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American journal of therapeutics最新文献

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Sorafenib-Associated Bilateral Osteonecrosis of the Femoral Head. 索拉非尼(Sorafenib)相关的双侧股骨头骨坏死。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 DOI: 10.1097/MJT.0000000000001751
Tanju Kapagan, Nilufer Bulut, Ahmet Unsal, Gokmen Umut Erdem
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引用次数: 0
Hair Lightening Following Heptaminol Treatment in a Hemodialysis Patient. 血液透析患者接受庚胺醇治疗后头发变白。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 DOI: 10.1097/MJT.0000000000001746
Yasmine Salem Mahjoubi, Imen Hamza, Imen Aouinti, Widd Kaabi, Ghozlane Lakhoua, Ahmed Zaiem, Sihem El Aidli
{"title":"Hair Lightening Following Heptaminol Treatment in a Hemodialysis Patient.","authors":"Yasmine Salem Mahjoubi, Imen Hamza, Imen Aouinti, Widd Kaabi, Ghozlane Lakhoua, Ahmed Zaiem, Sihem El Aidli","doi":"10.1097/MJT.0000000000001746","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001746","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 5","pages":"e602-e604"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thalidomide Combined With Minocycline for Successful Treatment of Morbihan Syndrome Patients in Two Cases. 沙利度胺联合米诺环素成功治疗两例莫尔比昂综合征患者
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1097/MJT.0000000000001759
Juan-Juan Liu, Shi Yan, Hong-Xing Guo, Hai-Zhen Hui
{"title":"Thalidomide Combined With Minocycline for Successful Treatment of Morbihan Syndrome Patients in Two Cases.","authors":"Juan-Juan Liu, Shi Yan, Hong-Xing Guo, Hai-Zhen Hui","doi":"10.1097/MJT.0000000000001759","DOIUrl":"10.1097/MJT.0000000000001759","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e626-e628"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and Efficacy of Torsemide Versus Furosemide in Patients With Heart Failure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Real-World Data. 托西米与呋塞米治疗心力衰竭患者的安全性和有效性:随机对照试验和真实世界数据的系统回顾和元分析》。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 Epub Date: 2024-08-09 DOI: 10.1097/MJT.0000000000001735
Farah Yasmin, Abdul Moeed, Eman Ali, Farwa Zaidi, Johar Abbas, Maham Iqbal, Muhammad Umar, M Chadi Alraies
{"title":"Safety and Efficacy of Torsemide Versus Furosemide in Patients With Heart Failure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Real-World Data.","authors":"Farah Yasmin, Abdul Moeed, Eman Ali, Farwa Zaidi, Johar Abbas, Maham Iqbal, Muhammad Umar, M Chadi Alraies","doi":"10.1097/MJT.0000000000001735","DOIUrl":"10.1097/MJT.0000000000001735","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e584-e587"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141909748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucagon for Esophageal Foreign Body Impaction: A Systematic Review and Meta-analysis of Randomized Controlled Trials. 胰高血糖素治疗食管异物嵌塞:随机对照试验的系统回顾和元分析》。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 DOI: 10.1097/MJT.0000000000001747
AbdiGhani Ismail, Azizullah Beran, Saad Saadat, Diego Izquierdo Veraza, John J Guardiola
{"title":"Glucagon for Esophageal Foreign Body Impaction: A Systematic Review and Meta-analysis of Randomized Controlled Trials.","authors":"AbdiGhani Ismail, Azizullah Beran, Saad Saadat, Diego Izquierdo Veraza, John J Guardiola","doi":"10.1097/MJT.0000000000001747","DOIUrl":"10.1097/MJT.0000000000001747","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 5","pages":"e605-e607"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Proton Pump Inhibitors Cause Myocardial Infarction and Stroke? Time-Variant Analyses Can Resolve the Debate. 质子泵抑制剂会导致心肌梗死和中风吗?时变分析可解决争论。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 Epub Date: 2024-07-17 DOI: 10.1097/MJT.0000000000001717
Nancy L Sloan, Ahmad Sabra, Henry S Sacks, Christopher R Dasaro, Rolando C Antonio, Erin Thanik, Moshe Z Shapiro, John T Doucette, Jacqueline M Moline, Benjamin J Luft, Iris G Udasin, Denise J Harrison, Michael A Crane, Andrew C Todd, Susan L Teitelbaum
{"title":"Do Proton Pump Inhibitors Cause Myocardial Infarction and Stroke? Time-Variant Analyses Can Resolve the Debate.","authors":"Nancy L Sloan, Ahmad Sabra, Henry S Sacks, Christopher R Dasaro, Rolando C Antonio, Erin Thanik, Moshe Z Shapiro, John T Doucette, Jacqueline M Moline, Benjamin J Luft, Iris G Udasin, Denise J Harrison, Michael A Crane, Andrew C Todd, Susan L Teitelbaum","doi":"10.1097/MJT.0000000000001717","DOIUrl":"10.1097/MJT.0000000000001717","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e573-e577"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141625736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Afatinib in Advanced Lung Squamous Cancer Harboring HER2 Mutation in Exon 17 Plus Amplification. 阿法替尼治疗外显子 17 中携带 HER2 基因突变和扩增的晚期肺鳞癌
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 DOI: 10.1097/MJT.0000000000001740
Yu-Ji Wang, Da-Xiong Zeng
{"title":"Afatinib in Advanced Lung Squamous Cancer Harboring HER2 Mutation in Exon 17 Plus Amplification.","authors":"Yu-Ji Wang, Da-Xiong Zeng","doi":"10.1097/MJT.0000000000001740","DOIUrl":"10.1097/MJT.0000000000001740","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 5","pages":"e594-e596"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Interventions and Hemodynamic Monitoring in the Setting of Left Ventricular Systolic Heart Failure in Children: Insights From a Physiologic Simulator. 儿童左心室收缩性心力衰竭的临床干预和血流动力学监测:生理模拟器的启示。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 DOI: 10.1097/MJT.0000000000001711
Rohit S Loomba, Fabio Savorgnan, Sebastian Acosta, Justin J Elhoff, Juan S Farias, Enrique G Villarreal, Saul Flores

