Background: Breast ptosis remains challenging, particularly when excess skin and parenchyma are pronounced. Inferior-pedicle techniques may be prone to recurrent ptosis with lower-pole elongation and loss of upper-pole projection.
Objectives: To describe and evaluate a mastopexy technique using an inferior-septal pedicle with dermal-muscular fixation designed to enhance long-term stability in severe ptosis (Regnault grade III).
Methods: Single-surgeon, single-center consecutive case series (level IV). One hundred sixteen women with grade III ptosis underwent surgery from January 2016 to June 2023. The technique uses an inferior-septal dermoglandular pedicle with dermal fixation to the pectoralis major. Outcomes were assessed via standardized examinations, photography, and the BREAST-Q Reduction/Mastopexy module at 3, 6, and 12 months.
Results: A total of 116 patients were analyzed (median follow-up, 12 months). Mean SN-N distance decreased from 36.3 to 22.0 cm, and N-IMF from 14.5 to 8.0 cm at 12 months. BREAST-Q scores at 12 months demonstrated high satisfaction (mean ≥80/100). No NAC-related vascular events, infections, or hematomas occurred (0%). Wound-healing disturbances were noted in 16/232 breasts (6.9%). Revisions occurred in 13/116 patients (11.2%), mainly scar adjustments; secondary ptosis correction was required in 5/116 (4.3%). No cases of persistent nipple sensory loss were observed.
Conclusions: The proposed mastopexy technique with inferior-septal pedicle provides effective correction of severe ptosis with good upper-pole fullness and stable long-term breast shape, while preserving NAC perfusion, innervation, and potential lactational function.
{"title":"Mastopexy With Inferior-septal Pedicle and Dermal Fixation: A Modification to Improve Aesthetic Stability.","authors":"Maksim Barsakov, Natalia Korableva","doi":"10.1093/asj/sjag010","DOIUrl":"https://doi.org/10.1093/asj/sjag010","url":null,"abstract":"<p><strong>Background: </strong>Breast ptosis remains challenging, particularly when excess skin and parenchyma are pronounced. Inferior-pedicle techniques may be prone to recurrent ptosis with lower-pole elongation and loss of upper-pole projection.</p><p><strong>Objectives: </strong>To describe and evaluate a mastopexy technique using an inferior-septal pedicle with dermal-muscular fixation designed to enhance long-term stability in severe ptosis (Regnault grade III).</p><p><strong>Methods: </strong>Single-surgeon, single-center consecutive case series (level IV). One hundred sixteen women with grade III ptosis underwent surgery from January 2016 to June 2023. The technique uses an inferior-septal dermoglandular pedicle with dermal fixation to the pectoralis major. Outcomes were assessed via standardized examinations, photography, and the BREAST-Q Reduction/Mastopexy module at 3, 6, and 12 months.</p><p><strong>Results: </strong>A total of 116 patients were analyzed (median follow-up, 12 months). Mean SN-N distance decreased from 36.3 to 22.0 cm, and N-IMF from 14.5 to 8.0 cm at 12 months. BREAST-Q scores at 12 months demonstrated high satisfaction (mean ≥80/100). No NAC-related vascular events, infections, or hematomas occurred (0%). Wound-healing disturbances were noted in 16/232 breasts (6.9%). Revisions occurred in 13/116 patients (11.2%), mainly scar adjustments; secondary ptosis correction was required in 5/116 (4.3%). No cases of persistent nipple sensory loss were observed.</p><p><strong>Conclusions: </strong>The proposed mastopexy technique with inferior-septal pedicle provides effective correction of severe ptosis with good upper-pole fullness and stable long-term breast shape, while preserving NAC perfusion, innervation, and potential lactational function.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raisa Chowdhury, Nisreen Al-Musaileem, Islam Alzayadneh, Aseel Doubi, Karanvir S Raman, Philip Solomon, Richard Rival
Background: Postoperative nasal obstruction and asymmetry can compromise satisfaction after rhinoplasty. Internal nasal dilators (INDs) may support early healing by maintaining valve patency and symmetry, but their postoperative efficacy has not been systematically evaluated.
Objectives: To determine whether IND use after septorhinoplasty improves functional, aesthetic, and symmetry outcomes compared with standard care.
