化检查、摄影和BREAST-Q复位/乳房固定术模块评估结果。结果:共分析116例患者(中位随访12个月)。12个月平均SN-N距离从36.3 cm下降到22.0 cm, N-IMF从14.5 cm下降到8.0 cm。12个月时BREAST-Q评分显示满意度高(平均≥80/100)。无nac相关血管事件、感染或血肿发生(0%)。232例乳房中有16例(6.9%)存在伤口愈合障碍。116例患者中有13例(11.2%)进行了修复,主要是疤痕调整;5/116(4.3%)需要二次上睑下垂矫正。无持续性乳头感觉丧失病例。结论:所提出的下间隔蒂乳房固定术在保留NAC灌注、神经支配和潜在泌乳功能的同时,能有效矫正重度上睑下垂,上极饱满,长期稳定乳房形状。
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引用次数: 0
Internal Nasal Dilators After Septorhinoplasty: A Randomized Controlled Trial of Functional and Aesthetic Outcomes. 鼻中隔成形术后的内鼻扩张器:一项功能和美学结果的随机对照试验。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-19 DOI: 10.1093/asj/sjag007
Raisa Chowdhury, Nisreen Al-Musaileem, Islam Alzayadneh, Aseel Doubi, Karanvir S Raman, Philip Solomon, Richard Rival

Background: Postoperative nasal obstruction and asymmetry can compromise satisfaction after rhinoplasty. Internal nasal dilators (INDs) may support early healing by maintaining valve patency and symmetry, but their postoperative efficacy has not been systematically evaluated.

Objectives: To determine whether IND use after septorhinoplasty improves functional, aesthetic, and symmetry outcomes compared with standard care.

Methods: In this single-center, randomized, single-blinded trial, 128 adults undergoing primary septorhinoplasty were allocated (1:1) to IND plus standard care or standard care alone. Assessments were performed at baseline, 3 months, and 12 months using the validated Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) and a nostril-symmetry item (0 = perfect, 4 = very asymmetrical). The primary outcome was patient-reported nostril symmetry; secondary outcomes included functional and aesthetic SCHNOS scores, comfort, and adverse events.

Results: Baseline characteristics were comparable. Nostril symmetry scores favored the IND group at 3 months (0.78 ± 0.92 vs 1.42 ± 1.09; p = .001) and 12 months (0.46 ± 0.71 vs 1.40 ± 1.20; p < .001). Functional SCHNOS improved in both groups, with a slightly greater gain in the IND group at 12 months (+10.2 ± 4.1 vs +7.9 ± 4.4; p = .048). Aesthetic SCHNOS scores improved similarly across groups (p = .73). Device comfort was high (VAS 8.1 ± 1.4/10), and no device-related complications occurred.

Conclusions: Internal nasal dilators improved postoperative nostril symmetry and maintained favorable functional and aesthetic outcomes without added risk or discomfort. These findings support the adjunctive use of INDs to enhance symmetry and patient satisfaction after rhinoplasty.

背景:术后鼻塞和不对称会影响鼻整形术后的满意度。内鼻扩张器(INDs)可以通过维持瓣膜的开放和对称来支持早期愈合,但其术后疗效尚未得到系统的评估。目的:确定与标准护理相比,鼻中隔成形术后使用IND是否能改善功能、美学和对称性。方法:在这项单中心、随机、单盲试验中,128名接受初级鼻中隔成形术的成年人(1:1)被分配到IND加标准治疗或单独标准治疗组。在基线、3个月和12个月进行评估,使用经过验证的标准化美容和健康鼻部结果调查(SCHNOS)和鼻孔对称项目(0 =完美,4 =非常不对称)。主要结局是患者报告的鼻孔对称;次要结局包括功能和美学SCHNOS评分、舒适度和不良事件。结果:基线特征可比较。鼻孔对称评分在3个月(0.78±0.92 vs 1.42±1.09,p = 0.001)和12个月(0.46±0.71 vs 1.40±1.20,p < 0.001)时优于IND组。两组的功能性SCHNOS均有改善,IND组在12个月时的增加略大(+10.2±4.1 vs +7.9±4.4;p = 0.048)。美学SCHNOS评分在各组间的改善相似(p = 0.73)。器械舒适度高(VAS 8.1±1.4/10),无器械相关并发症发生。结论:内扩鼻器改善了术后鼻孔的对称性,并保持了良好的功能和美观效果,没有增加风险或不适。这些发现支持辅助使用INDs来增强鼻整形术后的对称性和患者满意度。
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引用次数: 0
A Systematic Review of Medicolegal Social Media Related Issues in Plastic Surgery. 整形外科中与社会媒体相关的医学法律问题的系统综述。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-19 DOI: 10.1093/asj/sjag008
Albert Brotgandel, Sarah Moffitt, Carson Bair, Claudia Cruz, Joshua Scarcella, Meredith Moore, Paul Smith

