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Sterile gowns for spinal anaesthesia – environmental cost without clinical gain? 用于脊髓麻醉的无菌袍--环境成本高昂却无临床收益?
IF 7.5 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-09-03 DOI: 10.1111/anae.16423
Stephen Waite, Charlotte Collison, Ronan Mukherjee
<p>We read with interest the article by Ledda et al. [<span>1</span>], which highlights a drive to change from single-use to reusable gowns to be more environmentally sustainable. While laudable, we feel that it does not consider wider changes to our practice which could have an impact of greater magnitude.</p><p>Standard practice in many UK centres is to wear a sterile gown for spinal anaesthesia to reduce the incidence of infective complications. This practice is mandated in the 2014 Association of Anaesthetists guidance [<span>2</span>]. However, this practice is not standard globally. In the UK, practice varies for other neuraxial procedures, e.g. many doctors from medical specialities do not wear a sterile gown for lumbar punctures.</p><p>Most anaesthetists are cognisant of the risk of infective complications. However, the incidence of infection following single-shot spinal anaesthesia is very low. The 3rd UK National Audit Project (NAP3) reported only two cases of vertebral canal abscess and one of infective meningitis associated with approximately 325,000 spinal anaesthetics [<span>3</span>]. It noted failings of asepsis and specifically referenced the importance of sterile drapes and use of facemasks, but did not specifically mention sterile gowns. Beyond NAP3 there is very little evidence for the use of sterile gowns. Only a single randomised controlled trial has been identified [<span>4</span>], which investigated gowning on the incidence of catheter tip colonisation in lumbar epidural for labour analgesia. Siddiqui et al. concluded that the use of gowns did not affect catheter colonisation.</p><p>The volume of waste generated using sterile gowns for spinal anaesthesia is significant. In NHS Tayside, a health board with a patient population of 416,090 (2017 Census), we undertook 2877 spinal anaesthetics in 2022. Gowns generated nearly half a metric tonne of carbon dioxide equivalent (CO<sub>2</sub>e) from disposal in clinical waste. These gowns are manufactured in China, and it is challenging to estimate the (likely extensive) additional environmental cost of production and shipping to the UK. As stated, NAP3 estimated that there were approximately 325,000 spinal anaesthetics undertaken in the UK in 2009 [<span>3</span>]. Using a sterile gown for every spinal anaesthetic generates vast amounts of CO<sub>2</sub>e.</p><p>Many anaesthetists seem to be receptive to a change of practice in this area. Tuohey et al. raised similar concerns in 2023 and called for a change in practice in the UK and Australasia [<span>5</span>]. When we surveyed 51 anaesthetists in NHS Tayside, 89.9% of respondents were receptive to changing their practice if supported by a change in guidance. While changing to reusable alternatives may help environmentally and financially, it seems that high quality asepsis for single-shot spinal anaesthesia can still be achieved without the use of a sterile gown, and that individual clinicians should be encouraged to choose wha
我们饶有兴趣地阅读了 Ledda 等人的文章[1],其中强调了将一次性手术衣改为可重复使用手术衣以实现环境可持续发展的动力。英国许多中心的标准做法是穿无菌手术衣进行脊髓麻醉,以降低感染性并发症的发生率。2014 年麻醉师协会指南规定了这一做法[2]。然而,这一做法并非全球标准。在英国,其他神经轴手术的做法也不尽相同,例如,许多医学专业的医生在腰椎穿刺时并不穿无菌袍。然而,单次脊髓穿刺麻醉后的感染发生率非常低。第三届英国国家审计项目(NAP3)仅报告了两例椎管脓肿和一例感染性脑膜炎,与大约 325,000 例脊髓麻醉相关[3]。该项目指出了无菌操作的失误,并特别提到了无菌帘布和使用面罩的重要性,但并未特别提及无菌袍。除 NAP3 外,使用无菌袍的证据很少。仅有一项随机对照试验[4]调查了腰硬膜外分娩镇痛时穿无菌衣对导管尖端定植发生率的影响。Siddiqui 等人得出结论,使用手术衣不会影响导管的定植。英国国家医疗服务系统泰赛德卫生委员会的患者人数为 416,090 人(2017 年人口普查),2022 年我们进行了 2877 例脊柱麻醉。手术衣在临床废物中的处置产生了近半公吨二氧化碳当量(CO2e)。这些手术衣是在中国生产的,因此很难估算生产和运往英国的额外环境成本(可能很高)。如前所述,据 NAP3 估计,2009 年英国约有 325,000 例脊柱麻醉[3]。每次脊柱麻醉时使用无菌袍都会产生大量的 CO2e。Tuohey 等人在 2023 年提出了类似的担忧,并呼吁英国和澳大拉西亚改变做法[5]。我们对 NHS 泰赛德地区的 51 名麻醉师进行了调查,89.9% 的受访者表示,如果有指南的支持,他们愿意改变自己的做法。虽然改用可重复使用的替代品可能会对环境和经济有所帮助,但似乎在不使用无菌袍的情况下仍可实现单次脊髓麻醉的高质量无菌操作,因此应鼓励临床医师选择最适合自己的操作方式。包括麻醉师协会在内的国家指南强制规定了这种做法,这阻碍了变革,也阻碍了今后在这一领域的任何研究。