Methods: In this single-center, randomized, single-blinded trial, 128 adults undergoing primary septorhinoplasty were allocated (1:1) to IND plus standard care or standard care alone. Assessments were performed at baseline, 3 months, and 12 months using the validated Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) and a nostril-symmetry item (0 = perfect, 4 = very asymmetrical). The primary outcome was patient-reported nostril symmetry; secondary outcomes included functional and aesthetic SCHNOS scores, comfort, and adverse events.
Results: Baseline characteristics were comparable. Nostril symmetry scores favored the IND group at 3 months (0.78 ± 0.92 vs 1.42 ± 1.09; p = .001) and 12 months (0.46 ± 0.71 vs 1.40 ± 1.20; p < .001). Functional SCHNOS improved in both groups, with a slightly greater gain in the IND group at 12 months (+10.2 ± 4.1 vs +7.9 ± 4.4; p = .048). Aesthetic SCHNOS scores improved similarly across groups (p = .73). Device comfort was high (VAS 8.1 ± 1.4/10), and no device-related complications occurred.
Conclusions: Internal nasal dilators improved postoperative nostril symmetry and maintained favorable functional and aesthetic outcomes without added risk or discomfort. These findings support the adjunctive use of INDs to enhance symmetry and patient satisfaction after rhinoplasty.
背景:术后鼻塞和不对称会影响鼻整形术后的满意度。内鼻扩张器(INDs)可以通过维持瓣膜的开放和对称来支持早期愈合,但其术后疗效尚未得到系统的评估。目的:确定与标准护理相比,鼻中隔成形术后使用IND是否能改善功能、美学和对称性。方法:在这项单中心、随机、单盲试验中,128名接受初级鼻中隔成形术的成年人(1:1)被分配到IND加标准治疗或单独标准治疗组。在基线、3个月和12个月进行评估,使用经过验证的标准化美容和健康鼻部结果调查(SCHNOS)和鼻孔对称项目(0 =完美,4 =非常不对称)。主要结局是患者报告的鼻孔对称;次要结局包括功能和美学SCHNOS评分、舒适度和不良事件。结果:基线特征可比较。鼻孔对称评分在3个月(0.78±0.92 vs 1.42±1.09,p = 0.001)和12个月(0.46±0.71 vs 1.40±1.20,p < 0.001)时优于IND组。两组的功能性SCHNOS均有改善,IND组在12个月时的增加略大(+10.2±4.1 vs +7.9±4.4;p = 0.048)。美学SCHNOS评分在各组间的改善相似(p = 0.73)。器械舒适度高(VAS 8.1±1.4/10),无器械相关并发症发生。结论:内扩鼻器改善了术后鼻孔的对称性,并保持了良好的功能和美观效果,没有增加风险或不适。这些发现支持辅助使用INDs来增强鼻整形术后的对称性和患者满意度。
{"title":"Internal Nasal Dilators After Septorhinoplasty: A Randomized Controlled Trial of Functional and Aesthetic Outcomes.","authors":"Raisa Chowdhury, Nisreen Al-Musaileem, Islam Alzayadneh, Aseel Doubi, Karanvir S Raman, Philip Solomon, Richard Rival","doi":"10.1093/asj/sjag007","DOIUrl":"https://doi.org/10.1093/asj/sjag007","url":null,"abstract":"<p><strong>Background: </strong>Postoperative nasal obstruction and asymmetry can compromise satisfaction after rhinoplasty. Internal nasal dilators (INDs) may support early healing by maintaining valve patency and symmetry, but their postoperative efficacy has not been systematically evaluated.</p><p><strong>Objectives: </strong>To determine whether IND use after septorhinoplasty improves functional, aesthetic, and symmetry outcomes compared with standard care.</p><p><strong>Methods: </strong>In this single-center, randomized, single-blinded trial, 128 adults undergoing primary septorhinoplasty were allocated (1:1) to IND plus standard care or standard care alone. Assessments were performed at baseline, 3 months, and 12 months using the validated Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) and a nostril-symmetry item (0 = perfect, 4 = very asymmetrical). The primary outcome was patient-reported nostril symmetry; secondary outcomes included functional and aesthetic SCHNOS scores, comfort, and adverse events.</p><p><strong>Results: </strong>Baseline characteristics were comparable. Nostril symmetry scores favored the IND group at 3 months (0.78 ± 0.92 vs 1.42 ± 1.09; p = .001) and 12 months (0.46 ± 0.71 vs 1.40 ± 1.20; p < .001). Functional SCHNOS improved in both groups, with a slightly greater gain in the IND group at 12 months (+10.2 ± 4.1 vs +7.9 ± 4.4; p = .048). Aesthetic SCHNOS scores improved similarly across groups (p = .73). Device comfort was high (VAS 8.1 ± 1.4/10), and no device-related complications occurred.</p><p><strong>Conclusions: </strong>Internal nasal dilators improved postoperative nostril symmetry and maintained favorable functional and aesthetic outcomes without added risk or discomfort. These findings support the adjunctive use of INDs to enhance symmetry and patient satisfaction after rhinoplasty.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145997174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Albert Brotgandel, Sarah Moffitt, Carson Bair, Claudia Cruz, Joshua Scarcella, Meredith Moore, Paul Smith
