首页 > 最新文献

Aesthetic Surgery Journal最新文献

英文 中文
Looking Better Follows Seeing Better: Exploring Cosmetic Procedure Trends Following Cataract Surgery-A Retrospective Cohort Study. 看得越好,看得越好:探索白内障手术后的美容手术趋势-一项回顾性队列研究。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-27 DOI: 10.1093/asj/sjaf251
Wei-Ying Chien, Kee-Hsin Chen, Jin-Hua Chen, Yi-No Kang, Min-Huei Hsu, Hoang Khanh Dinh, Chiehfeng Chen

Background: Cataract surgery, one of the most commonly performed surgery worldwide, not only restores visual function but may also influence patients' psychosocial behavior.

Objectives: This study aimed to investigate whether cataract surgery influences the trend for cosmetic surgery, particularly facial aesthetic procedures, by utilizing the TriNetX database. We hypothesized that improved postoperative vision may prompt patients to seek cosmetic procedures due to the change of self-perception.

Methods: We conducted a retrospective cohort study using the TriNetX US Collaborative Network. Two cohorts were defined: patients with cataract extraction status (CES) and those who did not (nCES). 1:1 propensity score matching was applied. We assessed the relative risk (RR) of cosmetic procedures and applied Cox proportional hazards models to identify independent predictors of blepharoplasty. Adverse events, including dry eye syndrome and visual disturbances, were evaluated in the CES subgroup.

Results: Patients in the CES cohort were significantly more likely to undergo blepharoplasty (RR: 1.83, 95% CI: 1.70-1.96) and rhytidectomy (RR: 1.67, 95% CI: 1.22-2.28). Adverse events, including dry eye syndrome (RR: 1.80, 95% CI: 1.66-1.95) and impaired vision (RR: 1.35, 95% CI: 1.24-1.47), were observed more frequently in patients undergoing blepharoplasty post-cataract surgery. Multivariable Cox regression confirmed cataract surgery as an independent predictor of blepharoplasty (HR: 6.31, 95% CI: 2.57-15.50, p < 0.0001).

Conclusions: Cataract surgery is associated with an increased trend for certain cosmetic surgeries, particularly facial procedures. However, blepharoplasty after cataract surgery may elevate the risk of ocular complications, emphasizing the need for careful postoperative care.

背景:白内障手术是世界范围内最常见的手术之一,它不仅可以恢复视力,而且可以影响患者的社会心理行为。目的:本研究旨在利用TriNetX数据库,探讨白内障手术是否会影响整容手术的趋势,特别是面部美容手术。我们假设术后视力的改善可能会促使患者因自我认知的改变而寻求整容手术。方法:我们使用TriNetX美国协作网络进行了一项回顾性队列研究。定义了两个队列:有白内障摘除状态(CES)的患者和没有白内障摘除状态(nCES)的患者。采用1:1倾向评分匹配。我们评估了美容手术的相对风险(RR),并应用Cox比例风险模型来确定眼睑成形术的独立预测因素。不良事件,包括干眼综合征和视力障碍,在CES亚组中进行评估。结果:CES队列患者接受眼睑成形术(RR: 1.83, 95% CI: 1.70-1.96)和除皱术(RR: 1.67, 95% CI: 1.22-2.28)的可能性显著增加。不良事件,包括干眼综合征(RR: 1.80, 95% CI: 1.66-1.95)和视力受损(RR: 1.35, 95% CI: 1.24-1.47),在白内障术后进行眼睑成形术的患者中观察到的频率更高。多变量Cox回归证实白内障手术是眼睑成形术的独立预测因素(HR: 6.31, 95% CI: 2.57-15.50, p < 0.0001)。结论:白内障手术与某些整容手术,特别是面部手术的增加趋势有关。然而,白内障手术后眼睑成形术可能会增加眼部并发症的风险,强调需要仔细的术后护理。
{"title":"Looking Better Follows Seeing Better: Exploring Cosmetic Procedure Trends Following Cataract Surgery-A Retrospective Cohort Study.","authors":"Wei-Ying Chien, Kee-Hsin Chen, Jin-Hua Chen, Yi-No Kang, Min-Huei Hsu, Hoang Khanh Dinh, Chiehfeng Chen","doi":"10.1093/asj/sjaf251","DOIUrl":"https://doi.org/10.1093/asj/sjaf251","url":null,"abstract":"<p><strong>Background: </strong>Cataract surgery, one of the most commonly performed surgery worldwide, not only restores visual function but may also influence patients' psychosocial behavior.</p><p><strong>Objectives: </strong>This study aimed to investigate whether cataract surgery influences the trend for cosmetic surgery, particularly facial aesthetic procedures, by utilizing the TriNetX database. We hypothesized that improved postoperative vision may prompt patients to seek cosmetic procedures due to the change of self-perception.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using the TriNetX US Collaborative Network. Two cohorts were defined: patients with cataract extraction status (CES) and those who did not (nCES). 1:1 propensity score matching was applied. We assessed the relative risk (RR) of cosmetic procedures and applied Cox proportional hazards models to identify independent predictors of blepharoplasty. Adverse events, including dry eye syndrome and visual disturbances, were evaluated in the CES subgroup.</p><p><strong>Results: </strong>Patients in the CES cohort were significantly more likely to undergo blepharoplasty (RR: 1.83, 95% CI: 1.70-1.96) and rhytidectomy (RR: 1.67, 95% CI: 1.22-2.28). Adverse events, including dry eye syndrome (RR: 1.80, 95% CI: 1.66-1.95) and impaired vision (RR: 1.35, 95% CI: 1.24-1.47), were observed more frequently in patients undergoing blepharoplasty post-cataract surgery. Multivariable Cox regression confirmed cataract surgery as an independent predictor of blepharoplasty (HR: 6.31, 95% CI: 2.57-15.50, p < 0.0001).</p><p><strong>Conclusions: </strong>Cataract surgery is associated with an increased trend for certain cosmetic surgeries, particularly facial procedures. However, blepharoplasty after cataract surgery may elevate the risk of ocular complications, emphasizing the need for careful postoperative care.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness and Safety of a Polyvinyl Alcohol Microsphere and Hyaluronic Acid Suspension for Chin Augmentation: A Randomized Controlled Trial and Multidisciplinary Study. 聚乙烯醇微球和透明质酸悬浮液的有效性和安全性:一项随机对照试验和多学科研究。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-27 DOI: 10.1093/asj/sjaf250
Wei-Jin Hong, Ji-Zhen Ren, Cheng-Yuan Wang, Shi-Wei Wang, Kun Zhang, Zhen-Yu Chen, Mu-Yan Zou, Jia-Hua Cao, Huan-Yun Niu, Sheng-Kang Luo

Background: Dermal fillers are a primary treatment for chin retrusion. However, current options have limitations in longevity and biomechanical properties.

Objectives: To evaluate the efficacy and safety of a novel filler, comprised of polyvinyl alcohol (PVA) microspheres suspended in hyaluronic acid (PVA-HA), for chin augmentation..

