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Mandatory training for rare anaesthetic events – a philosophical view 罕见麻醉事件的强制训练——哲学观点
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-23 DOI: 10.1111/anae.16552
Christopher Frerk, Genevieve Evans
<p>Murphy's letter opposing the call for mandatory training for rare anaesthetic events [<span>1</span>] challenges issues inferred, but not contained, in the editorial by Nathanson et al. [<span>2</span>]. For example, Nathanson et al. did not suggest that training would make individual humans less error prone. They proposed that we should be training staff to work in multidisciplinary teams, as teamwork can help us identify and correct the inevitable errors of our colleagues and can help them identify and correct ours. While the concepts of teamwork can, and should, be learned through lectures and reading existing literature, developing and refining the non-technical skills required for good teamwork requires training and deliberate practice, with targeted positive feedback. Simulation is the ideal learning environment for this, allowing non-technical skills to be observed, practised and improved. Murphy also seemed particularly concerned about the possibility of sanctions for failing to meet standards, but sanctions do not have a role in simulation training, and they were not mentioned by Nathanson et al.</p><p>In response to Murphy's philosophical position that we should view this issue through a utilitarian lens, we believe that a Kantian perspective would be much more appropriate. Utilitarianism can be summarised as the greatest good for the greatest number of people; it is important to recognise that this is based on consequentialism, meaning that, when we act, we are trying to predict how much good the act will produce, as opposed to whether the act is good [<span>3</span>]. The Kantian approach is deontological in nature. This means our actions are judged as objectively good or bad based on ethical values and principles, rather than predicted consequences [<span>4</span>]. According to Kant, what matters is the ethical or moral value of an action. While outcomes are important, it is vital to recognise that, instead of trying to anticipate the optimal outcomes for all parties involved, we have a duty to act in the most ethically correct way for our patients. This includes supporting all measures to ensure that we, as doctors, are appropriately trained to deal with serious rare events that we know cause death and disability. This, therefore, includes supporting the call by Nathanson et al. for mandatory training [<span>2</span>].</p><p>The second relevant element of Kantian ethics is found within his categorical imperative, which boils down to the principle of universalisation [<span>5</span>]: “<i>if I act in a certain way, I should be content with everyone else also acting in this way</i>”. This mirrors the question posed by Nathanson et al.: “<i>would we be happy if a member of our family were under the care of an anaesthetist who was unable to demonstrate they could safely manage inadvertent oesophageal intubation or acute anaphylaxis to a neuromuscular blocking drug?</i>” [<span>2</span>]. We believe anaesthetists would answer this