Social media has become a powerful tool in plastic surgery, offering opportunities to attract patients and share content. However, its use raises medicolegal challenges, including privacy, defamation, and professional boundaries. The impact of social media on lawsuits involving plastic surgeons remains underexplored. A systematic review of publicly available legal cases was conducted using WestLaw and Nexis Uni databases, covering January 2007 - January 2024. 135 unique cases were screened by three independent reviewers. Inclusion required involvement of social media and plastic surgeons or practices. Twenty-seven cases met criteria and were analyzed for plaintiff/defendant status, cause of action, use of anti-SLAPP statutes, and case outcomes. Of the 27 included cases, 17 were filed by plastic surgeons, seven by patients, two by practices, and one by a non-patient. Defamation was the most common claim (15/27). Plastic surgeons and patients were equally represented as defendants. Only three defamation cases resulted in court rulings favoring the plaintiff, and one case was settled in arbitration. Additional claims included invasion of privacy, copyright infringement, trademark violation, and misappropriation of likeness. Cases highlighted risks associated with improper handling of patient photographs and employee-managed accounts. Plastic surgeons face growing medicolegal exposure related to social media. Defamation lawsuits against patients rarely succeed. Surgeons should avoid litigation as a primary strategy and instead mitigate risk through clear policies, professional conduct, and strong physician-patient communication. Proactive reputation management and adherence to ethical standards remain the most effective tools to reduce litigation in the social media era.
{"title":"A Systematic Review of Medicolegal Social Media Related Issues in Plastic Surgery.","authors":"Albert Brotgandel, Sarah Moffitt, Carson Bair, Claudia Cruz, Joshua Scarcella, Meredith Moore, Paul Smith","doi":"10.1093/asj/sjag008","DOIUrl":"https://doi.org/10.1093/asj/sjag008","url":null,"abstract":"<p><p>Social media has become a powerful tool in plastic surgery, offering opportunities to attract patients and share content. However, its use raises medicolegal challenges, including privacy, defamation, and professional boundaries. The impact of social media on lawsuits involving plastic surgeons remains underexplored. A systematic review of publicly available legal cases was conducted using WestLaw and Nexis Uni databases, covering January 2007 - January 2024. 135 unique cases were screened by three independent reviewers. Inclusion required involvement of social media and plastic surgeons or practices. Twenty-seven cases met criteria and were analyzed for plaintiff/defendant status, cause of action, use of anti-SLAPP statutes, and case outcomes. Of the 27 included cases, 17 were filed by plastic surgeons, seven by patients, two by practices, and one by a non-patient. Defamation was the most common claim (15/27). Plastic surgeons and patients were equally represented as defendants. Only three defamation cases resulted in court rulings favoring the plaintiff, and one case was settled in arbitration. Additional claims included invasion of privacy, copyright infringement, trademark violation, and misappropriation of likeness. Cases highlighted risks associated with improper handling of patient photographs and employee-managed accounts. Plastic surgeons face growing medicolegal exposure related to social media. Defamation lawsuits against patients rarely succeed. Surgeons should avoid litigation as a primary strategy and instead mitigate risk through clear policies, professional conduct, and strong physician-patient communication. Proactive reputation management and adherence to ethical standards remain the most effective tools to reduce litigation in the social media era.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145997111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: For gender-affirming mastectomy in patients with gender dysphoria and small/non-ptotic breasts, traditional periareolar techniques carry risks of visible scar complications. A scar-minimizing alternative is needed.