Methods: The physicochemical properties of PVA were were compared to traditional filler materials using contact angle, Young's modulus, friction-wear, and scanning electron microscopy tests. Biocompatibility was assessed in animal models via histopathological and immunofluorescence analyses. Subsequently, a prospective, randomized controlled trial was conducted from June 2021 to March 2023 in 144 subjects with chin retrusion, randomized 3:1 to receive PVA-HA or no treatment. Efficacy was assessed by changes in the Glabella-Subnasale-Pogonion (G-sn-Pog') angle, a chin retrusion scale and Global Aesthetic Improvement Scale (GAIS).

Results: Preclinical tests demonstrated that PVA microspheres had favorable hydrophilicity, softness, and mechanical properties comparable to natural periosteum. In animal models, PVA-HA exhibited excellent biocompatibility with only a mild, transient inflammatory response. In the clinical trial, the PVA-HA group showed a mean G-sn-Pog' angle increase of 1.12° (95% Confidence Interval [CI]: 0.83°, 1.41°) at 60 weeks, compared to a mean decrease of 0.42° (95% CI: -0.87°, 0.03°) in the control group (between-group difference, 1.54°; p<0.01). Significant improvements were also observed on GAIS and chin retrusion scale (both p<0.001). Adverse events were primarily mild-to-moderate, transient injection site responses.

Conclusions: The novel PVA-HA filler demonstrates favorable physicochemical and biocompatibility properties. It provides clinically significant and safe outcomes in chin augmentation, representing a promising new option for soft tissue filling.

背景:真皮填充物是治疗下巴后缩的主要方法。然而,目前的选择在寿命和生物力学性能方面存在局限性。目的:评价聚乙烯醇(PVA)微球悬浮在透明质酸(PVA- ha)中的新型填充剂对下颌隆胸的有效性和安全性。方法:采用接触角、杨氏模量、摩擦磨损、扫描电镜等测试方法比较PVA与传统填充材料的理化性能。通过组织病理学和免疫荧光分析评估动物模型的生物相容性。随后,从2021年6月至2023年3月,对144名下颌后缩患者进行了一项前瞻性随机对照试验,随机3:1接受PVA-HA治疗或不接受治疗。通过glabella - sub鼻下- pogonion (G-sn-Pog')角度的变化、下巴后缩量表和整体美学改善量表(GAIS)来评估疗效。结果:临床前试验表明,PVA微球具有良好的亲水性、柔软性和与天然骨膜相当的机械性能。在动物模型中,PVA-HA表现出良好的生物相容性,只有轻微的、短暂的炎症反应。在临床试验中,PVA-HA组在60周的G-sn-Pog′角平均增加1.12°(95%可信区间[CI]: 0.83°,1.41°),而对照组的G-sn-Pog′角平均减少0.42°(95% CI: -0.87°,0.03°)(组间差异为1.54°)。结论:新型PVA-HA填料具有良好的物理化学和生物相容性。它提供了临床显著和安全的结果在下巴增大,代表了一个有前途的新的选择软组织填充。
{"title":"Effectiveness and Safety of a Polyvinyl Alcohol Microsphere and Hyaluronic Acid Suspension for Chin Augmentation: A Randomized Controlled Trial and Multidisciplinary Study.","authors":"Wei-Jin Hong, Ji-Zhen Ren, Cheng-Yuan Wang, Shi-Wei Wang, Kun Zhang, Zhen-Yu Chen, Mu-Yan Zou, Jia-Hua Cao, Huan-Yun Niu, Sheng-Kang Luo","doi":"10.1093/asj/sjaf250","DOIUrl":"https://doi.org/10.1093/asj/sjaf250","url":null,"abstract":"<p><strong>Background: </strong>Dermal fillers are a primary treatment for chin retrusion. However, current options have limitations in longevity and biomechanical properties.</p><p><strong>Objectives: </strong>To evaluate the efficacy and safety of a novel filler, comprised of polyvinyl alcohol (PVA) microspheres suspended in hyaluronic acid (PVA-HA), for chin augmentation..</p><p><strong>Methods: </strong>The physicochemical properties of PVA were were compared to traditional filler materials using contact angle, Young's modulus, friction-wear, and scanning electron microscopy tests. Biocompatibility was assessed in animal models via histopathological and immunofluorescence analyses. Subsequently, a prospective, randomized controlled trial was conducted from June 2021 to March 2023 in 144 subjects with chin retrusion, randomized 3:1 to receive PVA-HA or no treatment. Efficacy was assessed by changes in the Glabella-Subnasale-Pogonion (G-sn-Pog') angle, a chin retrusion scale and Global Aesthetic Improvement Scale (GAIS).</p><p><strong>Results: </strong>Preclinical tests demonstrated that PVA microspheres had favorable hydrophilicity, softness, and mechanical properties comparable to natural periosteum. In animal models, PVA-HA exhibited excellent biocompatibility with only a mild, transient inflammatory response. In the clinical trial, the PVA-HA group showed a mean G-sn-Pog' angle increase of 1.12° (95% Confidence Interval [CI]: 0.83°, 1.41°) at 60 weeks, compared to a mean decrease of 0.42° (95% CI: -0.87°, 0.03°) in the control group (between-group difference, 1.54°; p<0.01). Significant improvements were also observed on GAIS and chin retrusion scale (both p<0.001). Adverse events were primarily mild-to-moderate, transient injection site responses.</p><p><strong>Conclusions: </strong>The novel PVA-HA filler demonstrates favorable physicochemical and biocompatibility properties. It provides clinically significant and safe outcomes in chin augmentation, representing a promising new option for soft tissue filling.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145626947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Quality and Reliability of Large Language Models for Plastic Surgery Patient Education: A Comparative Analysis of ChatGPT and OpenEvidence. 评估整形外科患者教育大型语言模型的质量和可靠性:ChatGPT和OpenEvidence的比较分析。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-26 DOI: 10.1093/asj/sjaf249
Lucas R Perez Rivera, Alexis K Gursky, Nicholas Elmer, Carter J Boyd, Nolan S Karp

Background: Concerns regarding information inaccuracy when using general-purpose large language models have prompted the quest for alternative tools. OpenEvidence has emerged as a healthcare-focused large language model trained exclusively on data from peer-reviewed medical literature.

Objectives: This study compared the quality, accuracy, and readability of aesthetic surgery patient education materials generated by OpenEvidence and ChatGPT.

Methods: A standardized prompt requesting comprehensive postoperative discharge instructions for twenty of the most common aesthetic surgery procedures was entered into OpenEvidence and ChatGPT-5. Outputs were evaluated using four validated assessment tools: the DISCERN instrument for information quality (1-5), the Patient Education Materials Assessment Tool for Printable Materials (PEMAT-P) for information understandability and actionability (0-100), the Flesch-Kincaid scale for estimated grade level (fifth grade to professional level) and reading ease (0-100), and a Likert scale for citation accuracy (1-4).