Murphy反对对罕见麻醉事件进行强制训练的呼吁,这封信挑战了Nathanson等人在社论中推断出的问题,但没有包含在内。例如,Nathanson等人并没有提出训练可以减少个人犯错的可能性。他们建议我们应该培训员工在多学科团队中工作,因为团队合作可以帮助我们识别和纠正同事不可避免的错误,也可以帮助他们识别和纠正我们的错误。虽然团队合作的概念可以而且应该通过讲座和阅读现有文献来学习,但培养和完善良好团队合作所需的非技术技能需要训练和刻意练习,并有针对性的积极反馈。模拟是理想的学习环境,可以观察、练习和提高非技术技能。墨菲似乎也特别关注未能达到标准的制裁的可能性,但制裁在模拟训练中没有作用,Nathanson等人也没有提到制裁。对于墨菲的哲学立场,我们应该通过功利主义的视角来看待这个问题,我们认为康德的观点会更合适。功利主义可以概括为最大数量的人的最大利益;重要的是要认识到这是基于结果主义的,也就是说,当我们采取行动时,我们试图预测该行为会产生多少好处,而不是该行为是否为好。康德的方法本质上是义务论的。这意味着我们的行为是根据道德价值观和原则客观判断的好或坏,而不是预测的后果。康德认为,重要的是行为的伦理或道德价值。虽然结果很重要,但认识到这一点至关重要,而不是试图预测所有相关方的最佳结果,我们有责任以最合乎道德的方式为患者行事。这包括支持所有措施,以确保我们作为医生得到适当的培训,以处理我们知道会导致死亡和残疾的严重罕见事件。因此,这包括支持Nathanson等人对强制性培训[2]的呼吁。康德伦理学的第二个相关元素可以在他的绝对命令中找到,它可以归结为普遍性原则:“如果我以某种方式行事,我应该满足于其他人也以这种方式行事”。这反映了Nathanson等人提出的问题:“如果我们的家庭成员在麻醉师的护理下,而麻醉师无法证明他们可以安全地处理无意的食管插管或神经肌肉阻断药物的急性过敏反应,我们会高兴吗?””[2]。我们相信麻醉师会用一个响亮的“不”来回答这个问题,支持强制性培训是必要的这一论点。最后,尽管我们同意墨菲的观点,即从成功中学习是有价值的,但我们需要认识到,成功很少来自卓越的个人表现,而是来自良好的团队合作,而当罕见的严重并发症发生时,这同样会有所帮助。从道德、伦理、科学和哲学的角度来看,显然是时候对罕见的麻醉事件实施强制性的终身培训了。该培训应强调多学科危机管理和人为因素,以提高患者安全。
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引用次数: 0
Similarities and differences between maternal and major traumatic haemorrhage – what can we learn? 产妇出血与严重外伤性出血的异同——我们能从中学到什么?
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-23 DOI: 10.1111/anae.16544
Benjamin Stretch, Paola Eiben, James O'Carroll
<p>We read the correspondence from Margiotta and Plaat with interest [<span>1</span>]. There could be much gained by comparing major obstetric and traumatic haemorrhage. Three areas that we believe are particularly relevant are identification of hypovolaemia and coagulopathy, and the impact of human factors.</p><p>The 7th National Audit Project (NAP7) authors identified that hypovolaemia was under-recognised and inadequately treated in obstetric patients who had a cardiac arrest [<span>2</span>]. Trauma research suggests multimodal assessments of volume status are important, as individual parameters and scoring systems lack sensitivity and specificity. In addition to heart rate and blood pressure, capillary refill, pulse pressure, base deficit and lactate, coagulopathy and estimated blood loss may be most useful and should be used in combination. Shock index can be a predictor of the severity of shock in trauma, but not in the obstetric population.</p><p>The NAP7 authors recommended the use of fluid resuscitation and vasopressor use in obstetric haemorrhage [<span>2</span>]. In the major trauma setting, acidaemia, hypothermia, hyperkalaemia, hypocalcaemia and coagulopathy are associated with worse outcomes. Consequently, early transfusion of blood products and management of metabolic disturbance are of the upmost importance. Viscoelastic haemostatic assay-driven therapy represents the ‘gold standard’ in trauma care and is recommended by international guidelines [<span>3</span>]. The importance of targeted therapy was emphasised by CRYOSTAT-2, showing no advantage to empirical cryoprecipitate use in major trauma and worse outcomes if given before depletion of fibrinogen [<span>4</span>]. Pregnancy is accompanied by significant changes in the coagulation and fibrinolytic systems including increased fibrinogen concentrations (3.5–6.5 g.l<sup>-1</sup>) [<span>5</span>]. Hypofibrinogenaemia is associated with poor outcomes and, as a result, a higher fibrinogen target of 2 g.l<sup>-1</sup> is recommended.