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Clinics in rheumatic diseases
Pub Date : 1986-04-01 DOI: 10.1016/S0307-742X(21)00614-7
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引用次数: 0
Metabolic bone disease and Paget's disease in the elderly. Part II: Paget's disease. 代谢性骨病和老年佩吉特病。第二部分:佩吉特病。
Clinics in rheumatic diseases
Pub Date : 1986-04-01
R L Merkow, J M Lane
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引用次数: 0
Metabolic bone disease and Paget's disease in the elderly. Part I: Metabolic bone disease. 代谢性骨病和老年佩吉特病。第一部分:代谢性骨病。
Clinics in rheumatic diseases
Pub Date : 1986-04-01
J M Lane, J R Werntz, J H Healey, V J Vigorita
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引用次数: 0
Index 指数
Clinics in rheumatic diseases
Pub Date : 1986-04-01 DOI: 10.1016/S0307-742X(21)00633-0
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引用次数: 0
Polymyalgia rheumatica. Polymyalgia rheumatica .
Clinics in rheumatic diseases
Pub Date : 1986-04-01
B Olhagen
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引用次数: 0
Disease-modifying Agents and Immunosuppressive Drugs in the Elderly 老年人的疾病调节剂和免疫抑制药物
Clinics in rheumatic diseases
Pub Date : 1986-04-01 DOI: 10.1016/S0307-742X(21)00630-5
Joseph W. O'callaghan, Peter M. Brooks

Disease-modifying and immunosuppressive therapies are required for elderly patients with rheumatic disorders. The evidence to date suggests that the criteria for choosing a particular drug is not vastly different from the choice in younger patients, and that the elderly have a similar response. More care is required in monitoring elderly patients on immunosuppressive drugs because of the potential for increased adverse reactions consequent on reduced functional capacity of major end organs. There is little data available to judge relative efficacy of these drugs in the elderly and with the ‘greying’ of the population these data should be sought after.

With careful individual choice of drug and regular reassessment for effect and adverse drug reactions, many elderly patients with rheumatic diseases can obtain useful benefit from these agents.

老年风湿病患者需要疾病改善和免疫抑制治疗。迄今为止的证据表明，选择一种特定药物的标准与年轻患者的选择没有太大的不同，老年人的反应也类似。在监测使用免疫抑制药物的老年患者时需要更多的注意，因为由于主要终末器官功能能力的降低，可能会增加不良反应。几乎没有可用的数据来判断这些药物对老年人的相对疗效，随着人口的“老龄化”，应该寻求这些数据。通过谨慎的个体化药物选择和定期重新评估疗效和药物不良反应，许多老年风湿病患者可以从这些药物中获得有益的益处。
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引用次数: 0
The Immunology of Ageing 衰老的免疫学
Clinics in rheumatic diseases
Pub Date : 1986-04-01 DOI: 10.1016/S0307-742X(21)00617-2
Peter M. Ford
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引用次数: 0
Connective Tissue Disease in the Elderly 老年人结缔组织疾病
Clinics in rheumatic diseases
Pub Date : 1986-04-01 DOI: 10.1016/S0307-742X(21)00618-4
Mary Betty Stevens

The prevalence of the inflammatory disorders of connective tissue in the older age group is quite likely underestimated at the present time; and, in most instances, age-related factors influencing clinical expression and auto-reactivity have not been intensively studied.

The array of connective tissue disease that usually targets the young adult emerges in the older age group as well; and, selectively in the elderly, GCA and PMR are found. The association of malignancy with PM/DM is increased with advanced age.

In view of the therapeutic implications, early diagnosis is essential, but this can be especially difficult in the setting of problems related to the ageing process.

目前，结缔组织炎症性疾病在老年人群中的患病率很可能被低估了;而且，在大多数情况下，影响临床表现和自身反应的年龄相关因素尚未得到深入研究。通常针对年轻人的一系列结缔组织疾病也出现在老年群体中;在老年人中，选择性地发现了GCA和PMR。恶性肿瘤与PM/DM的相关性随着年龄的增长而增加。鉴于治疗意义，早期诊断是必不可少的，但在与衰老过程有关的问题的设置中，这可能特别困难。
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引用次数: 0
Part II: Paget's Disease 第二部分:佩吉特病
Clinics in rheumatic diseases
Pub Date : 1986-04-01 DOI: 10.1016/S0307-742X(21)00621-4
Robert L. Merkow, Joseph M. Lane
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引用次数: 0
Ageing in Relation to the Pathogenesis of Osteoarthritis 衰老与骨关节炎发病机制的关系
Clinics in rheumatic diseases
Pub Date : 1986-04-01 DOI: 10.1016/S0307-742X(21)00623-8
Kenneth D. Brandt, Rose S. Fife
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引用次数: 0
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