Results: OpenEvidence scored significantly higher than ChatGPT-5 in DISCERN (3.3 ± 0.4 vs. 1.7 ± 0.4, p<0.001) and the citation accuracy scale (2.4 ±1.3 vs. 1.5 ± 0.7, p=0.007). Scores were comparable among both tools in PEMAT-P understandability (71 ± 5 vs. 69 ± 0, p=0.3) and actionability (52 ± 12 vs. 54 ± 5, p=0.6), as well as on the Flesch Kincaid Grade Level (9.3 ± 1.0 vs. 9.2 ± 0.6, p=0.8) and the Flesch Reading Ease Score (40.0 ± 6.6 vs. 41.0 ± 5.5, p=0.6).

Conclusions: OpenEvidence generated materials of significantly higher quality and reliability than ChatGPT, suggesting it may serve as a more reliable alternative for patient education in aesthetic surgery practice.

背景:在使用通用大型语言模型时,对信息不准确性的担忧促使人们寻求替代工具。OpenEvidence是一个专注于医疗保健的大型语言模型,专门训练来自同行评议医学文献的数据。目的:本研究比较了OpenEvidence和ChatGPT生成的美容外科患者教育材料的质量、准确性和可读性。方法:在OpenEvidence和ChatGPT-5中输入标准化提示,要求对20种最常见的美容手术程序进行全面的术后出院说明。使用四种经过验证的评估工具对输出进行评估:用于信息质量的DISCERN工具(1-5),用于信息可理解性和可操作性的患者教育材料评估工具(PEMAT-P)(0-100),用于估计年级水平(五年级到专业水平)和阅读难度(0-100)的Flesch-Kincaid量表,以及用于引用准确性的Likert量表(1-4)。结果:OpenEvidence在DISCERN中的得分明显高于ChatGPT-5(3.3±0.4比1.7±0.4)。结论:OpenEvidence生成的材料质量和可靠性明显高于ChatGPT,表明它可以作为美容外科实践中患者教育的更可靠的替代方案。
{"title":"Evaluating the Quality and Reliability of Large Language Models for Plastic Surgery Patient Education: A Comparative Analysis of ChatGPT and OpenEvidence.","authors":"Lucas R Perez Rivera, Alexis K Gursky, Nicholas Elmer, Carter J Boyd, Nolan S Karp","doi":"10.1093/asj/sjaf249","DOIUrl":"https://doi.org/10.1093/asj/sjaf249","url":null,"abstract":"<p><strong>Background: </strong>Concerns regarding information inaccuracy when using general-purpose large language models have prompted the quest for alternative tools. OpenEvidence has emerged as a healthcare-focused large language model trained exclusively on data from peer-reviewed medical literature.</p><p><strong>Objectives: </strong>This study compared the quality, accuracy, and readability of aesthetic surgery patient education materials generated by OpenEvidence and ChatGPT.</p><p><strong>Methods: </strong>A standardized prompt requesting comprehensive postoperative discharge instructions for twenty of the most common aesthetic surgery procedures was entered into OpenEvidence and ChatGPT-5. Outputs were evaluated using four validated assessment tools: the DISCERN instrument for information quality (1-5), the Patient Education Materials Assessment Tool for Printable Materials (PEMAT-P) for information understandability and actionability (0-100), the Flesch-Kincaid scale for estimated grade level (fifth grade to professional level) and reading ease (0-100), and a Likert scale for citation accuracy (1-4).</p><p><strong>Results: </strong>OpenEvidence scored significantly higher than ChatGPT-5 in DISCERN (3.3 ± 0.4 vs. 1.7 ± 0.4, p<0.001) and the citation accuracy scale (2.4 ±1.3 vs. 1.5 ± 0.7, p=0.007). Scores were comparable among both tools in PEMAT-P understandability (71 ± 5 vs. 69 ± 0, p=0.3) and actionability (52 ± 12 vs. 54 ± 5, p=0.6), as well as on the Flesch Kincaid Grade Level (9.3 ± 1.0 vs. 9.2 ± 0.6, p=0.8) and the Flesch Reading Ease Score (40.0 ± 6.6 vs. 41.0 ± 5.5, p=0.6).</p><p><strong>Conclusions: </strong>OpenEvidence generated materials of significantly higher quality and reliability than ChatGPT, suggesting it may serve as a more reliable alternative for patient education in aesthetic surgery practice.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supramastoid Fascia as an Autologous Donor Site Alternative for Moderate Dorsal Augmentation: A Multicenter Prospective Study. 乳突上筋膜作为自体供体部位中等背隆术的选择:一项多中心前瞻性研究。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-25 DOI: 10.1093/asj/sjaf248
Yang Hu, Chengwu Zhang, Yonggan Niu, Xiangyu Chen, Ziqiang Zhou, Songrui Zhang, Sijia Zhou, Jianda Zhou, Ping Li

Background: Autologous fascia has been widely applied in rhinoplasty, yet prospective data on the supramastoid donor site remain scarce. This region provides a dense, pliable fascial layer with concealed scarring, potentially suitable for moderate nasal dorsal augmentation.

Objectives: To prospectively evaluate the clinical outcomes, long-term stability, and patient satisfaction of supramastoid fascia as an autologous graft material for dorsal augmentation.

Methods: This multicenter observational study enrolled patients between June 2022 and April 2024. Dorsal projection and fascial thickness were measured by 3D photogrammetry and 15-MHz ultrasound at 1, 6, 12, 24, and 36 months, with patient satisfaction assessed using the FACE-Q Rhinoplasty Module. Longitudinal changes were analyzed using repeated-measures ANOVA and linear mixed-effects models.

Results: Among 73 patients, 67 (91.8%) completed ≥12 months of follow-up; 65% were observed beyond 24 months and 19% to ≥36 months. Dorsal height increased significantly at 1 month and remained stable through 36 months (P > 0.05 after 12 months). Mean resorption rate was 8.6 ± 3.7% at 12 months and 9.4 ± 4.1% at 36 months. FACE-Q satisfaction scores remained >80 across all domains without late decline. No graft displacement, irregularity, or donor-site morbidity was observed.

Conclusions: The supramastoid fascia is a practical, minimally invasive autologous donor-site alternative for moderate dorsal augmentation, showing stable projection and high satisfaction through 36 months. Longer follow-up and multi-ethnic cohorts are warranted.