</p><p>We must also consider fetal wellbeing. To preserve uterine blood flow, maternal systemic blood pressure should be maintained near normal before delivery. As such, hypotensive resuscitation, which can be an advantageous approach in damage control resuscitation in trauma [<span>3</span>], is not the mainstay in obstetrics.</p><p>Multidisciplinary teamwork, effective communication and human factors are key in managing both obstetric and traumatic major haemorrhage, with failure of these recognised as a contributor to maternal morbidity and mortality by MBRRACE-UK [<span>6</span>]. Non-technical skills including situational awareness, appropriate role allocation and performance under pressure in stressful situations are important.</p><p>Comparing obstetric and traumatic haemorrhage highlights that not all bleeding is the same, as they differ significantly in physiological response and risk of coagulopathy. These differences are influenced by a
我们饶有兴趣地读了马焦塔和普拉特的来信。通过比较产科大出血和外伤性出血,可以获得很多信息。我们认为特别相关的三个领域是低血容量和凝血功能障碍的识别,以及人为因素的影响。第七次国家审计项目(NAP7)的作者发现,在患有心脏骤停的产科患者中,低血容量未得到充分认识和治疗。创伤研究表明,由于单个参数和评分系统缺乏敏感性和特异性,多模式容量状态评估很重要。除了心率和血压外,毛细血管充盈、脉压、基础缺陷和乳酸、凝血功能障碍和估计失血量可能是最有用的,应该联合使用。休克指数可以预测创伤休克的严重程度,但不是在产科人群。NAP7的作者建议在产科出血中使用液体复苏和血管加压剂。在重大创伤情况下,酸血症、低体温、高钾血症、低钙血症和凝血功能障碍与较差的预后相关。因此,早期输血和代谢紊乱的管理是最重要的。粘弹性止血试验驱动的治疗代表了创伤治疗的“金标准”,并被国际指南[3]推荐。CRYOSTAT-2强调了靶向治疗的重要性,表明在重大创伤中使用低温沉淀没有优势,如果在纤维蛋白原[4]耗尽之前给予,结果会更差。妊娠伴随着凝血和纤溶系统的显著变化,包括纤维蛋白原浓度升高(3.5-6.5 g.l-1)。低纤维蛋白原血症与不良预后相关,因此,纤维蛋白原目标较高,为2 g。推荐使用L-1。我们还必须考虑胎儿的健康。为保持子宫血流量,分娩前应保持母体体表血压接近正常。因此,低血压复苏在创伤bbb的损害控制复苏中可能是一种有利的方法,但在产科却不是主要的方法。多学科的团队合作,有效的沟通和人为因素是管理产科和创伤性大出血的关键,MBRRACE-UK[6]认为这些失败是孕产妇发病率和死亡率的一个因素。非技术技能,包括情景意识、适当的角色分配和在压力下的表现都很重要。比较产科出血和外伤性出血突出表明,并非所有出血都是相同的,因为它们在生理反应和凝血功能障碍的风险方面存在显着差异。这些差异受患者潜在的生理状态和出血的具体原因的影响。通过了解两种类型出血之间的这些相似之处和区别,我们可以潜在地提高患者的预后。
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引用次数: 0
Pre-operative subjective functional capacity and postoperative outcomes in adult non-cardiac surgery: a systematic review and meta-analysis
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-23 DOI: 10.1111/anae.16543
Kyosuke Takahashi, Kyoko Chiba, Ayano Honda, Yusuke Iizuka, Koichi Yoshinaga, Alka Sachin Deo, Tokujiro Uchida
Assessment of functional capacity is an essential part of peri-operative risk stratification. Subjective functional capacity is easier to examine than objective tests of patient fitness. However, the association between subjective functional capacity and postoperative outcomes has not been established.
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引用次数: 0
Incidence of 12-month postoperative cognitive decline following regional vs. general anaesthesia in older patients undergoing hip fracture surgery: follow-up of the RAGA trial
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-23 DOI: 10.1111/anae.16545
Ting Li, Jun Li, Chenchen Jiang, Liyong Yuan, Jinze Wu, Ali Mazaheri, Mingcang Wang, Shengwei Jin, Paul S. Myles, Yinguang Yao, Jimin Wu, Junping Chen, Fang G. Smith
Data regarding the incidence of 12-month postoperative cognitive decline following regional or general anaesthesia in older patients undergoing hip fracture surgery remain observational. Compared with general anaesthesia, we hypothesised that regional anaesthesia would decrease the incidence of 12-month postoperative cognitive decline.
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引用次数: 0
Instrumental variable analyses – an alternative to regression? 工具变量分析-回归的替代方案?