Objectives: To evaluate the outcomes of a novel non-endoscopic axillary approach mastectomy, aiming to eliminate areolar scars or diminish circumareolar incision while assessing safety and patient satisfaction.
Methods: This study included patients classified with Fisher 1, 2a, and a portion of 2b patients. Mastectomy was performed via an axillary incision without endoscopic assistance. Outcomes were evaluated through complication rates and patient-reported outcomes using the BODY-Q questionnaire (score 0-100).
Results: From December 2020 to August 2024, 48 patients (average age 33.65) underwent the procedure. The average operative time was 167.1 minutes. The overall complication rate was 45.8% (22/48), predominantly minor, reversible nipple-areola superficial skin necrosis (20.8%). Severe complications were rare: total NAC necrosis 2.0% (1/48) and acute hematoma 2.0% (1/48). Patient satisfaction on the BODY-Q scale was statistically very high.
Conclusions: This axillary approach for mastectomy successfully prioritizes minimal scarring, a key aesthetic concern particularly for East Asian patients. In a carefully selected cohort, it achieves high patient satisfaction with a low rate of severe complications, offering a valuable surgical alternative.
{"title":"Axillary Approach Non-Skin-Excisional Mastectomy Without Endoscopic Assistance in Chest Masculinization Surgery.","authors":"Xin Tang","doi":"10.1093/asj/sjag009","DOIUrl":"https://doi.org/10.1093/asj/sjag009","url":null,"abstract":"<p><strong>Background: </strong>For gender-affirming mastectomy in patients with gender dysphoria and small/non-ptotic breasts, traditional periareolar techniques carry risks of visible scar complications. A scar-minimizing alternative is needed.</p><p><strong>Objectives: </strong>To evaluate the outcomes of a novel non-endoscopic axillary approach mastectomy, aiming to eliminate areolar scars or diminish circumareolar incision while assessing safety and patient satisfaction.</p><p><strong>Methods: </strong>This study included patients classified with Fisher 1, 2a, and a portion of 2b patients. Mastectomy was performed via an axillary incision without endoscopic assistance. Outcomes were evaluated through complication rates and patient-reported outcomes using the BODY-Q questionnaire (score 0-100).</p><p><strong>Results: </strong>From December 2020 to August 2024, 48 patients (average age 33.65) underwent the procedure. The average operative time was 167.1 minutes. The overall complication rate was 45.8% (22/48), predominantly minor, reversible nipple-areola superficial skin necrosis (20.8%). Severe complications were rare: total NAC necrosis 2.0% (1/48) and acute hematoma 2.0% (1/48). Patient satisfaction on the BODY-Q scale was statistically very high.</p><p><strong>Conclusions: </strong>This axillary approach for mastectomy successfully prioritizes minimal scarring, a key aesthetic concern particularly for East Asian patients. In a carefully selected cohort, it achieves high patient satisfaction with a low rate of severe complications, offering a valuable surgical alternative.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145997169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The efficacy and safety of botulinum toxin type A (BoNTA) treatment for primary axillary hyperhidrosis (PAH) have not been explored in the Chinese population.
Objectives: The objective was to evaluate efficacy and safety of 1 intradermal BoNTA injection in Chinese PAH cases.
Methods: This was a Phase 3, multicenter, randomized, double-blind, placebo-controlled study. Patients were randomized to an experimental group or the control group at a ratio of 3:1 and received either BoNTA or a placebo once. The primary efficacy endpoint was the proportion of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment compared to baseline. The key secondary efficacy endpoints were the percentage changes in axillary sweat weight at Weeks 1, 4, 8, and 16 posttreatment.