背景:自体筋膜已广泛应用于鼻整形术,但关于乳突肌上供体部位的前瞻性数据仍然很少。这个区域提供了一个致密的,柔韧的筋膜层和隐藏的疤痕,可能适合适度的鼻背增强。目的:前瞻性评价乳突上筋膜作为自体背隆术移植材料的临床效果、长期稳定性和患者满意度。方法:这项多中心观察性研究于2022年6月至2024年4月招募患者。在1、6、12、24和36个月时,通过3D摄影测量和15 mhz超声测量背侧投影和筋膜厚度,并使用FACE-Q鼻整形模块评估患者满意度。采用重复测量方差分析和线性混合效应模型分析纵向变化。结果:73例患者中,67例(91.8%)完成≥12个月的随访;65%的患者超过24个月,19%的患者≥36个月。背高在1个月时显著升高,在36个月时保持稳定(12个月后P < 0.05)。12个月时平均吸收率8.6±3.7%,36个月时平均吸收率9.4±4.1%。所有领域的FACE-Q满意度得分保持在80分左右,没有后期下降。未观察到移植物移位、不规则或供体部位发病率。结论:乳突上筋膜是一种实用的、微创的自体供体部位选择,可用于适度的背隆术,36个月后投射稳定,满意度高。需要更长时间的随访和多种族队列。
{"title":"Supramastoid Fascia as an Autologous Donor Site Alternative for Moderate Dorsal Augmentation: A Multicenter Prospective Study.","authors":"Yang Hu, Chengwu Zhang, Yonggan Niu, Xiangyu Chen, Ziqiang Zhou, Songrui Zhang, Sijia Zhou, Jianda Zhou, Ping Li","doi":"10.1093/asj/sjaf248","DOIUrl":"https://doi.org/10.1093/asj/sjaf248","url":null,"abstract":"<p><strong>Background: </strong>Autologous fascia has been widely applied in rhinoplasty, yet prospective data on the supramastoid donor site remain scarce. This region provides a dense, pliable fascial layer with concealed scarring, potentially suitable for moderate nasal dorsal augmentation.</p><p><strong>Objectives: </strong>To prospectively evaluate the clinical outcomes, long-term stability, and patient satisfaction of supramastoid fascia as an autologous graft material for dorsal augmentation.</p><p><strong>Methods: </strong>This multicenter observational study enrolled patients between June 2022 and April 2024. Dorsal projection and fascial thickness were measured by 3D photogrammetry and 15-MHz ultrasound at 1, 6, 12, 24, and 36 months, with patient satisfaction assessed using the FACE-Q Rhinoplasty Module. Longitudinal changes were analyzed using repeated-measures ANOVA and linear mixed-effects models.</p><p><strong>Results: </strong>Among 73 patients, 67 (91.8%) completed ≥12 months of follow-up; 65% were observed beyond 24 months and 19% to ≥36 months. Dorsal height increased significantly at 1 month and remained stable through 36 months (P > 0.05 after 12 months). Mean resorption rate was 8.6 ± 3.7% at 12 months and 9.4 ± 4.1% at 36 months. FACE-Q satisfaction scores remained >80 across all domains without late decline. No graft displacement, irregularity, or donor-site morbidity was observed.</p><p><strong>Conclusions: </strong>The supramastoid fascia is a practical, minimally invasive autologous donor-site alternative for moderate dorsal augmentation, showing stable projection and high satisfaction through 36 months. Longer follow-up and multi-ethnic cohorts are warranted.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145601665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving Volumetric Symmetry in Reduction Mammoplasty Using Intraoperative 3-Dimensional Photogrammetry. 术中三维摄影测量改善缩乳术体积对称性。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-25 DOI: 10.1093/asj/sjaf247
Thomas Holzbach, Katarina Danuser, Rafael Loucas, Riccardo Enzo Giunta, Sebastian Leitsch

Background: Achieving breast symmetry represents a critical endpoint in reduction mammoplasty. Historically, surgeons have been predominantly depended on anthropometric parameters, such as linear measurements and tactile evaluation, to guide intraoperative decision-making. Nonetheless, there remains a substantial unmet need for objective, intraoperative volumetric assessment techniques. While three-dimensional volumetric analyses have become well-established tools for preoperative planning and postoperative evaluation, the literature on intraoperative volumetric assessment is still quite limited and relies on scanning devices lacking rigorous validation.

Objectives: In this study, following extensive preliminary investigations, we present the first evaluation of the validated Vectra H2 3D photogrammetric imaging system applied intraoperatively during reduction mammoplasty. The primary aim was to investigate if integrating this objective intraoperative volumetric data could facilitate improved postoperative breast volume symmetry.

Methods: We analysed 100 patients undergoing reduction mammoplasty with supero-medial pedicle and wise pattern skin resection. We compared volumetric differences of the last 50 reduction mammoplasty procedures before using intraoperative volumetric measurements (group A; control) to the first 50 reduction mammoplasties after implementation of intraoperative volumetric analysis using Vectra H2 3D photogrammetry (group B; intraoperative 3D). The follow-up period was 12 months.

Results: 50 patients were included in group A and 50 patients in group B. Patient demographics, mean resection weight and complications did not differ statistically significantly. The 3-month-postoperative volumetric differences between the breasts of the same patient averaged 5.8% ± 3.0% (mean ± SD, 0.1% - 12.2%) in Group A (control) and 2.9% ± 1.5% (mean ± SD, 0.8% - 6.9%; ) in Group B (intraoperative 3D). These differences were statistically significant (p<0.05).

Conclusions: In our study, intraoperative 3D photogrammetry for volumetric analysis significantly improved volumetric symmetry following reduction mammoplasty. Although the volumetric differences in both groups were relatively small, the technique facilitated the intraoperative identification of outliers and resulted in superior volumetric symmetry.

背景:实现乳房对称是缩小乳房成形术的关键终点。从历史上看,外科医生主要依靠人体测量参数,如线性测量和触觉评估,来指导术中决策。尽管如此,对于客观的术中体积评估技术的需求仍未得到满足。虽然三维体积分析已经成为术前规划和术后评估的完善工具,但术中体积评估的文献仍然相当有限,并且依赖于缺乏严格验证的扫描设备。目的:在本研究中,经过广泛的初步调查,我们首次对经验证的Vectra H2 3D摄影测量成像系统在缩乳术中应用进行了评估。主要目的是研究整合这些客观的术中体积数据是否有助于改善术后乳房体积对称性。方法:对100例行上内侧蒂缩乳术和明智模式皮肤切除术的患者进行分析。我们比较了术中体积测量前的最后50例缩位乳房成形术(A组,对照组)和术中体积分析后的前50例缩位乳房成形术(B组,术中3D)的体积差异。随访期为12个月。结果:A组50例,b组50例。患者人口统计学、平均切除重量、并发症无统计学差异。A组(对照组)术后3个月同一患者乳房间体积差异平均为5.8%±3.0%(平均±SD, 0.1% - 12.2%), 2.9%±1.5%(平均±SD, 0.8% - 6.9%;)B组(术中3D)。结论:在我们的研究中,术中用于体积分析的3D摄影测量显着改善了缩乳术后的体积对称性。虽然两组的体积差异相对较小,但该技术有助于术中识别异常值,并导致更好的体积对称性。
{"title":"Improving Volumetric Symmetry in Reduction Mammoplasty Using Intraoperative 3-Dimensional Photogrammetry.","authors":"Thomas Holzbach, Katarina Danuser, Rafael Loucas, Riccardo Enzo Giunta, Sebastian Leitsch","doi":"10.1093/asj/sjaf247","DOIUrl":"https://doi.org/10.1093/asj/sjaf247","url":null,"abstract":"<p><strong>Background: </strong>Achieving breast symmetry represents a critical endpoint in reduction mammoplasty. Historically, surgeons have been predominantly depended on anthropometric parameters, such as linear measurements and tactile evaluation, to guide intraoperative decision-making. Nonetheless, there remains a substantial unmet need for objective, intraoperative volumetric assessment techniques. While three-dimensional volumetric analyses have become well-established tools for preoperative planning and postoperative evaluation, the literature on intraoperative volumetric assessment is still quite limited and relies on scanning devices lacking rigorous validation.</p><p><strong>Objectives: </strong>In this study, following extensive preliminary investigations, we present the first evaluation of the validated Vectra H2 3D photogrammetric imaging system applied intraoperatively during reduction mammoplasty. The primary aim was to investigate if integrating this objective intraoperative volumetric data could facilitate improved postoperative breast volume symmetry.</p><p><strong>Methods: </strong>We analysed 100 patients undergoing reduction mammoplasty with supero-medial pedicle and wise pattern skin resection. We compared volumetric differences of the last 50 reduction mammoplasty procedures before using intraoperative volumetric measurements (group A; control) to the first 50 reduction mammoplasties after implementation of intraoperative volumetric analysis using Vectra H2 3D photogrammetry (group B; intraoperative 3D). The follow-up period was 12 months.</p><p><strong>Results: </strong>50 patients were included in group A and 50 patients in group B. Patient demographics, mean resection weight and complications did not differ statistically significantly. The 3-month-postoperative volumetric differences between the breasts of the same patient averaged 5.8% ± 3.0% (mean ± SD, 0.1% - 12.2%) in Group A (control) and 2.9% ± 1.5% (mean ± SD, 0.8% - 6.9%; ) in Group B (intraoperative 3D). These differences were statistically significant (p<0.05).</p><p><strong>Conclusions: </strong>In our study, intraoperative 3D photogrammetry for volumetric analysis significantly improved volumetric symmetry following reduction mammoplasty. Although the volumetric differences in both groups were relatively small, the technique facilitated the intraoperative identification of outliers and resulted in superior volumetric symmetry.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145601701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secondary Augmentation-mastopexy: Outcome Analysis of 1,664 Consecutive Procedures. 二次隆乳-乳房切除术:1,664例连续手术的结果分析。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-20 DOI: 10.1093/asj/sjaf236
Charles A Messa, Jessica Bereszniewicz, Charles A Messa