Social media has become a powerful tool in plastic surgery, offering opportunities to attract patients and share content. However, its use raises medicolegal challenges, including privacy, defamation, and professional boundaries. The impact of social media on lawsuits involving plastic surgeons remains underexplored. A systematic review of publicly available legal cases was conducted using WestLaw and Nexis Uni databases, covering January 2007 - January 2024. 135 unique cases were screened by three independent reviewers. Inclusion required involvement of social media and plastic surgeons or practices. Twenty-seven cases met criteria and were analyzed for plaintiff/defendant status, cause of action, use of anti-SLAPP statutes, and case outcomes. Of the 27 included cases, 17 were filed by plastic surgeons, seven by patients, two by practices, and one by a non-patient. Defamation was the most common claim (15/27). Plastic surgeons and patients were equally represented as defendants. Only three defamation cases resulted in court rulings favoring the plaintiff, and one case was settled in arbitration. Additional claims included invasion of privacy, copyright infringement, trademark violation, and misappropriation of likeness. Cases highlighted risks associated with improper handling of patient photographs and employee-managed accounts. Plastic surgeons face growing medicolegal exposure related to social media. Defamation lawsuits against patients rarely succeed. Surgeons should avoid litigation as a primary strategy and instead mitigate risk through clear policies, professional conduct, and strong physician-patient communication. Proactive reputation management and adherence to ethical standards remain the most effective tools to reduce litigation in the social media era.

社交媒体已经成为整形手术的有力工具,为吸引患者和分享内容提供了机会。然而,它的使用引发了医学上的挑战,包括隐私、诽谤和专业界限。社交媒体对涉及整形外科医生的诉讼的影响仍未得到充分研究。利用WestLaw和Nexis Uni数据库对2007年1月至2024年1月期间的公开法律案件进行了系统审查。135个独特的案例由三名独立审稿人筛选。纳入需要参与社交媒体和整形外科医生或实践。27个案例符合标准,并分析了原告/被告地位、诉讼原因、反slapp法规的使用和案件结果。在27起案件中,17起是整形外科医生提出的,7起是患者提出的,2起是诊所提出的,1起是非患者提出的。诽谤是最常见的索赔(15/27)。作为被告,整形外科医生和患者的代表是平等的。只有三起诽谤案件的法院判决有利于原告,还有一起案件通过仲裁解决。其他索赔包括侵犯隐私、侵犯版权、侵犯商标和盗用肖像。案例突出了与患者照片和员工管理账户处理不当相关的风险。整形外科医生面临着与社交媒体相关的越来越多的医学法律风险。针对患者的诽谤诉讼很少能成功。外科医生应将避免诉讼作为主要策略,而应通过明确的政策、专业行为和强有力的医患沟通来降低风险。在社交媒体时代,积极的声誉管理和遵守道德标准仍然是减少诉讼的最有效工具。
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引用次数: 0
Axillary Approach Non-Skin-Excisional Mastectomy Without Endoscopic Assistance in Chest Masculinization Surgery. 腋窝入路非皮肤切除乳房切除术无内窥镜辅助胸部男性化手术。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-19 DOI: 10.1093/asj/sjag009
Xin Tang

Background: For gender-affirming mastectomy in patients with gender dysphoria and small/non-ptotic breasts, traditional periareolar techniques carry risks of visible scar complications. A scar-minimizing alternative is needed.

Objectives: To evaluate the outcomes of a novel non-endoscopic axillary approach mastectomy, aiming to eliminate areolar scars or diminish circumareolar incision while assessing safety and patient satisfaction.

Methods: This study included patients classified with Fisher 1, 2a, and a portion of 2b patients. Mastectomy was performed via an axillary incision without endoscopic assistance. Outcomes were evaluated through complication rates and patient-reported outcomes using the BODY-Q questionnaire (score 0-100).