Background: In pediatric critical care, vasoactive/inotropic support is widely used in patients with heart failure, but it remains controversial because the influence of multiple medications and the interplay between their inotropic and vasoactive effects on a given patient are hard to predict. Robust evidence supporting their use and quantifying their effects in this group of patients is scarce.

Study question: The aim of this study was to characterize the effect of vasoactive medications on various cardiovascular parameters in pediatric patient with decreased ejection fraction.

Study design: Clinical-data based physiologic simulator study.

Measure and outcomes: We used a physics-based computer simulator for quantifying the response of cardiovascular parameters to the administration of various types of vasoactive/inotropic medications in pediatric patients with decreased ejection fraction. The simulator allowed us to study the impact of increasing medication dosage and the simultaneous administration of some vasoactive agents. Correlation and linear regression analyses yielded the quantified effects on the vasoactive/inotropic support.

Results: Cardiac output and systemic venous saturation significantly increased with the administration of dobutamine and milrinone in isolation, and combination of milrinone with dobutamine, dopamine, or epinephrine. Both parameters decreased with the administration of epinephrine and norepinephrine in isolation. No significant change in these hemodynamic parameters was observed with the administration of dopamine in isolation.

Conclusions: Milrinone and dobutamine were the only vasoactive medications that, when used in isolation, improved systemic oxygen delivery. Milrinone in combination with dobutamine, dopamine, or epinephrine also increased systemic oxygen delivery. The induced increment on afterload can negatively affect systemic oxygen delivery.