Background: The efficacy of one-stage augmentation mastopexy has been well established throughout the literature. Limited evidence exists examining outcomes in the secondary augmentation mastopexy patient.

Objectives: To evaluate the long-term safety and efficacy of secondary augmentation mastopexy through an analysis of clinical outcomes.

Methods: A retrospective review of 847 patients who underwent 1664 consecutive secondary augmentation mastopexy procedures from January 2009 to January 2021 was performed. Demographics, operative characteristics, and post-operative outcomes, including complication and re-operation rate were collected and analyzed.

Results: Over a mean follow-up period of 47 months (3 to 131 months), the complication rate was 11% (n = 94) with a reoperation rate of 8.7% (n = 74). Tissue related complications occurred in 7.3% (n = 62) and implant related complications in 3.8% (n =32). Indications for reoperation were primarily due to tissue-related complications in 5.4% (n=46), most commonly recurrent ptosis in 3.4% (n=29). Implant-related indications for reoperation (3.3%, n=28) were most commonly capsular contracture (Baker III or IV) (n=21, 2.5%) and implant malposition in (n=11, 1.3%). Comparing the incidence of reoperation with the number of previous breast procedures, identified a significant increase in re-operation rate for patients with 3 or more previous breast implant procedures (p=0.041), as well as a significantly higher re-operation rate in patients with a history of tobacco use (p =0.013).

Conclusions: Secondary augmentation mastopexy can be performed safely with low complication and reoperation rates. Success with this procedure is directly proportional to control of the soft tissue envelope, implant, pocket, and the nipple to inframammary fold distance. An individualized approach coupled with a thorough preoperative evaluation of these components should be employed for optimal results.

背景:一期乳房隆胸术的疗效已经在文献中得到了很好的证实。有限的证据存在于检查二次乳房隆胸患者的结果。目的:通过临床结果分析,评价二次隆胸术的长期安全性和有效性。方法:回顾性分析2009年1月至2021年1月期间接受1664例连续二次乳房隆胸手术的847例患者。收集和分析统计资料、手术特点和术后结果,包括并发症和再手术率。结果:平均随访47个月(3 ~ 131个月),并发症发生率为11% (n = 94),再手术率为8.7% (n = 74)。组织相关并发症占7.3% (n = 62),种植体相关并发症占3.8% (n =32)。再手术指征以组织相关并发症为主,占5.4% (n=46),最常见的是复发性上睑下垂占3.4% (n=29)。再次手术与种植体相关的适应症(3.3%,n=28)最常见的是囊膜挛缩(Baker III或IV) (n=21, 2.5%)和种植体错位(n=11, 1.3%)。将再手术发生率与既往乳房手术次数进行比较,发现3次及以上隆胸手术患者的再手术率显著增加(p=0.041),有吸烟史患者的再手术率显著增加(p= 0.013)。结论:乳房二次隆乳术安全可靠,并发症少,再手术率低。手术的成功与否与控制软组织包膜、植入物、口袋以及乳头到乳下褶皱的距离成正比。个体化的治疗方法与术前对这些成分的全面评估相结合,才能获得最佳效果。
{"title":"Secondary Augmentation-mastopexy: Outcome Analysis of 1,664 Consecutive Procedures.","authors":"Charles A Messa, Jessica Bereszniewicz, Charles A Messa","doi":"10.1093/asj/sjaf236","DOIUrl":"https://doi.org/10.1093/asj/sjaf236","url":null,"abstract":"<p><strong>Background: </strong>The efficacy of one-stage augmentation mastopexy has been well established throughout the literature. Limited evidence exists examining outcomes in the secondary augmentation mastopexy patient.</p><p><strong>Objectives: </strong>To evaluate the long-term safety and efficacy of secondary augmentation mastopexy through an analysis of clinical outcomes.</p><p><strong>Methods: </strong>A retrospective review of 847 patients who underwent 1664 consecutive secondary augmentation mastopexy procedures from January 2009 to January 2021 was performed. Demographics, operative characteristics, and post-operative outcomes, including complication and re-operation rate were collected and analyzed.</p><p><strong>Results: </strong>Over a mean follow-up period of 47 months (3 to 131 months), the complication rate was 11% (n = 94) with a reoperation rate of 8.7% (n = 74). Tissue related complications occurred in 7.3% (n = 62) and implant related complications in 3.8% (n =32). Indications for reoperation were primarily due to tissue-related complications in 5.4% (n=46), most commonly recurrent ptosis in 3.4% (n=29). Implant-related indications for reoperation (3.3%, n=28) were most commonly capsular contracture (Baker III or IV) (n=21, 2.5%) and implant malposition in (n=11, 1.3%). Comparing the incidence of reoperation with the number of previous breast procedures, identified a significant increase in re-operation rate for patients with 3 or more previous breast implant procedures (p=0.041), as well as a significantly higher re-operation rate in patients with a history of tobacco use (p =0.013).</p><p><strong>Conclusions: </strong>Secondary augmentation mastopexy can be performed safely with low complication and reoperation rates. Success with this procedure is directly proportional to control of the soft tissue envelope, implant, pocket, and the nipple to inframammary fold distance. An individualized approach coupled with a thorough preoperative evaluation of these components should be employed for optimal results.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145556169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Study of the Safety and Effectiveness of Motiva SmoothSilk Silicone Gel-filled Breast Implants in Patients Undergoing Primary and Revisional Breast Augmentation: 5-Year Clinical Data. Motiva滑丝硅胶填充假体在初次隆胸和改进型隆胸患者中的安全性和有效性研究:5年临床数据。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-20 DOI: 10.1093/asj/sjaf245
Caroline Glicksman, Andrew Wolfe, Patricia McGuire

Background: The FDA requires implant manufacturers to continue collecting safety and efficacy data annually through year ten. Investigators are encouraged to follow their enrolled subjects in person to obtain the most accurate and complete data.