Results: From December 2020 to August 2024, 48 patients (average age 33.65) underwent the procedure. The average operative time was 167.1 minutes. The overall complication rate was 45.8% (22/48), predominantly minor, reversible nipple-areola superficial skin necrosis (20.8%). Severe complications were rare: total NAC necrosis 2.0% (1/48) and acute hematoma 2.0% (1/48). Patient satisfaction on the BODY-Q scale was statistically very high.

Conclusions: This axillary approach for mastectomy successfully prioritizes minimal scarring, a key aesthetic concern particularly for East Asian patients. In a carefully selected cohort, it achieves high patient satisfaction with a low rate of severe complications, offering a valuable surgical alternative.

背景:对于性别焦虑和小/非下垂乳房患者的性别确认乳房切除术,传统的乳晕周围技术存在可见疤痕并发症的风险。需要一种最小化疤痕的替代方案。目的:评估一种新型的非内窥镜腋窝入路乳房切除术的结果,旨在消除乳晕疤痕或减少乳晕周围切口,同时评估安全性和患者满意度。方法:本研究纳入Fisher 1、2a和部分2b患者。乳房切除术通过腋窝切口进行,没有内窥镜辅助。通过使用BODY-Q问卷(评分0-100)评估并发症发生率和患者报告的结果。结果:从2020年12月到2024年8月,48例患者(平均年龄33.65岁)接受了手术。平均手术时间167.1分钟。总并发症发生率为45.8%(22/48),以轻微、可逆性乳头乳晕浅表皮肤坏死为主(20.8%)。严重并发症罕见:全NAC坏死2.0%(1/48),急性血肿2.0%(1/48)。患者对BODY-Q量表的满意度在统计上非常高。结论:这种腋窝入路乳房切除术成功地优先考虑了最小的疤痕,这是一个关键的美学问题,特别是对东亚患者。在一个精心挑选的队列中,它实现了高患者满意度和低严重并发症率,提供了一个有价值的手术选择。
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引用次数: 0
Botulinum Toxin Type A in the Treatment of Primary Axillary Hyperhidrosis:A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety in Chinese Patients. A型肉毒毒素治疗原发性腋毛多汗症:一项3期、多中心、随机、双盲、安慰剂对照的疗效和安全性研究。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-19 DOI: 10.1093/asj/sjaf260
Yiming Li, Baogang Sun, Jianyun Lu, Wei Lai, Huiping Wang, Qiuning Sun, Baoxi Wang, Yanyan Feng, Junfeng He, Yubao Huang, Yunkai Yang, Chengjun Zhang, Li Li

Background: The efficacy and safety of botulinum toxin type A (BoNTA) treatment for primary axillary hyperhidrosis (PAH) have not been explored in the Chinese population.

Objectives: The objective was to evaluate efficacy and safety of 1 intradermal BoNTA injection in Chinese PAH cases.

Methods: This was a Phase 3, multicenter, randomized, double-blind, placebo-controlled study. Patients were randomized to an experimental group or the control group at a ratio of 3:1 and received either BoNTA or a placebo once. The primary efficacy endpoint was the proportion of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment compared to baseline. The key secondary efficacy endpoints were the percentage changes in axillary sweat weight at Weeks 1, 4, 8, and 16 posttreatment.

Results: A total of 344 patients were randomized to the experimental group (n = 258) or the control group (n = 86). The proportions of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment were 83.72% (216/258) in the experimental group and 55.81% (48/86) in the control group, respectively. The between-group difference was 27.91% (P < .001). BoNTA treatment yielded a significant reduction in axillary sweat weight, hyperhidrotic area, hyperhidrosis disease severity scale (HDSS) scores, and grade of bromhidrosis. The patients in the experimental group reported significantly higher satisfaction scores than those in the control group. BoNTA treatment was well tolerated. Neither group experienced suspected unexpected serious adverse reactions, or adverse events or adverse drug reactions leading to withdrawal or death.

Conclusions: One intradermal 50-U BoNTA treatment led to a significant reduction in axillary sweat weight, axillary hyperhidrotic area, HDSS scores, and axillary bromhidrosis grades in Chinese PAH patients. The therapeutic effect was maintained for 16 weeks posttreatment, with a favorable safety profile.

