American journal of therapeutics最新文献

{"title":"Percutaneous Versus Surgical Cutdown Access for Endovascular Aneurysm Repair: A Meta-Analysis of Randomized Controlled Trials.","authors":"Muhammad Abdullah Ali, Fazia Khattak, Saqib Hayat Khan, Abdullah Afridi, Umama Alam, Sufyan Shahid, Allahdad Khan, Zaryab Bacha","doi":"10.1097/MJT.0000000000001961","DOIUrl":"10.1097/MJT.0000000000001961","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e107-e110"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Decrease of PD-L1 Expression Affects the Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With Lung Squamous Cell Carcinoma.","authors":"Yin Jie, Du Mingzhan, Gong Yinhua, Shen Dan","doi":"10.1097/MJT.0000000000001965","DOIUrl":"10.1097/MJT.0000000000001965","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e105-e107"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12767625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resistance to Antibiotics, Complications, and Mortality of Infective Endocarditis in a Consecutive Cohort of 178 Cases.","authors":"Alexandru Covaciu, Elena Bobescu, Valentina Benza, Elena Lorena Pepine, Madalina Ivascu, Andreea Amalia Tomulescu, Emanuel Cojocariu, Lilia Aida Mahjoub, Nicoleta Cojocaru, Liliana Rogozea, Lorena Dima, Christian Gabriel Strempel, Horatiu Rus","doi":"10.1097/MJT.0000000000002094","DOIUrl":"https://doi.org/10.1097/MJT.0000000000002094","url":null,"abstract":"<p><strong>Background: </strong>Infective endocarditis is a severe cardiac infection disease with high morbidity and mortality, remained largely unchanged over the past 2 decades with an increased incidence in the last years.</p><p><strong>Study question: </strong>Was to evaluate the main causes of increased incidence and antibiotic resistance and the role of biomarkers in infective endocarditis.</p><p><strong>Study design: </strong>Patients with infective endocarditis admitted in Cardiology Department were evaluated regarding the annual incidence and characteristics in the last 8 years, to identify the causes of the increased incidence of this disease.</p><p><strong>Measures and outcomes: </strong>We enrolled 178 patients diagnosed with infective endocarditis admitted in hospital in the last 8 years. The data included patient's demographic data, medical history, presence of preexisting risk, or associated systemic diseases.</p><p><strong>Results and discussion: </strong>Infective endocarditis was diagnosed twice as frequently in urban areas with two-thirds of patients being male and 4 of 5 patients being older than 60 years. The most common disease associated was previous valvopathies and the most affected aortic native valve in 1 of 5 cases. Inflammation markers were predictive for diagnosis, complication, and prognosis in patients with IE. The highest frequencies pathogens were Staphylococcus spp., Enterococcus spp., and Streptococcus spp. Two-thirds of patients needed reserve antibiotics such as glycopeptides and/or carbapenems because of antibiotic resistance. The predictors for in-hospital mortality were the following: old age, heart and renal failure, markers of organ dysfunction, persistence of infection, and high inflammatory markers.</p><p><strong>Conclusions: </strong>Infective endocarditis was diagnosed more frequently in urban areas, in male, and those aged older than 60 years. Previous valvopathies was most common associated disease, and aortic native valve was the most affected. Persistent infection and inflammation were predictors for bad prognosis in patients with infective endocarditis. The top 3 highest frequencies pathogens were Staphylococcus spp., Enterococcus spp., and Streptococcus spp., and an increase in antibiotic resistance has been recorded.</p>","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 1","pages":"e1-e14"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of GLP-1 Agonists in Psoriatic Arthritis: Erratum.","authors":"Nathaniel Gilbert, Halah Alfatlawi, Hajera Amatul-Raheem, Jennifer Delucia, Nezam Altorok","doi":"10.1097/MJT.0000000000002083","DOIUrl":"https://doi.org/10.1097/MJT.0000000000002083","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 1","pages":"e119"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of SGLT2 Inhibitors and GLP-1 Receptor Agonists on the Risk of Atrial Fibrillation in Patients With Type 2 Diabetes: A Systematic Review and Meta-analysis.","authors":"Akash Kumar, Mariam Shahabi, Saad Ahmed Waqas, Nisha Kumari, Nimurta Madhwani, Raheel Ahmed, Ram","doi":"10.1097/MJT.0000000000001968","DOIUrl":"10.1097/MJT.0000000000001968","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e113-e115"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colchicine-Induced Severe Bone Marrow Suppression: Treatment With Platelet Suspensions.","authors":"İbrahim Altundağ, Semih Korkut, Aynur Şahin","doi":"10.1097/MJT.0000000000001886","DOIUrl":"10.1097/MJT.0000000000001886","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e55-e56"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145707000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Zanubrutinib in B-Cell Malignancies: A Single-Arm Meta-Analysis.","authors":"Rongrong Chen, Shiquan Yu, Yun Liao, Jiayue Liu, Chunlan Huang","doi":"10.1097/MJT.0000000000001872","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001872","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 1","pages":"e77-e78"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Omalizumab Treatment for Pregnancy With Refractory Acute Urticaria.","authors":"Qiancheng Deng, Yanyan Wu, Su Wang, Hong Fang, Jianjun Qiao","doi":"10.1097/MJT.0000000000001994","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001994","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 1","pages":"e60-e62"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obinutuzumab in Patients With Active Lupus Nephritis: A Meta-Analysis.","authors":"Allahdad Khan, Shree Rath, Shaista Khadim, Zahid Ullah, Muhammad Junaid, Syed Ahtisham Halim, Asad Ali Ahmed Cheema","doi":"10.1097/MJT.0000000000001988","DOIUrl":"10.1097/MJT.0000000000001988","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e115-e118"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Therapeutic Landscape of Salvia fruticosa: A Systematic Exploration of Pharmacology and Clinical Promise.","authors":"Fazil Ahmad","doi":"10.1097/MJT.0000000000001927","DOIUrl":"10.1097/MJT.0000000000001927","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e100-e101"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145172276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}