Objectives: The authors reviewed the 5-year data on the safety and effectiveness of Motiva SmoothSilk® silicone gel filled breast implants submitted to the FDA. The reported data includes both the Primary and Revision Breast Augmentation cohorts.

Methods: The five-year clinical data from the breast augmentation cohorts of the Motiva IDE, 10-year pivotal study was submitted to the FDA in 2024. Data was collected from on adverse events, reoperation, patient and physician satisfaction, connective tissue and rheumatologic diseases, and quality of life instruments. MRIs were obtained at years 1, 2, 3, and 5 for patients enrolled in the MRI sub-study.

Results: There were 451 primary augmentation patients and 109 revision augmentation patients enrolled in the pivotal study. Follow-up rates were 87% of expected patients at both years 4 and 5. Of the 218 patients enrolled in the MRI cohort, 152 underwent MRI screening at year 5, an overall compliance of 79.2% of expected screenings. The reported re-operation rates for any reason were 8.8% in the Primary Augmentation Cohort and 36.0% in the Revision Augmentation Cohort.

Conclusions: The five-year data from the Primary and Revision Breast Augmentation cohorts reveal low rates of device rupture. Size change and malposition were the most common causes of reoperation in the Primary Augmentation Cohort, while capsular contracture and size change were the leading drivers of reoperation in the Revision Augmentation Cohort.

背景:FDA要求植入物制造商每年继续收集安全性和有效性数据,直到第10年。研究者被鼓励亲自跟踪他们登记的受试者,以获得最准确和完整的数据。目的:作者回顾了向FDA提交的关于Motiva SmoothSilk®硅凝胶填充乳房植入物的5年安全性和有效性的数据。报告的数据包括初级和改良隆胸队列。方法:来自Motiva IDE的隆胸队列的5年临床数据,10年关键研究于2024年提交给FDA。收集的数据包括不良事件、再手术、患者和医生满意度、结缔组织和风湿病以及生活质量仪器。在第1、2、3和5年对参加MRI亚研究的患者进行MRI检查。结果:有451例初次隆胸患者和109例改良隆胸患者参加了关键研究。第4年和第5年的随访率均为预期患者的87%。在纳入MRI队列的218例患者中,152例在第5年接受了MRI筛查,总体依从性为预期筛查的79.2%。报告的任何原因的再手术率在初级增强组为8.8%,在修订增强组为36.0%。结论:原发性和改进型隆胸队列的5年数据显示器械破裂率较低。在初级增强组中,大小改变和位置错位是导致再次手术的最常见原因,而在改良增强组中,囊膜挛缩和大小改变是导致再次手术的主要原因。
{"title":"The Study of the Safety and Effectiveness of Motiva SmoothSilk Silicone Gel-filled Breast Implants in Patients Undergoing Primary and Revisional Breast Augmentation: 5-Year Clinical Data.","authors":"Caroline Glicksman, Andrew Wolfe, Patricia McGuire","doi":"10.1093/asj/sjaf245","DOIUrl":"https://doi.org/10.1093/asj/sjaf245","url":null,"abstract":"<p><strong>Background: </strong>The FDA requires implant manufacturers to continue collecting safety and efficacy data annually through year ten. Investigators are encouraged to follow their enrolled subjects in person to obtain the most accurate and complete data.</p><p><strong>Objectives: </strong>The authors reviewed the 5-year data on the safety and effectiveness of Motiva SmoothSilk® silicone gel filled breast implants submitted to the FDA. The reported data includes both the Primary and Revision Breast Augmentation cohorts.</p><p><strong>Methods: </strong>The five-year clinical data from the breast augmentation cohorts of the Motiva IDE, 10-year pivotal study was submitted to the FDA in 2024. Data was collected from on adverse events, reoperation, patient and physician satisfaction, connective tissue and rheumatologic diseases, and quality of life instruments. MRIs were obtained at years 1, 2, 3, and 5 for patients enrolled in the MRI sub-study.</p><p><strong>Results: </strong>There were 451 primary augmentation patients and 109 revision augmentation patients enrolled in the pivotal study. Follow-up rates were 87% of expected patients at both years 4 and 5. Of the 218 patients enrolled in the MRI cohort, 152 underwent MRI screening at year 5, an overall compliance of 79.2% of expected screenings. The reported re-operation rates for any reason were 8.8% in the Primary Augmentation Cohort and 36.0% in the Revision Augmentation Cohort.</p><p><strong>Conclusions: </strong>The five-year data from the Primary and Revision Breast Augmentation cohorts reveal low rates of device rupture. Size change and malposition were the most common causes of reoperation in the Primary Augmentation Cohort, while capsular contracture and size change were the leading drivers of reoperation in the Revision Augmentation Cohort.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145562128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Autologous Fat Grafting: A Systematic Review of Enhancement Strategies and Graft Survival. 优化自体脂肪移植:增强策略和移植物存活的系统综述。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-19 DOI: 10.1093/asj/sjaf242
Sophie Hasiba-Pappas, Elisa Opriessnig, Sebastian P Nischwitz, Raimund Winter, Patrick Mandal, Martina Carnieletto, Lars-Peter Kamolz, Hanna Luze

Autologous fat grafting has become an important tool in reconstructive and aesthetic surgery, particularly for breast reconstruction and soft tissue augmentation. Despite its promise, long-term outcomes remain unpredictable. To address this, research has increasingly focused on optimizing graft survival by enriching the lipoaspirate with additional substances. A systematic search of PubMed and Web of Science identified studies on enhancement methods of autologous fat grafting in both animal models and clinical settings, published up to February 2025. In vitro trials, case reports, and studies comparing techniques without specific enhancement of the lipoaspirate were excluded. Twenty-seven studies fulfilled the criteria, including 15 animal studies and 12 clinical studies, most of which investigated applications in breast reconstruction and augmentation. The included studies showed substantial heterogeneity in enhancement strategies, case numbers, follow-up duration, and outcome measures. The most frequently examined approaches involved enrichment with stromal vascular fraction (SVF) and/or adipose-derived stem cells (ADSCs). Both methods demonstrated favorable results in many trials, though statistical significance was not always achieved. Other strategies included the use of Vitamin D3, Botulinum toxin A, platelet-rich plasma (PRP), and less frequently studied agents such as N-acetylcysteine and Salvia miltiorrhiza. Overall, enrichment of lipoaspirate appears to enhance graft survival, with SVF/ADSC-based methods and PRP emerging as the most promising approaches. Nevertheless, marked variability in protocols and outcome measures hampers comparability between studies. Larger randomized controlled trials employing standardized methodologies are essential to confirm clinical feasibility and provide a basis for evidence-based guidelines.