Level of evidence: 1 (therapeutic):

背景:A型肉毒毒素(BoNTA)治疗原发性腋下多汗症(PAH)的疗效和安全性尚未在中国人群中进行探讨。目的:评价1种皮内注射BoNTA治疗中国PAH病例的疗效和安全性。方法:这是一项3期、多中心、随机、双盲、安慰剂对照研究。患者按3:1的比例随机分为实验组和对照组,接受BoNTA或安慰剂治疗一次。主要疗效终点是与基线相比,治疗后第4周腋窝汗液重量减少超过50%的患者比例。关键的次要疗效终点是治疗后第1、4、8和16周时腋窝汗液重量的百分比变化。结果:344例患者随机分为实验组(n = 258)和对照组(n = 86)。治疗后第4周腋窝汗液重量减少50%以上的患者比例,实验组为83.72%(216/258),对照组为55.81%(48/86)。组间差异为27.91% (P < 0.001)。BoNTA治疗显著降低腋窝汗液重量、多汗面积、多汗疾病严重程度量表(HDSS)评分和腋臭等级。实验组患者满意度得分明显高于对照组。BoNTA治疗耐受性良好。两组均未发生可疑的意外严重不良反应,或导致停药或死亡的不良事件或药物不良反应。结论:一种皮内50-U BoNTA治疗可显著降低中国PAH患者的腋窝汗液重量、腋窝多汗面积、HDSS评分和腋窝腋臭评分。治疗后疗效维持16周,具有良好的安全性。证据水平:1(治疗性);
{"title":"Botulinum Toxin Type A in the Treatment of Primary Axillary Hyperhidrosis:A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety in Chinese Patients.","authors":"Yiming Li, Baogang Sun, Jianyun Lu, Wei Lai, Huiping Wang, Qiuning Sun, Baoxi Wang, Yanyan Feng, Junfeng He, Yubao Huang, Yunkai Yang, Chengjun Zhang, Li Li","doi":"10.1093/asj/sjaf260","DOIUrl":"https://doi.org/10.1093/asj/sjaf260","url":null,"abstract":"<p><strong>Background: </strong>The efficacy and safety of botulinum toxin type A (BoNTA) treatment for primary axillary hyperhidrosis (PAH) have not been explored in the Chinese population.</p><p><strong>Objectives: </strong>The objective was to evaluate efficacy and safety of 1 intradermal BoNTA injection in Chinese PAH cases.</p><p><strong>Methods: </strong>This was a Phase 3, multicenter, randomized, double-blind, placebo-controlled study. Patients were randomized to an experimental group or the control group at a ratio of 3:1 and received either BoNTA or a placebo once. The primary efficacy endpoint was the proportion of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment compared to baseline. The key secondary efficacy endpoints were the percentage changes in axillary sweat weight at Weeks 1, 4, 8, and 16 posttreatment.</p><p><strong>Results: </strong>A total of 344 patients were randomized to the experimental group (n = 258) or the control group (n = 86). The proportions of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment were 83.72% (216/258) in the experimental group and 55.81% (48/86) in the control group, respectively. The between-group difference was 27.91% (P < .001). BoNTA treatment yielded a significant reduction in axillary sweat weight, hyperhidrotic area, hyperhidrosis disease severity scale (HDSS) scores, and grade of bromhidrosis. The patients in the experimental group reported significantly higher satisfaction scores than those in the control group. BoNTA treatment was well tolerated. Neither group experienced suspected unexpected serious adverse reactions, or adverse events or adverse drug reactions leading to withdrawal or death.</p><p><strong>Conclusions: </strong>One intradermal 50-U BoNTA treatment led to a significant reduction in axillary sweat weight, axillary hyperhidrotic area, HDSS scores, and axillary bromhidrosis grades in Chinese PAH patients. The therapeutic effect was maintained for 16 weeks posttreatment, with a favorable safety profile.</p><p><strong>Level of evidence: 1 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146002856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of Migraine and Sinus Headaches in Patients Undergoing Primary Rhinoplasty. 初次鼻整形患者偏头痛和鼻窦性头痛的发生率。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-16 DOI: 10.1093/asj/sjag006
Ryan Cvelbar, R'ay Fodor, Elad Fraiman, Bahman Guyuron

Background: Nearly two thirds of patients who suffer from migraine headaches (MH) have a rhinogenic trigger site. A majority of rhinoplasty patients are female, and an estimated 18% of females suffer from MH. Rhinogenic MH and sinus headaches (SH) are commonly triggered by elements which can be readily addressed during septorhinoplasty. Consequently, this surgery may present a dual opportunity to address MH/SH and cosmetic concerns simultaneously.