Results: A total of 344 patients were randomized to the experimental group (n = 258) or the control group (n = 86). The proportions of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment were 83.72% (216/258) in the experimental group and 55.81% (48/86) in the control group, respectively. The between-group difference was 27.91% (P < .001). BoNTA treatment yielded a significant reduction in axillary sweat weight, hyperhidrotic area, hyperhidrosis disease severity scale (HDSS) scores, and grade of bromhidrosis. The patients in the experimental group reported significantly higher satisfaction scores than those in the control group. BoNTA treatment was well tolerated. Neither group experienced suspected unexpected serious adverse reactions, or adverse events or adverse drug reactions leading to withdrawal or death.
Conclusions: One intradermal 50-U BoNTA treatment led to a significant reduction in axillary sweat weight, axillary hyperhidrotic area, HDSS scores, and axillary bromhidrosis grades in Chinese PAH patients. The therapeutic effect was maintained for 16 weeks posttreatment, with a favorable safety profile.
{"title":"Botulinum Toxin Type A in the Treatment of Primary Axillary Hyperhidrosis:A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety in Chinese Patients.","authors":"Yiming Li, Baogang Sun, Jianyun Lu, Wei Lai, Huiping Wang, Qiuning Sun, Baoxi Wang, Yanyan Feng, Junfeng He, Yubao Huang, Yunkai Yang, Chengjun Zhang, Li Li","doi":"10.1093/asj/sjaf260","DOIUrl":"https://doi.org/10.1093/asj/sjaf260","url":null,"abstract":"<p><strong>Background: </strong>The efficacy and safety of botulinum toxin type A (BoNTA) treatment for primary axillary hyperhidrosis (PAH) have not been explored in the Chinese population.</p><p><strong>Objectives: </strong>The objective was to evaluate efficacy and safety of 1 intradermal BoNTA injection in Chinese PAH cases.</p><p><strong>Methods: </strong>This was a Phase 3, multicenter, randomized, double-blind, placebo-controlled study. Patients were randomized to an experimental group or the control group at a ratio of 3:1 and received either BoNTA or a placebo once. The primary efficacy endpoint was the proportion of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment compared to baseline. The key secondary efficacy endpoints were the percentage changes in axillary sweat weight at Weeks 1, 4, 8, and 16 posttreatment.</p><p><strong>Results: </strong>A total of 344 patients were randomized to the experimental group (n = 258) or the control group (n = 86). The proportions of patients who experienced an over 50% reduction in axillary sweat weight at Week 4 posttreatment were 83.72% (216/258) in the experimental group and 55.81% (48/86) in the control group, respectively. The between-group difference was 27.91% (P < .001). BoNTA treatment yielded a significant reduction in axillary sweat weight, hyperhidrotic area, hyperhidrosis disease severity scale (HDSS) scores, and grade of bromhidrosis. The patients in the experimental group reported significantly higher satisfaction scores than those in the control group. BoNTA treatment was well tolerated. Neither group experienced suspected unexpected serious adverse reactions, or adverse events or adverse drug reactions leading to withdrawal or death.</p><p><strong>Conclusions: </strong>One intradermal 50-U BoNTA treatment led to a significant reduction in axillary sweat weight, axillary hyperhidrotic area, HDSS scores, and axillary bromhidrosis grades in Chinese PAH patients. The therapeutic effect was maintained for 16 weeks posttreatment, with a favorable safety profile.</p><p><strong>Level of evidence: 1 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146002856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan Cvelbar, R'ay Fodor, Elad Fraiman, Bahman Guyuron
Background: Nearly two thirds of patients who suffer from migraine headaches (MH) have a rhinogenic trigger site. A majority of rhinoplasty patients are female, and an estimated 18% of females suffer from MH. Rhinogenic MH and sinus headaches (SH) are commonly triggered by elements which can be readily addressed during septorhinoplasty. Consequently, this surgery may present a dual opportunity to address MH/SH and cosmetic concerns simultaneously.
Objectives: This study aims to quantify the incidence of MH and SH in patients presenting for primary rhinoplasty.
Methods: A retrospective review was conducted on a consecutive sample of patients who presented for primary rhinoplasty. The senior author's 2-page preoperative questionnaire which inquires about MH and SH was used to identify patients who self-reported MH and SH. MH and SH incidences were calculated as a percentage of the total number of patient responses.
Results: A total of 190 primary rhinoplasty patients (164 females (86.32%) and 26 males (13.68%)) were included in this study. In total, 64 (33.68%) had either SH or MH. Twenty-nine patients (15.26%) had SH only, 12 (6.32%) MH only, 23 (12.11%) both MH and SH, and 35 (18.42%) had MH with or without SH.