自体脂肪移植已成为整形外科的重要手段,尤其是乳房再造和软组织隆胸手术。尽管前景看好,但长期结果仍难以预测。为了解决这一问题,研究越来越多地关注通过在抽脂液中添加额外物质来优化移植物存活。通过对PubMed和Web of Science的系统搜索,发现了截至2025年2月发表的关于动物模型和临床环境中自体脂肪移植增强方法的研究。体外试验、病例报告和没有特异性增强抽脂剂的比较技术的研究被排除在外。27项研究符合标准,包括15项动物研究和12项临床研究,其中大部分研究在乳房重建和隆胸中的应用。纳入的研究显示在强化策略、病例数、随访时间和结果测量方面存在很大的异质性。最常用的方法包括基质血管部分(SVF)和/或脂肪来源干细胞(ADSCs)富集。这两种方法在许多试验中都显示出良好的结果,尽管并不总是达到统计学意义。其他策略包括使用维生素D3、肉毒杆菌毒素A、富血小板血浆(PRP)和较少研究的药物,如n -乙酰半胱氨酸和丹参。总的来说,抽脂液的富集似乎可以提高移植物的存活率,基于SVF/ adsc的方法和PRP是最有前途的方法。然而,方案和结果测量的显著差异阻碍了研究之间的可比性。采用标准化方法的大型随机对照试验对于确认临床可行性和为循证指南提供基础至关重要。
{"title":"Optimizing Autologous Fat Grafting: A Systematic Review of Enhancement Strategies and Graft Survival.","authors":"Sophie Hasiba-Pappas, Elisa Opriessnig, Sebastian P Nischwitz, Raimund Winter, Patrick Mandal, Martina Carnieletto, Lars-Peter Kamolz, Hanna Luze","doi":"10.1093/asj/sjaf242","DOIUrl":"https://doi.org/10.1093/asj/sjaf242","url":null,"abstract":"<p><p>Autologous fat grafting has become an important tool in reconstructive and aesthetic surgery, particularly for breast reconstruction and soft tissue augmentation. Despite its promise, long-term outcomes remain unpredictable. To address this, research has increasingly focused on optimizing graft survival by enriching the lipoaspirate with additional substances. A systematic search of PubMed and Web of Science identified studies on enhancement methods of autologous fat grafting in both animal models and clinical settings, published up to February 2025. In vitro trials, case reports, and studies comparing techniques without specific enhancement of the lipoaspirate were excluded. Twenty-seven studies fulfilled the criteria, including 15 animal studies and 12 clinical studies, most of which investigated applications in breast reconstruction and augmentation. The included studies showed substantial heterogeneity in enhancement strategies, case numbers, follow-up duration, and outcome measures. The most frequently examined approaches involved enrichment with stromal vascular fraction (SVF) and/or adipose-derived stem cells (ADSCs). Both methods demonstrated favorable results in many trials, though statistical significance was not always achieved. Other strategies included the use of Vitamin D3, Botulinum toxin A, platelet-rich plasma (PRP), and less frequently studied agents such as N-acetylcysteine and Salvia miltiorrhiza. Overall, enrichment of lipoaspirate appears to enhance graft survival, with SVF/ADSC-based methods and PRP emerging as the most promising approaches. Nevertheless, marked variability in protocols and outcome measures hampers comparability between studies. Larger randomized controlled trials employing standardized methodologies are essential to confirm clinical feasibility and provide a basis for evidence-based guidelines.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145556155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological Scoring Improves the Correlation Between Capsular Contracture Diagnosis and Patient-Reported Outcomes. 组织病理学评分提高了包膜挛缩诊断与患者报告结果之间的相关性。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-18 DOI: 10.1093/asj/sjaf241
Maria O Snog, Tim K Weltz, Mads G Jørgensen, Erik E F Bak, Linda R Gudjonsdottir, Mathilde N Hemmingsen, Andreas Larsen, Jens Jørgen Elberg, Jesper Trillingsgaard, Lisbet R Hölmich, Nicco Krezdorn, Peter Vester-Glowinski, Mathias Ørholt, Mikkel Herly

Background: The Baker classification is used to grade capsular contracture after breast-implant surgery, yet its correlation with patient-reported outcomes is poor.

Objectives: To determine whether histopathological verification of capsular contracture status strengthens the association between Baker grade and BREAST-Q scores.

Methods: Women scheduled for implant exchange or removal completed the BREAST-Q "Physical Well-Being-Chest" module. Raw BREAST-Q sum scores were transformed to a 0-100 scale, where higher scores indicate increased comfort. The attending surgeon classified breasts using the Baker scale (I-IV). Capsule biopsies were scored with a validated histopathological scoring system;Baker grades were deemed "confirmed" when histology and Baker grade were aligned and otherwise deemed "misclassified". Linear regressions compared the relationship between BREAST-Q scores and Baker grade in confirmed versus misclassified cases.

Results: A total of 103 patients (58 augmentation, 45 reconstruction) were included. The Baker classification was confirmed histologically in 53/58 augmentation patients (91%), and 36/45 reconstruction patients (80%). In confirmed augmentation cases, each one-grade increase in Baker significantly worsened chest well-being by -8.80 BREAST-Q points (95% CI [-14.42, -3.18]; P=.003). No correlation was found in the misclassified augmentation cases (-3.21 points; P=.57), confirmed reconstruction cases (-5.00 points; P=.19), or in the misclassified reconstruction cases (-5.72 points; P=.54).

Conclusions: Histologically confirmed Baker classification correlates significantly with chest well-being assessed with BREAST-Q for the patients with breast augmentation, whereas no such correlation was observed in cases where the histology and Baker classification showed a mismatch. This suggests that histopathological scoring can increase diagnostic accuracy when assessing capsular contracture status.