Objectives: This study aims to quantify the incidence of MH and SH in patients presenting for primary rhinoplasty.

Methods: A retrospective review was conducted on a consecutive sample of patients who presented for primary rhinoplasty. The senior author's 2-page preoperative questionnaire which inquires about MH and SH was used to identify patients who self-reported MH and SH. MH and SH incidences were calculated as a percentage of the total number of patient responses.

Results: A total of 190 primary rhinoplasty patients (164 females (86.32%) and 26 males (13.68%)) were included in this study. In total, 64 (33.68%) had either SH or MH. Twenty-nine patients (15.26%) had SH only, 12 (6.32%) MH only, 23 (12.11%) both MH and SH, and 35 (18.42%) had MH with or without SH.

Conclusions: MH incidence (18.42%) in this patient sample was greater than the reported global migraine rate of 14-15%. By screening for and treating rhinogenic MH and SH, surgeons can both alleviate symptoms while fulfilling aesthetic objectives.

背景:近三分之二的偏头痛(MH)患者有鼻源性触发部位。大多数隆鼻患者是女性,估计18%的女性患有鼻源性MH和鼻窦头痛(SH)通常是由鼻中隔成形术中容易解决的因素引发的。因此,该手术可能提供双重机会,同时解决MH/SH和美容问题。目的:本研究旨在量化原发性鼻整形患者MH和SH的发生率。方法:回顾性评价了一个连续的样本的患者谁提出了初级鼻整形。使用资深作者的两页术前问卷调查MH和SH,以确定自我报告MH和SH的患者。计算MH和SH发生率占患者总应答数的百分比。结果:本研究共纳入190例鼻整形患者,其中女性164例(86.32%),男性26例(13.68%)。共有64例(33.68%)患者患有SH或MH,其中单纯SH患者29例(15.26%),单纯MH患者12例(6.32%),同时MH和SH患者23例(12.11%),MH合并或不合并SH患者35例(18.42%)。结论:该患者样本中MH发病率(18.42%)高于报道的全球偏头痛发病率(14-15%)。通过筛查和治疗鼻源性MH和SH,外科医生既可以减轻症状,又可以实现美学目标。
{"title":"Frequency of Migraine and Sinus Headaches in Patients Undergoing Primary Rhinoplasty.","authors":"Ryan Cvelbar, R'ay Fodor, Elad Fraiman, Bahman Guyuron","doi":"10.1093/asj/sjag006","DOIUrl":"https://doi.org/10.1093/asj/sjag006","url":null,"abstract":"<p><strong>Background: </strong>Nearly two thirds of patients who suffer from migraine headaches (MH) have a rhinogenic trigger site. A majority of rhinoplasty patients are female, and an estimated 18% of females suffer from MH. Rhinogenic MH and sinus headaches (SH) are commonly triggered by elements which can be readily addressed during septorhinoplasty. Consequently, this surgery may present a dual opportunity to address MH/SH and cosmetic concerns simultaneously.</p><p><strong>Objectives: </strong>This study aims to quantify the incidence of MH and SH in patients presenting for primary rhinoplasty.</p><p><strong>Methods: </strong>A retrospective review was conducted on a consecutive sample of patients who presented for primary rhinoplasty. The senior author's 2-page preoperative questionnaire which inquires about MH and SH was used to identify patients who self-reported MH and SH. MH and SH incidences were calculated as a percentage of the total number of patient responses.</p><p><strong>Results: </strong>A total of 190 primary rhinoplasty patients (164 females (86.32%) and 26 males (13.68%)) were included in this study. In total, 64 (33.68%) had either SH or MH. Twenty-nine patients (15.26%) had SH only, 12 (6.32%) MH only, 23 (12.11%) both MH and SH, and 35 (18.42%) had MH with or without SH.</p><p><strong>Conclusions: </strong>MH incidence (18.42%) in this patient sample was greater than the reported global migraine rate of 14-15%. By screening for and treating rhinogenic MH and SH, surgeons can both alleviate symptoms while fulfilling aesthetic objectives.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145987926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary on: Research Requirements for Residency Applicants Need to be Reconsidered. 评论:需要重新考虑对居留申请人的研究要求。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-12 DOI: 10.1093/asj/sjag004
Andrew Y Zhang
{"title":"Commentary on: Research Requirements for Residency Applicants Need to be Reconsidered.","authors":"Andrew Y Zhang","doi":"10.1093/asj/sjag004","DOIUrl":"https://doi.org/10.1093/asj/sjag004","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and Effectiveness of a Cross-linked Hyaluronic Acid Filler in Korean Subjects for the Correction of Nasolabial Folds: A Randomized, Subject- and Evaluator-blind, Paired Study. 交联透明质酸填充剂在韩国受试者鼻唇褶皱矫正中的安全性和有效性:一项随机、受试者和评估者盲、配对研究。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-08 DOI: 10.1093/asj/sjag003
Si-Hyung Lee, Eunsoo Park, Chong Hyun Won

