Pub Date : 1986-12-01DOI: 10.1016/S0307-742X(21)00570-1
{"title":"Dedication","authors":"","doi":"10.1016/S0307-742X(21)00570-1","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00570-1","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136542912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Up to 60% of patients with symptomatic Paget's disease develop articular symptoms in its course. Effective therapy may depend on accurate localization of all symptoms and many patients will have an overlap of bone and articular symptoms which may prove impossible to separate. Over the past 10 years there have been major advances in drug therapy for Paget's disease but still the ideal agent is not currently available. Analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) remain the basis of treatment for arthritis and there is no evidence yet that calcitonin or the diphosphonates will inhibit its development. Orthopaedic procedures, especially osteotomy for deformity and joint replacement may be indicated in selected cases.
{"title":"The rheumatology of Paget's disease.","authors":"J Winfield","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Up to 60% of patients with symptomatic Paget's disease develop articular symptoms in its course. Effective therapy may depend on accurate localization of all symptoms and many patients will have an overlap of bone and articular symptoms which may prove impossible to separate. Over the past 10 years there have been major advances in drug therapy for Paget's disease but still the ideal agent is not currently available. Analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) remain the basis of treatment for arthritis and there is no evidence yet that calcitonin or the diphosphonates will inhibit its development. Orthopaedic procedures, especially osteotomy for deformity and joint replacement may be indicated in selected cases.</p>","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14114316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The knowledge of the endocrinological status of postmenopausal osteoporosis has considerably progressed in recent years, although many issues remain to be settled. Better knowledge will foster better understanding of the pathogenesis of this disabling condition, and will be of help in designing more effective ways of preventive therapy in a disease where a recent survey showed that 34% of the physicians were unsure as to whether or not it is preventable. Other approaches dealing with exercise, fitness, nutrition, environment, genetic and racial background, or the quality of bone, should not be neglected. Many of these other factors may also be related, at least partially, to the hormonal status.
{"title":"Endocrinological status of postmenopausal osteoporosis.","authors":"C Nagant de Deuxchaisnes, J P Devogelaer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The knowledge of the endocrinological status of postmenopausal osteoporosis has considerably progressed in recent years, although many issues remain to be settled. Better knowledge will foster better understanding of the pathogenesis of this disabling condition, and will be of help in designing more effective ways of preventive therapy in a disease where a recent survey showed that 34% of the physicians were unsure as to whether or not it is preventable. Other approaches dealing with exercise, fitness, nutrition, environment, genetic and racial background, or the quality of bone, should not be neglected. Many of these other factors may also be related, at least partially, to the hormonal status.</p>","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14210191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1986-12-01DOI: 10.1016/S0307-742X(21)00572-5
Charles Nagant De Deuxchaisnes Jean-Pierre Devogelaer
The knowledge of the endocrinological status of postmenopausal osteoporosis has considerably progressed in recent years, although many issues remain to be settled. Better knowledge will foster better understanding of the pathogenesis of this disabling condition, and will be of help in designing more effective ways of preventive therapy in a disease where a recent survey showed that 34% of the physicians were unsure as to whether or not it is preventable. Other approaches dealing with exercise, fitness, nutrition, environment, genetic and racial background, or the quality of bone, should not be neglected. Many of these other factors may also be related, at least partially, to the hormonal status.
{"title":"Endocrinological Status of Postmenopausal Osteoporosis","authors":"Charles Nagant De Deuxchaisnes Jean-Pierre Devogelaer","doi":"10.1016/S0307-742X(21)00572-5","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00572-5","url":null,"abstract":"<div><p>The knowledge of the endocrinological status of postmenopausal osteoporosis has considerably progressed in recent years, although many issues remain to be settled. Better knowledge will foster better understanding of the pathogenesis of this disabling condition, and will be of help in designing more effective ways of preventive therapy in a disease where a recent survey showed that 34% of the physicians were unsure as to whether or not it is preventable. Other approaches dealing with exercise, fitness, nutrition, environment, genetic and racial background, or the quality of bone, should not be neglected. Many of these other factors may also be related, at least partially, to the hormonal status.</p></div>","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136543172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1986-12-01DOI: 10.1016/S0307-742X(21)00581-6
{"title":"Index","authors":"","doi":"10.1016/S0307-742X(21)00581-6","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00581-6","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0307-742X(21)00581-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136543176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Musculoskeletal manifestations of primary hyperparathyroidism.","authors":"A K Bhalla","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14210051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolic and endocrine aspects of rheumatic disease.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14401661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1986-12-01DOI: 10.1016/S0307-742X(21)00576-2
J. Winfield
Up to 60% of patients with symptomatic Paget's disease develop articular symptoms in its course. Effective therapy may depend on accurate localization of all symptoms and many patients will have an overlap of bone and articular symptoms which may prove impossible to separate. Over the past 10 years there have been major advances in drug therapy for Paget's disease but still the ideal agent is not currently available. Analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs) remain the basis of treatment for arthritis and there is no evidence yet that calcitonin or the diphosphonates will inhibit its development. Orthopaedic procedures, especially osteotomy for deformity and joint replacement may be indicated in selected cases.
{"title":"The Rheumatology of Paget's Disease","authors":"J. Winfield","doi":"10.1016/S0307-742X(21)00576-2","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00576-2","url":null,"abstract":"<div><p>Up to 60% of patients with symptomatic Paget's disease develop articular symptoms in its course. Effective therapy may depend on accurate localization of all symptoms and many patients will have an overlap of bone and articular symptoms which may prove impossible to separate. Over the past 10 years there have been major advances in drug therapy for Paget's disease but still the ideal agent is not currently available. Analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs) remain the basis of treatment for arthritis and there is no evidence yet that calcitonin or the diphosphonates will inhibit its development. Orthopaedic procedures, especially osteotomy for deformity and joint replacement may be indicated in selected cases.</p></div>","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136543174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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