背景:Baker分类法用于对乳房植入手术后的包膜挛缩进行分级,但其与患者报告的预后相关性较差。目的:确定包膜挛缩状态的组织病理学验证是否加强了Baker分级和BREAST-Q评分之间的关联。方法:计划植入物置换或移除的女性完成BREAST-Q“身体健康-胸部”模块。原始的BREAST-Q总和得分转化为0-100分,分数越高表明舒适度越高。主治医生使用贝克评分(I-IV)对乳房进行分类。采用经过验证的组织病理学评分系统对胶囊活检进行评分;当组织学和贝克等级一致时,贝克等级被视为“确认”,否则被视为“错误分类”。线性回归比较确诊病例和误诊病例中BREAST-Q评分和贝克评分之间的关系。结果:共纳入103例患者,其中隆胸58例,重建45例。在53/58例隆胸患者(91%)和36/45例重建患者(80%)中组织学证实了Baker分类。在确诊的隆胸病例中,Baker每增加一级,胸部健康状况显著恶化-8.80 BREAST-Q点(95% CI [-14.42, -3.18]; P= 0.003)。错误分类的增强病例(-3.21分,P= 0.57)、确定的重建病例(-5.00分,P= 0.19)、错误分类的重建病例(-5.72分,P= 0.54)无相关性。结论:组织学证实的贝克分类与隆胸患者的胸部健康状况显著相关,而在组织学和贝克分类不匹配的情况下,没有观察到这种相关性。这表明,在评估包膜挛缩状态时,组织病理学评分可以提高诊断的准确性。
{"title":"Histopathological Scoring Improves the Correlation Between Capsular Contracture Diagnosis and Patient-Reported Outcomes.","authors":"Maria O Snog, Tim K Weltz, Mads G Jørgensen, Erik E F Bak, Linda R Gudjonsdottir, Mathilde N Hemmingsen, Andreas Larsen, Jens Jørgen Elberg, Jesper Trillingsgaard, Lisbet R Hölmich, Nicco Krezdorn, Peter Vester-Glowinski, Mathias Ørholt, Mikkel Herly","doi":"10.1093/asj/sjaf241","DOIUrl":"https://doi.org/10.1093/asj/sjaf241","url":null,"abstract":"<p><strong>Background: </strong>The Baker classification is used to grade capsular contracture after breast-implant surgery, yet its correlation with patient-reported outcomes is poor.</p><p><strong>Objectives: </strong>To determine whether histopathological verification of capsular contracture status strengthens the association between Baker grade and BREAST-Q scores.</p><p><strong>Methods: </strong>Women scheduled for implant exchange or removal completed the BREAST-Q \"Physical Well-Being-Chest\" module. Raw BREAST-Q sum scores were transformed to a 0-100 scale, where higher scores indicate increased comfort. The attending surgeon classified breasts using the Baker scale (I-IV). Capsule biopsies were scored with a validated histopathological scoring system;Baker grades were deemed \"confirmed\" when histology and Baker grade were aligned and otherwise deemed \"misclassified\". Linear regressions compared the relationship between BREAST-Q scores and Baker grade in confirmed versus misclassified cases.</p><p><strong>Results: </strong>A total of 103 patients (58 augmentation, 45 reconstruction) were included. The Baker classification was confirmed histologically in 53/58 augmentation patients (91%), and 36/45 reconstruction patients (80%). In confirmed augmentation cases, each one-grade increase in Baker significantly worsened chest well-being by -8.80 BREAST-Q points (95% CI [-14.42, -3.18]; P=.003). No correlation was found in the misclassified augmentation cases (-3.21 points; P=.57), confirmed reconstruction cases (-5.00 points; P=.19), or in the misclassified reconstruction cases (-5.72 points; P=.54).</p><p><strong>Conclusions: </strong>Histologically confirmed Baker classification correlates significantly with chest well-being assessed with BREAST-Q for the patients with breast augmentation, whereas no such correlation was observed in cases where the histology and Baker classification showed a mismatch. This suggests that histopathological scoring can increase diagnostic accuracy when assessing capsular contracture status.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145538204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central Platform Surgery for Large and Deviated Noses -The Libra Flap: Low Septal Strip Dorsal Y Preservation. 大鼻偏鼻中央平台手术-天秤座皮瓣:低鼻中隔条状Y背侧保留。
IF 3 2区 医学 Q1 SURGERY Pub Date : 2025-11-18 DOI: 10.1093/asj/sjaf235
Barış Cakir, Erhan Coşkun, Bülent Genç, Tayfun Aköz, Paul D Durand, Charles Anthony East

Background: Traditionally, dorsal reconstruction is required after osseocartilagenous resection in patients with large noses where the cartilaginous dorsum is overdeveloped and wide, rendering it impossible for preservation. We aim to reduce the need for dorsal reconstruction by changing the resection technique in such noses.

Objectives: The present article describes and evaluates a technique, which consists of an anatomic resection of the nasal dorsum that we propose to be used in those patients who fall in the grey zone between requiring traditional DP and structural techniques. Dorsal Y preservation pre-cuts the intended dorsal aesthetic lines defining a central platform that can be flexed, lowered or moved laterally.

Methods: A total of 77 patients who underwent low septal strip dorsal Y preservation by two different surgeons were studied retrospectively.

Results: Of the total patients, 85.7% (66) were female and 14.3% (11) were male. A closed approach was used in all cases. The patients were followed up from 6-36 months with a median follow up of 13 months.

Conclusions: The central platform (Libra flap) technique provides anatomical results in patients with large, wide noses and an axis deviation. For those cases with other challenges, dorsal preservation and structure techniques should remain as preferred treatment modalities.

背景:传统上,对于大鼻患者,由于软骨背过于发达和宽阔,无法保存,需要在骨软骨切除术后进行背侧重建。我们的目标是通过改变鼻的切除技术来减少对背侧重建的需要。目的:本文描述并评估了一种技术,该技术由鼻背解剖切除术组成,我们建议用于那些处于需要传统DP和结构技术之间灰色地带的患者。背侧Y型保护预先切割了预定的背侧美学线条,定义了一个可以弯曲、降低或横向移动的中心平台。方法:回顾性分析77例经不同术式行低间隔条Y背侧保留术的患者。结果:女性66例,占85.7%;男性11例,占14.3%。所有病例均采用封闭入路。随访6 ~ 36个月,中位随访13个月。结论:中心平台(天秤座皮瓣)技术对鼻梁偏大、鼻梁偏宽的患者具有良好的解剖效果。对于那些有其他挑战的病例,背侧保护和结构技术仍应作为首选的治疗方式。
{"title":"Central Platform Surgery for Large and Deviated Noses -The Libra Flap: Low Septal Strip Dorsal Y Preservation.","authors":"Barış Cakir, Erhan Coşkun, Bülent Genç, Tayfun Aköz, Paul D Durand, Charles Anthony East","doi":"10.1093/asj/sjaf235","DOIUrl":"https://doi.org/10.1093/asj/sjaf235","url":null,"abstract":"<p><strong>Background: </strong>Traditionally, dorsal reconstruction is required after osseocartilagenous resection in patients with large noses where the cartilaginous dorsum is overdeveloped and wide, rendering it impossible for preservation. We aim to reduce the need for dorsal reconstruction by changing the resection technique in such noses.</p><p><strong>Objectives: </strong>The present article describes and evaluates a technique, which consists of an anatomic resection of the nasal dorsum that we propose to be used in those patients who fall in the grey zone between requiring traditional DP and structural techniques. Dorsal Y preservation pre-cuts the intended dorsal aesthetic lines defining a central platform that can be flexed, lowered or moved laterally.</p><p><strong>Methods: </strong>A total of 77 patients who underwent low septal strip dorsal Y preservation by two different surgeons were studied retrospectively.</p><p><strong>Results: </strong>Of the total patients, 85.7% (66) were female and 14.3% (11) were male. A closed approach was used in all cases. The patients were followed up from 6-36 months with a median follow up of 13 months.</p><p><strong>Conclusions: </strong>The central platform (Libra flap) technique provides anatomical results in patients with large, wide noses and an axis deviation. For those cases with other challenges, dorsal preservation and structure techniques should remain as preferred treatment modalities.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145538125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Aesthetic Surgery Journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1