背景:在儿科重症监护中,血管活性/肌力支持被广泛应用于心力衰竭患者,但由于很难预测多种药物的影响及其对特定患者肌力和血管活性效应之间的相互作用,因此仍存在争议。支持在这类患者中使用这些药物并量化其效果的有力证据十分稀少:本研究旨在确定血管活性药物对射血分数降低的儿科患者各种心血管参数的影响:研究设计:基于临床数据的生理模拟器研究:我们使用基于物理的计算机模拟器,量化射血分数下降的儿科患者在服用各种类型的血管活性药物/肌注药物后心血管参数的反应。通过模拟器,我们可以研究增加药物剂量和同时使用某些血管活性药物的影响。相关性和线性回归分析得出了对血管活性/肌力支持的量化影响:结果:单独使用多巴酚丁胺和米力农,以及米力农与多巴酚丁胺、多巴胺或肾上腺素联合使用时,心输出量和全身静脉饱和度明显增加。单独使用肾上腺素和去甲肾上腺素时,这两个参数都会降低。在单独使用多巴胺时,这些血流动力学参数没有明显变化:结论:米力农和多巴酚丁胺是单独使用时唯一能改善全身氧输送的血管活性药物。米力农与多巴酚丁胺、多巴胺或肾上腺素联合使用也能增加全身供氧量。诱导的后负荷增加会对全身供氧量产生负面影响。
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引用次数: 0
Combination of Somatostatin and Rectal Nonsteroidal Anti-Inflammatory Drugs for Prevention of Postendoscopic Retrograde Cholangiopancreatography Pancreatitis in High-Risk Patients: A Meta-Analysis of Randomized Controlled Trials. 联合使用体生长抑素和直肠非甾体抗炎药预防高危患者内镜逆行胰胆管造影术后胰腺炎:随机对照试验的 Meta 分析。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 DOI: 10.1097/MJT.0000000000001734
Fouad Jaber, Ahmed-Jordan Salahat, Saqr Alsakarneh, Tala Alsharaeh, Mohammad Jaber, Manesh Kumar Gangwani, Islam Mohamed, Mohammad Aldiabat, Yassine Kilani, Hassam ALi, Hassan Ghoz
{"title":"Combination of Somatostatin and Rectal Nonsteroidal Anti-Inflammatory Drugs for Prevention of Postendoscopic Retrograde Cholangiopancreatography Pancreatitis in High-Risk Patients: A Meta-Analysis of Randomized Controlled Trials.","authors":"Fouad Jaber, Ahmed-Jordan Salahat, Saqr Alsakarneh, Tala Alsharaeh, Mohammad Jaber, Manesh Kumar Gangwani, Islam Mohamed, Mohammad Aldiabat, Yassine Kilani, Hassam ALi, Hassan Ghoz","doi":"10.1097/MJT.0000000000001734","DOIUrl":"10.1097/MJT.0000000000001734","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 5","pages":"e628-e633"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and Safety of Etrolizumab in the Treatment of Moderate to Severe Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 依托利珠单抗治疗中度至重度溃疡性结肠炎的有效性和安全性:随机对照试验的系统回顾和元分析》。
IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2024-09-01 DOI: 10.1097/MJT.0000000000001741
Fouad Jaber, Saqr Alsakarneh, Mohammed Ayyad, Tala Alsharaeh, Ahmed-Jordan Salahat, Mohammad Jaber, Yassine Kilani, Mohammad Aldiabat, Manesh Kumar Gangwani, Yazan Abboud, Ahmed Fares, Dushyant Singh Dahiya, Mohamed Ahmed, Richa Shukla
{"title":"Efficacy and Safety of Etrolizumab in the Treatment of Moderate to Severe Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Fouad Jaber, Saqr Alsakarneh, Mohammed Ayyad, Tala Alsharaeh, Ahmed-Jordan Salahat, Mohammad Jaber, Yassine Kilani, Mohammad Aldiabat, Manesh Kumar Gangwani, Yazan Abboud, Ahmed Fares, Dushyant Singh Dahiya, Mohamed Ahmed, Richa Shukla","doi":"10.1097/MJT.0000000000001741","DOIUrl":"10.1097/MJT.0000000000001741","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 5","pages":"e596-e600"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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American journal of therapeutics
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