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-17 DOI: 10.1111/anae.16549
Siu‐Wai Choi
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点击文章标题阅读更多内容。
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引用次数: 0
Gastric point-of-care ultrasound in the GLP-1 receptor agonist era: clinical impact and competency GLP-1受体激动剂时代的胃点护理超声:临床影响和能力
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-15 DOI: 10.1111/anae.16548
Dáire N. Kelly, Sai Pentyala, Stephen C. Haskins
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引用次数: 0
Association of ventilation volumes, pressures and rates with the mechanical power of ventilation in patients without acute respiratory distress syndrome: exploring the impact of rate reduction 无急性呼吸窘迫综合征患者通气气量、压力和通气率与通气机械功率的关系:探讨通气率降低的影响
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-13 DOI: 10.1111/anae.16537
Laura A. Buiteman-Kruizinga, David M. P. van Meenen, Ary Serpa Neto, Guido Mazzinari, Lieuwe D. J. Bos, Pim L. J. van der Heiden, Frederique Paulus, Marcus J. Schultz, , ,
High mechanical power is associated with mortality in patients who are critically ill and require invasive ventilation. It remains uncertain which components of mechanical power – volume, pressure or rate – increase mechanical power the most.
高机械功率与需要有创通气的危重病人的死亡率相关。机械动力的哪个组成部分——体积、压力或速率——最大程度地增加了机械动力,这仍不确定。
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引用次数: 0
Issue Information – Editorial Board 发行信息-编辑委员会
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-13 DOI: 10.1111/anae.16330
Click on the article title to read more.
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引用次数: 0
Elective peri‐operative management of adults taking glucagon‐like peptide‐1 receptor agonists, glucose‐dependent insulinotropic peptide agonists and sodium‐glucose cotransporter‐2 inhibitors: a multidisciplinary consensus statement 选择性服用胰高血糖素样肽- 1受体激动剂、葡萄糖依赖性胰岛素肽激动剂和钠-葡萄糖共转运蛋白- 2抑制剂的成人围手术期管理:多学科共识声明
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-09 DOI: 10.1111/anae.16541
Kariem El‐Boghdadly, Jugdeep Dhesi, Philippa Fabb, Nicholas Levy, Dileep N. Lobo, Andrew McKechnie, Omar Mustafa, Philip Newland‐Jones, Anil Patel, Dimitri J. Pournaras, Ken Clare, Ketan Dhatariya
SummaryIntroductionGlucagon‐like peptide‐1 receptor agonists, dual glucose‐dependent insulinotropic peptide receptor agonists and sodium‐glucose cotransporter‐2 inhibitors are used increasingly in patients receiving peri‐operative care. These drugs may be associated with risks of peri‐operative pulmonary aspiration or euglycaemic ketoacidosis. We produced a consensus statement for the peri‐operative management of adults taking these drugs.MethodsThis multidisciplinary consensus statement included surgeons, anaesthetists, physicians, pharmacists and people with lived experience relevant to these guidelines. Following the directed literature review, a three‐round modified Delphi process was conducted to generate and ratify recommendations.ResultsPatients taking glucagon‐like peptide‐1 receptor agonists and dual glucose‐dependent insulinotropic peptide receptor agonists should: continue these drugs before surgery; have full risk assessment and stratification; and receive peri‐operative techniques that may mitigate risk of pulmonary aspiration before, during and after sedation or general anaesthesia. Patients taking sodium‐glucose cotransporter‐2 inhibitors should omit them the day before and the day of a procedure. All patients should have risks and mitigation strategies discussed with a shared decision‐making approach.DiscussionUntil more evidence becomes available, this pragmatic, multidisciplinary consensus statement aims to support shared decision‐making and improve safety for patients taking glucagon‐like peptide‐1 receptor agonists, dual glucose‐dependent insulinotropic peptide receptor agonists and sodium‐glucose cotransporter‐2 inhibitors during the peri‐operative period.