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引用次数: 0
Comparison between adjusted Montreal Cognitive Assessment and neuropsychological assessment for diagnosing postoperative neurocognitive disorders 调整后的蒙特利尔认知评估与神经心理学评估在诊断术后神经认知障碍方面的比较。
IF 7.5 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-09-03 DOI: 10.1111/anae.16424
Annerixt Gribnau, Gert J. Geurtsen, Hanna C. Willems, Jeroen Hermanides, Mark L. van Zuylen
<p>The current gold standard neuropsychological assessment for detecting postoperative neurocognitive disorders is too time-consuming, costly and burdensome to use in clinical practice. Brief screening instruments, such as the Montreal Cognitive Assessment (MoCA), are used frequently instead. However, previous research by our team suggested that the original MoCA is not suitable to detect postoperative neurocognitive disorders in older adult surgical patients [<span>1</span>]. To improve the accuracy of the MoCA, Kessels et al. presented norms controlling for age, sex and educational level [<span>2</span>]. Accordingly, our study aimed to compare the performance of the adjusted MoCA score in diagnosing postoperative neurocognitive disorder.</p><p>We prospectively enrolled patients aged ≥ 65 y scheduled for elective surgery, involving any type of anaesthesia or surgical procedure, from September 2019 to January 2021, after approval by our local research ethics committee. Patients who were not fluent in Dutch, had pre-operative cognitive impairment, severe hearing impairment or needed several procedures under anaesthesia were not studied. The original study is described in full elsewhere [<span>1</span>]. Simultaneous administration of neuropsychological assessment and MoCA occurred pre-operatively and 30–60 days postoperatively, using alternate versions to minimise practice effect. Performance on neuropsychological assessment was reported as T-scores after comparison to a Dutch norm group (https://andi.nl). For neuropsychological assessment, a decline of 1–2 SD on ≥ 1 cognitive domain score indicated mild postoperative cognitive disorder, and ≥ 2 SD decline indicated major postoperative neurocognitive disorder [<span>3</span>]. In the post hoc analysis, we transformed the original, education-uncorrected, MoCA scores to percentiles according to Kessels et al. [<span>2</span>]. Mild postoperative neurocognitive disorder was defined as a reliable change index decrease of 1–2 SD [<span>4</span>] and ≥ 2 SD decline indicated major postoperative neurocognitive disorder. Test–retest reliability was measured by intraclass correlation coefficient. Data were missing completely at random and were imputed.</p><p>Sensitivity, specificity and area under the receiver operating characteristic curve of the adjusted MoCA were calculated. We examined pre-operative, postoperative and pre- to postoperative correlations of MoCA and total neuropsychological assessment and domain scores. We transformed the outcome to z-scores to assess agreement between MoCA and neuropsychological assessment by Bland–Altman plots. Ordinary or regression limits of agreement were chosen based on the presence or absence of proportional bias [<span>5</span>].</p><p>A total of 73 patients completed neuropsychological assessment and MoCA. Baseline characteristics are detailed in online Supporting Information Appendix S1. Neuropsychological assessment identified 14 (19%) cases of postoperative