Background: Hyaluronic acid (HA) dermal fillers are widely used as a non-surgical treatment for facial aging, including nasolabial folds (NLFs). As demand for convenient aesthetic procedures increases, new HA products require rigorous comparison with established fillers.

Objectives: To assess the non-inferiority and safety of a new cross-linked HA filler, SkinPlus-HYAL Implant Lidocaine (test), versus RESTYLANE Lidocaine (control) for temporary correction of moderate to severe NLFs.

Methods: In this multicenter, randomized, subject- and evaluator-blinded, split-face study, 100 adults with moderate or severe NLFs received the test filler in one NLF and the control in the contralateral NLF. Efficacy was analyzed in the Full Analysis Set (N=93). The primary endpoint was the between-treatment difference in Wrinkle Severity Rating Scale (WSRS) scores at Week 24. Safety was evaluated in the Safety Set (N=100). Group differences were analyzed using a two-sample t-test.

Results: At Week 24, mean WSRS scores were 1.85±0.72 (test) and 1.84±0.68 (control). The mean difference (test - control) was 0.01±0.48, with an upper 97.5% one-sided confidence limit of 0.2136, below the prespecified non-inferiority margin of 0.29. Investigator-rated Global Aesthetic Improvement Scale (GAIS) scores at Week 24 and subject-rated GAIS scores at Week 8 favored the test filler. Local adverse event were more frequent with the test (92.00%) than the control (82.0%), but severe injection-site reactions were uncommon, and no serious adverse events occurred.

Conclusions: SkinPlus-HYAL Implant Lidocaine was non-inferior to RESTYLANE Lidocaine for correction of moderate to severe NLFs and maintained efficacy through 48 weeks. Despite a higher rate of local reactions, its overall safety profile was acceptable, supporting its use as an effective, safe option for facial aesthetic augmentation.