胰高血糖素样肽- 1受体激动剂、双糖依赖性胰岛素-肽受体激动剂和钠-葡萄糖共转运蛋白- 2抑制剂越来越多地用于接受围手术期护理的患者。这些药物可能与围术期肺误吸或血糖酮症酸中毒的风险相关。我们为服用这些药物的成人的围手术期管理提出了共识声明。方法这份多学科共识声明包括外科医生、麻醉师、内科医生、药剂师和有相关生活经验的人。在直接文献回顾之后,进行了三轮修改的德尔菲过程,以产生和批准建议。结果服用胰高血糖素样肽- 1受体激动剂和双糖依赖性胰岛素肽受体激动剂的患者应:术前继续使用这些药物;有充分的风险评估和分层;并接受围手术期技术,以降低镇静或全身麻醉前、中和后肺误吸的风险。服用钠-葡萄糖共转运蛋白- 2抑制剂的患者应在手术前一天和手术当天停用。所有患者都应该以共同的决策方式讨论风险和缓解策略。讨论:在获得更多证据之前,这一务实的多学科共识声明旨在支持共同决策,并提高围手术期服用胰高血糖素样肽- 1受体激动剂、双葡萄糖依赖性胰岛素肽受体激动剂和钠-葡萄糖共转运蛋白- 2抑制剂的患者的安全性。
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引用次数: 0
Peri‐operative identification and management of patients with unhealthy alcohol intake 围手术期不健康酒精摄入患者的识别和处理
IF 10.7 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2025-01-09 DOI: 10.1111/anae.16530
Matthew J. A. Jenkins, Stephen M. Kinsella, Matthew D. Wiles, Brijesh Srivastava, Catherine Griffiths, Jacquelyn Lewin, Stephen Usher, Gautam Mehta, Abi Berger, Dereck Gondongwe, Isra Hassan
SummaryIntroductionThis consensus statement gives practical advice for the safe management of patients with harmful alcohol intake undergoing elective and emergency surgery. The wide spectrum of alcohol‐related organ dysfunction observed in this cohort of patients may have a profound impact on care, and the additional effects of alcohol withdrawal may further exacerbate postoperative morbidity and mortality.MethodsA working party was assembled based on clinical and/or academic expertise in the area. Recommendations were formulated using a modified Delphi process. An initial list of recommendations was produced following targeted literature reviews for all relevant phases of patient care throughout the peri‐operative pathway. These recommendations were distributed among the authors who rated each as ‘include’, ‘exclude’; or ‘revise’. Recommendations with ≥ 75% inclusion decision were included.ResultsThe working party produced a list of 10 key peri‐operative management recommendations. These include recommendations on how to screen effectively for excessive alcohol usage in the surgical population. To achieve this, a validated point‐of‐care tool is used with additional weighting provided by considering surgical urgency. This is combined with the use of scoring systems to facilitate decisions regarding peri‐operative care including postoperative location. This document also provides clear explanation of the physiological and pharmacological issues relating to alcohol excess, highlighting the direct effects of alcohol and its secondary effects on organ systems.DiscussionThis consensus statement offers strategies and solutions to minimise the impact of harmful alcohol intake on the safe conduct of anaesthesia.
本共识声明为接受选择性和紧急手术的有害酒精摄入患者的安全管理提供了实用建议。在这组患者中观察到的广泛的酒精相关器官功能障碍可能对护理产生深远的影响,并且酒精戒断的额外影响可能进一步加剧术后发病率和死亡率。方法根据该领域的临床和/或学术专业知识组建工作组。建议是使用改进的德尔菲过程制定的。针对围手术期患者护理的所有相关阶段进行有针对性的文献综述后,产生了一份初步建议清单。这些建议在作者之间进行分配,作者将每个建议分为“包括”、“排除”;或“修改”。纳入决策≥75%的推荐。结果工作组提出了10项围手术期关键管理建议。这些建议包括如何有效筛查手术人群中过量饮酒的建议。为了实现这一目标,使用经过验证的护理点工具,并考虑手术紧迫性提供额外的权重。这与评分系统的使用相结合,以促进围手术期护理的决策,包括术后定位。本文还提供了与酒精过量有关的生理和药理学问题的清晰解释,强调了酒精的直接影响及其对器官系统的次生影响。本共识声明提供了策略和解决方案,以尽量减少有害酒精摄入对麻醉安全行为的影响。
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Anaesthesia
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