Conclusions: MH incidence (18.42%) in this patient sample was greater than the reported global migraine rate of 14-15%. By screening for and treating rhinogenic MH and SH, surgeons can both alleviate symptoms while fulfilling aesthetic objectives.
{"title":"Frequency of Migraine and Sinus Headaches in Patients Undergoing Primary Rhinoplasty.","authors":"Ryan Cvelbar, R'ay Fodor, Elad Fraiman, Bahman Guyuron","doi":"10.1093/asj/sjag006","DOIUrl":"https://doi.org/10.1093/asj/sjag006","url":null,"abstract":"<p><strong>Background: </strong>Nearly two thirds of patients who suffer from migraine headaches (MH) have a rhinogenic trigger site. A majority of rhinoplasty patients are female, and an estimated 18% of females suffer from MH. Rhinogenic MH and sinus headaches (SH) are commonly triggered by elements which can be readily addressed during septorhinoplasty. Consequently, this surgery may present a dual opportunity to address MH/SH and cosmetic concerns simultaneously.</p><p><strong>Objectives: </strong>This study aims to quantify the incidence of MH and SH in patients presenting for primary rhinoplasty.</p><p><strong>Methods: </strong>A retrospective review was conducted on a consecutive sample of patients who presented for primary rhinoplasty. The senior author's 2-page preoperative questionnaire which inquires about MH and SH was used to identify patients who self-reported MH and SH. MH and SH incidences were calculated as a percentage of the total number of patient responses.</p><p><strong>Results: </strong>A total of 190 primary rhinoplasty patients (164 females (86.32%) and 26 males (13.68%)) were included in this study. In total, 64 (33.68%) had either SH or MH. Twenty-nine patients (15.26%) had SH only, 12 (6.32%) MH only, 23 (12.11%) both MH and SH, and 35 (18.42%) had MH with or without SH.</p><p><strong>Conclusions: </strong>MH incidence (18.42%) in this patient sample was greater than the reported global migraine rate of 14-15%. By screening for and treating rhinogenic MH and SH, surgeons can both alleviate symptoms while fulfilling aesthetic objectives.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145987926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on: Research Requirements for Residency Applicants Need to be Reconsidered.","authors":"Andrew Y Zhang","doi":"10.1093/asj/sjag004","DOIUrl":"https://doi.org/10.1093/asj/sjag004","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Hyaluronic acid (HA) dermal fillers are widely used as a non-surgical treatment for facial aging, including nasolabial folds (NLFs). As demand for convenient aesthetic procedures increases, new HA products require rigorous comparison with established fillers.
Objectives: To assess the non-inferiority and safety of a new cross-linked HA filler, SkinPlus-HYAL Implant Lidocaine (test), versus RESTYLANE Lidocaine (control) for temporary correction of moderate to severe NLFs.
Methods: In this multicenter, randomized, subject- and evaluator-blinded, split-face study, 100 adults with moderate or severe NLFs received the test filler in one NLF and the control in the contralateral NLF. Efficacy was analyzed in the Full Analysis Set (N=93). The primary endpoint was the between-treatment difference in Wrinkle Severity Rating Scale (WSRS) scores at Week 24. Safety was evaluated in the Safety Set (N=100). Group differences were analyzed using a two-sample t-test.
Results: At Week 24, mean WSRS scores were 1.85±0.72 (test) and 1.84±0.68 (control). The mean difference (test - control) was 0.01±0.48, with an upper 97.5% one-sided confidence limit of 0.2136, below the prespecified non-inferiority margin of 0.29. Investigator-rated Global Aesthetic Improvement Scale (GAIS) scores at Week 24 and subject-rated GAIS scores at Week 8 favored the test filler. Local adverse event were more frequent with the test (92.00%) than the control (82.0%), but severe injection-site reactions were uncommon, and no serious adverse events occurred.
Conclusions: SkinPlus-HYAL Implant Lidocaine was non-inferior to RESTYLANE Lidocaine for correction of moderate to severe NLFs and maintained efficacy through 48 weeks. Despite a higher rate of local reactions, its overall safety profile was acceptable, supporting its use as an effective, safe option for facial aesthetic augmentation.