背景:透明质酸(HA)真皮填充剂被广泛用于面部老化的非手术治疗,包括鼻唇褶皱(nlf)。随着对方便的美容程序的需求增加,新的HA产品需要与现有的填料进行严格的比较。目的:评估一种新的交联HA填充剂SkinPlus-HYAL种植体利多卡因(试验)与RESTYLANE利多卡因(对照)用于暂时矫正中重度NLFs的非劣效性和安全性。方法:在这项多中心、随机、受试者和评估者双盲、裂面研究中,100名患有中度或重度NLFs的成年人在一侧NLFs中接受了测试填充物,而在对侧NLFs中接受了对照组。在全分析集(N=93)中分析疗效。主要终点是第24周皱纹严重性评定量表(WSRS)评分的治疗间差异。在安全集(N=100)中评估安全性。组间差异分析采用双样本t检验。结果:第24周时,患者的平均WSRS评分分别为1.85±0.72(试验组)和1.84±0.68(对照组)。平均差异(检验-对照)为0.01±0.48,单侧置信限为0.2136,上限为97.5%,低于预先设定的非劣效性边际0.29。第24周的研究者评定的全球审美改善量表(GAIS)分数和第8周的受试者评定的GAIS分数倾向于测试填充物。局部不良事件发生率(92.00%)高于对照组(82.0%),但严重注射部位反应罕见,未发生严重不良事件。结论:SkinPlus-HYAL植入体利多卡因对中重度NLFs的矫正效果不低于RESTYLANE利多卡因,且疗效维持48周。尽管局部反应率较高,但其整体安全性是可接受的,支持其作为有效,安全的面部美容选择。
{"title":"Safety and Effectiveness of a Cross-linked Hyaluronic Acid Filler in Korean Subjects for the Correction of Nasolabial Folds: A Randomized, Subject- and Evaluator-blind, Paired Study.","authors":"Si-Hyung Lee, Eunsoo Park, Chong Hyun Won","doi":"10.1093/asj/sjag003","DOIUrl":"https://doi.org/10.1093/asj/sjag003","url":null,"abstract":"<p><strong>Background: </strong>Hyaluronic acid (HA) dermal fillers are widely used as a non-surgical treatment for facial aging, including nasolabial folds (NLFs). As demand for convenient aesthetic procedures increases, new HA products require rigorous comparison with established fillers.</p><p><strong>Objectives: </strong>To assess the non-inferiority and safety of a new cross-linked HA filler, SkinPlus-HYAL Implant Lidocaine (test), versus RESTYLANE Lidocaine (control) for temporary correction of moderate to severe NLFs.</p><p><strong>Methods: </strong>In this multicenter, randomized, subject- and evaluator-blinded, split-face study, 100 adults with moderate or severe NLFs received the test filler in one NLF and the control in the contralateral NLF. Efficacy was analyzed in the Full Analysis Set (N=93). The primary endpoint was the between-treatment difference in Wrinkle Severity Rating Scale (WSRS) scores at Week 24. Safety was evaluated in the Safety Set (N=100). Group differences were analyzed using a two-sample t-test.</p><p><strong>Results: </strong>At Week 24, mean WSRS scores were 1.85±0.72 (test) and 1.84±0.68 (control). The mean difference (test - control) was 0.01±0.48, with an upper 97.5% one-sided confidence limit of 0.2136, below the prespecified non-inferiority margin of 0.29. Investigator-rated Global Aesthetic Improvement Scale (GAIS) scores at Week 24 and subject-rated GAIS scores at Week 8 favored the test filler. Local adverse event were more frequent with the test (92.00%) than the control (82.0%), but severe injection-site reactions were uncommon, and no serious adverse events occurred.</p><p><strong>Conclusions: </strong>SkinPlus-HYAL Implant Lidocaine was non-inferior to RESTYLANE Lidocaine for correction of moderate to severe NLFs and maintained efficacy through 48 weeks. Despite a higher rate of local reactions, its overall safety profile was acceptable, supporting its use as an effective, safe option for facial aesthetic augmentation.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical Considerations on the Study of Lunaphil Ultra and Juvéderm Ultra 4 for Nasolabial Folds Treatment. 研究Lunaphil Ultra和juvamoderm Ultra 4治疗鼻唇褶皱的关键考虑。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-07 DOI: 10.1093/asj/sjag001
Lianchu Li, Jing Zhong, Xiyuan Li
{"title":"Critical Considerations on the Study of Lunaphil Ultra and Juvéderm Ultra 4 for Nasolabial Folds Treatment.","authors":"Lianchu Li, Jing Zhong, Xiyuan Li","doi":"10.1093/asj/sjag001","DOIUrl":"https://doi.org/10.1093/asj/sjag001","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145909871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved Infraorbital Hollowing in Chinese Adults Following Hyaluronic Acid-Based Filler With Lidocaine (VYC-15L) Treatment. 透明质酸填充物与利多卡因(VYC-15L)治疗后改善中国成人眶下空穴。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2026-01-07 DOI: 10.1093/asj/sjaf267
Nanze Yu, Xiaojun Wang, Wenyu Wu, Hongyi Zhao, Zhenyu Chen, Yan Wu, Qian Tan, Ziyang Liu, Smita Chawla

Background: Infraorbital hollowing (IOH) is characterized by a sunken appearance of the lower eyelid. The soft-tissue filler VYC-15L has been demonstrated to be effective in correcting IOH in U.S. and European populations.

Objectives: To assess the safety and effectiveness of VYC-15L treatment in Chinese adults with moderate to severe IOH.

Methods: In this randomized, multi-center, 12-month study, the primary endpoint was the proportion of ≥1-grade improvements on the Allergan Infraorbital Hollowing Scale (AIHS) according to the evaluating investigator (EI) at Month 3. Secondary endpoints included EI- and participant-based assessments using the Global Aesthetic Improvement Scale (GAIS) and FACE-Q responses evaluated at Month 3. Safety was monitored throughout.

Results: The primary endpoint was met with a 94.6% AIHS responder rate in the VYC-15L group versus 0.0% in the delayed-treatment control (DTC) group (P < .0001). Significant GAIS improvements in VYC-15L versus DTC participants were seen in EI-assessed (99.1% vs 0.0%) and participant-assessed (95.6% vs 5.7%) responder rates at Month 3 (P < .0001). The mean change in FACE-Q scores was greater in the VYC-15L group compared with the DTC group at Month 3 (P < .0001). Improvements from VYC-15L treatment were seen across all effectiveness measures through Month 12. Mean pain scores were 2.9. Most ISRs were mild and resolved within 14 days. Forty-six participants (28.8%) experienced treatment-emergent AEs (TEAEs), including treatment-related TEAEs (1.7%), which were blepharospasm (0.8%) and injection site bruising (0.8%). No serious TEAEs were reported.