目前用于检测术后神经认知障碍的金标准神经心理学评估耗时过长、成本过高且负担过重,无法在临床实践中使用。蒙特利尔认知评估(MoCA)等简易筛查工具被频繁使用。然而,我们团队之前的研究表明,原始的 MoCA 并不适合检测老年手术患者的术后神经认知障碍[1]。为了提高 MoCA 的准确性,Kessels 等人提出了控制年龄、性别和教育程度的标准[2]。因此,我们的研究旨在比较调整后的MoCA评分在诊断术后神经认知障碍方面的表现。经当地研究伦理委员会批准后,我们在2019年9月至2021年1月期间前瞻性地招募了年龄≥65岁的择期手术患者,涉及任何类型的麻醉或外科手术。荷兰语不流利、术前有认知障碍、严重听力障碍或需要多次麻醉的患者不在研究范围内。原始研究的全部内容见其他文献[1]。术前和术后30-60天同时进行神经心理评估和MoCA,使用不同的版本以尽量减少实践影响。神经心理评估的成绩在与荷兰常模组(https://andi.nl)比较后以 T 分数的形式报告。在神经心理学评估中,认知领域得分≥1 分下降 1-2 SD 表示轻度术后认知障碍,下降≥2 SD 表示重度术后神经认知障碍[3]。在事后分析中,我们根据 Kessels 等人[2]的方法将未经教育校正的原始 MoCA 分数转换为百分位数。轻度术后神经认知障碍的定义是可靠变化指数下降 1-2 SD [4],下降≥ 2 SD 表示重度术后神经认知障碍。通过类内相关系数测量重测可靠性。计算了调整后 MoCA 的灵敏度、特异性和接收者操作特征曲线下面积。我们研究了术前、术后以及术前到术后MoCA与神经心理评估总分和领域得分的相关性。我们将结果转换为z-分数,通过布兰德-阿尔特曼图评估MoCA和神经心理学评估之间的一致性。根据是否存在比例偏差[5],我们选择了普通或回归的一致性限值。共有 73 名患者完成了神经心理评估和 MoCA。基线特征详见在线辅助信息附录 S1。神经心理学评估确定了 14 例(19%)术后神经认知障碍患者,MoCA 诊断了 15 例(21%)认知障碍患者。只有两个病例同时被两种工具确诊(表 1)。神经心理学评估将所有患者归类为轻度术后神经认知障碍,MoCA 诊断出 3 例重度认知障碍患者;然而,其中只有 1 例同时被神经心理学评估诊断为术后神经认知障碍。调整后的MoCA的重测可靠性为中等(在线证明资料附录S2)。接收者操作特征曲线下面积为 0.54(95%CI 0.38-0.70)。术前调整后的MoCA和神经心理评估领域得分之间的相关性为弱至中等(r = 0.12-0.48)。术后相关性很弱到很弱(r = -0.03-0.28),术前与术后MoCA相关性很弱(r = -0.10-0.09)(在线证明资料附录S3)。我们的研究结果表明,尽管对年龄、性别和教育程度进行了调整,但MoCA仍不足以诊断老年择期手术患者术后的神经认知障碍。它不应被用于术后神经认知障碍的临床或研究目的,这与我们之前的研究结果一致[1]。调整后的 MoCA(0.14-0.78)和原始 MoCA(0.21-0.84)的灵敏度和特异性相当。MoCA的不足之处可能是由于术后神经认知障碍患者认知变化的微妙性,因为MoCA仅适用于监测痴呆症患者认知的巨大变化[6]。
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引用次数: 0
Breathing system terminology 呼吸系统术语
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/j.1365-2044.1997.tb00104.x
D. M. Lowe, S. W. M. Feaver
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引用次数: 0
My anaesthetic machine's on fire 我的麻醉机着火了
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/j.1365-2044.1997.tb00099.x
S. Rogers, M. W Davies
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引用次数: 0
Mortality predicted by APACHE II. The effect of changes in physiological values on predicted hospital mortality APACHE II 预测的死亡率。生理值变化对预测住院死亡率的影响
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/j.1365-2044.1997.tb00097.x
R. D. Tunnell, A. W. Miller, G. B. Smith
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引用次数: 0
NAP7 – what's the point? NAP7 - 有什么意义?
IF 7.5 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/anae.16422
Jasmeet Soar, Tim M. Cook, Richard A. Armstrong, Emira Kursumovic, Fiona C. Oglesby, Andrew D. Kane
<p>Ward and Illif ask whether there have been too many papers on the 7th UK National Audit Project (NAP7) and whether the “<i>primary purpose</i>” of the project has been lost [<span>1</span>]. NAP7 was a massive project during a pandemic. It is unsurprising that peri-operative cardiac arrest and its contributing factors have generated a large amount of information given this is the final common pathway for serious complications of anaesthesia and surgery [<span>2</span>]. These include those studied in previous NAPs (e.g. airway complications, anaphylaxis) [<span>2</span>]. Of note, NAP7 reported on more cases than NAPs 3–6 combined [<span>3</span>].</p><p>We have a duty to share our findings as widely as possible; for our patients, their families, our stakeholders and the thousands of anaesthetists in the UK and Ireland who contributed data to NAP7. In addition to providing new information about complications and for different patients or subspecialties (e.g. children [<span>4</span>], obstetrics [<span>5</span>]), secondary outputs have been driven by our stakeholders. NAP7 has provided novel and up-to-date information in several areas that are important or contentious for anaesthetists and our patients (e.g. impact of COVID-19 [<span>6</span>], use of monitoring [<span>7</span>], the independent sector [<span>8</span>], anaesthesia associates [<span>9</span>] and wellbeing [<span>3</span>]).