{"title":"Safety and Effectiveness of a Cross-linked Hyaluronic Acid Filler in Korean Subjects for the Correction of Nasolabial Folds: A Randomized, Subject- and Evaluator-blind, Paired Study.","authors":"Si-Hyung Lee, Eunsoo Park, Chong Hyun Won","doi":"10.1093/asj/sjag003","DOIUrl":"https://doi.org/10.1093/asj/sjag003","url":null,"abstract":"<p><strong>Background: </strong>Hyaluronic acid (HA) dermal fillers are widely used as a non-surgical treatment for facial aging, including nasolabial folds (NLFs). As demand for convenient aesthetic procedures increases, new HA products require rigorous comparison with established fillers.</p><p><strong>Objectives: </strong>To assess the non-inferiority and safety of a new cross-linked HA filler, SkinPlus-HYAL Implant Lidocaine (test), versus RESTYLANE Lidocaine (control) for temporary correction of moderate to severe NLFs.</p><p><strong>Methods: </strong>In this multicenter, randomized, subject- and evaluator-blinded, split-face study, 100 adults with moderate or severe NLFs received the test filler in one NLF and the control in the contralateral NLF. Efficacy was analyzed in the Full Analysis Set (N=93). The primary endpoint was the between-treatment difference in Wrinkle Severity Rating Scale (WSRS) scores at Week 24. Safety was evaluated in the Safety Set (N=100). Group differences were analyzed using a two-sample t-test.</p><p><strong>Results: </strong>At Week 24, mean WSRS scores were 1.85±0.72 (test) and 1.84±0.68 (control). The mean difference (test - control) was 0.01±0.48, with an upper 97.5% one-sided confidence limit of 0.2136, below the prespecified non-inferiority margin of 0.29. Investigator-rated Global Aesthetic Improvement Scale (GAIS) scores at Week 24 and subject-rated GAIS scores at Week 8 favored the test filler. Local adverse event were more frequent with the test (92.00%) than the control (82.0%), but severe injection-site reactions were uncommon, and no serious adverse events occurred.</p><p><strong>Conclusions: </strong>SkinPlus-HYAL Implant Lidocaine was non-inferior to RESTYLANE Lidocaine for correction of moderate to severe NLFs and maintained efficacy through 48 weeks. Despite a higher rate of local reactions, its overall safety profile was acceptable, supporting its use as an effective, safe option for facial aesthetic augmentation.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Critical Considerations on the Study of Lunaphil Ultra and Juvéderm Ultra 4 for Nasolabial Folds Treatment.","authors":"Lianchu Li, Jing Zhong, Xiyuan Li","doi":"10.1093/asj/sjag001","DOIUrl":"https://doi.org/10.1093/asj/sjag001","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145909871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Infraorbital hollowing (IOH) is characterized by a sunken appearance of the lower eyelid. The soft-tissue filler VYC-15L has been demonstrated to be effective in correcting IOH in U.S. and European populations.
Objectives: To assess the safety and effectiveness of VYC-15L treatment in Chinese adults with moderate to severe IOH.
Methods: In this randomized, multi-center, 12-month study, the primary endpoint was the proportion of ≥1-grade improvements on the Allergan Infraorbital Hollowing Scale (AIHS) according to the evaluating investigator (EI) at Month 3. Secondary endpoints included EI- and participant-based assessments using the Global Aesthetic Improvement Scale (GAIS) and FACE-Q responses evaluated at Month 3. Safety was monitored throughout.
Results: The primary endpoint was met with a 94.6% AIHS responder rate in the VYC-15L group versus 0.0% in the delayed-treatment control (DTC) group (P < .0001). Significant GAIS improvements in VYC-15L versus DTC participants were seen in EI-assessed (99.1% vs 0.0%) and participant-assessed (95.6% vs 5.7%) responder rates at Month 3 (P < .0001). The mean change in FACE-Q scores was greater in the VYC-15L group compared with the DTC group at Month 3 (P < .0001). Improvements from VYC-15L treatment were seen across all effectiveness measures through Month 12. Mean pain scores were 2.9. Most ISRs were mild and resolved within 14 days. Forty-six participants (28.8%) experienced treatment-emergent AEs (TEAEs), including treatment-related TEAEs (1.7%), which were blepharospasm (0.8%) and injection site bruising (0.8%). No serious TEAEs were reported.