Conclusions: VYC-15L was effective and well tolerated for IOH correction in Chinese adults up to 1 year.

背景:眶下空心症(IOH)以下眼睑凹陷为特征。软组织填充物VYC-15L已被证明在美国和欧洲人群中矫正IOH是有效的。目的:评价VYC-15L治疗中国成人中重度IOH的安全性和有效性。方法:在这项随机、多中心、为期12个月的研究中,主要终点是根据评估研究者(EI)在第3个月时对Allergan眶下空心化量表(AIHS)≥1级改善的比例。次要终点包括基于EI和参与者的评估,使用全球审美改善量表(GAIS)和在第3个月评估的FACE-Q反应。安全受到全程监控。结果:VYC-15L组达到了主要终点,AIHS应答率为94.6%,延迟治疗对照组(DTC)为0.0% (P < 0.0001)。与DTC参与者相比,VYC-15L参与者在第3个月的ei评估(99.1% vs 0.0%)和参与者评估(95.6% vs 5.7%)应答率上的GAIS显著改善(P < 0.0001)。第3个月,VYC-15L组FACE-Q评分的平均变化大于DTC组(P < 0.0001)。在第12个月的所有有效性测量中,VYC-15L治疗均有改善。平均疼痛评分为2.9分。大多数isr是轻微的,在14天内消退。46名参与者(28.8%)经历了治疗突发事件(teae),包括治疗相关的teae(1.7%),即眼睑痉挛(0.8%)和注射部位瘀伤(0.8%)。没有严重的tees报告。结论:VYC-15L对中国成人IOH矫正1年有效且耐受性良好。
{"title":"Improved Infraorbital Hollowing in Chinese Adults Following Hyaluronic Acid-Based Filler With Lidocaine (VYC-15L) Treatment.","authors":"Nanze Yu, Xiaojun Wang, Wenyu Wu, Hongyi Zhao, Zhenyu Chen, Yan Wu, Qian Tan, Ziyang Liu, Smita Chawla","doi":"10.1093/asj/sjaf267","DOIUrl":"https://doi.org/10.1093/asj/sjaf267","url":null,"abstract":"<p><strong>Background: </strong>Infraorbital hollowing (IOH) is characterized by a sunken appearance of the lower eyelid. The soft-tissue filler VYC-15L has been demonstrated to be effective in correcting IOH in U.S. and European populations.</p><p><strong>Objectives: </strong>To assess the safety and effectiveness of VYC-15L treatment in Chinese adults with moderate to severe IOH.</p><p><strong>Methods: </strong>In this randomized, multi-center, 12-month study, the primary endpoint was the proportion of ≥1-grade improvements on the Allergan Infraorbital Hollowing Scale (AIHS) according to the evaluating investigator (EI) at Month 3. Secondary endpoints included EI- and participant-based assessments using the Global Aesthetic Improvement Scale (GAIS) and FACE-Q responses evaluated at Month 3. Safety was monitored throughout.</p><p><strong>Results: </strong>The primary endpoint was met with a 94.6% AIHS responder rate in the VYC-15L group versus 0.0% in the delayed-treatment control (DTC) group (P < .0001). Significant GAIS improvements in VYC-15L versus DTC participants were seen in EI-assessed (99.1% vs 0.0%) and participant-assessed (95.6% vs 5.7%) responder rates at Month 3 (P < .0001). The mean change in FACE-Q scores was greater in the VYC-15L group compared with the DTC group at Month 3 (P < .0001). Improvements from VYC-15L treatment were seen across all effectiveness measures through Month 12. Mean pain scores were 2.9. Most ISRs were mild and resolved within 14 days. Forty-six participants (28.8%) experienced treatment-emergent AEs (TEAEs), including treatment-related TEAEs (1.7%), which were blepharospasm (0.8%) and injection site bruising (0.8%). No serious TEAEs were reported.</p><p><strong>Conclusions: </strong>VYC-15L was effective and well tolerated for IOH correction in Chinese adults up to 1 year.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145909832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Aesthetic Surgery Journal
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