</p><p>At all stages, we made efforts to minimise the number of chapters and the length of these to improve accessibility. An illustration of this is the NAP7 ‘airway and breathing’ chapter and paper [<span>10</span>] that reports on 113 cases and runs to 12 pages compared with NAP4 which included 133 anaesthesia airway cases and runs to 216 pages. The division of the report into discrete short chapters specifically enables and encourages readers to focus on areas most relevant to their areas of practice.</p><p>Many of the report chapters have been subsequently published as papers in <i>Anaesthesia</i>, often with additional data and discussion. No project is complete until it is disseminated, and it was, therefore, an intentional strategy to improve visibility of the project by publishing key topic chapters as papers, after full peer review. This further enabled dissemination through podcasts and social media. We judge this a success and thank <i>Anaesthesia</i> and its editors.</p><p>The prime purpose of the NAPs is “<i>through national effort to provide detailed numerical and case</i>-<i>based analysis of risk and complications of anaesthesia and surgery, to make these data available to patients and clinicians and in so doing so facilitate better communication and decision making and drive changes that improve safety</i>”. We believe all the findings and recommendations of NAP7 will help make anaesthesia safer and are important for anaesthetists and their patients – we have no regrets about sharing them as widely as possible.</p><p>Finally, we thank War
Ward 和 Illif 提出了一个问题:关于第七次英国国家审计项目(NAP7)的论文是否太多,项目的 "主要目的 "是否已经丢失[1]。NAP7 是大流行期间的一个大型项目。鉴于围手术期心脏骤停是麻醉和手术严重并发症的最后常见途径,因此围手术期心脏骤停及其诱因产生了大量信息也就不足为奇了[2]。这些并发症包括之前的 NAPs 所研究的并发症(如气道并发症、过敏性休克)[2]。值得注意的是,NAP7 报告的病例数超过了 NAP3-6 的总和[3]。我们有责任尽可能广泛地分享我们的研究结果;为了我们的患者、他们的家属、我们的利益相关者以及为 NAP7 提供数据的英国和爱尔兰成千上万的麻醉医师。除了为不同患者或亚专科(如儿童[4]、产科[5])提供有关并发症的新信息外,我们的利益相关者还推动了二次产出。NAP7 在一些对麻醉医师和患者重要或有争议的领域(如 COVID-19 的影响[6]、监测的使用[7]、独立部门[8]、麻醉相关人员[9]和福利[3])提供了新颖的最新信息。例如,NAP7 "气道和呼吸 "章节和论文[10]报告了 113 个病例,长达 12 页,而 NAP4 包括 133 个麻醉气道病例,长达 216 页。将报告划分为独立的短章节,特别有助于并鼓励读者将注意力集中在与其实践领域最相关的方面。任何项目在传播之前都是不完整的,因此,在经过全面的同行评审后,将关键主题章节作为论文发表,是提高项目知名度的有意策略。这进一步促进了通过播客和社交媒体的传播。我们认为这是一次成功,并对《麻醉学》及其编辑表示感谢。"国家行动计划 "的主要目的是 "通过全国性的努力,提供有关麻醉和手术风险及并发症的详细数字和基于病例的分析,向患者和临床医生提供这些数据,从而促进更好的沟通和决策,推动提高安全性的变革"。我们相信,NAP7 的所有研究结果和建议都将有助于提高麻醉的安全性,对麻醉师及其患者都非常重要--我们无怨无悔地尽可能广泛地分享这些结果和建议。最后,我们感谢 Ward 和 Illif 对 NAP7 项目和信息图表[1]的全面性和传播性的赞扬。在回答他们和同事应该阅读哪些大量成果时,我们鼓励每位麻醉师阅读 2023 年 11 月发表在《麻醉学》上的主要论文。我们还建议阅读报告中的摘要章节[3],其中包括旨在使麻醉护理更安全的主要发现和 20 项主要建议。虽然很少有人会阅读整份报告,但我们鼓励麻醉医师阅读他们感兴趣的论文和章节。我们希望这能激发大家更深入地阅读该报告,其中包括关于风险、低风险患者心脏骤停、良好实践等其他重要章节。
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引用次数: 0
Uptake of desflurane: A reply 地氟醚的吸收:答复
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/j.1365-2044.1997.tb00095.x
T. J. Walker, G. C. Lockwood
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引用次数: 0
Academic anaesthetists 学术麻醉师
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/j.1365-2044.1997.tb00092.x
S. L. Snowdon
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引用次数: 0
A persistent problem with glass ampoules 玻璃安瓿瓶的一个老大难问题
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/j.1365-2044.1997.tb00111.x
P. C. Stewart
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引用次数: 0
A persistent problem with glass ampoules: A reply 玻璃安瓿瓶的一个老大难问题:答复
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2024-08-27 DOI: 10.1111/j.1365-2044.1997.tb00112.x
R. Albanese
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引用次数: 0
期刊
Anaesthesia
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