Conclusions: VYC-15L was effective and well tolerated for IOH correction in Chinese adults up to 1 year.
背景:眶下空心症(IOH)以下眼睑凹陷为特征。软组织填充物VYC-15L已被证明在美国和欧洲人群中矫正IOH是有效的。目的:评价VYC-15L治疗中国成人中重度IOH的安全性和有效性。方法:在这项随机、多中心、为期12个月的研究中,主要终点是根据评估研究者(EI)在第3个月时对Allergan眶下空心化量表(AIHS)≥1级改善的比例。次要终点包括基于EI和参与者的评估,使用全球审美改善量表(GAIS)和在第3个月评估的FACE-Q反应。安全受到全程监控。结果:VYC-15L组达到了主要终点,AIHS应答率为94.6%,延迟治疗对照组(DTC)为0.0% (P < 0.0001)。与DTC参与者相比,VYC-15L参与者在第3个月的ei评估(99.1% vs 0.0%)和参与者评估(95.6% vs 5.7%)应答率上的GAIS显著改善(P < 0.0001)。第3个月,VYC-15L组FACE-Q评分的平均变化大于DTC组(P < 0.0001)。在第12个月的所有有效性测量中,VYC-15L治疗均有改善。平均疼痛评分为2.9分。大多数isr是轻微的,在14天内消退。46名参与者(28.8%)经历了治疗突发事件(teae),包括治疗相关的teae(1.7%),即眼睑痉挛(0.8%)和注射部位瘀伤(0.8%)。没有严重的tees报告。结论:VYC-15L对中国成人IOH矫正1年有效且耐受性良好。
{"title":"Improved Infraorbital Hollowing in Chinese Adults Following Hyaluronic Acid-Based Filler With Lidocaine (VYC-15L) Treatment.","authors":"Nanze Yu, Xiaojun Wang, Wenyu Wu, Hongyi Zhao, Zhenyu Chen, Yan Wu, Qian Tan, Ziyang Liu, Smita Chawla","doi":"10.1093/asj/sjaf267","DOIUrl":"https://doi.org/10.1093/asj/sjaf267","url":null,"abstract":"<p><strong>Background: </strong>Infraorbital hollowing (IOH) is characterized by a sunken appearance of the lower eyelid. The soft-tissue filler VYC-15L has been demonstrated to be effective in correcting IOH in U.S. and European populations.</p><p><strong>Objectives: </strong>To assess the safety and effectiveness of VYC-15L treatment in Chinese adults with moderate to severe IOH.</p><p><strong>Methods: </strong>In this randomized, multi-center, 12-month study, the primary endpoint was the proportion of ≥1-grade improvements on the Allergan Infraorbital Hollowing Scale (AIHS) according to the evaluating investigator (EI) at Month 3. Secondary endpoints included EI- and participant-based assessments using the Global Aesthetic Improvement Scale (GAIS) and FACE-Q responses evaluated at Month 3. Safety was monitored throughout.</p><p><strong>Results: </strong>The primary endpoint was met with a 94.6% AIHS responder rate in the VYC-15L group versus 0.0% in the delayed-treatment control (DTC) group (P < .0001). Significant GAIS improvements in VYC-15L versus DTC participants were seen in EI-assessed (99.1% vs 0.0%) and participant-assessed (95.6% vs 5.7%) responder rates at Month 3 (P < .0001). The mean change in FACE-Q scores was greater in the VYC-15L group compared with the DTC group at Month 3 (P < .0001). Improvements from VYC-15L treatment were seen across all effectiveness measures through Month 12. Mean pain scores were 2.9. Most ISRs were mild and resolved within 14 days. Forty-six participants (28.8%) experienced treatment-emergent AEs (TEAEs), including treatment-related TEAEs (1.7%), which were blepharospasm (0.8%) and injection site bruising (0.8%). No serious TEAEs were reported.</p><p><strong>Conclusions: </strong>VYC-15L was effective and well tolerated for IOH correction in Chinese adults up to 1 year.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145909832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}